Elisabeth Vandenberghe
Clinical Professor, Haematology
Consultant, School Office - Medicine

Publications and Further Research Outputs

Peer-Reviewed Publications

Dowling AK, Liptrot SD, O'Brien D, Vandenberghe E, Optimization and Validation of an 8-Color Single-Tube Assay for the Sensitive Detection of Minimal Residual Disease in B-Cell Chronic Lymphocytic Leukemia Detected via Flow Cytometry., 2016 Journal Article, 2016

Marchand T, Lamy T, Finel H, Arcese W, Choquet S, Finke J, Huynh A, Irrera G, Karakasis D, Konopacki J, Lambert J, Michieli M, Schouten HC, Schroyens W, Sucak G, Tischer J, Vandenberghe E, Dreger P, Hematopoietic stem cell transplantation for T-cell large granular lymphocyte leukemia: a retrospective study of the European Society for Blood and Marrow Transplantation., 2016 Journal Article, 2016

Ryan C, Ged Y, Quinn F, Walker J, Kennedy J, Gillham C, Pittaluga S, McDermott R, Vandenberghe E, Grant C, Flavin R, Classical Hodgkin Lymphoma Arising Adjacent to a Breast Implant., 2016 Journal Article, 2016

Haslam K, Langabeer SE, Hayat A, Conneally E, Vandenberghe E, Targeted next-generation sequencing of familial platelet disorder with predisposition to acute myeloid leukaemia., 2016 Journal Article, 2016

Murray C, Quinn F, Illyes G, Walker J, Castriciano G, O'Sullivan P, Grant C, Vandenberghe E, Bird B, Flavin R, Composite Blastoid Variant of Mantle Cell Lymphoma and Classical Hodgkin Lymphoma., 2016 Journal Article, 2016

O'Kane G, Bracken-Clarke D, Gardiner N, Lee G, Ni Chonghaile M, Power D, Daly PA, McCaffrey J, Bacon CL, Conneally E, Flynn C, Vandenberghe E, Kennedy MJ, Browne PV, O'Donnell DM, Hayden PJ, A single-centre analysis of 30 patients with relapsed germ cell tumours treated with the TI-CE regimen., 2016 Journal Article, 2016

Smyth L, Browne PV, Conneally E, Flynn C, Hayden P, Jeffers M, O'Brien D, Quinn F, Kelly J, Perera M, Crotty GM, Leahy M, Hennessy B, Jackson F, Ryan M, Vandenberghe E, Burkitt leukaemia/lymphoma: R-CODOX-M/R-IVAC remains gold standard treatment in BL., 2016 Journal Article, 2016

McGovern B, Quinn F, Andrews C, Jeffers M, Bacon CL, Bird B, Crotty G, Vandenberghe E, Flavin R, NOTCH1 mutation in type II Hodgkin transformation of chronic lymphocytic leukemia., 2016 Journal Article, 2016

Maguire A, Castriciano G, Walker J, Molloy K, Quinn F, Osman N, Vandenberghe E, Jeffers M, Gaffney E, Flavin R, Case Study: Diffuse Large B-Cell Lymphoma Arising in Ovarian Mature Cystic Teratoma., 2015 Journal Article, 2015

Cattaneo C, Finel H, McQuaker G, Vandenberghe E, Rossi G, Dreger P, Autologous hematopoietic stem cell transplantation for plasmablastic lymphoma: the European Society for Blood and Marrow Transplantation experience., 2015 Journal Article, 2015

Tanase A, Schmitz N, Stein H, Boumendil A, Finel H, Castagna L, Blaise D, Milpied N, Sucak G, Sureda A, Thomson K, Vandenberghe E, Vitek A, Dreger P, Lymphoma Working Party of the EBMT, Allogeneic and autologous stem cell transplantation for hepatosplenic T-cell lymphoma: a retrospective study of the EBMT Lymphoma Working Party., 2015 Journal Article, 2015

Burger JA, Tedeschi A, Barr PM, Robak T, Owen C, Ghia P, Bairey O, Hillmen P, Bartlett NL, Li J, Simpson D, Grosicki S, Devereux S, McCarthy H, Coutre S, Quach H, Gaidano G, Maslyak Z, Stevens DA, Janssens A, Ibrutinib as Initial Therapy for Patients with Chronic Lymphocytic Leukemia., 2015 Journal Article, 2015

