Selected Publications:

The hybrid genome of Saccharomyces pastorianus: a current perspective Yeast (2017) [Chandre Monerawela and Ursula Bond] DOI: 10.1002/yea.3250

Recombination sites on hybrid chromosomes in S. pastorianus share common sequence motifs and define a complex evolutionary relationship between Group I and II lager yeasts, FEMS Yeast Research. FEMS Yeast Research (2017)[Chandre Monerawela and Ursula Bond] doi: 10.1093/femsyr/fox047

'Brewing up a storm: The genomes of lager yeasts and how they evolved', Biotechnology Advances(2017), 1-8 [Chandre Monerawela and Ursula Bond]

Antifungal activity of a synthetic human b -defensin 3 and potential applications in cereal-based products', Innovative Food Science and Emerging Technologies, 38 (2016), [Thery T, Tharappel J.C, Kraszewska J, Beckett M, Bond U, Arendt E.K]

'Comparative analysis of the antimicrobial activities of plant defensin-like and ultrashort peptides against food-spoiling bacteria', Applied and Environmental Microbiology, 82, 14 (2016), 4288-98 [Kraszewska J, Beckett M.C, James T.C, Bond U]

'Loss Of Lager Specific Genes And Subtelomeric Regions Define Two Different Saccharomyces cerevisiae Lineages for Saccharomyces pastorianus Group I and II Strains.', FEMS Yeast Research, 15, 2, (2015), pii: fou008. doi: 10.1093/femsyr/fou008 . [Monerawela, C., James, T.C., Wolfe, K., and U. Bond]

'Engineering Saccharomyces pastorianus for the co-utilisation of xylose and cellulose from biomass.', Microbial Cell Factories, 14, 61 (2015), 1-11 [Kricka, W., Fitzpatrick, J., T.C. James and U. Bond]

'Challenges for the Production of Bioethanol from Biomass using Recombinant Yeasts', Advances in Applied Microbiology, 92 (2015), 89-125 [Kricka, W., Fitzpatrick, J., and U. Bond]

'Expression of three Trichoderma reesei cellulase genes in Saccharomyces pastorianus for the development of a two-step process of hydrolysis and fermentation of cellulose ', Journal of Applied Microbiology, epub 03/14 (2014), 117, 1, 96–108 [Fitzpatrick, J. Kricka, W., James, T.C. and U. Bond]

'In situ production of human b -defensin-3 in lager yeasts provides bactericidal activity against beer-spoiling bacteria under fermentation conditions.', Journal of Applied Microbiology, 116, 2 (2014), 368-79 [James TC, Gallagher L, Titze J, Bourke P, Kavanagh J, Arendt E, Bond U.]

'Generation of New Genotypic and Phenotypic Features in Artificial and Natural Yeast Hybrids', Food Technology and Biotechnology, 52, 1 (2014), 46-57 [Pfliegler, W.P., Atanasova, L., Karanyicz, E., Sipiczki, M. Bond, U., Druzhinina,I.S., Sterflinger, K., and K. Lopandic]

'Metabolic engineering of yeasts by heterologous enzyme production for degradation of cellulose and hemicellulose from biomass: a perspective', Frontiers in Microbiology, 5 (2014), 174 doi: 10.3389/fmicb.2014.00174.  [Kricka, W., Fitzpatrick, J. and U. Bond. ]

'Molecular Mimics of the Tumour Antigen MUC1', PLOS One, 7, 11 (2012), doi: 10.1371/journal.pone.0049728 [James, T.C. and U, Bond]

'Phage display biopanning identifies the translation initiation and elongation factors (IF1- a and eIF-3) as components of Hsp70-peptide complexes in breast tumour cells.', Cell Stress Chaperones, 17, 2 (2012), 145-56 [Siebke C, James TC, Cummins R, O'Grady T, Kay E, Bond U.]

'The PolyA tail length of yeast histone mRNAs varies during the cell cycle and is influenced by Sen1p and Rrp6p', Nucleic Acids Research, 40, 6 (2012), 2700-11 [Suzanne Beggs, Tharappel C. James and Ursula Bond]

'Recombination between Homeologous Chromosomes in Lager Yeasts leads to Loss of Function of the Hybrid GPH1 Gene.', Applied and Environmental Microbiology, 75, 13 (2009), 4573-9 [Usher, J and Bond, U.]

'The Genomes of Lager Yeasts', Advances in Applied Microbiology, Laskin, A., Sariaslani, S. and Gadd, G. eds, Academic Press (2010), [Bond, U.]

'The complex and dynamic genomes of industrial yeasts. ', FEMS Microbiol Lett., 293, 1, 1-10 (2009), [Querol, A and Bond U]

'Lager yeasts possess dynamic genomes that undergo rearrangements and gene amplification in response to stress.', Current Genetics, 53, 3 (2008), 139-152 [Tharappel, J, Usher, J, Campbell, S and Bond, U.]

