Tim Foster
Fellow Emeritus, Microbiology
Visiting Academic, School Office - Genetics & Microbiology

Publications and Further Research Outputs

Peer-Reviewed Publications

Heilbronner S, Monk I.R, Brozyna J.R, Heinrichs D.E, Skaar E.P, Peschel A, Foster T.J, Competing for Iron: Duplication and Amplification of the isd Locus in Staphylococcus lugdunensis HKU09-01 Provides a Competitive Advantage to Overcome Nutritional Limitation, PLoS Genetics, 12, (8), 2016, 1006246 Journal Article, 2016 URL TARA - Full Text DOI

Foster T.J, The remarkably multifunctional fibronectin binding proteins of Staphylococcus aureus, European Journal of Clinical Microbiology & Infectious Diseases, 35, 2016, p1923-1931 Journal Article, 2016 URL DOI

Herman-Bausier P, Valotteau C, Pietrocola G, Rindi S, Alsteens D, Foster T.J, Speziale P, Dufrêne Y.F, Mechanical strength and inhibition of the Staphylococcus aureus collagen-binding protein Cna, mBio, 7, (5), 2016, e01529-16 Journal Article, 2016 TARA - Full Text URL DOI

Pietrocola G, Nobile G, Gianotti V, Zapotoczna M, Foster TJ, Geoghegan JA, Speziale P, Molecular Interactions of Human Plasminogen with Fibronectin-binding Protein B (FnBPB), a Fibrinogen/Fibronectin-binding Protein from Staphylococcus aureus., The Journal of biological chemistry, 291, (35), 2016, p18148-62 Journal Article, 2016 DOI TARA - Full Text

Formosa-Dague C, Speziale P, Foster TJ, Geoghegan JA, Dufrêne YF, Zinc-dependent mechanical properties of Staphylococcus aureus biofilm-forming surface protein SasG., Proceedings of the National Academy of Sciences of the United States of America, 113, (2), 2016, p410-5 Journal Article, 2016

Brown AF, Murphy AG, Lalor SJ, Leech JM, O'Keeffe KM, Mac Aogáin M, O'Halloran DP, Lacey KA, Tavakol M, Hearnden CH, Fitzgerald-Hughes D, Humphreys H, Fennell JP, van Wamel WJ, Foster TJ, Geoghegan JA, Lavelle EC, Rogers TR, McLoughlin RM, Memory Th1 Cells Are Protective in Invasive Staphylococcus aureus Infection., PLoS pathogens, 11, (11), 2015, pe1005226 Journal Article, 2015 TARA - Full Text DOI

Monk I.R, Tree J.J, Howden B.P, Stinear T.P, Foster T.J, Complete bypass of restriction systems for major staphylococcus aureus lineages, mBio, 6, (3), 2015, p1 - 12 Journal Article, 2015 DOI URL

Herman-Bausier P, El-Kirat-Chatel S, Foster TJ, Geoghegan JA, Dufrêne YF, Staphylococcus aureus Fibronectin-Binding Protein A Mediates Cell-Cell Adhesion through Low-Affinity Homophilic Bonds., mBio, 6, (3), 2015, pe00413-15 Journal Article, 2015 TARA - Full Text

Pietrocola G, Gianotti V, Richards A, Nobile G, Geoghegan JA, Rindi S, Monk IR, Bordt AS, Foster TJ, Fitzgerald JR, Speziale P, Fibronectin Binding Proteins SpsD and SpsL Both Support Invasion of Canine Epithelial Cells by Staphylococcus pseudintermedius., Infection and immunity, 83, (10), 2015, p4093-102 Journal Article, 2015

Claro T, Kavanagh N, Foster T.J, O'Brien F.J, Kerrigan S.W, Staphylococcus epidermidis serine-aspartate repeat protein G (SdrG) binds to osteoblast integrin alpha V beta 3, Microbes and Infection, 17, (6), 2015, p395 - 401 Journal Article, 2015 URL DOI

Shambat S.M, Chen P, Hoang A.T.N, Bergsten H, Vandenesch F, Siemens N, Lina G, Monk I.R, Foster T.J, Arakere G, Svensson M, Norrby-Teglund A, Modelling staphylococcal pneumonia in a human 3D lung tissue model system delineates toxin-mediated pathology, DMM Disease Models and Mechanisms, 8, (11), 2015, p1413 - 1425 Journal Article, 2015 DOI URL

Kwiecinski J, Peetermans M, Liesenborghs L, Na M, Björnsdottir H, Zhu X, Jacobsson G, Johansson BR, Geoghegan JA, Foster TJ, Josefsson E, Bylund J, Verhamme P, Jin T, Staphylokinase Control of Staphylococcus aureus Biofilm Formation and Detachment Through Host Plasminogen Activation., The Journal of infectious diseases, 2015, p139-148 Journal Article, 2015 DOI TARA - Full Text

Farrand A.J, Haley K.P, Lareau N.M, Heilbronner S, McLean J.A, Foster T, Skaar E.P, An iron-regulated autolysin remodels the cell wall to facilitate heme acquisition in Staphylococcus lugdunensis, Infection and Immunity, 83, (9), 2015, p3578 - 3589 Journal Article, 2015 URL DOI

O'Keeffe KM, Wilk MM, Leech JM, Murphy AG, Laabei M, Monk IR, Massey RC, Lindsay JA, Foster TJ, Geoghegan JA, McLoughlin RM, Manipulation of autophagy in phagocytes facilitates Staphylococcus aureus bloodstream infection., Infection and immunity, 83, (9), 2015, p3445- Journal Article, 2015 DOI TARA - Full Text

Speziale P, Pietrocola G, Foster TJ, Geoghegan JA, Protein-based biofilm matrices in Staphylococci., Frontiers in cellular and infection microbiology, 4, 2014, p171 Journal Article, 2014 TARA - Full Text DOI

Herman P, El-Kirat-Chatel S, Beaussart A, Geoghegan JA, Foster TJ, Dufrêne YF, The binding force of the staphylococcal adhesin SdrG is remarkably strong., Molecular microbiology, 93, (2), 2014, p356-368 Journal Article, 2014 DOI

McCormack N, Foster TJ, Geoghegan JA, A short sequence within subdomain N1 of region A of the Staphylococcus aureus MSCRAMM clumping factor A is required for export and surface display., Microbiology (Reading, England), 160, (4), 2014, p659-670 Journal Article, 2014 DOI TARA - Full Text

Foster TJ, Geoghegan JA, Ganesh VK, Höök M, Adhesion, invasion and evasion: the many functions of the surface proteins of Staphylococcus aureus., Nature reviews. Microbiology, 12, (1), 2014, p49-62 Journal Article, 2014 DOI

Barbu, E.M. Mackenzie, C. Foster, T.J. Höök, M., SdrC induces staphylococcal biofilm formation through a homophilic interaction, Molecular Microbiology, 94, (1), 2014, p172 - 185 Journal Article, 2014 URL TARA - Full Text DOI

Missineo A, Di Poto A, Geoghegan JA, Rindi S, Heilbronner S, Gianotti V, Arciola CR, Foster TJ, Speziale P, Pietrocola G, IsdC from Staphylococcus lugdunensis Induces Biofilm Formation under Low-Iron Growth Conditions., Infection and immunity, 82, (6), 2014, p2448-59 Journal Article, 2014 DOI TARA - Full Text

Misstear K, McNeela EA, Murphy AG, Geoghegan JA, O'Keeffe KM, Fox J, Chan K, Heuking S, Collin N, Foster TJ, McLoughlin RM, Lavelle EC, Targeted nasal vaccination provides antibody independent protection against Staphylococcus aureus., The Journal of infectious diseases, 209, (9), 2014, p1479-1484 Journal Article, 2014 TARA - Full Text DOI

Philippe Herman, Sofiane El-Kirat-Chatel, Audrey Beaussart, Joan A. Geoghegan, Timothy J. Foster, Yves F. Dufrêne, The binding force of the staphylococcal adhesin SdrG is remarkably strong , Molecular Microbiology, 93, (2), 2014, p356-368 Journal Article, 2014 DOI

Conlon, B.P. Geoghegan, J.A. Waters, E.M. McCarthy, H. Rowe, S.E. Davies, J.R. Schaeffer, C.R. Foster, T.J. Fey, P.D. O'Gara, J.P., Role for the A domain of unprocessed accumulation-associated protein (Aap) in the attachment phase of the Staphylococcus epidermidis biofilm phenotype, Journal of Bacteriology, 196, (24), 2014, p4268 - 4275 Journal Article, 2014 DOI URL

Heilbronner, S, Hanses, F, Monk, IR, Speziale, P, Foster, TJ, Sortase A promotes virulence in experimental Staphylococcus lugdunensis endocarditis, MICROBIOLOGY-SGM, 159, 2013, p2141-2152 Journal Article, 2013 TARA - Full Text DOI

Zapotoczna, M., Jevnikar, Z., Miajlovic, H., Kos, J., Foster, T.J.., Iron-regulated surface determinant B (IsdB) promotes Staphylococcus aureus adherence to and internalization by non-phagocytic human cells, Cellular Microbiology, 15, (6), 2013, p1026-1041 Journal Article, 2013 TARA - Full Text DOI

Herman, P, El-Kirat-Chatel, S, Beaussart, A, Geoghegan, JA, Vanzieleghem, T, Foster, TJ, Hols, P, Mahillon, J, Dufrene, YF, Forces Driving the Attachment of Staphylococcus epidermidis to Fibrinogen-Coated Surfaces, LANGMUIR, 29, (42), 2013, p13018-13022 Journal Article, 2013 DOI

Hair PS, Foley CK, Krishna NK, Nyalwidhe JO, Geoghegan JA, Foster TJ, Cunnion KM, Complement regulator C4BP binds to Staphylococcus aureus surface proteins SdrE and Bbp inhibiting bacterial opsonization and killing., Results in immunology, 3, 2013, p114-21 Journal Article, 2013 DOI TARA - Full Text

Pietrocola, G, Geoghegan, JA, Rindi, S, Di Poto, A, Missineo, A, Consalvi, V, Foster, TJ, Speziale, P, Molecular Characterization of the Multiple Interactions of SpsD, a Surface Protein from Staphylococcus pseudintermedius, with Host Extracellular Matrix Proteins, PLOS ONE, 8, (6), 2013 Journal Article, 2013 DOI TARA - Full Text

Geoghegan JA, Monk IR, O'Gara JP, Foster TJ, Subdomains N2N3 of Fibronectin Binding Protein A Mediate Staphylococcus aureus Biofilm Formation and Adherence to Fibrinogen Using Distinct Mechanisms., Journal of bacteriology, 195, (11), 2013, p2675-83 Journal Article, 2013 DOI TARA - Full Text

Claro T, Widaa A, McDonnell C, Foster TJ, O'Brien FJ, Kerrigan SW, Staphylococcus aureus protein A binding to osteoblast tumour necrosis factor receptor 1 results in activation of nuclear factor kappa B and release of interleukin-6 in bone infection., Microbiology (Reading, England), 159, (Pt 1), 2013, p147-54 Journal Article, 2013 TARA - Full Text DOI

Heilbronner, S, Monk, IR, Foster, TJ, The phage integrase vector pIPI03 allows RecA -independent, site-specific labelling of Staphylococcus lugdunensis strains, PLASMID, 70, (3), 2013, p377-384 Journal Article, 2013 TARA - Full Text DOI

Monk IR, Shah IM, Xu M, Tan MW, Foster TJ., Transforming the untransformable:application of direct transformation to manipulate genetically Staphylococcus aureus and Staphylococcus epidermidis, MBio, 3, (2), 2012, pe00277- Journal Article, 2012 DOI

