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Biomarker Analysis - BIOMARKAPD

Blood and CSF samples will be stored according to a strict protocol and standard operating procedure (SOP). Analysis of CSF research samples will take place in the Department of Immunology Laboratory, Central Pathology Laboratory, St. James’s Hospital. ELISA Testing will be performed to measure the levels of the biomarkers T-Tau, P- Tau and Aβ 42. 

Blood samples will also be analysed in The Department of Immunology Laboratory, St James Hospital   and samples will be stored and transported at the end of the study, to an appropriate lab for APOE genotyping.

A portion of each CSF and blood sample will be provided to European collaborating laboratories as part of the BIOMARKAPD project to aid in the standardisation process for CSF biomarkers across Europe and to support the development of a clinical reference laboratory at St. James's Hospital.

As part of BIOMARKAPD, some samples will also be provided to a central biobank in Luxembourg which is ISO certified to aid in the future development of biomarkers for AD across Europe.

Standard Operating Procedures (SOPs) - Guidelines for biological sample collection

For further information on contributions to the Integrated Biobank Luxembourg (IBBL) please contact Anne-Marie Miller

 


Last updated 7 January 2014 MILLERAM@tcd.ie (Email).