Professor Stephen Connon

• Tallon, S. Manoni, F. Connon, S.J., A practical aryl unit for azlactone dynamic kinetic resolution: Orthogonally protected products and a ligation-inspired coupling process, Angewandte Chemie International Edition, 54, (3), 2015, p813 - 817Journal Article, 2015, DOI , URL
• Myles, L. Gathergood, N. Connon, S.J., An organocatalytic process for the hydrolytic cleavage of dithianes mediated by imidazolium ions: No harsh agents required, European Journal of Organic Chemistry, 2015, (1), 2015, p188 - 194Journal Article, 2015, DOI , URL
• Cronin SA, Gutiérrez Collar A, Gundala S, Cornaggia C, Torrente E, Manoni F, Botte A, Twamley B, Connon SJ, The first catalytic asymmetric cycloadditions of imines with an enolisable anhydride., Organic & biomolecular chemistry, 14, (29), 2016, p6955-9Journal Article, 2016, DOI
• Cornaggia, C., Gundala, S., Manoni, F., Gopalasetty, N., Connon, S.J., Catalytic formal cycloadditions between anhydrides and ketones: Excellent enantio and diastereocontrol, controllable decarboxylation and the formation of adjacent quaternary stereocentres, Organic and Biomolecular Chemistry, 14, (11), 2016, p3040-3046Journal Article, 2016, DOI
• Sorrentino, E., Connon, S.J., Enantioselective Alkylative Kinetic Resolution of 2-Oxindole-Derived Enolates Promoted by Bifunctional Phase Transfer Catalysts, Organic Letters, 18, (20), 2016, p5204-5207Journal Article, 2016, DOI
• Varghese S, Cotter M, Chevot F, Fergus C, Cunningham C, Mills KH, Connon SJ, Southern JM, Kelly VP., In vivo modification of tRNA with an artificial nucleobase leads to full disease remission in an animal model of multiple sclerosis., Nucleic Acids Research, 45, (4), 2017, p2029-2039Journal Article, 2017, DOI
• Roucan, M. and Kielmann, M. and Connon, S.J. and Bernhard, S.S.R. and Senge, M.O., Conformational control of nonplanar free base porphyrins: Towards bifunctional catalysts of tunable basicity, Chemical Communications, 54, (1), 2018, p26-29Journal Article, 2018, DOI , URL , TARA - Full Text
• Trujillo, C. and Rozas, I. and Botte, A. and Connon, S.J., A DFT mechanistic study of the organocatalytic asymmetric reaction of aldehydes and homophthalic anhydride, Chemical Communications, 53, (63), 2017, p8874-8877Journal Article, 2017, DOI , URL , TARA - Full Text
• Kumar, V. and Connon, S.J., Direct, efficient NHC-catalysed aldehyde oxidative amidation:: In situ formed benzils as unconventional acylating agents, Chemical Communications, 53, (73), 2017, p10212-10215Journal Article, 2017, DOI , URL
• Manoni, F. and Farid, U. and Trujillo, C. and Connon, S.J., Catalytic asymmetric Tamura cycloadditions involving nitroalkenes, Organic and Biomolecular Chemistry, 15, (6), 2017, p1463-1474Journal Article, 2017, DOI , URL
• Craig, R. and Sorrentino, E. and Connon, S.J., Enantioselective Alkylation of 2-Oxindoles Catalyzed by a Bifunctional Phase-Transfer Catalyst: Synthesis of (â^')-Debromoflustramine B, Chemistry - A European Journal, 24, (18), 2018, p4528-4531Journal Article, 2018, DOI , URL , TARA - Full Text
• Delany, E.G. and Connon, S.J., Highly chemoselective intermolecular cross-benzoin reactions using an: Ad hoc designed novel N-heterocyclic carbene catalyst, Organic and Biomolecular Chemistry, 16, (5), 2018, p780-786Journal Article, 2018, DOI , URL
• Claveau, R. and Twamley, B. and Connon, S.J., Dynamic kinetic resolution of bis-aryl succinic anhydrides: Enantioselective synthesis of densely functionalised γ-butyrolactones, Chemical Communications, 54, (26), 2018, p3231-3234Journal Article, 2018, DOI , URL
• Collar A.G, Trujillo C, Connon S.J, Highly Enantio- and Diastereoselective Catalytic Asymmetric Tamura Cycloaddition Reactions, Chemistry - A European Journal, 2019Journal Article, 2019, DOI , URL