Mulcahy ME, Geoghegan JA, Monk IR, O'Keeffe KM, Walsh EJ, Foster TJ, McLoughlin RM, Nasal Colonisation by Staphylococcus aureus Depends upon Clumping Factor B Binding to the Squamous Epithelial Cell Envelope Protein Loricrin., PLoS Pathogens, 8, (12), 2012, pe1003092 Journal Article, 2012 TARA - Full Text DOI

Gruszka DT, Wojdyla JA, Bingham RJ, Turkenburg JP. Manfield IW, Steward A, Leech AP, Geoghegan JA, Foster TJ, Clarke J, Potts JR., Staphylococcal biofilm-forming protein has a contiguous rod-like structure , Proceedings of the National Academy of Sciences USA, 109, (17), 2012, p1011 - 1018 Journal Article, 2012 DOI

Galvin, S., Boyle, M., Russell, R.J., Coleman, D.C., Creamer, E., O'Gara, J.P., Fitzgerald-Hughes, D., Humphreys, H., Evaluation of vaporized hydrogen peroxide, Citrox and pH neutral Ecasol for decontamination of an enclosed area: A pilot study, Journal of Hospital Infection , 80, (1), 2012, 67-70 Journal Article, 2012 DOI

Smith EJ, Corrigan RM, van der Sluis T, Gründling A, Speziale P, Geoghegan JA, Foster TJ, The immune evasion protein Sbi of Staphylococcus aureus occurs both extracellularly and anchored to the cell envelope by binding lipoteichoic acid, Molecular Microbiology, 83, (4), 2012, p789 - 804 Journal Article, 2012 TARA - Full Text

Zapotoczna M, Heilbronner S, Speziale P, Foster TJ., Iron-Regulated SurfaceDeterminant (Isd) Proteins of Staphylococcus lugdunensis, Journal of Bacteriology, 194, (23), 2012, p6453 - 6467 Journal Article, 2012 TARA - Full Text DOI

Widaa A, Claro T, Foster TJ, O'Brien FJ, Kerrigan SW., Staphylococcus aureusprotein A plays a critical role in mediating bone destruction and bone loss in, PloS One, 7, (7), 2012, pArticle number e40586 Journal Article, 2012 TARA - Full Text DOI

Sharp JA, Echague CG, Hair PS, Ward MD, Nyalwidhe JO, Geoghegan JA, Foster TJ, Cunnion KM, Staphylococcus aureus surface protein SdrE binds complement regulator factor H as an immune evasion tactic., PloS one, 7, (5), 2012, pe38407 Journal Article, 2012 DOI TARA - Full Text

Monk IR, Foster TJ., Genetic manipulation of Staphylococci-breaking through the barrier, Frontiers in Cellullar and Infection Microbiology, 2:49. , (49), 2012, p1 - 9 Journal Article, 2012 DOI TARA - Full Text

Claro T, Widaa A, O'Seaghdha M, Miajlovic H, Foster TJ, O'Brien FJ, Kerrigan SW, Staphylococcus aureus Protein A Binds to Osteoblasts and Triggers Signals That Weaken Bone in Osteomyelitis., PloS one, 6, (4), 2011, pe18748 Journal Article, 2011 TARA - Full Text DOI

Vazquez, V., Liang, X., Horndahl, J.K., Ganesh, V.K., Smeds, E., Foster, T.J., Hook, M., Fibrinogen is a ligand for the Staphylococcus aureus Microbial Surface Components Recognizing Adhesive Matrix Molecules (MSCRAMM) Bone sialoprotein-binding protein (Bbp), Journal of Biological Chemistry, 286, (34), 2011, p29797-29805 Journal Article, 2011 TARA - Full Text DOI

Ganesh VK, Barbu EM, Deivanayagam CC, Le B, Anderson AS, Matsuka YV, Lin SL, Foster TJ, Narayana SV, Höök M, Structural and biochemical characterization of Staphylococcus aureus clumping factor B/ligand interactions., The Journal of biological chemistry, 286, (29), 2011, p25963-25972 Journal Article, 2011 TARA - Full Text DOI

Haley, KP, Janson, EM, Heilbronner, S, Foster, TJ, Skaar, EP, Staphylococcus lugdunensis IsdG Liberates Iron from Host Heme, JOURNAL OF BACTERIOLOGY, 193, (18), 2011, p4749-4757 Journal Article, 2011 TARA - Full Text

Heilbronner S, Holden MT, van Tonder A, Geoghegan JA, Foster TJ, Parkhill J, Bentley SD, Genome sequence of Staphylococcus lugdunensis N920143 allows identification of putative colonization and virulence factors., FEMS microbiology letters, 322, (1), 2011, p60-7 Journal Article, 2011 TARA - Full Text DOI

Miajlovic H, Fallon PG, Irvine AD, Foster TJ., Effect of filaggrin breakdown products on growth of and protein expression by Staphylococcus aureus, Journal of Allergy and Clinical Immunology, 126, (6), 2011, p1184-1190 Journal Article, 2011 TARA - Full Text DOI

Burke FM, Di Poto A, Speziale P, Foster TJ, The A domain of fibronectin-binding protein B of Staphylococcus aureus contains a novel fibronectin binding site., The FEBS journal, 278, (13), 2011, p2359-2371 Journal Article, 2011 DOI

Vazquez V, Liang X, Horndahl JK, Ganesh VK, Smeds E, Foster TJ, Hook M, Fibrinogen is a ligand for the S. aureus MSCRAMM Bbp (Bone sialoprotein-binding protein)., The Journal of Biological Chemistry, 286, (34), 2011, p29797-29810 Journal Article, 2011 TARA - Full Text DOI

Emma Jane Smith, Livia Visai, Steven W. Kerrigan, Pietro Speziale and Timothy J. Foster, The Sbi Protein Is a Multifunctional Immune Evasion Factor of Staphylococcus aureus, INFECTION AND IMMUNITY, 79, (9), 2011, p3801-3809 Journal Article, 2011 TARA - Full Text

Provenza G, Provenzano M, Visai L, Burke FM, Geoghegan JA, Stravalaci M, Gobbi M, Mazzini G, Arciola CR, Foster TJ, Speziale P, Functional analysis of a murine monoclonal antibody against the repetitive region of the fibronectin-binding adhesins fibronectin-binding protein A and fibronectin-binding protein B from Staphylococcus aureus., The FEBS journal, 277, (21), 2010, p4490-505 Journal Article, 2010 DOI TARA - Full Text

Geoghegan JA, Corrigan RM, Gruszka DT, Speziale P, O'Gara JP, Potts JR, Foster TJ, Role of surface protein SasG in biofilm formation by Staphylococcus aureus., Journal of bacteriology, 192, (21), 2010, p5663-5673 Journal Article, 2010 DOI TARA - Full Text

Kwieciński, J., Josefsson, E., Mitchell, J., Higgins, J., Magnusson, M., Foster, T., Jin, T., Bokarewa, M., Activation of plasminogen by staphylokinase reduces the severity of Staphylococcus aureus systemic infection, Journal of Infectious Diseases, 202, (7), 2010, p1041-1049 Journal Article, 2010 DOI

Hair, PS, Echague, CG, Sholl, AM, Watkins, JA, Geoghegan, JA, Foster, TJ, Cunnion, KM, Clumping factor A interaction with complement factor I increases C3b cleavage on the bacterial surface of Staphylococcus aureus, and decreases complement-mediated phagocytosis, Infection and Immunity, 78, (4), 2010, p1717 - 1727 Journal Article, 2010 TARA - Full Text

Geoghegan JA, Ganesh VK, Smeds E, Liang X, Hook M, Foster TJ, Molecular characterization of the interaction of staphylococcal microbial surface components recognizing adhesive matrix molecules (MSCRAMMS) ClfA and Fbl with fibrinogen, Journal of Biological Chemistry, 285, (9), 2010, p6208 - 6216 Journal Article, 2010 DOI TARA - Full Text

Miajlovic, H., Zapotoczna, M., Geoghegan, J.A., Kerrigan, S.W., Speziale, P., Foster, T.J., Direct interaction of iron-regulated surface determinant IsdB of Staphylococcus aureus with the GPIIb/IIIa receptor on platelets, Microbiology, 156, (3), 2010, p920-928 Journal Article, 2010 DOI TARA - Full Text

Fiona M Burke, Niamh McCormack, Simonetta Rindi, Pietro Speziale and Timothy J Foster , Fibronectin-binding protein B variation in Staphylococcus aureus, BMC Microbiology, 10, (160), 2010 Journal Article, 2010 URL TARA - Full Text DOI

Barbu, EM, Ganesh, VK, Gurusiddappa, S, MacKenzie, RC, Foster, TJ, Sudhof, TC, Hook, M, Beta-neurexin is a ligand for the Staphylococcus aureus MSCRAMM SdrC, PloS Pathogens, 6, (1), 2010, pe1000726- Journal Article, 2010 TARA - Full Text DOI

Clarke, SR, Andre, G, Walsh, EJ, Dufrene, YF, Foster, TJ, Foster, SJ, Iron-regulated surface determinant protein A mediates adhesion of Staphylococcus aureus to humancorneocyte envelope proteins, Infection and Immunity, 77, (6), 2009, p2408 - 2416 Journal Article, 2009 TARA - Full Text DOI

Corrigan, RM, Foster, TJ, An improved tetracycline-inducible expression vector for Staphylococcus aureus., Plasmid, 61, (2), 2009, p126 - 129 Journal Article, 2009 DOI

Verkaik, NJ, de Vogel, CP, Boelens, HA, Grumann, D, Hoogenboezem, T, Vink, C, Hooijkaas, H, Foster, TJ, Verbrugh, HA, van Belkum, A, van Wamel, WJ, Anti-staphylococcal humoral immune response in persistent nasal carriers and noncarriers of Staphylococcus aureus., The Journal of Infectious Diseases, 199, (5), 2009, p625 - 632 Journal Article, 2009 DOI TARA - Full Text

Geoghegan, JA, Smith, EJ, Speziale, P, Foster, TJ, Staphylococcus pseudintermedius expresses surface proteins that closely resemble those from Staphylococcus aureus, Veterinary Microbiology, 138, (3-4), 2009, p345 - 352 Journal Article, 2009 DOI

Foster, TJ, Colonization and infection of the human host by staphylococci: adhesion, survival and immune evasion., Veterinary Dermatology, 20, (5-6), 2009, p456 - 470 Journal Article, 2009 DOI

Visai, L, Yanagisawa, N, Josefsson, E, Tarkowski, A, Pezzali, I, Rooijakkers, SH, Foster, TJ, Speziale, P, Immune evasion by Staphylococcus aureus conferred by iron-regulated surface determinant protein IsdH., Microbiology , 155, (3), 2009, p667 - 679 Journal Article, 2009 TARA - Full Text DOI

Brennan, MP, Loughman, A, Devocell, M, Arasu, S, Chubb, AJ, Foster, TJ, Cox, D., Elucidating the role of Staphylococcus epidermidis serine-aspartate repeat protein G in platelet activation, Journal of Thombosis and Haemostasis, 7, (8), 2009, p1364 - 1372 Journal Article, 2009 DOI

Merino, N, Toledo-Arana, A, Vergara-Irigaray, M, Valle, J, Solano, C, Calvo, E, Lopez, JA, Foster, TJ, Penadés, JR, Lasa, I, Protein A-mediated multicellular behavior in Staphylococcus aureus., Journal of Bacteriology, 191, (3), 2009, p832 - 843 Journal Article, 2009 DOI TARA - Full Text

Hayashida, A, Bartlett, AH, Foster, TJ, Park, PW, Staphylococcus aureus beta-toxin induces lung injury through syndecan-1., The American Journal of Pathology, 174, (2), 2009, p509 - 518 Journal Article, 2009 DOI

