Dermot Kelleher
Adjunct Professor, School Office - Medicine
Adjunct Professor, Clinical Medicine

Publications and Further Research Outputs

Peer-Reviewed Publications

Coleman C, Quinn E.M, Ryan A.W, Conroy J, Trimble V, Mahmud N, Kennedy N, Corvin A.P, Morris D.W, Donohoe G, O'Morain C, MacMathuna P, Byrnes V, Kiat C, Trynka G, Wijmenga C, Kelleher D, Ennis S, Anney R.J.L, McManus R, Common polygenic variation in coeliac disease and confirmation of ZNF335 and NIFA as disease susceptibility loci, Molecular Psychiatry, 24, 2016, p291 - 297 Journal Article, 2016 URL TARA - Full Text DOI

Májer F, Sharma R, Mullins C, Keogh L, Phipps S, Duggan S, Kelleher D, Keely S, Long A, Radics G, Wang J, Gilmer JF, New highly toxic bile acids derived from deoxycholic acid, chenodeoxycholic acid and lithocholic acid., Bioorganic & medicinal chemistry, 22, (1), 2014, p256-68 Journal Article, 2014 TARA - Full Text DOI

McCarthy, S.E., Gillis, J., Kramer, M., (...), McCombie, W.R., Corvin, A. , De novo mutations in schizophrenia implicate chromatin remodeling and support a genetic overlap with autism and intellectual disability, Molecular Psychiatry, 19, 2014, p652-658 Journal Article, 2014 DOI TARA - Full Text

L.E. Collins, M Lynch, I Marszalowska, M. Kristek, K. Rochfort, M. O'Connell, H.J. Windle, D. Kelleher, C.E. Loscher, Surface layer proteins isolated from Clostridium difficile induce clearance responses in macrophages, Microbes and Infection, 2014 Journal Article, 2014 TARA - Full Text DOI

Ruiz, JFM, Kedziora, K, Pigott, M, Keogh, B, Windle, H, Gavin, J, Kelleher, DP, Gilmer, JF, A nitrophenyl-based prodrug type for colorectal targeting of prednisolone, budesonide and celecoxib, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 23, (6), 2013, p1693-1698 Journal Article, 2013 DOI

Grealy, R., White, M., Stordeur, P., Kelleher, D., Doherty, D.G., McManus, R., Ryan, T., Characterising cytokine gene expression signatures in patients with severe sepsis, Mediators of Inflammation, 2013, 2013, part. no. 164246 Journal Article, 2013 TARA - Full Text DOI

Queiroz, D.M.M., Harris, P.R., Sanderson, I.R., Windle, H.J., Walker, M.M., Rocha, A.M.C., Rocha, G.A., (...), Crabtree, J.E, Iron Status and Helicobacter pylori Infection in Symptomatic Children: An International Multi-Centered Study, PLoS ONE , 8, (7), 2013, art. no. e68833 Journal Article, 2013 TARA - Full Text DOI

Su, Z, Gay, LJ, Strange, A, Palles, C, Band, G, Whiteman, DC, Lescai, F, Langford, C, Nanji, M, Edkins, S, van der Winkel, A, Levine, D, Sasieni, P, Bellenguez, C, Howarth, K, Freeman, C, Trudgill, N, Tucker, AT, Pirinen, M, Peppelenbosch, MP, van der Laan, LJW, Kuipers, EJ, Drenth, JPH, Peters, WH, Reynolds, JV, Kelleher, DP, McManus, R, Grabsch, H, Prenen, H, Bisschops, R, Krishnadath, K, Siersema, PD, van Baal, JWPM, Middleton, M, Petty, R, Gillies, R, Burch, N, Bhandari, P, Paterson, S, Edwards, C, Penman, I, Vaidya, K, Ang, Y, Murray, I, Patel, P, Ye, WM, Mullins, P, Wu, AH, Bird, NC, Dallal, H, Shaheen, NJ, Murray, LJ, Koss, K, Bernstein, L, Romero, Y, Hardie, LJ, Zhang, R, Winter, H, Corley, DA, Panter, S, Risch, HA, Reid, BJ, Sargeant, I, Gammon, MD, Smart, H, Dhar, A, McMurtry, H, Ali, H, Liu, G, Casson, AG, Chow, WH, Rutter, M, Tawil, A, Morris, D, Nwokolo, C, Isaacs, P, Rodgers, C, Ragunath, K, MacDonald, C, Haigh, C, Monk, D, Davies, G, Wajed, S, Johnston, D, Gibbons, M, Cullen, S, Church, N, Langley, R, Griffin, M, Alderson, D, Deloukas, P, Hunt, SE, Gray, E, Dronov, S, Potter, SC, Tashakkori-Ghanbaria, A, Anderson, M, Brooks, C, Blackwell, JM, Bramon, E, Brown, MA, Casas, JP, Corvin, A, Duncanson, A, Markus, HS, Mathew, CG, Palmer, CNA, Plomin, R, Rautanen, A, Sawcer, SJ, Trembath, RC, Viswanathan, AC, Wood, N, Trynka, G, Wijmenga, C, Cazier, JB, Atherfold, P, Nicholson, AM, Gellatly, NL, Glancy, D, Cooper, SC, Cunningham, D, Lind, T, Hapeshi, J, Ferry, D, Rathbone, B, Brown, J, Love, S, Attwood, S, MacGregor, S, Watson, P, Sanders, S, Ek, W, Harrison, RF, Moayyedi, P, de Caestecker, J, Barr, H, Stupka, E, Vaughan, TL, Peltonen, L, Spencer, CCA, Tomlinson, I, Donnelly, P, Jankowski, JAZ, Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus, NATURE GENETICS, 44, (10), 2012, p1131-+ Journal Article, 2012 DOI

Verma, N.K., Conroy, J., Lyons, P.E., Coleman, J., O'Sullivan, M.P., Kornfeld, H., Kelleher, D., Volkov, Y., Autophagy induction by silver nanowires: A new aspect in the biocompatibility assessment of nanocomposite thin films, Toxicology and Applied Pharmacology, 164, (3), 2012, p451-461 Journal Article, 2012 DOI

O'Riordan AA, Morales VA, Mulligan L, Faheem N, Windle HJ, Kelleher DP, Alkyl hydroperoxide reductase: a candidate Helicobacter pylori vaccine., Vaccine, 30, (26), 2012, p3876-84 Journal Article, 2012 DOI

Ruiz, JFM, Kedziora, K, O'Reilly, M, Maguire, J, Keogh, B, Windle, H, Kelleher, DP, Gilmer, JF, Azo-reductase activated budesodine prodrugs for colon targeting, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 22, (24), 2012, p7573-7577 Journal Article, 2012 DOI

Byrne AM, Sharma R, Duggan G, Kelleher D, Long A, Deoxycholic acid impairs glycosylation and fucosylation processes in esophageal epithelial cells., Glycobiology, 22, (5), 2012, p638-648 Journal Article, 2012 DOI

Freeley M, O'Dowd F, Paul T, Kashanin D, Davies A, Kelleher D, Long A, L-plastin regulates polarization and migration in chemokine-stimulated human T lymphocytes., Journal of immunology (Baltimore, Md. : 1950), 188, (12), 2012, p6357-6370 Journal Article, 2012 DOI

Petrovic D, Dempsey E, Doherty DG, Kelleher D, Long A, Hepatitis C virus - T-cell responses and viral escape mutations., European journal of immunology, 42, (1), 2012, p17-26 Journal Article, 2012 DOI

Kelleher, D., Dendrimers branch out to support mucosal integrity, EMBO Molecular Medicine , 4, (9), 2012, p860-862 Journal Article, 2012 DOI

Gavin, J, Ruiz, JFM, Kedziora, K, Windle, H, Kelleher, DP, Gilmer, JF, Structure requirements for anaerobe processing of azo compounds: Implications for prodrug design, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 22, (24), 2012, p7647-7652 Journal Article, 2012 DOI

Verma NK, Dempsey E, Long A, Davies A, Barry SP, Fallon PG, Volkov Y, Kelleher D, Leukocyte function-associated antigen-1/intercellular adhesion molecule-1 interaction induces a novel genetic signature resulting in T-cells refractory to transforming growth factor-ß signaling., The Journal of biological chemistry, 287, (32), 2012, p27204-16 Journal Article, 2012 DOI

Mohamed BM, Verma NK, Davies AM, McGowan A, Crosbie-Staunton K, Prina-Mello A, Kelleher D, Botting CH, Causey CP, Thompson PR, Pruijn GJ, Kisin ER, Tkach AV, Shvedova AA, Volkov Y, Citrullination of proteins: a common post-translational modification pathway induced by different nanoparticles in vitro and in vivo., Nanomedicine (London, England), 7, (8), 2012, p1181-1195 Journal Article, 2012 DOI

Sharma R, Prichard D, Majer F, Byrne AM, Kelleher D, Long A, Gilmer JF, Ursodeoxycholic acid amides as novel glucocorticoid receptor modulators., Journal of medicinal chemistry, 54, (1), 2011, p122-130 Journal Article, 2011 DOI

Fitzmaurice K, Petrovic D, Ramamurthy N, Simmons R, Merani S, Gaudieri S, Sims S, Dempsey E, Freitas E, Lea S, McKiernan S, Norris S, Long A, Kelleher D, Klenerman P, Molecular footprints reveal the impact of the protective HLA-A*03 allele in hepatitis C virus infection., Gut, 60, (11), 2011, p1563-71 Journal Article, 2011 DOI TARA - Full Text

Mohamed BM, Verma NK, Prina-Mello A, Williams Y, Davies AM, Bakos G, Tormey L, Edwards C, Hanrahan J, Salvati A, Lynch I, Dawson K, Kelleher D, Volkov Y, Activation of stress-related signalling pathway in human cells upon SiO2 nanoparticles exposure as an early indicator of cytotoxicity., Journal of nanobiotechnology, 9, 2011, p29 Journal Article, 2011 DOI

Marquez Ruiz JF, Kedziora K, Keogh B, Maguire J, Reilly M, Windle HJ, Kelleher D, Gilmer JF, A double prodrug system for colon targeting of benzenesulfonamide COX-2 inhibitors, Bioorganic & Medicinal Chemistry Letters, 21, (22), 2011, p6636-6640 Journal Article, 2011 TARA - Full Text

White M, Martin-Loeches I, Lawless MW, O'Dwyer MJ, Doherty DG, Young V, Kelleher D, McManus R, Ryan T, Hospital-acquired pneumonia after lung resection surgery is associated with characteristic cytokine gene expression., Chest, 139, (3), 2011, p626-32 Journal Article, 2011 DOI

Anthony Ryan, Mark Lynch, Sinead M. Smith, Sylvie Amu, Hendrik J. Nel, Claire E. McCoy, Jennifer K. Dowling, Eve Draper, Vincent O'Reilly, Ciara McCarthy, Julie O'Brien, Déirdre Ní Eidhin, Mary J. O'Connell, Brian Keogh, Charles O. Morton, Thomas R. Rogers, Padraic G. Fallon, Luke A. O'Neill, Dermot Kelleher, Christine E. Loscher , A Role for TLR4 in Clostridium difficile Infection and the Recognition of Surface Layer Proteins, PLoS Pathogens, 7, (6, e1002076), 2011 Journal Article, 2011 TARA - Full Text

Ruiz JF, Kedziora K, Keogh B, Maguire J, Reilly M, Windle H, Kelleher DP, Gilmer JF, A double prodrug system for colon targeting of benzenesulfonamide COX-2 inhibitors., Bioorganic & medicinal chemistry letters, 21, (22), 2011, p6636-40 Journal Article, 2011 DOI

Freeley, M., Kelleher, D. and Long, A. , Regulation of Protein Kinase C function by phosphorylation on conserved and non-conserved sites, Cellular Signalling, 23, (5), 2011, p753-762 Journal Article, 2011 TARA - Full Text

Bashir Mustafa Mohamed, Navin Kumar Verma, Adriele Prina-Mello, Yvonne Williams, Anthony M Davies, Gabor Bakos, Laragh Tormey, Connla Edwards, John Hanrahan, Anna Salvati, Iseult Lynch, Kenneth Dawson, Dermot Kelleher, and Yuri Volkov, Activation of stress-related signalling pathway in human cells upon SiO2 nanoparticles exposure as an early indicator of cytotoxicity, Journal of Nanobiotechnology, 9, 2011, p29- Journal Article, 2011 TARA - Full Text

Petrovic D., Stamataki Z., Dempsey E., Golden-Mason L., Freeley M., Doherty D., Prichard D., Keogh C., Conroy J., Mitchell S., Volkov Y., McKeating J.A., O'Farrelly C., Kelleher D., Long A., Hepatitis C virus targets the Tcell secretory machinery as a mechanism of immune evasion, Hepatology, 53, (6), 2011, p1846 - 1853 Journal Article, 2011 DOI URL

Duggan S, Prichard D, Kirca M, Kelleher D, Inherited Syndromes Predisposing to Inflammation and GI Cancer., Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer, 185, 2011, p35-50 Journal Article, 2011

White M, Mahon V, Grealy R, Doherty DG, Stordeur P, Kelleher DP, McManus R, Ryan T, Post-operative infection and sepsis in humans is associated with deficient gene expression of Yc cytokines and their apoptosis mediators., Critical Care (London, England), 15, (3), 2011, pR158 Journal Article, 2011 TARA - Full Text DOI URL

di Iulio J, Ciuffi A, Fitzmaurice K, Kelleher D, Rotger M, Fellay J, Martinez R, Pulit S, Furrer H, Günthard HF, Battegay M, Bernasconi E, Schmid P, Hirschel B, Barnes E, Klenerman P, Telenti A, Rauch A, Estimating the net contribution of interleukin-28B variation to spontaneous hepatitis C virus clearance., Hepatology (Baltimore, Md.), 53, (5), 2011, p1446-1454 Journal Article, 2011 DOI

Ruiz JF, Kedziora K, Windle H, Kelleher DP, Gilmer JF, Investigation into drug release from colon-specific azoreductase-activated steroid prodrugs using in-vitro models., The Journal of pharmacy and pharmacology, 63, (6), 2011, p806-816 Journal Article, 2011 DOI

Carroll, TP, O'Connor, CA, Floyd, O, McPartlin, J, Kelleher, DP, O'Brien, G, Dimitrov, BD, Morris, VB, Taggart, CC, McElvaney, NG, The prevalence of alpha-1 antitrypsin deficiency in Ireland, RESPIRATORY RESEARCH, 12, (91), 2011 Journal Article, 2011 TARA - Full Text

Verma NK, Dempsey E, Freeley M, Botting CH, Long A, Kelleher D, Volkov Y, Analysis of dynamic tyrosine phosphoproteome in LFA-1 triggered migrating T-cells., Journal of Cellular Physiology, 226, (6), 2011, p1489-1498 Journal Article, 2011 DOI TARA - Full Text

