Professor Brian O'Connell

Professor Brian O'Connell

Professor, Dental Science

Dean of Health Sciences, Fac Office - Faculty of Health Sciences

3531 6127240http://people.tcd.ie/boconne

Publications and Further Research Outputs

  • Al-Awadhi, E.A., Garvey, T.M., Alhag, M., Claffey, N.M., O'Connell, B., Efficacy of the Nance appliance as an anchorage-reinforcement method, American Journal of Orthodontics and Dentofacial Orthopedics, 147, (3), 2015, p330-338Journal Article, 2015
  • Mcauliffe, P., Kim, J.H., Diamond, D., Lau, K.T., O'Connell, B.C., A sleep bruxism detection system based on sensors in a splint - pilot clinical data, Journal of Oral Rehabilitation, 42, (1), 2015, p34-39Journal Article, 2015
  • Meaney S, Connell BO, Elfadil S, Allen F, A qualitative investigation into patients' perspectives on edentulousness., Gerodontology, 34, (1), 2017, p79 - 85Journal Article, 2017, DOI
  • Dagg, H., O'Connell, B., Claffey, N., Byrne, D. and Gorman, C., The influence of some different factors on the accuracy of shade selection., Journal of Oral Rehabilitation, 31, 2004, p900 - 904Journal Article, 2004
  • Michael O'Sullivan, Brian C O'Connell, Multidisciplinary management of hypodontia , Prim Dent J, 6, (1), 2017, p62 - 73Journal Article, 2017
  • Xu, YY, Histatin 3-Mediated Killing of Candida Albicans: Effect of Extracellular Salt Concentration on Binding and Internalization, Antimicrobial Agents and Chemotherapy, 43, 1999, p2256 - 2262Journal Article, 1999
  • O'Connell, B., Tabak, L.A., and Ramasubbu, N., The influence of flanking sequences on O-glycosylation, Biochem. Biophys. Res. Commun., 180, 1991, p1024 - 1024Journal Article, 1991
  • O'Connell, B.C., Hagen, F., and Tabak, L.A., The influence of flanking amino acid sequence on O-glycosylation by UDPGalNAc: Polypeptide N-acetylgalactosaminyltransferase, J. Biol. Chem., 267, 1992, p25010 - 25018Journal Article, 1992
  • O'Connell, B.C., and Tabak, L.A., Separation of glycopeptides from in vitro O-glycosylation reactions using C18 cartridges, Anal. Biochem., 210, 1993, p423 - 425Journal Article, 1993
  • O'Connell, B.C., and Tabak, L.A., A comparison of serine and threonine O-glycosylation by UDPGalNAc: Polypeptide N-acetylgalactosaminyltransferase, J. Dent. Res., 72, 1993, p1554 - 1558Journal Article, 1993
  • Salivary Gland-Specific Gene Expression in, U.S./Latin American Workshop on Salivary Research, Albuquerque, C&A Press, 1993, pp66 - 75, [O'Connell, B.C. and Tabak, L.A.]Book Chapter, 1993
  • Mastrangeli, A.M., O'Connell, B.C., Fox, P.C., Aladib, W., Baum, B.J., and Crystal, R.G., In vivo gene transfer to rat salivary gland, Am. J. Physiol., 266, 1994, pG1146 - G1155Journal Article, 1994
  • Baum, B.J. and O'Connell, B.C., The Impact of Gene Therapy on Dentistry, JADA, 126, 1995, p179 - 189Journal Article, 1995
  • O'Connell, B.C., Ten Hagen, K.G., Lazowski, K.W., Tabak, L.A. and Baum, B.J., Facilitated DNA Transfer to Rat Submandibular Gland in Vivo and GRP Gene Regulation, Am. J. Physiol., 268, 1995, pG1074 - G1078Journal Article, 1995
  • Sharma, A., O'Connell, B.C., Tabak, L.A. and Bedi, G.S., Expression of a Functional Rat Salivary Cystatin S Polypeptide in Escherichia coli, Arch. Oral. Biol., 40, (7), 1995, p639 - 644Journal Article, 1995
  • Wu, A.J., Chen, Z.J., Tsokos, M., O'Connell, B.C., Ambudkar, I.S. and Baum, B.J., Interferon- induced Cell Death in a Cultured Human Salivary Gland Cell Line, J. Cell Physiol, 167, 1996, p297 - 304Journal Article, 1996
  • Adesanya, M.R., Redman, R.S., Baum, B.J. and O'Connell, B.C., Acute Inflammatory Response in Adenovirus-mediated Gene Transfer to Rat Salivary Glands, Hum. Gene Ther, 7, (9), 1996, p1085 - 1093Journal Article, 1996
  • Delporte, C., O'Connell, B.C., He, X., Ambudkar, I.S., Agre, P. and Baum, B.J., Adenovirus-mediated Expression of Aquaporin 5 in Epithelial Cells, J. Biol. Chem, 271, (36), 1996, p22070 - 22075Journal Article, 1996
