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Dr. Edna Roche
PROFESSOR IN PAEDIATRICS, Paediatrics

Biography

Edna Roche is Professor in Paediatrics at the University of Dublin, Trinity College Dublin and a consultant paediatrician and paediatric endocrinologist at Childrens' Health Ireland (CHI) at Tallaght University Hospital. She qualified in Medicine at Trinity College where she also obtained her Doctorate. She holds a postgraduate qualification from the NUI, Membership and Fellowships from the Royal College of Physicians of Ireland, Edinburgh and the Royal College of Paediatrics and Child Health London. Dr Roche completed her clinical training in Ireland, the Middlesex Hospital and the Childrens Hospital Great Ormond Street London and in North America. She has a particular interest in Management, undertaking an MBA in Strategic management at Trinity for which she was awarded 1st Place. She has extensive academic experience and introduced many innovations and new programmes to the University. She is an enthusiastic clinical teacher encouraging her students in self-directed and life-long learning. In recognition of her teaching she was awarded the Provosts award for teaching excellence. She has supervised many postgraduate students in both clinical medicine and management and published over 50 peer reviewed papers. She is a keen researcher whose research objective is to: optimise clinical care; promote health; prevent unnecessary complications; and enhance quality of life, through collaboration nationally and internationally. Clinical research areas include Paediatric Diabetes and Endocrinology (rare syndromes, growth and development which underpin health in childhood and adult life) and Down Syndrome. Amongst her many research achievements she has developed the Irish Childhood Diabetes National Register, a major asset in diabetes care and the Down Syndrome Register. She has extensive research collaborations nationally and internationally. She is a member of a number of important research networks such as the Hvidoere International study group in diabetes and EURODIAB. She is a contributor to many professional associations at home and abroad. She was a Ministerial appointee to the National Paediatric Hospital Development Board for the new Childrens Hospital. Dr Roche is former Director or Research at Down Syndrome Ireland and a member of the Steering Group of the Down Syndrome Medical Interest Group (DSMIG) Ireland and UK. She Chairs the Nutrition Council of the Irish Heart Foundation, is a member of the Clinical Advisory Group for Obesity of the Royal College of Physicians of Ireland and is a member of the Clinical Advisory Group of the Faculty of Paediatrics, Royal College of Physicians of Ireland through which she makes a significant contribution in shaping the future of Child Health in Ireland.

Publications and Further Research Outputs

Peer-Reviewed Publications

Niamh Lagan, Dean Huggard, Fiona Mc Grane, Timothy Ronan Leahy, Orla Franklin, Edna Roche, David Webb, Aengus O'Maricaigh, Des Cox, Afif Elkuffash, Peter Greally, Joanne Balfe, Eleanor J Molloy, Multiorgan involvement and management in children with Down Syndrome, Acta Paediatrica, (1), 2020 Journal Article, 2020 DOI

Dean Huggard, Lynne Kelly, Emer Ryan, Fiona McGrane, Niamh Lagan, Edna Roche, Joanne Balfe, T. Ronan Leahy, Orla Franklin, Derek G. Doherty, Eleanor J. Molloy, Increased systemic inflammation in children with Down syndrome, Cytokine, 127, 2020, p154938 Journal Article, 2020 DOI

Feighan SM, Hughes M, Maunder K, Roche E, Gallagher L. , A profile of mental health and behaviour in Prader Willi Syndrome, J Intellect Disabil Res. , 64, (2), 2020, p158 - 169 Journal Article, 2020 DOI

Huggard D, Koay WJ, Kelly L, McGrane F, Ryan E, Lagan N, Roche E, Balfe J, Leahy TR, Franklin O, Moreno-Oliveira A, Melo AM, Doherty DG, Molloy EJ., Altered Toll-Like Receptor Signalling in Children with Down Syndrome., Mediators of inflammation, 2019, 2019, p4068734 Journal Article, 2019 DOI

Griffiths S, Loveday C, Zachariou A, Behan LA, Chandler K, Cole T, D'Arrigo S, Dieckmann A, Foster A, Gibney J, Hunter M, Milani D, Pantaleoni C, Roche E, Sherlock M, Springer A, White SM, Childhood Overgrowth Collaboration, Tatton-Brown K., EED and EZH2 constitutive variants: A study to expand the Cohen-Gibson syndrome phenotype and contrast it with Weaver syndrome., American journal of medical genetics. Part A, 179, (4), 2019, p588-594 Journal Article, 2019 DOI

Roche E, McKenna A, Ryder K, Fitzgerald H, O'Regan M, Hoey H. The Irish Childhood Diabetes National Register , The frequency of diabetic ketoacidosis at type 1 diabetes onset in a national incident cohort over a 5 year period , Pediatric Diabetes, 45th Annual Meeting of the International Society for Pediatric and Adolescent Diabetes (ISPAD), Boston, USA, Oct30-Nov 2 2019, Volume 20, (Issue S28), Wiley, 2019, pp108- Poster, 2019 DOI

Wegmann MG, Jensen RB, Thankamony A, Frystyk J, Roche E, Hoey H, Kirk J,, Increases in bioactive IGF do not parallel increases in total IGF-I during growth hormone treatment of children born SGA, J Clin Endocrinol Metab. , 2019 Journal Article, 2019 DOI

McGrane F, Roche EF, THe Adolescent with Down Syndrome in Ireland, Joint Irish Paediatric Association and Welsh Paediatric Society Annual Meeting, Clayton Hotel, Ballybrit Galway, 7- 8th December 2018, 2018 Poster, 2018

Meade C, Martin R, Crowe C, Lyons J, McCrann A, Meehan J, Hoey H, Roche E , Quality of Life and the Impact of Caring for a Child with Prader Willi Syndrome, Joint Irish Paediatric Association and Welsh Paediatric Society Annual Meeting, Clayton Hotel, Ballybrit Galway, 7- 8th December 2018, 2018 Poster, 2018

Metwally N, Macken A, O'Regan M, Fitzgerald H, McDonnell C, O'Gorman CS, Molloy E, Roche EF, Evaluation of diabetes related complications and endothelial dysfunction in adolescents with Type 1 diabetes, Horm Res Paediatr , 57th Annual ESPE Meeting , Athens, Greece , 27-29 September 2018, 90 , ( (suppl 1) ), 2018, pp216.- Meeting Abstract, 2018 DOI

McMorrow AM, Connaughton RM, Magalhães TR, McGillicuddy FC, Hughes MF, Cheishvili D, Morine MJ, Ennis S, Healy ML, Roche EF, Tremblay RE, Szyf M, Roche HM, Personalized Cardio-Metabolic Responses to an Anti-Inflammatory Nutrition Intervention in Obese Adolescents: A Randomized Controlled Crossover Trial., Molecular nutrition & food research, 2018 Journal Article, 2018 DOI

Roche EF, McGowan A, Koulouri O, Turgeon MO, Nicholas AK, Heffernan E, El-Khairi R, Abid N, Lyons G, Halsall D, Bonomi M, Persani L, Dattani MT, Gurnell M, Bernard DJ, Schoenmakers N, A novel IGSF1 mutation in a large Irish kindred highlights the need for familial screening in the IGSF1 deficiency syndrome, 89, (6), 2018, p813 - 823 Journal Article, 2018 Other DOI

McKenna A, Sandys N, Ryder K, Metwally N, Brennan A, O'Regan M, Hoey MCV, Roche EF, Single Centre Experience - Clinical Presentation and Frequency of Paediatric Diabetic Ketoacidosis (DKA) At Diagnosis over a 5-Year Period., Irish medical journal, 111, (3), 2018, p714 - 716 Journal Article, 2018

