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Dr. Kathy Gately
Clinical Senior Lecturer, Clinical Medicine

Biography

Dr. Kathy Gately graduated with a BSc from University College Dublin and a PhD from the Department of Biochemistry, National University of Ireland Galway in 2000. During her PhD she spent six months at the University of California Los Angeles. She then worked as a postdoctoral fellow in the Dept. of Haematology where she carried out research on the novel targeted agent Imatinib in CML patients. In 2004, Dr. Gately was appointed as a Clinical Lecturer with Prof. Ken O'Byrne in the Dept. of Clinical Medicine. She was instrumental in the establishment of the Lung Cancer Biobank which supports research and clinical trials within the Translational Oncology Research Group (TORG).The main focus of Dr. Gately's research group is (i) the identification of novel prognostic/predictive biomarkers and therapeutic targets to improve treatment options for patients with cancer (ii) elucidating mechanisms of resistance to targeted therapies, in particular PI3K and EGFR inhibitors (iii) the role of the liquid biopsy in cancer diagnosis and treatment. Dr. Gately delivers lectures to undergraduate students in Molecular Medicine as well as the MSc in Molecular Medicine and Translational Oncology. She is editor of a recent book entitled: "Lung Cancer: A Comprehensive Review" Nova Publishers 2013. Dr. Gately is currently leading a research collaboration with Inflection Biosciences Ltd, an Irish company developing targeted small molecule treatments for cancer. The research examines the effectiveness of a panel of the company's targeted PIM kinase inhibitors in the treatment of thoracic malignancy. In particular, solid tumours that have become resistant to other forms of treatment. This research is supported in part by an Innovation Partnership Program award from Enterprise Ireland (EI).

Publications and Further Research Outputs

Peer-Reviewed Publications

LEWIS, F., WARD, M. P., SAADEH, F. A., O'GORMAN, C., MAGUIRE, P. J., BEIRNE, J. P., KAMRAN, W., IBRAHIM, E., NORRIS, L., KELLY, T., HURLEY, S., HENDERSON, B., KANJUGA, M., O'DRISCOLL, L., GATELY, K., ONER, E., SAINI, V. M., CADOO, K., MARTIN, C., O'LEARY, J. J. & O'TOOLE, S. A., A pilot study evaluating the feasibility of enriching and detecting circulating tumour cells from peripheral and ovarian veins in rare epithelial ovarian carcinomas, European Journal of Surgical Oncology, 2025 Journal Article, 2025

M Saini, Volga, Oner, Ezgi, Ward, Mark P., Hurley, Sinead, Henderson, Brian David, Lewis, Faye, Finn, Stephen P., Fitzmaurice, Gerard J., O'Leary, John J., O'Toole, Sharon, O'Driscoll, Lorraine, Gately, Kathy, A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer, Molecular Oncology, 2024 Journal Article, 2024 DOI

Richards, Cathy E. and Elamin, Yasir Y. and Carr, Aoife and Gately, Kathy and Rafee, Shereen and Cremona, Mattia and Hanrahan, Emer and Smyth, Robert and Ryan, Daniel and Morgan, Ross K. and Kennedy, Susan and Hudson, Lance and Fay, Joanna and O†Byrne, Kenneth and Hennessy, Bryan T. and Toomey, Sinead, Protein Tyrosine Phosphatase Non-Receptor 11 (PTPN11/Shp2) as a Driver Oncogene and a Novel Therapeutic Target in Non-Small Cell Lung Cancer (NSCLC), International Journal of Molecular Sciences, 24, (13), 2023 Journal Article, 2023 DOI