• Collar A.G, Trujillo C, Lockett-Walters B, Twamley B, Connon S.J, Catalytic Asymmetric γ-Lactam Synthesis from Enolisable Anhydrides and Imines, Chemistry - A European Journal, 2019Journal Article, 2019, DOI , URL
• Aiello M.L, Farid U, Trujillo C, Twamley B, Connon S.J, Catalytic Asymmetric Cycloadditions between Aldehydes and Enolizable Anhydrides: Cis-Selective Dihydroisocoumarin Formation, Journal of Organic Chemistry, 83, (24), 2018, p15499 - 15511Journal Article, 2018, DOI , URL
• Claveau R, Twamley B, Connon S.J, Synthesis of α-alkylated γ-butyrolactones with concomitant anhydride kinetic resolution using a sulfamide-based catalyst, Organic and Biomolecular Chemistry, 16, (41), 2018, p7574 - 7578Journal Article, 2018, DOI , URL
• Craig R, Litvajova M, Cronin S.A, Connon S.J, Enantioselective acyl-transfer catalysis by fluoride ions, Chemical Communications, 54, (72), 2018, p10108 - 10111Journal Article, 2018, DOI , URL
• Mashael A. Alqasem, Claire Fergus, J. Mike Southern, Stephen J. Connon and Vincent P. Kelly, The eukaryotic tRNA-guanine transglycosylase enzyme inserts queuine into tRNA via a sequential bi-bi mechanism, Chemical communications, 56, 2020, p3915 - 3918Journal Article, 2020, DOI , URL , TARA - Full Text
• Gleeson, O., Tekoriute, R., Gun'ko, Y.K., Connon, S.J., The first magnetic nanoparticle-supported chiral dmap analogue: Highly enantioselective acylation and excellent recyclability, Chemistry - A European Journal, 15, (23), 2009, p5669-5673Journal Article, 2009
• C. Ó Dálaigh, S. J. Hynes, D. J. Maher and S. J. Connon, Kinetic resolution of sec-alcohols using a new class of readily assembled (S)-proline-derived 4-(pyrrolidino)-pyridine analogues, Organic and Biomolecular Chemistry, 3, (6), 2005, p981 - 984Journal Article, 2005, DOI , URL , TARA - Full Text
• J. E. Murtagh, S. H. McCooey and S. J. Connon, Novel amine-catalysed hydroalkoxylation reactions of alkenes and alkynes, Chemical Communications, (2), 2005, p227 - 229Journal Article, 2005, DOI , URL , TARA - Full Text
• C. Faltin, E. M. Fleming and S. J. Connon, Acrylamide in the Baylis-Hillman reaction, Journal of Organic Chemistry, 69, (19), 2004, p6496 - 6499Journal Article, 2004, DOI , URL
• D. J. Maher and S. J. Connon, Acceleration of the DABCO-promoted Baylis-Hillman reaction using a recoverable H-bonding organocatalyst, Tetrahedron Letters, 35, (19), 2004, p1301 - 1305Journal Article, 2004, DOI , URL
• S. J. Connon and A. F. Hegarty, Stabilised 2,3-pyridyne reactive intermediates of exceptional dienophilicity, European Journal of Organic Chemistry, 16, 2004, p3477 - 3483Journal Article, 2004, DOI , URL
• S. J. Connon and S. Blechert, Recent advances in alkene metathesis, Topics in Organometallic Chemistry, 11, 2004, p93 - 124Journal Article, 2004, DOI , URL
• M. Zaja, S. J. Connon, A. M. Dunne, M. Rivard, N. Buschmann, J. Jiricek and S. Blechert, Ruthenium olefin metathesis catalysts with modified styrene ethers: influence of steric and electronic effects, Tetrahedron, 59, (34), 2003, p6545 - 6558Journal Article, 2003, DOI , URL
• S. J. Connon and S. Blechert, Recent developments in olefin cross metathesis, Angewandte Chemie, International Edition, 42, (17), 2003, p1900 - 1923Journal Article, 2003, DOI , URL
• S. J. Connon, M. Rivard, M. Zaja and S. Blechert, Practical olefin metathesis in protic media under an air atmosphere, Advanced Synthesis and Catalysis, 34, (34), 2003, p572 - 575Journal Article, 2003, DOI , URL
• N. Lucas, S. Randl, S. J. Connon and S. Blechert, A mechanism switch in enyne metathesis reactions involving rearrangement: influence of heteroatoms in the propargylic position, Advanced Synthesis and Catalysis, (344), 2002, p631 - 633Journal Article, 2002, DOI , URL
• S. J. Connon and S. Blechert, Olefin metathesis catalysts based on ring-opening-prepared polymer-supported transition metal complexes, 2004, EP 1394190Patent, 2004