Paszko E, Ehrhardt C, Senge MO, Kelleher DP, Reynolds JV, Nanodrug applications in photodynamic therapy., Photodiagnosis and photodynamic therapy, 8, (1), 2011, p14-29 Journal Article, 2011 TARA - Full Text DOI

Merani S, Petrovic D, James I, Chopra A, Cooper D, Freitas E, Rauch A, di Iulio J, John M, Lucas M, Fitzmaurice K, McKiernan S, Norris S, Kelleher D, Klenerman P, Gaudieri S, Effect of immune pressure on hepatitis C virus evolution: insights from a single-source outbreak., Hepatology (Baltimore, Md.), 53, (2), 2011, p396-405 Journal Article, 2011 DOI

Smith SM, Moran AP, Duggan SP, Ahmed SE, Mohamed AS, Windle HJ, O'Neill LA, Kelleher DP, Tribbles 3: a novel regulator of TLR2-mediated signaling in response to Helicobacter pylori lipopolysaccharide., Journal of immunology (Baltimore, Md. : 1950), 186, (4), 2011, p2462-2671 Journal Article, 2011 DOI

Sharma R, Majer F, Peta VK, Wang J, Keaveney R, Kelleher D, Long A, Gilmer JF, Bile acid toxicity structure-activity relationships: correlations between cell viability and lipophilicity in a panel of new and known bile acids using an oesophageal cell line (HET-1A)., Bioorganic & medicinal chemistry, 18, (18), 2010, p6886-95 Journal Article, 2010

White M, Lawless MW, O'Dwyer MJ, Grealy R, O'Connell B, Stordeur P, Kelleher D, McManus R*, Ryan T*, Transforming Growth Factor beta-1 and Interleukin-17 gene transcription in peripheral blood mononuclear cells and the human response to infection, Cytokine, 50, 2010, p322 - 327 Journal Article, 2010 DOI

Dubois PC, Trynka G, Franke L, Hunt KA, Romanos J, Curtotti A, Zhernakova A, Heap GA, Adány R, Aromaa A, Bardella MT, van den Berg LH, Bockett NA, de la Concha EG, Dema B, Fehrmann RS, Fernández-Arquero M, Fiatal S, Grandone E, Green PM, Groen HJ, Gwilliam R, Houwen RH, Hunt SE, Kaukinen K, Kelleher D, Korponay-Szabo I, Kurppa K, MacMathuna P, Mäki M, Mazzilli MC, McCann OT, Mearin ML, Mein CA, Mirza MM, Mistry V, Mora B, Morley KI, Mulder CJ, Murray JA, Núñez C, Oosterom E, Ophoff RA, Polanco I, Peltonen L, Platteel M, Rybak A, Salomaa V, Schweizer JJ, Sperandeo MP, Tack GJ, Turner G, Veldink JH, Verbeek WH, Weersma RK, Wolters VM, Urcelay E, Cukrowska B, Greco L, Neuhausen SL, McManus R, Barisani D, Deloukas P, Barrett JC, Saavalainen P, Wijmenga C, van Heel DA, Multiple common variants for celiac disease influencing immune gene expression., Nature genetics, 42, (4), 2010, p295-302 Journal Article, 2010

Freeley M, Bakos G, Davies A, Kelleher D, Long A, Dunican DJ, A high-content analysis toolbox permits dissection of diverse signaling pathways for T lymphocyte polarization., Journal of biomolecular screening : the official journal of the Society for Biomolecular Screening, 15, (5), 2010, p541 - 555 Journal Article, 2010 DOI URL

Kozak K, Bakos G, Hoff A, Bennett E, Dunican D, Davies A, Kelleher D, Long A, Csucs G, Workflow-based software environment for large-scale biological experiments., Journal of biomolecular screening : the official journal of the Society for Biomolecular Screening, 15, (7), 2010, p892-9 Journal Article, 2010 DOI

Windle HJ, Brown PA, Kelleher DP, Proteomics of bacterial pathogenicity: therapeutic implications., Proteomics. Clinical applications, 4, (2), 2010, p215-27 Journal Article, 2010

Dubois PCA, Trynka G, Franke L, Hunt KA, Romanos J, Curtotti A, Zhernakova A, Heap GA, Ádány R, Aromaa A, Bardella MT, van den Berg LH, Bockett NA, de la Concha EG, Dema B, Fehrmann RS, Fernández-Arquero M, Fiatal S, Grandone E, Green PM, Groen HJ, Gwilliam R, Houwen RH, Hunt SE, Kaukinen K, Kelleher D, Korponay-Szabo I, Kurppa K, MacMathuna P, Mäki M, Mazzilli MC, McCann OT, Mearin ML, Mein CA, Mirza MM, Mistry V, Mora B, Morley KI, Mulder CJ, Murray JA, Núñez C, Oosterom E, Ophoff RA, Polanco I, Peltonen L, Platteel M, Rybak A, Salomaa V, Schweizer JJ, Sperandeo MP, Tack GJ, Turner G, Veldink JH, Verbeek , Weersma RK, Wolters VM, Urcelay E, Cukrowska B, Greco L, Neuhausen SL, McManus R, Barisani D, Deloukas P, Barrett JC, Saavalainen P, Wijmenga C, van Heel DA, Multiple common variants for celiac disease influencing immune gene expression, Nature Genetics, 42, (4), 2010, p295 - 302 Journal Article, 2010 URL DOI TARA - Full Text

Duggan SP, Behan FM, Kirca M, Smith S, Reynolds JV, Long A, Kelleher D, An integrative genomic approach in oesophageal cells identifies TRB3 as a bile acid responsive gene, down regulated in Barrett's oesophagus, which regulates NF-kB activation and cytokine levels., Carcinogenesis, 5, 2010, p936 - 945 Journal Article, 2010 URL DOI

Brophy K*, Ryan AW*, Turner G, Trimble V, Patel KD, O'Morain C, Kennedy NP, Egan B, Close E, Lawlor G, MacMathuna P, Stevens FM, Abuzakouk M, Feighery C, Kelleher D, McManus R, Evaluation of 6 candidate genes on chromosome 11q23 for coeliac disease susceptibility: a case control study, BMC Medical Genetics, 11, (76), 2010 Journal Article, 2010 TARA - Full Text URL

Byrne AM, Foran E, Sharma R, Davies A, Mahon C, O'Sullivan J, O'Donoghue D, Kelleher D, Long A, Bile acids modulate the Golgi membrane fission process via a protein kinase Ceta and protein kinase D-dependent pathway in colonic epithelial cells., Carcinogenesis, 31, (4), 2010, p737-744 Journal Article, 2010 DOI

Ruchika Sharma, Ferenc Majer, Vijaya Kumar Peta, Jun Wang, Ray Keaveney, Dermot Kelleher, Aideen Long and John F. Gilmer, Bile acid toxicity structure activity relationships: Correlations between cell viability and lipophilicity in a panel of new and known bile acids using an esophageal cell line (HET-1A), Bioorganic & Medicinal Chemistry, 18, (18), 2010, p6886-6895 Journal Article, 2010 TARA - Full Text

White M, Lawless MW, O'Dwyer MJ, Grealy R, Connell BO, Stordeur P, Kelleher D, McManus R, Ryan T, Transforming growth factor beta-1 and interleukin-17 gene transcription in peripheral blood mononuclear cells and the human response to infection., Cytokine, 50, (3), 2010, p322-7 Journal Article, 2010

Birmingham A, Selfors LM, Forster T, Wrobel D, Kennedy CJ, Shanks E, Santoyo-Lopez J, Dunican DJ, Long A, Kelleher D, Smith Q, Beijersbergen RL, Ghazal P, Shamu CE, Statistical methods for analysis of high-throughput RNA interference screens, Nat Methods, 6, (8), 2009, p569 - 575 Journal Article, 2009

Dazert E, Neumann-Haefelin C, Bressanelli S, Fitzmaurice K, Kort J, Timm J, McKiernan S, Kelleher D, Gruener N, Tavis JE, Rosen HR, Shaw J, Bowness P, Blum HE, Klenerman P, Bartenschlager R, Thimme R., Loss of viral fitness and cross-recognition by CD8+ T cells limit HCV escape from a protective HLA-B27-restricted human immune response, The Journal of Clinical Investigation, 119, (2), 2009, p376 - 386 Journal Article, 2009 TARA - Full Text DOI

Babar M, Abdel-Latif MM, Ravi N, Murphy A, Byrne PJ, Kelleher D, Reynolds JV., Pilot translational study of dietary vitamin C supplementation in Barrett's esophagus., Dis Esophagus, 23, (3), 2009 Journal Article, 2009

Mankan, A.K., Lawless, M.W., Gray, S.G., Kelleher, D., McManus, R., NF-κB regulation: The nuclear response , Journal of Cellular and Molecular Medicine , 13, (4), 2009, p631-643 Journal Article, 2009 TARA - Full Text

Williams Y., Sukhanova A., Nowostawska M., Davies A.M., Mitchell S., Oleinikov V., Gun'ko Y., Nabiev I., Kelleher D., Volkov Y., Probing cell-type-specific intracellular nanoscale carriers using size-tuned quantum dots, Small, 5, (22), 2009, p2581 - 2588 Journal Article, 2009 DOI

Ruiz JF, Radics G, Windle H, Serra HO, Simplicio AL, Kedziora K, Fallon PG, Kelleher DP, Gilmer JF., Design, synthesis and pharmacological effects of a cyclization-activated steroid prodrug for colon targeting in inflammatory bowel disease., J Med Chem, 52, (10), 2009, p3205 - 3211 Journal Article, 2009

Williams Y, Sukhanova A, Nowostawska M, Davies AM, Mitchell S, Oleinikov V, Gun'ko Y, Nabiev I, Kelleher D, Volkov Y., Probing cell-type-specific intracellular nanoscale barriers using size-tuned quantum dots., Small, 5, (22), 2009, p2581 - 2588 Journal Article, 2009

Abdel-Latif MM, Windle HJ, Davies A, Volkov Y, Kelleher D., Inflammation and esophageal carcinogenesis., Curr Opin Pharmacol, 9, (4), 2009, p396 - 404 Journal Article, 2009

Patel KD, Duggan SP, Currid CA, Gallagher WM, McManus R, Kelleher D, Murphy RT, Ryan AW., High sensitivity cytokine detection in acute coronary syndrome reveals up-regulation of Interferon Gamma and Interleukin-10 post myocardial infarction., Clinical Immunology, 133, (2), 2009, p251 - 256 Journal Article, 2009

Verma NK, Dourlat J, Davies AM, Long A, Liu WQ, Garbay C, Kelleher D, Volkov Y. , STAT3-stathmin interactions control microtubule dynamics in migrating T-cells., J Biol Chem, 284, (18), 2009, p12349 - 12362 Journal Article, 2009

Ruiz Marquez JF, Radics G, Windle H, Serra HO, Simplicio AL, Kedziora K, Fallon PG, Kelleher DP, Gilmer GF, Design, Synthesis, and Pharmacological Effects of a Cyclization-activated Steroid Prodrug for Colon Targeting in Inflammatory Bowel Disease, Journal of Medicinal Chemistry, 52, (10), 2009, p3205 - 3211 Journal Article, 2009 DOI

Patel KD, Murphy RT, White M, Gasparrow D, Kelleher DP, Ryan T, McManus R, Ryan AW., Interleukin 17: an unlikely marker of acute coronary syndrome?, Atherosclerosis, 205, (1), 2009, p33 - 34 Journal Article, 2009

Looby E, Abdel-Latif MM, Athié-Morales V, Duggan S, Long A, Kelleher D., Deoxycholate induces COX-2 expression via Erk1/2 - p38-MAPK and AP-1-dependent mechanisms in esophageal cancer cells, BMC Cancer, 9, (190), 2009 Journal Article, 2009 TARA - Full Text DOI

Verma NK, Dempsey E, Conroy J, Olwell P, Mcelligott AM, Davies AM, Kelleher D, Butini S, Campiani G, Williams DC, Zisterer DM, Lawler M, Volkov Y., A new microtubule-targeting compound PBOX-15 inhibits T-cell migration via post-translational modifications of tubulin., Journal of Molecular Medicine, 86, (4), 2008, p457-469 Journal Article, 2008 DOI

O'Dwyer MJ, Mankan AK, Stordeur P, White W, Lawless MW, O'Connell B, Kelleher D, McManus R*, Ryan T* , Variability in IL-23 and IL-27 gene expression may determine patient response to a septic insult, Intensive Care Medicine, 34, (4), 2008, p683 - 691 Journal Article, 2008 DOI

Hunt KA, Zhernakova A, Turner G, Heap GA, Franke L, Bruinenberg M, Romanos J, Dinesen LC, Ryan AW, Panesar D, Gwilliam R,Takeuchi F, McLaren WM, Holmes GK, Howdle PD, Walters JR, Sanders DS, Playford RJ, Trynka G, Mulder CJ, Mearin ML,Verbeek WH, Trimble V, Stevens FM, O'Morain C, Kennedy NP, Kelleher D, Pennington DJ, Strachan DP, McArdle WL, Mein CA,Wapenaar MC, Deloukas P, McGinnis R, McManus R*, Wijmenga C*, van Heel DA*., Newly identified genetic risk variants for celiac disease related to the immune response., Nature Genetics, 40, 2008, p395-402 Journal Article, 2008 DOI TARA - Full Text

O'Dwyer MJ, Mankan AK, Stordeur P, White W, Lawless MW, O'Connell B, Kelleher D, McManus R*, Ryan T*. , The human response to infection is associated with distinct patterns of interleukin 23 and interleukin 27 expression, Intensive Care Medicine, 34, (4), 2008, p683-691 Journal Article, 2008 DOI

Conroy J, Byrne SJ, Gun'ko YK, Rakovich YP, Donegan JF, Davies A, Kelleher D, Volkov Y., CdTe Nanoparticles Display Tropism to Core Histones and Histone-Rich Cell Organelles, Small, 4, (11), 2008, 2006-2015 Journal Article, 2008 DOI

Igor Nabiev, Siobhan Mitchell, Anthony Davies, Yvonne Williams, Dermot Kelleher, Richard Moore, Yurii K. Gun'ko, Stephen Byrne, Yury P. Rakovich, John F. Donegan, Alyona Sukhanova, Jennifer Conroy, David Cottell, Nikolai Gaponik, Andrey Rogach and Yuri Volkov, Non-Functionalized Nanocrystals Can Exploit a Cell's Active Transport Machinery Delivering Them to Specific Nuclear and Cytoplasmic Compartments, NanoLetters , 7, 2007, p3452-3461 Journal Article, 2007 DOI URL

Azim K, McManus R, Brophy K, Ryan A, Kelleher D, Reynolds JV, Genetic Polymorphisms and the Risk of Infection Following Esophagectomy , Annals of Surgery, 246, (1), 2007, p122 - 128 Journal Article, 2007 DOI

