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Selected Publications

COOPER, SARAH; KENNEDY, NICHOLAS; MOHAMED, BASHIR; Abuzakouk, Mohamed; DUNNE, JEAN; Byrne, Greg; MCDONALD, GEORGE; DAVIES, ANTHONY; EDWARDS, CONNLA; KELLY, JACINTA; FEIGHERY, CON. Immunological indicators of coeliac disease activity are not altered by long term oats challenge. Clinical and Experimental Immunology - CEI-2012-3622.R1 2012.

Robin Daly1, Gisela Vaz2, Dr. Anthony M. Davies2, Prof. Dr. Mathias O. Senge1,2, Prof. Dr. Eoin M. Scanlan1,* Synthesis and Biological Evaluation of a Library of Glycoporphyrin Compounds 10.1002/chem.201202064 Chemistry - European Journal

Verma NK, Dempsey E, Long A, Davies A, Barry SP, Fallon PG, Volkov Y, Kelleher D.
Leukocyte Function-Associated Antigen-1/Intercellular Adhesion Molecule-1 Interaction Induces a Novel Genetic Signature Resulting in T-Cells Refractory to Transforming Growth Factor-β Signalling.J Biol Chem. 2012 Jun 15.

Rietz A, Volkov Y, Davies A, Hennessy M, Spiers JP.Okadaic acid induces matrix metalloproteinase-9 expression in fibroblasts: crosstalk between protein phosphatase inhibition and β-adrenoceptor signalling. Br J Pharmacol. 2012 Jan;165(1):274-88..

Mohamed BM, Verma NK, Davies AM, McGowan A, Staunton KC, Prina-Mello A, Kelleher D, Botting CH, Causey CP, Thompson PR, Pruijn GJ, Kisin ER, Tkach AV, Shvedova AA, Volkov Y.
Citrullination of proteins: a common post-translational modification pathway induced by different nanoparticles in vitro and in vivo. Nanomedicine (Lond). 2012 May 25.

Sergeeva NN, Donnier-Marechal M, Vaz G, Davies AM, Senge MO. Synthesis and evaluation of the europium(III) and zinc(II) complexes as luminescent bioprobes in high content cell-imaging analysis. J Inorg Biochem. 2011 Dec;105(12):1589-95. Epub 2011 Sep 14.

Freeley M, O'Dowd F, Paul T, Kashanin D, Davies A, Kelleher D, Long A.L-plastin regulates polarization and migration in chemokine-stimulated human T lymphocytes. J Immunol. 2012 Jun 15;188(12):6357-70. Epub 2012 May 11.

Mohamed B.M., Verma N.K., Prina-Mello A., Williams Y., Davies A.M., Bakos G., Tormey L., Edwards C., Hanrahan J., Salvati A., Lynch I., Dawson K., Kelleher D., Volkov Y. Activation of stress-related signalling pathway in human cells upon SiO2 nanoparticles exposure as an early indicator of cytotoxicity. Journal of Nanobiotechnology 2011 Jul 29;9:29

Natalia N. Sergeeva a,b,⇑, Marion Donnier-Marechal b, Gisela M. Vaz a, Anthony M. Davies c, Mathias O. Senge. Simple but powerful: Phenanthroline-based small molecules for cellular imaging and cancer, Bioorganic & Medicinal Chemistry Letters 21 (2011) 4385–4388

Buckley ST, Medina C, Davies AM, Ehrhardt C.
Cytoskeletal re-arrangement in TGF-β1-induced alveolar epithelial-mesenchymal transition studied by atomic force microscopy and high-content analysis. Nanomedicine. 2011 Jul 12.

Mohamed BM, Verma NK, Prina-Mello A, Williams Y, Davies AM, Bakos G, Tormey L, Edwards C, Hanrahan J, Salvati A, Lynch I, Dawson K, Kelleher D, Volkov Y
Activation of stress-related signalling pathway in human cells upon SiO2 nanoparticles exposure as an early indicator of cytotoxicity. J Nanobiotechnology. 2011 Jul 29;9:29.

