Dr. Sinead Murphy
Clinical Associate Professor, Clinical Medicine
Publications and Further Research Outputs
Peer-Reviewed Publications
. Murphy SJX, Lim ST, Kinsella JA, Tierney S, Egan B, Feeley TM, Murphy SM, Walsh RA, Collins DR, Coughlan T, O'Neill D, Harbison JA, Madhavan P, O'Neill SM, Colgan MP, Cox D, Moran N, Hamilton G, McCabe DJH, Increased leucocyte-platelet complex formation in recently symptomatic versus asymptomatic carotid stenosis patients and in micro-emboli negative subgroups. , Thrombosis and Haemostasis , 2019
Stephen Murphy, Soon Tjin Lim, Justin Kinsella, Sean Tierney, Bridget Egan, T Martin Feeley, Sinead Murphy, Richard Walsh, Ronan Collins, Tara Coughlan, Desmond O'Neill, Sean O'Neill, Joseph Harbison, Prakash Madhavan, Mary Paula Colgan, Dermot Cox, Niamh Moran, George Hamilton, Dominick McCabe, On-treatment platelet reactivity' under both high and low shear stress conditions and relationship with cerebral micro-embolic signals in asymptomatic and symptomatic carotid stenosis: Results from the HaEmostasis In carotid STenosis(HEIST) study, Neurology, American Academy of Neurology, Philadelphia, May 4 - May 11 2019, 92, (Supp 15), 2019
DA Olszewska, EM Fallon, GM Pastores, K Murphy, A Blanco, T Lynch, SM Murphy, Autosomal dominant gene negative frontotemporal dementia-think of SCA17, Cerebellum, 2019
. Murphy SJX, Lim ST, Kinsella JA, Murphy D, Enright HM, McCabe DJH for the HEIST study group, Platelet count and profile of reticulated platelets and red cell reticulocytes in patients with recently symptomatic versus asymptomatic carotid stenosis: Results from the HaEmostasis In carotid STenosis (HEIST) study, Journal of Neurology , 265, 2018, p1037-
Bogdanova-Mihaylova, P., Murphy, R.P.J., Alexander, M.D., McHugh, J.C., Foley, A.R., Brett, F., Murphy, S.M., Congenital myasthenic syndrome due to DPAGT1 mutations mimicking congenital myopathy in an Irish family, European Journal of Neurology, 25, (2), 2018, pe22-e23
Renaud, M., Moreira, M.-C., Monga, B.B., Rodriguez, D., Debs, R., Charles, P., Chaouch, M., Ferrat, F., Laurencin, C., Vercueil, L., Mallaret, M., M"Zahem, A., Pacha, L.A., Tazir, M., Tilikete, C., Ollagnon, E., Ochsner, F., Kuntzer, T., Jung, H.H., Beis, J.-M., Netter, J.-C., Djamshidian, A., Bower, M., Bottani, A., Walsh, R., Murphy, S., Reiley, T., Bieth, É., Roelens, F., Poll-The, B.T., Lourenço, C.M., Jardim, L.B., Straussberg, R., Landrieu, P., Roze, E., Thobois, S., Pouget, J., Guissart, C., Goizet, C., Dürr, A., Tranchant, C., Koenig, M., Anheim, M., Clinical, biomarker, and molecular delineations and genotype-Phenotype correlations of ataxia with oculomotor apraxia type 1, JAMA Neurology, 75, (4), 2018, p495-502
D'Alton M, Coughlan T, Cogan N, Greene S, McCabe DJH, McCarthy A, Murphy S, Walsh R, O'Neill D, Kennelly S, Ryan D, Collins R, Patterns of Mortality in Modern Stroke Care, Ir Med J, 111, (5), 2018, pP750
Bogdanova-Mihaylova, P., Burke, D., O"Dwyer, J.P., Bradley, D., Williams, J.A., Cronin, S.J., Smyth, S., Murphy, R.P., Murphy, S.M., Wall, C., McCabe, D.J.H., Aciclovir-induced acute kidney injury in patients with `suspected viral encephalitis" encountered on a liaison neurology service, Irish Journal of Medical Science, 2018, p1-4
Rossor, A.M., Morrow, J.M., Polke, J.M., Murphy, S.M., Houlden, H., Laura, M., Manji, H., Blake, J., Reilly, M.M., Pilot phenotype and natural history study of hereditary neuropathies caused by mutations in the HSPB1 gene, Neuromuscular Disorders, 27, (1), 2017, p50-56
Petya Bogdanova-Mihaylova, Richard A Walsh & Sinéad M Murphy, Utility of ataxia gene panel testing in Irish inherited ataxia cases, ABN, Liverpool, UK, 2017, 2017
Bogdanova-Mihaylova P, Austin N, Alexander MD, Cassidy L, Early A, Murphy RP, Murphy SM, Walsh RA., Anoctamin 10-Related Autosomal Recessive Cerebellar Ataxia: Comprehensive Clinical Phenotyping of an Irish Sibship., Movement disorders clinical practice, 4, (2), 2017, p258-262
P Bogdanova-Mihaylova, R Walsh, S Murphy, Living with Ataxia in Ireland 2016-a Nationwide Survey of 130 Irish Patients with Inherited Ataxia, Movement Disorders, International Congress of Parkinson's Disease & Movement Disorders , Vancouver, June 4-8, 32, 2017