• S. J. Connon, A. M. Dunne and S. Blechert, A self-generating and recyclable polymer-bound olefin metathesis catalyst, Angewandte Chemie, International Edition, 41, (20), 2002, p3835 - 3838Journal Article, 2002, DOI , URL
• S. J. Connon and S. Blechert, A polymer-supported phosphine-free ruthenium alkylidene for olefin metathesis in methanol and water, Bioorganic and Medicinal Chemistry Letters, 12, (14), 2002, p1873 - 1876Journal Article, 2002, DOI , URL
• S. Randl, S. J. Connon and S. Blechert, Ring-opening cross metathesis of unstrained cycloalkenes, Chemical Communications, 18, 2001, p1796 - 1797Journal Article, 2001, DOI , URL
• S. Randl, N. Buschmann, S. J. Connon and S. Blechert, Highly efficient and recyclable polymer-bound catalyst for olefin metathesis reactions, Synlett, 10, 2001, p1547 - 1550Journal Article, 2001, DOI , URL
• S. J. Connon and A. F. Hegarty, Diels-Alder cycloadditions of stabilised 2,3-pyridynes, Tetrahedron Letters, 42, (4), 2001, p735 - 737Journal Article, 2001, DOI , URL
• S. J. Connon and A. F. Hegarty, Substituted 3,4-pyridynes: clean cycloadditions, Journal of the Chemical Society, Perkin Transactions 1, 1, (8), 2000, p1245 - 1249Journal Article, 2000, DOI , URL , TARA - Full Text
• McDonnell, C.M. and Ghanim, M. and Mike Southern, J. and Kelly, V.P. and Connon, S.J., De-novo designed β-lysine derivatives can both augment and diminish the proliferation rates of E. coli through the action of Elongation Factor P, Bioorganic and Medicinal Chemistry Letters, 59, (128545), 2022Journal Article, 2022, DOI , TARA - Full Text
• Connon, S.J., Blechert, S., A solid-supported phosphine-free ruthenium alkylidene for olefin metathesis in methanol and water, Bioorganic and Medicinal Chemistry Letters, 12, (14), 2002, p1873-1876Journal Article, 2002, DOI
• Connon, S.J., Dunne, A.M., Blechert, S., A self-generating, highly active, and recyclable olefin-metathesis catalyst, Angewandte Chemie - International Edition, 41, (20), 2002, p3835-3838Journal Article, 2002, DOI
• Cornaggia, C., Manoni, F., Torrente, E., Tallon, S., Connon, S.J., A catalytic asymmetric reaction involving enolizable anhydrides, Organic Letters, 14, (7), 2012, p1850-1853Journal Article, 2012, DOI
• Palacio, C., Connon, S.J., C-5"-substituted cinchona alkaloid derivatives catalyse the first highly enantioselective dynamic kinetic resolutions of azlactones by thiolysis, European Journal of Organic Chemistry, (24), 2013, p5398-5413Journal Article, 2013, DOI
• Lockett-Walters, B., Trujillo, C., Twamley, B., Connon, S., The base-catalysed Tamura cycloaddition reaction: Calculation, mechanism, isolation of intermediates and asymmetric catalysis, Chemical Communications, 55, (75), 2019, p11283-11286Journal Article, 2019, DOI
• Trujillo, C., Litvajova, M., Cronin, S.A., Craig, R., Connon, S.J., The Steglich Rearrangement of 2-Oxindole Derivatives Promoted by Anion-based Nucleophilic Catalysis, ChemCatChem, 2019Journal Article, 2019, DOI
• Maguire, A.C., Kumar, V., Connon, S.J., Highly chemoselective, sterically sensitive NHC-catalysed amine acylation with pyridil, Chemical Communications, 55, (90), 2019, p13526-13529Journal Article, 2019, DOI
• Farid, U., Aiello, M.L., Connon, S.J., Highly Enantioselective Catalytic Kinetic Resolution of "-Branched Aldehydes through Formal Cycloaddition with Homophthalic Anhydrides, Chemistry - A European Journal, 25, (43), 2019, p10074-10079Journal Article, 2019, DOI
• Smith, S.N., Craig, R., Connon, S.J., Divergent Synthesis of "-Amino Acid and "-Lactam Derivatives from meso-Glutaric Anhydrides, Chemistry - A European Journal, 26, (59), 2020, p13378-13382Journal Article, 2020, DOI
• Curran, S.P., Fallon, B.J., Connon, S.J., C₂-Symmetric Cinchona Alkaloid Derivatives: Versatile Catalysts for the Enantioselective C"C Bond Forming Conjugate Addition of Nucleophiles to Simple ",ß-Unsaturated Acyl Pyrazoles, ChemistrySelect, 5, (48), 2020, p15190-15194Journal Article, 2020, DOI