Maria F. O'Connor1, Arthur Hughes , Chaoxin Zheng1, Anthony Davies,
Dermot Kelleher, and Khurshid Ahmad. Annotation and Retrieval of Cell Images IDEAL June 2010.

Kozak K, Bakos G, Hoff A, Bennett E, Dunican D, Davies A, Kelleher D, Long A, Csucs G.
Workflow-based software environment for large-scale biological experiments. Biomol Screen. 2010 Aug;15(7):892-9

Verma N.K., Davies A.M., Long A., Kelleher D., Volkov Y., STAT3 knockdown by SiRNA induces apoptosis in human cutaneous T-cell lymphoma line Hut78 via downregulation of Bcl-xL, Cellular and Molecular Biology Letters, 15, (2), 2010, p342 - 355

Freeley M, Bakos G, Davies A, Kelleher D, Long A, Dunican DJ
A High-Content Analysis Toolbox Permits Dissection of Diverse Signaling Pathways for T Lymphocyte Polarization. J Biomol Screen. 2010 May 10.

Byrne AM, Foran E, Sharma R, Davies A, Mahon C, O'Sullivan J, O'Donoghue D, Kelleher D, Long A. Bile acids modulate the Golgi membrane fission process via a protein kinase C{eta} and protein kinase D-dependent pathway in colonic epithelial cells.
Carcinogenesis. 2010 Jan 21.

Williams Y, Sukhanova A, Nowostawska M, Davies AM, Mitchell S, Oleinikov V, Gun'ko Y, Nabiev I, Kelleher D, Volkov Y. Probing Cell-Type-Specific Intracellular Nanoscale Barriers Using Size-Tuned Quantum Dots.Small. 2009 Aug 14.

Abdel-Latif MM, Windle HJ, Davies A, Volkov Y, Kelleher D., A new mechanism of gastric epithelial injury induced by acid exposure: the role of Egr-1 and ERK signaling pathways., Journal of Cellular Biochemistry, 2009

Navin K. Verma, Jennifer Dourlat, Anthony M. Davies, Aideen Long, Wang-Qing Liu, Christiane Garbay, Dermot Kelleher, and Yuri Volkov. STAT3-stathmin interactions control microtubule dynamics in migrating T-cells J Biol Chem. 2009 Feb 26.

Fiona Byrnea,Adriele Prina Melloa, Aine Whelan c, Bashir M.Mohamed b, Anthony Davies b,YuriiK.Gun’koc,J.M.D.Coeya,YuriVolkov. J. High content analysis of the biocompatibility of nickel nano-wires Magn.Magn.Materj.jmmm.2009.02.035

Williams Y, Byrne S, Bashir M, Davies A, Whelan A, Gun'ko Y, Kelleher D, Volkov Y, Comparison of three cell fixation methods for high content analysis assays utilizing quantum dots.J Microsc. 2008 Oct;232(1):91-8.

Jennifer Conroy, Stephen J. Byrne, Yurii K. Gunko, Yury P. Rakovich, John F. Donegan, Anthony Davies, Dermot Kelleher, and Yuri Volkov. CdTe Nanoparticles display Tropism to Core-Histones and Histone-Rich Cell Organelles. SMLL 200800088 April 2008 J

Spiers J.P., Edwards C., Rietz A., Jan E., Mulcahy f., Hennessy M., Volkov Y., Davies A.M., Protease inhibitor-induced cardiotoxicity: direct effects on cell viability and intracellular calcium levels, Journal of the International AIDS Society, 11, 2008, p91 - 92

Mohamed BM, Feighery C, Williams Y, Davies A, Kelleher D, Volkov Y, Kelly J, Abuzakouk M. The use of Cellomics to study enterocyte cytoskeletal proteins in coeliac disease patients. Central European Journal of Biology, 3 (3):258-267