  • Kagami, H., O'Connell, B.C. and Baum B.J., Evidence for the Systemic Delivery of a Transgene Product from Salivary Glands, Hum. Gene Ther, 7, 1996, p2177 - 2184Journal Article, 1996
  • O'Connell, B.C., Xu, T., Walsh, T.J., Sein, T., Mastrangeli, A., Crystal, R.G., Oppenheim, F.G. and Baum, B.J., Transfer of a Gene Encoding the Anticandidal Protein Histatin 3 to Salivary Glands, Hum. Gene Ther, 7, 1996, p2255-Journal Article, 1996
  • Delporte, C., O'Connell, B.C., He, X., Lancaster, H.E., O'Connell, A.C., Agre, P. and Baum, B.J., Increased Fluid Secretion Following Transfer of the Aquaporin-1 cDNA to Irradiated Rat Salivary Glands, Proc. Natl. Acad. Sci. USA 94, 1997, p3268 - 3273Journal Article, 1997
  • Gene Transfer to Salivary Glands in, Studies in Stomatology and Craniofacial Biology, IOS Press, 1997, pp615 - 631, [O'Connell, B.C. and Baum, B.J.]Book Chapter, 1997
  • Lillibridge, C.D., and O'Connell, B.C., In Human Salivary Cells, Overexpression of E2F1 Overcomes an IFN-- and TNF--Induced Growth Arrest But Does Not Result in Complete Mitosis, J. Cell. Physiol., 172, 1997, p343 - 350Journal Article, 1997
  • Delporte, C., Panyutin, I.G., Sedelnikova, O.A., Lillibridge, C.D., O'Connell, B.C. and Baum, B.J., Triplex Forming Oligonucleotides Can Modulate Aquaporin-5 Gene Expression in Epithelial cells, Antisense and Nucleic Acid Drug Development, 7, 1997, p523 - 529Journal Article, 1997
  • Delporte, C., Miller, G., Kagami, H., Lillibridge, C.D., O'Connell, B.C., Atkinson, J.C. and Baum, B.J., Safety of Salivary Gland-Administered Replication-Deficient Recombinant Adenovirus in Rats, J. Oral Pathol. Med., 27, 1997, p34 - 38Journal Article, 1997
  • O'Connell, B.C., Redman, R.S. and Zheng, C., In Vivo Use of Adenoviral Vectors: Effects on Salivary Gland Structure, Eur. J Morphol., 36, 1998, p55 - 80Journal Article, 1998
  • Kagami, H., Atkinson, J.A., Handelman, B., Yu, S., Baum, B. and O'Connell, B.C., Repetitive Adenovirus Administration to Parotid Gland: Role of Immunological Barriers and Induction of Oral Tolerance, Hum. Gene Ther., 9, 1998, p305 - 313Journal Article, 1998
  • O'Connell, B.C., Lillibridge, C.D., Ambudkar, I. and Kruse, D., Somatic Gene Transfer to Salivary Glands, Ann. NY Acad. Sci., 842, 1998, p171 - 180Journal Article, 1998
  • Mannes, A.J., Caudle, R.M., O'Connell, B.C. and Iadarola, M.J., Adenoviral Gene Transfer to Spinal Cord Neurons: Intrathecal vs. Intraparenchymal Administration, Brain Res., 793, (1-2), 1998, p1 - 6Journal Article, 1998
  • O'Connell, A.C., Lillibridge, C.D., Zheng, C., Baum, B.J., O'Connell, B.C. and Ambudkar, I.S., -Irradiation-Induced Cell Cycle Arrest and Cell Death in a Human Submandibular Gland Cell Line: Effect of E2F1 Expression, J. Cell Physiol, 177, (2), 1998, p264 - 273Journal Article, 1998
  • Zheng, C., Hoffman, M.P., McMillan, T., Kleinman, H.K. and O'Connell, B.C., Growth Factor Regulation of the Amylase Promoter in Differentiating Salivary Gland Acinar Cells, J. Cell Physiol., 177, 1998, p628 - 635Journal Article, 1998
  • DeNichilo, M.O., Katz, B., O'Connell, B.C. and Yamada, K.M., Adenovirus-Mediated Gene Delivery of pp125FAK into Cultured Human Macrophages Deficient in This Protein Directs p50CSK Localization to Focal Contacts and Regulated MAP Kinase, J. Cell Physiol., 178, 1999, p164 - 172Journal Article, 1999
  • Baum, B.J., Atkinson, J., Baccaglini, L., Berkman, M., Brahim, J., Davis, V., Lancaster, H., Marmary, Y., O'Connell, A., O'Connell, B., Wang, S., Xu, Y., Yamagishi, H. and Fox, P., The Mouth is a Gateway to the Body: Gene Therapy in 21st Century Dental Practice, CDA Journal, 26, (6), 1998, p455 - 460Journal Article, 1998
