Plant Developmental Genetics



Miricescu, A., Brazel, A.J., Beegan, J., Wellmer, F., and Graciet, E. (2023) Transcriptional analysis in barley identifies signatures of waterlogging response. Plant Direct 7:e518. (Pubmed)

Maika, J., Kraemer, B., Wellmer, F., Weidtkamp-Peters, S., Stahl, Y., and Simon, R. (2023) One Pattern Analysis (OPA) for the quantitative determination of protein interactions in plant cells. Plant Methods 19:73. (Pubmed)

O Maoileidigh, D.S., Thomson, B., and Wellmer, F. (2023) Floral induction systems for the study of early Arabidopsis flower development. Methods in Molecular Biology 2686, 285-292. (Pubmed)

Goslin, K., Finocchio, A., and Wellmer, F. (2023) Floral homeotic factors: a question of specificity. Plants 12, 1128. (Pubmed)


Goslin, K., Finocchio, A., and Wellmer, F. (2021) A Golden Gate-based plasmid library for the rapid assembly of biotin ligase constructs for proximity labelling. (bioRxiv)

Kwasniewska, K., Breathnach, C., Fitzsimons, F., Goslin, K., Thomson, B., Beegan, J., Finocchio, A., Prunet, N., O Maoileidigh, D.S., and Wellmer, F. (2021) Expression of KNUCKLES in the stem cell domain is required for its function in the control of floral meristem activity in Arabidopsis. Frontiers in Plant Science 12:704351. (Pubmed)


*Velanis, C., *Perera, P., Thomson, B., de Leau, E., Liang, S.C., Hartwig, B., Foerderer, A., Thornton, H., Arede, P., Chen, J., Webb, K.M., Gumus, S., De Jaeger, G., Page, C.A., Hancock, C.N., Spanos, C., Rappsilber, J., Voigt, P., Turck, F., Wellmer, F., and Goodrich, J. (2020) The domesticated transposase ALP2 mediates formation of a novel Polycomb protein complex by direct interaction with MSI1, a core subunit of Polycomb Repressive Complex 2 (PRC2). PLoS Genetics 16:e1008681. *equal contribution. (Pubmed)


Thomson, B. and Wellmer, F. (2019) Molecular regulation of flower development. Current Topics in Developmental Biology 131, 185-210. (Pubmed)


Xu, Y., Prunet, N., Gan, E.-S., Wang, Y., Stewart, D., Wellmer, F., Huang, J., Yamaguchi, N., Tatsumi, Y., Kojima, M., Kiba, T., Sakakibara, H., Jack, T.P., Meyerowitz, E.M., and Ito, T. (2018) SUPERMAN regulates floral whorl boundaries through control of auxin biosynthesis. EMBO Journal 37, e97499. (Pubmed)

Zheng, B., Thomson, B., and Wellmer, F. (2018) Strategies for the specific knockdown of transcription factor activities in Arabidopsis. Methods in Molecular Biology 1830, 81-92. (Pubmed)

*O Maoileidigh, D.S., *Stewart, D., Zheng, B., Coupland, G., and Wellmer, F. (2018) Floral homeotic proteins modulate the genetic program for leaf development to suppress trichome formation in flowers. Development 145, dev157784. *equal contribution (Pubmed)

Engelhorn, J., Wellmer, F., Carles, C.C. (2018) Profiling histone modifications in synchronised floral tissues for quantitative resolution of chromatin and transcriptome dynamics. Methods in Molecular Biology 1675, 271-296. (Pubmed)


Serrano-Mislata, A., Goslin, K., Zheng, B., Rae, L., Wellmer, F., Graciet, E., and Madueno, F. (2017) Regulatory interplay between LEAFY, APETALA1/CAULIFLOWER and TERMINAL FLOWER1: new insights into an old relationship. Plant Signaling & Behavior 12, e1370164. (Pubmed)

*Goslin, K., *Zheng, B., Serrano-Mislata, A., Rae, L., Ryan, P.T., Kwasniewska, K., Thomson, B., O Maoileidigh, D.S., Madueno, F., *Wellmer, F., and *Graciet, E. (2017) Transcription factor interplay between LEAFY and APETALA1/CAULIFLOWER during floral initiation. Plant Physiology 174, 1097-1109. *equal contribution (Pubmed)