• Cronin, S.A., Connon, S.J., The kinetic resolution of oxazinones by alcoholysis: access to orthogonally protected ß-amino acids, Organic and Biomolecular Chemistry, 19, (34), 2021, p7348-7352Journal Article, 2021, DOI
• Smith, S.N., Connon, S.J., Preparation of Lactams from Cyclic Anhydrides via N-Carboxyanhydride Intermediates, European Journal of Organic Chemistry, 2021, (40), 2021, p5540-5544Journal Article, 2021, DOI
• Delany, E.G., Connon, S.J., Enantioselective N-heterocyclic carbene-catalysed intermolecular crossed benzoin condensations: Improved catalyst design and the role of in situ racemisation, Organic and Biomolecular Chemistry, 19, (1), 2021, p248-258Journal Article, 2021, DOI
• Litvajova, M., Sorrentino, E., Twamley, B., Connon, S.J., Base-free enantioselective S_N2 alkylation of 2-oxindoles via bifunctional phase-transfer catalysis, Beilstein Journal of Organic Chemistry, 17, 2021, p2287-2294Journal Article, 2021, DOI
• Trujillo, C., Cronin, S.A., Connon, S.J., Mechanistic Insights into the Organocatalytic Kinetic Resolution of Oxazinones through Alcoholysis, European Journal of Organic Chemistry, 2022, (3), 2022Journal Article, 2022, DOI
• Curran, S.P., Connon, S.J., The thiolate-catalyzed intermolecular crossed tishchenko reaction: Highly chemoselective coupling of two different aromatic aldehydes, Angewandte Chemie - International Edition, 51, (43), 2012, p10866-10870Journal Article, 2012, DOI
• Rodríguez-Docampo, Z., Quigley, C., Tallon, S., Connon, S.J., The dynamic kinetic resolution of azlactones with thiol nucleophiles catalyzed by arylated, deoxygenated cinchona alkaloids, Journal of Organic Chemistry, 77, (5), 2012, p2407-2414Journal Article, 2012, DOI
• Faltin, C., Fleming, E.M., Connon, S.J., Acrylamide in the Baylis-Hillman reaction: Expanded reaction scope and the unexpected superiority of DABCO over more basic tertiary amine catalysts, Journal of Organic Chemistry, 69, (19), 2004, p6496-6499Journal Article, 2004, DOI
• Smith S.N., Trujillo C., Connon S.J., Catalytic, asymmetric azidations at carbonyls: achiral and meso-anhydride desymmetrisation affords enantioenriched "-lactams, Organic and Biomolecular Chemistry, 20, (32), 2022, p6384 - 6393, p6384-6393Journal Article, 2022, DOI , TARA - Full Text
• S. H. McCooey and S. J. Connon, Urea- and Thiourea-Substituted Cinchona Alkaloid Derivatives as Highly Efficient Bifunctional Organocatalysts for the Asymmetric Addition of Malonate to Nitroalkenes: Inversion of Configuration at C9 Dramatically Improves Catalyst Performance, Angewandte Chemie, International Edition, 44, (39), 2005, p6367 - 6370Journal Article, 2005, DOI , URL
• Oì Daìlaigh, C., Corr, S.A., Gun'ko, Y., Connon, S.J., A magnetic-nanoparticle-supported 4-N,N-dialkylaminopyridine catalyst: Excellent reactivity combined with facile catalyst recovery and recyclability , Angewandte Chemie - International Edition , 46, (23), 2007, p4329-4332Journal Article, 2007, DOI
• Connon, S.J. , Asymmetric organocatalytic reductions mediated by dihydropyridines , Organic and Biomolecular Chemistry , 5, (21), 2007, p3407-3417Journal Article, 2007, DOI , URL , TARA - Full Text
• Connon, S.J. , Organocatalysis mediated by (thio)urea derivatives , Chemistry - A European Journal, 12, (21), 2006, p5418-5427Journal Article, 2006, DOI , URL
• Connon, S.J. , Chiral phosphoric acids: Powerful organocatalysts for asymmetric addition reactions to imines , Angewandte Chemie - International Edition , 45, (24), 2006, p3909-3912Journal Article, 2006, DOI , URL
• Connon, S.J., Catalytic asymmetric acyl-transfer mediated by chiral pyridine derivatives, ChemInform, 37, (42), 2006, p333-338Journal Article, 2006, DOI , URL
