Publications

Kearney CJ and Martin SJ (2017) An Inflammatory Perspective on Necroptosis. Molecular Cell, in press.

Henry CM and SJ Martin (2017) Caspase-8 acts in a Non-Enzymatic Role as a Scaffold for assembly of a pro-inflammatory 'FADDosome' complex in response to TRAIL stimulation. Molecular Cell, In Press

Henry CM, Sullivan GP, Clancy DM, Afonina IS, Kulms D, and SJ Martin. (2016) Neutrophil-Derived Proteases Escalate Inflammation through Activation of IL-36 Family Cytokines. Cell Reports 14, 708-22.

Afonina IS, Müller C, Martin SJ, Beyaert R. (2015) Proteolytic Processing of Interleukin-1 Family Cytokines: Variations on a Common Theme. Immunity 42, 991-1004.

Cullen SP, Kearney CJ, Clancy DM, and SJ Martin (2015) Diverse Activators of the NLRP3 Inflammasome Promote IL-1β Secretion by Triggering Necrosis. Cell Reports 11, 1535-48.

Hollville, E., Carroll, R. and S.J. Martin (2014) Bcl-2 Family Proteins Participate in Mitochondrial Quality Control by Regulating Parkin/PINK1-Dependent Mitophagy. Molecular Cell 55, 451-466.

Carroll, R., Hollville, E. and S.J. Martin (2014) Parkin sensitizes towards apoptosis induced by mitochondrial depolarization through promoting degradation of Mcl-1. Cell Reports, 9, 1538-53.

Carroll, R. and S. J. Martin (2013) Autophagy and Multiple Myeloma: What makes you Stronger Can Also Kill you. Cancer Cell, 23, 425-6.

Cullen, SP, Henry CM, Kearney, CJ, Logue SE, Feoktistova M, Tynan GA, Lavelle EC, Leverkus M, and Martin SJ (2013) Fas/CD95-Induced Chemokines can Serve as 'Find-Me' Signals for Apoptotic Cells. Molecular Cell, 49, 1034-1048.

Hollville, E. and S.J. Martin (2012) Greasing the path to Bax/Bak activation and apoptosis. Cell 148, 845-846.

Martin SJ, Henry CM, Cullen SP. (2012) A perspective on mammalian caspases as positive and negative regulators of inflammation. Molecular Cell 46, 387-97

Martin, S.J. (2010) Opening the cellular poison cabinet. Science 330, 1330-1331.

Elgendy, M., Sheridan, C., Brumatti, G. and S.J Martin (2011) Oncogenic Ras-Induced Expression of Noxa and Beclin-1 Promotes Autophagic Cell Death and Limits Clonogenic Survival. Molecular Cell 42, 23-35.

Cullen, S.P., Henry, C.M. and S. J. Martin (2011) Staying alive: defensive strategies in the Bcl-2 family playbook. Molecular Cell 44, 509-510.

Afonina, I.A., Tynan, G.A., Logue, S. E., Cullen, S.P., Bots, M., Lüthi, A. U., Reeves, E. P., McElvaney, N. G., Medema, J. P., Lavelle, E. C. and S.J. Martin (2011) Granzyme B-dependent proteolysis acts as a switch to enhance the pro-inflammatory activity of IL-1α. Molecular Cell, 44, 265-278.

Lüthi, A.U., Cullen, S.P., McNeela, E.A., Duriez, P.J., Afonina, I.S., Sheridan, C., Brumatti, G., Taylor, R.C., Kersse, K., Vandenabeele, P., Lavelle, E.C. and S. J. Martin. (2009) Suppression of IL-33 Bioactivity through Proteolysis by Apoptotic Caspases. Immunity, 31, 84-98.

Autret, A. and S.J. Martin. (2009) Emerging role for members of the Bcl-2 family in mitochondrial morphogenesis. Molecular Cell, 36, 355-363

Taylor, R. C, Cullen, S. P. and S.J. Martin. (2008) Apoptosis: demolition at the cellular level. Nature Reviews, Molecular & Cell Biology 9, 231-241.

Sheridan, C., Delivani, P., Cullen, S .P. & S.J. Martin (2008) Bax or Bak-dependent mitochondrial fission can be uncoupled from cytochrome c release. Molecular Cell 31, 570-585.

Cullen S.P., Adrain, C., Luthi, A. U., Duriez, P. J., and S.J. Martin. (2007) Human and Murine Granzyme B Exhibit Divergent Substrate Preferences. Journal of Cell Biology, 176, 435.

Delivani, P., Adrain, C., Taylor, RC., Duriez, P.J & S.J. Martin (2006) Role for CED-9 and Egl-1 as regulators of mitochondrial fission and fusion dynamics. Molecular Cell 21, 761-773.