Corrigan, RM, Miajlovic, H, Foster, TJ, Surface proteins that promote adherence of Staphylococcus aureus to human desquamated nasal epithelial cells., BMC Microbiology, 9, (1), 2009, p22- Journal Article, 2009 DOI TARA - Full Text

Loughman, A, Sweeney, T, Keane, FM, Pietrocola, G, Speziale, P, Foster, TJ, Sequence diversity in the A domain of Staphylococcus aureus fibronectin-binding protein A., BMC Microbiology, 8, (8), 2008, p74 Journal Article, 2008 DOI TARA - Full Text

Burman, JD, Leung, E, Atkins, KL, O'Seaghdha, MN, Lango, L, Bernadó, P, Bagby, S, Svergun, DI, Foster, TJ, Isenman, DE, van den Elsen, JM, Interaction of human complement with Sbi, a staphylococcal immunoglobulin-binding protein: indications of a novel mechanism of complement evasion by Staphylococcus aureus., The Journal of Biological Chemistry, 283, (25), 2008, p17579-17593 Journal Article, 2008 TARA - Full Text DOI

Walsh, E.J., Miajlovic, H., Gorkun, O., Foster, T.J. , Identification of the clumping factor B (ClfB) binding site in the Aalpha C-domain of human fibrinogen, Microbiology, 154, (2), 2008, p550 - 558 Journal Article, 2008 DOI

Kerrigan, S.W., Moore, N., Loughman, A., Meade, G., Foster, T.J., Cox, D., Molecular Basis for Staphylococcus aureus-Mediated Platelet Aggregate Formation Under Arterial Shear In Vitro, Atherosclerosis, Thrombosis and Vascular Biology, 28, (2), 2008, p335 - 340 Journal Article, 2008 DOI TARA - Full Text

Hair, PS, Ward, MD, Semmes, OJ, Foster, TJ, Cunnion, KM, Staphylococcus aureus clumping factor A binds to complement regulator factor I and increases factor I cleavage of C3b., The Journal of Infectious Diseases, 198, (1), 2008, p125 - 133 Journal Article, 2008 TARA - Full Text DOI

Walsh, EJ, Miajlovic, H, Gorkun, OV, Foster, TJ, Identification of the Staphylococcus aureus MSCRAMM clumping factor B (ClfB) binding site in the alphaC-domain of human fibrinogen., Microbiology (Reading, England), 154, (2), 2008, p550-558 Journal Article, 2008 TARA - Full Text DOI

Kubica, M., Guzik, K., Koziel, J., Zarebski, M., Richter, W., Gajkowska, B., Golda, A., Maciag-Gudowska, A., Brix, K., Shaw, L., Foster, T.J., Potempa, J. , A potential new pathway for Staphylococcus aureus dissemination: silent survival of S.aureus phagocytosed by human monocyte-derived macrophages. , PloS One, 3, 2008, pe1409- Journal Article, 2008 DOI TARA - Full Text

Josefsson, E, Higgins, J, Foster, TJ, Tarkowski, A, Fibrinogen binding sites P336 and Y338 of clumping factor A are crucial for Staphylococcus aureus virulence., PLoS ONE, 3, (5), 2008, pe2206 Journal Article, 2008 TARA - Full Text DOI

O'Neill, E, Pozzi, C, Houston, P, Humphreys, H, Robinson, DA, Loughman, A, Foster, TJ, O'Gara, JP, A novel Staphylococcus aureus biofilm phenotype mediated by the fibronectin-binding proteins, FnBPA and FnBPB., Journal of bacteriology, 190, (11), 2008, p3835-3850 Journal Article, 2008 DOI TARA - Full Text

Bartlett, AH, Foster, TJ, Hayashida, A, Park, PW, Alpha-toxin facilitates the generation of CXC chemokine gradients and stimulates neutrophil homing in Staphylococcus aureus pneumonia., The Journal of infectious diseases, 198, (10), 2008, p1529 - 1535 Journal Article, 2008 DOI TARA - Full Text

Wertheim, HF, Walsh, E, Choudhurry, R, Melles, DC, Boelens, HA, Miajlovic, H, Verbrugh, HA, Foster, T, van Belkum, A, Key role for clumping factor B in Staphylococcus aureus nasal colonization of humans., PLoS medicine, 5, (1), 2008, pe17 Journal Article, 2008 TARA - Full Text DOI

Keane, F.M., Clarke, A.A., Foster, T.J., Weiss, A.S., The N-terminal A domain of Staphylococcus aureus fibronectin binding protein A binds to tropoelastin , Biochemistry, 46, (24), 2007, p7226 - 7232 Journal Article, 2007 DOI

Risley, A., Loughman, A.A., Cywes-Bentley, C., Foster, T.J., Lee, J.C., Capsular polysaccharide masks clumping factor A-mediated adherence of Staphylococcus aureus to fibrinogen and platelets., Journal of Infectious Diseases, 196, 2007, p919 - 927 Journal Article, 2007 TARA - Full Text DOI

Tormo, A., Marti, M., Ubeda, C., Maiques, E., Cucarella, C., Valle, J. Foster, T.J., Lasa, I., Penades, J.R. , Phase-variable expression of the biofilm-associated protein (Bap) in Staphylococcus aureus, Microbiology, 153, 2007, p1702 - 1710 Journal Article, 2007 TARA - Full Text DOI

Miajlovic, H., Loughman, A.A., Cox, D., Foster, T.J. , Both complement- and fibrinogen-dependent mechanisms contribute tom platelet aggregation mediated by Staphylococcus aureus clumping factor B. , Infection and Immunity, 75, 2007, p3335 - 3343 Journal Article, 2007 TARA - Full Text DOI

Keane, F.M., Loughman, A., Valtulina, V., Brennan, M., Speziale, P., Foster, T.J. , Fibrinogen and elastin bind to the same region within the A domain of fibronectin binding protein A, an MSCRAMM of Staphylococcus aureus, Molecular Microbiology, 63, (3), 2007, p711 - 723 Journal Article, 2007 DOI

Banner, M.A., Cunniffe, J.G., Macintosh, R.L., Foster, T.J., Rohde, H., Mack, D., Hoyes, E., Derrick, J., Upton, M., Handley, P.S. , Localized tufts of fibrils on Staphylococcus epidermidis NCTC 11047 are comprised of the accumulation-associated protein, Journal of Bacteriology, 189, 2007, p2793 - 2804 Journal Article, 2007 DOI TARA - Full Text

Corrigan, R.M., Rigby, D., Handley, P.M., Foster, T.J. , The role of Staphylococcus aureus surface protein SasG in adherence and biofilm formation, Microbiology, 153, 2007, p2435 - 2446 Journal Article, 2007 TARA - Full Text

Arrecubieta, C., Lee, M.H., Macey, A., Foster, T.J., Lowy, F.D. , SdrF, a Staphylococcus aureus surface protein, binds type I collagen, Journal of Biological Chemistry, 282, 2007, p18767 - 18776 Journal Article, 2007 DOI TARA - Full Text

Fitzgerald, J.R., Loughman, A., Keane, F., Brennan, M., Knobel, M., Higgins, J., Visai, L., Speziale, P., Cox, D. and Foster, T.J. , Fibronectin-binding proteins of Staphylococcus aureus mediate activation of human platelets via fibrinogen and fibronectin bridges to integrin GPIIb/IIIa and IgG binding to the FCgammaRIIa receptor., Molecular Microbiology, 59, (1), 2006, p212 - 230 Journal Article, 2006 DOI

Gomez, M.I., O Seaghdha, M., Margaree, M., Foster, T.J., and Prince, A. , Staphylococcus aureus protein A activates TNFR-1 signalling through conserved IgG binding domains., Journal of Biological Chemistry, 281, 2006, p33190 - 33196 Journal Article, 2006 DOI

Rindi, S., Cicalini, S., Pietrocola, G., Venditti, M., Festa, A., Foster, T.J., Petrosillo, N. Speziale, P., Antibody response in patients with endocarditis caused by Staphylococcus aureus, European Journal of Clinical Investigation, 36, (8), 2006, p536 - 543 Journal Article, 2006 DOI

Fitzgerald, J.R., Foster, T.J. and Cox D., The interaction of bacterial pathogens with platelets, Nature Reviews Microbiology, 4, 2006, p445 - 457 Journal Article, 2006 DOI

O Seaghdha, M., van Schooten, C.J., Kerrigan, S.W., Emsley, J., Silverman, G.J., Cox, D., Lenting, P.J., and Foster, T.J., Staphylococcus aureus protein A binding to von Willebrand factor A1 domain is mediated by conserved IgG binding regions, FEBS Journal, 273, (21), 2006, p4831 - 4841 Journal Article, 2006 DOI

Arrecubieta, C., Asai, T., Bayern, M., Loughman, A., Fitzgerald, J.R., Shelton, C.E., Baron, H.M., Dang, N.C., Deng, M.C., Naka, Y., Foster, T.J., and Lowy, F.D. , The role of Staphylococcus aureus adhesins in the pathogenesis of ventricular assist device-related infections, Journal of Infectious Diseases, 193, (8), 2006, p1109 - 1119 Journal Article, 2006 DOI

Higgins, J., Loughman, A., van Kessel, K.P.M., van Strijp, J.A.G. and Foster, T.J. , Clumping factor A of Staphylococcus aureus inhibits phagocytosis by human polymorphonuclear leucocytes, FEMS Microbiology Letters, 258, (2), 2006, p290 - 296 Journal Article, 2006 DOI

Schaffer, A.C., Solinga, R.M., Cocchiaro, J., Portoles, M., Kiser, K., Risley, A., Randall, S.M., Valtulina, V., Speziale, P., Walsh, E., Foster, T., and Lee, J.C. , Immunization with Staphylococcus aureus clumping factor B, a major determinant in nasal carriage, reduces nasal colonization in a murine model., Infection and Immunity, 74, (4), 2006, p2145 - 2153 Journal Article, 2006 DOI

Loughman, A., Fitzgerald, J.R., Brennan, M.P., Higgins, J., Downer, R., Cox, D., and Foster T.J. , Roles for fibrinogen, immunoglobulin and complement in platelet activation promoted by Staphylococcus aureus clumping factor A., Molecular Microbiology, 57, (3), 2005, p804 - 818 Journal Article, 2005 DOI

Palmqvist, N., Foster, T., Fitzgerald, R., Josefsson, E., and Tarkowski, A. (2005). , Fibronectin-binding proteins and fibrinogen-binding clumping factors play distinct roles in staphylococcal arthritis and systemic inflammation, Journal of Infectious Diseases, 191, (5), 2005, p791 - 798 Journal Article, 2005 DOI

Foster, T.J. , Immune evasion by staphylococci, Nature Reviews Microbiology, 3, (12), 2005, p948 - 958 Journal Article, 2005 DOI

Walsh, E.J., O'Brien, L.M., Liang, X., Hook, M., and Foster, T.J., Clumping factor B, a fibrinogen-binding MSCRAMM of staphylococcus aureus, also binds to the tail region of type I cytokeratin 10, Journal of Biological Chemistry, 279, (49), 2004, p50691 - 50699 Journal Article, 2004 DOI

Olesky, A., Golonka, E., Banbula, A., Szmyd, G., Moon, J., Kubica, M., Greenbaum, D., Boygo, M., Foster, T.J., Travis J. and Potempa, J., Growth phase-dependent production of a cell wall-associated elastinolytic cysteine proteinase by Staphylococcus epidermidis, Biological Chemistry, 385, (6), 2004, p525 - 535 Journal Article, 2004 DOI