J Panicker, M Lad, M Parkinson, M Rai, M Pandolfo, P Mihaylova-Bogdanova, RA Walsh, S Murphy, A Emmanuel, P Giunti, 'Lower urinary tract, bowel and sexual dysfunction in Friedreich’'s ataxia' , Journal of the Neurological Sciences, World Congress of Neurology, Kyoto, Japan, 2017, 2017
. Meher Lad, Michael H. Parkinson, Myriam Rai, Massimo Pandolfo, Petya Mihaylova-Bogdanova, Richard A Walsh, Sinéad M Murphy, Anton Emmanuel, Jalesh Panicker, Paola Giunti, A Survey of Lower Urinary Tract, Bowel and Sexual symptoms in a Large Cohort of Patients with Friedreich's Ataxia, Orphanet Journal of Rare Diseases , 12, (1), 2017, p158-
Petya Bogdanova-Mihaylova, Richard A Walsh & Sinéad M Murphy, Living with Ataxia in Ireland 2016 - a nationwide survey, ABN, Liverpool, UK, 2017, 2017
Bogdanova-Mihaylova P, Alexander MD, Murphy RPJ, Murphy SM., Waardenburg syndrome: a rare cause of inherited neuropathy due to SOX10 mutation., Journal of the peripheral nervous system : JPNS, 22, (3), 2017, p219-223
Stubbe, Cassandra; Bogdanova-Mihaylova, Petya; Austin, Neil; Murphy, Sinead; Walsh, Richard, NGS-based molecular diagnosis of hereditary ataxia is cost efficient: an illustrative case, QJM: An International Journal of Medicine , 109, (8), 2016, p551 - 552
P Bogdanova-Mihaylova, N Austin, MD Alexander, L Cassidy, SM Murphy, RA Walsh, autosomal recessive ataxia due to Ano10 mutations; full and novel phenotypic data in an Irish pedigree: 1071, Movement Disorders, International Congress of Parkinson's Disease & Movement Disorders , Berlin, June 19-23, 2016
. Chen YC, Auer-Grumbach M, Matsukawa S, Zitzelsberger M, Themistocleous AC, Strom TM, Samara C, Moore AW, Cho LT, Young GT, Weiss C, Schabhüttl M, Stucka R, Schmid AB, Parman Y, Graul-Neumann L, Heinritz W, Passarge E, Watson RM, Hertz JM, Moog U, Baumgartner M, Valente EM, Pereira D, Restrepo CM, Katona I, Dusl M, Stendel C, Wieland T, Stafford F, Reimann F, von Au K, Finke C, Willems PJ, Nahorski MS, Shaikh SS, Carvalho OP, Nicholas AK, Karbani G, McAleer MA, Cilio MR, McHugh JC, Murphy SM, Irvine AD, Jensen UB, Windhager R, Weis J, Bergmann C, Rautenstrauss B, Baets J, De Jonghe P, Reilly MM, Kropatsch R, Kurth I, Chrast R, Michiue T, Bennett DL, Woods CG, Senderek J, Corrigendum: Transcriptional regulator PRDM12 is essential for human pain perception, Nature Genetics, 47, (8), 2015, p962-
A. M. Rossor*, E. C. Oates*, H. K. Salter, Y. Liu, S. M. Murphy, R. Schule, M. A. Gonzales, M. Scoto, R. Phadke, C. A. Sewry, H. Houlden, A. Jordanova, I. Tournev, T. Chamova, I. Litvinenko, S. Zuchner, D. N. Herrmann , J. Blake, J. E. Sowden, G. Acsadi, M. L. Rodriguez, M. P. Menezes, N. F. Clarke, M. Auer Grumbach, S. L. Bullock, F. Muntoni, M. M. Reilly , K. N. North, Phenotypic and molecular insights into Spinal Muscular Atrophy due to mutations in BICD2, Brain , 138, (2), 2015, p293 - 310
Bogdanova-Mihaylova, Petya; Alexander, Michael; Murphy, Raymond; Murphy, Sinéad, SCN9A-associated congenital insensitivity to pain and anosmia in an Irish patient, Journal of the Peripheral Nervous System, 20, (2), 2015, p86 - 87
. Boglarka Bansagi*, Thalia Antoniadi*, Sarah Burton-Jones, Sinead M Murphy, John McHugh, Michael Alexander, Richard Wells, Joanna Davies, David Hilton-Jones, Hanns Lochmüller, Patrick Chinnery, Rita Horvath, Genotype/phenotype correlations in AARS-related neuropathy in a cohort of patients from the United Kingdom and Ireland, Journal of Neurology, 262, (8), 2015, p1899 - 1908
Ramdharry GM, Pollard A, Anderson C, Laura M, Murphy SM, Dudziec M, Dewar EL, Hutton E, Grant R, Reilly MM, A Pilot Study of Proximal Strength Training in Charcot Marie Tooth Disease, Journal of the Peripheral Nervous System , 2015
Meher Lad, Michael Parkinson, Myriam Rai, Massimo Pandolfo, Sinead Murphy, Anton Emmanuel, Jalesh Panicker, Paola Giunti, Urinary, bowel and sexual function in patients with Friedreich's ataxia, Journal of Neurology, Neurosurgery & Psychiatry , ABN, London, UK, 2015, 86, 2015, ppe4-
Stela Lefter, Orla Hardiman, Russell L. McLaughlin, Sinead M. Murphy, Michael Farrell, Aisling M. Ryan, A novel MYH7 Leu1453pro mutation resulting in Laing distal myopathy in an Irish family, Neuromuscular Disorders , 25, (2), 2015, p155 - 160