Duggan E, O'Dwyer M, Caraher E, Diviney D, McGovern E, Kelleher D, McManus R, Ryan T, Coagulopathy After Cardiac Surgery May Be Influenced by a Functional Plasminogen Activator Inhibitor Polymorphism, Anesthesia & Analgesia , 104, (6), 2007, p1343 - 1347 Journal Article, 2007 TARA - Full Text DOI

Smyth CM, McKiernan SM, Hagan R, Pilkington R, O'Regan M, Lawlor E, Kelleher D., Chronic hepatitis C infection and sicca syndrome: a clear association with HLA DQB1*02, European Journal of Gastroenterology and Hepatology, 19, (6), 2007, p493 - 498 Journal Article, 2007

Nabiev, I, Mitchell, S, Davies, A, Williams, Y, Kelleher, D, Moore, R, Gun'ko, YK, Byrne, S, Rakovich, YP, Donegan, JF, Sukhanova, A, Conroy, J, Cottell, D, Gaponik, N, Rogach, A, Volkov, Y, Nonfunctionalized nanocrystals can exploit a cell's active transport machinery delivering them to specific nuclear and cytoplasmic compartments, Nano Letters, 7, (11), 2007, p3452-3461 Journal Article, 2007 DOI

van Heel DA, Franke L, Hunt KA, Gwilliam R, Zhernakova A, Inouye M, Wapenaar MC, Barnardo MC, Bethel G, Holmes GK, Feighery C, Jewell D, Kelleher D, Kumar P, Travis S, Walters JR, Sanders DS, Howdle P, Swift J, Playford RJ, McLaren WM, Mearin ML, Mulder CJ, McManus R, McGinnis R, Cardon LR, , A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21., Nature Genetics, 39, (7), 2007, p827 - 829 Journal Article, 2007 DOI TARA - Full Text

Windle HJ, Kelleher D, Crabtree JE, Childhood Helicobacter pylori infection and growth impairment in developing countries: a vicious cycle?, Paediatrics, 119, (3), 2007, pe754 - e759 Journal Article, 2007 DOI

Goulding C, O'Brien C, Egan H, Hegarty JE, McDonald G, O'Farrelly C, White B, Kelleher D, Norris S, The impact of inherited prothrombotic risk factors on individuals chronically infected with hepatitis C virus from a single source., Journal of Viral Hepatology, 14, (4), 2007, p255 - 259 Journal Article, 2007

Volkov Y, Long A, Freeley M, Golden-Mason L, O'Farrelly C, Murphy A, Kelleher D, The hepatitis C envelope 2 protein inhibits LFA-1 transduced protein kinase C signalling for T lymphocyte migration, Gastroenterology, 130, (2), 2006, p482 - 492 Journal Article, 2006

Megan M Dring, Carol A Goulding, Valerie I Trimble, Denise Keegan, Anthony W Ryan, Karen M Brophy, Claire M Smyth, P. W. Napoleon Keeling, Diarmuid O'Donoghue, Maria O'Sullivan, Colm O'Morain, Nasir Mahmud, Ann-CharlotteWikström, Dermot Kelleher, Ross McManus , The Pregnane X Receptor Locus is Associated with susceptibility to inflammatory bowel disease, 2006, p341 - 348 Journal Article, 2006

Deirdre Ni Eidhin, Anthony W Ryan, Rachael M Doyle, J Bernard Walsh, Dermot Kelleher, Sequence and phylogenetic analysis of the gene for surface layer protein, slpA, from 14 PCR ribotypes of Clostridium difficile, Journal of Medical Microbiology, 55, (1), 2006, p69 - 83 Journal Article, 2006 DOI

Dring MM, Goulding CA, Trimble VI, Keegan D, Ryan AW, Brophy KM, Smyth CM, Keeling PWN, O'Donoghue D, O'Sullivan M, O'Morain C, Mahmud N, Wikström A-C, Kelleher D, McManus R., The Pregnane X Receptor Locus is Associated with susceptibility to inflammatory bowel disease., Gastroenterology, 130, (2), 2006, p341 - 348 Journal Article, 2006 DOI

O'Dwyer MJ, Mankan AK, Stordeur P, O'Connell B, Duggan E, White M, Kelleher DP, McManus R, Ryan T, The occurrence of severe sepsis is related to distinct patterns of cytokine gene expression, Shock, 26, (6), 2006, p544 - 550 Journal Article, 2006 DOI

Volkov Y, Long A, Freeley M, Golden-Mason L, O'Farrelly C, Murphy A, Kelleher D, The hepatitis C envelope 2 protein inhibits LFA-1-tranduced protein kinase C signalling for T lymphocyte migration, Gastroenterology, 130, (2), 2006, p482 - 492 Journal Article, 2006

O'Dwyer MJ, Mankan AK, Stordeur P, O'Connell B, Duggan E, White M, Kelleher DP, McManus R, Ryan T., The occurrence of severe sepsis and septic shock are related to distinct patterns of cytokine gene expression., Shock, 26, (6), 2006, p544 - 550 Journal Article, 2006

Abuzakouk M, Fitzgerald AP, McLoughlin RM, O'Morain C, Kennedy NP, Stevens FM, Feighery C, Kelleher D, McManus R, Haplotypes in the CTLA4 region are associated with coeliac disease in the Irish population, Genes Immun, 7, (1), 2006, p19 - 26 Journal Article, 2006

Duggan E, Caraher E, Gately C, O'Dwyer M, McGovern E, Kelleher D, McManus R, Ryan T, Tumour necrosis factor alpha and Interleukin10 gene expression after cardiac surgery: The protective role of Interleukin 10, Critical Care Medicine , 34, (8), 2006, p2134 - 2139 Journal Article, 2006 DOI

Duggan E, Caraher E, Gately K, O'Dwyer M, McGovern E, Kelleher D, McManus R, Ryan T., Tomour necrosis factor-alpha and interleukin-10 gene expression in peripheral blood mononuclear cells after cardiac surgery, Critical Care Medicine, 34, (8), 2006, p2134 - 2139 Journal Article, 2006

O'Dwyer MJ, Dempsey F, Crowley V, Kelleher D, McManus R, Ryan T., Septic shock correlates with ADMA levels which may be influenced by a polymorphism in DDAH II: a prospective observational study, Critical Care, 10, (5), 2006, pR139 article number Journal Article, 2006 DOI

Levine RA, Sanderson SO, Ploutz-Snyder R, Murray F, Kay E, Hegarty J, Nolan N, Kelleher D, McDonald G, O'Keane JC, Drowe J, Assessment of fibrosis progression in untreated Irish women with chronic hepatitis C contracted from immunoglobulin anti-D, Clinical Gastroenterology and Hepatology, 4, (10), 2006, p1271 - 1277 Journal Article, 2006

O'Dwyer MJ, Dempsey F, Crowley V, Kelleher DP, McManus R, Ryan T., Septic shock is correlated with asymmetrical dimethyl arginine levels, which may be influenced by a polymorphism in the dimethylarginine dimethylaminohydrolase II gene: a prospective observational study., Critical Care, 10, (5), 2006, pR139 Journal Article, 2006 TARA - Full Text DOI

Duggan SP, Gallagher WM, Fox EJ, Abdel-Latif MM, Reynolds JV, Kelleher D., Low pH results in co-ordinate regulation of gene expression in oesophageal cells, Carcinogenesis, 27, (2), 2006, p319 - 327 Journal Article, 2006 TARA - Full Text DOI

K Brophy, AW Ryan, JM Thornton, M Abuzakouk, AP Fitzgerald, RM McLoughlin, C O'Morain, NP Kennedy, FM Stevens, C Feighery, D Kelleher, R McManus, Haplotypes in the CTLA4 region are associated with coeliac disease in the Irish population, Genes and Immunity, 7, (1), 2006, p19 - 26 Journal Article, 2006

El Din El Homasany B.S., Volkov Y., Takahashi M., Ono Y., Keryer G., Delouvée A., Looby E., Long A., Kelleher D., The scaffolding protein CG-NAP/AKAP450 is a critical integrating component of the LFA-1-induced signaling complex in migratory T cells, Journal of Immunology, 175, (12), 2006, p7811 - 7818 Journal Article, 2006 TARA - Full Text

Mechanisms of steroid action and resistance in inflammatory bowel disease. in, editor(s)Jewell DP, Colombel, JF, Pena AS, Tromm A, Warren BS , Colitis: Diagnosis and Therapeutic Strategies, Falk Symposia, Kluwer Academic Publishers, 2006, pp87-97 , [Kelleher D, McManus R.] Book Chapter, 2006

Ryan AW, Mapp J, Moyna S, Mattiangeli V, Kelleher D, Bradley DG, McManus R, Levels of inter-population differentiation among different functional classes of immunologically important genes, Genes and Immunity, 7, (2), 2006, p179 - 183 Journal Article, 2006 DOI

Mechanisms of steroid action and resistance in inflammatory bowel disease in, editor(s)DP Jewell, J-F Colombel, AS Pena, A Tromm, BF Warren , Colitis: Diagnosis and Therapeutic Strategies, Netherlands, Springer, 2006, pp87 - 97, [D Kelleher, R McManus] Book Chapter, 2006

Foran E, McWilliam P, Kelleher D, Croke DT, Long A, The leukocyte protein L-plastin induces proliferation, invasion and loss of E-cardherin expression in colon cancer cells, International Journal of Cancer, 118, (8), 2006, p2098 - 2104 Journal Article, 2006

Ryan R*, Thornton J*, Duggan E, McGovern E, O'Dwyer MJ, Ryan AW, Kelleher D, McManus R, Ryan T, Gene polymorphism and requirement for vasopressor infusion after cardiac surgery, Annals of Thoracic Surgery, 82, (3), 2006, p895 - 901 Journal Article, 2006 DOI

Ryan R, Thornton J, Dugan E, McGovern E, O'Dwyer MJ, Ryan AW, Kelleher D, McManus R, Ryan T, Gene polymorphism and requirement for vasopressor infusion after cardiac surgery, Annals of Thoracic Surgery, 82, (3), 2006, p895 - 901 Journal Article, 2006

Shah SA, Volkov Y, Arfin Q, Abdel-Latif MM, Kelleher D, Ursodeoxycholic acid inhibits interleukin beta 1 and deoxycholic acid-induced activation of NF-kappaB and AP-1 in human colon cancer cells, International Journal of Cancer, 1, (118(3)), 2006, p532 - 539 Journal Article, 2006

Neumann-Haefelin C, McKiernan S, Ward S, Viazov S, Spangenberg HC, Killinger T, Baumert TF, Nazarova N, Sheridan I, Pybus O, von Weizsacker F, Roggendorf M, Kelleher D, Klenerman P, Blum HE, Thimme R, Dominant influence of an HLA-B27 restricted CD8+ T cell response in mediating HCV clearance and evolution, Hepatology, 22, (43(3)), 2006, p563 - 572 Journal Article, 2006

Brophy K, Ryan AW, Thornton JM, Daly JS, McLoughlin R, O' Morain C, Abuzakouk M, Kennedy NP, Stevens FM, Feighery C, Kelleher D, McManus R, Haplotypes in the CTLA4 region are associated with coeliac disease in the Irish population., Genes and Immunity, 7, (1), 2006, p19 - 26 Journal Article, 2006 DOI

Abdel-Latif MM, Windle H, Terres A, NiEidhin DN, Kelleher D, Reynolds JV, Helicobacter pylori extract induces nuclear factor-kappa B, activator protein-1, and cyclooxygenase-2 in esophageal epithelial cells, Journal of Gastrointestinal Surgery, 10, (4), 2006, p551 - 562 Journal Article, 2006

Shah SA, Mahmud N, Mftah M, Roche HM, Kelleher D, Chronic but not acute conjugated linoleic acid treatment inhibits deoxycholic acid-induced protein kinase C and nuclear factor-kappaB activation in human colorectal cancer cells, European Journal of Cancer Prevention , 15, (2), 2006, p125 - 133 Journal Article, 2006

MMM Abdel-Latif, JM O'Riordan, N Ravi, D Kelleher, JV Reynolds, Activated nuclear factor-kappa B and cytokine profiles in the esophagus parallel tumor regression following neoadjuvant chemoradiotherapy, Diseases of the Esophagus, 18, 2005, p246 - 252 Journal Article, 2005

MMM Abdel-Latif, AA Raouf, K Sabra, D Kelleher, JV Reynolds, Vitamin C Enhances Chemosensitization of Esophageal Cancer Cells in Vitro, Journal of Chemotherapy, 17, (4), 2005, p52 - ?? Journal Article, 2005

Ryan AW, Thornton JM, Brophy K, Daly JS, McLoughlin RM, O' Morain C, Abuzakouk M, Kennedy NP, Stevens FM, Feighery C, Kelleher D, McManus R., Chromosome 5q candidate genes in coeliac disease: genetic variation at IL4, IL5, IL9, IL13, IL17B and NR3C1., Tissue Antigens, 65, (2), 2005, p150 - 155 Journal Article, 2005 DOI

Loscher, CL Leavy, O. Kelleher, D, *Mills, K.H.G and *Roche, H.M. *Equal contribution, Conjugated linoleic acid suppresses NFkB activation and IL-12 production in dendritic cells through ERK-mediated IL-10 induction., Journal of Immunology, 175, (8), 2005, p4990 - 4998 Journal Article, 2005 URL

Loscher CE, Draper E, Leavy O, Kelleher D, Mills KHG & Roche HM , Conjugated linoleic acid suppresses NF-kappa B activation and IL-12 production in dendritic cells through ERK-mediated IL-10 induction, Journal of Immunology, 175, (8), 2005, p4990 - 4998 Journal Article, 2005 TARA - Full Text URL

C Goulding, A Murphy, G MacDonald, S Barrett, J Crowe, J Hegarty, S McKiernan, D Kelleher, The CCR5-delta32 mutation: impact on disease outcome in individuals with hepatitis C infection from a single source, Gut, 54, (8), 2005, p1157 - 1161 Journal Article, 2005 DOI TARA - Full Text

Windle HJ*, Ang YS*, Athie Morales V, McManus R*, Kelleher DP , Human peripheral and gastric lymphocyte responses to Helicobacter pylori NapA and AphC differ in infected and uninfected individuals, Gut, 54, (1), 2005, p25 - 32 Journal Article, 2005 TARA - Full Text DOI

Joseph F Murphy, Frances Lennon, Christopher Steele, Dermot Kelleher, Desmond Fitzgerald, Aideen Long, Engagement of CD44 Modulates cyclooxygenase induction, VEGF generation, and cell proliferation in human vascular endothelial cells, The FASEB Journal, 19, (3), 2005, p446-448 Journal Article, 2005 TARA - Full Text DOI

Elena Papinutto, Henry J Windle, Laura Centron, Roberto Battistutta, Dermot Kelleher, Giuseppe Zanotti, Crystal structure of alkyl hydroperoxide-reductase (AhpC) from Helicobacter pylori, Biochimica et Biophysica Acta, 1, (1753(2)), 2005, p240 - 246 Journal Article, 2005