Thomson, B., Graciet, E., and Wellmer, F. (2017) Inducible promoter systems for gene perturbation experiments in Arabidopsis. Methods in Molecular Biology 1629, 15-25. (Pubmed)

Thomson, B., Zheng, B., and Wellmer, F. (2017) Floral organogenesis: when knowing your ABCs is not enough. Plant Physiology 173, 56-64. (Pubmed)

Wellmer, F. (2017) Flower development. In Brian Thomas, Brian G Murray and Denis J Murphy (Editors in Chief), Encyclopedia of Applied Plant Sciences, Vol 2, Waltham, MA: Academic Press, 2017, pp. 269-274. (Link)


de Marchi, R., Sorel, M., Mooney, B., Fudal, I., Goslin, K., Kwasniewska, K., Ryan, P.T., Pfalz, M., Kroymann, J, Pollmann, S., Feechan, A., Wellmer, F., Rivas, S., and Graciet, E. (2016) The N-end rule pathway regulates pathogen responses in plants. Scientific Reports 6: 26020. (Pubmed)

Drost, H.-G., Bellstaedt, J., O Maoileidigh, D.S., Silva, A.T., Gabel, A., Weinholdt, C., Ryan, P.T., Dekkers, B.J.W., Bentsink, L., Hilhorst, H., Ligterink, W., Wellmer, F., Grosse, I., and Quint, M. (2016) Post-embryonic hourglass patterns mark ontogenetic transitions in plant development. Molecular Biology and Evolution 33, 1158-1163. (Pubmed)

Stewart, D., Graciet, E., and Wellmer, F. (2016) Molecular and regulatory mechanisms controlling floral organ development. FEBS Journal 283, 1823-1830. (Pubmed)

O Maoileidigh, D.S., Graciet, E., and Wellmer, F. (2016) Strategies for performing dynamic gene perturbation experiments in flowers. Bio-protocol 6: e1774. (PDF)


*Ryan, P.T., *O Maoileidigh, D.S., Drost, H.-G., Kwasniewska, K., Gabel, A., Grosse, I., Graciet, E., Quint, M., and Wellmer, F. (2015) Patterns of gene expression during Arabidopsis flower development from the time of initiation to maturation. BMC Genomics 16:488. *equal contribution (Pubmed)

O Maoileidigh, D.S., *Thomson, B., *Raganelli, A., Wuest, S.E., Ryan, P.T., Kwasniewska, K., Carles, C.C., Graciet, E., and Wellmer, F. (2015) Gene network analysis in Arabidopsis thaliana flower development through dynamic gene perturbations. Plant Journal 83, 344-358. *equal contribution (Pubmed)

Wellmer, F., Stewart, D., and O Maoileidigh, D.S. (2015) My favourite flowering image: floral organs with trichomes. Journal of Experimental Botany 66, 9-10. (PDF)

Town, C.D. and Wellmer, F. (2015) Genome structure and organization. In: Biochemistry and Molecular Biology of Plants. 2nd edition. B. Buchanan, W. Gruissem, R. Jones (eds.). Wiley, New York. (Link)

Yamaguchi, N., Winter, C.M., Wellmer, F., and Wagner, D. (2015) Identification of direct targets of plant transcription factors using the GR fusion technique. Methods in Molecular Biology 1284, 123-138. (Pubmed)


O Maoileidigh, D.S., Graciet, E., and Wellmer, F. (2014) Genetic control of Arabidopsis flower development. In: Advances in Botanical Research 72, F. Fornara (ed.), Academic Press (Elsevier). (Link)

Pajoro, A., Madrigal, P., Muino, J.M., Matus, T., Jin, J., Mecchia, M.A., Debernardi, J.M., Palatnik, J.F., Balazadeh, S., Arif, M., O Maoileidigh, D.S., Wellmer, F., Krajewski, P., Riechmann, J.L., Angenent, G.C., and Kaufmann, K. (2014) Dynamics of chromatin accessibility and gene regulation by MADS-domain transcription factors in flower development. Genome Biology 15, R41. (Pubmed)

Wellmer, F., Graciet, E., and Riechmann, J.L. (2014) Specification of floral organs in Arabidopsis. Journal of Experimental Botany 65, 1-9. (Pubmed)

O Maoileidigh, D.S. and Wellmer, F. (2014) A floral induction system for the study of early Arabidopsis flower development. Methods in Molecular Biology 1110, 307-314. (Pubmed)