Holden, D., Feil, E.J., Lindsay, J.A., Peacock, S.J., Day, N.P., Enright, M.C., Foster, T.J., Moore, C.E., Hurst, L., Atkin, R., Barron, A., Bason, N., Bentley, S.D., Chillingworth, T., Churcher, A., Clark, L., Corton, C., Cronin, A., Doggett, J., Dowd, L., Feltwell, T., Hance, Z., Harris, B., Hauser, H., Holropyd, S., Jagels, K., James, K.D., Lennard, N., Line, A., Mayes, R., Moule, S., Mungall, K., Ormond, D., Quail, M.A., Rabbinowitsch, E., Rutherford, K., Sanders, M., Sharp, S., Simmopnds, M., Stevens, K., Whitehead, S., Barrell, B.G., Spratt, B.G., and Parkhill, J., Complete genomes of two clinical Staphylococcus aureus strains: evidence for the rapid evolution of virulence and drug resistance, Proceedings of the National Academy of Sciences of the United States of America, 101, (26), 2004, p9786 - 9791 Journal Article, 2004 DOI

Foster, T.J., Nasal colonization by Staphylococcus aureus, Nature Medicine, 10, 2004, p447 - 447 Journal Article, 2004 DOI

Jin, T., Bakarewa, M., Foster, T., Mitchell, J., Higgins, J. and Tarkowski, A., Staphylococcus aureus resists human defensins by production of staphylokinase, a novel bacterial evasion mechanism., Journal of Immunology, 172, 2004, pp.1169 - 1176 Journal Article, 2004 URL

Roche, F.M., Downer, R., Keane, F., Speziale, P., Park, P.W., and Foster T.J., The N-terminal A domain of fibronectin-binding proteins A and B promotes adhesion of Staphylococcus aureus to elastin. , Journal of Biological Chemistry, 279, (37), 2004, p38433 - 38440 Journal Article, 2004 DOI

Mitchell, J., Tristan, A., and Foster, T.J. , Characterization of the fibrinogen-binding surface protein Fbl of Staphylococcus lugdunensis., Microbiology, 150, 2004, p3831 - 3841 Journal Article, 2004 DOI

Foster, T.J., The Staphylococcus aureus "superbug", Journal of Clinical Investigation, 114, (12), 2004, p1693 - 1696 Journal Article, 2004 TARA - Full Text DOI

Pietricola, G., Schubert, A., Visai, L., Torti, M., Fitzgerald, J.R., Foster, T.J., Reinscheid, D.J., and Speziale, P. , FbsA, a fibrinogen-binding protein from Streptococcus agalactiae, mediates platelet aggregation, Blood, 105, (3), 2004, p1052 - 1059 Journal Article, 2004 DOI

McAleese, F.M. and Foster, T.J., Analysis of mutations in the Staphylococcus aureus clfB promoter leading to increased expression., Microbiology, 149, (1), 2003, p99 - 109 Journal Article, 2003 DOI

Roche, F.M., Meehan, M., and Foster, T.J., The Staphylococcus ayreus surface protein SasG and its homologues promote bacterial adherence to human desquamated nasal epithelial cells, Microbiology, 149, 2003, p2759 - 2767 Journal Article, 2003 DOI

Said-Salim, B., Dunman, P.M., McAleese, F.M., Macapagal, D., Murphy, E., McNamara, P.J., Arvidson, S., Foster, T.J., Projan, S.J. and Kreiswirth, B.N., Global regulation of Staphylococcus aureus genes by Rot., Journal of Bacteriology, 185, (2), 2003, p610 - 619. Journal Article, 2003 DOI

Park, P.W., Foster, T.J., Nishi, E., Duncan, S.J., Klagsbrun, M. and Chen, Y., Activation of syndecan-1 ectodomain shedding by Staphylococcus aureus alpha-toxin and beta-toxin., Journal of Biological Chemistry, 279, (1), 2003, p251 - 258 Journal Article, 2003 DOI

Roche, F.M., Massey, R., Peacock, S.J., Day, N.P., Visai, L., Speziale, P., Lam, A., Pallen, M. and Foster, T.J., Characterization of novel LPXTG-containing proteins of Staphylococcus aureus identified from genome sequences., Microbiology, 149, 2003, p643 - 654 Journal Article, 2003 DOI

Ubeda, C., Tormo, M.A., Cucarella, C., Trotonda, P., Foster, T.J., Lasa, I. and Penades, J.R., Sip, an integrase protein with excision, circularization and integration activities, defines a new family of mobile Staphylococcus aureus pathogenicity islands, Molecular Microbiology, 49, (1), 2003, p193 - 210 Journal Article, 2003 DOI

Surface protein adhesins of staphylococci in, editor(s)M.Wilson (ed.) , Bacterial adhesion to host tissues: mechanisms and consequences, Cambridge, Cambridge University Press, 2002, pp.3 - 26, [Foster, T.J.] Book Chapter, 2002

McElroy, M.C., Cain, D.J., Tyrell, C., Foster, T.J., and Haslett, C. , Increased virulence of a fibronectin-binding protein mutant of Staphylococcus aureus in a rat model of pneumonia, Infection and Immunity, 70, (7), 2002, p3865 - 3873 Journal Article, 2002 DOI

O'Brien, L.M., Walsh, E.J., Massey, R.C., Peacock, S.J. and Foster, T.J., Staphylococcus aureus clumping factor B (ClfB) promotes adherence to human type I cytokeratin 10: Implications for nasal colonization , Cellular Microbiology, 4, (11), 2002, p759 - 770 Journal Article, 2002 DOI

Downer, R., Roche, F., Park, P.W., Mecham, R.P., and Foster, T.J. , The elastin binding protein of Staphylococcus aureus (EbpS) is expressed at the cell surface as an integral membrane protein and not as a cell wall-associated protein., Journal of Biological Chemistry, 277, 2002, p243 - 250 Journal Article, 2002 DOI

Palmqvist, N., Foster, T., Tarowski, A. and Josefsson, E., Protein A is a virulence factor in Staphylococcus aureus arthritis and septic death, Microbial Pathogenesis, 33, (5), 2002, p239 - 249. Journal Article, 2002 DOI

Cucurella, C., Tormo, M.A., Knecht, E., Amorena, B., Lasa, I., Foster, T.J. Penade, J., Expression of biofilm-associated protein interferes with host protein receptors of Staphylococcus aureus and alters the infective process. , Infection and Immunity, 70, (6), 2002, p3180 - 3186 Journal Article, 2002 DOI

Cucurella, C., Tormo, M.A., Knecht, E., Amorena, B., Lasa, I., Foster, T.J. Penades, J., Expression of biofilm-associated protein interferes with host protein receptors of Staphylococcus aureus and alters the infective process. , Infection and Immunity, 70, (6), 2002, p3180 - 3186 Journal Article, 2002 DOI

O'Brien, L.M., Kerrigan, S.W., Kaw, G., Hogan, M., Penedes, J., Litt, D., Fitzgerald, D.J., Foster, T.J. and Cox, D. , Multiple mechanisms for the activation of human platelet aggregation by Staphylococcus aureus: roles for the clumping factors CfA and ClfB, the serine-aspartate repeat protein SdrE and protein A, Molecular Microbiology, 44, (4), 2002, p1033 - 1044 Journal Article, 2002 DOI

Djacs, J.J., Austin, M.S., Sloop, G.D., Moreau, J.M., Hume, E.B., Thompson, H.W., McAleese, F.M., Foster, T.J., O'Callaghan, R.J.., Corneal pathogenesis of Staphylococcus aureus strain Newman. , Investigative Ophthalmology and Visual Science, 43, (4), 2002, p1109 - 1115 Journal Article, 2002 URL

Massey, R.C., Dissanayeke, S.R.,Cameron, B., Ferguson, D., Foster, T.J. and Peacock, S.J., Functional blocking of Staphylococcus aureus adhesins following growth in ex vivo media, Infection and Immunity, 70, (10), 2002, p5339 - 5345 Journal Article, 2002 DOI

Staphylococcus aureus in, editor(s)M.Sussman (ed.) , Molecular Medical Microbiology, San Diego; California; London, Academic Press, 2002, pp.839 - 888, [Foster, T.J.] Book Chapter, 2002

McAleese, F.M., Walsh, E.J., Sieprawska, M., Potempa, J. Foster, T.J. , Loss of clumping factor B fibrinogen binding activity by Staphylococcus aureus involves cessation of transcription, shedding and cleavage by metalloprotease, Journal of Biological Chemistry, 276, (32), 2001, p29969 - 29978 Journal Article, 2001 DOI

Perkins, S., Walsh, E.J., Deivanayagam, C.C.S., Narayana, S.V.L., Foster, T.J., and Hook, M. , Structural organization of the fibrinogen-binding region of the clumping factor B MSCRAMM of Staphylococcus aureus., Journal of Biological Chemistry, 276, (48), 2001, p44721 - 44728 Journal Article, 2001 DOI

Savolainen, K., Paulin, L., Westerlund-Wikstrom, B., Foster, T.J., Korhonen, T.K., Kuusela, P., Expression of pls, a gene closely associated with the mecA gene of methicillin-resistant Staphylococcus aureus prevents bacterial adhesion in vitro., Infection and Immunity, 69, (5), 2001, p3013 - 3020 Journal Article, 2001 DOI

Fitzgerald, J.R., Monday, S.R., Foster, T.J., Bohach, G.A., Hartigan, P.J., Meaney, W.J., Smyth, C.J., Characterization of a putative pathogenicity island from bovine Staphylococcus aureus encoding multiple superantigens, Journal of Bacteriology, 183, (1), 2001, p63 - 70 Journal Article, 2001 DOI

Hartford OM, Wann ER, Höök M, Foster TJ., Identification of residues in the Staphylococcus aureus fibrinogen-binding MSCRAMM clumping factor A (ClfA) that are important for ligand binding., Journal of Biological Chemistry, 276, (4), 2001, p2466 - 2473 Journal Article, 2001 DOI

Josefsson, E., Hartford, O., O'Brien, L., Patti, J.M. and Foster, T.J., Protection against experimental Staphylococcus aureus arthritis by vaccination with clumping factor A, a novel virulence determinant, Journal of Infectious Diseases, 184, (12), 2001, p1572 - 1580 Journal Article, 2001 DOI

Hartford, O., O'Brien, L., Schofield, K., Wells, J., Foster, T.J., The Fbe (SdrG) protein of Staphylococcus epidermidis HB promotes bacterial adherence to fibrinogen , Microbiology, 147, (9), 2001, p2545 - 2552 Journal Article, 2001 URL

Peacock, S.J., Day, N.P.J., Thomas, M.G., Berendt, A.R., Foster, T.J., Clinical isolates of Staphylococcus aureus exhibit diversity in fnb genes and adhesion to human fibronectin , Journal of Infection , 41, (1), 2000, p23 - 31 Journal Article, 2000 DOI

Kaatz, G.W., Seo, S.M., O'Brien, L., Wahiduzzaman, M., Foster, T.J., Evidence for the existence of a multidrug efflux transporter distinct from NorA in Staphylococcus aureus, Antimicrobial Agents and Chemotherapy , 44, (5), 2000, p1404 - 1406 Journal Article, 2000 DOI

Stephen N. Fitzgerald and Timothy J. Foster, Molecular Analysis of the tagF Gene, Encoding CDP-Glycerol:Poly(glycerophosphate) Glycerophosphotransferase of Staphylococcus epidermidis ATCC 14990 , Journal of Bacteriology, 182, 2000, p1046 - 1052 Journal Article, 2000 URL

Hartleib J, Köhler N, Dickinson RB, Chhatwal GS, Sixma JJ, Hartford OM, Foster TJ, Peters G, Kehrel BE, Herrmann M., Protein A is the von Willebrand factor binding protein on Staphylococcus aureus., Blood, 96, (6), 2000, p2149 - 2156 Journal Article, 2000 URL

