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David Mc Connell
Fellow Emeritus, Genetics

Publications and Further Research Outputs

Peer-Reviewed Publications

Freeman AR, MacHugh DE, McKeown S, Walzer C, McConnell DJ, Bradley DG, Sequence variation in the mitochondrial DNA control region of wild African cheetahs (Acinonyx jubatus)., Heredity, 86, (Pt 3), 2001, p355-62 Journal Article, 2001

Hobson AH, Buckley CM, Jørgensen ST, Diderichsen B, McConnell DJ, Interaction of the Pseudomonas cepacia DSM3959 lipase with its chaperone, LimA., Journal of biochemistry, 118, (3), 1995, p575-81 Journal Article, 1995

Gallagher PM, Ward P, Tan S, Naughten E, Kraus JP, Sellar GC, McConnell DJ, Graham I, Whitehead AS, High frequency (71%) of cystathionine beta-synthase mutation G307S in Irish homocystinuria patients., Human mutation, 6, (2), 1995, p177-80 Journal Article, 1995

Kelly AP, Diderichsen B, Jorgensen S, McConnell DJ, Molecular genetic analysis of the pullulanase B gene of Bacillus acidopullulyticus., FEMS microbiology letters, 115, (1), 1994, p97-105 Journal Article, 1994

Aamand JL, Hobson AH, Buckley CM, Jørgensen ST, Diderichsen B, McConnell DJ, Chaperone-mediated activation in vivo of a Pseudomonas cepacia lipase., Molecular & general genetics : MGG, 245, (5), 1994, p556-64 Journal Article, 1994

McDonnell GE, McConnell DJ, Overproduction, isolation, and DNA-binding characteristics of Xre, the repressor protein from the Bacillus subtilis defective prophage PBSX., Journal of bacteriology, 176, (18), 1994, p5831-4 Journal Article, 1994

McDonnell GE, Wood H, Devine KM, McConnell DJ, Genetic control of bacterial suicide: regulation of the induction of PBSX in Bacillus subtilis., Journal of bacteriology, 176, (18), 1994, p5820-30 Journal Article, 1994 TARA - Full Text

Wang H, O'Mahony DJ, McConnell DJ, Qi SZ, Optimization of the synthesis of porcine somatotropin in Escherichia coli., Applied microbiology and biotechnology, 39, (3), 1993, p324-8 Journal Article, 1993

Hobson AH, Buckley CM, Aamand JL, Jørgensen ST, Diderichsen B, McConnell DJ, Activation of a bacterial lipase by its chaperone., Proceedings of the National Academy of Sciences of the United States of America, 90, (12), 1993, p5682-6 Journal Article, 1993

Kiang, A.-S., Connolly, V., McConnell, D.J., Kavanagh, T.A., Cytoplasmic male sterility (CMS) in Lolium perenne L.: 1. Development of a diagnostic probe for the male-sterile cytoplasm, Theoretical and Applied Genetics, 86, (6), 1993, p781-787 Journal Article, 1993 DOI

Oliver SG, van der Aart QJ, Agostoni-Carbone ML, Aigle M, Alberghina L, Alexandraki D, Antoine G, Anwar R, Ballesta JP, Benit P, The complete DNA sequence of yeast chromosome III., Nature, 357, (6373), 1992, p38-46 Journal Article, 1992

Wood HE, Devine KM, McConnell DJ, Characterisation of a repressor gene (xre) and a temperature-sensitive allele from the Bacillus subtilis prophage, PBSX., Gene, 96, (1), 1990, p83-8 Journal Article, 1990

Butler G, Dawes IW, McConnell DJ, TUF factor binds to the upstream region of the pyruvate decarboxylase structural gene (PDC1) of Saccharomyces cerevisiae., Molecular & general genetics : MGG, 223, (3), 1990, p449-56 Journal Article, 1990

Wood HE, Dawson MT, Devine KM, McConnell DJ, Characterization of PBSX, a defective prophage of Bacillus subtilis., Journal of bacteriology, 172, (5), 1990, p2667-74 Journal Article, 1990 TARA - Full Text

O'Mahony DJ, Wang HY, McConnell DJ, Jia F, Zhou SW, Yin D, Qi S, The effect of phage T7 lysozyme on the production of biologically active porcine somatotropin in Escherichia coli from a gene transcribed by T7 RNA polymerase., Gene, 91, (2), 1990, p275-9 Journal Article, 1990