'Deletion of the nuclear exosome component RRP6 leads to continued accumulation of the histone mRNA HTB1 in S-phase of the cell cycle in Saccharomyces cerevisiae.', Nucleic Acids Research, 35, 18 (2007), 6268-79 [Canavan, R and U. Bond]

'Stressed Out! The effects of environmental stress on mRNA metabolism.', FEMS Yeast Research, 6 (2006), 160-170 [U. Bond]

'Principles and applications of genomics and proteomics in the analysis of industrial yeasts.', The Yeast Handbook, A. Querol eds, Heidleberg, Springer-Verlag (2006), [A. Blomberg and U. Bond]

'A Novel method to identify and characterise peptide mimotopes of heat shock protein 70-associated antigens.', Journal of Immune Based Therapies and Vaccines, 4, 12 (2006), 2-13 [Arnaiz B, Madrigal-Estebas L, Todryk S, James TC, Doherty DG, Bond U.]

'Structural mimics of heat shock protein 70- associated peptides from breast tumour cells can prime T-cells to respond to tumour antigens', European Journal of Cancer, 2 (2004), 79 [Arnaiz, B., L. Madrigal, D. Doherty, T.C.James and U. Bond]

'Aneuploidy and copy number breakpoints in the genome of lager yeasts mapped by microarray hybridisation', Current Genetics, 24 (2004), 360-370 [T.C. James, D. Donnelly and U. Bond]

'Transcription profile of a brewery yeast under fermentation conditions', Journal of Applied Microbiology., 94 (2003), 432-488 [T.C. James, S. Campbell, D. Donnelly and U. Bond]

'A sequence element downstream of the yeast HTB1 gene connects mRNA'3 end processing, transcription termination and cell cycle regulation of a histone gene', Mol. Cell Biol., 22 (2002), 8415-25 [Campbell, S., M. li del Olmo, Beglan, P. and U. Bond]

'Comparative Analysis of global gene expression in lager and laboratory yeast strains grown in wort', Proc. of IEEE: Challenges in Functional Genomics, 90 (2002), 1887-1899 [T.C. James, S. Campbell, and U. Bond]

'A model organism for genomic and postgenomic studies', IEEE: Engineering in Medicine and Biology, 20 (2001), 22-32 [Bond, U., S. Campbell and T.C. James]

'Bio-informatical analysis of histone 3'end processing in Saccharomycesmcerevisiae:identification of U7-like RNAs', Biochem. Soc. Trans., 28 (2000), 41 [Campbell, S. and U. Bond]

'Dynamic changes in small nuclear ribonucleoproteins of heat-stressed and thermotolerant HeLa cells', Int. J. Biochem. Cell. Biol., 32 (2000), 643-56 [Bond, U. and T. C. James]

'The stress response is repressed during fermentation in brewery strains of yeast', J. Appl. Microbiology, 88 (2000), 746-55 [Brosnan, T., T. C. James, D. Donnelly and U. Bond]

'Reassembly and protection of small nuclear ribonucleoprotein particles by heat shock proteins in yeast cells', RNA, 5 (1999), 1586-96[Bracken A. and U. Bond]

'Characterization of a new class of transcribed repetitive DNA sequence which exists as a hybrid with HP1 mRNA; potential for site specific recombination in Drosophila melanogaster', J. Insect Mol. Biol. and Biochem., 25 (1995), 331-337 [Ngan,V, G. Vacano, U. Bond, and T.C. James]

'The steady state levels and structure of the U7 snRNP are constant during the human cell cycle: lack of cell cycle regulation of histone mRNA 3' end formation', Cell. Mol. Biol. Res., 40 (1994), 27-34[Bond, U, and T. Yario]

'Point mutations in the stem-loop at the 3' end of mouse histone mRNA reduce expression by reducing the efficiency of 3' end formation', Mol. Cell Biol.,, 14 (1994), 1709-1720 [N.P. Pandey, J. Sun, A.S. Williams, V.D. Brown, U. Bond and W. F. Marzluff]

'Analysis of the basepairing interaction between mammalian U7 and the downstream element of histone pre-mRNAs', J. Cellular Biochem(1991), 256, 7-10 [Bond, U, T. Yario and J. A. Steitz]

'Multiple processing-defective mutations in a mammalian histone pre-mRNA are suppressed by compensatory changes in U7 RNA both in vivo and in vitro', Genes and Dev., 5 (1991), 1709-1722 [Bond, U, T. Yario, and J. A. Steitz]

'Heat shock levels in brain and other tissues after hyperthermia and transient ischemia', J. Neurochem., 54, 2 (1990), 451-458 [T. S. Nowak Jr, U. Bond and M. J. Schlesinger]

'Developmental Expression Of Ubiquitin Genes In Posterior Silk Gland Of Bombyx-Mori', Journal of Cell Biology, 111, 5 (1990), [Ichimura S, Mita K, Nenol M, James T C, and Bond U. ]