H. J. Windle, Y. S. Ang, V. A. Morales, R. McManus and D. Kelleher, Human peripheral and gastric lymphocyte responses to Helicobacter pylori NapA and AphC differ in infected and uninfected individuals, Gut, 54, (1), 2005, p25-32 Journal Article, 2005 URL

Christine E Loscher, Eve Draper, Olive Leavy, Dermot Kelleher, Kingston HG Mills, Helen M Roche, Conjugated linoleic acid suppresses NF-kappaB activation and IL-12 production in dendritic cells through ERK-Mediated IL-10 induction, The Journal of Immunology, 175, 2005, p4990 - 4998 Journal Article, 2005

Salah B., Homasany El. Din. El., Volkov Y., Takahashi M., Ono Y., Keryer G., Delouvee A., Looby E., Long A., Kelleher D., The scaffolding protein CG-NAP/AKAP450 is a critical integrating component of LFA-1 induced signaling complex in migratory T cells, The Journal of Immunology, 175, 2005, p7811 - 7818 Journal Article, 2005

M Freeley, Y Volkov, D Kelleher, A Long, Stimulus-induced phosphorylation of PKC theta at the C-terminal hydrophobic-motif in human T lymphocytes, Biochem Biophys Res Commun, 334, (2), 2005, p619 - 630 Journal Article, 2005

AW Ryan, JM Thornton, K Brophy, JS Daly, RM McLoughlin, C O'Morain, M Abuzakouk, NP Kennedy, FM Stevens, C Feighery, D Kelleher, R McManus, Chromosome 5q candidate genes in coeliac disease: genetic variation at IL4, IL5, IL9, IL13, IL17B and NR3C1, Tissue Antigens, 65, (2), 2005, p150 - 155 Journal Article, 2005

AP Nugent, HM Roche, EJ Noone, A Long, DK Kelleher, MJ Gibney, The effects of conjugated linoleic acid supplementation on immune function in healthy volunteers, European Journal of Clinical Nutrition, 59, 2005, p742 - 750 Journal Article, 2005

Murphy AM, Sheils OM, McDonald GS, Kelleher DP., Detection of a Tyrosine Phosphatase LAR on Intestinal Epithelial Cells and Intraepithelial Lymphocytes in the Human Duodenum., Mediators of Inflammation, 1, 2005, p23 - 30 Journal Article, 2005 DOI TARA - Full Text

Syed Shah, Eileen Looby, Yuri Volkov, Aideen Long, Sermot Kelleher, Ursodeoxycholic acid inhibits translocation of protein kinase C in human colonic cancer cell lines, European Journal of Cancer, 41, (14), 2005, p2160 - 2169 Journal Article, 2005

Goulding C, McManus R, Murphy A, MacDonald GS, Barrett S, Crowe J, Hegarty J, McKiernan S, Kelleher D., The CCR5-delta32 Mutation- Impact on disease outcome in individuals with hepatitis C infection from a single source, Gut, 54, (8), 2005, p1157 - 1161 Journal Article, 2005 DOI

Fanning A., Volkov Y., Freeley M., Kelleher D., Long A., CD44 cross-linking induces protein kinase C-regulated migration of human T lymphocytes, Journal of International Immunology, 17, (4), 2005, p449 - 458 Journal Article, 2005 DOI TARA - Full Text

J Cosgrave, JB Foley, R Kelly, E McGovern, K Bennett, V Young, M Tolan, P Crean, D Kelleher, MJ Walsh, Perioperative serum inflammatory response and the development of atrial fibrilation after coronary artery bypass surgery, Heart, 91, 2005, p1475 - 1476 Journal Article, 2005 DOI TARA - Full Text

JM O'Riordan, MM Abdel-Latif, N Ravi, D McNamara, PJ Byrne, G McDonald, PW Keeling, D Kelleher, JV Reynolds, Proinflammatory cytokine and nuclear factor kappa-B expression along the inflammation-metaplasia-dysplasia-adenocarcinoma sequence in the esophagus, American Journal of Gastroenterology, 100, (6), 2005, p1257 - 1264 Journal Article, 2005

Mohamed MM Abdel-Latif, Henry J Windle, Basma S El Homasany, Kamal Sabra, Dermot Kelleher, Caffeic acid phenethyl ester modulates Helicobacter pylori-induced nuclear factor-kappa B and activator protein-1 expression in gastric epithelial cells, British Journal of Pharmacology, 146, (8), 2005, p1139 - 1147 Journal Article, 2005 TARA - Full Text

B Mee, D Kelleher, J Frias, R Malone, KF Tipton, GT Henehan, HJ Windle, Characterization of cinnamyl alcohol dehydrogenase of Helicobacter pylori. An aldehyde dismutating enzyme, FEBS J, 272, (5), 2005, p1255 - 1264 Journal Article, 2005 DOI TARA - Full Text

O'Toole D, Abde;-Latif AM, Long A, Windle HJ, Murphy AM, Bowie A, O'Neill LA, Weir DG, Kelleher D, Low pH and Helicobacter pylori increase nuclear factor kappa B binding in gastric epithelial cells: a common pathway for epithelial cell injury?, Journal of Cellular Biochemistry, 96, (3), 2005, p589 - 588 Journal Article, 2005 URL DOI

D O'Toole, MM Abdel-Latif, A Long, HJ Windle, AM Murphy, A Bowie, LA O'Neill, DG Weir, D Kelleher, Low pH and Helicobacter pylori increase nuclear factor kappa B binding in gastric epithelial cells: a common pathway for epithelial cell injury?, Journal of Cellular Biochemistry, 96, (3), 2005, p589 - 598 Journal Article, 2005

M. Hennessy, S. Clarke, J. P. Spiers, D. Kelleher, F. Mulcahy, P. Hoggard, D. Back and M. Barry, Intracellular accumulation of nelfinavir and its relationship to P-glycoprotein expression and function in HIV-infected patients, Antiviral therapy, 9, (1), 2004, p115-22 Journal Article, 2004 URL

Long, A., Mitchell, S., Kashanin, D., Williams, V., Mello, A.P., Shvets, I., Kelleher, D., Volkov, Y., A Multidisciplinary Approach to the Study of T Cell Migration, Annals of the New York Academy of Sciences, 1028, 2004, p313 - 319 Journal Article, 2004 DOI URL

J Barry, M Bourke, M Buckley, B Coughlan, D Crowley, W Cullen, S Dooley, S Keating, D Kelleher, J Moloney, F Murray, PA McCormick, P MacMathuna, J O'Connor, J O'Grady, C O'Sullivan, P O'Sullivan, C Quinn, B Smyth, B Sweeney, Dublin Area Hepatitis C Initiative Group. Hepatitis C among drug users: consensus guidelines on management in general practice, Irish Journal of Medical Science, 173, (3), 2004, p145 - 150 Journal Article, 2004

A. W. Ryan, J. M. Thornton, K. Brophy, J. S. Daly, C. O'Morain, R. M. McLoughlin, N. P. Kennedy, M. Abuzakouk, F. M. Stevens, C. Feighery, D. Kelleher and R. McManus, Haplotype variation at the IBD5/SLC22A4 locus (5q31) in coeliac disease in the Irish population, Tissue antigens, 64, (2), 2004, p195-8 Journal Article, 2004 URL

S. Weldon, S. Mitchell, D. Kelleher, M. J. Gibney and H. M. Roche, Conjugated linoleic acid and atherosclerosis: no effect on molecular markers of cholesterol homeostasis in THP-1 macrophages, Atherosclerosis, 174, (2), 2004, p261-73 Journal Article, 2004 URL

Ryan AW, Thornton JM, Brophy K, Daly JS, O' Morain C, McLoughlin RM, Kennedy NP, Abuzakouk M, Stevens FM, Feighery C, Kelleher D, McManus R. , Haplotype variation at the IBD5 locus (5q31) in coeliac disease in the Irish population. , Tissue Antigens, 64, (2), 2004, p195 - 198 Journal Article, 2004 DOI

Kelleher D, Farrell R, McManus R., Pharmacogenetics of inflammatory bowel disease., Novartis Foundation Symposium - Inflammatory Bowel Disease: Crossroads of Microbes, Epithelium and Immune Systems, edited by Derek Chadwick, Jamie Goode , 263, Novartis Foundation, 2004, pp41-53 Conference Paper, 2004 DOI

Arnott IDR, Nimmo ER, Drummond HE, Fennell J, Smith BR, MacKinlay E, Morecroft J, Anderson N, O'Sullivan M, O'Morain C, Kelleher D, McManus R, Satsangi J., NOD2/CARD15, TLR4 and CD14 Mutations in Scottish and Irish Patients with Crohn's disease: Evidence for Genetic Heterogeneity within Europe., Genes and Immunity, 5, (5), 2004, p417 - 425 Journal Article, 2004 DOI

M. M. Abdel-Latif, H. J. Windle, K. A. Fitzgerald, Y. S. Ang, D. N. Eidhin, M. Li-Weber, K. Sabra and D. Kelleher, Helicobacter pylori activates the early growth response 1 protein in gastric epithelial cells, Infection and immunity, 72, (6), 2004, p3549-60 Journal Article, 2004 DOI TARA - Full Text

A. Long, S. Mitchell, D. Kashanin, V. Williams, A. Prina Mello, I. Shvets, D. Kelleher and Y. Volkov, A multidisciplinary approach to the study of T cell migration, Annals of the New York Academy of Sciences, 1028, 2004, p313-9 Journal Article, 2004 URL

S. M. McKiernan, R. Hagan, M. Curry, G. S. McDonald, A. Kelly, N. Nolan, A. Walsh, J. Hegarty, E. Lawlor and D. Kelleher, Distinct MHC class I and II alleles are associated with hepatitis C viral clearance, originating from a single source, Hepatology (Baltimore, Md), 40, (1), 2004, p108-14 Journal Article, 2004 URL

M. M. Abdel-Latif, J. O'Riordan, H. J. Windle, E. Carton, N. Ravi, D. Kelleher and J. V. Reynolds, NF-kappaB Activation in Esophageal Adenocarcinoma: Relationship to Barrett's Metaplasia, Survival, and Response to Neoadjuvant Chemoradiotherapy, Annals of Surgery, 239, (4), 2004, p491-500 Journal Article, 2004 TARA - Full Text DOI

I. D. Arnott, E. R. Nimmo, H. E. Drummond, J. Fennell, B. R. Smith, E. MacKinlay, J. Morecroft, N. Anderson, D. Kelleher, M. O'Sullivan, R. McManus and J. Satsangi, NOD2/CARD15, TLR4 and CD14 mutations in Scottish and Irish Crohn's disease patients: evidence for genetic heterogeneity within Europe?, Genes and immunity, 5, (5), 2004, p417-25 Journal Article, 2004 URL

Ryan BM, Lefort L, McManus R, Daly J, Keeling PW, Weir DG, Kelleher D, A prospective study of circulating mutant KRAS2 in the serum of patients with colorectal neoplasia: strong prognostic indicator in postoperative follow up, Gut, 52, (1), 2003, p101-108 Journal Article, 2003 DOI TARA - Full Text

A. M. Terres, H. J. Windle, E. Ardini and D. P. Kelleher, Soluble extracts from Helicobacter pylori induce dome formation in polarized intestinal epithelial monolayers in a laminin-dependent manner, Infection and immunity, 71, (7), 2003, p4067-78 Journal Article, 2003 TARA - Full Text DOI

Prina-Mello A., Volkov Y., Kelleher D., Prendergast P.J., Comparative locomotory behaviour of T Lymphocytes versus T Lymphoma cells on flat and grooved surfaces., Annals of Biomedical Engineering. , 31, 2003, p1106 - 1113 Journal Article, 2003 DOI

R. J. Farrell and D. Kelleher, Glucocorticoid resistance in inflammatory bowel disease, The Journal of Endocrinology, 178, (3), 2003, p339-46 Journal Article, 2003 URL TARA - Full Text

A. P. Mello, Y. Volkov, D. Kelleher and P. J. Prendergast, Comparative locomotory behavior of T lymphocytes versus T lymphoma cells on flat and grooved surfaces, Annals of biomedical engineering, 31, (9), 2003, p1106-13 Journal Article, 2003 URL

M. Hennessy, S. Clarke, J. P. Spiers, F. Mulcahy, D. Kelleher, E. Meadon, B. Maher, C. Bergin, S. Khoo, J. Tjia, P. Hoggard, D. Back and M. Barry, Intracellular indinavir pharmacokinetics in HIV-infected patients: comparison with plasma pharmacokinetics, Antiviral therapy, 8, (3), 2003, p191-8 Journal Article, 2003 URL

F. Khosa, J. G. McNulty, N. Hickey, P. O'Brien, A. Tobin, N. Noonan, B. Ryan, P. W. Keeling, D. P. Kelleher and G. S. McDonald, Transvenous liver biopsy via the femoral vein, Clinical radiology, 58, (6), 2003, p487-91 Journal Article, 2003 URL

McManus R, Kelleher D , Celiac disease - the villain unmasked? (Invited commentary)., New England Journal of Medicine , 348, (25), 2003, p2573-2574 Journal Article, 2003 DOI

R. McManus and D. Kelleher, Celiac disease--the villain unmasked?, The New England journal of medicine, 348, (25), 2003, p2573-4 Journal Article, 2003 URL

C. Smyth, D. Kelleher and P. W. Keeling, Hepatic manifestations of gastrointestinal diseases. Inflammatory bowel disease, celiac disease, and Whipple's disease, Clinics in liver disease, 6, (4), 2002, p1013-32 Journal Article, 2002 URL

HENNESSY, M, KELLEHER, D, SPIERS, JP, BARRY, M, KAVANAGH, P, BACK, D, MULCAHY, F, FEELY, J, ST JOHN'S WORT INCREASES EXPRESSION OF P-GLYCOPROTEIN: IMPLICATIONS FOR DRUG INTERACTIONS, BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 53, 2002, p75 - 82 Journal Article, 2002

DUFFY, M, SALEMI, M, SHEEHY, N, VANDAMME, AM, HEGARTY, J, CURRY, M, NOLAN, N, KELLEHER, D, MCKIERNAN, S, HALL, WW, COMPARATIVE RATES OF NUCLEOTIDE SEQUENCE VARIATION IN THE HYPERVARIABLE REGION OF E1/E2 AND THE NS5B REGION OF HEPATITIS C VIRUS IN PATIENTS WITH A SPECTRUM OF LIVER DISEASE RESULTING FROM A COMMON SOURCE OF INFECTION, VIROLOGY, 301, 2002, p354 - 364 Journal Article, 2002