Opitz, I. and Bille, A. and Dafni, U. and Nackaerts, K. and Ampollini, L. and de Perrot, M. and Brcic, L. and Nadal, E. and Syrigos, K. and Gray, S.G. and Aerts, J. and Curioni-Fontecedro, A. and RÃŒschoff, J.H. and Monkhorst, K. and Weynand, B. and Silini, E.M. and Bavaghar-Zaeimi, F. and Jakopovic, M. and Llatjos, R. and Tsimpoukis, S. and Finn, S.P. and von der ThÃŒsen, J. and Marti, N. and Dimopoulou, G. and Kammler, R. and Peters, S. and Stahel, R.A. and Falcoz, P.-E. and Brunelli, A. and Baas, P. and Hiltbrunner, A. and Kammler, R. and Ruepp, B. and Tsourti, Z. and Zygoura, P. and Vervita, K. and Andriakopoulou, C. and Stavrou, A. and Haberecker, M. and Dettwiler, S. and Prutek, F. and Mittmann, C. and Vrugt, B. and Friess, M. and Matter, A. and Spichiger-HÀusermann, C. and Kirschner, M.B. and Felley-Bosco, E. and Verbeken, E. and Nafteux, P. and Moons, J. and Peeters, L. and Tiseo, M. and Gnetti, L. and Carbognani, P. and Samarzija, M. and Seiwerth, S. and Cardenal, F. and Lorente, S. and Vamvakaris, I. and Boura, P. and Nur, M.M. and Baird, A.-M. and Barr, M.P. and Cuffe, S. and Gately, K. and ThÃŒsen, J.V.D. and Passani, S., European Epidemiology of Pleural Mesotheliomaâ€"Real-Life Data From a Joint Analysis of the Mesoscape Database of the European Thoracic Oncology Platform and the European Society of Thoracic Surgery Mesothelioma Database, Journal of Thoracic Oncology, 18, (9), 2023, p1233-1247 Journal Article, 2023 DOI

Jan H. Rüschoff, Martina Haberecker, Zoi Tsourti, Kristiaan Nackaerts, Marc de Perrot, Luka Br"i", Ernest Nadal, Sotirios Tsimpoukis, Steven G. Gray, Luca Ampollini, Joachim G.J.V. Aerts, Emanuela Felley"Bosco, Michaela B. Kirschner, Kim Monkhorst, Birgit Weynand, Fatemeh Bavaghar-Zaeimi, Miroslav Samaržija, Roger Llatjos, Stephen P. Finn, Enrico Maria Silini, Jan H. von der Thüsen, Nesa Marti, Karerina Vervita, Roswitha Kammler, Solange Peters, Rolf A. Stahel, Paul Baas, Isabelle Opitz, Rolf A. Stahel, Anita Hiltbrunner, Rosita Kammler, Nesa Marti, Patrick Vagenknecht, Barbara Ruepp, Urania Dafni, Zoi Tsourti, Panagiota Zygoura, Katerina Vervita, Georgia Dimopoulou, Charitini Andriakopoulou, Androniki Stavrou, Jan H. Rüschoff, Martina Haberecker, Susanne Dettwiler, Fabiola Prutek, Christiane Mittmann, Isabelle Opitz, Paul Baas, Isabelle Opitz, Bart Vrugt, Martina Friess, Alessandra Matter, Chloé Spichiger-Häusermann, Paul Baas, Eric Verbeken, Birgit Weyenand, Liesbet M. Peeters, Marcello Tiseo, Enrico Maria Silini, Luigi Ventura, Letizia Gnetti, Paolo Carbognani, Fatemeh B. Zaeimi, Sven Seiwerth, Marko Jakopovi", Enriqueta Felip, Susana Lorente, Konstantinos Syrigos, Ioannis Vamvakaris, Paraskevi Boura, Steven G. Gray, Mutaz Mohammed Nur, Anne"Marie Baird, Nesa Marti, Sinéad Cuffe, Kathy Gately, Joachim G.J.V. Aerts, Expression of phosphorylated ribosomal protein S6 in mesothelioma patients - correlation with clinico-pathological characteristics and outcome: results from the European Thoracic Oncology Platform (ETOP) Mesoscape project, Modern Pathology, 35, (12), 2022, p1888 - 1899, p1888-1899 Journal Article, 2022 DOI

Bracken-Clarke D, Kapoor D, Baird AM, Buchanan PJ, Gately K, Cuffe S, Finn SP., Vaping and lung cancer - A review of current data and recommendations., Lung cancer (Amsterdam, Netherlands), 153, 2021, p11-20 Journal Article, 2021 DOI

Moore, G.; Lightner, C.; Elbai, S.; Brady, L.; Nicholson, S.; Ryan, R.; O'Sullivan, K.E.; O'Byrne, K.J.; Blanco-Aparicio, C.; Cuffe, S.; O'Neill, M.; Heavey, S.; Finn, S.P.; Gately, K. , Co-Targeting PIM Kinase and PI3K/mTOR in NSCLC, Cancers, 13, (9), 2021, p2139- Journal Article, 2021 URL