Huggard D, McGrane F, Lagan N, Roche E, Balfe J, Leahy TR, Franklin O, Moreno A, Melo AM, Doherty DG, Molloy EJ, Altered endotoxin responsiveness in healthy children with Down syndrome., BMC immunology, 2018 Journal Article, 2018 DOI TARA - Full Text

O'Riordan F, McDonnell C, Roche EF, Screening for Coeliac Disease and IgA deficiency in the Paediatric Diabetes Population, Joint Irish Paediatric Association and Welsh Paediatric Society Annual Meeting, Clayton Hotel, Ballybrit Galway, 7- 8th December 2018, 2018 Poster, 2018

Lateva M, Kassim A, Meade C, Maher R, McCrann A, Roche E, Poor weight gain in Prader Willi Syndrome - not always over-restriction consider coeliac disease, Horm Res Paediatr , 57th Annual ESPE Meeting, Athens, Greece , 27-29 September 2018, 90, ((suppl 1):), 2018, pp437- Meeting Abstract, 2018 DOI

Mahon M, Amaechi G, Slattery F, Sheridan AL, Roche EF, Fifteen-minute consultation: Polydipsia, polyuria or both., Archives of disease in childhood. Education and practice edition, 2018 Journal Article, 2018 DOI

Patterson CC, Harjutsalo V, Rosenbauer J, Neu A, Cinek O, Skrivarhaug T, Rami-Merhar B, Soltesz G, Svensson J, Parslow RC,... Roche EF, .. Green A, Trends and cyclical variation in the incidence of childhood type 1 diabetes in 26 European centres in the 25 year period 1989-2013: a multicentre prospective registration study., Diabetologia, 62, (3), 2018, p408 - 417 Journal Article, 2018 DOI

Wegmann MG, Thankamony A, Roche E, Hoey H, Kirk J, Shaikh G, Ivarsson S, Soder O, Dunger DB, Juul A, Jensen RB, The exon3-deleted growth hormone receptor gene polymorphism (d3-GHR) is associated with insulin and spontaneous growth in short SGA children (NESGAS), Growth Hormone and IGF Research, 35, 2017, p45 - 51 Journal Article, 2017 DOI

Hoey H, Lange K, Skinner TC et al Hvidoere International Study Group., Hvidoere Smiley Faces: International diabetes quality of life assessment tool for young children, Paediatric Diabetes, 2017 Journal Article, 2017 DOI URL

Nicholas, A.K., Jaleel, S., Lyons, G., Schoenmakers, E., Dattani, M.T., Crowne, E., Bernhard, B., Kirk, J., Roche, E.F., Chatterjee, V.K., Schoenmakers, N., Molecular spectrum of TSHß subunit gene defects in central hypothyroidism in the UK and Ireland, Clinical Endocrinology, 86, (3), 2017, p410-418 Journal Article, 2017 DOI Other URL

Martin R, Meade C, Mc Crann A , Roche E, Exploring the growth and nutritional status in children with Prader-Willi syndrome, Endocrine Abstracts , 45th Meeting of the British Society for Paediatric Endocrinology and Diabetes, Newcastle, UK, 22 - 24 November 201, 51 P023 , 2017 Conference Paper, 2017

Edna Roche, Anne McGowan, Olympia Koulouri et al, A novel IGSF1 mutation in a large Irish kindred highlights the need for family screening in the IGSF1 deficiency syndrome, Endocrine Abstracts (2017) 51 P060 , 45th Meeting of the British Society for Paediatric Endocrinology and Diabetes, Newcastle, UK, 22 - 24 November 201, 51, (51 P060 ), 2017 Conference Paper, 2017 DOI

Skinner TC, Lange KS, et al Hvidoere Study Group., Targets and teamwork:Understanding differences in paediatric diabetes centres treatment outcomes, Pediatric Diabetes., 2017 Journal Article, 2017 DOI URL

Ajay Thankamony Rikke Beck Jensen Susan M O'Connell Felix Day Jeremy Kirk Malcolm Donaldson Sten-A Ivarsson Olle Söder Edna Roche Hilary Hoey Ken K Ong David B Dunger Anders Juul, Adiposity in children born small for gestational age is associated with β-cell function, genetic variants for insulin resistance and response to growth hormone treatment, The Journal of clinical endocrinology and metabolism, 101, (1), 2016, p131 - 142 Journal Article, 2016 URL

Nadeem, M., Roche, E.F., Bone mineral density in short individuals; how can we interpret it?, Irish Medical Journal, 109, (8), 2016 Journal Article, 2016 URL

Roche, E.F , McKenna, A.M., Ryder, K.J., Brennan, A.A., O"Regan, M., Hoey, H.M., Is the incidence of type 1 diabetes in children and adolescents stabilising? The first 6 years of a National Register , European Journal of Pediatrics, 175, (12), 2016, p1913-1919 Journal Article, 2016 DOI

Neu, A., Lange, K., Barrett, T., Cameron, F., Dorchy, H., Hoey, H., Jarosz-Chobot, P., Mortensen, H., Robert, J.-J., Robertson, K., de Beaufort, C., Aanstoot, H.J., Åman, J., Barrett, T., de Beaufort, C., Cameron, F., Castaño, L., Castro-Correia, C., ChiarelliF, Chiari, G., Danne, T., Dorchy, H., Fisher, L.K., HoeyH, Jarosz-Chobot, P., Kaprio, E.A., Kocova, M., Lange, K., Mortensen, H.B., Neu, A., Njølstad, P.R., Palmert, M., Phillip, M., Pociot, F., Robert, J.J., Robertson, K.J., Roche, E.F., Schönle, E.J., Shalitin, S., Skinner, T., Swift, P., Urakami, T., Vanelli, M., Classifying insulin regimens - difficulties and proposal for comprehensive new definitions, Pediatric Diabetes, 16, (6), 2015, p402-406 Journal Article, 2015 DOI

Jensen, R.B., Thankamony, A., Day, F., Scott, R.A., Langenberg, C., Kirk, J., Donaldson, M., Ivarsson, S.-A., Söder, O., Roche, E., Hoey, H., Juul, A., Ong, K.K., Dunger, D.B., Genetic markers of insulin sensitivity and insulin secretion are associated with spontaneous postnatal growth and response to growth hormone treatment in short SGA children: The North European SGA Study (NESGAS), Journal of Clinical Endocrinology and Metabolism, 100, (3), 2015, pE503-E507 Journal Article, 2015 URL

B eck Jensen R, Thankamony A, Day F, Scott RA, Langenberg C, Kirk J, Donaldson M., Ivarsson SA, Soder O, Roche E, Hoey H, et al, Gnetic markers of insulin sensitivity and insulin secretion are associated wth spontaeous postnatal growth and response to growth hormone treatment in short SGA children: the North European SGA Study (NESGAS), Journal of Clinical Endocrinology and Metabolism, 100, (3), 2015, pE503 - E507 Journal Article, 2015

Nadeem M, Roche EF ("Senior"), Thyroid disorders in girls with Turner syndrome and the influence of the underlying karyotype, Irish Medical Journal, 108, (3), 2015, p93 - 94 Journal Article, 2015 URL

Lewis S, Coveney J, Roche EF, Kyriakou A, An assessment of the hypothalamic-pituitary-adrenal axis in children with prader-willi syndrome (PWS), endocrine Abstracts , 43rd Annual meeting of the British Society for Paediatric Endocrinology and Diabetes, Sheffield, UK, 25-27 November 2015, 39, (7), 2015, pp7- Meeting Abstract, 2015 URL