Daniela Ernst*, Sinéad M Murphy*, Karthik Sathiyanadan, Yu Wei, Alaa Othman, Matilde Laurá, Yo-Tsen Liu, Anke Penno, Julian Blake, Michael Donaghy, Henry Houlden, Mary M Reilly#,, Thorsten Hornemann , Novel HSAN1 mutation in Serine-Palmitoyltransferase resides at a putative phosphorylation site that is involved in regulating substrate specificity, Neuromolecular Medicine , 17, (1), 2015, p47 - 57
. A. M. Rossor, E. C. Oates, H. K. Salter, Y. Liu, S. M. Murphy, R. Schule,M. A. Gonzales, M. Scoto, R. Phadke, C. A. Sewry, H. Houlden, A. Jordanova, I. Tournev, T. Chamova, I. Litvinenko, S. Zuchner, D. N. Herrmann, J. Blake, J. E. Sowden, G. Acsadi, M. L. Rodriguez, M. P. Menezes, N. F. Clarke, M. Auer Grumbach, S. L. Bullock, F. Muntoni, M. M. Reilly, K. N. North, Reply to: The p.Ser107Leu in BICD2 is a mutation "hot spot" causing distal spinal muscular atrophy, Brain, 138, (11), 2015, pe392-
Goyal M, Demchuk AM, Menon BK, Eesa M, Rempel JL, Thornton J, Roy D, Jovin TG, Willinsky RA, Sapkota BL, Dowlatshahi D, Frei DF, Kamal NR, Montanera WJ, Poppe AY, Ryckborst KJ, Silver FL, Shuaib A, Tampieri D, Williams D, Bang OY, Baxter BW, Burns PA, Choe H, Heo JH, Holmstedt CA, Jankowitz B, Kelly M, Linares G, Mandzia JL, Shankar J, Sohn SI, Swartz RH, Barber PA, Coutts SB, Smith EE, Morrish WF, Weill A, Subramaniam S, Mitha AP, Wong JH, Lowerison MW, Sajobi TT, Hill MD, Randomized assessment of rapid endovascular treatment of ischemic stroke., The New England Journal of Medicine, 372, (11), 2015, p1019-30
Chen YC, Auer-Grumbach M, Matsukawa S, Zitzelsberger M, Themistocleous AC, Strom TM, Samara C, Moore AW, Cho LT, Young GT, Weiss C, Schabhüttl M, Stucka R, Schmid AB, Parman Y, Graul-Neumann L, Heinritz W, Passarge E, Watson RM, Hertz JM, Moog U, Baumgartner M, Valente EM, Pereira D, Restrepo CM, Katona I, Dusl M, Stendel C, Wieland T, Stafford F, Reimann F, von Au K, Finke C, Willems PJ, Nahorski MS, Shaikh SS, Carvalho OP, Nicholas AK, Karbani G, McAleer MA, Cilio MR, McHugh JC, Murphy SM, Irvine AD, Jensen UB, Windhager R, Weis J, Bergmann C, Rautenstrauss B, Baets J, De Jonghe P, Reilly MM, Kropatsch R, Kurth I, Chrast R, Michiue T, Bennett DL, Woods CG, Senderek J, Transcriptional regulator PRDM12 is essential for human pain perception., Nature genetics, 47, (7), 2015, p803-8
Vera Fridman, Sinéad M Murphy, The spectrum of axonopathies: From CMT2 to HSP, Neurology , 83, (7), 2014, p580 - 581
O'Donnell L, O'Neill D, Collins R, Coughlan T, McCabe D, Murphy S, Walsh R, Outcomes of Occupational Therapy Interventions within a Stroke Early Supported Discharge (ESD) Service; a 9 Month Retrospective Clinical Audit, Ir J Med Sci, Irish Gerontological Society, Galway, 10-11 Oct 2014, 183, (Suppl 7), 2014, ppS360-1
Reza Sadjadi, Mary M. Reilly, Michael E. Shy, Davide Pareyson, Matilde Laura, Sinead Murphy, Shawna M.E. Feely, Tiffany Grider, Chelsea Bacon, Giuseppe Piscosquito, Daniela Calabrese, Ted M. Burns, Psychometrics evaluation of Charcot-Marie-Tooth Neuropathy Score (CMTNSv2) second version, using Rasch analysis, Journal of the Peripheral Nervous System, 19, (3), 2014, p192 - 196
Judith Conroy, Paul McGettigan, Raymond Murphy, David Webb, Sinéad M Murphy, Blathnaid McCoy, Christine Albertyn, Dara McCreary, Cara McDonagh, Orla Walsh, SallyAnn Lynch, Sean Ennis, A novel locus for episodic ataxia - UBR4 the likely candidate, European Journal of Human Genetics , 22, (4), 2014, p505 - 510
Greene S, Cogan N, Briggs R, Coughlan T, O'Neill D, Mc Cabe D, Murphy S, Walsh R, Collins R, Neuromedical Sequelae Post-Stroke, Ir J Med Sci, Irish Gerontological Society, Galway, 10-11 Oct 2014, 183, (Suppl 7), 2014, ppS332
Anne Belton, Richard Walsh, Sinead Murphy, Dominick McCabe, Rose Galvin, Effect of a Balance Exercise Class on Activity Limitations in People with Parkinson's Disease, Irish Journal of Medical Science, Irish Gerontological Society, Galway, 2014, Suppl 7, 2014, ppS326-