Graciet, E., O Maoileidigh, D.S., and Wellmer, F. (2014) Next-generation sequencing applied to flower development (ChIP-Seq). Methods in Molecular Biology 1110, 413-429. (Pubmed)

Wellmer, F., Bowman, J.L., Davies, B., Ferrandiz, C., Fletcher, J.C., Franks, R.G., Graciet, E., Gregis, V., Ito, T., Jack, T.P., Jiao, Y., Kater, M.M., Ma., H., Meyerowitz, E.M., Prunet, N., and Riechmann, J.L. (2014) Flower development - open questions and future directions. Methods in Molecular Biology 1110, 103-124. (Pubmed)

Riechmann, J.L. and Wellmer, F. eds. (2014) Flower Development: Methods and Protocols. Methods in Molecular Biology Volume 1110. Humana Press, New York. (Link)

O Maoileidigh, D.S., Graciet, E., and Wellmer, F. (2014) Gene networks controlling Arabidopsis flower development. New Phytologist 201, 16-30. (Pubmed)


*O Maoileidigh, D.S., *Wuest, S.E., Rae, L., Raganelli, A., Ryan, P.T., Kwasniewska, K., Das, P., Lohan, A.J., Loftus, B., Graciet, E., and Wellmer, F. (2013) Control of reproductive floral organ identity specification in Arabidopsis by the C function regulator AGAMOUS. Plant Cell 25, 2482-2503. *equal contribution (Pubmed)


*Wuest, S.E., *O Maoileidigh, D.S., Rae, L., Kwasniewska, K., Raganelli, A., Hanczaryk, K., Lohan, A.J., Loftus, B., Graciet, E., and Wellmer, F. (2012) Molecular basis for the specification of floral organs by APETALA3 and PISTILLATA. Proc. Natl. Acad. Sci. USA 109, 13452-13457. *equal contribution (Pubmed)


Wellmer, F. and Riechmann, J.L. (2010) Gene networks controlling the initiation of flower development. Trends in Genetics 26, 519-527. (Pubmed)

Graciet, E. and Wellmer, F. (2010) The plant N-end rule pathway: structure and functions. Trends in Plant Science 15, 447-453. (Pubmed)

*Kaufmann, K., *Wellmer, F., Muino, J.M., Ferrier, T., Wuest, S.E., Kumar, V., Serrano-Mislata, A., Madueno, F., Krajewski, P., Meyerowitz, E.M., Angenent, G.C., and Riechmann, J.L. (2010) Orchestration of floral initiation by APETALA1. Science 328, 85-89. *equal contribution (Pubmed|PDF|Supplemental Data)

Wuest, S.E., Vijverberg, K., Schmidt, A., Weiss, M., Gheyselinck, J., Lohr, M., Wellmer, F., Rahnenfuhrer, J., von Mering, C, and Grossniklaus, U. (2010) Arabidopsis female gametophyte gene expression map reveals similarities between plant and animal gametes. Current Biology 20, 506-512. (Pubmed|PDF)

Graciet, E., Mesiti, F., and Wellmer, F. (2010) Structure and evolutionary conservation of the plant N-end rule pathway. Plant Journal 61, 741-751. (Pubmed|PDF)


Graciet, E., Walter, F., O Maoileidigh, D., Pollmann, S., Meyerowitz, E.M., Varshavsky, A., and Wellmer, F. (2009) The N-end rule pathway controls multiple functions during Arabidopsis shoot and leaf development. Proc. Natl. Acad. Sci. USA 106, 13618-13623. (Pubmed|PDF|Supplemental Data)

Das, P., Ito, T., Wellmer, F., Vernoux, T., Dedieu, T., Traas, J., and Meyerowitz, E.M. (2009) Floral stem cell termination involves the direct regulation of AGAMOUS by PERIANTHIA. Development 136, 1605-1611. (Pubmed)


Alves-Ferreira, M., Wellmer, F., Banhara, A., Kumar, V., Riechmann, J.L. and Meyerowitz, E.M. (2007) Global expression profiling applied to the analysis of Arabidopsis stamen development. Plant Physiology 145, 747-762. (Pubmed)

Sieber, P., Wellmer, F., Gheyselinck, J., Riechmann, J.L. and Meyerowitz, E.M. (2007) Redundancy and specialization among plant microRNAs: role of the miR164 family in developmental robustness. Development 134, 1051-1060. (Pubmed)