Moore, Gillian and Lightner, Clara and Elbai, Samira and Brady, Lauren and Nicholson, Siobhan and Ryan, Ronan and O†Sullivan, Katie E. and O†Byrne, Kenneth J. and Blanco-Aparicio, Carmen and Cuffe, Sinead and O†Neill, Michael and Heavey, Susan and Finn, Stephen P. and Gately, Kathy, Co-targeting PIM kinase and PI3K/mTOR in NSCLC, Cancers, 13, (9), 2021 Journal Article, 2021 DOI

Collins, Denis M. and Madden, Stephen F. and Gaynor, Nicola and AlSultan, Dalal and Le Gal, Marion and Eustace, Alex J. and Gately, Kathy A. and Hughes, Clare and Davies, Anthony M. and Mahgoub, Thamir and Ballot, Jo and Toomey, Sinead and O'Connor, Darran P. and Gallagher, William M. and Holmes, Frankie A. and Espina, Virginia and Liotta, Lance and Hennessy, Bryan T. and O'Byrne, Kenneth J. and Hasmann, Max and Bossenmaier, Birgit and O'Donovan, Norma and Crown, John, Effects of HER family-targeting tyrosine kinase inhibitors on antibody-dependent cell-mediated cytotoxicity in HER2-expressing breast cancer, Clinical Cancer Research, 27, (3), 2021, p807 â€" 818 Journal Article, 2021 DOI

Luszczak S, Kumar C, Sathyadevan VK, Simpson BS, Gately KA, Whitaker HC, Heavey S., PIM kinase inhibition: co-targeted therapeutic approaches in prostate cancer., Signal Transduct Target Ther., 5, (7), 2020 Journal Article, 2020 DOI

Malone T, Schäfer L, Simon N, Heavey S, Cuffe S, Finn S, Moore G, Gately K., Current perspectives on targeting PIM kinases to overcome mechanisms of drug resistance and immune evasion in cancer., Pharmacology and Therapeutics, 207, 2020 Journal Article, 2020 DOI

Thunnissen E, Kerr KM, Dafni U, Bubendorf L, Finn SP, Soltermann A, Biernat W, Cheney R, Verbeken E, Warth A, Marchetti A, Speel EM, Pokharel S, Quinn AM, Monkhorst K, Navarro A, Madsen LB, Tsourti Z, Geiger T, Kammler R, Peters S, Stahel RA; European Thoracic Oncology Platform Lungscape Consortium., Programmed death-ligand 1 expression influenced by tissue sample size. Scoring based on tissue microarrays' and cross-validation with resections, in patients with, stage I-III, non-small cell lung carcinoma of the European Thoracic Oncology Platform Lungscape cohort., Modern Pathology, 33, (5), 2020, p792 - 801 Journal Article, 2020

Toomey S, Carr A, Mezynski MJ, Elamin Y, Rafee S, Cremona M, Morgan C, Madden S, Abdul-Jalil KI, Gately K, Farrelly A, Kay EW, Kennedy S, O'Byrne K, Grogan L, Breathnach O, Morris PG, Eustace AJ, Fay J, Cummins R, O'Grady A, Kalachand R, O'Donovan N, Kelleher F, O'Reilly A, Doherty M, Crown J, Hennessy BT, Identification and clinical impact of potentially actionable somatic oncogenic mutations in solid tumor samples., Journal of Translational Medicine, 18, (1), 2020, p[1-99] Journal Article, 2020 DOI TARA - Full Text

Gaule P, Mukherjee N, Corkery B, Eustace AJ, Gately K, Roche S, O'Connor R, O'Byrne KJ, Walsh N, Duffy MJ, Crown J, O'Donovan N., Dasatinib Treatment Increases Sensitivity to c-Met Inhibition in Triple-Negative Breast Cancer Cells., Cancers, 11, (4), 2019 Journal Article, 2019 DOI

Ryan, S.-L. and Beard, S. and Barr, M.P. and Umezawa, K. and Heavey, S. and Godwin, P. and Gray, S.G. and Cormican, D. and Finn, S.P. and Gately, K.A. and Davies, A.M. and Thompson, E.W. and Richard, D.J. and O'Byrne, K.J. and Adams, M.N. and Baird, A.-M., Targeting NF-KB-mediated inflammatory pathways in cisplatin-resistant NSCLC, Lung Cancer, 135, 2019, p217-227 Journal Article, 2019 DOI