S. Mohamed, E.F. Roche, H.M.C.V. Hoey , High prevalence of spontaneous puberty in patients with turner syndrome in tertiary referral center in ireland, Acta Endocrinologic, XI, (1), 2015, p60 - 63 Journal Article, 2015 URL

Mohamed S, Roche EF, Hoey HM, Mode of initial presentaiton and chromosomal abnormalities in Irish patients with Turner syndrome: a single-centre expreience., Journal of Pediatric Endocrinology and Metabolism, 28, 2015, p1215 - 1218 Journal Article, 2015

Jensen RB, Thakamony A, Day F, Kirk J, Donaldson M, Ivarsson S, Soden O, Roche E, Hoey H, Juul A, Ong K, Dunger D , Genetic Markers of insulin Resistance are associated with GH Response in Short SGA Children: the North European SGA Study, Hormone Research in Paediatrics , ESPE 53rd Annual Meeting , Convention Centre Dublin, 18-20 September 2014, Volume 82 , (Supplement 1), 2014, pp42- Meeting Abstract, 2014

Nadeem M, Roche EF ("Senior"), Turner syndrome awareness of health issues, Irish Medical Journal, 107, (7), 2014, p222- Journal Article, 2014 URL TARA - Full Text

Nicholas AK, Jaleel S, Schoenmakers E, Dattani M, Roche E, Chatterjee VK, Schoenmakers N , Congenital central hypothyroidism due to a TSHB mutation with uniparental inheritance, Endocrine Abstracts , 42nd Annual meeting of the British Society for Paediatric Endocrinology and Diabetes, Winchester, UK, 12-14 November 2014, 36, (P83 ), 2014 Meeting Abstract, 2014 URL

Roche, E.F. ("Senior"), The national paediatric diabetes register and its impact on healthcare, Irish Medical Journal, 107, (7), 2014, p197 - 198 Journal Article, 2014 URL

Jensen RB, Thankamony A, O'Connell Sm, Roche EF, et al, A randomised controlled trial evaluating IGF1 titration in contras to curren GH dosing stategies in childen born small for gestatin age: the North european Small-for-Gestational-Age Study., Eur J Endocrinolo, 171, (4), 2014, p509 - 518 Journal Article, 2014 URL URL

Nadeem M, Roche EF ("Senior"), Bone Mineral Density in Turner's syndrome and the influence of pubertal development., Acta Paediatrica, 103, (1), 2014, pe38 - 42 Journal Article, 2014 URL URL

Roche EF ("Senior"), The National Paedaitric Diabetes Register and its impact on healthcare, Irish Medical Journal, 107, (7), 2014, p197 - 198 Journal Article, 2014 URL TARA - Full Text

Nadeem M, Roche EF ("Senior"), Health-related quality of life in Turner Syndrome and th influence of key features, J Pediatr Endocrinol Metab, 27, (3), 2014, p283 - 289 Journal Article, 2014

George S, Hoey HMCV, Costigan C, Murphy N, Roche EF, O'Riordan SMP , Improved Health-related Quality of life with insulin therapy in children with cystic fibrosis related diabetes: a prospective Cohort study, hormone Research in Paediatrics , ESPE 53rd Annual Meeting , convention Centre Dublin, 18-20 September 2014, 82, (supplement 1), 2014, pp103- Meeting Abstract, 2014

Roche EF, McKenna A, Ryder K, Brennan A, O'Regan M, Hoey H, The incidence of childhood type 1 diabetes in Irealnd and the National Childhood Diabetes Register., Irish Medical Journal, 107, (9), 2014, p278 - 281 Journal Article, 2014 URL TARA - Full Text

Nadeem M, Roche EF ("Senior"), Health-related quality of life in Turner syndrome and the influence of key features., Journal of Pediatric Endocrinology and Metabolism, 27, (3-4), 2014, p283-9- Journal Article, 2014 URL DOI

M Nadeem, EF Roche ("Senior"), Height in Turner syndrome: Does Growth Hormone Therapy Have Impact?, Irish Medical Journal, 107, (2), 2014, p61 - 62 Journal Article, 2014 URL TARA - Full Text

O'Connell SM, Lynch S,Coyle D, McDermott M, O'Sullivan M, Roche E, Quinn F, Cody D , The Incidence of Childhood Gonadoblastoma over 15 years in the Republic of Ireland , hormone Research in Paediatrics , ESPE 53rd Annual Meeting, , convention Centre Dublin, 18-20 September 2014, 82, (supplement 1), 2014, pp156- Meeting Abstract, 2014

Duignan A, Kennedy C, Canas-Martinez A, Gildea D, Jamaludin MA, Moore M, Meehan J, Nadeem M, Roche EF , Attitudes of parents and staff towards medical students on the paediatric wards., Irish Medical Journal, 107, (1), 2014, p26 - 28 Journal Article, 2014 TARA - Full Text

Nadeem M, Roche EF ("Senior"), Body fat distribution in Turner syndrome and the influence of puberty., Irish Medical Journal, 107, (8), 2014, p260- Journal Article, 2014 URL TARA - Full Text

Letshwiti J, O'Mullane E, Hoey H, Roche E ("Senior") , The Effect of Long term GH Therapy in Discordant Twins where one twin is born small for gestational age: A case control study, Hormone Research in Paediatrics , ESPE 53rd Annual Meeting , Convention Centre Dublin, 18-20 September 2014, 82, (Supplement 1), karger, 2014, 257 Meeting Abstract, 2014

O'Donovan C, Roche EF, Hussey J, The energy cost of playing active video games in children with obesity and children of a healthy weight, Pediatr Obes, 9, (4), 2014, p310 - 317 Journal Article, 2014

Nadeem M, Roche EF ("Senior"), Bone mineral density in Turner's syndrome, Hormone Research in Paediatircs, 9th Joint Meeting of Paediatric Endocrinology, Milan, Italy, September 2013, 80, (Supp 1), 2013, pp378- Poster, 2013

Khadr SN, Carmichael P, Holf V, Roche EF, Viner R., Study of gender identity disorder in children and adolescents., Hormone Research in Paediatircs, 9th Joint Meeting of Paediatric Endocrinology, Milan, Italy, September 2013, 80, (Supp 1), 37, 2013, pp37- Meeting Abstract, 2013

O'Donovan C, Roche EF, Hussey J, The energy cost of playing active video games in children with obesity and children of a healthy weight., Pediatric obesity, 2013 Journal Article, 2013 DOI TARA - Full Text

O'Mullane, O'Connell, Roche EF, Hoey H., How late is too late to treat with Growth Hormone? A case study., 41st Meeting of the British Society for Paediatric Endocrinology and Diabetes., Brighton, UK, November 2013, 2013 Poster, 2013

Jensen, R.B., Thankamony, A., O'Connell, S.M., Salgin, B., Kirk, J., Donaldson, M., Ivarsson, S.-A., Söder, O., Roche, E., Hoey, H., Dunger, D.B., Juul, A., Baseline IGF-I Levels Determine Insulin Secretion and Insulin Sensitivity during the First Year on Growth Hormone Therapy in Children Born Small for Gestational Age. Results from a North European Multicentre Study (NESGAS)on behalf of the NESGAS group, Hormone Research in Paediatrics, 80, (1), 2013, p38-46 Journal Article, 2013