Ramdharry GM, Pollard A, Anderson C, Laurá M, Murphy SM, Dudziec M, Dewar EL, Hutton E, Grant R, Reilly MM., A pilot study of proximal strength training in Charcot-Marie-Tooth disease., Journal of the peripheral nervous system : JPNS, 19, (4), 2014, p328-332
James C Stevens, Sinéad M Murphy, Indran Davagnanam, Rahul Phadke, Glenn Anderson, Suran Nethisinghe, Fion Bremner, Paola Giunti, Mary M Reilly, The ARSACS phenotype can include supranuclear gaze palsy and skin lipofuscin deposits, Journal of Neurology, Neurosurgery and Psychiatry, 84, (1), 2013, p114 - 116
C Marquz-Infante, SM Murphy, L Mathew, A Alsanousi, MP Lunn, S Brandner, T Yousry, J Blake, MM Reilly, Asymmetric sensory ganglionopathy: a case series, Muscle & Nerve, 48, (1), 2013, p145 - 150
Hereditary amyloid neuropathy. in, editor(s)C. J. Matthias, R. Bannister , Autonomic Failure: a textbook of clinical disorders of the autonomic nervous system., Oxford University Press, 2013, pp613 - [Sinéad M Murphy, Mary M Reilly.]
DNA testing in hereditary neuropathies in, editor(s)G. Said, C. Krarup , Handbook of Clinical Neurology 3rd Series Peripheral Nerve Disorders, Elsevier, 2013, pp213 - 212, [Sinéad M Murphy, Matilde Laurá, Mary M Reilly]
S M Murphy*, D Ernst*, Y Wei, M Laurà, Y-T Liu, J Polke, J Blake, J Winer, H Houlden, T Hornemann, M M Reilly, Hereditary sensory and autonomic neuropathy type 1 (HSANI) caused by a novel mutation in SPTLC2, Neurology , 80, 2013, p1 - 6
Jaffer F, Murphy SM, Scoto M, Healy E, Rossor AM, Brandner S, Phadke R, Selcen D, Jungbluth H, Muntoni F, Reilly MM, BAG3 mutations: another cause of giant axonal neuropathy., Journal of the peripheral nervous system : JPNS, 17, (2), 2012, p210-6
Rossor AM, Davidson GL, Blake J, Polke JM, Murphy SM, Houlden H, Innes A, Kalmar B, Greensmith L, Reilly MM, A novel p.Glu175X premature stop mutation in the C-terminal end of HSP27 is a cause of CMT2., Journal of the peripheral nervous system : JPNS, 17, (2), 2012, p201-5
S Murphy, A Pandraud, Y Liu, K Fawcett, J M Polke, G Davidson, M Laura, M Davis, H , Charcot-Marie-tooth disease: genetic diagnoses in a specialist clinic, Journal of Neurology, Neurosurgery and Psychiatry , ABN Annual Meeting, Brighton, 2012, 83, 2012, ppe1-
Fawcett KA, Murphy SM, Polke JM, Wray S, Burchell VS, Manji H, Quinlivan RM, Zdebik AA, Reilly MM, Houlden H, Comprehensive analysis of the TRPV4 gene in a large series of inherited neuropathies and controls., Journal of neurology, neurosurgery, and psychiatry, 83, (12), 2012, p1204-9
Sinéad M Murphy, Carly Siskind, Richard Ovens, James Polke, Matilde Laura, Henry Houlden, Raymond PJ Murphy, Michael E Shy, Mary M Reilly, X-inactivation in females with X-linked Charcot-Marie-Tooth disease, Neuromuscular Disorders , 22, 2012, p617 - 621
Pitceathly RD, Murphy SM, Cottenie E, Chalasani A, Sweeney MG, Woodward C, Mudanohwo EE, Hargreaves I, Heales S, Land J, Holton JL, Houlden H, Blake J, Champion M, Flinter F, Robb SA, Page R, Rose M, Palace J, Crowe C, Longman C, Lunn MP, Rahman S, Reilly MM, Hanna MG., Genetic dysfunction of MT-ATP6 causes axonal Charcot-Marie-Tooth disease., Neurology, 79, (11), 2012, p1145-1154
Sinéad M Murphy, Gabrielle L Davidson, Sebastian Brandner, Henry Houlden, Mary M Reilly, Mutation in FAM134B causing severe hereditary sensory neuropathy, Journal of Neurology, Neurosurgery and Psychiatry , 83, (1), 2012, p119 - 120
PJ Arthur-Farraj, SM Murphy, M Laura, MP Lunn, H Manji, J Blake, G Ramdharry, Z Fox, MM Reilly, Hand weakness in CMT1X. , Neuromuscular Disorders , 22, 2012, p622 - 626
Davidson G, Murphy S, Polke J, Laura M, Salih M, Muntoni F, Blake J, Brandner S, Davies N, Horvath R, Price S, Donaghy M, Roberts M, Foulds N, Ramdharry G, Soler D, Lunn M, Manji H, Davis M, Houlden H, Reilly M, Frequency of mutations in the genes associated with hereditary sensory and autonomic neuropathy in a UK cohort., Journal of neurology, 259, (8), 2012, p1673-85
Rossor AM, Murphy S, Reilly MM, Knee bobbing in Charcot-Marie-Tooth disease., Practical neurology, 12, (3), 2012, p182-3
Sinéad M Murphy, Usman Khan, Constantine Alifrangis, Steven Hazell, David Hrouda, Julian Blake, Joanna Ball, Carolyn Gabriel, Pierre Markarian, Jeremy Rees, Abid Karim, Michael J Seckl, Michael P Lunn, Mary M Reilly, Anti Ma2-associated myeloradiculopathy: expanding the phenotype of anti-Ma2 associated paraneoplastic syndromes, Journal of Neurology, Neurosurgery and Psychiatry , 83, (2), 2012, p232 - 233