M. Hennessy, D. Kelleher, J. P. Spiers, M. Barry, P. Kavanagh, D. Back, F. Mulcahy and J. Feely, St Johns wort increases expression of P-glycoprotein: implications for drug interactions, British Journal of Clinical Pharmacology, 53, (1), 2002, p75-82 Journal Article, 2002 TARA - Full Text DOI URL

M. Chen, E. A. O'Toole, J. Sanghavi, N. Mahmud, D. Kelleher, D. Weir, J. A. Fairley and D. T. Woodley, The epidermolysis bullosa acquisita antigen (type VII collagen) is present in human colon and patients with crohn's disease have autoantibodies to type VII collagen, The Journal of investigative dermatology, 118, (6), 2002, p1059-1064 Journal Article, 2002 DOI TARA - Full Text

M. Duffy, M. Salemi, N. Sheehy, A. M. Vandamme, J. Hegarty, M. Curry, N. Nolan, D. Kelleher, S. McKiernan and W. W. Hall, Comparative rates of nucleotide sequence variation in the hypervariable region of E1/E2 and the NS5b region of hepatitis C virus in patients with a spectrum of liver disease resulting from a common source of infection, Virology, 301, (2), 2002, p354-64 Journal Article, 2002 URL

Y. S. Ang, N. Macaleenan, N. Mahmud, P. W. Keeling, D. P. Kelleher and D. G. Weir, The yield of colonoscopy in average-risk patients with non-specific colonic symptoms, European journal of gastroenterology & hepatology, 14, (10), 2002, p1073-7 Journal Article, 2002 URL

R. J. Farrell, N. Mahmud, N. Noonan, D. Kelleher and P. W. Keeling, Diagnostic and therapeutic ERCP: a large single centre's experience, Irish journal of medical science, 170, (3), 2001, p176-80 Journal Article, 2001 URL

FARRELL, RJ, NOONAN, N, MAHMUD, N, MORRIN, MM, KELLEHER, D, KEELING, PWN, POTENTIAL IMPACT OF MAGNETIC RESONANCE CHOLANGIOPANCREATOGRAPHY ON ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY WORKLOAD AND COMPLICATION RATE IN PATIENTS REFERRED BECAUSE OF ABDOMINAL PAIN, ENDOSCOPY, 33, 2001, p668 - 675 Journal Article, 2001

FARRELL, RJ, MAHMUD, N, NOONAN, N, KELLEHER, D, KEELING, PWN, DIAGNOSTIC AND THERAPEUTIC ERCP: A LARGE SINGLE CENTRE'S EXPERIENCE, IRISH JOURNAL OF MEDICAL SCIENCE, 170, 2001, p176 - 180 Journal Article, 2001

Long A., Kelleher D., Lynch S., Volkov Y., Cutting edge: protein kinase C beta expression is critical for export of Il-2 from T cells, Journal of Immunology, 167, (2), 2001, p636-640 Journal Article, 2001 TARA - Full Text URL

Ryan BM, Molloy AM, McManus R, Arfin Q, Kelleher D, Scott JM, Weir DG. , The methylenetetrahydrofolate reductase (MTHFR) gene in colorectal cancer: Role in tumor development and significance of allelic loss in tumor progression , International Journal of Gastrointestinal Cancer , 30, (3), 2001, p105 - 111 Journal Article, 2001 DOI

R. J. Farrell, N. Noonan, N. Mahmud, M. M. Morrin, D. Kelleher and P. W. Keeling, Potential impact of magnetic resonance cholangiopancreatography on endoscopic retrograde cholangiopancreatography workload and complication rate in patients referred because of abdominal pain, Endoscopy, 33, (8), 2001, p668-75 Journal Article, 2001 URL

B. M. Ryan, A. M. Molloy, R. McManus, Q. Arfin, D. Kelleher, J. M. Scott and D. G. Weir, The methylenetetrahydrofolate reductase (MTHFR) gene in colorectal cancer: role in tumor development and significance of allelic loss in tumor progression, International journal of gastrointestinal cancer, 30, (3), 2001, p105-11 Journal Article, 2001 URL

VOLKOV, Y, LONG, A, MCGRATH, S, EIDHIN, DN, KELLEHER, D, CRUCIAL IMPORTANCE OF PKC-BETA(I) IN LFA-I-MEDIATED LOCOMOTION OF ACTIVATED T CELLS, NATURE IMMUNOLOGY, 2, 2001, p508 - 514 Journal Article, 2001

M. G. Goggins, S. A. Shah, J. Goh, A. Cherukuri, D. G. Weir, D. Kelleher and N. Mahmud, Increased urinary nitrite, a marker of nitric oxide, in active inflammatory bowel disease, Mediators of Inflammation, 10, (2), 2001, p69-73 Journal Article, 2001 TARA - Full Text URL

B. M. Ryan, R. McManus, J. S. Daly, E. Carton, P. W. Keeling, J. V. Reynolds and D. Kelleher, A common p73 polymorphism is associated with a reduced incidence of oesophageal carcinoma, British Journal of Cancer, 85, (10), 2001, p1499-1503 Journal Article, 2001 DOI

N. Mahmud, M. A. Kamm, J. L. Dupas, D. P. Jewell, C. A. O'Morain, D. G. Weir and D. Kelleher, Olsalazine is not superior to placebo in maintaining remission of inactive Crohn's colitis and ileocolitis: a double blind, parallel, randomised, multicentre study, Gut, 49, (4), 2001, p552-6 Journal Article, 2001 DOI URL TARA - Full Text

B. M. Ryan, R. McManus, J. S. Daly, E. Carton, P. W. Keeling, J. V. Reynolds and D. Kelleher, A common p73 polymorphism is associated with a reduced incidence of oesophageal carcinoma, British journal of cancer, 85, (10), 2001, p1499-503 Journal Article, 2001 TARA - Full Text URL

H. M. Roche, A. M. Terres, I. B. Black, M. J. Gibney and D. Kelleher, Fatty acids and epithelial permeability: effect of conjugated linoleic acid in Caco-2 cells, Gut, 48, (6), 2001, p797-802 Journal Article, 2001 DOI

Y. Volkov, A. Long, S. McGrath, D. Ni Eidhin and D. Kelleher, Crucial importance of PKC-beta(I) in LFA-1-mediated locomotion of activated T cells, Nature immunology, 2, (6), 2001, p508-14 Journal Article, 2001 URL

M. G. Goggins, J. Goh, M. A. O'Connell, D. G. Weir, D. Kelleher and N. Mahmud, Soluble adhesion molecules in inflammatory bowel disease, Irish journal of medical science, 170, (2), 2001, p107-11 Journal Article, 2001 URL

A. Murphy, A. Long, Y. Volkov and D. Kelleher, Cross-linking of LFA-1 induces secretion of macrophage inflammatory protein (MIP)-lalpha and MIP-1beta with consequent directed migration of activated lymphocytes, European journal of immunology, 30, (10), 2000, p3006-11 Journal Article, 2000 URL

B. M. Ryan, R. O. McManus, J. S. Daly, P. W. Keeling, D. G. Weir, F. Lefort and D. Kelleher, Serum mutant K-ras in the colorectal adenoma-to-carcinoma sequence. Implications for diagnosis, postoperative follow-up, and early detection of recurrent disease, Annals of the New York Academy of Sciences, 906, 2000, p29-30 Journal Article, 2000 URL

H. J. Windle, A. Fox, D. Ni Eidhin and D. Kelleher, The thioredoxin system of Helicobacter pylori, The Journal of biological chemistry, 275, (7), 2000, p5081-9 Journal Article, 2000 TARA - Full Text DOI

N. K. Ghaisas, J. B. Foley, D. S. O'Briain, P. Crean, D. Kelleher and M. Walsh, Adhesion molecules in nonrheumatic aortic valve disease: endothelial expression, serum levels and effects of valve replacement, Journal of the American College of Cardiology, 36, (7), 2000, p2257-62 Journal Article, 2000 URL

RYAN, BM, MCMANUS, RO, DALY, JS, KEELING, PWN, WEIR, DG, LEFORT, F, KELLEHER, D, SERUM MUTANT K-RAS IN THE COLORECTAL ADENOMA-TO-CARCINOMA SEQUENCE - IMPLICATIONS FOR DIAGNOSIS, POSTOPERATIVE FOLLOW-UP, AND EARLY DETECTION OF RECURRENT DISEASE, ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 906, 2000, p29 - 30 Journal Article, 2000

R. J. Farrell, A. Murphy, A. Long, S. Donnelly, A. Cherikuri, D. O'Toole, N. Mahmud, P. W. Keeling, D. G. Weir and D. Kelleher, High multidrug resistance (P-glycoprotein 170) expression in inflammatory bowel disease patients who fail medical therapy, Gastroenterology, 118, (2), 2000, p279-88 Journal Article, 2000 URL

Madrigal-Estebas, L., McManus, R., Byrne, B., Lynch, S., Doherty, D.G., Kelleher, D., O'Donoghue, D.P., (...), O'Farrelly, C. , Erratum: Human small intestinal epithelial cells secrete interleukin-7 and differentially express two different interleukin-7 mRNA transcripts: Implications for extrathymic T-cell differentiation (Human Immunology (1997) 58 (83)) , 2000, - 719 Miscellaneous, 2000 DOI

FARRELL, RJ, MURPHY, A, LONG, A, DONNELLY, S, CHERIKURI, A, OTOOLE, D, MAHMUD, N, KEELING, PWN, WEIR, DG, KELLEHER, D, HIGH MULTIDRUG RESISTANCE (P-GLYCOPROTEIN 170) EXPRESSION IN INFLAMMATORY BOWEL DISEASE PATIENTS WHO FAIL MEDICAL THERAPY, GASTROENTEROLOGY, 118, 2000, p279 - 288 Journal Article, 2000

S. McKiernan and D. Kelleher, Immunogenetics of hepatitis C virus, Journal of viral hepatitis, 7 Suppl 1, 2000, p13-Apr Journal Article, 2000 URL

MCMAHON, C, PILKINGTON, R, SHEA, EO, KELLEHER, D, SMITH, OP, LIVER BIOPSY IN IRISH HEPATITIS C-INFECTED PATIENTS WITH INHERITED BLEEDING DISORDERS, BRITISH JOURNAL OF HAEMATOLOGY, 109, 2000, p354 - 359 Journal Article, 2000

S. M. McKiernan, R. Hagan, M. Curry, G. S. McDonald, N. Nolan, J. Crowley, J. Hegarty, E. Lawlor and D. Kelleher, The MHC is a major determinant of viral status, but not fibrotic stage, in individuals infected with hepatitis C, Gastroenterology, 118, (6), 2000, p1124-30 Journal Article, 2000 URL

R. J. Farrell, Y. Ang, P. Kileen, D. S. O'Briain, D. Kelleher, P. W. Keeling and D. G. Weir, Increased incidence of non-Hodgkin's lymphoma in inflammatory bowel disease patients on immunosuppressive therapy but overall risk is low, Gut, 47, (4), 2000, p514-9 Journal Article, 2000 DOI

M. A. O'Sullivan, N. Mahmud, D. P. Kelleher, E. Lovett and C. A. O'Morain, Patient knowledge and educational needs in irritable bowel syndrome, European journal of gastroenterology & hepatology, 12, (1), 2000, p39-43 Journal Article, 2000 URL

B. M. Ryan and D. Kelleher, Refractory celiac disease, Gastroenterology, 119, (1), 2000, p243-51 Journal Article, 2000 URL

B. White, M. Schmidt, C. Murphy, W. Livingstone, D. O'Toole, M. Lawler, L. O'Neill, D. Kelleher, H. P. Schwarz and O. P. Smith, Activated protein C inhibits lipopolysaccharide-induced nuclear translocation of nuclear factor kappaB (NF-kappaB) and tumour necrosis factor alpha (TNF-alpha) production in the THP-1 monocytic cell line, British journal of haematology, 110, (1), 2000, p130-4 Journal Article, 2000 URL

S. Clarke, P. Harrington, C. Condon, D. Kelleher, O. P. Smith and F. Mulcahy, Late onset hepatitis and prolonged deterioration in hepatic function associated with nevirapine therapy, International journal of STD & AIDS, 11, (5), 2000, p336-7 Journal Article, 2000 URL

GHAISAS, NK, EVIDENCE OF ONGOING INFLAMMATION IN CHRONIC RHEUMATIC MITRAL VALVE DISEASE, unknown, 2000, 35, ISI Web of Science, 2000, pp527A - 527A Meeting Abstract, 2000

MURPHY, A, LONG, A, VOLKOV, Y, KELLEHER, D, CROSS-LINKING OF LFA-1 INDUCES SECRETION OF MACROPHAGE INFLAMMATORY PROTEIN (MIP)-1 ALPHA AND MIP-1 BETA WITH CONSEQUENT DIRECTED MIGRATION OF ACTIVATED LYMPHOCYTES, EUROPEAN JOURNAL OF IMMUNOLOGY, 30, 2000, p3006 - 3011 Journal Article, 2000

CLARKE, S, HARRINGTON, P, CONDON, C, KELLEHER, D, SMITH, OP, MULCAHY, F, LATE ONSET HEPATITIS AND PROLONGED DETERIORATION IN HEPATIC FUNCTION ASSOCIATED WITH NEVIRAPINE THERAPY, INTERNATIONAL JOURNAL OF STD & AIDS, 11, 2000, p336 - 337 Journal Article, 2000

WHITE, B, SCHMIDT, M, MURPHY, C, LIVINGSTONE, W, OTOOLE, D, LAWLER, M, ONEILL, L, KELLEHER, D, SCHWARZ, HP, SMITH, OP, ACTIVATED PROTEIN C INHIBITS LIPOPOLYSACCHARIDE-INDUCED NUCLEAR TRANSLOCATION OF NUCLEAR FACTOR KAPPA B (NF-KAPPA B) AND TUMOUR NECROSIS FACTOR ALPHA (TNF-ALPHA) PRODUCTION IN THE THP-1 MONOCYTIC CELL LINE, BRITISH JOURNAL OF HAEMATOLOGY, 110, 2000, p130 - 134 Journal Article, 2000

C. McMahon, R. Pilkington, E. O. Shea, D. Kelleher and O. P. Smith, Liver biopsy in Irish hepatitis C-infected patients with inherited bleeding disorders, British journal of haematology, 109, (2), 2000, p354-9 Journal Article, 2000 URL

B. White, M. Schmidt, C. Murphy, W. Livingstone, D. O'Toole, M. Lawler, L. O'Neill, D. Kelleher, H. P. Schwarz and O. P. Smith, Activated protein C inhibits lipopolysaccharide-induced nuclear translocation of nuclear factor kappaB (NF-kappaB) and tumour necrosis factor alpha (TNF-alpha) production in the THP-1 monocytic cell line, British Journal of Haematology, 110, (1), 2000, p130-134 Journal Article, 2000 URL URL DOI