O'Mullane E, Roche EF, Hamill C, Exploring the culture of listening amongst children's nurses in an outpatient department: A mini-ethnographic study., 41st Meeting of the British Society for Paediatric Endocrinology and Diabetes., Brighton, UK, November 2013, 2013 Poster, 2013

Nadeem M, Roche EF ("Senior"), Coeliac disease in Turner syndrome, Archives fo Disease in Childhood, 98, (8), 2013, p649 - 650 Journal Article, 2013 DOI URL

Nadeem M, Roche EF ("Senior"), Are Girls with Turner syndrome obese?, Irish Medical Journal, 106, (6), 2013, p188 Journal Article, 2013 URL

Cameron, F.J., de Beaufort, C., Aanstoot, H.-J., Hoey, H., Lange, K., Castano, L., Mortensen, H.B., Aman, J., Atchison, J.A., Barret, T., Bjoernedalen, H., Castro-Correia, C., Chiarelli, F., Chiari, G., Dahl-Jørgensen, K., Daneman, D., Danne, T., Dorchy, H., Fisher, L., Kaufman, F., Garandeau, P., Greene, S., Holl, R., Hougaard, P., Jarosz-Chobot, P., Kaprio, E., Kitasato, N.M., Kocova, M., Lebenthal, Y., Martul, P., Meier, L.K., Neu, A., Njolstad, P., Palmert, M., Phillips, M., Pociot, F., Robert, J.J., Robertson, K.J., Roche, E., Schoenle, E., Shalitin, S., Skinner, T.C., Skovlund, S., Sovik, O., Swift, P., Tsou, R., Urakami, T., Vanelli, M., Lessons from the Hvidoere International Study Group on childhood diabetes: Be dogmatic about outcome and flexible in approach, Pediatric Diabetes, 14, (7), 2013, p473-480 Journal Article, 2013

Montasser Nadeem, Edna F Roche ("Senior"), Bone Health in Children andAdolescents with Turner Syndrome, Journal of Pediatric Endocrinology and Metabolisim, 25, (9-10), 2012 Journal Article, 2012 URL DOI

C Machold, G Judge, A Mavrinac, J Elliott, AM Murphy, Edna F Roche ("Senior"), Social Netowrking Patterns/Hazards Among Teenagers, Irish Medical Journal , 105, (5), 2012, p151 - 152 Journal Article, 2012

G O'Malley, J Hussey, Edna F Roche ("Senior"), A Poilot Study to Profile the Lower Limb Musculoskeletal Health in Children with Obesity, Paediatric Physical Therapy, 24, (3), 2012, p292 - 298 Journal Article, 2012

Ressell M Viner, B While, T Barrett, D Candy, P Gibson, Edna F Roche et al, Assessment of childhood obesity in secondary care: OSCA consensus statement, Arch Dis Child Edu Pract Ed, 97, (3), 2012, p98 - 105 Journal Article, 2012

O'Malley G, Hussey J, Roche E.("Senior"), A pilot study to profile the lower limb musculoskeletal health in children with obesity., Pediatr Phys Ther. , 24, 2012, p292 - 298 Journal Article, 2012

Edna F Roche ("Senior"), Irish Childhood Natinal Diabetes Register, Irish Medical Journal, 104, (9), 2011, p2011- Journal Article, 2011

Viner, R.M., Roche, E., Maguire, S.A., Nicholls, D.E., When does childhood obesity become a child protection issue?, BMJ (Online), 341, (7769), 2010, p375-377 Journal Article, 2010

Viner RM, Roche E, Maguire SA, Nicholls DE., Childhood protection and obesity: a framework for practice. , British Medical journal, 341, 2010, p307 - 310 Journal Article, 2010

Roche, E. ("Senior"), Hospital based management - An irish perspective, International Journal of Pediatric Obesity, 5, (SUPPL. 1), 2010 Journal Article, 2010

O'Riordan SM, Hindmarsh P, Hill NR, Matthews DR, George S, Greally P, Canny G, Slattery D, Murphy N, Roche E, Costigan C, Hoey H., Validation of Continuous Glucose Monitoring in children and adolescents with cystic fibrosis - a prospective cohort study, Diabetes Care, 2009 Journal Article, 2009 DOI

Aisling Myers, Ieuan hughes, John Achermann, Sally Anne Lynch, Edna F Roche, Hilary Hoey, 46 XY DSD: A case of clinical and biochemical conflict, Endocrine Abstracts, British Society for Paediatric Endocrinology and Diabetes, Reading, UK, 10th - 12th November, 23, 2009, pp29- Meeting Abstract, 2009

McKenna A, Hoey H, Roche EF ("Senior"), Rising Incidence of Type 1 Diabetes Mellitus in children and adolescents under 15 years in teh Republic of Ireland 2008 (Preliminary Figures), Endroceine Abstracts (2009) 23 OC 6.1, 37th Annual meeting of the British Society for Paediatric Endocrinology and Diabetes (BESPED), Reading, UK, November 10 - 12, 2009 Meeting Abstract, 2009

S O'Connell, E O;'Mullane, J Murphy, E Roche, M Sheridan, H Hoey, Maternal smoking in pregnancy as a risk factor for Small for Gestation Age (SGA) births., British Medical Journal, 338, (2), 2009, pb481 - e 1-7 Journal Article, 2009

A Myers, J McHugh, A McCrann, N Crossadell, E Roche, H Hoey, Turner Syndrome in Young Adults: Where are They now?, Irish Paediatric Association Meeting, Mullingar, May, 2008 Poster, 2008

S O'Riordan, P Hindmarsh, C Costigan, N Murphy, E Roche, H Hoey, Insulin, C-peptide concentrations and insulin sensitivity in children with cystic fibrosis related diabetes, 47th Annual Meeting of the European Society for Paediatric Endocrinology, Istanbul, Turkey, 20 - 23 September, 2008, ESPE, 27 - 27pp Invited Talk, 2008

J Murphy, M Philip, S Macken, J Meehan, E Roche, P Mayne, M O'Regan, H Hoey, Thyroid Dysfunction in Down's Syndrome and Screening for Hypothyroidism in Children and Adolescents using Capillary TSH Measurement, Journal of Pediatric Endocrinology & Metabolism, 21, (2), 2008, p155 - 163 Journal Article, 2008

S O'Connell, E O'Mullane, A Juul, DB Dunger, EF Roche, H Hoey, Auxological characteristics of children born Small for Gestation Age without catch up growth and response to Growth Hormone Treatment, British Society for Paediatric Endocrinology and Diabetes (ESPED), Cambridge, England, September, 2007, BESPED, 29 - 29pp Invited Talk, 2007

S O'Riordan, E Roche, S George, H Hoey, B Elnazir, P Greally, G Canny, C Costigan, D Slattery, N Murphy, Continuous Glucose monitoring Enhances the Detection of Cystic Fibrosis Related Diabetes in Children with Cystic Fibrosis, The Joint Faculty of Paediatrics and Irish Paediatric Association Meeting, Limerick, May, 2007 Invited Talk, 2007

S O'Riordan, S Ennis, A Green, S George, E Hand, C Costigan, E Roche, H Hoey, Genetic Aspects of Cystic fibrosis Related Diabetes, The Joint Faculty of Paediatrics and Irish Paediatric Association Meeting, Limerick, May, 2007 Invited Talk, 2007

S O'Riordan, S George, H Hoey, E Roche, C Hilary, C Costigan J Caffery, C Corridon, E Hand, N Murphy, Dietary assessment of children and adolescents with cystic fibrosis with and without diabetes, Hormone Research, 68, 2007, p111- Journal Article, 2007