Sinéad M Murphy, The genetics of Charcot-Marie-Tooth Disease., CML Neurology, 28, (1), 2012, p1 - 14
Murphy SM, Laura M, Fawcett K, Pandraud A, Liu YT, Davidson GL, Rossor AM, Polke JM, Castleman V, Manji H, Lunn MP, Bull K, Ramdharry G, Davis M, Blake JC, Houlden H, Reilly MM, Charcot-Marie-Tooth disease: frequency of genetic subtypes and guidelines for genetic testing., Journal of neurology, neurosurgery, and psychiatry, 83, (7), 2012, p706-10
Murphy SM, Puwanant A, Griggs RC, Unintended effects of orphan product designation for rare neurological diseases., Annals of neurology, 72, (4), 2012, p481-90
Sinéad M Murphy, A painful neuropathy., Irish Neuromuscular Association meeting, Ireland, May 2011, 2011
M Laura, S Murphy, A Rossor, A Hiscock, M Main, ME Shy, F Muntoni, MM Reilly, Charcot-Marie-Tooth disease and related disorders: a natural history study, Neuromuscular Disorders , UK Neuromuscular Translational Research Conference , London, 2011, 21, (Suppl 1), 2011, ppS17-
Reilly MM, Murphy SM, Laurá M, Charcot-Marie-Tooth disease., Journal of the peripheral nervous system : JPNS, 16, (1), 2011, p1-14
Sinead M Murphy, Charcot-Marie-tooth disease: genetic diagnoses in a specialist clinic, Association of British Neurologists, Brighton, 2011, 2011
Smith LJ, Murphy SM, Holmes P, Reilly MM, Reiniger L, Thom M, Lunn MP, A painful right leg., BMJ (Clinical research ed.), 342, 2011, pd1009
Pandraud A, Murphy S, Laura M, Reilly MM, Houlden H, Genetic modifying factors for the common form of CMT1A due to the chromosome 17 duplication and other causes of CMT1 in non-CMT1A patients. , Neuromuscular Disorders, UK Neuromuscular Translational Research Conference, London, 2011, 21, (Suppl 1), 2011, ppS18-
Murphy SM, Laurá M, Blake J, Polke J, Bremner F, Reilly MM, Conduction block and tonic pupils in Charcot-Marie-Tooth disease caused by a myelin protein zero p.Ile112Thr mutation., Neuromuscular disorders : NMD, 21, (3), 2011, p223-6
Sinéad M Murphy, Matilde Laurá, Mary M Reilly., 'Hereditary Neuropathies', EPub www.ebrainjnc.com Module 014_006, 2011eBrain session , 2011, -
Siskind CE, Murphy SM, Ovens R, Polke J, Reilly MM, Shy ME, Phenotype expression in women with CMT1X., Journal of the peripheral nervous system : JPNS, 16, (2), 2011, p102-7
Sinéad M Murphy, X-inactivation in females with CMTX1, Irish Neurological Association (INA) , Ireland, May 2011, 2011
Sinéad M Murphy, SPTLC2 case presentation. , British Peripheral Nerve Society, Kings Hospital, London, 21 October 2011, 2011
Sinéad M Murphy, Mary M Reilly. , Amyloid neuropathies., Advances in Clinical Neuroscience and Rehabilitation, 11, (1), 2011, p16 - 19
S M Murphy, D N Herrmann, M P McDermott, S S Scherer, M E Shy, M M Reilly, D Pareyson. , Reliability of the CMT Neuropathy Score (second version) in Charcot-Marie-Tooth , Journal of Peripheral Nervous System, International CMT Consortium, Potomac,, MD, July 2011, 16, (Suppl 3), 2011, ppS93-
Sinead M Murphy, Investigation of apraxia of speech and linguistic dysprosody following acute ischaemic hemispheral stroke, University of Dublin, Trinity College Dublin, 2011
Murphy SM, Polke J, Manji H, Blake J, Reiniger L, Sweeney M, Houlden H, Brandner S, Reilly MM, A novel mutation in the nerve-specific 5'UTR of the GJB1 gene causes X-linked Charcot-Marie-Tooth disease., Journal of the peripheral nervous system : JPNS, 16, (1), 2011, p65-70
Yo-Tsen Liu, Sinéad M Murphy, Henry Houlden, Mary M Reilly, Neurofilament light chain polypeptide gene (NEFL) mutations in autosomal dominant or sporadic Charcot-Marie-Tooth disease, Neuromuscular Disorders , UK Neuromuscular Translational Research Conference, London, 2011, 21, (Supll 1), 2011, ppS17-
Murphy SM, Herrmann DN, McDermott MP, Scherer SS, Shy ME, Reilly MM, Pareyson D, Reliability of the CMT neuropathy score (second version) in Charcot-Marie-Tooth disease., Journal of the peripheral nervous system : JPNS, 16, (3), 2011, p191-8
