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Dr. Elizabeth Heron
Assistant Professor, Psychiatry

Publications and Further Research Outputs

Peer-Reviewed Publications

Lombard Kim, Nolan Clodagh & Heron Elizabeth A., Refining the psychometirc properties of the Trinity Student Occupational Performance Profile - A self-report measure of occupational difficulties within the student role, British Journal of Occupational Therapy, 2022, p1 - 10 Journal Article, 2022 DOI

Chapter 2 Schizophrenia genomics in, editor(s)Evangelia Eirini Tsermpini, Martin Alda, and George P. Patrinos , Psychiatric Genomics, 2022, [Ryan NM, Ormond C, Brady P, Heron EA, Corvin A] Book Chapter, 2022 DOI

Lombard, Nolan & Heron, A Scoping Review of the Use of Rasch Analysis Methodology to strengthen Self-Report Occupational Therapy Mental Health Measures, Occupational Therapy in Mental Heath, 2022 Journal Article, 2022 DOI

McGrath J, Cawley B, McTiernan D, Marques L, Goncerz E, Heron EA, Madden J, Bond L, Quinn C, Mulholland K, Dowling B , Service user satisfaction with care in a specialist service for young people with attention deficit hyperactivity disorder., Irish Journal of Psychological Medicine, 2022 Journal Article, 2022 DOI

Ryan N, Ormond C, Chang YC, Contreras J, Raventos H, Gill M, Heron E, Mathews CA, & Corvin A, Identity-by-descent analysis of a large Tourette's syndrome pedigree from Costa Rica implicates genes involved in neuronal development and signal transduction, Molecular Psychiatry, 2022 Journal Article, 2022

Forde E, Leech M, Robert C, Heron E, Marignol L, Influence of Inter-Observer Delineation Variability on Radiomic Features of the Parotid Gland, Physica Medica, (82), 2021, p240 - 248 Journal Article, 2021 DOI

O'Toole SA, Huang Y, Norris L, Power Foley M, Shireen R, McDonald S, Kamran W, Ibrahim N, Ward M, Thompson C, Murphy C, D'Arcy T, Farah N, Heron E, O'Leary JJ, Abu Saadeh F, Gleeson N., HE4 and CA125 as preoperative risk stratifiers for lymph node metastasis in endometrioid carcinoma of the endometrium: A retrospective study in a cohort with histological proof of lymph node status., Gynecologic oncology, 2021 Journal Article, 2021 DOI

Ormond C, Ryan NM, Corvin A, Heron EA., Converting single nucleotide variants between genome builds: from cautionary tale to solution., Briefings in bioinformatics, 2021 Journal Article, 2021 DOI

Thekiso TB, McLoughlin DM, Hartnett Y, Casey S, Orji A, Heron EA, Rush G, Kennedy N., Outcome of First-admission Depression Treated in a Specialized Mood Disorders Service., Journal of psychiatric practice, 26, (6), 2020, p461-471 Journal Article, 2020 DOI

Foley C, Heron EA, Harold D, Walters J, Owen M, O'Donovan M, Sebat J, Kelleher E, Mooney C, Durand A, Pinto C, Cormican P, Morris D, Donohoe G, Gill M, Gallagher L, Corvin A., Identifying schizophrenia patients who carry pathogenic genetic copy number variants using standard clinical assessment: retrospective cohort study., The British journal of psychiatry : the journal of mental science, 216, (5), 2020, p275-279 Journal Article, 2020 DOI TARA - Full Text

Kelleher E, McNamara P, Dunne J, Fitzmaurice B, Heron EA, Whitty P, Walsh R, Mooney C, Hogan D, Conlon N, Gill M, Vincent A, Doherty CP, Corvin A., Prevalence of N-Methyl-d-Aspartate Receptor antibody (NMDAR-Ab) encephalitis in patients with first episode psychosis and treatment resistant schizophrenia on clozapine, a population based study., Schizophrenia research, 222, 2020, p455-461 Journal Article, 2020 DOI