S O'Diordan, E Roche, S George, H Hoey, B Elnazir, P Greally, G Canny, C Costigan, D Slatter, N Murphy, Conitinuous Glucose Monitoring Enhances the Detection of Cystic Fibrosis Related Diabetes in Children with Cystic Fibrosis, Diabetologic, 50, (Supp 1), 2007, p190- Journal Article, 2007

S O'Riordan, H Colgan, S George, C Costigan, C Corridon, J Caffrey, E Roche, H Hoey, Diet in children with Cystic Fibrosis Related Diabetes, The Joint Faculty of Paediatrics and Irish Paediatric Assocation Meeting, Limerick, May, 2007 Invited Talk, 2007

S O'Connell, E O'Mullane, M Sheridan-Pereira, E Roche and H Hoey., Long-term growth and clinical assessment of children born small for gestational age. , Hormone Research, 68, (1), 2007, p1-67 Journal Article, 2007

S O'Connell, E O'Mullane, M Sheridan-Sheridan-Pereira, E Roche, H Hoey, Long-term growth and clinical asssessment of children born small for gestation age., Hormone Research, 68, (Supplemental 1), 2007, ppo1 - 67 Journal Article, 2007

S George, S O'Riordan, H Hoey, E Roche, C Costigan, N Murphy, quality of life and family burden in children with cystic fibrosis related diabetes., Hormone Research, 68, 2007, p89 - 90 Journal Article, 2007

S O'Connell, E O'Mullane, E Roche, M Sheridan-Pereira, H Hoey, Follow-up Assessment of Children Born Small for Gestational Age at the Coombe Women's Hospital (1999-2001), Irish Perinaltal Society, Belfast, N Ireland, March , 2007 Invited Talk, 2007

Hussey, J., Gormley, J., Bell, C., Roche, E.F., Hoey, H., Exercise tolerance and physical activity levels in children referred to a weight reduction clinic. , Irish Medical Journal, 99, (2), 2006, p46-47 Journal Article, 2006

F Healy, A Brennan, H Fitzgerald, F Cleary, E Roche, H Hoey, Insulin Pump Therapy in Children and Adolescents with Type 1 Diabetes Attending a Tertiary Referral Centre, The Irish and American Paediatric Society, Kilkenny, Ireland, September 2006, 2006 Meeting Abstract, 2006

S O'Connell, L Doyle, E O'Mullane, E Roche H Hoey, Silver Russell Syndrome (SRS): No distinction between IUGR and SGA when considering Growht Hormone Treatment?, British Society of Paeditarc Endocrinology & Diabetes, Cork, September, 2006 Invited Talk, 2006

S O'Riordan, S George, C Costigan, E Roche, H Hoey, The Prevelence of CFRD in 167 Children, American Diabetes Association, Washington DC, June , 2006 Invited Talk, 2006

S O'Rioran, S George, C Costigan, E Roche, H Hoey, Can CGMS enhance diagnosis of CFRD in 167 CF Children., American Diabetes Association, Washington DC, June , 2006 Invited Talk, 2006

S O'Riordan, S George, C Costigan, E Roche, H Hoey, CGMS in Cystic Fibrosis children, ts this the screening tool we should be using for early detection of CF related Diabestes., ISPAD, 2006 Invited Talk, 2006

S O'Riordan, S George, C Costigan, E Roche, H Hoey, Homeostasis and Continuous Glucose Monitoring in CF Childrne, Diabetes UK, March, 2006 Poster, 2006

S O'Riordan, S George, C Costigan, E Roche, H Hoey, The prevalence of IGT and CFRD by continuous glucose monitoring in children with Cystic Fibrosis, Royal College of Paediatrics and Child Health, York, England, April, 2006 Invited Talk, 2006

S O'Riordan, S George, C Costigan, E Roche, H Hoey, The prevalence of glucose intolerance and diabetes assessed by continuous glucose monitoring sensors in cystic fibrosis children., Royal College of Paediatrics And Child Helath, University of York, April, 2006, British Society for Paediatric Endocrinology and Diabetes Invited Talk, 2006

F Healy, A Brennan, H Fitzgerald, F Cleary, E Roche, H Hoey, Insulin Pump Therapy in Children and Adolescents with Type 1 Diabetes Attending a Tertiary Referral Centre, Proceedings of The Irish and American Paediatric Society 38th Annual Meeting, 2006, pp33 - 33 Conference Paper, 2006

J Hussey, J Gormley, C Bell, EF Roche, H Hoey, Exercise Tolerance and Physical Activity Levels in Children Referred to a Weight Reduction Clinic, Irish Medical Journal, 99, (2), 2006, p46 - 47 Journal Article, 2006

O'Riordan S, Hoey H, Roche EF, Costigan C, Murphy N, Screening for Diabetes in Children with Cystic Fibrosis. A new approach to CGMS analysis., 32nd Annual meeting of the International Society for Paediatric and Adolescent Diabetes (ISPAD), Cambridge, UK, September 6 - 9, 2006 Meeting Abstract, 2006

S O'Connell, H Hoey, M Sheriden-Pereirs, E Roche, E Quinn, E O'Mullane, The case for individualising treatment with growth hormone therapy in children born small for gestation age (SGA) who fail to catch up., British Society of Paediatric Endocrinology & Diabetes, Bristol, England, November, 2005 Invited Talk, 2005

J Meehan, E Roche, P Greally H Hoey., Sleep abnormalities in children with Prader Willi Syndrome., Hormone Research, 64, (Suppl 1), 2005, p291 - 291 Journal Article, 2005

Meehan J, Roche EF, Quinn E, Croasdell N, Hoey HMCV, The effects of growth hormone treatment on growth and body composition in children and adolescents with Prader Willi Syndrome, ESPE/LWPES 7th Joint Meetin Paediatric Endocrinology, Lyon, France, September 21 - 24, 2005 Meeting Abstract, 2005

S O'Connell, H Hoey, M Sheridan-Pereiar, E Roche, E Quinn, N Croasdell, Small for gestational age children who fail to catch up - are the criteria for growth hormone therapy to stringent?, Hormone Research, 64, (Supplemental 1), 2005 Journal Article, 2005

S O'Riordan, S George, C Costigan, E Roche, H Hoey, Cystic Fibrosis Diabestes and non-diabetes, North American CF Meeting, Baltimore, USA, October , 2005 Poster, 2005

S O'Connell, E O'Mullane, JP Murphy, EF Roche, M Sheridan-Pereira, H Hoey, Follow of assessment of children born small for gestation age at the Coombe Women's Hospital (1999 - 2001), Irish Journal of Medical Science, 174, (4), 2005, p1 - 71 Journal Article, 2005

Meehan J, Roche EF, Quinn E, Crosadell N, Hoey HMCV, The effects of growth hormone treatment on growth and body composition in children and adolescents with Prader Willi Syndrome, Hormone Research, 64, (S 1), 2005, p297- Journal Article, 2005

L Doyle, S O'Connell, EF Roche, H Hoey, Silver Russell Syndrome - The spectrum of Clinical features, growth outcome and moleculare genetics in a study of 9 patients attending a paediatric Endocrinology clinic., Irish Journal of Medical Sciences , 174, (4), 2005, p1 - 71 Journal Article, 2005

Hoey, H., Roche, E.F., Meehan, J., Auxology and growth assessment, Irish Medical Journal, 98, (6), 2005 Journal Article, 2005

Roche EF ("Senior author"), Menon A, GillD , Hoey HMCV , Clinical Presentation of Type 1 Diabetes, Paediatric Diabetes , 6, (2), 2005, p75 - 8 Journal Article, 2005