Carlsson, J., Lagercrantz, U., Sundstrom, J., Teixeira, R., Wellmer, F., Meyerowitz, E.M. and Glimelius, K. (2007) Microarray analysis reveals altered expression of a large number of nuclear genes in developing cytoplasmic male sterile Brassica napus flowers. Plant Journal 49, 452-462. (Pubmed)


Wellmer, F., Alves-Ferreira, M., Dubois, A., Riechmann, J.L. and Meyerowitz, E.M. (2006) Genome-wide analysis of gene expression during early Arabidopsis flower development. PLoS Genetics 2, e117. (Pubmed|PDF)


Wellmer, F. and Riechmann, J.L. (2005) Gene network analysis in plant development by genomic technologies. International Journal of Developmental Biology 49, 745-759. (Pubmed)

*Baker, C.C., *Sieber, P., Wellmer, F. and Meyerowitz, E.M. (2005) The early extra petals1 mutant uncovers a role for microRNA miR164c in regulating petal number in Arabidopsis. Current Biology 15, 303-315. *equal contribution (Pubmed)


Ito, T., Wellmer, F., Yu, H., Das, P., Ito, N., Alves-Ferreira, M., Riechmann, J.L. and Meyerowitz, E.M. (2004) The homeotic protein AGAMOUS controls microsporogenesis by regulation of SPOROCYTELESS. Nature 430, 356-360. (Pubmed)

*Wagner, D., *Wellmer, F., Dilks, K., William, D., Smith, M.R., Kumar, P.P., Riechmann, J.L., Greenland, A.J. and Meyerowitz, E.M. (2004) Floral induction in tissue culture: a system for the analysis of LEAFY-dependent gene regulation. Plant Journal 39, 273-282. *equal contribution (Pubmed)

Wellmer, F., Riechmann, J.L., Alves-Ferreira, M. and Meyerowitz, E.M. (2004) Genome-wide analysis of spatial gene expression in Arabidopsis flowers. Plant Cell 15, 1314-1326. (Pubmed)

Yu, H., Ito, T., Wellmer, F. and Meyerowitz, E.M. (2004) Repression of AGAMOUS-LIKE 24 is a crucial step in promoting flower development. Nature Genetics 36, 157-161. (Pubmed)


Rügner, A., Frohnmeyer, H., Näke, C., Wellmer, F., Kircher, S., Schäfer, E., and Harter, K. (2001) Isolation and characterization of four novel parsley proteins that interact with the transcriptional regulators CPRF1 and CPRF2. Molecular Genetics and Genomics 265, 964-976. (Pubmed)

Schäfer, E., Kircher, S., Gil, P., Harter, K., Kim, L., Wellmer, F., Kozma-Bognar, L., Adam, E., and Nagy, F. (2001) Signal Transduction in Photomorphogenesis: Intracellular Partitioning of Factors and Photoreceptors. In: Signal transduction in plants: current advances. S.K. Sopory, R. Oelmüller, and S.C. Maheshwari (eds.), Kluwer Academic Publishers, New York. (Link)

Wellmer, F., Schäfer, E., and Harter, K. (2001) The DNA binding properties of the parsley bZIP transcription factor CPRF4a are regulated by light. Journal of Biological Chemistry 276, 6274-6279. (Pubmed)


Wellmer, F., Kircher, S., Rügner, A., Frohnmeyer, H., Schäfer, E., and Harter, K. (1999) Phosphorylation of the parsley bZIP transcription factor CPRF2 is regulated by light. Journal of Biological Chemistry 249, 134-141. (Pubmed)

*Kircher, S., *Wellmer, F., Nick, P., Rügner, A., Schäfer, E., and Harter, K. (1999) Nuclear import of the parsley bZIP transcription factor CPRF2 is regulated by phytochrome photoreceptors. Journal of Cell Biology 274, 29476-29482. *equal contribution (Pubmed)


Schulenberg, B., Wellmer, F., Lill, H., Junge, W., and Engelbrecht, S. (1997) Cross-linking of the chloroplast F0F1-ATPase subunit Epsilon to Gamma without effects on activity. Epsilon and Gamma are parts of the rotor. European Journal of Biochemistry 249, 134-141. (Pubmed)