Sullivan, M.O. and Gallagher, L. and Heron, E.A., Gaining Insights into Aggressive Behaviour in Autism Spectrum Disorder Using Latent Profile Analysis, Journal of Autism and Developmental Disorders, 2019 Journal Article, 2019 DOI

Connolly, S. and Anney, R. and Gallagher, L. and Heron, E.A., Evidence of Assortative Mating in Autism Spectrum Disorder, Biological Psychiatry, 86, (4), 2019, p286-293 Journal Article, 2019 DOI

Connolly, S., Anney, R., Gallagher, L., Heron, E.A., A genome-wide investigation into parent-of-origin effects in autism spectrum disorder identifies previously associated genes including SHANK3, European Journal of Human Genetics, 25, (2), 2017, p234-239 Journal Article, 2017 DOI

Falk, M.G., Alston, C.L., McGrory, C.A., (...), Pettitt, A.N., Mengersen, K.L., Recent Bayesian approaches for spatial analysis of 2-D images with application to environmental modelling, Environmental and Ecological Statistics, 2015 Journal Article, 2015 DOI

Kenny EM, Cormican P, Furlong S, Heron E, Kenny G, Fahey C, Kelleher E, Ennis S, Tropea D, Anney R, Corvin AP, Donohoe G, Gallagher L, Gill M, Morris DW, Excess of rare novel loss-of-function variants in synaptic genes in schizophrenia and autism spectrum disorders., Molecular psychiatry, 19, 2014, p872-879 Journal Article, 2014 TARA - Full Text DOI

Merikangas AK, Segurado R, Cormican P, Heron EA, Anney RJ, Moore S, Kelleher E, Hargreaves A, Anderson-Schmidt H, Gill M, Gallagher L, Corvin A., The phenotypic manifestations of rare CNVs in schizophrenia., Schizophrenia Research, 158, (1-3), 2014, p255 - 260 Journal Article, 2014 DOI

Heron, E.A., Cormican, P., Donohoe, G., O'Neill, F.A., Kendler, K.S., Riley, B.P., Gill, M., Corvin, A.P., Morris, D.W., No evidence that runs of homozygosity are associated with schizophrenia in an Irish genome-wide association dataset, Schizophrenia Research, 154, (1-3), 2014, p79-82 Journal Article, 2014 DOI TARA - Full Text

Connolly, S and Heron, E.A., Review of statistical methodologies for the detection of parent-of-origin effects in family trio genome-wide association data with binary disease traits., Briefings in Bioinformatics, 2014 Journal Article, 2014 DOI TARA - Full Text

Merikangas AK, Segurado R, Heron EA, Anney RJ, Paterson AD, Cook EH, Pinto D, Scherer SW, Szatmari P, Gill M, Corvin AP, Gallagher L., The phenotypic manifestations of rare genic CNVs in autism spectrum disorder., Molecular Psychiatry, 2014, p1-7 Journal Article, 2014 TARA - Full Text DOI

Thekiso, T.B., Heron, E.A., Masood, B., Murphy, M., McLoughlin, D.M., Kennedy, N., Mauling of the "celtic Tiger": Clinical characteristics and outcome of first-episode depression secondary to the economic recession in Ireland, Journal of Affective Disorders, 151, (2), 2013, p455-460 Journal Article, 2013 DOI