• Connon, S.J., Review of Catalytic Asymmetric Acyl-transfer Mediated by Chiral Pyridine Derivatives, by Connon, S.J. , Letters in Organic Chemistry , 3, (5), 2006, p333-338Review, 2006, URL
• Connon, S.J., Blechert, S. , solid-supported phosphine-free ruthenium alkylidene for olefin metathesis in methanol and water , Bioorganic and Medicinal Chemistry Letters , 12, (14), 2002, p1873-1876Journal Article, 2002, DOI , URL
• Fleming, E.M., Quigley, C., Rozas, I., Connon, S.J. , Computational study-led organocatalyst design: A novel, highly active urea-based catalyst for addition reactions to epoxides , Journal of Organic Chemistry, 73, (3), 2008, p948-956Journal Article, 2008, DOI , URL
• Ciarán Ó Dálaigh and Stephen J. Connon, Nonenzymatic acylative kinetic resolution of Baylis-Hillman adducts, Journal of Organic Chemistry , 72, (18), 2007, p7066-7069Journal Article, 2007, DOI , URL
• Procuranti, B., Connon, S.J. , A reductase-mimicking thiourea organocatalyst incorporating a covalently bound NADH analogue: Efficient 1,2-diketone reduction with in situ prosthetic group generation and recycling , Chemical Communications , 14, 2007, p1421-1423Journal Article, 2007, DOI , URL , TARA - Full Text
• McCooey, S.H., Connon, S.J. , Readily accessible 9-epi-amino cinchona alkaloid derivatives promote efficient, highly enantioselective additions of aldehydes and ketones to nitroolefins , Organic Letters , 9, (4), 2007, p599-602Journal Article, 2007, DOI , URL
• Fleming, E.M., McCabe, T., Connon, S.J. , Novel axially chiral bis-arylthiourea-based organocatalysts for asymmetric Friedel-Crafts type reactions , Tetrahedron Letters , 47, (39), 2006, p7037-7042Journal Article, 2006, DOI , URL
• McCooey, S.H. , McCabe, T. , Connon, S.J. , Stereoselective synthesis of highly functionalized nitrocyclopropanes via organocatalyic conjugate addition to nitroalkenes, Journal of Organic Chemistry , 71, (19), 2006, p7494-7497Journal Article, 2006, DOI , URL
• Ciarán Ó. Dálaigh, Stephen J. Hynes, John E. O'Brien, Thomas McCabe, Declan J. Maher, Graeme W. Watson and Stephen J. Connon, Asymmetric acyl-transfer promoted by readily assembled chiral 4-N,N-dialkylaminopyridine derivatives , Organic and Biomolecular Chemistry , 4, (14), 2006, p2785-2793Journal Article, 2006, DOI , URL , TARA - Full Text
• Randl, S., Lucas, N., Connon, S.J., Blechert, S. , Erratum: (Advance Synthesis and Catalysis (2002) 6-7 (631-633)) , Advanced Synthesis and Catalysis , 345, (6-7), 2003, pA75Journal Article, 2003
• O. Gleeson, R. Tekoriute, Y. K. Gun'ko, S. J. Connon, The First Magnetic Nanoparticle-Supported Chiral DMAP Analogue: Highly Enantioselective Acylation and Excellent Recyclability, Chemistry: A European Journal, 15, (23), 2009, p5669-5673Journal Article, 2009, DOI
• David P. Power, Olivier Lozach, Laurent Meijer, David H. Grayson, Stephen J. Connon, Concise synthesis and CDK/GSK inhibitory activity of the missing 9-azapaullones, Bioorganic & Medicinal Chemistry Letters, 20, (16), 2010, 4940-4944Journal Article, 2010, DOI , URL , TARA - Full Text
• C. Palacio and S. J. Connon, A new class of urea-substituted cinchona alkaloid promote highly enantioselective nitroaldol reactions of trifluoromethylketones., Organic Letters, 13, (6), 2011, p1298-1301Journal Article, 2011, DOI
• S. Tallon, A. C. Lawlor and S. J. Connon, Urea-catalyzed transthioesterification: towards a new kinetic resolution methodology, Arkivoc , 4, 2011, p115-126Journal Article, 2011, URL
• C. A. Rose, S. Gundala, K. Zeitler and S. J. Connon, Chemoselective crossed acyloin condensations: catalyst and substrate control, Synthesis , 2011, (2), 2011, p190-198Journal Article, 2011, DOI , URL , TARA - Full Text
• C. J. O' Connor, F. Manoni, S. P. Curran and S. J. Connon, Microwave-assisted efficient thiolate-catalysed homo- and crossed intermolecular Tishchenko reactions, New Journal of Chemistry, 35, 2011, p1-3Journal Article, 2011, DOI , URL , TARA - Full Text