J Meehan, E Roche, P Greally, H Hoey, Sleep abnormalities in children with Prader Willi Syndrome, European Society for Paediatric Endocrinology Scientfiic Meeting, 2005, 2005 Invited Talk, 2005

S O'Connell, M Sheridan-Pereira, H Hoey, E Roche, Small for gestation age (SGA) children - Childhood growth outcomes and final adult height., Journal of Maternal-Fetal & Neonatal Medicine, 18, (3), 2005, p203- Journal Article, 2005

S O'Riordan, S George, C Costigan, E Roche, H Hoey, Cystic Fibrosis Diabetes - The Dublin Experience, International Society of Paediatric Adolescence Diabetes (ISPAD), Krakow, 2005, 2005 Poster, 2005

J Murphy, HMCV Hoey, M Philip, EF Roche, S Macken, P Mayne, D Duff, M O'Keefe, D McShane, E Fogarty, M O'Regan, Guideline for the Medical Management fo Irish Children and Adolescents with Down Syndrome, Irish Medical Journal, 98, (2), 2005, p48 - 52 Journal Article, 2005

M Parvin, H Hoey, E Roche, C Costigan, Treatment Outcome in Turner Syndrome, Irish Medical Journal, 97, (1), 2004, p12 - 15 Journal Article, 2004

H Hoey, E Roche, J Meehan, Effect of discontinuation of growth hormone treatment on risk factors for cardiovascular disease in abdolescents born small for gestation age, Hospital Doctor of Ireland, 9, (3), 2004 Journal Article, 2004

Hussey J, Dowling C, Al Basairi I, Roche EF, O'Riordan S, Croasdell N, Spelman M, Hoey HMCV, Physical Activity levels, Exercise Tolerance and Psychological Profile in children referred to an Obesity Clinic, Irish Journal of Medical Science, 2003 Journal Article, 2003

O'Riordan S, Delanghe K, Brennan A, Leen G, Roche EF, Greally P, Hoey HMCV, Cystic Fibrosis related diabetes (CFRD) and impaired glcose tolerance in the National Chilren's Hospital, Tallaght., Irish Paediatric Association Meeting, Atlone, Ireland, May 9 - 10, 2003 Meeting Abstract, 2003

Delangeh K, O'Riordan S, Brennan A, Roche EF, Hoey HMCV, Diabetes Type 1 and Associated Coeliac Disease, Irish Journal of Medical Science, 2003 Journal Article, 2003

Hussey J, Dowling C, Al Basairi I, Roche EF, O'Riordan S, Croasdell N, Spelman M, Hoey HMCV, Physical Activity Levels, Exercise Tolerance and Psychologiacl Profile in Children referred to an Obesity Clinic, Irish Paediatric Association Meeting, Atlone, Ireland, May 9 - 10, 2003 Meeting Abstract, 2003

Roche EF, Hoey HMCV, Warnign of the type 2 epidemic? Not so simple obesity, Irish Jorunal of Medical Science, 2003 Journal Article, 2003

E Roche, H Lewy, H Hoey, Z Laron, Differences between males and females in the seasonality of birth and month of clinical onset of disease in children with type 1 diabetes mellitus in Ireland, Journal of Pediatric Endocrinology & Metabolism, 16, (5), 2003, p779 - 782 Journal Article, 2003

Mohamed S, Roche EF, Quinn E, Eltahir M, Hoey HMCV, Meddle ear disease, hearing loss and learning difficulty in Irish girls with Turner syndrome, Irish Journal of Medical Science, 2003 Journal Article, 2003

H Hoey, E Roche, J Meehan, Paediatric Endocrinology, Hospital Doctor of Ireland, 9, (3), 2003 Journal Article, 2003

Roche EF., Charmandari E., Dattani M, Hindmarsh PC , Blood Pressure in children and adolescents with Congenital Adrenal Hyperplasia, (21-Hydroxylase Deficiency): a preliminary report., Clinical Endocrinology , 58, 2003, p589 - 596 Journal Article, 2003

Delanghe K, O'Riordan S, Brennan A, Roche EF, Hoey HMCV, Diabetes Type 1 and Associated Coeliac Disease, Irish Paediatric Assocation Meeting, Athlone, Ireland, May 9 - 10, 2003 Meeting Abstract, 2003

O'Riordan S, Delangeh K, Brennan A, Leen G, Roche EF, Greally P, Hoey HMCV, Cystic Fibrosis related diabetes (CFRD) and impaired glucose tolerance in the National Chilren's Hosptial, Tallaght., Irish Journal of Medical Science, 2003 Journal Article, 2003

Roche EF ("Senior"), Childhood Obesity - why should we be worried? Editorial. , Irish Medical Journal , 96, (4), 2003, p100 - 102 Journal Article, 2003

Roche EF, Samaan C, Brennan Aa, Fitzgerald H, Hoey HMCV, The role of continuous glucose monitoring in the management of type 1 diabetes, Irish Journal of Medical Science, 2003 Journal Article, 2003

Roche EF, Hoey HMCV, Warning of the type 2 epidemic? Not so simple obesity, Joint Irish Paediatric Association/Ulster Paediatric Society Meeting, Northern Ireland, May 10 - 11, 2002 Meeting Abstract, 2002

Roche EF, Charmandari E, Dattani M, Hindermarsh PC, Blood Pressure in patients with Congenital Adrenal Hyperplasia, 21 - Hbdroxylase Deficiency, 41st Annual Meetin of the european Society for Paediatic Endocrinology (ESPE), Madrid, Spain, September 25 - 28, 2002 Meeting Abstract, 2002

Roche EF ("Senior"), Strategic Management, MA Healthcare Management, Distance Learning Study Text Book, 2nd Edition, Institute of Public Administratin Publicastions, Dublin, 2002 Book, 2002

E Roche, A Menon, D Gill, H Hoey, Incidence of Type 1 Diabetes Mellitus in Childrne Ages Under 15 years in the Republic of Ireland, Journal of Paediatric Endocrinology & Methabolism, 15, 2002, p1191 - 1194 Journal Article, 2002

E Roche, A Menon, D Gill, H Hoey, National Incidence of Type 1 Diabetes in Childhood and Adolescence, Irish Medical Journal, 95, (4), 2002, p115 - 118 Journal Article, 2002

Roche EF ("Senior"), Obesity - The Clinician's View, XXIV Congress of the European Society of Cardiology, Berlin, Germany, Aug 31 - Sept 4, 2002 Invited Talk, 2002

Roche EF, Samaan C, Brennan A, Fitgerald H, Hoey HMCV, The role of continuous glocose monitoring in the management of type 1 diabetis, Irish Paediatric Association meeting, Dublin, Ireland, November 28, 2002 Meeting Abstract, 2002

Roche EF, Hoey HMCV, Clincial Features of Type 1 Diabetes, 28th Annual meeting of the International Society for Paediatric and Adolescent Diabetes (ISPAD), Graz, Austria, September 18 - 21, 2002 Meeting Abstract, 2002

Roche EF, Charmandari E, Dattani M, Hindmarsh PC, Blood Pressure in patiens with Congenital Adrenal Hyperplasia, 21 - Hydroxylase Deficiency, Hormone Research, 58, (Sup 2), 2002, p45- Journal Article, 2002

Roche EF, Menon A, Gill D, Hoey HMCV, The Incidence of Type 1 Diabetes in children aged under 15 years in the Republic of Ireland, Journal of Paediatic Endocrinology and Metabolism, 15, (8), 2002, p1191 - 1194 Journal Article, 2002