Anney R, Klei L, Pinto D, Almeida J, Bacchelli E, Baird G, Bolshakova N, Bölte S, Bolton PF, Bourgeron T, Brennan S, Brian J, Casey J, Conroy J, Correia C, Corsello C, Crawford EL, de Jonge M, Delorme R, Duketis E, Duque F, Estes A, Farrar P, Fernandez BA, Folstein SE, Fombonne E, Gilbert J, Gillberg C, Glessner JT, Green A, Green J, Guter SJ, Heron EA, Holt R, Howe JL, Hughes G, Hus V, Igliozzi R, Jacob S, Kenny GP, Kim C, Kolevzon A, Kustanovich V, Lajonchere CM, Lamb JA, Law-Smith M, Leboyer M, Le Couteur A, Leventhal BL, Liu XQ, Lombard F, Lord C, Lotspeich L, Lund SC, Magalhaes TR, Mantoulan C, McDougle CJ, Melhem NM, Merikangas A, Minshew NJ, Mirza GK, Munson J, Noakes C, Nygren G, Papanikolaou K, Pagnamenta AT, Parrini B, Paton T, Pickles A, Posey DJ, Poustka F, Ragoussis J, Regan R, Roberts W, Roeder K, Roge B, Rutter ML, Schlitt S, Shah N, Sheffield VC, Soorya L, Sousa I, Stoppioni V, Sykes N, Tancredi R, Thompson AP, Thomson S, Tryfon A, Tsiantis J, Van Engeland H, Vincent JB, Volkmar F, Vorstman JA, Wallace S, Wing K, Wittemeyer K, Wood S, Zurawiecki D, Zwaigenbaum L, Bailey AJ, Battaglia A, Cantor RM, Coon H, Cuccaro ML, Dawson G, Ennis S, Freitag CM, Geschwind DH, Haines JL, Klauck SM, McMahon WM, Maestrini E, Miller J, Monaco AP, Nelson SF, Nurnberger JI, Oliveira G, Parr JR, Pericak-Vance MA, Piven J, Schellenberg GD, Scherer SW, Vicente AM, Wassink TH, Wijsman EM, Betancur C, Buxbaum JD, Cook EH, Gallagher L, Gill M, Hallmayer J, Paterson AD, Sutcliffe JS, Szatmari P, Vieland VJ, Hakonarson H, Devlin B, Individual common variants exert weak effects on the risk for autism spectrum disorderspi., Human molecular genetics, 21, (21), 2012, p4781-92 Journal Article, 2012 TARA - Full Text DOI

O'Dushlaine C, Kenny E, Heron E, Donohoe G, Gill M, Morris D, Consortium IS, Corvin A, Molecular pathways involved in neuronal cell adhesion and membrane scaffolding contribute to schizophrenia and bipolar disorder susceptibility., Molecular Psychiatry, 16, (3), 2011, p286-292 Journal Article, 2011 DOI TARA - Full Text

Heron Elizabeth A, O'Dushlane C, Segurado R, Gallagher L, Gill M., Exploration of empirical Bayes hierarchical modeling for the analysis of genome-wide association study data., Oxford Journal Mathematics & Physical Sciences Biostatistics, 12, (3), 2011, p445-461 Journal Article, 2011 TARA - Full Text

Bridges M, Heron E, O'Dushlaine, Segurado R, The International Schizophrenia Consortium (ISC), Morris DW, Corvin A, Gill M, Pinto C. , Genetic Classification of Populations using Supervised Learning., PLos One, 6, (5), 2011, pe14802 Journal Article, 2011 TARA - Full Text DOI

Heron, E.A., Walsh, C., Bayesian Discrete Latent Spatial Modelling of Crack Initiation in Orthopaedic Hip Replacement Bone Cement, Journal of Applied Statistics, 37, (7), 2010, p1153 - 1171 Journal Article, 2010 URL

Nwachukwu I, Crumlish N, Heron EA, Gill M, The Irish Mental Health Act 2001: Impact on involuntary admissions in a community mental health service in Dublin, The Psychiatrist, 34, 2010, p436-440 Journal Article, 2010 DOI