Heavey S, Dowling P, Moore G, Barr MP, Kelly N, Maher SG, Cuffe S, Finn SP, O'Byrne KJ, Gately K., Development and characterisation of a panel of phosphatidylinositide 3-kinase - mammalian target of rapamycin inhibitor resistant lung cancer cell lines., Scientific Reports, 8, (1), 2018, p1652- Journal Article, 2018 DOI TARA - Full Text

Kerr KM, Dafni U, Schulze K, Thunnissen E, Bubendorf L, Hager H, Finn S, Biernat W, Vliegen L, Losa JH, Marchetti A, Cheney R, Warth A, Speel EJ, Blackhall F, Monkhorst K, Jantus Lewintre E, Tischler V, Clark C, Bertran-Alamillo J, Meldgaard P, Gately K, Wrona A, Vandenberghe P, Felip E, De Luca G, Savic S, Muley T, Smit EF, Dingemans AC, Priest L, Baas P, Camps C, Weder W, Polydoropoulou V, Geiger TR, Kammler R, Sumiyoshi T, Molina MA, Shames DS, Stahel RA, Peters S, ETOP Lungscape Consortium., Prevalence and clinical association of gene mutations through multiplex mutation testing in patients with NSCLC: results from the ETOP Lungscape Project., Annals of oncology : official journal of the European Society for Medical Oncology, 29, (1), 2018, p200-208 Journal Article, 2018 DOI

Collins, D.M. and Gately, K. and Hughes, C. and Edwards, C. and Davies, A. and Madden, S.F. and O'Byrne, K.J. and O'Donovan, N. and Crown, J., Tyrosine kinase inhibitors as modulators of trastuzumab-mediated antibody-dependent cell-mediated cytotoxicity in breast cancer cell lines, Cellular Immunology, 319, 2017, p35-42 Journal Article, 2017 DOI

Hutchinson RA, Coleman HG, Gately K, Young V, Nicholson S, Cummins R, Kay E, Hynes SO, Dunne PD, Senevirathne S, Hamilton PW, McArt DG, Longley DB, IHC-based subcellular quantification provides new insights into prognostic relevance of FLIP and procaspase-8 in non-small-cell lung cancer, Cell Death Discovery, 14, (3), 2017, p17050- Journal Article, 2017

Adams, M.N. and Burgess, J.T. and He, Y. and Gately, K. and Snell, C. and Zhang, S.-D. and Hooper, J.D. and Richard, D.J. and O'Byrne, K.J., Expression of CDCA3 Is a Prognostic Biomarker and Potential Therapeutic Target in Nonâ€"Small Cell Lung Cancer, Journal of Thoracic Oncology, 12, (7), 2017, p1071-1084 Journal Article, 2017 DOI

O'Byrne, K., Barr, M.P., Urquhart, A., Ryan, S.-L., Gray, S.G., Davies, A., Richard, D., Gately, K., Baird, A.-M., 67P Investigation of the interaction between non-small cell lung cancer cells and immortalised normal bronchial epithelial cells, Journal of Thoracic Oncology, 11, (4), 2016, pS83-S84 Journal Article, 2016 DOI

Cathcart M.-C, Useckaite Z, Drakeford C, Semik V, Lysaght J, Gately K, O'Byrne K.J, Pidgeon G.P, Anti-cancer effects of baicalein in non-small cell lung cancer in-vitro and in-vivo, BMC Cancer, 16, (1), 2016, p707- Journal Article, 2016 DOI URL TARA - Full Text

O'Byrne, K., Ryan, S.-L., Heavey, S., Umezawa, K., Barr, M.P., Gray, S.G., Davies, A., Richard, D., Gately, K., Baird, A.-M., 68P Inflammatory meditated mechanisms of cisplatin resistance in non-small cell lung cancer, Journal of Thoracic Oncology, 11, (4), 2016, pS84 Journal Article, 2016 DOI

Hallinan N, Finn S, Cuffe S, Rafee S, O'Byrne K, Gately K, Targeting the fibroblast growth factor receptor family in cancer, Cancer Treatment Reviews, 46, 2016, p51 - 62 Journal Article, 2016 DOI URL

