Cellular and Molecular Methodologies
Researchers use a range of cellular and molecular approaches to investigate functioning of the nervous system. These include:
Electrophysiology
- In vivo and in vitro analysis of synaptic plasticity (LTP, LTD, PPF)
- Single cell recording
- Patch clamp
- Neuronal ensemble recording with multielectrode arrays in the freely-moving animal
- Transcranial direct current stimulation
Genetic Manipulation
- Transgenic and knockout mice
- Drosophila-based models
- siRNA and viral gene delivery
Cell culture systems
- Primary cultures of neurons and glia
- Primary T cell cultures
- Endothelial cell cultures
- Stem cell cultures
Analyses include: |
Techniques include: |
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