McCrea, K.W., Hartford, O.M., Davis, S., Ni Eidhin, D., Lina, G., Speziale, P., Foster, T.J., Hook, M., The serine-aspartate repeat (Sdr) protein family in Staphylococcus epidermidis, Microbiology, 146, (7), 2000, p1535 - 1546 Journal Article, 2000 URL

Sinha, B., François, P.P., Nüße, O., Foti, M., Hartford, O.M., Vaudaux, P., Foster, T.J., (...), Krause, K.-H., Fibronectin-binding protein acts as Staphylococcus aureus invasin via fibronectin bridging to integrin α5β1 , Cellular Microbiology, 1, (2), 2000, p101 - 117 Journal Article, 2000 DOI

Fowler, T., Wann, E.R., Joh, D., Johansson, S., Foster, T.J., Höök, M., Cellular invasion by Staphylococcus aureus involves a fibronectin bridge between the bacterial fibronectic-binding MSCRAMMs and host cell β1 integrins , European Journal of Cell Biology, 79, (10), 2000, p672 - 679 Journal Article, 2000 DOI

Entenza, J.M., Foster, T.J., Eidhin, D.N., Vaudaux, P., Francioli, P., Moreillon, P., Contribution of clumping factor B to pathogenesis of experimental endocarditis due to Staphylococcus aureus , Infection and Immunity , 68, (9), 2000, p5443 - 5446 Journal Article, 2000 DOI

Molecular basis of adnerence of Staphylococcus aureus to biomaterials in, editor(s)F.A.Waldvogel and A.L.Bisno (eds.) , Infections associated with indwelling medical devices, 3rd edn., Washington D.C., American Society for Microbiology, 2000, pp.27 - 39, [Foster, T.J. and Hook, M.] Book Chapter, 2000

Francois, P., Schrenzel, J., Stoerman-Chopard, C., Favre, H., Herrmann, M., Foster, T.J., Lew, D.P., Vaudaux, P., Identification of plasma proteins adsorbed on hemodialysis tubing that promote Staphylococcus aureus adhesion, Journal of Laboratory and Clinical Medicine , 135, (1), 2000, p32 - 42 Journal Article, 2000 DOI

Peacock, S.J., Foster, T.J., Cameron, B.J., Berendt, A.R., Bacterial fibronectin-binding proteins and endothelial cell surface fibronectin mediate adherence of Staphylococcus aureus to resiting human endothelial cells, Microbiology, 145, 2000, p3477 - 3486 Journal Article, 2000 URL

Jacobs, A.A.C., Hartford, O.M., Foster, T.J., Goovaerts, D., Nuitjen, P.J.M. and Theelen, R.P.H., Investigations towards an efficacious and safe strangles vaccine: submucosal vaccination with a live attenuated Streptococcus equi., Veterinary Record, 147, (20), 2000, p563 - 567 Journal Article, 2000 URL

Staphylococcal surface proteins in, editor(s)V.A.Fischetti, R.P.Novick, J.J.Ferretti and J.I.Rood (eds.) , Gram positive bacterial pathogens, American Society for Microbiology, 1999, pp.386 - 391, [Hook, M. and Foster, T.J.] Book Chapter, 1999

Wann ER, Dassy B, Fournier JM, Foster TJ., Genetic analysis of the cap5 locus of Staphylococcus aureus., FEMS Microbiology Letters, 170, 1999, p97 - 103 Journal Article, 1999 DOI

Foster, T.J., Molecular genetic analysis of staphylococcal virulence, Methods in Microbiology, 27, 1999 Review, 1999

Glenn W. Kaatz, Susan M. Seo, and Timothy J. Foster, Introduction of a norA Promoter Region Mutation into the Chromosome of a Fluoroquinolone-Susceptible Strain of Staphylococcus aureus Using Plasmid Integration , Antimicrobial Agents and Chemotherapy, 43, (9), 1999, p2222 - 2224 Journal Article, 1999 URL

Deivanayagam CC, Perkins S, Danthuluri S, Owens RT, Bice T, Nanavathy T, Foster TJ, Höök M, Narayana SV., Crystallization of ClfA and ClfB fragments: the fibrinogen-binding surface proteins of Staphylococcus aureus., Acta Crystallographica Section D: Biological Crystallography, 55, (2), 1999, p554 - 556 Journal Article, 1999 DOI

Josefsson E, McCrea KW, Ní Eidhin D, O'Connell D, Cox J, Höök M, Foster TJ., Three new members of the serine-aspartate repeat protein multigene family of Staphylococcus aureus., Trends in Microbiology, 144, (12), 1999, p3387 - 3395 Journal Article, 1999 URL

FOSTER, TJ, ANTIBODIES THAT BLOCK ADHERENCE OF STAPHYLOCOCCUS AUREUS TO FIBRONECTIN - REPLY, 1999, 141 - 141 Miscellaneous, 1999

Staphylococcus aureus toxins in, editor(s)V.A.Fischetti, R.P.Novick, J.J.Ferretti and J.I.Rood. , Gram positive bacterial pathogens, American Society for Microbiology, 1999, pp.367 - 378, [Bohach, G.A. and Foster, T.J.] Book Chapter, 1999

Hartford O, McDevitt D, Foster TJ., Matrix-binding proteins of Staphylococcus aureus: functional analysis of mutant and hybrid molecules., Microbiology, 145, (9), 1999, p2497 - 2505 Journal Article, 1999 URL

McElroy MC, Harty HR, Hosford GE, Boylan GM, Pittet JF, Foster TJ., Alpha-toxin damages the air-blood barrier of the lung in a rat model of Staphylococcus aureus-induced pneumonia., Infection and Immunity , 67, (10), 1999, p5541 - 5544 Journal Article, 1999 URL

Peacock SJ, Lina G, Etienne J, Foster TJ., Staphylococcus schleiferi subsp. schleiferi expresses a fibronectin-binding protein., Infection and Immunity , 67, (8), 1999, p4272 - 4275 Journal Article, 1999 URL

Nilsson, I-M., Hartford, O., Foster, T. and Tarkowski, A., Alpha-toxin and gamma-toxin jointly promote Staphylococcus aureus virulence in murine septic arthritis, Infection and Immunity, 67, (3), 1999, p1045 - 1049 Journal Article, 1999 URL

Ní Eidhin D, Perkins S, Francois P, Vaudaux P, Höök M, Foster TJ., Clumping factor B (ClfB), a new surface-located fibrinogen-binding adhesin of Staphylococcus aureus., Molecular Microbiology, 30, (2), 1998, p245 - 257 Journal Article, 1998 DOI

Foster TJ, Höök M., Surface protein adhesins of Staphylococcus aureus., by Hook, M , Trends in Microbiology, 6, (12), 1998 Review, 1998 DOI

O'Connell DP, Nanavaty T, McDevitt D, Gurusiddappa S, Höök M, Foster TJ., The fibrinogen-binding MSCRAMM (clumping factor) of Staphylococcus aureus has a Ca2+-dependent inhibitory site., Journal of Biological Chemistry, 273, (12), 1998, p6821 - 6829 Journal Article, 1998 DOI

Josefsson E, O'Connell D, Foster TJ, Durussel I, Cox JA., The binding of calcium to the B-repeat segment of SdrD, a cell surface protein of Staphylococcus aureus., Journal of Biological Chemistry, 273, (47), 1998, p31145 - 31152 Journal Article, 1998 DOI

Mempel, M., Schmidt, T., Weidinger, S., Schnopp, C., Foster, T., Ring, J. and Abeck, D., Role of Staphylococcus aureus surface-associated proteins in the attachment to cultured HaCaT keratinocytes in a new adhesion assay, Journal of Investigative Dermatology, 111, 1998, p452 - 456 Journal Article, 1998 DOI

Supersac G, Piémont Y, Kubina M, Prévost G, Foster TJ., Assessment of the role of gamma-toxin in experimental endophthalmitis using a hlg-deficient mutant of Staphylococcus aureus. , Microbial Pathogenesis, 24, (4), 1998, p241 - 251 Journal Article, 1998 DOI

Marsden MJ, Vaughan LM, Fitzpatrick RM, Foster TJ, Secombes CJ., Potency testing of a live, genetically attenuated vaccine for salmonids., Vaccine, 16, (11-12), 1998, p1087 - 1094 Journal Article, 1998 DOI

Pierre E. Vaudaux, Vincenza Monzillo,,dagger Patrice Francois, Daniel P. Lew, Tim J. Foster, and Brigitte Berger-Bächi, Introduction of the mec Element (Methicillin Resistance) into Staphylococcus aureus Alters In Vitro Functional Activities of Fibrinogen and Fibronectin Adhesins , Antimicrobial Agents and Chemotherapy, 42, (3), 1998, p564 - 570 Journal Article, 1998 URL

Sau S, Bhasin N, Wann ER, Lee JC, Foster TJ, Lee CY., The Staphylococcus aureus allelic genetic loci for serotype 5 and 8 capsule expression contain the type-specific genes flanked by common genes., Microbiology, 143, (7), 1997, p2395 - 2405 Journal Article, 1997 URL

Host-pathogen protein-protein interactions in Staphylococcus in, editor(s)M.A.McCrea, J.R.Saunders, C.J.Smyth and N.D.Stow (eds.) , Molecular aspects of host-pathogen interactions, Cambridge, Cambridge University Press, 1997, pp.67 - 94., [Foster, T.J., Hartford, O. and O'Connell, D.] Book Chapter, 1997

Darouiche, R.O., Landon, G.C., Patti, J.M., Nguyen, L.L., Fernau, R.C., McDevitt, D., Greene, C., Foster, T. and Klima, M., Role of Staphylococcus aureus surface adhesins in orthopaedic device infections: are results model-dependent., Journal of Medical Microbiology, 46, 1997, p75 - 79 Journal Article, 1997 URL

O'Callaghan, R.J Foster T.J., Specific Roles of Alpha-Toxin and Beta-Toxin inStaphylococcus keratitus as established by genetic rescue experiments, 1997, - Miscellaneous, 1997

MCELROY, MC, STAPHYLOCOCCUS AUREUS ALPHA-TOXIN IS NOT THE SOLE CAUSE OF ALVEOLAR-CAPILLARY BARRIER DAMAGE IN A RAT MODEL OF BACTERIAL PNEUMONIA, unknown, 1997, 501P, ISI Web of Science, 1997, ppP61 - P61 Miscellaneous, 1997

Hartford O, Francois P, Vaudaux P, Foster TJ., The dipeptide repeat region of the fibrinogen-binding protein (clumping factor) is required for functional expression of the fibrinogen-binding domain on the Staphylococcus aureus cell surface., Molecular Microbiology, 25, (6), 1997, p1065 - 1076 Journal Article, 1997

Francois, P., Vaudaux, P., Foster, T.J. and Lew, D.P., Facteur d'attachment au fibrinogene: perspectives., Medicine at Maladies Infectieuses, 27 special, 1997, pp.1 - 7. Journal Article, 1997

Fitzpatrick, RM, Foster, TJ, Recombinant vaccines for viral Haemorrhagic septicaemia (VHS) In salmonids - Investigation of the ability of a live Bacterial Carrier to deliver antigens to fish, Developments in Biological Standardization, 90, 1997, p459 - 459 Journal Article, 1997

R J O'Callaghan, M C Callegan, J M Moreau, L C Green, T J Foster, O M Hartford, L S Engel, and J M Hill, Specific roles of alpha-toxin and beta-toxin during Staphylococcus aureus corneal infection., Infection and Immunity , 65, 1997, p1571 - 1578 Journal Article, 1997 URL