Navin K. Verma1, Eugene Dempsey1, Jennifer Conroy1, Peter Olwell1, Anthony M. Mcelligott2, Anthony M. Davies1, Dermot Kelleher1, Stefania Butini4, Giuseppe Campiani4, D. Clive Williams3, Daniela M. Zisterer3, Mark Lawler2 and Yuri Volkov1. A new microtubule-targeting compound PBOX-15 inhibits T-cell migration via post-translational modifications of tubulin. J Mol Med. 2008 Apr;86(4):4

Edward Jan,† Stephen J. Byrne,‡ Meghan Cuddihy,† Anthony M. Davies,§ Yuri Volkov,§ Yurii K. Gun’ko,‡,* and Nicholas A. Kotov†,* High-Content Screening as a Universal Tool for Fingerprinting of Cytotoxicity of Nanoparticles (ACS Nano, 2(5), 928–938, 2008)

Zheng C., Long A., Volkov Y., Davies A., Kelleher D., Ahmad K., A cross-modal system for cell migration image annotation and retrieval, Neural Networks, 1-6, 2007, p1738 - 1743

I. Nabiev, S. Mitchell, A. Davies, Y. Williams, D. Kelleher, R. Moore, Y.K. Gun’ko*, S. Byrne, Y.P. Rakovich, J.F. Donegan*, A. Sukhanova, J. Conroy, D. Cottell, N. Gaponik, A. Rogach, Y. Volkov. Nonfunctionalized Nanocrystals Can Exploit a Cell’s Active Transport Machinery Delivering Them to Specific Nuclear and Cytoplasmic Compartments NanoLetters 7(11):3452–3461, 2007.

S.J. Byrne, Y. Williams, A. Davies, S.A. Corr, A. Rakovich, Y.K. Gun’ko*, Y.R. Rakovich, J.F. Donegan*, Y.K. Volkov, “Jelly dots”: Synthesis and cytotoxicity studies of CdTe quantum dot-gelatin nanocomposites Small 3 (7): 1152–1156, 2007.

Anthony Davies etal ; A reduction to practise for siRNA screening utilising High Content Analysis (HCA) Technologies European Pharmaceutical Review issue 6 Jul 10 2012

Anthony Davies etal ; Miniaturization of Cell Based Assays Parts 1 and 2: G.I.T. Laboratory Journal Europe 7-8/2011 (Sep. 29, 2011).

ST Buckley, AM Davies, C Ehrhardt, Atomic force microscopy (AFM) and high-content analysis (HCA) - two innovative technologies for dissecting the relationship between epithelial-mesenchymal transition (EMT)-related morphological and structural alterations and cell mechanical properties, Methods Mol Biol , 784, 2011, p197-208

Anthony Davies; Assay minatuisation HCS Economy in the scale European Pharmaceutical Review (December 2010).

Anthony Davies, Anthony McElligott, Graham Pidgeon, PhD., Anthony Ryan, Ruth Foley; Cancer biology where do we go next?, European Pharmaceutical Review (February 2010).

Anthony Davies; Cellular imaging and analysis future perspectives. International Drug Discovery (Jan 2010).

Anthony Davies; High Content analysis for beginners European Pharmaceutical Review (December 2009).

Anthony Davies, Sarah Payne,Jeremy Simpson, Oscar 'Joe' Trask and Peter Simpson,High Content Analysis Roundtable article; European Pharmaceutical review (June 2009)

Anthony M Davies, Yuri Volkov, Paul J Speirs Automated Drug Discovery Development of Cardiac Cell Based Assays to Study Drug Efficacy and Toxicity” Trends in Drug Discovery (July 2008).

Anthony M Davies, Yuri Volkov, Aideen Long Dermot Kelleher; HCS setups and Workflows;BIOinform Europe sept 2008 (GIT VERLAG).

Yuri Volkov, Paul J Spiers and Dr Anthony Davies; Development of cardiac cell based assays for study of cardiac disease - in with the new by automating the old, European pharmaceutical review December 2008

Anthony Mitchell Davies Automated Workflow Optimization and Assay Development Strategies for High Content Research Facility, Trinity College Dublin" European Pharmaceutical review (November 2007).