Byrd JC, Brown JR, O'Brien S, Barrientos JC, Kay NE, Reddy NM, Coutre S, Tam CS, Mulligan SP, Jaeger U, Devereux S, Barr PM, Furman RR, Kipps TJ, Cymbalista F, Pocock C, Thornton P, Caligaris-Cappio F, Robak T, Delgado J, Ibrutinib versus ofatumumab in previously treated chronic lymphoid leukemia., 2014 Journal Article, 2014

Lyons J, Vandenberghe E, Fahy R, McDonnell C, Keane J, McLaughlin AM, An unusual lung mass post stem cell transplantation., Transplant infectious disease : an official journal of the Transplantation Society, 16, (4), 2014, p672-675 Journal Article, 2014 DOI

Liptrot S, O' Brien D, Langabeer SE, Quinn F, Mackarel AJ, Elder P, Vandenberghe E, Hayden PJ, An immunophenotypic and molecular diagnosis of composite hairy cell leukaemia and chronic lymphocytic leukaemia., 2013 Journal Article, 2013

Richardson SE, Khan I, Rawstron A, Sudak J, Edwards N, Verfuerth S, Fielding AK, Goldstone A, Kottaridis P, Morris E, Benjamin R, Peggs KS, Thomson KJ, Vandenberghe E, Mackinnon S, Chakraverty R, Risk-stratified adoptive cellular therapy following allogeneic hematopoietic stem cell transplantation for advanced chronic lymphocytic leukaemia., 2013 Journal Article, 2013

Fahy CM, Fortune A, Quinn F, McMenamin ME, Browne PV, Langabeer S, McCarron S, Hayden P, Marren P, Ni Chonghaile M, Irvine AD, Vandenberghe E, Barnes L, Development of mycosis fungoides after bone marrow transplantation for chronic myeloid leukaemia; transmission from allogeneic donor., The British journal of dermatology, 2013 Journal Article, 2013

Langabeer SE, O'Brien D, Liptrot S, Flynn CM, Hayden PJ, Conneally E, Browne PV, Vandenberghe E, Correlation of the BRAF V600E mutation in hairy cell leukaemia with morphology, cytochemistry and immunophenotype., International journal of laboratory hematology, 34, (4), 2012, p417-21 Journal Article, 2012

Langabeer SE, Quinn F, O'Brien D, McElligott AM, Kelly J, Browne PV, Vandenberghe E, Incidence of the BRAF V600E mutation in chronic lymphocytic leukaemia and prolymphocytic leukaemia., Leukemia research, 36, (4), 2012, p483-4 Journal Article, 2012

Langabeer SE, Haslam K, Kelly J, Leahy M, Vandenberghe E, Acute lymphoblastic leukaemia with an e1a3 BCR-ABL1 fusion., 2011 Journal Article, 2011

Maginn EN, Browne PV, Hayden P, Vandenberghe E, McDonagh B, Evans P, Goodyer M, Tewari P, Campiani G, Butini S, Williams DC, Zisterer DM, Lawler MP, McElligott AM., PBOX-15, a novel microtubule targeting agent, induces apoptosis, upregulates death receptors, and potentiates TRAIL-mediated apoptosis in multiple myeloma cells., British Journal of Cancer, 104, (2), 2011, p281 - 289 Journal Article, 2011 DOI

Fortune AF, Kelly K, Sargent J, O'Brien D, Quinn F, Chadwick N, Flynn C, Conneally E, Browne P, Crotty GM, Thornton P, Vandenberghe E, Large granular lymphocyte leukemia: natural history and response to treatment., Leukemia & lymphoma, 51, (5), 2010, p839-45 Journal Article, 2010

Fortune A, O'Leary H, Gilmore R, Chadwick N, Brennan L, Ní Chonghaile M, McCann SR, Browne PV, Conneally E, Vandenberghe E, T-lymphoblastic leukemia/lymphoma: a single center retrospective study of outcome., 2010 Journal Article, 2010