  • Sommer, B., Kuznetsov, S.A., Gehron Robey, P., O'Connell, B.C., Cristiano. R.J. and Young, M.F., Efficient Gene Transfer into Normal Human Skeletal Cells Using Recombinant Adenovirus and Conjugated Adenovirus-DNA Complexes, Calc. Tissue Int., 64, 1999, p45 - 49Journal Article, 1999
  • Brennan, M.T., O'Connell, B.C., Rams, T.E. and O'Connell, A.C., Management of Gingival Overgrowth Associated with Generalized Enamel Defects in a Child, J Clin Pediatr Dent, 23, (2), 1999, p97 - 102Journal Article, 1999
  • Schönherr, E., O'Connell, B.C., Schittny, J., Robenek, H., Fastermann, D., Fisher, L.W., Plenz, G., Vischer, P., Young, M.F. and Kresse, H., Paracrine or virus-mediated induction of decorin expression by endothelial cells contributes to tube formation and prevention of apoptosis in collagen lattices, Eur. J. Cell Biol., 78, 1999, p44 - 45Journal Article, 1999
  • Wang, S., Baum, B.J., Kagami, H., Zheng, C., O'Connell, B.C., and Atkinson, J.C., Effect of clodronate on macrophage depletion and adenoviral-mediated transgene expression in salivary glands, J. Oral Pathol. Med., 28, 1999, p145 - 151Journal Article, 1999
  • Wang, W., O'Connell, B.C., Dykeman, R., Sakai., Delporte, C., Swaim, W., Zhu, X., Birnbaumer, L. and Ambudkar, I., Cloning of TRP1b isoform from rat brain: immunodetection and localization of the endogenous Trp 1 protein, Am. J. Physiol, 45, (5), 1999, pC969 - C979Journal Article, 1999
  • Baum, B.J. and O'Connell, B.C., The need to introduce gene therapy to the dental curriculum, Eur J Dent Educ, 3, 1999, p49 - 51Journal Article, 1999
  • Baum, B.J. and O'Connell, B.C., Vivo Gene Transfer to Salivary Glands, Crit. Rev. Oral Biol.Med., 10, (3), 1999, p276 - 283Journal Article, 1999
  • Connell, A.C., Baccaglini, L., Fox, P.C., O'Connell, B.C., Kenshalo, D., Oweisy, H., Hoque, A.T.M., Sun, D., Herscher, L.L., Braddon, V.R., Delporte, C. and Baum, B., Efficacy of Adenovirus-mediated Transfer of the Human Aquaporin 1 cDNA to Irradiated Parotid Glands of Non-human Primates, Cancer Gene Ther, 6, (6), 1999, p505 - 513Journal Article, 1999
  • Hoque, A.T.M.S., Liu, X., Kagami, H. Swaim, W.D., Wellner, R.B., O'Connell, B.C., Ambudkar, I.S., and Baum, B.J., Construction and function of a recombinant adenovirus encoding a human aquaporin 1-green fluorescence protein fusion product, Cancer Gene Ther., 7, 2000, p476 - 485Journal Article, 2000
  • Zheng, C., Baum, B.J., Iadarola, M.J. and O'Connell, B.C., Genomic Integration and Long Term Expression by a Modified Adenoviral Vector, Nature Biotechnol, 18, (2), 2000, p176 - 180Journal Article, 2000
  • He, L., Liu, J., Collins, I., Sanford, S., O'Connell, B.C., Benham, C.J., and Levens, D., Loss of FBP Function Arrests Cell Proliferation and Extinguishes c-myc Expression, EMBO J, 19, (5), 2000, p1034 - 1044Journal Article, 2000
  • Baum, B.J., Goldsmith, C.M., Hoque, A.T.M., Wellner, R.B., Baccaglini, L., Ding, C., Yamano, S., Zheng, C., Aframian, D.J. and O'Connell, B.C., Salivary Glands as a Model for Craniofacial Applications of Gene Transfer, Int J. Oral & Maxillofac Surg, 29, 2000, p163 - 166Journal Article, 2000
  • Zheng, C., Goldsmith, C.M., O'Connell, B.C. and Baum, B.J., Adenoviral Vector Cytotoxicity Depends in Part on the Transgene Encoded, Biochemical and Biophysical Research Communications, 274, 2000, p767 - 771Journal Article, 2000
  • Liu, X., Wang, W., Singh, B.B., Lockwich, T., Jadlowiec, J., O'Connell, B.C., Wellner, R., Zhu, M.X. and Ambudkar, I.S., Trp1, a Candidate Protein for the Store-Operated Ca(+2) Influx Mechanism in Salivary Gland Cells, J. Biol. Chem., 275, (5), 2000, p3403 - 3411Journal Article, 2000
  • Jung, D.W., Hecht, D., Ho, S.W., O'Connell, B.C., Kleinman, H.K. and Hoffman, M.P., PKC and ERK 1/2 Regulate Amylase Promoter Activity During Differentiation of a Salivary Gland Cell Line, J.Cell Physiol., 185, (2), 2000, p215 - 225Journal Article, 2000