Wang HY, McConnell DJ, O'Mahony DJ, An efficient temperature-inducible vector incorporating the T7 gene 10 translation initiation leader region., Nucleic acids research, 18, (4), 1990, p1070 Journal Article, 1990

O'Reilly C, Black GW, Laffey R, McConnell DJ, Molecular analysis of an IS200 insertion in the gpt gene of Salmonella typhimurium LT2., Journal of bacteriology, 172, (11), 1990, p6599-601 Journal Article, 1990

Bradley DG, Farrar GJ, Sharp EM, Kenna P, Humphries MM, McConnell DJ, Daiger SP, McWilliam P, Humphries P, Autosomal dominant retinitis pigmentosa: exclusion of the gene from the short arm of chromosome 1 including the region surrounding the rhesus locus., American journal of human genetics, 44, (4), 1989, p570-6 Journal Article, 1989

Daiger SP, Humphries MM, Giesenschlag N, Sharp E, McWilliam P, Farrer J, Bradley D, Kenna P, McConnell DJ, Sparkes RS, Linkage analysis of human chromosome 4: exclusion of autosomal dominant retinitis pigmentosa (ADRP) and detection of new linkage groups., Cytogenetics and cell genetics, 50, (4), 1989, p181-7 Journal Article, 1989

P. McWilliam, G. J. Farrar, P. Kenna, D. G. Bradley, M. M. Humphries, E. M. Sharp, D. J. McConnell, M. Lawler, D. Sheils, C. Ryan and et al., Autosomal dominant retinitis pigmentosa (ADRP): localization of an ADRP gene to the long arm of chromosome 3, Genomics, 5, (3), 1989, p619-22 Journal Article, 1989 URL

O'Mahony DJ, Wang H, McConnell DJ, Jia F, Xia L, Qi S, Polymorphism in porcine somatotropin cDNA sequences., Animal genetics, 20, (3), 1989, p313-6 Journal Article, 1989

G. J. Farrar, P. McWilliam, E. M. Sharp, P. Kenna, D. G. Bradley, M. M. Humphries, D. J. McConnell and P. Humphries, Autosomal dominant retinitis pigmentosa: exclusion of a gene from extensive regions of chromosomes 6, 13, 20, and 21, Genomics, 5, (3), 1989, p612-8 Journal Article, 1989 URL

Devine KM, Hogan ST, Higgins DG, McConnell DJ, Replication and segregational stability of Bacillus plasmid pBAA1., Journal of bacteriology, 171, (2), 1989, p1166-72 Journal Article, 1989 TARA - Full Text

Malarial proteinase? [7], Higgins, D.G., McConnell, D.J., Sharp, P.M., Nature, 340, (6235), 1989, p604 Journal Article, 1989

Laoide BM, Chambliss GH, McConnell DJ, Bacillus licheniformis alpha-amylase gene, amyL, is subject to promoter-independent catabolite repression in Bacillus subtilis., Journal of bacteriology, 171, (5), 1989, p2435-42 Journal Article, 1989

Farrar GJ, Geraghty MT, Moloney JM, McConnell DJ, Humphries P, Linkage analysis of X linked retinitis pigmentosa in the Irish population., Journal of medical genetics, 25, (4), 1988, p222-6 Journal Article, 1988

Akhtar MW, Duffy M, Dowds BC, Sheehan MC, McConnell DJ, Multigene families of Cellulomonas flavigena encoding endo-beta-1,4-glucanases (CM-cellulases)., Gene, 74, (2), 1988, p549-53 Journal Article, 1988

Croke, D.T., Blau, W., OhUigin, C., Kelly, J.M., McConnell, D.J. , Photolysis of phosphodiester bonds in plasmid DNA by high intensity UV laser irradiation. , Photochemistry and Photobiology, 47, (4), 1988, p527 - 536 Journal Article, 1988 URL DOI

Butler G, McConnell DJ, Identification of an upstream activation site in the pyruvate decarboxylase structural gene (PDC1) of Saccharomyces cerevisiae., Current genetics, 14, (5), 1988, p405-12 Journal Article, 1988

Shields, D., McConnell, D.J., Winder, F.G., Cloning of part of the gene for bovine deoxyribonuclease I, Biochemical Society Transactions, 16, (2), 1988, p195-196 Journal Article, 1988

David T. Choke, Werner Blau, Colm Ohuigin, John M. Kelly, David J. Mcconnell , Photolysis of phosphodiester bonds in plasmid DNA by high intensity UV laser irradiation., Photochemistry and Photobiology, 47, (4), 1988, p527 - 536 Journal Article, 1988 URL DOI