Haslam K, Chadwick N, Kelly J, Browne P, Vandenberghe E, Flynn C, Conneally E, Langabeer SE, Incidence and significance of FLT3-ITD and NPM1 mutations in patients with normal karyotype acute myeloid leukaemia., Irish journal of medical science, 179, (4), 2010, p507-10 Journal Article, 2010

McElligott AM, Maginn EN, Greene LM, McGuckin S, Hayat A, Browne PV, Butini S, Campiani G, Catherwood MA, Vandenberghe E, Williams DC, Zisterer DM, Lawler M, The novel tubulin-targeting agent pyrrolo-1,5-benzoxazepine-15 induces apoptosis in poor prognostic subgroups of chronic lymphocytic leukemia., 2009 Journal Article, 2009

Lawler M, McCann SR, Marsh JC, Ljungman P, Hows J, Vandenberghe E, O'Riordan J, Locasciulli A, Socié G, Kelly A, Schrezenmeier H, Marin P, Tichelli A, Passweg JR, Dickenson A, Ryan J, Bacigalupo A; Severe Aplastic Anaemia Working Party of the European Blood and Marrow Transplant Group., Serial chimerism analyses indicate that mixed haemopoietic chimerism influences the probability of graft rejection and disease recurrence following allogeneic stem cell transplantation (SCT) for severe aplastic anaemia (SAA): indication for routine assessment of chimerism post SCT for SAA., British Journal of Haematology, 144, (6), 2009, p933-945 Journal Article, 2009 DOI

Hayat A, McGuckin S, Conneally E, Brown PV, McCann SR, Lawler M, Quinn F, Delaney E, O'Rourke P, Liptrot S, O'Brien D, Vandenberghe E, Fludarabine, Cyclophosphamide and Rituximab: an effective chemoimmunotherapy combination with high remission rates for chronic lymphocytic leukaemia., Irish journal of medical science, 178, (4), 2009, p441-6 Journal Article, 2009

Zinzani PL, d'Amore F, Bombardieri E, Brammer C, Codina JG, Illidge T, Jurczak W, Linkesch W, Morschhauser F, Vandenberghe E, Van Hoof A, Consensus conference: implementing treatment recommendations on yttrium-90 immunotherapy in clinical practice - report of a European workshop., 2008 Journal Article, 2008

Hayat A., O'Brien, D., O'Rourke P., McGuckin S., Fitzgerald S., Conneally E., Browne P., McCann S., Lawler M., Vandenberghe E.., CD38 expression level and pattern of expression remains a reliable and robust marker of progressive disease in chronic lymphocytic leukemia., Leukemia & Lymphoma, 47, (11), 2006, p2371 - 2379 Journal Article, 2006

O'Donghaile D, Hayden PJ, McCarron SL, Doyle EM, Lawler M, Browne PV, Conneally E, Vandenberghe E, McCann SR., Marrow aplasia developing 13 years after HLA-identical sibling allogeneic transplantation for chronic myeloid leukaemia: successful treatment with antithymocyte globulin and peripheral blood stem cell infusion from the original donor., European Journal of Haematology, 76, (3), 2006, p258-260 Journal Article, 2006 DOI

Hayden PJ, Crampe M, Lawler M, Conneally E, McCann SR, Vandenberghe E, Browne PV., Use of DLI to achieve complete donor chimerism in a patient receiving systemic immunosuppression for refractory AIHA post-NST., Bone Marrow Transplantation, 36, 2005, p735 - 736 Journal Article, 2005

Hayden PJ, O'Driscoll A, Gardiner N, Swords R, Sargent J, Ni Ainghle F, Fortune A, Murphy PT, Leahy M, Jackson F, Ryan M, Hennessy B, Cahill M, Crotty G, Enright H, Conneally E, Vandenberghe E, McCann SR and Browne PV. , Autologous stem cell transplantation in myeloma: the St James's Hospital experience, 1997-2003., Irish Journal of Medical Science, Apr-June 174, (2), 2005, p26 - 32 Journal Article, 2005

Power M, Vandenberghe E, Browne PV, Kilmartin D, O'Connor M, Sheehy N, McCann S., Retinal and Cerebral Toxoplasmosis following Non-Myeloablative Stem Cell Transplant for Chronic Lymphocytic Leukaemia., Bone Marrow Transplantation, 36, (11), 2005, p735 - 736 Journal Article, 2005