  • Schonherr, E., Schaefer, L., O'Connell, B.C. and Kresse, H., Matrix Metalloproteinase Expression by Endothelial Cells in Collagen Lattices Changes During Co-Culture with Fibroblasts and upon Induction of Decorin Expression, J. Cell Physiol., 187, (1), 2001, p37 - 47Journal Article, 2001
  • Zheng, C., Hoque, A.T.M., Braddon, V.R., Baum, B.J. and O'Connell, B.C., Evaluation of Salivary Gland Acinar and Ductal Cell Specific Promoters In vivo with Recombinant Adenoviral Vectors, Hum. Gene Ther., 12, 2001, p2215 - 2223Journal Article, 2001
  • Fitzgerald, D.H., Coleman, D.C. and O'Connell, B.C., Susceptibility of Candida dubliniensis to Salivary Histatin 3, Antimicrob Agents Chemother, 47, (1), 2003, p70 - 76Journal Article, 2003
  • Fitzgerald, D.H., Coleman, D.C. and O'Connell, B.C., Binding, Internalisation and Degradation of Histatin 3 in histatin resistant derivatives of Candida albicans, FEMS Microbiol Lett., 220, (2), 2003, p247 - 256Journal Article, 2003
  • Zheng, C., O"Connell, B.C., Baum, B.J., Inclusion of Moloney murine leukemia virus elements upstream of the transgene cassette in an E1- deleted adenovirus leads to an unusual genomic integration in epithelial cells, Virology, 313, (2), 2003, p460 - 472Journal Article, 2003
  • O"Connell, B.C., Zheng, C., Jacobson-Kram, D., Baum, B.J., Distribution and toxicity resulting from adenoviral administration to a single salivary gland in adult rats, J. Oral Path Med, 32, (7), 2003, p414 - 421Journal Article, 2003
  • Davis, S. and O'Connell, B.C., The provisional crown, J Irish Dent Assoc, 50, (4), 2004, p167 - 172Journal Article, 2004, TARA - Full Text
  • Yamagishi, H., Fitzgerald, D.H., Sein, T., Walsh, T.J. and O'Connell, B.C., Saliva affects the antifungal activity of exogenously added histatin 3 towards Candida albicans, FEMS Microbiology Lett, 244, (1), 2005, p207 - 212Journal Article, 2005
  • Restoration of non-vital teeth in, editor(s)M. O'Sullivan , Quintessentials of Dental Practice: Fixed Prosthodontics in Dental Practice, London, Quintessence Publishing Co., 2005, pp139 - 158, [O'Connell, B.C.]Book Chapter, 2005
  • Farrell, E., Prendergast, P., O'Brien, F., O'Connell, B.C. and Campbell, V. A, Collagen-Glycosaminoglycans Scaffold Supports Adult Rat Mesenchymal Stem Cell Differentiation Along the Osteogenic and Chondrogenic Routes, Tissue Engineering, 12, (3), 2006, p459 - 468Journal Article, 2006
  • Davis, S.T. and O'Connell, B.C., The Effect of Two Root Canal Sealers on the Retention of Glass Fibre Endodontic Posts, J. Oral Rehab, 34, 2007, p468 - 473Journal Article, 2007, URL , TARA - Full Text
  • Hashem, A.A., Claffey, N.C. and O'Connell, B.C., Pain and Anxiety Following the Placement of Dental Implants, J. Oral. Maxfac. Implants, 21, (6), 2006, p943 - 950Journal Article, 2006
  • Byrne D, Jacobs S, O'Connell B, Houston F, Claffey N, Preloads generated with repeated tightening in three types of screws used in dental implant assemblies, Journal of Prosthodontics, 15, (3), 2006, p164 - 171Journal Article, 2006
  • Farrell, E., Byrne, E.M., Fischer, J., O'Brien, F.J., O'Connell, B.C., Prendergast, P.J. and Campbell, V.A, A comparison of the osteogenic potential of adult rat mesenchymal stem cells cultured in 2-D and on 3-D collagen glycosaminoglycan scaffolds. , Technology and Health Care, 15, 2007, p19 - 31Journal Article, 2007
  • Vag, J., Byrne, E.M., Hughes, D.H., Hoffman, M.H., Ambudkar, I., Maguire, P. and O'Connell, B.C. , Morphological and Functional Differentiation of HSG cells: Role of Extracelleular Matrix and trpc1, J Cell Physiol , 212, (2), 2007, p416 - 423Journal Article, 2007
  • Vanda Szlávik, János Vág, Károly Markó, Kornél Demeter, Emília Madarász, Imre Oláh, Tivadar Zelles, Brian C. O'Connell, Gábor Varga, Matrigel-induced acinar differentiation is followed by apoptosis in HSG cells., J Cell Biochem , 103, 2008, p284 - 295Journal Article, 2008