Kelly JM, van der Putten WJ, McConnell DJ., Laser flash spectroscopy of methylene blue with nucleic acids, Photochemistry and Photobiology, 45, (2), 1987, p167 - 175 Journal Article, 1987 URL DOI

Sharp, P.M., Devine, K.M., Codon usage and gene expression level in Dictyosteiium discoidtum: Highly expressed genes do [prefer[ optimal codons, Nucleic Acids Research, 17, (3), 1987, p5029-5040 Journal Article, 1987 DOI

John M. Kelly, David J. McConnell, Colm OhUigin, Alessandro B. Tossi, Andree Kirsch-De Mesmaeker, Axel Masschelein and Jacques Nasielski, Ruthenium polypyridyl complexes; their interaction with DNA and their role as sensitisers for its photocleavage, Chemical Communications, 1987, p1821 - 1823 Journal Article, 1987 DOI URL

C OhUigin, D J McConnell, J M Kelly, and W J van der Putten, Methylene blue photosensitised strand cleavage of DNA: effects of dye binding and oxygen., Nucleic Acids Research, 15, 1987, p7411 - 7427 Journal Article, 1987 URL URL

Magan, J.D., Blau, W., Croke, D.T., McConnell, D.J., Kelly, J.M. , One-dimensional photoconductivity in DNA, Chemical Physics Letters, 141, (6), 1987, p489 - 492 Journal Article, 1987 DOI URL

Werner Blau, David T. Croke, John M. Kelly, David J. McConnell, Colm OhUigin and Wilehlm J. M. Van der Putten, Base-specific photocleavage of DNA induced by nanosecond U.V. pulsed laser radiation or methylene blue sensitisation, Journal of the Chemical Society, Chemical Communications , 10, 1987, p751 - 752 Journal Article, 1987 DOI TARA - Full Text URL

Dowds BC, Murphy P, McConnell DJ, Devine KM, Relationship among oxidative stress, growth cycle, and sporulation in Bacillus subtilis., Journal of bacteriology, 169, (12), 1987, p5771-5 Journal Article, 1987 TARA - Full Text

Murphy NB, McConnell DJ, Schwarz TF, Expression of the gene for NAD-dependent glucose-6-phosphate dehydrogenase from Leuconostoc mesenteroides cloned in Escherichia coli K-12., Journal of bacteriology, 169, (1), 1987, p334-9 Journal Article, 1987

Kelly JM, van der Putten WJ, McConnell DJ, Laser flash spectroscopy of methylene blue with nucleic acids., Photochemistry and photobiology, 45, (2), 1987, p167-75 Journal Article, 1987

Cantwell, Barbara A., McConnell, David J. , TRANSFORMATION OF BREWING YEAST STRAINS, Biological Research on Industrial Yeasts, Symposium on the Biochemistry and Molecular Biology of Industrial Yeasts, Kalamazoo, MI, USA, 1987 Conference Paper, 1987

Murphy P, Dowds BC, McConnell DJ, Devine KM, Oxidative stress and growth temperature in Bacillus subtilis., Journal of bacteriology, 169, (12), 1987, p5766-70 Journal Article, 1987 TARA - Full Text

McConnell DJ, Cantwell BA, Devine KM, Forage AJ, Laoide BM, O'Kane C, Ollington JF, Sharp PM, Genetic engineering of extracellular enzyme systems of Bacilli., Annals of the New York Academy of Sciences, 469, 1986, p1-17 Journal Article, 1986

McConnell, D.J.., Methods and achievements of genetic engineering: Prospects in agriculture. A review, Livestock Production Science, 15, (2), 1986, p109-131 Journal Article, 1986

Cantwell1, B.A., Brazil, G., Murphy, N., McConnell, D.J., Comparison of expression of the endo-β-1,3-1,4-glucanase gene from Bacillus subtilis in Saccharomyces cerevisiae from the CYC1 and ADH1 promoters, Current Genetics, 11, (1), 1986, p65-70 Journal Article, 1986 DOI

O'Kane C, Stephens MA, McConnell D, Integrable alpha-amylase plasmid for generating random transcriptional fusions in Bacillus subtilis., Journal of bacteriology, 168, (2), 1986, p973-81 Journal Article, 1986

J M Kelly, A B Tossi, D J McConnell, and C OhUigin, A study of the interactions of some polypyridylruthenium (II) complexes with DNA using fluorescence spectroscopy, topoisomerisation and thermal denaturation., Nucleic Acids Research, 13, (17), 1985, p6017 - 6034 Journal Article, 1985 URL URL