Hayden PJ, Keogh F, Ni Conghaile M, Carroll M, Crowley M, Fitzsimon N, Gardiner N, Vandenberghe E, O'Riordan J, McCann SR, A single-centre assessment of long-term quality-of-life status after sibling allogeneic stem cell transplantation for chronic myeloid leukaemia in first chronic phase., 2004 Journal Article, 2004

Vandenberghe E, Ruiz de Elvira C, Loberiza FR, Conde E, López-Guillermo A, Gisselbrecht C, Guilhot F, Vose JM, van Biesen K, Rizzo JD, Weisenburger DD, Isaacson P, Horowitz MM, Goldstone AH, Lazarus HM, Schmitz N, Outcome of autologous transplantation for mantle cell lymphoma: a study by the European Blood and Bone Marrow Transplant and Autologous Blood and Marrow Transplant Registries., 2003 Journal Article, 2003

Allen JE, Hough RE, Goepel JR, Bottomley S, Wilson GA, Alcock HE, Baird M, Lorigan PC, Vandenberghe EA, Hancock BW, Hammond DW, Identification of novel regions of amplification and deletion within mantle cell lymphoma DNA by comparative genomic hybridization., 2002 Journal Article, 2002

Marks DI, Lush R, Cavenagh J, Milligan DW, Schey S, Parker A, Clark FJ, Hunt L, Yin J, Fuller S, Vandenberghe E, Marsh J, Littlewood T, Smith GM, Culligan D, Hunter A, Chopra R, Davies A, Towlson K, Williams CD, The toxicity and efficacy of donor lymphocyte infusions given after reduced-intensity conditioning allogeneic stem cell transplantation., 2002 Journal Article, 2002

Sokol RJ, Stamps R, Booker DJ, Scott FM, Laidlaw ST, Vandenberghe EA, Barker HF, Posttransplant immune-mediated hemolysis., 2002 Journal Article, 2002

Sampson FC, Beard SM, Scott F, Vandenberghe E, Cost-effectiveness of high-dose chemotherapy in first-line treatment of advanced multiple myeloma., 2001 Journal Article, 2001

Wilson GA, Vandenberghe EA, Pollitt RC, Rees DC, Goodeve AC, Peake IR, Reilly JT, Are aberrant BCR--ABL transcripts more common than previously thought?, 2000 Journal Article, 2000

Abu-Duhier FM, Goodeve AC, Wilson GA, Gari MA, Peake IR, Rees DC, Vandenberghe EA, Winship PR, Reilly JT, FLT3 internal tandem duplication mutations in adult acute myeloid leukaemia define a high-risk group., 2000 Journal Article, 2000

Rowe D, Cotterill SJ, Ross FM, Bunyan DJ, Vickers SJ, Bryon J, McMullan DJ, Griffiths MJ, Reilly JT, Vandenberghe EA, Wilson G, Watmore AE, Bown NP, Cytogenetically cryptic AML1-ETO and CBF beta-MYH11 gene rearrangements: incidence in 412 cases of acute myeloid leukaemia., 2000 Journal Article, 2000

Gari M, Goodeve A, Wilson G, Winship P, Langabeer S, Linch D, Vandenberghe E, Peake I, Reilly J, c-kit proto-oncogene exon 8 in-frame deletion plus insertion mutations in acute myeloid leukaemia., 1999 Journal Article, 1999

Wilson G, Frost L, Goodeve A, Vandenberghe E, Peake I, Reilly J, BCR-ABL transcript with an e19a2 (c3a2) junction in classical chronic myeloid leukemia., 1997 Journal Article, 1997

P McGettigan, EE Mooney, M Sinnott, EC Sweeney, J Feely, Sudden death in Whipple's disease, Postgraduate Medical Journal, (73), 1997, p509 - 511 Journal Article, 1997

Vandenberghe E, Pearce R, Taghipour G, Fouillard L, Goldstone AH, Role of a second transplant in the management of poor-prognosis lymphomas: a report from the European Blood and Bone Marrow Registry., 1997 Journal Article, 1997