Walev, I., Weller, U., Strauch, S., Foster, T.J. and Secombes, C., Selective killing of human monocytes and cytokine release provoked by sphingomyelinase (beta-toxin) of Staphylococcus aureus, Infection and Immunity, 64, (8), 1996, p2974 - 2979 Journal Article, 1996 URL

M. J. Marsden, A. Devoy, L. M. Vaughan, T. J. Foste and C. J. Secombes, Use of a genetically attenuated strain. Aeromonas salmonicida to vaccinate salmonid fish, Aquaculture International, 4, (1), 1996, p55 - 66 Journal Article, 1996 DOI

Franpois P, Vaudaux P, Foster TJ, Lew DP , Host-Bacteria Interactions in Foreign Body Infections, Infection Control and Hospital Epidemiology, 4th International Conference on the Prevention of Infection , 17, (8), 1996, pp514 - 520 Conference Paper, 1996 URL

Marsden MJ, Vaughan LM, Foster TJ, Secombes CJ., A live (delta aroA) Aeromonas salmonicida vaccine for furunculosis preferentially stimulates T-cell responses relative to B-cell responses in rainbow trout (Oncorhynchus mykiss)., Infection and Immunity , 64, (9), 1996, p3863 - 3869 Journal Article, 1996 URL

Staphylococcus in, editor(s)S.Baron (ed.) , Medical Microbiology, Galvaston, University of Texas Medical Branch, 1996, pp.187 - 197, [Foster, T.J.] Book Chapter, 1996

Wolz, C., McDevitt, D., Foster, T.J. and Cheung, A.L., Influence of agr on fibrinogen binding in Staphylococcus aureus Newman., Infection and Immunity, 64, (8), 1996, p3142 - 3147 Journal Article, 1996 URL

Greene C, Vaudaux PE, Francois P, Proctor RA, McDevitt D, Foster TJ., A low-fibronectin-binding mutant of Staphylococcus aureus 879R4S has Tn918 inserted into its single fnb gene., Microbiology, 142, (8), 1996, p2153 - 2160 Journal Article, 1996 URL

McDevitt, D., Nanavaty, T., House-Pompeo, K., Bell, E.C., Turner, N., MnIntire, L., Foster, T.J. and Hook, M., Characterization of the interaction between Staphlococcus aureus clumping factor (ClfA) and fibrinogen, European Journal of Biochemistry, 247, (1), 1996, p416 - 424 Journal Article, 1996 DOI

Malcolm J. Horsburgh, Timothy J. Foster, Peter T. Barth and John R. Coggins, Chorismate synthase from Staphylococcus aureus, Microbiology, 142, 1996, p2943 - 2950 Journal Article, 1996 DOI

McDevitt D, Francois P, Vaudaux P, Foster TJ., Identification of the ligand-binding domain of the surface-located fibrinogen receptor (clumping factor) of Staphylococcus aureus., Molecular Microbiology, 16, (1), 1995, p895 - 907 Journal Article, 1995 DOI

Dickinson RB, Nagel JA, McDevitt D, Foster TJ, Proctor RA, Cooper SL., Quantitative comparison of clumping factor- and coagulase-mediated Staphylococcus aureus adhesion to surface-bound fibrinogen under flow., Infection and Immunity , 63, (8), 1995, p3143 - 3150 Journal Article, 1995 URL

Greene C, McDevitt D, Francois P, Vaudaux PE, Lew DP, Foster TJ., Adhesion properties of mutants of Staphylococcus aureus defective in fibronectin-binding proteins and studies on the expression of fnb genes., Molecular Microbiology, 17, (6), 1995, p1143 - 1152 Journal Article, 1995

Vaudaux PE, François P, Proctor RA, McDevitt D, Foster TJ, Albrecht RM, Lew DP, Wabers H, Cooper SL., Use of adhesion-defective mutants of Staphylococcus aureus to define the role of specific plasma proteins in promoting bacterial adhesion to canine arteriovenous shunts., Infection and Immunity , 63, (3), 1995, p585 - 590 Journal Article, 1995 URL

Shields DC, McDevitt D, Foster TJ., Evidence against concerted evolution in a tandem array in the clumping factor gene of Staphylococcus aureus., 1995, - 963-965 Miscellaneous, 1995 URL

Moreillon P, Entenza JM, Francioli P, McDevitt D, Foster TJ, François P, Vaudaux P., Role of Staphylococcus aureus coagulase and clumping factor in pathogenesis of experimental endocarditis., Infection and Immunity , 63, (12), 1995, p4738 - 4743 Journal Article, 1995 URL

Zavizion B, Bramley AJ, Politis I, Gilmore J, Turner JD, Patel AH, Foster TJ., Effects of Staphylococcus aureus toxins on the growth of bovine mammary epithelial cells (MAC-T) in culture., Journal of Dairy Science, 78, (2), 1995, p277 - 284 Journal Article, 1995 URL

McDevitt D, Foster TJ., Variation in the size of the repeat region of the fibrinogen receptor (clumping factor) of Staphylococcus aureus strains, Microbiology, 141, (4), 1995, p937 - 943 Journal Article, 1995 URL

McDevitt D, Francois P, Vaudaux P, Foster TJ., Molecular characterization of the clumping factor (fibrinogen receptor) of Staphylococcus aureus., Molecular Microbiology, 11, (2), 1994, p237 - 248 Journal Article, 1994 DOI

Genetic analysis of Staphylococcus aureus virulence in, editor(s)T.Wadstrom, I.A.Holder and G.Kronvall (eds.) , Molecular Pathogenesis of Surgical Infections: Eric K. Fernstrom Symposium, Stuttgart, Gustav Fischer Verlag, 1994, pp.11 - 29., [Foster, T.J. and McDevitt, D.] Book Chapter, 1994

Foster TJ, McDevitt D., Surface-associated proteins of Staphylococcus aureus: their possible roles in virulence., FEMS Microbiology Letters, 118, (3), 1994, p199-205 Journal Article, 1994 DOI

Genetic analysis of fibrinogen binding proteins of Staphylococcus aureus in, editor(s)R.Mollby, J.I.Flock, C.E.Nord and B.Christensson (eds.) , Staphylococci and Staphylococcal Infections , Stuttgart, Gustav Fischer Verlag, 1994, pp.358 - 360, [McDevitt, D., Vaudaux, P. and Foster, T.J.] Book Chapter, 1994

Baddour LM, Tayidi MM, Walker E, McDevitt D, Foster TJ., Virulence of coagulase-deficient mutants of Staphylococcus aureus in experimental endocarditis., Journal of Medical Microbiology, 41, (4), 1994, p259 - 263 Journal Article, 1994 URL

Molecular basis of adherence of Staphylococci to biomaterials in, editor(s)A.L.Bisno and F.A.Waldvogel (eds.) , Infections associated with indwelling devices, Washington D.C., American Society for Microbiology, 1994, pp.31 - 44., [Foster, T.J. and McDevitt, D.] Book Chapter, 1994

Dassy B, Hogan T, Foster TJ, Fournier JM., Involvement of the accessory gene regulator (agr) in expression of type 5 capsular polysaccharide by Staphylococcus aureus., Journal of General Microbiology, 139, (6), 1993, p1301 - 1306 Journal Article, 1993 URL

McDevitt D, Wann ER, Foster TJ., Recombination at the coagulase locus in Staphylococcus aureus: plasmid integration and amplification., Journal of General Microbiology, 139, (4), 1993, p695 - 706 Journal Article, 1993 URL

Farrell AM, Foster TJ, Holland KT., Molecular analysis and expression of the lipase of Staphylococcus epidermidis., Journal of General Microbiology, 139, (2), 1993, p267 - 277 Journal Article, 1993 URL

Vaughan LM, Smith PR, Foster TJ., An aromatic-dependent mutant of the fish pathogen Aeromonas salmonicida is attenuated in fish and is effective as a live vaccine against the salmonid disease furunculosis., Infection and Immunity, 61, (5), 1993, p2172 - 2181 Journal Article, 1993 URL

O'Connell C, Pattee PA, Foster TJ., Sequence and mapping of the aroA gene of Staphylococcus aureus 8325-4., Journal of General Microbiology, 139, (7), 1993, p1449 - 1460 Journal Article, 1993 URL

Poston SM, Glancey GR, Wyatt JE, Hogan T, Foster TJ., Co-elimination of mec and spa genes in Staphy/ococcus aweus and the effect of agr and protein A production on bacterial adherence to cell monolayers, Journal of Medical Microbiology, 39, (6), 1993, p422 - 428 Journal Article, 1993 URL

Cooney J, Kienle Z, Foster TJ, O'Toole PW., The Gamma-Hemolysin Locus of Staphylococcus aureus. Comprises Three Linked Genes, Two of Which Are Identical to the Genes for the F and S Components of Leukocidin, 1993, - 768-771 Miscellaneous, 1993 URL

McDevitt D, Vaudaux P, Foster TJ., Genetic evidence that bound coagulase of Staphylococcus aureus is not clumping factor., Infection & Immunity, 60, (4), 1992, p1514 - 1523 Journal Article, 1992 URL

Sheehan BJ, Foster TJ, Dorman CJ, Park S, Stewart GS., Osmotic and growth-phase dependent regulation of the eta gene of Staphylococcus aureus: a role for DNA supercoiling., Molecular and General Genetics, 232, (1), 1992, p49 - 57 Journal Article, 1992 DOI

The use of mutants for defining the role of virulence factors in vivo. in, editor(s)C.Hormaeche, C.W.Penn and C.J.Smyth (eds.). , Molecular biology of bacterial infection: current status and future perspectives, Cambridge, Cambridge University Press, 1992, pp.171 - 191, [Foster, T.J.] Book Chapter, 1992

Patel AH, Kornblum J, Kreiswirth B, Novick R, Foster TJ., 2.Regulation of the protein A-encoding gene in Staphylococcus aureus., Gene, 114, (1), 1992, p25 - 34 Journal Article, 1992 DOI

Genetic analysis of the in vivo role of bacterial toxins. in, editor(s)J.E.Alouf and J.H.Freer (eds.). , Sourcebook of bacterial protein toxins, Academic Press, 1991, pp.445 - 459, [Foster, T.J.] Book Chapter, 1991

Sloane R, de Azavedo JC, Arbuthnott JP, Hartigan PJ, Kreiswirth B, Novick R, Foster TJ., A toxic shock syndrome toxin mutant of Staphylococcus aureus isolated by allelic replacement lacks virulence in a rabbit uterine model., FEMS Microbiology Letters, 78, (2-3), 1991, p239 - 244 Journal Article, 1991 DOI

Foster TJ., Potential for vaccination against infections caused by Staphylococcus aureus., Vaccine, 9, (4), 1991 Review, 1991 DOI

Redpath MB, Foster TJ, Bailey CJ., The role of the serine protease active site in the mode of action of epidermolytic toxin of Staphylococcus aureus., FEMS Microbiology Letters, 65, (2), 1991, p151 - 156 Journal Article, 1991 DOI

Susceptibility to opsonophagocytosis of protein A, alpha-haemolysin and beta-toxin deficient mutants of Staphylococcus aureus isolated by allele-replacement in, Zentralblatt fur Bakteriologie (Supplement 21), Stuttgart, Gustav Fischer Verlag, 1991, pp.273 - 277, [Gemmell, C.G., Tree, R., Patel, A., O'Reilly, M. and Foster, T.J.] Book Chapter, 1991

Vaughan L, Smith P, Foster TJ., Aromatic-dependent mutants of Aeromonas salmonicida., Research In Microbiology, 141, (7-8), 1991, p941 - 943 Journal Article, 1991 DOI

