Tony Mc Elligott
Assistant Prof in Molecular Haematology, Haematology
Assistant Prof in Molecular Haematology, Molecular Medicine Ireland

Publications and Further Research Outputs

Peer-Reviewed Publications

McElligott, AM, Maginn, EN, Greene, LM, McGuckin, S, Hayat, A, Browne, PV, Butini, S, Campiani, G, Catherwood, MA, Vandenberghe, E, Williams, DC, Zisterer, DM, Lawler, M, The Novel Tubulin-Targeting Agent Pyrrolo-1,5-Benzoxazepine-15 Induces Apoptosis in Poor Prognostic Subgroups of Chronic Lymphocytic Leukemia., Cancer Research, 69, (21), 2009, p8366 - 8375 Journal Article, 2009 DOI

Maginn EN, Browne PV, Hayden P, Vandenberghe E, McDonagh B, Evans P, Goodyer M, Tewari P, Campiani G, Butini S, Williams DC, Zisterer DM, Lawler MP, McElligott AM., PBOX-15, a novel microtubule targeting agent, induces apoptosis, upregulates death receptors, and potentiates TRAIL-mediated apoptosis in multiple myeloma cells., British Journal of Cancer, 104, (2), 2011, p281 - 289 Journal Article, 2011 DOI

Lysaght J, Verma NK, Maginn EN, Ryan JM, Campiani G, Zisterer DM, Williams DC, Browne PV, Lawler MP, McElligott AM., The microtubule targeting agent PBOX-15 inhibits integrin-mediated cell adhesion and induces apoptosis in acute lymphoblastic leukaemia cells, International Journal of Oncology, 42, (1), 2013, p239 - 249 Journal Article, 2013 DOI TARA - Full Text

S A Bright, A M McElligott, J W O'Connell, L O'Connor, P Carroll, G Campiani, M W Deininger, E Conneally, M Lawler, D C Williams, and D.M Zisterer, Novel pyrrolo-1,5-benzoxazepine compounds display significant activity against resistant chronic myeloid leukaemia cells in vitro, in ex vivo patient samples and in vivo , British Journal of Cancer, 102, 2010, p1474 - 1482 Journal Article, 2010 TARA - Full Text

Greene LM, Nathwani SM, Bright SA, Fayne D, Croke A, Gargliardi M, Mc Elligott AM, O'Connor L, Carr M, Keely NO, O'Boyle NM, Carroll P, Sarkadi B, Conneally E, Lloyd DG, Lawler M, Meegan MJ, Zisterer DM, The vascular targeting agent Combretastatin-A4 and a novel cis-restricted {beta}-lactam analogue CA-432 induce apoptosis in human chronic myeloid leukemia cells and in ex vivo patient samples including those displaying multidrug resistance., The Journal of Pharmacology and Experimental Therapeutics, 335, (2), 2010, p302 - 313 Journal Article, 2010 DOI

Langabeer SE, Quinn F, O'Brien D, McElligott AM, Kelly J, Browne PV, Vandenberghe E, Incidence of the BRAF V600E mutation in chronic lymphocytic leukaemia and prolymphocytic leukaemia, Leukemia Research, 36, (4), 2012, p483 - 484 Journal Article, 2012

Langabeer S, O'Brien D, McElligott AM, Lavin M, Browne P, BRAF V600E-negative hairy cell leukaemia, Case Reports in Hematology, 2013 Journal Article, 2013 TARA - Full Text DOI

Verma, NK, Dempsey, E, Conroy, J, Olwell, P, McElligott, AM, Davies, AM, Kelleher, D, Butini, S, Campiani, G, Williams, DC, Zisterer, DM, Lawler, M, Volkov, Y, A new microtubule-targeting compound PBOX-15 inhibits T-cell migration via post-translational modifications of tubulin., Journal of Molecular Medicine , 86, (4), 2008, p457- 469 Journal Article, 2008 DOI TARA - Full Text

Cunningham, O, McElligott, AM, Carroll, AM, Breen, E, Reguenga, C, Oliveira, ME, Azevedo, JE, Porter, RK, Selective detection of UCP 3 expression in skeletal muscle: effect of thyroid status and temperature acclimation., Biochimica et biophysica acta, 1604, (3), 2003 Journal Article, 2003

Forde JC., Maginn EN., McNamara G., Martin LM., Campiani GC. , Williams DC, Zisterer D.M, McElligott AM., Lawler M, , Lynch TH, Hollywood D., Marignol L, Microtubule-Targeting-Compound PBOX-15 Radiosensitizes Cancer Cells In Vitro , Cancer Biology and Therapy, 11, (4), 2011, p6 - 13 Journal Article, 2011

Bright SA, McElligott AM, O'Connell JW, O'Connor L, Carroll P, Campiani G, Deininger MW, Conneally E, Lawler M, Williams DC, Zisterer DM., Novel pyrrolo-1,5-benzoxazepine compounds display significant activity against resistant chronic myeloid leukaemia cells in vitro, in ex vivo patient samples and in vivo., British Journal of Cancer, 102, (10), 2010, p1474 - 1482 Journal Article, 2010

Reid, HM, McElligott, AM, McGlynn, H, Phenotypic alterations in Caki-1 cells as a consequence of TIMP-1 overexpression., Cancer letters, 169, (2), 2001 Journal Article, 2001

Non-Peer-Reviewed Publications

Anthony Davies, Anthony McElligott, Graham Pidgeon, Anthony Ryan, Ruth Foley, Cancer Biology where do we go next?, European Pharmaceutical Review, (1), 2010 Journal Article, 2010

Research Expertise

Keywords

Apoptosis; Biology and therapy of myeloma; Drug development and evaluation; Haemotology; Leukemias and lymphomas; Multiple Myeloma

Recognition

Memberships

Irish Association for Cancer Research 1995

Haematology Association of Ireland 2001

American Association for Cancer Research 2004

European Association for Cancer Research 2006