Pinto, D, Pagnamenta, AT, Klei, L, Anney, R, Merico, D, Regan, R, Conroy, J, Magalhaes, TR, Correia, C, Abrahams, BS, Almeida, J, Bacchelli, E, Bader, GD, Bailey, AJ, Baird, G, Battaglia, A, Berney, T, Bolshakova, N, Bolte, S, Bolton, PF, Bourgeron, T, Brennan, S, Brian, J, Bryson, SE, Carson, AR, Casallo, G, Casey, J, Chung, BHY, Cochrane, L, Corsello, C, Crawford, EL, Crossett, A, Cytrynbaum, C, Dawson, G, de Jonge, M, Delorme, R, Drmic, I, Duketis, E, Duque, F, Estes, A, Farrar, P, Fernandez, BA, Folstein, SE, Fombonne, E, Freitag, CM, Gilbert, J, Gillberg, C, Glessner, JT, Goldberg, J, Green, A, Green, J, Guter, SJ, Hakonarson, H, Heron, EA, Hill, M, Holt, R, Howe, JL, Hughes, G, Hus, V, Igliozzi, R, Kim, C, Klauck, SM, Kolevzon, A, Korvatska, O, Kustanovich, V, Lajonchere, CM, Lamb, JA, Laskawiec, M, Leboyer, M, Le Couteur, A, Leventhal, BL, Lionel, AC, Liu, XQ, Lord, C, Lotspeich, L, Lund, SC, Maestrini, E, Mahoney, W, Mantoulan, C, Marshall, CR, McConachie, H, McDougle, CJ, McGrath, J, McMahon, WM, Merikangas, A, Migita, O, Minshew, NJ, Mirza, GK, Munson, J, Nelson, SF, Noakes, C, Noor, A, Nygren, G, Oliveira, G, Papanikolaou, K, Parr, JR, Parrini, B, Paton, T, Pickles, A, Pilorge, M, Piven, J, Ponting, CP, Posey, DJ, Poustka, A, Poustka, F, Prasad, A, Ragoussis, J, Renshaw, K, Rickaby, J, Roberts, W, Roeder, K, Roge, B, Rutter, ML, Bierut, LJ, Rice, JP, Salt, J, Sansom, K, Sato, D, Segurado, R, Sequeira, AF, Senman, L, Shah, N, Sheffield, VC, Soorya, L, Sousa, I, Stein, O, Sykes, N, Stoppioni, V, Strawbridge, C, Tancredi, R, Tansey, K, Thiruvahindrapduram, B, Thompson, AP, Thomson, S, Tryfon, A, Tsiantis, J, Van Engeland, H, Vincent, JB, Volkmar, F, Wallace, S, Wang, K, Wang, ZZ, Wassink, TH, Webber, C, Weksberg, R, Wing, K, Wittemeyer, K, Wood, S, Wu, J, Yaspan, BL, Zurawiecki, D, Zwaigenbaum, L, Buxbaum, JD, Cantor, RM, Cook, EH, Coon, H, Cuccaro, ML, Devlin, B, Ennis, S, Gallagher, L, Geschwind, DH, Gill, M, Haines, JL, Hallmayer, J, Miller, J, Monaco, AP, Nurnberger, JI, Paterson, AD, Pericak-Vance, MA, Schellenberg, GD, Szatmari, P, Vicente, AM, Vieland, VJ, Wijsman, EM, Scherer, SW, Sutcliffe, JS, Betancur, C, Functional impact of global rare copy number variation in autism spectrum disorders, NATURE, 466, 2010, p368-372 Journal Article, 2010 TARA - Full Text