• S. E. O'Toole, C. A. Rose, S. Gundala, K. Zeitler and S. J. Connon, Highly chemoselective direct crossed aliphatic- aromatic acyloin condensations with triazolium-derived carbene catalysts, Journal of Organic Chemistry, 76, (2), 2011, p347-357Journal Article, 2011, DOI , URL , TARA - Full Text
• S. A. Kavanagh, A. Piccinini and S. J. Connon*, Efficient catalytic Corey-Chaykovsky reactions involving ketone substrates., Advanced Synthesis & Catalysis, 352, (11-12), 2010, p2089-2093Journal Article, 2010, DOI
• L. Myles, R. Gore, N. Gathergood and S. J. Connon, Highly recyclable, imidazolium derived ionic liquids of low antimicrobial and antifungal toxicity: A new strategy for acid catalysis, Green Chemistry, 12, 2010, p1157-1162Journal Article, 2010, DOI , URL , TARA - Full Text
• L. Cronin, F.Manoni, C. J. O' Connor and S.J. Connon*, Tunable bromomagnesium thiolate Tishchenko reaction catalysts: efficient intermolecular aldehyde-trifluoromethylketone coupling, Angewandte Chemie International Edition, 49, (17), 2010, p3045-3048Journal Article, 2010, DOI , URL , TARA - Full Text
• A. Peschiulli, B. Procuranti, C. J. O' Connor and S. J. Connon, Synergistic organocatalysis in the kinetic resolution of secondary thiols with concomitant desymmetrisation of an anhydride., Nature Chemistry , 2, 2010, p380-384Journal Article, 2010, DOI , URL , TARA - Full Text
• Piccinini, S. A. Kavanagh, P. B. Connon and S. J. Connon, Catalytic (asymmetric) methylene transfer to aldehydes, Organic Letters, 12, (3), 2010, p608-611Journal Article, 2010, DOI , URL , TARA - Full Text
• B. Procuranti, L. Myles, N. Gathergood and S. J.Connon* , Pyridinium ion catalysis of carbonyl protection reactions, Synthesis, 23, 2009, p4082-4086Journal Article, 2009, DOI
• L. Baragwanath, C. A. Rose, K. Zeitler and S. J. Connon*, Highly enantioselective benzoin condensation reactions involving a bifunctional protic pentafluorophenyl-substituted triazolium precatalyst, Journal of Organic Chemistry, 74, (23), 2009, p9214-9217Journal Article, 2009, DOI
• S. E. O'Toole and S. J. Connon, The enantioselective benzoin condensation promoted by chiral triazolium precatalysts: stereochemical control via hydrogen bonding., Organic Biomolecular Chemistry, 7, (17), 2009, p3584-3593Journal Article, 2009, DOI , URL , TARA - Full Text
• S. J. Connon*, The design of novel, synthetically useful (thio)urea-based organocatalysts, Synlett, 3, 2009, p354-376Journal Article, 2009, DOI
• B. Procuranti and S. J. Connon*, Unexpected catalysis: aprotic pyridinium ions as active and recyclable Brønsted acid catalysts in protic media', Organic Letters, 10, (21), 2008, p4935-4938Journal Article, 2008, DOI
• A. Peschiulli, C. Quigley, S. Tallon, Y. K. Gun'ko* and S. J. Connon*, Organocatalytic asymmetric addition of alcohols and thiols to activated electrophiles - efficient dynamic kinetic resolution and desymmetrization protocols, Journal of Organic Chemistry, 73, (16), 2008, p6409-6412Journal Article, 2008, DOI
• A. Peschiulli, Y. Gun'ko* and S. J. Connon*, Highly enantioselective desymmetrization of meso anhydrides by a bifunctional thiourea-based organocatalyst at low catalyst loadings and room temperature, Journal of Organic Chemistry, 73, (6), 2008, p2454-2457Journal Article, 2008, DOI
• S. A. Kavanagh and S. J. Connon, N-Alkyl salts derived from ephedrine do not promote enantioselective Corey-Chaykovsky reactions involving sulfonium methylides under phase transfer conditions, Tetrahedron: Asymmetry , 19, (12), 2008, p1414-1417Journal Article, 2008, DOI
• S. J. Connon, Asymmetric catalysis with bifunctional cinchona alkaloid-based urea and thiourea organocatalysts, Chemical Communcations, 2008, p2499-2510Journal Article, 2008, DOI , URL , TARA - Full Text