Shiv Saidha, Sinead Murphy, Peter McCarthy, Philip Mayne, Michael Hennessy. , L-2-hydroxyglutaric aciduria diagnosed in an adult presenting with acute deterioration. , Journal of Neurology, 257, (1), 2010, p146 - 148
Sinead Murphy, Mutations in FAM134B cause hereditary sensory and autonomic neuropathy II, Irish Neurological Association, Belfast, 2010, 2010
Ryan D, Murphy SM, Hennessey MJ, Bilateral posterior cerebral artery infarction., BMJ case reports, 2010, 2010
Shiv Saidha, Sinead Murphy, Aoife Ronayne, Peter McCarthy, Michael Hennessy, Timothy Counihan., Treatment of anti-glutamic acid decarboxylase antibody associated limbic encephalitis with mycophenolate mofetil., Journal of Neurology, 257, (6), 2010, p1035 - 1038
U Khan, S Murphy, M Lunn, D Hrouda, M Seckl, J Ball, C Alifrangis, C Gabriel, S Hazel, M M Reilly, Unusual surgery for progressive finger-drop, Journal of Neurology, Neurosurgery and Psychiatry , ABN, 2010, 81, 2010, ppe64-
Cerebrovascular Disease in, editor(s)T.E. Andreoli, I.J. Benjamin, R.C. Griggs, E.J. Wing , Andreoli and Carpenter's Cecil Essentials of Medicine., Philadelphia, Saunders Elsevier, 2010, pp1123 - 1135, [Sinéad M Murphy, Timothy J Counihan.]
Cortical Syndromes. in, editor(s)T.E. Andreoli, I.J. Benjamin, R.C. Griggs, E.J. Wing , Andreoli and Carpenter's Cecil Essentials of Medicine. , Philadelphia, Saunders Elsevier, 2010, pp1068 - 1071, [Sinéad M Murphy, Timothy J Counihan.]
Sinéad M Murphy, ARSACS case presentation. , British Peripheral Nerve Society, October 2009, 2009
S Murphy, G Gorman, C Beetz, P Byrne, M Dytko, P McMonagle, K Kinsella, M Farrell, M Hutchinson, Dementia in SPG4 hereditary spastic paraplegia: clinical, genetic and neuropathological evidence, Neurology , 73, 2009, p378 - 384
Smyth A, Murphy SM, Counihan TJ, An unusual cause of cavernous sinus syndrome., BMJ case reports, 2009, 2009
Sinead Madeleine Murphy, Michael A Farrell, Michael J Hennessy, Postpartum relapsing sensory neuritis responsive to intravenous immunoglobulin, Journal of Neurology, 256, (12), 2009, p2085 - 2086
Treatment of the epilepsy patient with concomitant medical conditions in, editor(s)J.A. French, N Delanty , Therapeutic Strategies in Epilepsy, Oxford, Clinical Publishing, 2009, pp229 - 249, [Sinéad M Murphy, Norman Delanty]
SM Murphy, D McIntyre, B McAdam, JT Moroney, Transthoracic echocardiography is not useful in the routine investigation of ischaemic stroke or TIA, Irish Medical Journal , 101, (5), 2008, p106 - 106
Sinead Murphy, Dementia in SPG4 hereditary spastic paraplegia: clinical, genetic and neuropathological evidence, Irish Institute of Clinical Neuroscience (IICN) Registrar's Prize meeting , 2008, 2008
SM Murphy, A Rogers, M Hutchinson, N Tubridy, Big costs, little evidence: is there any alternative? , European Journal of Neurology, EFNS, Madrid, Spain, 2008, 15, (Suppl 3), 2008, pp357-
SM Murphy, A Rogers, M Hutchinson, N Tubridy, Counting the cost of complementary and alternative therapies in an Irish neurological clinic, European Journal of Neurology , 15, (12), 2008, p1380 - 1383
M. O'Brien, S. Murphy, M. Hutchinson, M. Farrell, N. Tubridy, Acute visual loss: Clinically blinded by atypical lymphoma, Journal of Neurology, ENS, Nice, France, 2008, 255, (Suppl 2), 2008, pp41-
Sinead M Murphy, John Thornton, Joan T Moroney., Spontaneous intra-luminal carotid thrombus in association with multiple myeloma., BloodMed on-line 1/7/07, 2007
Sinead M Murphy, John P O'Dwyer, Philip Murphy, Joan T Moroney, Cerebral ischaemia and intracerebral haemorrhage in the hypereosinophilic syndrome., BloodMed on-line 15/6/07, 2007
S Murphy, C Doherty, J Moroney, Infarct volume and apraxia of speech in acute ischaemic hemispheral stroke, Journal of Neurology, ENS, Rhodes, Greece, 2007, 254, (Suppl 3), 2007, pp34-
Sinéad M Murphy, Infarct volume and apraxia of speech in acute ischaemic hemispheral stroke. , European Neurological Society (ENS) , June 2007, 2007
Sinead Murphy, Complementary medicine in neurology: little evidence, huge costs, so why is everyone doing it? , Royal Academy of Medicine of Ireland (RAMI) / IICN meeting , 2007, 2007