Anney R, Klei L, Pinto D, Regan R, Conroy J, Magalhaes TR, Correia C, Abrahams BS, Sykes N, Pagnamenta AT, Almeida J, Bacchelli E, Bailey AJ, Baird G, Battaglia A, Berney T, Bolshakova N, Bölte S, Bolton PF, Bourgeron T, Brennan S, Brian J, Carson AR, Casallo G, Casey J, Chu S, Cochrane L, Corsello C, Crawford EL, Crossett A, Dawson G, de Jonge M, Delorme R, Drmic I, Duketis E, Duque F, Estes A, Farrar P, Fernandez BA, Folstein SE, Fombonne E, Freitag CM, Gilbert J, Gillberg C, Glessner JT, Goldberg J, Green A, Green J, Guter SJ, Hakonarson H, Heron EA, Hill M, Holt R, Howe JL, Hughes G, Hus V, Igliozzi R, Kim C, Klauck SM, Kolevzon A, Korvatska O, Kustanovich V, Lajonchere CM, Lamb JA, Laskawiec M, Leboyer M, Le Couteur A, Leventhal BL, Lionel AC, Liu XQ, Lord C, Lotspeich L, Lund SC, Maestrini E, Mahoney W, Mantoulan C, Marshall CR, McConachie H, McDougle CJ, McGrath J, McMahon WM, Melhem NM, Merikangas A, Migita O, Minshew NJ, Mirza GK, Munson J, Nelson SF, Noakes C, Noor A, Nygren G, Oliveira G, Papanikolaou K, Parr JR, Parrini B, Paton T, Pickles A, Piven J, Posey DJ, Poustka A, Poustka F, Prasad A, Ragoussis J, Renshaw K, Rickaby J, Roberts W, Roeder K, Roge B, Rutter ML, Bierut LJ, Rice JP, Salt J, Sansom K, Sato D, Segurado R, Senman L, Shah N, Sheffield VC, Soorya L, Sousa I, Stoppioni V, Strawbridge C, Tancredi R, Tansey K, Thiruvahindrapduram B, Thompson AP, Thomson S, Tryfon A, Tsiantis J, Van Engeland H, Vincent JB, Volkmar F, Wallace S, Wang K, Wang Z, Wassink TH, Wing K, Wittemeyer K, Wood S, Yaspan BL, Zurawiecki D, Zwaigenbaum L, Betancur C, Buxbaum JD, Cantor RM, Cook EH, Coon H, Cuccaro ML, Gallagher L, Geschwind DH, Gill M, Haines JL, Miller J, Monaco AP, Nurnberger JI, Paterson AD, Pericak-Vance MA, Schellenberg GD, Scherer SW, Sutcliffe JS, Szatmari P, Vicente AM, Vieland VJ, Wijsman EM, Devlin B, Ennis S, Hallmayer J, A genomewide scan for common alleles affecting risk for autism., Human molecular genetics, 19, (20), 2010, p4072-4082 Journal Article, 2010 DOI TARA - Full Text

O'Dushlaine C., Kenny E., Heron E.A., Segurado R., Gill M,, Morris D.W., Corvin A. , The SNP ratio test: pathway analysis of genome-wide association datasets., Bioinformatics, 25, (20), 2009, p2762 - 2763 Journal Article, 2009 TARA - Full Text DOI

Heron, E.A., Walsh, C., A continuous latent spatial model for crack initiation in bone cement, Journal of the Royal Statistical Society Series C (Applied Statistics), 57, 2008, p25 - 42 Journal Article, 2008

Tang, S., Heron, E.A., Bayesian inference for a stochastic logistic model with switching points, Ecological Modelling , 219, (1-2), 2008, p153 - 169 Journal Article, 2008

Finkenstädt, B., Heron, E.A., Komorowski, M., Edwards, K., Tang, S., Harper, C.V., Davis, J.R., White, M.R., Millar, A.J., Rand, D.A., Reconstruction of transcriptional dynamics from gene reporter data using differential equations, Bioinformatics, 15, (24), 2008, p2901 - 2907 Journal Article, 2008

Heron, E.A., Finkenstädt, B. and Rand, D.A. , Bayesian inference for dynamic transcriptional regulation; the Hes1 system as a case study, Bioinformatics, 23, (19), 2007, p2596 - 2603 Journal Article, 2007

Non-Peer-Reviewed Publications

C Ormond, N Ryan, W Byerley, A Corvin, E Heron, T16. A Bayesian framework to model pedigree-based causality using next-generation sequencing data, European Neuropsychopharmacology , Abstracts of the World Congress of Psychiatric Genetics, September 13-17, 63, 2022, ppe176 - e177 Poster, 2022

C Ormond, NM Ryan, W Byerley, A Corvin, EA Heron, A Bayesian framework to model co-segregation in pedigrees using next-generation sequencing data, HUMAN HEREDITY, 50th European Mathematical Genetics Meeting, Cambridge, April 21-22, 2022, 87, Karger, 2022, pp17 - 17 Oral Presentation, 2022

Niamh M. Ryan Cathal Ormond Kazima Bulaeva Elizabeth A Heron Michael Gill Aiden Corvin , TH75. SEQUENCING STUDY OF A CONSANGUINEOUS PEDIGREE WITH A HIGH LOAD OF SCHIZOPHRENIA, European Neuropsychopharmacology, 2021 Poster, 2021