  • Deirdre H. Fitzgerald-Hughes, David C. Coleman and Brian C. O Connell, Identification of differentially-expressed proteins in derivatives of Candida albicans displaying a stable histatin-3 resistant phenotype, Antimicrobial Agents and Chemotherapy, 51, (8), 2007, p2793 - 2800Journal Article, 2007
  • J.G. McGarry, P. Maguire, V.A. Campbell, B.C. O'Connell, P.J. Prendergast, S.P., Stimulation of Nitric Oxide Mechanotransduction in Single Osteoblasts Using Atomic Force Microscopy, Journal of Orthopedic research, 26, 2008, p513 - 521Journal Article, 2008
  • P Maguire, JI Kilpatrick, G Kelly, PJ Prendergast VA Campbell, BC O'Connell and S Jarvis, Direct Mechanical Measurement of Geodesic Structures in Rat Mesenchymal Stem Cells, HFSP Journal, 1, (3), 2007, p181 - 191Journal Article, 2007
  • B O'Connell and M O'Sullivan, Have Teeth Will Travel:Dental Tourism--Informing the Public, J Ir Dent Assoc, 53, 2007, p180 - 182Journal Article, 2007
  • E. Byrne, E. Farrell, L. A. McMahon, M. G. Haugh, F. J. O'Brien, V. A. Campbell, P. J. Prendergast and B. C. O'Connell, Gene expression by marrow stromal cells in a porous collagen-glycosaminoglycan scaffold is affected by pore size and mechanical stimulation., J Mater Sci: Mater Med, 19, 2008, p3455 - 3463Journal Article, 2008
  • Szlávik V, Szabó B, Vicsek T, Barabás J, Bogdán S, Gresz V, Varga G, O'Connell B,and Vag J, Differentiation of primary human submandibular gland cells cultured on basement, Tissue Eng Part A, 14, (11), 2008, p1915 - 1926Journal Article, 2008
  • Atef A. Hashem, Brian O'Connell, June Nunn, Anne O'Connell, Therese Garvey, Michael O'Sullivan, Tooth agenesis in patients referred to an Irish tertiary care clinic for the developmental dental disorders, Journal of the Irish Dental Association, 56, (1), 2010, p23 - 27Journal Article, 2010, TARA - Full Text
  • Fitzgerald M, O'Sullivan M, O'Connell BC and Houston FJ, Accuracy of Bone Mapping and Guided Flapless Implant Placement in Human Cadavers Using a Model-Based Planning Procedure, International Journal of Oral & Maxillofacial Implants, 25, (5), 2010, p999 - 1006Journal Article, 2010
  • Brennan M, Houston FJ, O'Sullivan M and O'Connell BC, Patient Satisfaction and Oral Health Related Quality of Life Outcomes of Implant Overdentures and Fixed Complete Dentures, International Journal of Oral & Maxillofacial Implants, 25, (4), 2010, p791 - 800Journal Article, 2010
  • Brennan M, Houston FJ, O'Sullivan M and O'Connell BC, Demographics of Implant Placement and Complications of a Patient Sub-Group in a Dental Hospital Population, Journal of the Irish Dental Association, 56, (2), 2010, p85 - 92Journal Article, 2010
  • Kim Jung Ho, McAuliffe P, O'Connell BC, Diamond D and Lau KT, Development of Wireless Bruxism Monitoring Device Based on Pressure Sensitive Polymer, Sensors and Actuators A, 163, (2), 2010, p486-492Journal Article, 2010, DOI , URL , TARA - Full Text
  • Sharkey S, Kelly A, Houston FJ, O'Sullivan M, Quinn F and O'Connell BC, A Radiographic Analysis of Implant Component Misfit, International Journal of Oral & Maxillofacial Implants, 26, (4), 2011, p807 - 815Journal Article, 2011
  • Cellular & Molecular Biomechanics. in, editor(s)T. Clive Lee, Peter F. Niederer , Engineering for Medics and Biologists - An ESEM Primer: Studies in health technology and informatics, Online, IOP Press Online, 2010, pp202-213 , [Campbell VA, O'Connell B]Book Chapter, 2010, URL
  • Campbell VA, O'Connell B, Cellular and molecular biomechanics., Technology and health care , 18, (3), 2010, p233-243Journal Article, 2010, DOI
  • Condon M, Bready M, Quinn F, O'Connell BC, Houston FJ, O'Sullivan M, Maxillary anterior tooth dimensions and proportions in an Irish young adult population., Journal of oral rehabilitation, 2010Journal Article, 2010, DOI