Sinéad M Murphy, Cerebral ischaemia and intracerebral haemorrhage in association with the hypereosinophilic syndrome (HES)., RAMI / IICN Diaspora Meeting , October 2006, 2006
S Murphy, M Keogan, M Farrell, J Moroney, Sneddon's syndrome, marantic endocarditis and lung cancer: a paraneoplastic phenomenon, Journal of Neurology, ENS, Lausanne, Switzerland, 2006, 253, (Suppl 2), 2006, pp120-
Sinéad M Murphy, Infarct volume and apraxia of speech in acute ischaemic hemispheral stroke., RAMI / IICN Diaspora Meeting , October 2006, 2006
Sinéad M Murphy, Apraxia of speech, orofacial apraxia, and linguistic dysprosody after acute ischaemic stroke: challenging traditional thinking., ENS, June 2006, 2006
S Murphy, B McNamara, How well is peripheral neuropathy investigated? An audit from a regional neurophysiology department, Irish Journal of Medical Science , 175, (1), 2006, p54 - 56
Sinéad M Murphy, Cerebral ischaemia and intracerebral haemorrhage in association with the hypereosinophilic syndrome., Association of British Neurologists (ABN) , October 2006, 2006
Sinéad M Murphy, Apraxia of Speech and Linguistic Dysprosody following Acute Ischaemic Stroke. Challenging Traditional Teaching. , November 2005, RAMI Registrar's Prize meeting, 2005
Sinéad M Murphy, Prospective Study of Speech Recovery in Acute Ischaemic Stroke: Preliminary findings in 10 patients., INA, June 2005, 2005
A McKeon, S Murphy, B McNamara, DQ Ryder, R Galvin, Isolated hypoglossal nerve palsy due to compression by a dissecting vertebral artery., European Journal of Neurology , 53, (3), 2005, p162 - 164
Sinéad M Murphy, Paraneoplastic disease masquerading as Sneddon's Syndrome., RAMI Registrar's Prize Meeting., 2005, 2005
Sinéad M Murphy, How well is peripheral neuropathy investigated? An audit from a regional neurophysiology department., INA, June 2004, 2004
Non-Peer-Reviewed Publications
Stephen Murphy, Soon Tjin Lim, Justin Kinsella, Helen Enright, Dymphna Murphy, Sean Tierney, Bridget Egan, Martin Feeley, Sinead Murphy, Richard Walsh, Ronan Collins, Tara Coughlan, Desmond O’Neill, Joseph Harbison, Prakash Madhavan, Sean O’Neill, Mary Pat Colgan, Dermot Cox, Niamh Moran, George Hamilton, Dominick McCabe, 'Profile of Reticulated Platelets and Red Cell Reticulocytes in Patients With Recently Symptomatic versus Asymptomatic Carotid Stenosis' , Stroke, International Stroke Conference, Los Angeles, 2018, 2018
Petya Bogdanova-Mihaylova, Sinead M Murphy, Familial amyloid polyneuropathy, Hospital Doctor of Ireland, 24, (9), 2018, p27 - 30
Kinley Roberts, Sinéad Murphy, Multiple sclerosis, Forum, 34, (1), 2017
Petya Bogdanova-Mihaylova, Sinéad M Murphy & Richard A Walsh, "It's raining men": Tallaght SPG7 related spastic ataxia cases, INA, Dublin, 2017, 2017
Petya Bogdanova-Mihaylova, Neil Austin, Michael D Alexander, Lorraine Cassidy, Raymond P Murphy, Richard A Walsh, Sinéad M Murphy, DDHD2-associated autosomal recessive spastic ataxia in an Irish family, ABN, Liverpool, UK, 2017, 2017
Kinley Roberts, Linda Harrington, Sinéad M Murphy, In the clinic of a newly appointed neurologist: the first 1500 patients, ABN, Liverpool, UK, 2017, 2017
Roberts K, Harrington L, Murphy S, An audit of headache referrals to a consultant neurologist over a 2-year period at Tallaght Hospital, INA, Dublin, 2017, 2017
Petya Bogdanova-Mihaylova, Sinéad M Murphy & Richard A Walsh, SPG7-related ataxia in the Irish National Ataxia Clinic cohort, ABN, Liverpool, UK, 2017, 2017
Petya Bogdanova-Mihaylova, Raymond PJ Murphy, Richard A Walsh, Sinéad M Murphy , Underlying genetic cause in progressive cerebellar ataxias: prospective evaluation of an Irish cohort, ABN, Brighton, UK, 2016, 2016
Patricia McNamara, Petya Bogdanova-Mihaylova, Sarah Burton-Jones, Michael Alexander, Michael Hennessy, Sinead M Murphy, New Pathogenic Mutation in SLC12A6 gene in Twins with Hereditary Motor and Sensory Neuropathy with Agenesis of the Corpus Callosum, INA, Galway, 2015, 2015
McGuigan C, Ryan A, Sweeney B, Murphy S, McCabe D, Kinirons P, Murphy K, Hutchinson M, Hanna J. , Natalizumab for relapsing-remitting multiple sclerosis: interim data from the Ireland Tysabri Observational Program (iTOP). , Mult Scler, 23, (11), 2015, pp762-763. EP1462.