Vandenberghe E, De Wolf-Peeters C, Vaughan Hudson G, Vaughan Hudson B, Pittaluga S, Anderson L, Linch DC, The clinical outcome of 65 cases of mantle cell lymphoma initially treated with non-intensive therapy by the British National Lymphoma Investigation Group., 1997 Journal Article, 1997

Vandenberghe EA, Goldstone AH, Autologous stem cell transplants in lymphomas., 1996 Journal Article, 1996

Vandenberghe E, Mantle cell lymphoma., 1994 Journal Article, 1994

Liesner RJ, Vandenberghe EA, Davies SC, Analgesics in sickle-cell disease., 1993 Journal Article, 1993

Vandenberghe E, Van Hove J, Brock P, Schmidt P, Delabie J, Casteels-Van Daele M, Cassiman JJ, Vanderschueren-Lodeweyckx M, Van den Berghe H, Non-endemic Burkitt's lymphoma in a patient with Bloom's syndrome., 1993 Journal Article, 1993

Criel A, Billiet J, Vandenberghe E, van den Berghe H, Louwagie A, Hidajat M, Vanhoof A, Leukaemic intermediate lymphocytic lymphomas: analysis of twelve cases diagnosed by morphology., 1992 Journal Article, 1992

Vandenberghe E, De Wolf Peeters C, Wlodarska I, Stul M, Louwagie A, Verhoef G, Thomas J, Criel A, Cassiman JJ, Mecucci C, Chromosome 11q rearrangements in B non Hodgkin's lymphoma., 1992 Journal Article, 1992

Delabie J, Vandenberghe E, Kennes C, Verhoef G, Foschini MP, Stul M, Cassiman JJ, De Wolf-Peeters C, Histiocyte-rich B-cell lymphoma. A distinct clinicopathologic entity possibly related to lymphocyte predominant Hodgkin's disease, paragranuloma subtype., 1992 Journal Article, 1992

Cuneo A, Michaux JL, Ferrant A, Van Hove L, Bosly A, Stul M, Dal Cin P, Vandenberghe E, Cassiman JJ, Negrini M, Correlation of cytogenetic patterns and clinicobiological features in adult acute myeloid leukemia expressing lymphoid markers., 1992 Journal Article, 1992

Wlodarska I, Mecucci C, Vandenberghe E, De Wolf-Peeters C, Thomas J, Hilliker C, Schoenmakers E, Stul M, Marynen P, Cassiman JJ, dup(12)(q13----qter) in two t(14;18)-negative follicular B-non-Hodgkin's lymphomas., 1992 Journal Article, 1992

Vandenberghe E, de Wolf-Peeters C, Delabie J, Thomas J, Michaux JL, Noël H, Mecucci C, Van Den Berghe H, Cytogenetic characterization of three cases of unusual B-cell non-Hodgkin's lymphoma., 1991 Journal Article, 1991

Cuneo A, Gretel Carli M, Piva N, Fagioli F, Vandenberghe E, Dal Cin P, Castoldi G, Van Den Berghe H, Clinicopathological evolution and multilineage involvement in erythroleukemia: report of a case., 1991 Journal Article, 1991

Vandenberghe E, van den Oord J, Mecucci C, Van den Berghe H, De Wolf-Peeters C, B-cell non-Hodgkin's lymphomas of follicle mantle lineage: part of a biological spectrum?, 1991 Journal Article, 1991

Vandenberghe E, Martiat P, Baens M, Stul M, Ferrant A, Cuneo A, Cassiman JJ, Mecucci C, Van den Berghe H, Megakaryoblastic leukemia with an N-ras mutation and late acquisition of a Philadelphia chromosome., 1991 Journal Article, 1991

Busschots AM, Mecucci C, Stul M, Vandenberghe E, Michaux JL, Noel H, Cassiman JJ, Van Den Berghe H, Translocation (14;19)(q32;q13.1) in a Young Patient who Developed a Large Cell Lymphoma after an Initial Diagnosis of CLL., 1991 Journal Article, 1991

Delabie J, De Wolf-Peeters C, De Vos R, Vandenberghe E, Kennes K, De Jonge I, Desmet V, True histiocytic neoplasm of Langerhans' cell type., 1991 Journal Article, 1991