  • Sharkey S, Kelly A, Houston F, O'Sullivan M, Quinn F, O'Connell B, A radiographic analysis of implant component misfit., The International journal of oral & maxillofacial implants, 26, (4), 2011, p807-15Journal Article, 2011
  • Canning T, O'Connell BC, Houston F, O'Sullivan M, The effect of skeletal pattern on determining articulator settings for prosthodontic rehabilitation: an in vivo study., The International journal of prosthodontics, 24, (1), 2011, p16-25Journal Article, 2011
  • Harris D, Höfer S, O'Boyle CA, Sheridan S, Marley J, Benington IC, Clifford T, Houston F, O'Connell B, A comparison of implant-retained mandibular overdentures and conventional dentures on quality of life in edentulous patients: a randomized, prospective, within-subject controlled clinical trial., Clinical oral implants research, 24, (1), 2013, p96 - 103Journal Article, 2013, DOI
  • O'Connell B, Prosthodontics at the crossroads: is this a 'golden age'?, Journal of the Irish Dental Association, 59, (2), 2013, p84-6Journal Article, 2013
  • Hashem A, Kelly A, O'Connell B, O'Sullivan M, Impact of moderate and severe hypodontia and amelogenesis imperfecta on quality of life and self-esteem of adult patients., Journal of dentistry, 41, (8), 2013, p689-94Journal Article, 2013
  • Gallagher S, O'Connell BC ,O'Connell AC, Assessment of occlusion after placement of stainless steel crowns in children--a pilot study, Journal of Oral Rehabilitation, 41, (10), 2014, p730 - 736Journal Article, 2014, DOI
  • O'Sullivan V and O'Connell BC, Water fluoridation, dentition status and bone health of older people in Ireland, Community Dentistry & Oral Epidemiology, 43, (1), 2015, p58 - 67Journal Article, 2015, TARA - Full Text
  • McAuliffe P, Kim JH, Diamond D, Lau KT and O'Connell BC, A sleep bruxism detection system based on sensors in a splint, Journal of oral Rehabilitation, 42, (1), 2015, p34 - 39Journal Article, 2015
  • Brian O'Connell, The Daily Grind-an Update on the Management of Bruxism, The Greater new York Academy of Prosthodontics, New York, USA, 2 December , 2016, GNYAPInvited Talk
  • Brian O'Connell, The Future Starts Now--a Smart Splint, Eastman Institute of Oral Health Centennial, Rochester, New York, 9 June, 2017, EIOHInvited Talk
  • O'Connell, B., Adenovirus-Mediated Gene Transfer to the Salivary Glands, Forsyth Dental Center, Boston, 15/7/93, 1993Invited Talk
  • O'Connell, B., Gene Therapeutics: Supportive Therapies for Cancer Patients, International Society for Oral Oncology, 9th Annual Meeting, Bethesda, 3/6/94, 1994Invited Talk
  • O'Connell, B., Salivary Gland Gene Therapy, University of Alabama, Birmingham, 1/8/94, 1994Invited Talk
  • O'Connell, B., Overview of Gene Therapy (Lecture). Salivary Gland Gene Therapy (Seminar), University of Minnesota, Minneapolis, 6-7/10/94, 1994Invited Talk
  • O'Connell, B., An Integrated Approach to Salivary Gland Repair (Symposium, Plenary lecture). Salivary Gland Gene Therapy (Lunch and Learning), American Association for Dental Research, Annual Session, San Antonio, 10-11/3/95, 1995Invited Talk
  • O'Connell, B., Gene Therapy and Oral Diseases, Academy of Prosthodontics, Annual Meeting, Tucson, 19/5/95, 1995Invited Talk
  • O'Connell, B., DNA as a Therapeutic Agent for Oral Disease, University of Texas Health Science Center, San Antonio, 21/5/96, 1996Invited Talk
  • O'Connell, B., Gene-based Approaches to the Treatment of Oral Disease, Scientific Frontiers in Dentistry Symposium, Bethesda, 14/6/96, 1996Invited Talk
  • O'Connell, B., Therapeutic Interventions: Gene Transfer to Salivary Glands, Salivary Gland Biogenesis and Function, Airlie, Virginia, 10/11/96, 1996Invited Talk
  • O'Connell, B., Salivary Gland Specific Gene Expression-In vivo Gene Transfer as a Tool, Gordon Research Conference: Saliva and Salivary Glands, Ventura, CA, 25/2/97, 1997Invited Talk
  • O'Connell, B., Gene Transfer; How to Teach an Old Gland New Tricks, International Association for Dental Research, Annual Session, Orlando, 21/3/97, 1997Invited Talk