Burgess J.T, Bolderson E, Adams M.N, Baird A.-M, Zhang S.-D, Gately K.A, Umezawa K, O'Byrne K.J, Richard D.J, Activation and cleavage of SASH1 by caspase-3 mediates an apoptotic response, Cell Death and Disease, 7, (11), 2016, pe2469- Journal Article, 2016 TARA - Full Text DOI URL

Vlajnic, T. and Brady, L. and Casey, O. and Gately, K. and Barr, M.P. and Cuffe, S. and Bubendorf, L. and Finn, S., 26P Characteristics of circulating tumor cells (CTCs) in patients with lung cancer, Journal of Thoracic Oncology, 11, (4), 2016, pS66 Journal Article, 2016 DOI

Heavey S, Cuffe S, Finn S, Young V, Ryan R, Nicholson S, Leonard N, McVeigh N, Barr M, O'Byrne K, Gately K, In pursuit of synergy: An investigation of the PI3K/mTOR/MEK co-targeted inhibition strategy in NSCLC, Oncotarget, 7, (48), 2016, p79526 - 79543 Journal Article, 2016 URL DOI TARA - Full Text

Elamin YY et al, Thymidine phosphorylase in cancer; enemy or friend?, Cancer Microenvironment, 9, (1), 2015, p33 - 43 Journal Article, 2015

Barr, M.P., Gray, S.G., Gately, K., (...), Pidgeon, G.P., O'Byrne, K.J., Vascular endothelial growth factor is an autocrine growth factor, signaling through neuropilin-1 in non-small cell lung cancer, Molecular Cancer, 14, (1), 2015, p45- Journal Article, 2015 DOI TARA - Full Text

O'Callaghan DS, Tumour islet Foxp3+ T-cell infiltration predicts poor outcome in nonsmall cell lung cancer., European Respiratory Journal, 46, (6), 2015, p1762 - 1772 Journal Article, 2015 DOI

Dowling, Paul and Henry, Michael and Meleady, Paula and Clarke, Colin and Gately, Kathy and O†Byrne, Kenneth and Connolly, Elizabeth and Lynch, Vincent and Ballot, Jo and Gullo, Giuseppe and Crown, John and Moriarty, Michael and Clynes, Martin, Metabolomic and proteomic analysis of breast cancer patient samples suggests that glutamate and 12-HETE in combination with CA15-3 may be useful biomarkers reflecting tumour burden, Metabolomics, 11, (3), 2015, p620 â€" 635 Journal Article, 2015 DOI

Cathcart MC, Gately K, Cummins R, Drakeford C, Kay EW, O'Byrne KJ, Pidgeon GP, Thromboxane synthase expression and correlation with VEGF and angiogenesis in non-small cell lung cancer., Biochimica et biophysica acta, 1842, (5), 2014, p747-55 Journal Article, 2014 DOI

Heavey S, O'Byrne KJ, Gately K, Strategies for co-targeting the PI3K/AKT/mTOR pathway in NSCLC., Cancer treatment reviews, 40, (3), 2014, p445-56 Journal Article, 2014 DOI

Peters S, Weder W, Dafni U, Kerr KM, Bubendorf L, Meldgaard P, O'Byrne KJ, Wrona A, Vansteenkiste J, Felip E, Marchetti A, Savic S, Lu S, Smit E, Dingemans AM, Blackhall FH, Baas P, Camps C, Rosell R, Stahel RA, Lungscape: resected non-small-cell lung cancer outcome by clinical and pathological parameters., Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 9, (11), 2014, p1675-84 Journal Article, 2014 DOI

Heavey S, Godwin P, Baird AM, Barr MP, Umezawa K, Cuffe S, Finn SP, O'Byrne KJ, Gately K, Strategic targeting of the PI3K-NF"B axis in cisplatin-resistant NSCLC., Cancer biology & therapy, 15, (10), 2014, p1367-77 Journal Article, 2014 DOI

Barr M, Souan L, MacGabhann P, Muller J, Al-Ashhab M, Jasser M, Hamza K, Al-Hassoon S, Kuhn U, Infante D, Lawlor D, Kately K, Amireh E, O'Byrne K, Sughayer MA., The establishment of an ISO compliant cancer biobank for Jordan and its neighboring countries through knowledge transfer and training., Biopreservation and biobanking, 12, (1), 2014, p3-12 Journal Article, 2014 TARA - Full Text DOI