RYAN, BM, KELLEHER, D, REFRACTORY CELIAC DISEASE, GASTROENTEROLOGY, 119, 2000, p243 - + Journal Article, 2000

GHAISAS, NK, FOLEY, JB, OBRIAIN, DS, CREAN, P, KELLEHER, D, WALSH, M, ADHESION MOLECULES IN NONRHEUMATIC AORTIC VALVE DISEASE: ENDOTHELIAL EXPRESSION, SERUM LEVELS AND EFFECTS OF VALVE REPLACEMENT, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 36, 2000, p2257 - 2262 Journal Article, 2000

M. Abuzakouk, C. Feighery, D. Kelleher, D. S. O'Briain, E. Jones, D. Weir, E. Casey and C. O'Farrelly, Increased HLA-DR and CD44 antigen expression in the gut: evidence of extraarticular immunological activity in rheumatoid arthritis, The Journal of rheumatology, 26, (9), 1999, p1869-76 Journal Article, 1999 URL

S. McKiernan, R. Pilkington, B. Ramsay, A. Walsh, E. Sweeney and D. Kelleher, Primary cutaneous B-cell lymphoma: an association of chronic hepatitis C infection, European journal of gastroenterology & hepatology, 11, (6), 1999, p669-72 Journal Article, 1999 URL

N. Mahmud, D. G. Weir and D. Kelleher, Systemic levels of free 5-aminosalicylic acid depend on the nature of the 5-aminosalicyclic acid derivative and not on disease activity or extent in patients with inflammatory bowel disease, Irish journal of medical science, 168, (4), 1999, p228-32 Journal Article, 1999 URL

ABUZAKOUK, M, FEIGHERY, C, KELLEHER, D, OBRIAIN, DS, JONES, E, WEIR, D, CASEY, E, OFARRELLY, C, INCREASED HLA-DR AND CD44 ANTIGEN EXPRESSION IN THE GUT: EVIDENCE OF EXTRAARTICULAR IMMUNOLOGICAL ACTIVITY IN RHEUMATOID ARTHRITIS, JOURNAL OF RHEUMATOLOGY, 26, 1999, p1869 - 1876 Journal Article, 1999

FARRELL, RJ, SMIDDY, PF, PILKINGTON, RM, TOBIN, AA, MOONEY, EE, TEMPERLEY, IJ, MCDONALD, GS, BOWMER, HA, WILSON, GF, KELLEHER, D, GUIDED VERSUS BLIND LIVER BIOPSY FOR CHRONIC HEPATITIS C: CLINICAL BENEFITS AND COSTS, JOURNAL OF HEPATOLOGY, 30, 1999, p580 - 587 Journal Article, 1999

Abuzakouk, M, Feighery, C, Kelleher, D, O'Briain, DS, Jones, E, Weir, D, Casey, E, O'Farrelly, C, Increased HLA-DR and CD44 antigen expression in the gut: evidence of extraarticular immunological activity in rheumatoid arthritis., The Journal of Rheumatology, 26, (9), 1999, p1869-76 Journal Article, 1999

R. J. Farrell, P. F. Smiddy, R. M. Pilkington, A. A. Tobin, E. E. Mooney, I. J. Temperley, G. S. McDonald, H. A. Bowmer, G. F. Wilson and D. Kelleher, Guided versus blind liver biopsy for chronic hepatitis C: clinical benefits and costs, Journal of hepatology, 30, (4), 1999, p580-7 Journal Article, 1999 URL

MCKIERNAN, S, PILKINGTON, R, RAMSAY, B, WALSH, A, SWEENEY, E, KELLEHER, D, PRIMARY CUTANEOUS B-CELL LYMPHOMA: AN ASSOCIATION OF CHRONIC HEPATITIS C INFECTION, EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 11, 1999, p669 - 672 Journal Article, 1999

Volkov Y., Long A., Kelleher D., Inside the crawling T cell: leukocyte function-associated antigen-1 cross-linking is associated with microtubule-directed translocation of protein kinase C isoenzymes beta(I) and delta, Journal of Immunology , 161, (12), 1998, p6487-95 Journal Article, 1998 URL TARA - Full Text

C. Keenan and D. Kelleher, Protein kinase C and the cytoskeleton, Cellular signalling, 10, (4), 1998, p225-32 Journal Article, 1998 URL

A. M. Terres, J. M. Pajares, D. O'Toole, S. Ahern and D. Kelleher, H pylori infection is associated with downregulation of E-cadherin, a molecule involved in epithelial cell adhesion and proliferation control, Journal of Clinical Pathology, 51, (5), 1998, p410-412 Journal Article, 1998 TARA - Full Text

DUFFY, M, LONG TERM GENETIC VARIATION OF HEPATITIS C VIRUS IN A COHORT OF PATIENTS INFECTED FROM A SINGLE SOURCE., unknown, 1998, 28, ISI Web of Science, 1998, pp683A - 683A Meeting Abstract, 1998

KEENAN, C, PROTEIN KINASE C AND THE CYTOSKELETON, by KELLEHER, D , CELLULAR SIGNALLING, 10, 1998, p225 - 232 Review, 1998

A. M. Terres, J. M. Pajares, A. M. Hopkins, A. Murphy, A. Moran, A. W. Baird and D. Kelleher, Helicobacter pylori disrupts epithelial barrier function in a process inhibited by protein kinase C activators, Infection and Immunity, 66, (6), 1998, p2943-2950 Journal Article, 1998 URL TARA - Full Text

MADRIGAL-ESTEBAS, L, MCMANUS, R, BYRNE, B, LYNCH, S, DOHERTY, DG, KELLEHER, D, ODONOGHUE, DP, FEIGHERY, C, OFARRELLY, C, HUMAN SMALL INTESTINAL EPITHELIAL CELLS SECRETE INTERLEUKIN-7 AND DIFFERENTIALLY EXPRESS TWO DIFFERENT INTERLEUKIN-7 MRNA TRANSCRIPTS: IMPLICATIONS FOR EXTRATHYMIC T-CELL DIFFERENTIATION, HUMAN IMMUNOLOGY, 58, 1998, p83 - 90 Journal Article, 1998

B. M. Ryan, G. S. McDonald, R. Pilkington and D. Kelleher, The development of hepatic granulomas following interferon-alpha2b therapy for chronic hepatitis C infection, European journal of gastroenterology & hepatology, 10, (4), 1998, p349-51 Journal Article, 1998 URL

O'Connell MA, Kelleher D, Liskamp RM, Hall N, O'Neill LA, Long A., TNF-mediated cytotoxicity of L929 cells: role of staurosporine in enhancement of cytotoxicity and translocation of protein kinase C isozymes., Cytokine, 9, (2), 1997, p83 - 92 Journal Article, 1997 URL DOI

TERRES, AM, H-PYLORI INDUCE INCREASED PERMEABILITY IN T84 EPITHELIAL MONOLAYERS, unknown, 1997, 41, ISI Web of Science, 1997, ppA23 - A23 Meeting Abstract, 1997

C. T. Taylor, A. Murphy, D. Kelleher and A. W. Baird, Changes in barrier function of a model intestinal epithelium by intraepithelial lymphocytes require new protein synthesis by epithelial cells, Gut, 40, (5), 1997, p634-640 Journal Article, 1997 TARA - Full Text

KEENAN, C, KELLEHER, D, PROTEIN KINASE C AND T CELL FUNCTION, by LONG, A , BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 1358, 1997, p113 - 126 Review, 1997

L. Madrigal-Estebas, R. McManus, B. Byrne, S. Lynch, D. G. Doherty, D. Kelleher, D. P. O'Donoghue, C. Feighery and C. O'Farrelly, Human small intestinal epithelial cells secrete interleukin-7 and differentially express two different interleukin-7 mRNA Transcripts: implications for extrathymic T-cell differentiation, Human immunology, 58, (2), 1997, p83-90 Journal Article, 1997 URL

C. Keenan, A. Long and D. Kelleher, Protein kinase C and T cell function, Biochimica et biophysica acta, 1358, (2), 1997, p113-26 Journal Article, 1997 URL

M. A. O'Connell, D. Kelleher, R. M. Liskamp, N. Hall, L. A. O'Neill and A. Long, TNF-mediated cytotoxicity of L929 cells: role of staurosporine in enhancement of cytotoxicity and translocation of protein kinase C isozymes, Cytokine, 9, (2), 1997, p83-92 Journal Article, 1997 DOI URL URL

C. Keenan, A. Long, Y. Volkov and D. Kelleher, Protein kinase C isotypes theta, delta and eta in human lymphocytes: differential responses to signalling through the T-cell receptor and phorbol esters, Immunology, 90, (4), 1997, p557-563 Journal Article, 1997 TARA - Full Text

M. A. O'Connell, D. Kelleher, R. M. Liskamp, N. Hall, L. A. O'Neill and A. Long, TNF-mediated cytotoxicity of L929 cells: role of staurosporine in enhancement of cytotoxicity and translocation of protein kinase C isozymes, Cytokine, 9, (2), 1997, p83-92 Journal Article, 1997 URL

C. Keenan, Y. Volkov, D. Kelleher and A. Long, Subcellular localization and translocation of protein kinase C isoforms zeta and epsilon in human peripheral blood lymphocytes, International Immunology, 9, (10), 1997, p1431-1439 Journal Article, 1997 TARA - Full Text

SHAHI, CN, GHAISAS, NK, GOGGINS, M, FOLEY, B, CREAN, P, KELLEHER, D, WALSH, M, ELEVATED LEVELS OF CIRCULATING SOLUBLE ADHESION MOLECULES IN PATIENTS WITH NONRHEUMATIC AORTIC STENOSIS, AMERICAN JOURNAL OF CARDIOLOGY, 79, 1997, p980 - & Journal Article, 1997

L. Madrigal-Estebas, R. McManus, B. Byrne, S. Lynch, D. G. Doherty, D. Kelleher, D. P. O'Donoghue, C. Feighery and C. O'Farrelly, Human small intestinal epithelial cells secrete interleukin-7 and differentially express two different interleukin-7 mRNA Transcripts: implications for extrathymic T-cell differentiation, Human Immunology, 58, (2), 1997, p83-90 Journal Article, 1997 DOI

BUCKLEY, M, CULHANE, A, DRUMM, B, KEANE, C, MORAN, AP, OCONNOR, HJ, COLLINS, J, KELLEHER, D, MCAVINCHEY, D, SLOAN, J, OMORAIN, C, GUIDELINES FOR THE MANAGEMENT OF HELICOBACTER PYLORI-RELATED UPPER GASTROINTESTINAL DISEASES, IRISH JOURNAL OF MEDICAL SCIENCE, 165, 1997, p2 - 11 Journal Article, 1997

H. J. Windle and D. Kelleher, Identification and characterization of a metalloprotease activity from Helicobacter pylori, Infection and Immunity, 65, (8), 1997, p3132-3137 Journal Article, 1997 TARA - Full Text

C. N. Shahi, N. K. Ghaisas, M. Goggins, B. Foley, P. Crean, D. Kelleher and M. Walsh, Elevated levels of circulating soluble adhesion molecules in patients with nonrheumatic aortic stenosis, The American journal of cardiology, 79, (7), 1997, p980-2 Journal Article, 1997 URL

R. J. Farrell, N. Noonan, I. M. Khan, M. Goggins, D. P. Kelleher and P. W. Keeling, Carcinoma of the ampulla of Vater: a tumour with a poor prognosis?, European journal of gastroenterology & hepatology, 8, (2), 1996, p139-44 Journal Article, 1996 URL

R. McManus, M. Moloney, M. Borton, A. Finch, Y. T. Chuan, E. Lawlor, D. G. Weir and D. Kelleher, Association of celiac disease with microsatellite polymorphisms close to the tumor necrosis factor genes, Human Immunology, 45, (1), 1996, p24-31 Journal Article, 1996 URL DOI

X. Fan, A. Long, M. Goggins, P. W. Keeling and D. Kelleher, Expression of CD44 and its variants on gastric epithelial cells of patients with Helicobacter pylori colonisation, Gut, 38, (4), 1996, p507-512 Journal Article, 1996 TARA - Full Text

N. Mahmud, G. S. McDonald, D. Kelleher and D. G. Weir, Microalbuminuria correlates with intestinal histopathological grading in patients with inflammatory bowel disease, Gut, 38, (1), 1996, p99-103 Journal Article, 1996

R. McManus, M. Moloney, M. Borton, A. Finch, Y. T. Chuan, E. Lawlor, D. G. Weir and D. Kelleher, Association of celiac disease with microsatellite polymorphisms close to the tumor necrosis factor genes, Human immunology, 45, (1), 1996, p24-31 Journal Article, 1996 URL

D. Wingett, A. Long, D. Kelleher and N. S. Magnuson, pim-1 proto-oncogene expression in anti-CD3-mediated T cell activation is associated with protein kinase C activation and is independent of Raf-1, Journal of immunology (Baltimore, Md, 156, (2), 1996, p549-57 Journal Article, 1996 URL

M. Goggins, A. Whelan and D. Kelleher, The immunology of coeliac disease, Annales de medecine interne, 147, (1), 1996, p40-8 Journal Article, 1996 URL

MCMANUS, R, MOLONEY, M, BORTON, M, FINCH, A, CHUAN, YT, LAWLOR, E, WEIR, DG, KELLEHER, D, ASSOCIATION OF CELIAC DISEASE WITH MICROSATELLITE POLYMORPHISMS CLOSE TO THE TUMOR NECROSIS FACTOR GENES, HUMAN IMMUNOLOGY, 45, 1996, p24 - 31 Journal Article, 1996

X. G. Fan, D. Kelleher, X. J. Fan, H. X. Xia and P. W. Keeling, Helicobacter pylori increases proliferation of gastric epithelial cells, Gut, 38, (1), 1996, p19-22 Journal Article, 1996 TARA - Full Text

R. McManus, A. G. Wilson, J. Mansfield, D. G. Weir, G. W. Duff and D. Kelleher, TNF2, a polymorphism of the tumour necrosis-alpha gene promoter, is a component of the celiac disease major histocompatibility complex haplotype, European journal of immunology, 26, (9), 1996, p2113-8 Journal Article, 1996 URL

WINGETT, D, LONG, A, KELLEHER, D, MAGNUSON, NS, PIM-1 PROTO-ONCOGENE EXPRESSION IN ANTI-CD3-MEDIATED T CELL ACTIVATION IS ASSOCIATED WITH PROTEIN KINASE C ACTIVATION AND IS INDEPENDENT OF RAF-1, JOURNAL OF IMMUNOLOGY, 156, 1996, p549 - 557 Journal Article, 1996

LANG, CC, BROWN, RM, KINIRONS, MT, DEATHRIDGE, MA, GUENGERICH, FP, KELLEHER, D, OBRIAIN, DS, GHISHAN, FK, WOOD, AJJ, DECREASED INTESTINAL CYP3A IN CELIAC DISEASE: REVERSAL AFTER SUCCESSFUL GLUTEN-FREE DIET: A POTENTIAL SOURCE OF INTERINDIVIDUAL VARIABILITY IN FIRST-PASS DRUG METABOLISM, CLINICAL PHARMACOLOGY & THERAPEUTICS, 59, 1996, p41 - 46 Journal Article, 1996