  • O'Connell, B., Prospects for Salivary Gland Gene Therapy, Graduate Student Seminar, University of Rochester, New York, 29/4/97, 1997Invited Talk
  • O'Connell, B., Use of in Vivo Gene Transfer for the Study of Salivary Gland Function, 2nd Stenone Symposium, Cagliari, Italy, 24/5/97, 1997Invited Talk
  • O'Connell, B., Gene Transfer and Gene Therapy, Oral Biology at the Turn of the Century: Misconceptions, Truths, Challenges and Prospects, Interlaken, Switzerland, 20/8/98, 1998, European Research Group for Oral BiologyInvited Talk
  • O'Connell, B., Advances in Gene Therapy, FDI, 86th Annual World Dental Congress; Scientific Frontiers in Clinical Dentistry, Barcelona, Spain, 9/10/98, 1998Invited Talk
  • O'Connell, B., Genetic Regulation and Gene Expression of Salivary Proteins, U.S.-China Workshop on the Role of Saliva in Oral Health, Beijing, 19/10/98, 1998Invited Talk
  • O'Connell, B., Recent Developments in Clinical Research on Saliva, International Association for Dental Research. Annual Session, Vancouver, 12/3/99, 1999Invited Talk
  • O'Connell, B., Gene Therapy for Salivary Gland Dysfunction, 5th European Symposium on the Application of Saliva in Clinical Practice and Research, Egmond aan Zee, Netherlands, 20/5/99, 1999Invited Talk
  • O'Connell, B., Gene Transfer Technology and the Oral Cavity, Latin American Association for Salivary Research, 3rd International Meeting, Vina del Mar, Chile, 15/11/99, 1999Invited Talk
  • O'Connell, B., Viral-mediated Gene Transfer to the Salivary Glands, University of Manchester, Biological Sciences-Physiology section, 15/12/99, 1999Invited Talk
  • O'Connell, B., Fear of Failure in Prosthodontics, Midland Western Postgraduate Dental Foundation. Annual Meeting, Dromoland Co. Clare, 11-12/2/00, 2000Invited Talk
  • O'Connell, B., Salivary gland development, regeneration and repair-summary and future directions, 16th International Conference on Oral Biology, Chantilly, Virginia, 12/4/00, 2000Invited Talk
  • O'Connell, B., Treatment Planning in Prosthodontics, Munster Branch, IDA. Annual Scientific Session, Cork, 22/9/00, 2000Invited Talk
  • O'Connell, B., Saliva in Health and Disease-Repair and regeneration, Swedish Dental Association, Annual Congress, Stockholm, 27/10/00, 2000Invited Talk
  • O'Connell, B., Functional Genomics, Gordon Research Conference: Saliva and Salivary Glands, Ventura, CA, 16/2/01, 2001Invited Talk
  • O'Connell, B., Genes and the Prosthodontist, American College of Prosthodontists, Annual Session, New Orleans, 2/11/01, 2001Invited Talk
  • O'Connell, B., Restoration of Endodontically Treated Teeth, South Eastern Branch, IDA, Scientific Conference, Waterford, 22/2/2002, 2002Invited Talk
  • O'Connell, B., Restorative Dentistry in the Molecular Age, American Dental Society of Europe, Annual Conference, Prague, June, 2002Invited Talk
  • O'Connell, B., Orthodontic, Periodontic, Prosthodontic-the Interrelationship, European Begg Society of Orthodontics, Annual Conference, Dublin, May, 2003Invited Talk
  • O'Connell, B., Bioengineering and Restorative Dentistry, International College of Dentists, Annual Conference, Dublin, June, 2003Invited Talk
  • O'Connell, B., Restorative Dentistry in the Molecular Age, University of Rochester, Annual Alumni Conference, Florida, November, 2003Invited Talk
  • O'Connell, B., Restoration of Endodontically-Treated Teeth-the Evidence, Destination Ireland, University of Minnesota, October, 2004Invited Talk
  • O'Connell, B., Developmental defects of the dentition-diagnosis to management, South-Eastern Branch, PGMDB., Kilkenny, December, 2004Invited Talk

Research Expertise

  • Title
    Production and Testing of Adenovirus Vectors for Clinical Use
    Summary
    Funding Agency
    NIH-NIDCR Research and Development Contract.