Cathal Ormond Niamh M. Ryan William Byerley Elizabeth A Heron Michael Gill Aiden Corvin , TU74. A CO-SEGREGATION ANALYSIS OF ULTRA-RARE VARIANTS IN FAMILIES MULTIPLY AFFECTED BY SCHIZOPHRENIA USING WHOLE GENOME SEQUENCING, European Neuropsychopharmacology, 2021 Poster, 2021

C Ormond, A Corvin, E Heron, A Comparison of Two Software Tools for Disease-Gene Prioritization for Family-Based Sequencing Studies, Human Heredity, 84, Karger, 2020, pp218 - 218 Poster, 2020

N Ryan, L Gallagher, E Heron, SA22INVESTIGATING PARENT-OF-ORIGIN EFFECTS IN AUTISM SPECTRUM DISORDER USING NEXT GENERATION SEQUENCING DATA, European Neuropsychopharmacology , XXVIth World Congress of Psychiatric Genetics (WCPG) , Glasgow, Scotland, 11 - 15 October 2018, 2019, ppS1199 - S1200 Poster, 2019

Ryan, Niamh & Ormond, Cathal & Arsalan, Arsalan & Byerley, William & Ayub, Muhammad & Matthews, Carol & Heron, Elizabeth & Gill, Michael & Corvin, Aiden. , S97DETECTION OF RARE INHERITED CNVS ASSOCIATED WITH PSYCHIATRIC ILLNESS FROM FAMILY WHOLE GENOME SEQUENCING DATA., European Neuropsychopharmacology., 2019 Poster, 2019

D Smajlagic, S Connolly, H Hakonarson, I Waldman, J Elia, E Heron, J Haavik, S Johansson, T Zayats,, SU4 - GENOME-WIDE EXAMINATION OF PARENT-OF-ORIGIN EFFECTS IN CHILDREN WITH ATTENTION DEFICIT HYPERACTIVITY DISORDER, European Neuropsychopharmacology, 29, 2019, ppS888 - S889 Poster, 2019

Corfield, Elizabeth & Smajlagic, Dinka & Connoly, Siobhan & Havdahl, Alexandra & Tesli, Martin & Waldman, Irwin & Elia, Josephine & Heron, Elizabeth & Reichborn-Kjennerud, Ted & Haavik, Jan & Johansson, Stefan & Zayats, Tetyana. , S1PARENT-OF-ORIGIN AND MATERNAL EFFECTS IN ATTENTION DEFICIT HYPERACTIVITY DISORDER. , European Neuropsychopharmacology, , 2019 Poster, 2019

Niamh Ryan, Louise Gallagher, Elizabeth Heron, Investigating Parent-of-Origin Effects in Autism Spectrum Disorders Using Next Generation Sequencing Data, European Neuropsychopharmacology, World Congress of Psychiatric Genetics, Glasgow, Scotland, 11-15 October 2018, 2018 Poster, 2018 URL DOI

Merikangas, A.K., Segurado, R., Kelleher, E., Hogan, D., Delaney, C., Gill, M., Gallagher, L., Corvin, A.P., and Heron, E.A. , Parental age, birth order and neurodevelopmental disorders, 1826, 2016, - Miscellaneous, 2016 DOI

S. Connolly, R. Anney, L. Gallagher, E. Heron, Investigation of Assortative Mating in Autism Spectrum Disorders, Human Heredity, 43rd European Mathematical Genetics Meeting (EMGM) 2015, Brest, France, April 16-17, 2015, edited by Emmanuelle Génin, Karen Rouault , 79, 2015, pp28 - 52 Poster, 2015 URL DOI

AK Merikangas, EA Heron, R Anney, AP Corvin, L Gallagher, Investigating the association between rare copy number variation and developmental anomalies in autism spectrum disorders, Genetic Epidemiology , Nineteenth annual meeting of the International Genetic Epidemiology Society, 34, (8), 2010, pp929 - 929 Poster, 2010

Research Expertise


Bayesian Inference; Bioinformatics; Biostatistical methods; Genetics; MATHEMATICAL MODELLING; Statistics



Fellow of the Royal Statistical Society 2005 – Present