McWilliam P, Mahon GA, McConnell DJ, Verification of a new model of the time course of RNA synthesis. Measurement of the rates of initiation and elongation., Biochimica et biophysica acta, 824, (2), 1985, p121-7 Journal Article, 1985

Sharp PM, Rogers MS, McConnell DJ, Selection pressures on codon usage in the complete genome of bacteriophage T7., Journal of molecular evolution, 21, (2), 1985, p150-60 Journal Article, 1985

O'Kane, C., Cantwell, B.A., McConnell, D.J., Mapping of the gene for endo-β-1,3-1,4-glucanase of Bacillus subtilis, FEMS Microbiology Letters, 29, (1-2), 1985, p135-139 Journal Article, 1985

Kelly JM, Murphy MJ, McConnell DJ, OhUigin C., A comparative study of the interaction of 5,10,15,20-tetrakis (N-methylpyridinium-4-yl)porphyrin and its zinc complex with DNA using fluorescence spectroscopy and topoisomerisation., Nucleic Acids Research, 13, (1), 1985, p167 - 184 Journal Article, 1985 URL URL

Stephens MA, Ortlepp SA, Ollington JF, McConnell DJ, Nucleotide sequence of the 5' region of the Bacillus licheniformis alpha-amylase gene: comparison with the B. amyloliquefaciens gene., Journal of bacteriology, 158, (1), 1984, p369-72 Journal Article, 1984

O'Reilly C, Turner PD, Smith-Keary PF, McConnell DJ, Molecular cloning of genes involved in purine biosynthetic and salvage pathways of Salmonella typhimurium., Molecular & general genetics : MGG, 196, (1), 1984, p152-7 Journal Article, 1984

Murphy, N., Mcconnell, D.J., Cantwell, B.A., The DNA sequence of the gene and genetic control sites for the excreted B. subtilis enzyme βglucanase, Nucleic Acids Research , 12, (13), 1984, p5355-5367 Journal Article, 1984

Riley M, O'Reilly C, McConnell D, Physical map of Salmonella typhimurium LT2 DNA in the vicinity of the proA gene., Journal of bacteriology, 157, (2), 1984, p655-7 Journal Article, 1984

Cantwell BA, McConnell DJ, Molecular cloning and expression of a Bacillus subtilis beta-glucanase gene in Escherichia coli., Gene, 23, (2), 1983, p211-9 Journal Article, 1983

Ortlepp SA, Ollington JF, McConnell DJ, Molecular cloning in Bacillus subtilis of a Bacillus licheniformis gene encoding a thermostable alpha amylase., Gene, 23, (3), 1983, p267-76 Journal Article, 1983

Ryan T, McConnell DJ, Physical mapping of hybrid bacteriophage T7/T3 RNA polymerase genes., Journal of virology, 43, (3), 1982, p844-58 Journal Article, 1982

Yeats SM, Schwarz TF, Ryan TP, Garner I, Hayward RS, McConnell DJ, A possible role in transcription for the single-stranded DNA binding protein of bacteriophage T7., Molecular & general genetics : MGG, 183, (1), 1981, p187-91 Journal Article, 1981

Schwarz TF, Yeats SM, Connolly P, McConnell DJ, Altered transcriptional termination in a rifampicin-resistant mutant of Escherichia coli which inhibits the growth of bacteriophage T7., Molecular & general genetics : MGG, 183, (1), 1981, p181-6 Journal Article, 1981

Mahon GA, McWilliam P, Gordon RL, McConnell DJ, The time course of transcription., Journal of theoretical biology, 87, (3), 1980, p483-515 Journal Article, 1980

West RW, McConnell D, Rodriguez RL, Isolation of E.coli promoters from the late region of bacteriophage T7 DNA., Molecular & general genetics : MGG, 180, (2), 1980, p439-47 Journal Article, 1980

Gordon RL, Humphries P, McConnell DJ, Restriction enzyme cleavage mapping of T7 virus early region., Molecular & general genetics : MGG, 162, (3), 1978, p329-39 Journal Article, 1978

Humphries P, Gordon RL, McConnell DJ, Connolly P, Endonuclease R. Hind fragments of T7 DNA., Virology, 58, (1), 1974, p25-31 Journal Article, 1974

Humphries P, McConnell DJ, Gordon RL, A procedure for the rapid purification of Escherichia coli deoxyribonucleic acid-dependent ribonucleic acid polymerase., The Biochemical journal, 133, (1), 1973, p201-3 Journal Article, 1973