    Date From
    6/97
    Date To
    5/99
  • Title
    SMART SPLINT
    Summary
    Superior monitoring & analysis relayed through sensors providing longitudinal information on nocturnal tooth grinding
    Funding Agency
    Enterprise Ireland
    Date From
    October 2008
    Date To
    October 2009
  • Title
    Mechanobiology of Tissue Engineering
    Summary
    Theme Co-ordinator. Trinity Centre for Bioengineering (TCBE)
    Funding Agency
    Higher Education Authority-PRTLI
    Date From
    2002
    Date To
    2007
  • Title
    Regulation of Salivary Gland Gene Expression
    Summary
    Funding Agency
    Wellcome Trust-Travelling Fellowship
    Date From
    2003
    Date To
    2005
  • Title
    Antifungal Mechanism of Human Salivary Histatin
    Summary
    Funding Agency
    Health Research Board-Project Grant
    Date From
    2002
  • Title
    In vivo function and regulation of salivary antimicrobial proteins
    Summary
    Funding Agency
    Health Research Board-Project Grant.
    Date From
    2000
    Date To
    2003
  • Title
    Provost Award
    Summary
    Funding Agency
    Trinity College Dublin
    Date From
    1999
    Date To
    1999
  • Title
    Differential cellular response to nanoscale engineered titanium surfaces
    Summary
    Co-Principal Investigator
    Date From
    2005
    Date To
    2009
  • Title
    Cells Under Strain
    Summary
    Project leader, Centre for Research on Adaptive Nanostructures and Nanodevices (CRANN)
    Funding Agency
    Science Foundation Ireland (SFI)
    Date From
    2004
  • Title
    Real Time PCR equipment
    Summary
    Funding Agency
    Health Research Board-Co-investigator for equipment grant.
    Date From
    2000
    Date To
    2000
  • Title
    Investigative and Therapeutic Gene Transfer to the Salivary Glands
    Summary
    Funding Agency
    NIH Grant-NIDCR Project Z01-DE00675-01-03
    Date From
    1996
    Date To
    1999
  • Title
    Construction of Adenovirus Vectors for the Study of Gene Control and Protein Function
    Summary
    Funding Agency
    NIH-NIDCR Research and Development Contract.
    Date From
    6/97
    Date To
    5/00

Recognition

  • College Scholar (U.C.C.) 1980
  • Edward Gurr Prize (U.C.C.) 1981
  • Fellow, American College of Prosthodontists 1999
  • Gold Medal Restorative Dentistry (U.C.C.) 1984
  • Peel Memorial Award (U.C.C.) 1984
  • AADR/IADR Hatton Award, First Place, (International Young Investigator) 1992
  • U.C.C. Scholarship 1982
  • NIDR Travel Award 1995
  • Fellow, Trinity College, Dublin 2002
  • Bloor Award (U. Rochester) (First Place Biochemistry Doctorate) 1993
  • American Association for the Advancement of Science
  • Fellow of the American College of Prosthodontists
  • International Association for Dental Research
  • American Society for Biochemistry and Molecular Biology
  • Critical Reviews in Oral Biology and Medicine (Reviewer)
  • Journal of Dental Research (Editorial Board)
  • Oral Diseases (Editorial Board)
  • Antimicrobial Agents and Chemotherapy (Reviewer)
  • Anatomical Record (Reviewer)
  • Archives of Oral Biology (Reviewer)
  • American Heart Association (Grant reviewer)
  • International Journal of Cancer (Reviewer)
  • Oral Bioscience and Medicine (Editorial Board)