Vandenberghe E, De Wolf-Peeters C, van den Oord J, Wlodarska I, Delabie J, Stul M, Thomas J, Michaux JL, Mecucci C, Cassiman JJ, Translocation (11;14): a cytogenetic anomaly associated with B-cell lymphomas of non-follicle centre cell lineage., 1991 Journal Article, 1991

Vandenberghe E, Baens M, Stul M, Bosly A, Cassiman JJ, Mecucci C, Van den Berghe H, Alteration of N-ras mutation in a patient with AML M4 and trilineage myelodysplasia., 1991 Journal Article, 1991

Vandenberghe EA, Mecucci C, Delannoy A, Van den Berghe H, Deletion of 5q by t(5;17) in therapy-related myelodysplastic syndrome., 1990 Journal Article, 1990

Kerim S, Stul M, Mecucci C, Vandenberghe E, Cuneo A, Dal Cin P, Michaux JL, Louwagie A, Cassiman JJ, Van den Berghe H, Rearrangement of immunoglobulin and TCR genes in lymphoid blast crisis of Ph+ chronic myeloid leukaemia., 1990 Journal Article, 1990

Kerim S, Mecucci C, Cuneo A, Vandenberghe E, Louwagie A, Stul M, Michaux JL, Van Den Berghe H, 5q- anomaly in lymphoid disorders., 1990 Journal Article, 1990

Vandenberghe E, Staines A, Breatnach F, O'Meara A, Recent experience with intensive combination chemotherapy for treatment of childhood acute lymphoblastic leukaemia., 1989 Journal Article, 1989

Cuneo A, Kerim S, Vandenberghe E, Van Orshoven A, Rodhain J, Bosly A, Zachee P, Louwagie A, Michaux JL, Dal Cin P, Translocation t(6;9) occurring in acute myelofibrosis, myelodysplastic syndrome, and acute nonlymphocytic leukemia suggests multipotent stem cell involvement., 1989 Journal Article, 1989

Cuneo A, Mecucci C, Kerim S, Vandenberghe E, Dal Cin P, Van Orshoven A, Rodhain J, Bosly A, Michaux JL, Martiat P, Multipotent stem cell involvement in megakaryoblastic leukemia: cytologic and cytogenetic evidence in 15 patients., 1989 Journal Article, 1989

Research Expertise

Projects

  • Title
    • Role of FISH analysis in Chronic Lymphocytic Leukaemia prognosis '
  • Summary
    • Fellowship, 2001 Principal Investigator E60, 000.00
  • Funding Agency
    • Bone Marrow for Leukaemia Trust
  • Date From
    • 2001
  • Date To
    • 2002
  • Title
    • Prognostic Factors in Chronic Lymphocytic Leukaemia
  • Summary
    • Assessing the impact of immunophenotype, cytogenetic and molecular status on the clinical behaviour of the st James Hospital c Chronic Lymphocytic Leukaemia cohort
  • Funding Agency
    • Health Research Board
  • Date From
    • 2002
  • Date To
    • 2004
  • Title
    • The clinical implications of molecular analysis of coeliac disease, refractory celiac disease and enteropathy-associated T cell lymphoma (EATCL).
  • Summary
    • Analysis of the T cell receptor clonality status in duodenal biopsies and blood correlated with morphology and immunophenotype to determine the relationship between coeliac disease, refractory coeliac disease and enteropathy associated T cell lymphoma
  • Funding Agency
    • Bone Marrow for Leukaemia Trust
  • Date From
    • 2006
  • Date To
    • 2007
  • Title
    • TP53 mutation testing in CLL in Ireland: a template for the introduction of treatment defining molecular assays
  • Summary
    • Gilead UK and Ireland Fellow ship 2016 TP53 mutation testing in CLL in Ireland: a template for the introduction of treatment defining molecular assays
  • Funding Agency
    • Gilead
  • Date From
    • November 2016
  • Date To
    • April 2017

Recognition

Memberships

American Society of Haematology 1992 – present

Member of the Lymphoma Working Party of the European Blood and Marrow Transplant (EBMT) Group 2006 – present

Chairman of the lymphoma Forum Of Ireland 2008 – present

Chairman of the haematology and lymphoma sub group of ICORG (Clinical Trials Ireland) 2006 – 2009