Shikhrakab H, Elamin YY, O'Brien C, Gately K, Finn S, O'Byrne K, Osman N, Epidermal growth factor receptor (EGFR) mutation testing, from bench to practice: a single institute experience., Irish medical journal, 107, (7), 2014, p201-4 Journal Article, 2014

Al-Alao BS, Gately K, Nicholson S, McGovern E, Young VK, O'Byrne KJ, Prognostic impact of vascular and lymphovascular invasion in early lung cancer., Asian cardiovascular & thoracic annals, 22, (1), 2014, p55-64 Journal Article, 2014 DOI

Gately K, Forde L, Cuffe S, Cummins R, Kay EW, Feuerhake F, O'Byrne KJ, High coexpression of both EGFR and IGF1R correlates with poor patient prognosis in resected non-small-cell lung cancer., Clinical lung cancer, 15, (1), 2014, p58-66 Journal Article, 2014 DOI

Dowling P, Pollard D, Larkin A, Henry M, Meleady P, Gately K, O'Byrne K, Barr MP, Lynch V, Ballot J, Crown J, Moriarty M, O'Brien E, Morgan R, Clynes M, Abnormal levels of heterogeneous nuclear ribonucleoprotein A2B1 (hnRNPA2B1) in tumour tissue and blood samples from patients diagnosed with lung cancer., Molecular bioSystems, 2014 Journal Article, 2014 DOI

Yuen HF, Gunasekharan VK, Chan KK, Zhang SD, Platt-Higgins A, Gately K, O'Byrne K, Fennell DA, Johnston PG, Rudland PS, El-Tanani M, RanGTPase: a candidate for Myc-mediated cancer progression., Journal of the National Cancer Institute, 105, (7), 2013, p475-88 Journal Article, 2013

Riley JS, Hutchinson R, McArt DG, Crawford N, Holohan C, Paul I, Van Schaeybroeck S, Salto-Tellez M, Johnston PG, Fennell DA, Gately K, O'Byrne K, Cummins R, Kay E, Hamilton P, Stasik I, Longley DB, Prognostic and therapeutic relevance of FLIP and procaspase-8 overexpression in non-small cell lung cancer., Cell death & disease, 4, 2013, pe951 Journal Article, 2013 DOI

Rani S, Gately K, Crown J, O'Byrne K, O'Driscoll L, Global analysis of serum microRNAs as potential biomarkers for lung adenocarcinoma., Cancer Biology & Therapy, 14, (12), 2013, p1104 - 1112 Journal Article, 2013 DOI TARA - Full Text URL

Al-Alao BS, O'Callaghan DS, Gately K, Nicholson S, Coate LE, O'Connell F, McGovern E, O'Byrne KJ, Young VK, Surgical resection for non-small cell lung cancer: clinical features and outcomes for a consecutive series at an Irish tertiary referral centre., Irish journal of medical science, 182, (2), 2013, p217-25 Journal Article, 2013

Godwin P, Baird AM, Heavey S, Barr MP, O'Byrne KJ, Gately K., Targeting nuclear factor-kappa B to overcome resistance to chemotherapy., Frontiers in oncology, 3, 2013, p120 Journal Article, 2013 TARA - Full Text DOI

Gately K, O'Flaherty J, Cappuzzo F, Pirker R, Kerr K, O'Byrne K, The role of the molecular footprint of EGFR in tailoring treatment decisions in NSCLC., Journal of clinical pathology, 65, (1), 2012, p1-7 Journal Article, 2012 DOI

Gately K, Al-Alao B, T Dhillon Mauri F, Cuffe S, Seckl M, O'Byrne K, Overexpression of the mammalian target of rapamycin (mTOR) and angioinvasion are poor prognostic factors in early stage NSCLC: a verification study., Lung cancer (Amsterdam, Netherlands), 75, (2), 2012, p217-22 Journal Article, 2012

Gately K, Collins I, Forde L, Al-Alao B, Young V, Gerg M, Feuerhake F, O'Byrne K, A role for IGF-1R-targeted therapies in small-cell lung cancer?, Clinical lung cancer, 12, (1), 2011, p38-42 Journal Article, 2011