Phonimdaeng P, O'Reilly M, Nowlan P, Bramley AJ, Foster TJ., The coagulase of Staphylococcus aureus 8325-4. Sequence analysis and virulence of site-specific coagulase-deficient mutants., Molecular Microbiology, 4, (3), 1990, p393 - 404 Journal Article, 1990 DOI

Genetic studies of virulence factors of Staphylococcus aureus. Role of alpha-toxin, beta-toxin, protein A and coagulase in virulence of S.aureus in the mouse mammary gland. in, editor(s)T.Wadstrom, I.Eliasson, I.Holder and A.Ljungh (eds.) , Pathogenesis of wound and biomaterial-associated infections., London, Springer-Verlag, 1990, pp.35 - 46, [Foster, T.J., O'Reilly, M. and Bramley, A.J.] Book Chapter, 1990

Genetic studies of virulence factors of Staphylococcus aureus. Properties of coagulase and gamma-toxin and the role of alpha-toxin, beta-toxin and protein A in the pathogenesis of S.aureus infections. in, editor(s)R.P.Novick (ed.) , Molecular Biology of the Staphylococci, Cambridge, VCH, 1990, pp.403 - 417., [Foster, T.J., O'Reilly, M., Phonimdaeng, P., Cooney, J., Patel, A.H. and Bramley, A.J.] Book Chapter, 1990

O'Reilly M, Kreiswirth B, Foster TJ., Cryptic alpha-toxin gene in toxic shock syndrome and septicaemia strains of Staphylococcus aureus., Molecular Microbiology, 4, (11), 1990, p1947 - 1955 Journal Article, 1990

Molecular analysis of a non-expressed alpha-toxin gene of clinical strains of Staphylococcus aureus in, editor(s)R.P.Novick (ed.) , Molecular biology of the Staphylococci, Cambridge, VCH, 1990, pp.439 - 444, [O'Reilly, M., Kreisworth, B.N. and Foster, T.J.] Book Chapter, 1990

Cloning and expression of the lipase gene of Staphylococcus epidermidis in Escherichia coli and Staphylococcus aureus in, editor(s)R.P.Novick (ed.). , Molecular biology of the Staphylococci, Cambridge, VCH, 1990, pp.451 - 454., [Farrell, A.M., Holland, K.T. and Foster, T.J.] Book Chapter, 1990

Martha Hennigan, Laurence M. Vaughan, Timothy J. Foster, Peter Smith, and Frank Gannon, Characterization of Aeromonas salmonicida Strains using DNA Probe Technology, Canadian Journal of Fisheries and aquatic sciences, 46, (5), 1989, p877 - 879 Journal Article, 1989 DOI

Bramley AJ, Patel AH, O'Reilly M, Foster R, Foster TJ., Roles of alpha-toxin and beta-toxin in virulence of Staphylococcus aureus for the mouse mammary gland., Infection and Immunity, 57, (8), 1989, p2489 - 2494 Journal Article, 1989 URL

Arvind H. Patel, Timothy J. Foster and Peter A. Pattee, Physical and Genetic Mapping of the Protein A Gene in the Chromosome of Staphylococcus aureus 8325-4, Journal of General Microbiology, 135, 1989, p1799 - 1807 Journal Article, 1989 DOI

Foster TJ, O'Reilly M, Patel AH, Bramley AJ., Genetic studies of Staphylococcus aureus virulence factors., Antonie Van Leeuwenhoek, 54, (5), 1988, p475 - 482 Journal Article, 1988 DOI

Detection and use of transposons in, editor(s)J.Grinsted and P.M.Bennett , Methods in Microbiology Vol.21, London, Academic Press, 1988, pp.205 - 231, [Bennett, P.M., Grinsted, J. and Foster, T.J.] Book Chapter, 1988

Cooney J, Mulvey M, Arbuthnott JP, Foster TJ., Molecular cloning and genetic analysis of the determinant for gamma-lysin, a two-component toxin of Staphylococcus aureus., Journal of General Microbiology , 134, (8), 1988, p2179 - 2188 Journal Article, 1988 URL

Phonimdaeng, P., M. O'Reilly, O'Toole, P and Foster TJ, Molecular Cloning and Expression of the Coagulase Gene of Staphylococcus aureus 8325-4, Journal of General Microbiology, 134, 1988, p75 - 83 Journal Article, 1988 URL DOI

M J Storrs, P Courvalin, and T J Foster, Genetic analysis of gentamicin resistance in methicillin- and gentamicin-resistant strains of Staphylococcus aureus isolated in Dublin hospitals., Antimicrobal Agents and Chemotherapy, 32, (8), 1988, p1174 - 1181 Journal Article, 1988 URL TARA - Full Text

GEMMELL, CG, DIFFERENCES IN OPSONOPHAGOCYTOSIS OF STAPHYLOCOCCUS-AUREUS MUTANTS DEFICIENT IN PROTEIN-A, ALPHA-HEMOLYSIN AND BETA-TOXIN, unknown, 1988, 25, ISI Web of Science, 1988, ppR16 - R16 Miscellaneous, 1988

Genetic analysis of the role of toxins and protein A in the pathogenesis of Staphylococcus aureus infections. Properties of an unexpressed alpha-toxin locus from a clinical isolate. in, editor(s)J.E.Alouf, F.J.Fehrenbach, J.Jeliaszewicz and M.Thelestam (eds.) , Bacterial Protein Toxins, Stuttgart, New York, Gustav Fischer Verlag, 1988, pp.343 - 349, [Foster, T.J., O'Reilly, M., Patel, A.H., Nowlan,P. and Bramley, A.J.] Book Chapter, 1988

Patel, A., Nowlan, P., Weavers, E.A. and Foster, T.J., Virulence of protein A-deficient and alpha-toxin-deficient mutants of Staphylococcus aureus isolated by allele replacement, Infection and Immunity, 55, (12), 1987, pp.3101 - 3110. Journal Article, 1987 URL

Foster TJ., The genetics and biochemistry of mercury resistance., Critical Reviews in Microbiology, 15, (2), 1987, p117-140 Review, 1987 DOI

O'Toole PW, Foster TJ., Nucleotide sequence of the epidermolytic toxin A gene of Staphylococcus aureus., Journal of Bacteriology, 169, (9), 1987, p3910 - 3915 Journal Article, 1987 URL

FOSTER, TJ, RECOMBINANT-DNA TECHNIQUES AND SPECIFIC GENE INACTIVATION IN THE ANALYSIS STAPHYLOCOCCUS-AUREUS VIRULENCE, unknown, 1986, 22, ISI Web of Science, 1987, ppR6 - R7 Miscellaneous, 1987

STORRS, MJ, AMINOGLYCOSIDE RESISTANCE IN MULTIRESISTANT STAPHYLOCOCCUS-AUREUS, unknown, 1986, 22, ISI Web of Science, 1987, ppR14 - R14 Miscellaneous, 1987

H G Griffin, T J Foster, S Silver, and T K Misra, Cloning and DNA sequence analysis of the mercuric and organomercurial resistance determinants of plasmid pDU1358., Proceedings of the National Academy of Science, 84, (10), 1987, p3112 - 3116 Journal Article, 1987 URL

Genetic analysis of Staphylococcus aureus virulence. in, editor(s)P.Owen and T.J.Foster (eds.) , Immunochemical and molecular genetic analysis of bacterial pathogens, Amsterdam, Elsevier Science Publishers, 1987, pp.103 - 119, [Foster, T.J., O'Toole, P.W. and O'Reilly, M.] Book Chapter, 1987

O'Reilly M, de Azavedo JC, Kennedy S, Foster TJ., Inactivation of the alpha-haemolysin gene of Staphylococcus aureus 8325-4 by site-directed mutagenesis and studies on the expression of its haemolysins, Microbial Pathogenesis, 1, (2), 1986, p125 - 138 Journal Article, 1986 DOI

Paul W. O'Toole and Timothy J. Foster, Epidermolytic toxin serotype B of Staphylococcus aureus is plasmid-encoded , FEMS Microbiology Letters, 36, (2-3), 1986, p311 - 314 Journal Article, 1986

Coleman DC, Cafferkey M, Keane CT, Baxter L, Pomeroy H, Foster TJ, Hone R, Mulvey M, Arbuthnott JP., Mechanisms of pathogenicity of multi-resistant Staphylococcus aureus., Journal of Hospital Infection, 7, (Suppl A), 1986, p29 - 35 Journal Article, 1986

Bhriain NN, Foster TJ., Polypeptides specified by the mercuric resistance (mer) operon of plasmid R100., Gene, 42, (3), 1986, p323 - 330 Journal Article, 1986 DOI

O'Toole PW, Foster TJ., Molecular cloning and expression of the epidermolytic toxin A gene of Staphylococcus aureus., Microial Pathogenesis, 1, (6), 1986, p583 - 594 Journal Article, 1986 DOI

Dorman, C.J., Foster, T.J. and Shaw, W.V., Nucleotide sequence of the R26 chloramphenicol resistance determinant and identification of its gene product, Gene, 41, 1986, pp.349 - 353. Journal Article, 1986

Foster, T. J., A new genetic approach to defining the virulence determinants of Staphylococcus aureus strains that cause bovine mastitis., Irish Veterinary Journal, 40, (7-8), 1986, p110 - 115 Journal Article, 1986

Dorman CJ, Foster TJ, Shaw WV., Nucleotide sequence of the R26 chloramphenicol resistance determinant and identification of its gene product., Gene, 41, (2-3), 1986, p349-353 Journal Article, 1986 DOI

Foster TJ, Ginnity F., Some mercurial resistance plasmids from different incompatibility groups specify merR regulatory functions that both repress and induce the mer operon of plasmid R100., Journal of Bacteriology, 162, (2), 1985, p773 - 776 Journal Article, 1985 URL

Coleman DC, Pomeroy H, Estridge JK, Keane CT, Cafferkey MT, Hone R, Foster TJ., Susceptibility to antimicrobial agents and analysis of plasmids in gentamicin- and methicillin-resistant Staphylococcus aureus from Dublin hospitals., Journal of Medical Microbiology, 20, (2), 1985, p157 - 167 Journal Article, 1985 URL

Dorman CJ, Foster TJ., Posttranscriptional regulation of the inducible nonenzymatic chloramphenicol resistance determinant of IncP plasmid R26., Journal of Bacteriology, 161, (1), 1985, p147 - 152 Journal Article, 1985 URL

Griffin HG, Foster TJ, Falkiner FR, Carr ME, Coleman DC., Molecular analysis of multiple-resistance plasmids transferred from gram-negative bacteria isolated in a urological unit., Antimicrobal Agents and Chemotherapyi, 28, (3), 1985, p413 - 418 Journal Article, 1985 URL

Foster TJ, Brown NL., Identification of the merR gene of R100 by using mer-lac gene and operon fusions., Journal of Bacteriology, 163, (3), 1985, p1153 - 1157 Journal Article, 1985 URL

J C de Azavedo, T J Foster, P J Hartigan, J P Arbuthnott, M O'Reilly, B N Kreiswirth and R P Novick , Expression of the cloned toxic shock syndrome toxin 1 gene (tst) in vivo with a rabbit uterine model., Infection and Immunity, 50, (1), 1985, p304 - 309 Journal Article, 1985 URL

Analysis of plasmid functions with transposons in, editor(s)P.Bennett and J.Grinstead (eds.) , Methods in Microbiology Vol.17, London, Academic Press, 1984, ppp.197 - 226., [Foster, T.J.] Book Chapter, 1984

Coleman DC, Chopra I, Shales SW, Howe TG, Foster TJ., Analysis of tetracycline resistance encoded by transposon Tn10: deletion mapping of tetracycline-sensitive point mutations and identification of two structural genes., Journal of Bacteriology, 153, (2), 1983, p921 - 929 Journal Article, 1983 URL