Abuzakouk, M, Kelleher, D, Feighery, C, O'Farrelly, C, Increased HLA-DR and decreased CD3 on human intestinal intraepithelial lymphocytes: evidence of activation?, Gut, 39, (3), 1996, p396-400 Journal Article, 1996 TARA - Full Text

R. McManus, A. G. Wilson, J. Mansfield, D. G. Weir, G. W. Duff and D. Kelleher, TNF2, a polymorphism of the tumour necrosis-alpha gene promoter, is a component of the celiac disease major histocompatibility complex haplotype, European Journal of Immunology, 26, (9), 1996, p2113-2118 Journal Article, 1996 URL DOI

M. Buckley, A. Culhane, B. Drumm, C. Keane, A. P. Moran, H. J. O'Connor, J. Collins, D. Kelleher, D. McAvinchey, J. Sloan and C. O'Morain, Guidelines for the management of Helicobacter pylori-related upper gastrointestinal diseases. Irish Helicobacter Pylori Study Group, Irish journal of medical science, 165 Suppl 5, 1996, p01-Nov Journal Article, 1996 URL

Maria A. O'Connell, Roisin Cleere , Aideen Long , Luke A. J. O'Neill , Dermot Kelleher , Cellular Proliferation and Activation of NFB Are Induced by Autocrine Production of Tumor Necrosis Factor in the Human T Lymphoma Line HuT 78 , Journal of Biological Chemistry, 270, (13), 1995, p7399 - 7404 Journal Article, 1995 URL

X. G. Fan, X. J. Fan, H. X. Xia, P. W. Keeling and D. Kelleher, Up-regulation of CD44 and ICAM-1 expression on gastric epithelial cells by H. pylori, APMIS, 103, (10), 1995, p744-8 Journal Article, 1995 URL

KELLEHER, D, MURPHY, A, FEIGHERY, C, CASEY, EB, LEUKOCYTE-FUNCTION-ASSOCIATED-ANTIGEN-1 (LFA-1) AND CD44 ARE SIGNALING MOLECULES FOR CYTOSKELETON-DEPENDENT MORPHOLOGICAL-CHANGES IN ACTIVATED T-CELLS, JOURNAL OF LEUKOCYTE BIOLOGY, 58, 1995, p539 - 546 Journal Article, 1995

Lynch, S, Kelleher, D, McManus, R, O'Farrelly, C, RAG1 and RAG2 expression in human intestinal epithelium: evidence of extrathymic T cell differentiation., European journal of immunology, 25, (5), 1995, p1143-7 Journal Article, 1995 DOI URL

KEENAN, C, KELLEHER, D, LONG, A, REGULATION OF NONCLASSICAL PROTEIN-KINASE-C ISOENZYMES IN A HUMAN T-CELL LINE, EUROPEAN JOURNAL OF IMMUNOLOGY, 25, 1995, p13 - 17 Journal Article, 1995

E. Corrigan, D. Kelleher, C. Feighery and A. Long, Protein kinase C isoform expression in CD45RA+ and CD45RO+ T lymphocytes, Immunology, 85, (2), 1995, p299-303 Journal Article, 1995 TARA - Full Text URL

CORRIGAN, E, KELLEHER, D, FEIGHERY, C, LONG, A, PROTEIN-KINASE-C ISOFORM EXPRESSION IN CD45RA(+) AND CD45RO(+) T-LYMPHOCYTES, IMMUNOLOGY, 85, 1995, p299 - 303 Journal Article, 1995

M. A. O'Connell, R. Cleere, A. Long, L. A. O'Neill and D. Kelleher, Cellular proliferation and activation of NF kappa B are induced by autocrine production of tumor necrosis factor alpha in the human T lymphoma line HuT 78, The Journal of Biological Chemistry, 270, (13), 1995, p7399-7404 Journal Article, 1995 TARA - Full Text DOI

MCDEVITT, J, FEIGHERY, C, OFARRELLY, C, MARTIN, G, WEIR, DG, KELLEHER, D, EFFECTS OF TUMOR-NECROSIS-FACTOR-ALPHA ON BRDU INCORPORATION IN CULTURED HUMAN ENTEROCYTES, MEDIATORS OF INFLAMMATION, 4, 1995, p31 - 37 Journal Article, 1995

LYNCH, S, KELLEHER, D, MCMANUS, R, OFARRELLY, C, RAG1 AND RAG2 EXPRESSION IN HUMAN INTESTINAL EPITHELIUM - EVIDENCE OF EXTRATHYMIC T-CELL DIFFERENTIATION, EUROPEAN JOURNAL OF IMMUNOLOGY, 25, 1995, p1143 - 1147 Journal Article, 1995

Kelleher D, Murphy A, Sheils O, Long A, McDevitt J., Tyrosine phosphorylation in the human duodenum., Gut. , 36, (1), 1995, p34-38 Journal Article, 1995 TARA - Full Text DOI

S. Lynch, D. Kelleher, R. McManus and C. O'Farrelly, RAG1 and RAG2 expression in human intestinal epithelium: evidence of extrathymic T cell differentiation, European journal of immunology, 25, (5), 1995, p1143-1147 Journal Article, 1995 URL DOI

J. McDevitt, C. Feighery, C. O'Farrelly, G. Martin, D.G. Weir, D.K. Kelleher. , Effects of tumour necrosis factor on BrdU incorporation in cultured human enterocytes., The Journal of Biological Chemistry, 4, 1995, p31-37 Journal Article, 1995 DOI TARA - Full Text

S. Lynch, D. Kelleher, R. McManus and C. O'Farrelly, RAG1 and RAG2 expression in human intestinal epithelium: evidence of extrathymic T cell differentiation, European journal of immunology, 25, (5), 1995, p1143-7 Journal Article, 1995 URL

CLEERE, R, LONG, A, KELLEHER, D, ONEILL, LAJ, AUTOCRINE REGULATION OF THE TRANSCRIPTION FACTOR NF-KAPPA-B BY TNF-ALPHA IN THE HUMAN T-CELL LYMPHOMA LINE HUT 78, BIOCHEMICAL SOCIETY TRANSACTIONS, 23, 1995, pS113 - S113 Journal Article, 1995

C. Keenan, D. Kelleher and A. Long, Regulation of non-classical protein kinase C isoenzymes in a human T cell line, European journal of immunology, 25, (1), 1995, p13-Jul Journal Article, 1995 URL

Cleere R, Long A, Kelleher D, O'Neill LA., Autocrine regulation of the transcription factor NF kappa B by TNF alpha in the human T cell lymphoma line Hut 78., Biochemical Society Transactions, 23, (1), 1995, pS113 - S113 Journal Article, 1995

KELLEHER, D, MURPHY, A, HALL, N, OMARY, MB, KEARNS, G, LONG, A, CASEY, EB, EXPRESSION OF CD44 ON RHEUMATOID SYNOVIAL-FLUID LYMPHOCYTES, ANNALS OF THE RHEUMATIC DISEASES, 54, 1995, p566 - 570 Journal Article, 1995

FAN, XJ, LONG, A, FAN, XG, KEELING, PWN, KELLEHER, D, ADHESION MOLECULE EXPRESSION ON GASTRIC INTRAEPITHELIAL LYMPHOCYTES OF PATIENTS WITH HELICOBACTER-PYLORI INFECTION, EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 7, 1995, p541 - 546 Journal Article, 1995

R. Cleere, A. Long, D. Kelleher and L. A. O'Neill, Autocrine regulation of the transcription factor NF kappa B by TNF alpha in the human T cell lymphoma line Hut 78, Biochemical Society transactions, 23, (1), 1995, p113S Journal Article, 1995 URL

X. Fan, A. Long, P. W. Keeling and D. Kelleher, Adhesion molecule expression on gastric intra-epithelial lymphocytes of patients with Helicobacter pylori infection, European journal of gastroenterology & hepatology, 7, (6), 1995, p541-6 Journal Article, 1995 URL

D. Kelleher, A. Murphy, O. Sheils, A. Long and J. McDevitt, Tyrosine phosphorylation in the human duodenum, Gut, 36, (1), 1995, p34-8 Journal Article, 1995 URL

D. Kelleher, A. Murphy, N. Hall, M. B. Omary, G. Kearns, A. Long and E. B. Casey, Expression of CD44 on rheumatoid synovial fluid lymphocytes, Annals of the Rheumatic Diseases, 54, (7), 1995, p566-570 Journal Article, 1995 TARA - Full Text

N. Mahmud, M. A. O'Connell, J. Stinson, M. G. Goggins, D. G. Weir and D. Kelleher, Tumour necrosis factor-alpha and microalbuminuria in patients with inflammatory bowel disease, European journal of gastroenterology & hepatology, 7, (3), 1995, p215-9 Journal Article, 1995 URL

OCONNELL, MA, CLEERE, R, LONG, A, ONEILL, LAJ, KELLEHER, D, CELLULAR PROLIFERATION AND ACTIVATION OF NF-KAPPA-B ARE INDUCED BY AUTOCRINE PRODUCTION OF TUMOR-NECROSIS-FACTOR-ALPHA IN THE HUMAN T-LYMPHOMA LINE HUT-78, JOURNAL OF BIOLOGICAL CHEMISTRY, 270, 1995, p7399 - 7404 Journal Article, 1995

D. Kelleher, A. Murphy, C. Feighery and E. B. Casey, Leukocyte function-associated antigen 1 (LFA-1) and CD44 are signalling molecules for cytoskeleton-dependent morphological changes in activated T cells, Journal of Leukocyte Biology, 58, (5), 1995, p539-546 Journal Article, 1995 TARA - Full Text

D. Kelleher, A. Murphy, S. Lynch and C. O'Farrelly, Adhesion molecules utilized in binding of intraepithelial lymphocytes to human enterocytes, European journal of immunology, 24, (4), 1994, p1013-6 Journal Article, 1994 URL

KELLEHER, D, MURPHY, A, LYNCH, S, OFARRELLY, C, ADHESION MOLECULES UTILIZED IN BINDING OF INTRAEPITHELIAL LYMPHOCYTES TO HUMAN ENTEROCYTES, EUROPEAN JOURNAL OF IMMUNOLOGY, 24, 1994, 1013 - 1016 Miscellaneous, 1994

Lawler M, Humphries P, O'Farrelly C, Hoey H, Sheils O, Jeffers M, O'Briain DS, Kelleher D., Adenovirus 12 E1A gene detection by polymerase chain reaction in both the normal and coeliac duodenum., Gut. , 35, (9), 1994, p1226-1232 Journal Article, 1994 TARA - Full Text DOI

N. Mahmud, J. Stinson, M. A. O'Connell, T. J. Mantle, P. W. Keeling, J. Feely, D. G. Weir and D. Kelleher, Microalbuminuria in inflammatory bowel disease, Gut, 35, (11), 1994, p1599-1604 Journal Article, 1994 TARA - Full Text DOI

FAN, XJ, CHUA, A, SHAHI, CN, MCDEVITT, J, KEELING, PWN, KELLEHER, D, GASTRIC T-LYMPHOCYTE RESPONSES TO HELICOBACTER-PYLORI IN PATIENTS WITH HELICOBACTER-PYLORI COLONIZATION, GUT, 35, 1994, p1379 - 1384 Journal Article, 1994

J. McDevitt, C. O'Farrelly, D.G. Weir, M. Bishr Omary, C. Feighery, D. Kelleher, Proliferation-associated marker in the coeliac duodenum, Eur J Gastroenterol Hepatol, 6, (3), 1994, p223-228 Journal Article, 1994 URL

LAWLER, M, HUMPHRIES, P, OFARRELLY, C, HOEY, H, SHEILS, O, JEFFERS, M, OBRIAIN, DS, KELLEHER, D, ADENOVIRUS-12 E1A GENE DETECTION BY POLYMERASE CHAIN-REACTION IN BOTH THE NORMAL AND CELIAC DUODENUM, GUT, 35, 1994, p1226 - 1232 Journal Article, 1994

M. Goggins and D. Kelleher, Celiac disease and other nutrient related injuries to the gastrointestinal tract, The American journal of gastroenterology, 89, (8 Suppl), 1994, pS2-17 Journal Article, 1994 URL

K. J. O'Byrne, M. G. Goggins, G. S. McDonald, P. A. Daly, D. P. Kelleher and D. G. Weir, A metastatic neuroendocrine anaplastic small cell tumor in a patient with multiple endocrine neoplasia type 1 syndrome. Assessment of disease status and response to doxorubicin, cyclophosphamide, etoposide chemotherapy through scintigraphic imaging with 111In-pentetreotide, Cancer, 74, (8), 1994, p2374-8 Journal Article, 1994 URL

MAHMUD, N, STINSON, J, OCONNELL, MA, MANTLE, TJ, KEELING, PWN, FEELY, J, WEIR, DG, KELLEHER, D, MICROALBUMINURIA IN INFLAMMATORY BOWEL-DISEASE, GUT, 35, 1994, p1599 - 1604 Journal Article, 1994

X. J. Fan, A. Chua, C. N. Shahi, J. McDevitt, P. W. Keeling and D. Kelleher, Gastric T lymphocyte responses to Helicobacter pylori in patients with H pylori colonisation, Gut, 35, (10), 1994, p1379-1384 Journal Article, 1994 DOI TARA - Full Text

MCDEVITT, J, OFARRELLY, C, WEIR, DG, OMARY, MB, FEIGHERY, C, KELLEHER, D, PROLIFERATION-ASSOCIATED MARKERS IN THE CELIAC DUODENUM, EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 6, 1994, p223 - 228 Journal Article, 1994

GOGGINS, M, KELLEHER, D, CELIAC-DISEASE AND OTHER NUTRIENT RELATED INJURIES TO THE GASTROINTESTINAL-TRACT, AMERICAN JOURNAL OF GASTROENTEROLOGY, 89, 1994, pS2 - S17 Journal Article, 1994

A. Long and D. Kelleher, Conventional protein kinase C isoforms are not essential for cellular proliferation of a T cell lymphoma line, FEBS letters, 333, (3), 1993, p243-7 Journal Article, 1993 URL

FAN, XJ, CHUA, A, OCONNELL, MA, KELLEHER, D, KEELING, PWN, INTERFERON-GAMMA AND TUMOR-NECROSIS-FACTOR PRODUCTION IN PATIENTS WITH HELICOBACTER-PYLORI INFECTION, IRISH JOURNAL OF MEDICAL SCIENCE, 162, 1993, p408 - 411 Journal Article, 1993