Gately K, Kerr K, O'Byrne K, Design, construction, and analysis of cell line arrays and tissue microarrays for gene expression analysis., Methods in molecular biology (Clifton, N.J.), 784, 2011, p139-53 Journal Article, 2011 DOI

Cathcart MC, Gray SG, Baird AM, Boyle E, Gately K, Kay E, Cummins R, Pidgeon GP, O'Byrne KJ, Prostacyclin synthase expression and epigenetic regulation in nonsmall cell lung cancer., Cancer, 117, (22), 2011, p5121-32 Journal Article, 2011 DOI

Paul I, Savage KI, Blayney JK, Lamers E, Gately K, Kerr K, Sheaff M, Arthur K, Richard DJ, Hamilton PW, James JA, O'Byrne KJ, Harkin DP, Quinn JE, Fennell DA, PARP inhibition induces BAX/BAK-independent synthetic lethality of BRCA1-deficient non-small cell lung cancer., The Journal of pathology, 224, (4), 2011, p564-74 Journal Article, 2011 DOI

Cathcart MC, Gately K, Cummins R, Kay E, O'Byrne KJ, Pidgeon GP, Examination of thromboxane synthase as a prognostic factor and therapeutic target in non-small cell lung cancer., Molecular cancer, 10, 2011, p25 Journal Article, 2011 DOI

Pirker R, Consensus for EGFR mutation testing in non-small cell lung cancer: results from a European workshop., Journal of Thoracic Oncology, 2010 Journal Article, 2010

Field JK, Liloglou T, Niaz A, Bryan J, Gosney JR, Giles T, Brambilla C, Brambilla E, Vesin A, Timsit JF, Hainaut P, Martinet Y, Vignaud JM, Thunnissen FB, Prinsen C, Snijders PJ, Smit EF, Sozzi G, Roz L, Risch A, Becker HD, Elborn JS, Magee ND, Montuenga LM, Pajares MJ, Lozano MD, O'Byrne KJ, Harrison DJ, Niklinski J, Cassidy A, EUELC project: a multi-centre, multipurpose study to investigate early stage NSCLC, and to establish a biobank for ongoing collaboration., The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology, 34, (6), 2009, p1477-86 Journal Article, 2009 DOI

Wilson, TR, Redmond, KM, McLaughlin, KM, Crawford, N, Gately, K, O'Byrne, K, Le-Clorrenec, C, Holohan, C, Fennell, DA, Johnston, PG, Longley, DB, Procaspase 8 overexpression in non-small-cell lung cancer promotes apoptosis induced by FLIP silencing, CELL DEATH AND DIFFERENTIATION, 16, (10), 2009, p1352-1361 Journal Article, 2009 DOI

Gray, SG, Al-Sarraf, N, Baird, AM, Gately, K, McGovern, E, O'Byrne, KJ, Transcriptional regulation of IRS5/DOK4 expression in non-small-cell lung cancer cells., Clinical lung cancer, 9, (6), 2008, p367-374 Journal Article, 2008 DOI

Al-Sarraf, N., Gately, K., Lucey, J., Wilson, L., McGovern, E., Young, V., Lymph node staging by means of positron emission tomography is less accurate in non-small cell lung cancer patients with enlarged lymph nodes: Analysis of 1145 lymph nodes, Lung Cancer, 60, (1), 2008, p62-68 Journal Article, 2008

Al-Sarraf, N., Gately, K., Lucey, J., Aziz, R., Doddakula, K., Wilson, L., McGovern, E., Young, V., Clinical implication and prognostic significance of standardised uptake value of primary non-small cell lung cancer on positron emission tomography: analysis of 176 cases, European Journal of Cardio-thoracic Surgery, 34, (4), 2008, p892-897 Journal Article, 2008

Al-Sarraf, N., Gately, K., Lucey, J., Wilson, L., McGovern, E., Young, V., Mediastinal lymph node staging by means of positron emission tomography is less sensitive in elderly patients with non-small-cell lung cancer, Clinical Lung Cancer, 9, (1), 2008, p39-43 Journal Article, 2008