Roche EF, Hoey HMCV, Clinical Features of Type 1 Diabetes, Journal of Paediatic Endocrinology and Metabolism, 15, 2002, p1087 - 1087 Journal Article, 2002

Roche EF ("Senior"), the Management of Intersex Conditions, Annual Paediatric Endocrinology Meeting, Bromsgrove, Birmingham, UK, November , 2002 Invited Talk, 2002

Roche EF, Menon A, Gill D, Hoey HMCV, The Incidence fo Insulin Dependent Diabetes Mellitus in the Irish Republic, Paediatric Research , 49, (6), 2001, p93 - 93 Journal Article, 2001

Roche EF, Hindmarsh PC, A clinical delemma. Sex of Rearing? A case report of 11-B hydroxylase deficiency, Paediatric Research, 49, (6), 2001, p120 - 120 Journal Article, 2001

Roche EF, Menon A, Gill D, Hoey HMCV, The Incidence of Insulin Dependent Diabetes Mellitus in the Irish Republic, Joint meeting of the European Society of Paediatric endocrinology (ESPE) and the Lawson Wilkins Society (North American Society of Paedaitric Endocrinology), Montreal, Canada, 2001 Meeting Abstract, 2001

Roche EF, Hindmarsh PC, A clincal delemma. SEx of rearing? A case report of 11-B Hydroxylase deficiency, Joint meeting of the European Society of paediatic Endocrinology (ESPE) and the Lawson Wilkins Society (North American Society of Paediatric Endocrinology), Montreal, Canada, 2001 Meeting Abstract, 2001

Roche EF ("Senior"), Strategic Management, MA Healthcare Management, 1st Edition, Dublin, Institute of Public Administratino Publication, 1996 Book, 1996

Fearon, U., Clarke, D., McKenna, T.J., Cunningham, S.K., Morrison, P.J., Hughes, A.E., Nevin, N.C., Russell, C.F.J., Powell, D., Hadden, D.R., Bonar, B.D., Smith, D.F., Darke, C., Hetherton, A.M., Smyth, P.P.A., Hunter, S.J., Harper, R., Ennis, C.N., Crothers, E., Sheridan, B., Atkinson, A.B., Bell, P.M., Hayes, F., McKenna, T.J., Sheahan, K., McCabe, M., Conway, D.J., O'Higgins, N.J., Smyth, P.P.A., Garry, P., Laski, J., Brosnan, L., Collins, P., Devlin, J.G., Heaney, A.P., Atkinson, A.B., Curry, W.J., Johnston, C.F., Buchanan, K.D., Sheridan, B., Mirakhur, M., Fiad, T.M., Culliton, M., Cunningham, S.K., McKenna, T.J., Lynn, J.A., O'Shea, D.B., Meeran, M.K., Jackson, J.A., Bloom, S.R., Hunter, S.J., Ennis, C.N., Sheridan, B., Atkinson, A.B., Bell, P.M., Hayes, F., McKenna, T.J., Sheehan, K., Hayes, F., Heffernan, A., McKenna, T.J., Nugent, A.G., McGurk, C., Rutherford, R., Hayes, J.R., Johnson, G.D., Cusack, Y.A., O'Riordan, D., McDermott, E.W.M., O'Higgins, N.J., Smyth, P.P.A., Roche, E.F., McCormack, I., Tempany, E.T., Smyth, P.P.A., Smith, D.S., Deegan, P., Owens, D., Gilligan, S., Collins, P., Johnson, A., Tomkin, G.H., Heaney, A., Harper, R., Ennis, C., Sheridan, B., Atkinson, A.B., Bell, P.M., Wiggam, M.I., O'Kane, M.J., Harper, R., Atkinson, A.B., Hadden, D.R., Trimble, E.R., Bell, P.M., Dunne, F.P., Heath, D.A., Rollason, T., Ratcliffe, W.A., Marshall, T., Cronin, C.C., Barry, D.G., Crowley, B., Ferriss, J.B., Kinsley, B.T., Simonson, D.C., Jones, R., Owens, D., Collins, P., Johnson, A., Tomkin, G.H., Fiad, T.M., Culliton, M., Cunningham, S.K., McKenna, T.J., O'Shea, D.B., Lambert, P.D., Bloom, S.R., Herbert, J., O'Hare, J.A., Abuaisha, F., Razza, Q., Geoghegan, M., Barrett, E., Clarke, D., Fearon, U., Cunningham, S.K., McKenna, T.J., Irish endocrine society - Proceedings of the 19th annual meeting of the Irish endocrine society held at University College Hospital, Galway in October 1994, Irish Journal of Medical Science, 164, (4), 1995, p320-328 Journal Article, 1995

Non-Peer-Reviewed Publications

Edna F Roche ("Senior"), "Optimising Care in Down Syndrome", Royal College of Physicians (RCPI) Masterclass Broadening Horizons in Down Syndrome, Royal College of Physicians Of Ireland (RCPI), Kildare St, 1st February , 2017, Royal College of Physicians (RCPI) Invited Talk, 2017

Edna F Roche ("Senior"), "Medical Management of Down Syndrome Health Surveillance Guidelines" , Annual Meeting of the Faculty of Paediatrics, Royal College of Physicians of Ireland, , Royal College of Physicians of Ireland, Kildare Street, May 12th 2017, 2017, Faculty of Paediatrics, Royal College of Physicians of Ireland, Invited Talk, 2017

Edna Roche, Symposium on Adolescent Health, 29th Novrember 2017, In:Lost in Transition, 2017, Trinity Centre for Health Sciences, Tallaght Hospital Meetings /Conferences Organised, 2017

Edna F Roche ("Senior"), "Who's Feeding the Kids Online? Digital Food Marketing and Children in Ireland - the Doctor's Perspective" , "Who's Feeding the Kids Online? Digital Food Marketing and Children in Ireland - Irish Heart Foundation Seminar, he Lighthouse Cinema, Dublin, 15th June, 2016, Irish Heart Foundation Invited Talk, 2016

Edna F Roche ("Senior"), "The Irish Childhood Diabetes National Register (ICDNR) -the Current Picture of Type 1 Diabetes in children and Adolescents in Ireland" , Inaugural Meeting of the Irish Paediatric Endocrinology and Diabetes Group, Athlone, 27th-28th May , 2016 Invited Talk, 2016

Edna Roche, "PROMISE -Implications for clinical pathways in primary and secondary care" Respondant, Findings from the PROMISE programme and next steps for treatments of obesity in children and young peoplePaediatric Research in Obesity Multi-modal Intervention and Service Evaluation Programme (PROMISE) , University College London, Institute of Child Health London, 10th June, 2015 Invited Talk, 2015

Roche, Meet the Expert- Challenges in the Management of Extreme Obesity (2), ESPE 53rd Annual Meeting , Convention Centre Dublin, 20 September 2014, 2014, European society for Paediatric Endocrinology Invited Talk, 2014

Edna Roche, Russell Viner and OSCA, Progressing Paediatrics Workshop " Managing Childhood Obesity", 24th October 2014, In: Progressing Paediatrics Workshop " Managing Childhood Obesity", 2014, Royal College Of Paediatrics and Child Health, London Meetings /Conferences Organised, 2014

Edna Roche , 28th ESPE Summer School, 15-17 September 2014, In:28th ESPE Summer School, 2014, Barretstown Castle, Co Kildare Meetings /Conferences Organised, 2014