LYNCH, S, KELLEHER, D, FEIGHERY, C, WEIR, DG, OFARRELLY, C, FLOW CYTOMETRIC ANALYSIS OF INTRAEPITHELIAL LYMPHOCYTES FROM HUMAN SMALL-INTESTINAL BIOPSIES REVEALS POPULATIONS OF CD4+CD8+ AND CD8-ALPHA-ALPHA+ CELLS, EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 5, 1993, p907 - 912 Journal Article, 1993

LONG, A, KELLEHER, D, CONVENTIONAL PROTEIN-KINASE-C ISOFORMS ARE NOT ESSENTIAL FOR CELLULAR PROLIFERATION OF A T-CELL LYMPHOMA LINE, FEBS LETTERS, 333, 1993, p243 - 247 Journal Article, 1993

MURPHY, A, BREEN, KC, LONG, A, FEIGHERY, C, CASEY, EB, KELLEHER, D, NEUROFILAMENT EXPRESSION IN HUMAN T-LYMPHOCYTES, IMMUNOLOGY, 79, 1993, 167 - 170 Miscellaneous, 1993

MADRIGAL, L, LYNCH, S, FEIGHERY, C, WEIR, D, KELLEHER, D, OFARRELLY, C, FLOW CYTOMETRIC ANALYSIS OF SURFACE MAJOR HISTOCOMPATIBILITY COMPLEX CLASS-II EXPRESSION ON HUMAN EPITHELIAL-CELLS PREPARED FROM SMALL INTESTINAL BIOPSIES, JOURNAL OF IMMUNOLOGICAL METHODS, 158, 1993, p207 - 214 Journal Article, 1993

X. J. Fan, A. Chua, M. A. O'Connell, D. Kelleher and P. W. Keeling, Interferon-gamma and tumour necrosis factor production in patients with Helicobacter pylori infection, Irish journal of medical science, 162, (10), 1993, p408-11 Journal Article, 1993 URL

A. Long, M. O'Connell, R. M. Liskamp and D. Kelleher, Regulation of CD3 expression in a protein kinase C isozyme-deficient T-cell line, Immunology, 80, (4), 1993, p654-7 Journal Article, 1993 TARA - Full Text URL

A. Murphy, K. C. Breen, A. Long, C. Feighery, E. B. Casey and D. Kelleher, Neurofilament expression in human T lymphocytes, Immunology, 79, (1), 1993, p167-170 Journal Article, 1993 TARA - Full Text

LONG, A, OCONNELL, M, LISKAMP, RMJ, KELLEHER, D, REGULATION OF CD3 EXPRESSION IN A PROTEIN-KINASE-C ISOZYME-DEFICIENT T-CELL LINE, IMMUNOLOGY, 80, 1993, 654 - 657 Miscellaneous, 1993

L. Madrigal, S. Lynch, C. Feighery, D. Weir, D. Kelleher and C. O'Farrelly, Flow cytometric analysis of surface major histocompatibility complex class II expression on human epithelial cells prepared from small intestinal biopsies, Journal of immunological methods, 158, (2), 1993, p207-14 Journal Article, 1993 URL

D. Kelleher and A. Long, Development and characterization of a protein kinase C beta-isozyme-deficient T-cell line, FEBS letters, 301, (3), 1992, p310-4 Journal Article, 1992 URL

MAXWELL, WJ, KELLEHER, D, KEATING, JJ, HOGAN, FP, BLOOMFIELD, FJ, MACDONALD, GS, KEELING, PWN, ENHANCED SECRETION OF PROSTAGLANDIN-E2 BY TISSUE-FIXED MACROPHAGES IN COLONIC-CARCINOMA, DIGESTION, 47, 1991, p160 - 166 Journal Article, 1991

KELLEHER, D, MURPHY, A, CULLEN, D, LEUKOCYTE FUNCTION-ASSOCIATED ANTIGEN-1 (LFA-1) IS A SIGNALING MOLECULE FOR CYTOSKELETAL CHANGES IN A HUMAN T-CELL LINE, EUROPEAN JOURNAL OF IMMUNOLOGY, 20, 1990, 2351 - 2354 Miscellaneous, 1990

D. Kelleher, C. Feighery and D. G. Weir, Chemiluminescence by polymorphonuclear leucocyte subpopulations in chronic inflammatory bowel disease. Influence of the cell separation procedure, Digestion, 45, (3), 1990, p158-65 Journal Article, 1990 URL

D. Kelleher, A. Murphy and D. Cullen, Leukocyte function-associated antigen 1 (LFA-1) is a signaling molecule for cytoskeletal changes in a human T cell line, European journal of immunology, 20, (10), 1990, p2351-4 Journal Article, 1990 URL

W. J. Maxwell, D. Kelleher, J. J. Keating, F. P. Hogan, F. J. Bloomfield, G. S. MacDonald and P. W. Keeling, Enhanced secretion of prostaglandin E2 by tissue-fixed macrophages in colonic carcinoma, Digestion, 47, (3), 1990, p160-6 Journal Article, 1990 URL

KELLEHER, D, FEIGHERY, C, WEIR, DG, CHEMILUMINESCENCE BY POLYMORPHONUCLEAR LEUKOCYTE SUBPOPULATIONS IN CHRONIC INFLAMMATORY BOWEL-DISEASE - INFLUENCE OF THE CELL-SEPARATION PROCEDURE, DIGESTION, 45, 1990, p158 - 165 Journal Article, 1990

Kelleher, D., Defective suppression in the autologous mixed lymphocyte reaction in patients with Crohn's disease, Gut, 30, (6), 1989, p839 - 844 Journal Article, 1989 DOI TARA - Full Text

D. Kelleher, F. J. Bloomfield, T. Lenehan, M. Griffin, C. Feighery, and S. R. McCann, Chronic granulomatous disease presenting as an oculomucocutaneous syndrome mimicking Behçet's syndrome, Postgraduate Medical Journal, 62, (728), 1986, p489 - 491 Journal Article, 1986 TARA - Full Text

KELLEHER, D, JACKSON, J, WEIR, DG, FEIGHERY, C, PRIMARY BILIARY-CIRRHOSIS - AN UNDERESTIMATED DISORDER, IRISH JOURNAL OF MEDICAL SCIENCE, 155, 1986, p190 - 193 Journal Article, 1986

ORIORDAN, JW, KELLEHER, D, WILLIAMS, Y, BLOOMFIELD, FJ, EFFECT OF LITHIUM-THERAPY ON INFLAMMATORY RESPONSE, INFLAMMATION, 10, 1986, p49 - 57 Journal Article, 1986

KELLEHER, D, NEUTROPHIL LUMINESCENCE IN CHRONIC INFLAMMATORY BOWEL-DISEASE (CIBD), unknown, 1982, 23, ISI Web of Science, 1982, ppA895 - A896 Meeting Abstract, 1982

Non-Peer-Reviewed Publications

Thomas Frodl, Yolande Ferguson, Andrew Fagan, Danusia Lisiecka, Angela Carballedo, Ian Daly, James Meaney & Dermot Kelleher, Microstructural Correlates of Resilience against Major Depressive Disorder: Epigenetic Mechanisms?, 2010 Working Paper, 2010 TARA - Full Text URL

Research Expertise

Keywords

5-AMINOSALICYLIC ACID; 6-MERCAPTOPURINE; ABSORPTION; ACCUMULATION; ACTIN; ACTIN CYTOSKELETON; ACTIVATION; ACUTE BILIARY PANCREATITIS; ADENOCARCINOMA; ADHERENCE; ADHESION; ADHESION MOLECULE; ADHESION MOLECULES; ADHESION RECEPTORS; ALLELES; ALPHA-SUBUNITS; ANTI-D; ANTIGEN RECEPTOR; ANTIGENS; ANTIRETROVIRAL THERAPY; APOPTOSIS; ARACHIDONIC ACID; ASSOCIATION; AUTOIMMUNE ENTEROPATHY; AUTOMATED NEEDLE; AUTONOMIC NEUROPATHY; AZATHIOPRINE; AZODISAL SODIUM; BETA; BILE-DUCT OBSTRUCTION; BINDING; BINDING-PROTEINS; BIOCHEMISTRY; BREATH TEST; BROMODEOXYURIDINE; CAMPYLOBACTER-PYLORI; CANCER; Cancer Detection; CARDIOVASCULAR RISK-FACTORS; CD44; CD8-ALPHA HOMODIMER; CELIAC-DISEASE; CELL LYMPHOMA; CELL-ACTIVITY; CELL-ADHESION; CELLS; Cellular and molecular mechanisms regulating and resisting apoptosis; CENTRAL-NERVOUS-SYSTEM; CHEMOKINES; CHILDHOOD CELIAC-DISEASE; CHOLANGIOGRAPHY; CHOLEDOCHOLITHIASIS; CLASS-II; CLINICAL-TRIALS; COLITIS; COLON CANCER; COLONIC CARCINOMA; COMBINATION; COMMON BILE-DUCT; COMPLICATIONS; CONCENTRATE; CONTROLLED TRIAL; CROHN'S DISEASE; CROHNS-DISEASE; CROSS-LINKING; CRYOGLOBULINAEMIA; CUTANEOUS LYMPHOMA; CYCLOSPORINE METABOLISM; CYCLOSPORINE-A; CYTO-TOXICITY; CYTOCHROME-P-450; CYTOKINE SECRETION; CYTOSKELETON; CYTOTOXIC T CELL; DEPENDENT CROHNS-DISEASE; DEPENDENT DIABETES-MELLITUS; DEPENDENT PHOSPHORYLATION; DEXAMETHASONE; DIFFERENTIAL EXPRESSION; DISEASE; DIVERSITY; DNA; DNA FRAGMENTATION; DOMAIN; DOUBLE POSITIVE LYMPHOCYTES; DOUBLE-BLIND; DRUG-RESISTANCE; DRUGS; E2/NS1 REGION; EMBRYO FIBROBLASTS; ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY; ENDOTHELIUM; ENHANCEMENT; ENTEROCYTE; ENTEROCYTES; ENVELOPE PROTEIN; EPITHELIAL CELL; EPITHELIAL-CELLS; EPITHELIUM; ESCHERICHIA-COLI; EVOLUTION; EXPANSIONS; EXPRESSION; EXTRAHEPATIC TISSUES; EXTRATHYMIC DIFFERENTIATION; FACTOR TNF; FACTOR-VIII; FIBROSIS; FLOW; FLOW CYTOMETRIC ANALYSIS; FOOD INTOLERANCE; FUNCTION-ASSOCIATED ANTIGEN-1; FUNCTIONAL DYSPEPSIA; GAMMA-DELTA; GASTRIC INTRAEPITHELIAL LYMPHOCYTE; GASTRODUODENAL INJURY; GASTROINTESTINAL TISSUES; GENE; GENETIC DRIFT; Genetics of inflammatory disease; GENOME; GLUTEN-FREE DIET; GLUTEN-SENSITIVE ENTEROPATHY; GUT; HAEMOPHILIA; HEALTHY-VOLUNTEERS; HELICOBACTER PYLORI; HEMATOPOIETIC-CELLS; HEMOPHILIC PATIENTS; HEPATITIS C; HEPATITIS C VIRUS; HLA-DQ; HUMAN COLORECTAL TUMORS; HUMAN MONONUCLEAR PHAGOCYTES; HUMAN PERIPHERAL LYMPHOCYTES; HUMAN-LIVER; HUMAN-MONOCYTES; HVR1; ICAM-1; IDENTIFICATION; IFN-GAMMA; IMMUNE SELECTION; INDIVIDUALS; INDOMETHACIN; INDUCED PANCREATITIS; INFLAMMATORY-BOWEL-DISEASE; INTEGRIN; INTERFERON-ALPHA-2B; INTERLEUKIN-2; INTERMEDIATE FILAMENT PROTEINS; INTERMEDIATE FILAMENTS; INTESTINAL INTRAEPITHELIAL LYMPHOCYTES; INTRAEPITHELIAL LYMPHOCYTES; INVOLVEMENT; ISOENZYME; LEUKEMIA-CELLS; LEUKOCYTE ADHESION; LEUKOTRIENE-B4; LIPOXYGENASE; LIVER BIOPSY; LOCALIZATION; LPS; LYMPHOCYTE; LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; MACROPHAGES; MAGNETIC-RESONANCE CHOLANGIOPANCREATOGRAPHY; MALABSORPTION; MALIGNANT HISTIOCYTOSIS; MANAGEMENT; MECHANISMS; MESALAZINE; MICE; MICROALBUMINURIA; MICROTUBULE-ASSOCIATED PROTEIN-2; Molecular Immunology; MONOCLONAL-ANTIBODY; MONOCYTES; Mucosal Immunology; NECROSIS FACTOR-ALPHA; NEGATIVE DUODENAL-ULCER; NEPHROTIC SYNDROME; NF-KAPPA B; NF-KAPPA-B; NON-A; NON-B-HEPATITIS; NONSTEROIDAL ANTIINFLAMMATORY DRUGS; ODDI DYSFUNCTION; PATHOGENESIS; PATHWAYS; PEPTIC-ULCER DISEASE; PERIPHERAL-BLOOD LYMPHOCYTES; PHORBOL ESTER; PHORBOL MYRISTATE ACETATE; PHORBOL-MYRISTATE ACETATE; PHYLOGENETIC; PKC ISOTYPES; POLYMERASE CHAIN-REACTION; POLYPS; POSSIBLE REGULATORY SYSTEM; PROLIFERATIVE ACTIVITY; PROSTAGLANDIN-E2; PROTEIN; PROTEIN C; PROTEIN KINASE C; PURPURA FULMINANS; QUASISPECIES; RANDOMIZED TRIAL; RAPID UREASE TEST; RAT; RECEPTOR; RECEPTORS; RECOGNITION; RESPONSES; RIBAVIRIN; SENSITIVE ENTEROPATHY; SEPSIS; SIGNAL-TRANSDUCTION PATHWAYS; SMALL-BOWEL; SPHINCTEROTOMY; SPRUE; STENOSIS; STIMULATION; SUBUNIT; SULFASALAZINE; SUPPRESSION; T HELPER CELL; T-CELL ADHESION; T-CELL LYMPHOMAS; THERAPY; TNF-ALPHA; TRANSFERRIN RECEPTOR; TRANSPORT CONDITIONS; TUMOR NECROSIS FACTOR; ULCERATIVE JEJUNITIS; ULCERATIVE-COLITIS; Vaccinology; VARIABILITY; VARIANTS; VILLOUS ATROPHY; VIRUS-INFECTION; VON WILLEBRAND'S DISEASE

Recognition

Awards and Honours

WG Smith Prize in Pharmacology 1976

MB, BCh, BAO, BA (Hons) 1978

Arthur Ball Prize for Second Place in Surgery at Final MB Examination 1978

First Class Honours in Medicine at Final MB Examination 1978

Trinity College Travelling Scholarship in Medicine 1985

Wellcome Trust Senior Fellow in Clinical Science 1989

St Luke's Medal, Royal Academy of Medicine in Ireland 1993

Graves Medal, Royal Academy of Medicine 1994