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Current Papers

Rolfe RA, Shea CA, Murphy P. Geometric analysis of chondrogenic self organisation of embryonic limb bud cells in micromass culture. Cell Tissue Res. 2022 Jan 6.

Peterson BE, Rolfe RA, Kunselman A, Murphy P, Szczesny SE. Mechanical Stimulation via Muscle Activity is Necessary for the Maturation of Tendon Multiscale Mechanics During Embryonic Development. Front Cell Dev Biol. 2021 Sep 3;9:725563.

Shea CA, Murphy P. The Primary Cilium on Cells of Developing Skeletal Rudiments; Distribution, Characteristics and Response to Mechanical Stimulation.  Front Cell Dev Biol. 2021 Aug 20;9:725018.

Rolfe, RA., Scanlon O’Callaghan, D. Murphy P. Joint development recovery on resumption of embryonic movement following paralysis. Disease Models and Mechanisms, 2021 Mar 26;14(4).

Shea Claire.A., Rolfe Rebecca.A., McNeill H., AND Murphy Paula., Localization of YAP activity in developing skeletal rudiments is responsive to mechanical stimulation" Developmental Dynamics , 2019, Journal Article.

V Sotiriou, Rebecca A Rolfe, Paula Murphy, Niamh C Nowlan, Effects of abnormal muscle forces on prenatal joint morphogenesis in mice Journal of Orthopaedic Research, 2019, Journal Article, PUBLISHED

Mohammadkhah Melika, Murphy Paula, Simms CK.,Collagen fibril organization in chicken and porcine skeletal muscle perimysium under applied tension and compression Journal of the Mechanical Behavior of Biomedical Materials, 77, 2018, p734 - 744, Journal Article

Pratik Narendra Pratap Singh, Claire Shea, Shashank Kumar Sonker, Rebecca Rolfe, Ayan Ray, Sandeep Kumar, Pankaj Gupta, Paula Murphy, Amitabha Bandyopadhyay, Precise spatial restriction of BMP signaling in developing joints is perturbed upon loss of embryo movement Development, 145, (5), 2018, pdev153460

Rolfe Rebecca A, Shea Claire A, Singh PNP, Bandyopadhyay A, Murphy Paula, Investigating the mechanistic basis of biomechanical input controlling skeletal development: exploring the interplay with Wnt signalling at the joint Philisophical Transactions of the Royal society, 2018, Journal Article

Melika Mohammadkhah, Ciaran K Simms, Paula Murphy. Visualisation of Collagen in fixed skeletal muscle tissue using fluorescently tagged Collagen binding protein CNA35 Journal of the Mechanical Behavior of Biomedical Materials Volume 66, February 2017, Pages 37–44

Anurati Saha, Rebecca Rolfe, Simon Carroll, Daniel J Kelly, Paula Murphy Chondrogenesis of embryonic limb bud cells in micromass culture progresses rapidly to hypertrophy and is modulated by hydrostatic pressure  Cell and Tissue Research, 2016  DOI: 10.1007/s00441-016-2512-9

Melika Mohammadkhah, Paula Murphy, Ciaran K Simms The in vitro passive elastic response of chicken pectoralis muscle to applied tensile and compressive deformation Journal of the mechanical behavior of biomedical materials Volume 62, September 2016, Pages 468–480

Hayley Beaton, Darrell Andrews, Martin Parsons, Mary Murphy, Andrew Gaffney, David Kavanagh, Gareth J McKay, Alexander P Maxwell, Cormac T Taylor, Eoin P Cummins, Catherine Godson, Debra F Higgins, Paula Murphy, John Crean  Wnt6 regulates epithelial cell differentiation and is dysregulated in renal fibrosis American Journal of Physiology-Renal Physiology 1 July 2016 Vol. 311 no. 1, F35-F45 DOI: 10.1152/ajprenal.00136.2016

Danielle Mc Laughlin, Paula Murphy, Prem Puri  Notochord manipulation does not impact oesophageal and tracheal formation from isolated foregut in 3D explant culture Pediatric surgery international January 2016, Volume 32, Issue 1, pp 29–35 DOI: 10.1007/s00383-015-3809-6

CA Shea, RA Rolfe, P Murphy The importance of foetal movement for co-ordinated cartilage and bone development in utero Bone and Joint Research 3 July 2015 DOI: 10.1302/2046-3758.47.2000387

Rebecca A Rolfe, Elaine M Kenny, Paul Cormican, Paula Murphy Transcriptome analysis of the mouse E14. 5 (TS23) developing humerus and differential expression in muscle-less mutant embryos lacking mechanical stimulation Genomics data Volume 2, December 2014, Pages 32–36

Danielle Mc Laughlin, Paula Murphy, Prem Puri  Altered Tbx1 gene expression is associated with abnormal oesophageal development in the adriamycin mouse model of oesophageal atresia/tracheo-oesophageal fistula  Pediatric surgery international  February 2014, Volume 30, Issue 2, pp 143–149 doi:10.1007/s00383-013-3455-9

Rebecca A Rolfe, Niamh C Nowlan, Elaine M Kenny, Paul Cormican, Derek W Morris, Patrick J Prendergast, Daniel Kelly, Paula Murphy  Identification of mechanosensitive genes during skeletal development: alteration of genes associated with cytoskeletal rearrangement and cell signalling pathways BMC Genomics 20 January 2014 DOI: 10.1186/1471-2164-15-48

Hideaki Sato, Piotr Hajduk, Shigeyuki Furuta, Munechika Wakisaka, Paula Murphy, Prem Puri, Hiroaki Kitagawa Effect of abnormal notochord delamination on hindgut development in the Adriamycin mouse model Pediatric surgery international November 2013, Volume 29, Issue 11, pp 1209–1216 doi:10.1007/s00383-013-3386-5