'Analysis of Pre-mRNAs in heat shocked Hela cells allows identification of the upstream termination site of human polymerase I transcription', Mol. Cell. Biol., 9 (1989), 2500-12 [K. Parker and U. Bond]

'Molecular events in avian cells stressed by heat shock and arsenite. In Stress Induced Proteins', J. Cellular Biochemistry(1989), 137-148 [M. J. Schlesinger, N. C. Collier, N. Agell and U. Bond]

'In vitro proteolytic processing of a di-ubiquitin and a truncated di-biquitin from in vitro generated mRNAs', Proc. Natl. Acad. Sci., 85 (1988), 3693-97 [N. Agell, U. Bond, and M.J. Schlesinger]

'Heat shock but not other stress inducers leads to the disruption of a sub-set of snRNPS and inhibition of in vitro splicing in HeLa cells', EMBO J., 7 (1988), 3509-3518 [U. Bond]

'Ubiquitin in stressed chicken embryo fibroblasts', J. Biol. Chem, 263 (1988), 2384-2388 [U. Bond, N. Agell, A.L. Haas, K. Redmen, and M.J. Schlesinger]

'Differential effects of stress on pre-messenger RNA processing in HeLa cells', J. Cell. Biochem, 12 (1988), 267-269 [Steitz, J. and U. Bond]

'Events in heat-shocked avian fibroblasts', J. Cell. Biochem, 12 (1988), 1-4 [Schlesinger M.J., Collier N and U. Bond ]

'Heat Shock Proteins and Development', Adv. Genetics., 24 (1987), 1-29 [U. Bond and M.J. Schlesinger]

'Ubiquitin Genes', Oxford Surveys on Eukaryotic Genes, 4 (1987), 77-91 [M.J. Schlesinger and U. Bond]

'The chicken ubiquitin gene contains a heat shock promoter and expresses an unstable mRNA in heat shocked cells', Mol. Cell Biol, 12 (1986), 4602-4610 [U. Bond and M.J. Schlesinger]

'Characterization of a supercoil-dependent S1 sensitive site 5' to the Drosophilamelanogaster hsp 26 gene', Nuc. Acids Res., 14 (1986), 9425-9444 [E. Siegfried, G.H. Thomas, U.M. Bond and S.C.R. Elgin]

'Ubiquitin is a heat shock protein in chicken embryo fibroblasts', Mol. Cell. Biol., 5 (1985), 949-956 [U. Bond and M.J. Schlesinger]

'Xenopus egg coat proteins. II. Characterization of messenger RNAs of the oviduct and cloning of estradiol inducible sequences', Comp. Biochem. Physiol., 80 (1985), 89-97 [T.C. James, C.A. Maack, U.M. Bond, J.C. Champion and J.R. Tata]

'The slow kinetic transients of Arylsulphatase A.', Biochem. J., 201 (1982), 345-53 [C. O'Fagain, U. Bond, B.A. Orsi, and T.J. Mantle]

'Construction and partial characterization of a recombinant DNA probe for locust vitellogenin messenger RNA', Biochem. J., 205 (1982), 521-28 [T.C. James, U.M. Bond, C.A. Maack, S.W. Applebaum, and J.R. Tata]

'Evolutionary conservation of vitellogenin genes', DNA, 1 (1982), 345-53 [T.C. James, U.M. Bond, C.A. Maack, S.W. Applebaum, and J.R. Tata]

'Impact of unique lager-specific genes on phenotypes in Saccharomyces pastorianus. ' , YEAST, International Congress on Yeast genetics and Molecular Biology, Levico Therme, Italy (2015), [Bond, U., Monerawela, C., and I. Sugre. (2015)

'Brewing yeasts possess dynamic genomes that undergo rearrangements and chromosome loss in response to stress.' , YEAST, International Congress on Yeast genetics and Molecular Biology, Serrento Italy (2007), [U. Bond, J. Usher and T.C. James ]

'The active response to stress.' , A New Era of Opportunity, European Brewery Monograph, Proceedings of the European Brewery Convention Symposium, Nutfield, U.K., (1999), [Donnelly, D., P. Brosnan, and U. Bond. ]

'Stress responses in brewing yeasts ' , Journal of the Institute of Brewing, 2nd Technical Meeting of the European Brewery Convention Brewing Science Group , Edinburgh, Scotland (1998), [Donnelly, D.; Brosnan, P., U. Bond ]

'Proteolytic processing of polyubiquitin' , polyubiquitin J. Cell Biology, (1987), [Agell, N., Bond. U and S.J Schlesinger ]

'Hypersensitivity sites in Hsp26 Promoter' , Genetics, (1986), [Thomas, G.H., Siegfried, E., Bond. U, and S. Elgin. ]

'Supercoil-dependent s1-nuclease sensitive sites in the drosophila locus-67B199 ' , Journal of Cell Biology., (1986), [Siegfried, E., Bond, U., Elgin, SCR.]

'Vitellogenin coding sequences in insects are conserved ' , Journal of Cellular Biochemistry, (1982), [James T C, Maack C C, Bond U, et al ]