DORMAN, CJ, ANALYSIS OF THE CHLORAMPHENICOL RESISTANCE DETERMINANT OF PLASMID-R26, unknown, 1983, 51, ISI Web of Science, 1983, pp525 - 525 Miscellaneous, 1983

Fairweather N, Kennedy S, Foster TJ, Kehoe M, Dougan G., Expression of a cloned Staphylococcus aureus alpha-hemolysin determinant in Bacillus subtilis and Staphylococcus aureus., Infection and Immunity, 41, (3), 1983, p1112 - 1117 Journal Article, 1983 URL

T J Foster, Plasmid-determined resistance to antimicrobial drugs and toxic metal ions in bacteria., Microbiological Reviews, 47, (3), 1983, p361-409 Review, 1983 URL

Kehoe, M., Duncan, J., Foster, T., Fairweather, N. and Dougan, G., Cloning expression and mapping of the Staphylococcus aureus alpha-haemolysin determinant in Escherichia coli K12, Infection and Immunity, 41, 1983, pp.1105 - 1111 Journal Article, 1983

Ni'Bhriain NN, Silver S, Foster TJ., Tn5 insertion mutations in the mercuric ion resistance genes derived from plasmid R100., Journal of Bacteriology, 155, (2), 1983, p690 - 703 Journal Article, 1983 URL

BHRIAIN, NN, GENETIC-ANALYSIS OF THE MERCURIC RESISTANCE DETERMINANT OF R100, unknown, 1983, 51, ISI Web of Science, 1983, pp525 - 525 Miscellaneous, 1983

Dorman, CJ and Foster, TJ, Nonenzymatic Chloramphenicol Resistance Determinants. Specified by Plasmids R26 and R55-1 in Escherichia coli K-12. Do Not Confer High-Level Resistance to Fluorinated Analogs, Antimicrobal Agents and Chemotherapy, 22, (5), 1982, p912-914 Journal Article, 1982 URL

Dorman, C.J. and Foster, T.J., Nonenymatic chlorampenicol resistance determinants specified by plasmids R26 and R55-1 in Escheria coli K12 do not confer high-level resistance in fluorinated analogs, Antimicrobial Agents and Chemotherapy, 22, 1982, pp.912 - 914. Journal Article, 1982

Foster, T.J., Davies, M.A., Roberts, D.E., Takeshita, K. and Kleckner, N., Genetic organization of transposon Tn10, Cell, 23, (1), 1981, p215 - 227 Journal Article, 1981 DOI

Foster, T.J., Lundblad, V. Hanley-Way, S., Halling, S.M. and Kleckner, N., Three Tn10 associated excision events: relationship to transposition and role of direct and inverted repeats., Cell, 23, (1), 1981, p201 - 213 Journal Article, 1981 DOI

Coleman DC, Foster TJ., Analysis of the reduction in expression of tetracycline resistance determined by transposon Tn10 in the multicopy state., Molecular and General Genetics, 182, (1), 1981, p171 - 177 Journal Article, 1981

Kleckner, N. Foster, T.J., Davies, M.A., Hanley-Way, S., Halling, S.V., Lundblad, V. and Takeshita, K., Genetic organization of transposon Tn10 and analysis of Tn10-associated events, Cold Spring Harbor Symposium of Quantitative Biology, 45, 1981, p225 - 238 Journal Article, 1981

O'Reilly M, Dougan G, Foster TJ, Arbuthnott JP., Plasmids in epidermolytic strains of Staphylococcus aureus., Journal of General Microbiology, 124, (1), 1981, p99 - 107 Journal Article, 1981 URL

Gaffney DF, Cundliffe E, Foster TJ., Chloramphenicol resistance that does not involve chloramphenicol acetyltransferase encoded by plasmids from gram-negative bacteria., Journal of General Microbiology, 125, (1), 1981, p113 - 121 Journal Article, 1981 URL

Kehoe, M.A. and Foster, T.J., Transposon 10 promoted deletions and inversions in the transfer genes of R100-1, Molecular and General Genetics, 176, (1), 1979, p113 - 120 Journal Article, 1979

Properties of drug resistance transposons, with particular reference to Tn10. in, editor(s)C.Stuttard and K.P.Rozee (eds.) , Plasmids and transposons; environmental effects and maintenance mechanisms, New York, Academic Press, 1979, pp.207 - 224, [Foster, T.J. and Kleckner, N.] Book Chapter, 1979

Foster, T.J. and Nakahara, H., Deletions in the r-determinant mer region of plasmid R100-1 selected by loss of mercury hypersensitivity, Journal of Bacteriology, 140, (1), 1979, p301 - 305 Journal Article, 1979 URL

Foster, T.J., Nakahara, H., Weiss, A.A. and Silver, S., Transposon A-generated mutations in the mercuric resistance genes of plasmid R100-1, Journal of Bacteriology, 140, (1), 1979, p167 - 181 Journal Article, 1979 URL

Gaffney, D.F., Foster, T.J. and Shaw, W.V., Chloramphenicol acetyltransferases determined by R plasmids from gram-negative bacteria, Journal of General Microbiology, 109, 1978, p351 - 358 Journal Article, 1978 DOI

Foster, T.J. and Willetts, N.S., Characterization of transfer-deficient mutants of the R100-1 Tcs plasmid pDU202, caused by the insertion of the Tn10., Molecular and General Genetics, 156, 1977, p107 - 114 Journal Article, 1977

Kehoe, M.A. and Foster, T.J., Genetic analysis of mutations in the transfer genes of pDU202 tra::Tn10 plasmids, caused by the excision of Tn10, Molecular and General Genetics, 157, 1977, p109 - 118 Journal Article, 1977

Foster, T.J., Isolation and characterisation of mutants of R100-1 whic express tetracycline resistance constitutively, FEMS Microbiology Letters, 2, (5), 1977, p271 - 274 Journal Article, 1977 DOI

Foster, T.J. , Insertion of the tetracycline resistance transloction unit Tn10 in the lac operation of Escherichia coli, Molecular and General Genetics, 154, (3), 1977, p305 - 309 Journal Article, 1977 DOI

Foster, T.J. and Willetts, N.S., Genetic analysis of deletions of R100-1 that are both transfer-deficient and tetracycline-sensitive, Journal of General Microbiology, 93, (1), 1976, p133 - 140 Journal Article, 1976 URL

Foster, T.J., R factor tetracycline and chloramphenicol resistance in Escherichia coli K12 cmlB mutants, Journal of General Microbiology, 90, (2), 1975, ppp.303 - 310 Journal Article, 1975 URL

Foster, T.J., Tetracycline sensitive mutants of the F-like R factors R100 and R100-1, Molecular and General Genetics, 137, (1), 1975, p85 - 88 Journal Article, 1975

Foster, T.J., Howe, T.G.B. and Richmond, K.M.V., Translocation of the tetracycline resistance determinant from R100-1 to the Escherichia coli K12 chromosome, Journal of Bacteriology , 124, (3), 1975, p1153 - 1158 Journal Article, 1975 URL

Foster, T.J. and Walsh, A., Phenotypic characterization of R-factor tetracycline resistance determinants, Genetical Research, Cambridge, 24, (3), 1974, ppp.333 - 343 Journal Article, 1974 DOI

Foster, T.J. and Howe, T.G.B., Deletion map of the chloramphenicol resistance region of R1 and R100-1, Journal of Bacteriology, 116, (2), 1973, p1062 - 1063 Journal Article, 1973 URL

Foster, T.J. and Shaw, W.V., Chloramphenicol acetyltransferases specified by fi-R factors, Antimicrobial Agents and Chemotherapy, 3, (1), 1973, p99 - 104 Journal Article, 1973 URL

Foster, T.J. amd Howe, T.G.B., Chloramphenicol acetyltransferase formed by wild-type and complementing R factors in Escherichia coli K12, Journal of General Microbiology, 71, 1972, p575 - 580 Journal Article, 1972 URL

Foster, T.J. and Howe, T.G.B., Recombination and complementation between R factors in Escherichia coli K12, Genetical Research, Cambridge, 18, 1971, ppp.287 - 297 Journal Article, 1971 DOI

Non-Peer-Reviewed Publications

Paul K. Gorecki, Anne Nolan, Aoife Brick, Seán Lyons, Delivery of Pharmaceuticals in Ireland Getting a Bigger Bang for the Buck, Dublin, ESRI, January, 2012, 1-161 Report, 2012 URL

Foster, T.J. , Staphylococci and staphylococcal infections, Expert Review of Anti-Infective Therapy, 8, (12), 2010, p1337 - 1338 Journal Article, 2010 TARA - Full Text

Research Expertise

Keywords

Antibiotic resistance mechanisms; Antibiotics; BIOFILMS; Biomedical Research Training; BOVINE MASTITIS; CLONING VECTORS; CLUMPING FACTOR; COLLAGEN ADHESIN; ENDOTHELIAL-CELLS; EPIDERMOLYTIC TOXIN; FIBRINOGEN; FIBRONECTIN; FIBRONECTIN-BINDING PROTEINS; FOREIGN-BODY INFECTION; GRAM-POSITIVE BACTERIA; HEMOLYSIN; Immune evasion mechanisms; Infectious Diseases/Agents; LEUKOCYTES; Microbiology; Molecular Cloning; Proteins and Macromolecules; Recombinant DNA; STAPHYLOCOCCUS-AUREUS; TOXIC SHOCK SYNDROME TOXIN; Vaccine; Vaccine development, delivery & adjuvants; Vaccinology; virulence factors

Recognition

Representations

Public Health Services Research Fellow, National Institutes of Health. Department of Biochemistry and Molecular Biology, Harvard University 1978-79

Consultant to SmithKline Beecham, UK 1990-1995

Consultant to PanTherix, Glasgow 2000-2002

Ad hoc consultancy to Zeneca, Intercell, American Cyanamid, Unilever, Pantherix

Ad hoc consultant to Environmental Protection Agency, Ireland. Live-attenuated cholera vaccine license

External member of promotion/tenure committee, University College Galway 1995

External member of promotion/tenure committee, St George's Hospital London 2003

Regular reviewer of grant applications. The Wellcome Trust, The Medical Research Council UK, BBSRC UK

Member of Health Research Board Committee, Microbiology Mechanisms of Infectious Disease and Host Defence 2001 - present

Reviewer for DFG Cluster of Excellence, Bonn, Germany June 2006

Scientific Advisory Board member for ISSSI (International Symposium of Staphylococci and Staphylococcal Infections) VII (1992), VIII (1996), IX (2000), X (2002), XI (2004), XII (2006), X1V (2010) 1992 - present

Invited speaker at 40 international conferences in USA, UK, and Far East and Europe since 1985 1985 -

Wellcome Trust Advanced Techniques laboratory course in Bacterial Pathogens, Hinxton, Cambridge. Tutor in laboratory. 2007, 2008, 2009

Awards and Honours

Public Health Service International Research Fellow, U.S. Department of Health and Human Services, National Institutes of Health. 1978-1979

Elected to Fellowship of Trinity College Dublin 1981

E.S. and R. Duthie Lecture, Trinity College Dublin 2003

Memberships

Editorial Board of 'Molecular Microbiology' 1990 – - present

Member of Scientific Advisory Board of Inhibitex Inc, Alpharetta, Georgia, USA 1998-2006 – present

Editorial Board of 'Microbial Drug Resistance' 2002 – - present

Editorial Board of 'Microbiology' 1990 – 1995

Editorial Board of 'Journal of Bacteriology' 1983 – 1989

Editorial Board of "Infection and Immunity" 2008

Member of American Society for Microbiology 1972

Member of Society for General Microbiology 1973