• S. J. Connon*, The catalytic asymmetric Strecker reaction - ketimines continue to join the fold, Angewandte Chemie International Edition, 47, (7), 2008, p1176-1178Journal Article, 2008, DOI
• S. A. Kavanagh, A. Piccinini, E. M. Fleming and S. J. Connon , Urea derivatives are highly active catalysts for the base-mediated generation of terminal epoxides from aldehydes and trimethylsulfonium iodide, Organic Biomolecular Chemistry, 6, (8), 2008, p1339-1343Journal Article, 2008, DOI , URL , TARA - Full Text
• Noonan, C., Baragwanath, L., Connon, S.J., Nucleophilic carbene-catalysed oxidative esterification reactions , Tetrahedron Letters, 49, (25), 2008, p4003-4006Journal Article, 2008, DOI
• S. J. Connon, S. Blechert, and BASF AG, Novel metathesis catalysts, 2003, 03016465.1Patent, 2003
• A. Peschiulli, L. Markey and S. J. Connon, Intermediates in the Enantioselective Synthesis of 3-(Aminomethyl)-5-Methyl-Hexanoic Acid, 2009, EP09151679.9Patent, 2009
• A. Peschiulli, B. Procuranti and S. J. Connon, Kinetic Resolution, 2009, EP09178565.9.Patent, 2009
• C. A. Rose, S. Gundala, C. L. Fagan, J. F. Franz, S. J. Connon* and K. Zeitler*, NHC-Catalysed, chemoselective crossed-acyloin reactions, Chemical Science, 2012, p735-Journal Article, 2012, DOI , URL , TARA - Full Text
• Gleeson O, Davies GL, Peschiulli A, Tekoriute R, Gun'ko YK, Connon SJ, The immobilisation of chiral organocatalysts on magnetic nanoparticles: the support particle cannot always be considered inert., Organic & biomolecular chemistry, 9, (22), 2011, p7929-40Journal Article, 2011, DOI , TARA - Full Text
• Manoni, F, Connon, SJ, Catalytic Asymmetric Tamura Cycloadditions, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 53, (10), 2014, p2628-2632Journal Article, 2014, DOI
• Myles, L, Gore, RG, Gathergood, N, Connon, SJ, A new generation of aprotic yet Bronsted acidic imidazolium salts: low toxicity, high recyclability and greatly improved activity, GREEN CHEMISTRY, 15, (10), 2013, p2740-2746Journal Article, 2013, DOI , TARA - Full Text
• Gore, RG, Truong, TKT, Pour, M, Myles, L, Connon, SJ, Gathergood, N, Tandem ionic liquid antimicrobial toxicity and asymmetric catalysis study: carbonyl-ene reactions with trifluoropyruvate, GREEN CHEMISTRY, 15, (10), 2013, p2727-2739Journal Article, 2013, DOI , TARA - Full Text
• Connon, S.J., Diaminocyclopropenylidene organocatalysts: Beyond N-heterocyclic carbenes , Angewandte Chemie - International Edition , 53, (5), 2014, p1203-1205Journal Article, 2014, DOI
• Gore, RG, Myles, L, Spulak, M, Beadham, I, Garcia, MT, Connon, SJ, Gathergood, N, A new generation of aprotic yet Bronsted acidic imidazolium salts: effect of ester/amide groups in the C-2, C-4 and C-5 on antimicrobial toxicity and biodegradation, GREEN CHEMISTRY, 15, (10), 2013, p2747-2760Journal Article, 2013, DOI , TARA - Full Text
• Palacio, C, Connon, SJ, C-5-Substituted Cinchona Alkaloid Derivatives Catalyse the First Highly Enantioselective Dynamic Kinetic Resolutions of Azlactones by Thiolysis, EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2013, (24), 2013, p5398-5413Journal Article, 2013, DOI
• Delany, E.G., Fagan, C.-L., Gundala, S., Zeitler, K., Connon, S.J., Aerobic oxidation of NHC-catalysed aldehyde esterifications with alcohols: Benzoin, not the Breslow intermediate, undergoes oxidation, Chemical Communications , 49, (58), 2013, p6513-6515Journal Article, 2013, DOI , TARA - Full Text
• Delany, EG, Fagan, CL, Gundala, S, Mari, A, Broja, T, Zeitler, K, Connon, SJ, NHC-catalysed aerobic aldehyde-esterifications with alcohols: no additives or cocatalysts required, CHEMICAL COMMUNICATIONS, 49, (58), 2013, p6510-6512Journal Article, 2013, DOI , TARA - Full Text