Al-Sarraf, N., Aziz, R., Gately, K., Lucey, J., Wilson, L., McGovern, E., Young, V., Pattern and predictors of occult mediastinal lymph node involvement in non-small cell lung cancer patients with negative mediastinal uptake on positron emission tomography, European Journal of Cardio-thoracic Surgery, 33, (1), 2008, p104-109 Journal Article, 2008

Al-Sarraf, N., Aziz, R., Doddakula, K., Gately, K., Wilson, L., McGovern, E., Young, V., Factors causing inaccurate staging of mediastinal nodal involvement in non-small cell lung cancer patients staged by positron emission tomography, Interactive Cardiovascular and Thoracic Surgery, 6, (3), 2007, p350-353 Journal Article, 2007

Doddakula, K., Al-Sarraf, N., Gately, K., Hughes, A., Tolan, M., Young, V., McGovern, E., Predictors of acute renal failure requiring renal replacement therapy post cardiac surgery in patients with preoperatively normal renal function, Interactive Cardiovascular and Thoracic Surgery, 6, (3), 2007, p314-318 Journal Article, 2007

Duggan, E., Caraher, E., Gately, K., O'Dwyer, M., McGovern, E., Kelleher, D., McManus, R., Ryan, T., Tumor necrosis factor-" and interleukin-10 gene expression in peripheral blood mononuclear cells after cardiac surgery, Critical Care Medicine, 34, (8), 2006, p2134-2139 Journal Article, 2006

S. R. McCann, K. Gately, E. Conneally and M. Lawler, Molecular response to imatinib mesylate following relapse after allogeneic SCT for CML, Blood, 101, (3), 2003, p1200-1 Journal Article, 2003 URL

Preface in, editor(s)Edward Arnold , The Development of the Radical Right in France from Boulanger to Le Pen, London, Macmillan, 2000, pp1 - 14, [Edward Arnold] Book Chapter, 2000

Gately, K., McElwaine, S., O'Connor, L., McCann, S., Hollywood, D., Cotter, T., Lawler, M., In vitro treatment of CML cells with antisense oligonucleotides against BCR-ABL; Requirement for an efficient delivery system, Blood, 96, (11 PART II), 2000 Journal Article, 2000

Non-Peer-Reviewed Publications

Kathy Gately, Co-targeting PIM and PI3K/mTOR using multikinase inhibitor AUM302 and a combination of AZD-1208 and BEZ235 in prostate cancer, Scientific Reports, 2020 Journal Article, 2020

kathy gately, Co-targeting PIM and PI3K/mTOR using multikinase inhibitor AUM302 and a combination of AZD-1208 and BEZ235 in prostate cancer, Scientific Reports, 2020 Journal Article, 2020

Kathy Gately, Co-targeting PIM and PI3K/mTOR using multikinase inhibitor AUM302 and a combination of AZD-1208 and BEZ235 in prostate cancer, Scientific Reports, 2020 Journal Article, 2020 DOI

Gaule P, Dasatinib, Cancers, 2019 Journal Article, 2019

Gately K, Advancing the treatment of non-small cell lung cancer - a combination approach, Cancer Professional, 2018 Journal Article, 2018

Kathy Gately, Lung Cancer : A Comprehensive Overview, First, New York U.S., Nova Science Publishers Inc, 2013 Book, 2013

Research Expertise

Keywords

Bioinformatics; Biological Sciences; Biology; Biomedical sciences; Biostatistical methods; Breast cancer; Cancer genetics and cell biology including metastasis; Cardiothoracic surgery; Cell Death; Cellular Biology; Clinical genetics; Clinical research, trials; Cytogenetics; Diagnostic bioimaging; Gene targeting in breast cancer; Gene therapy; Gene transcription in human cancer; Genetic/Molecular epidemiology; Genetics; Haemotology; Human genetics; Imaging Techniques; Immunoassays; Instrumentation development; Medical technology; Medicine; Molecular Biology; Molecular Genetics; Monoclonal antibodies; Natural Sciences; Quantitative and molecular genetics; Regulatory methods of gene expression; RNA processing, stability and degradation; Stem Cell Biology; Stem Cell biology and hematopoiesis; Systematic Biology; Therapeutic and Clinical oncology; Tumour immunology and immunotherapy

Recognition

Memberships

AACR

ETOP

BTOG

ESBB

IASLC

ESMO

Irish Thoracic Society (ITS)

ERS