About our Research

Our research focusses on virulence gene regulation, antibiotic resistance, and RNA biology of Gram-negative bacterial pathogens using Salmonella enterica and Acinetobacter baumannii as model organisms.

To adapt and respond to changing conditions during infection and in the environment, bacteria possess the remarkable ability to modulate their gene expression programs quickly and efficiently. We use whole genome (Next-Generation Sequencing, RNA-seq) and gene-specific methods to study transcriptional networks, mechanisms, and antibiotic resistance of Gram-negative pathogens and their regulation (by small RNAs and protein transcription factors) to understand how bacterial pathogens sense, respond, and survive during environmental changes.

 

Current collaborators:

  • Jay C.D. Hinton, University of Liverpool, UK
  • Andrew D.S. Cameron, University of Regina, Canada
  • Tzu-Chiao Chao, University of Regina, Canada
  • Shabarinath Srikumar, University College Dublin, Ireland
  • Kristina Schauer, Ludwig-Maximilians Universität München, Germany
  • Thilo M. Fuchs, Friedrich-Loeffler-Institut Jena, Germany
  • Karsten Hokamp, Trinity College Dublin, Ireland
  • Marc Erhardt, Humboldt University, Berlin, Germany

 

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