• Gleeson, O, Gun'ko, YK, Connon, SJ, (S)-Proline-Derived Catalysts for the Acylative Kinetic Resolution of Alcohols: A Remote Structural Change Allows a Complete Selectivity Switch, SYNLETT, 24, (13), 2013, p1728-1734Journal Article, 2013, DOI
• Myles, L, Gathergood, N, Connon, SJ, The catalytic versatility of low toxicity dialkyltriazolium salts: in situ modification facilitates diametrically opposed catalysis modes in one pot, CHEMICAL COMMUNICATIONS, 49, (46), 2013, p5316-5318Journal Article, 2013, DOI
• Kavanagh, SA, Piccinini, A, Connon, SJ, The asymmetric synthesis of terminal aziridines by methylene transfer from sulfonium ylides to imines, ORGANIC & BIOMOLECULAR CHEMISTRY, 11, (21), 2013, p3535-3540Journal Article, 2013, DOI
• Gundala, S, Fagan, CL, Delany, EG, Connon, SJ, Organocatalytic Aerobic Oxidative Cleavage of Cyclic 1,2-Diketones, SYNLETT, 24, (10), 2013, p1225-1228Journal Article, 2013, DOI
• Curran, SP, Connon, SJ, The Thiolate-Catalyzed Intermolecular Crossed Tishchenko Reaction: Highly Chemoselective Coupling of Two Different Aromatic Aldehydes, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 51, (43), 2012, p10866-10870Journal Article, 2012, DOI
• Piccinini, A., Kavanagh, S.A., Connon, S, Highly enantioselective ylide-mediated synthesis of terminal epoxides, Chemical Communications , 48, (63), 2012, p7814-7816Journal Article, 2012, URL , TARA - Full Text
• Manoni, F, Cornaggia, C, Murray, J, Tallon, S, Connon, SJ, Catalytic, enantio- and diastereoselective synthesis of gamma-butyrolactones incorporating quaternary stereocentres, CHEMICAL COMMUNICATIONS, 48, (52), 2012, p6502-6504Journal Article, 2012, DOI , TARA - Full Text
• Cornaggia, C, Manoni, F, Torrente, E, Tallon, S, Connon, SJ, A Catalytic Asymmetric Reaction Involving Enolizable Anhydrides, ORGANIC LETTERS, 14, (7), 2012, p1850-1853Journal Article, 2012, DOI
• Palacio, C, Connon, SJ, A novel C-5 ' substituted cinchona alkaloid-derived catalyst promotes additions of alkyl thiols to nitroolefins with excellent enantioselectivity, CHEMICAL COMMUNICATIONS, 48, (23), 2012, p2849-2851Journal Article, 2012, DOI , TARA - Full Text
• Rodriguez-Docampo, Z, Quigley, C, Tallon, S, Connon, SJ, The Dynamic Kinetic Resolution of Azlactones with Thiol Nucleophiles Catalyzed by Arylated, Deoxygenated Cinchona Alkaloids, JOURNAL OF ORGANIC CHEMISTRY, 77, (5), 2012, p2407-2414Journal Article, 2012, DOI
• Curran, SP, Connon, SJ, Selenide Ions as Catalysts for Homo- and Crossed-Tishchenko Reactions of Expanded Scope, ORGANIC LETTERS, 14, (4), 2012, p1074-1077Journal Article, 2012, DOI
• Quigley, C, Rodriguez-Docampo, Z, Connon, SJ, Highly tunable arylated cinchona alkaloids as bifunctional catalysts, CHEMICAL COMMUNICATIONS, 48, (10), 2012, p1443-1445Journal Article, 2012, DOI , TARA - Full Text
• Rodriguez-Docampo, Z., Connon, S.J., Organocatalytic Asymmetric Additions to meso-Anhydrides and Azlactones , ChemCatChem , 4, (2), 2012, p151-168Journal Article, 2012, URL
• Lynam-Lennon, N., Maher, S.G., Maguire, A., (...), Reynolds, J.V., O'Sullivan, J., Altered mitochondrial function and energy metabolism is associated with a radioresistant phenotype in oesophageal adenocarcinoma, PLoS ONE , 9, (6), 2014, pe100738-Journal Article, 2014, DOI , TARA - Full Text

The design and synthesis of novel chiral organocatalysts (and immobilised versions thereof) for asymmetric transformations. Asymmetric bifunctional organocatalysis. Synthesis of novel cyclin-dependant kinase (CDK) inhibitors. Design of novel tetracycline derivatives to combat bacterial resistance. Novel synthetic methodology, including the scope expansion of several important carbon-carbon bond-forming reactions such as the asymmetric Baylis-Hillman reaction and ketone trifluoromethylation. The design of novel fast initiating olefin metathesis catalysts.

• Council Member of the Instite of Chemistry of Ireland 2005
• Member of the RSC Ireland Committee -