Pathogen Variation and Genomics

Introduction

Our group studies the genome biology and molecular biology of clinically- and ecologically-important bacterial pathogens. We focus on high-risk human pathogens, including Vibrio species, hypervirulent and multidrug-resistant Enterobacteriaceae, and other Gram-negative organisms. Common to all of this work is a need to understand how genes and DNA are exchanged between these pathogens through horizontal gene transfer. We use a combination of experimental and computational approaches, to understand molecular mechanisms in the lab, and then to see how these vary across the large volumes of bacterial genome sequences available in public databases

Read More

Principal Investigator Profile