Edna Roche ("Senior"), Meet the Expert- Challenges in the Management of Extreme Obesity, ESPE 53rd Annual Meeting , Convention Centre Dublin, 18 September 2014, 2014, European society for Paediatric Endocrinology Invited Talk, 2014

Edna F Roche , "Assessment of Obese children and obesity co-morbidities using the OSCA guidelines", Progressing Obesity Management: Training Course in Management of Obesity , Royal College of Paediatrics and Child Health (RCPCH), London, 24th October, 2014, Edna Roche and Russell Viner Invited Talk, 2014

Edna F Roche (, "Extreme obesity in childhood" , Faculty of Paediatrics Autumn Conference, Royal College of Physicians Of Ireland (RCPI), Kildare St, Friday October 10th , 2014 Invited Talk, 2014

Edna Roche and Hilary Hoey, ESPE 53rd Annual Meeting , 18-20 September 2014, In: 53rd Annual Meeting of the European Society of Paediatric Endocrinology (ESPE), 2014, Convention Centre Dublin Meetings /Conferences Organised, 2014

Edna Roche, Festschrift Clinical Challenges in Paediatrics and Child Health and Opportunities for the Future , 17th September 2010, In:Clinical Challenges in Paediatrics and Child Health and Opportunities for the Future , 2010, Tallaght Hospital Dublin Meetings /Conferences Organised, 2010

Murphy JP, Philip M, Roche EF, Hoey HMCV, comprehensive Surveillance study of children and adolescents with down Syndrome, Birth to 16 years in the Eastern Regional Health Authority, 2003 Report, 2003

Roche EF ("Senior"), changing structures and practices in the Irish health service, Department of Health and Chidlren, Dublin, Forum on Medical manpower, 1999 Report, 1999

Research Expertise

Projects

  • Title
    • Irish Childhood Diabetes National Register
  • Summary
    • Diabetes Epidemiology: Childhood Type 1 diabetes (T1D), fatal if untreated is associated with major life limiting complications if poorly controlled. Good diabetes management requires accurate disease data. No such data were available in Ireland. Following a baseline study of national T1D epidemiology, the Irish Childhood National Diabetes Register (ICDNR), a core infrastructure in childhood diabetes, was established to provide accurate data regarding T1D in children and young people in Ireland. The ICDNR now in its 12th year, is governed by a highly skilled Steering Group, with a broad range of expertise (Medical, Nursing, IT, Statistics, Health Informatics). It has extensive collaborations: International (Eurodiab, NI Register, Hvidore, ISPAD) and National (Paediatricians, Diabetologists, RCPI, PCRS, HSE, Diabetes Ireland, TUD (formerly IT Tallaght). As a result of our work accurate national data are available for the first time to inform health planning, resource allocation, enable audit, research and optimise clinical care. Targeted interventions are now possible as patient subgroups are identifiable. Robust data and forecasts are provided to the HSE (by ICDNR). Reliable incidence data are available ( considered "a Basic Health Indicator" by WHO), of national and international importance and Irish T1D epidemiology monitored. Prevalence Modelling: Current research includes prevalence modelling and forecasting in T1D in association with Professor Myra O'Regan, Department of Statistics and Computer Science. Diabetic Ketoacidosis Prevention: Some children develop severe metabolic decompensation (Diabetic Ketoacidosis, DKA) at diabetes diagnosis which can be fatal or result in a trajectory of poor metabolic control with increased diabetes related complications in adult life. This is of major international concern. The Irish Childhood Diabetes National Register (ICDNR) is monitoring national DKA rates before and after a 2 year collaborative national DKA prevention campaign to gain insight into factors associated with the development of DKA and its prevention. Analysis of the baseline data demonstrates a very high rate of DKA at diagnosis in those with T1D. The intervention phase is in progress with print and radio campaigns and targeted campaigns directed at healthcare professionals. A digital campaign has been developed for phase two. This study is a collaboration involving Diabetes Ireland, TUD (formerly IT Tallaght) and the ICDNR.
  • Funding Agency
    • National Children's Hospital Foundation
  • Date From
    • 1/1/2008
  • Date To
    • ongoing
  • Title
    • International Monitoring of Diabetes Epidemiology
  • Summary
    • Eurodiab is an international collaboration of 26 European Childhood Diabetes Registers representing 22 countries. Following assessment and site visit the ICDNR has been a participant since 2011. Eurodiab monitors the epidemiology of T1D across Europe exploring trends in incidence which may ultimately provide clues to the underlying aeitology.
  • Date From
    • 2011
  • Title
    • Down Syndrome National Register
  • Summary
    • Down Syndrome (DS) or trisomy 21 is one of the most common congenital genetic conditions. Ireland is thought to have the highest incidence of DS in the world. While much is known about Down Syndrome there is much that we need to learn. The National Register for Children with Down Syndrome was established in 2015 to increase our knowledge about Down Syndrome in Irish children with the ultimate aim of improving the quality of care and quality of life for children with DS and their families. The unique prospective National Register for DS was developed in 2015, with extensive collaborations. The DS register is a key infrastructure to provide reliable data to inform clinical care, support audit, research and enhance the quality of life for children with DS and their families. This prospective national Register will define the epidemiology of Down Syndrome in Ireland and provide data to inform appropriate healthcare planning, clinical audit, and enable monitoring of the implementation of the medical management guidelines for those with DS (MMG) developed by our group. These data, including the number of children born with Down syndrome in Ireland each year, the area in which they live etc ,will enable more informed decision making and optimise resource allocation leading to better clinical outcomes. The Register will also expand our knowledge of DS. It will help ascertain if certain problems and illnesses are more prevalent or more severe in children with Down syndrome. It will provide more accurate evidence based information for counselling families and may enable screening programmes or early intervention to prevent avoidable secondary disability which has been so successful for those with DS who develop thyroid disease for example. The immediate research plan is to define incidence, demographics and co-morbidities in newborns with DS. The longitudinal arm will explore the natural history of co-morbidities, complications, access to and health care utilisation etc. In addition Down Syndrome provides an important model to evaluate immune function. Through defining the epidemiology and systematically studying the issues faced by children with DS and their families the DS Register will enhance the health and well being of Children with Down syndrome in Ireland. The DS Register is governed by a Steering Group with a broad expertise and includes parent representation. The Register is hosted by Tallaght University Hospital and funded by the NCHF.
  • Funding Agency
    • National Childrens' Hospital Foundation (NCHF)
  • Date From
    • 2015
  • Title
    • PACE Study
  • Summary
    • Intervention to improve youth question-asking and provider education during paediatric diabetes visits.
  • Funding Agency
    • National Childrens' Research Centre NCRC
  • Date From
    • 2018

Recognition

Awards and Honours

The John Good Prize, The University of Dublin, Trinity College Dublin 1990

The Sir Charles Harvey Award for outstanding performance in postgraduate management education, the Irish Management Institute 1990

The Provost's Award for Teaching Excellence, The University of Dublin, Trinity College Dublin 2003

Healthcare Team of the Year Award 2016 (Large Hospital category) awarded to the Paediatric and Adolescent Diabetes Service, NCH Tallaght, Irish Healthcare Awards 2017

Best Poster Prize at the 45th Annual Meeting of the British Society for Paediatric Endocrinology and Diabetes, Newcastle, UK. November 22nd-24th 2017. 2017

The Inaugural Jennings Medal awarded by the Irish Endocrine Society Awarded for the Best Paediatric Paper submitted to the Irish Endocrine Society National Meeting, October 11th 2019, Galway. 2019