Petya Bogdanova-Mihaylova, Raymond PJ Murphy, Sinéad M Murphy, Utility of muscle MRI in diagnosing unsuspected congenital myasthenic syndromes, INA, Limerick, 2015, 2015
Muhammad Shakeel Majeed, Michael Alexander, Richard Walsh, Dominick McCabe, Sinéad M Murphy, Developing a seizure pathway: Evaluating the patient journey, INA, Belfast, 2014, 2014
Layan Akijian, Sindy Augustine, Dominick McCabe, Michael Alexander, Sinéad M Murphy, Periodic paralysis, a phenotypic diagnosis, INA, Belfast, 2014, 2014
Layan Akijian, Noel Fitzpatrick, John Donaghy, Sinéad M Murphy, Neurology Clinical Focus: Multiple sclerosis, Hospital Doctor of Ireland, 2014
Petya Bogdanova-Mihaylova, Christelle Oliver-Dussault, Peter Moloney, Sinéad M Murphy, Multiple sclerosis, Hospital Doctor of Ireland, 2013
McNicholas N, McAlister S, McCabe DJH, Walsh RA, Murphy SM, Treatment Practices in the management of Chronic Inflammatory Polyradiculoneuropathy (CIDP) in a Tertiary Referral Centre, INA, Dublin, 2013, 2013
Sinéad M Murphy, Carly Siskind, Richard Ovens, James Polke, Matilde Laura, Henry Houlden, Raymond PJ Murphy, Michael E Shy, Mary M Reilly, X-inactivation pattern in females with CMTX1, Neuromuscular Disorders, UK Neuromuscular Translational Research Conference, London, 2011, 21, (Suppl 1), 2011, ppS18-
Ramdharry GM, Pollard AJ, Anderson CA, Laura M, Murphy SM, Hutton EJ, Marsden JF, Reilly MM, Strengthening hip flexors to improve walking distance in people with Charcot-Marie-Tooth disease, Journal of the Peripheral Nervous System , Meeting of the Peripheral Nerve Society, Potomac, US, 2011, 16, (Suppl 3), 2011, ppS115-
Katherine Fawcett, Sinéad Murphy, James Polke, Mary Reilly, Henry Houlden, TRPV4 mutations and functional characterization in a cohort of patients with hereditary neuropathy, Neuromuscular Disorders, UK Neuromuscular Translational Research Conference, London, 2011, 21, (Suppl 1), 2011, ppS16-
Sinéad M Murphy, Gabrielle L Davidson, Matilde Laura, Mustafa Salih, Francesco Muntoni, Michael Lunn, Julian Blake, Sebastian Brandner, James Polke, Mary Davies, Henry Houlden, Mary M Reilly, Genetic mutation frequency in patients with Hereditary Sensory and Autonomic Neuropathies (HSAN). , Neuromuscular Disorders, UK Neuromuscular Translational Research Conference, London, 2011, 21, (Suppl 1), 2011, ppS117-
Arthur-Farraj PJ, Murphy SM, Fox Z, Reilly MM, Overwork weakness in CMT1X, does it exist?, International CMT Consortium, Potomac, US, 2011, 2011
Sinéad M Murphy, James Stevens, Indran Davagnanam, Rahul Phadke, Fion Bremner, Paola Giunti, Mary M Reilly, ARSACS: a common cause of neuropathy with spasticity and ataxia, INA, Sligo, 2011, 2011
S M Murphy, U Khan, C Alifrangis, S Hazel, D Hrouda, J Blake, J Ball, C Gabriel, J Rees, M Seckl, M P Lunn, M M Reilly, Anti-Ma2 associated myelo-radiculopathy, Journal of Peripheral Nervous System, Joint meeting of the Italian Peripheral Nerve Study Group and the British Peripheral Nerve Society, Trieste, Italy, 2010, 15, (Suppl 1), 2010, pp24-
Shiv Saidha, Sinéad Murphy, Aoife Ronayne, Peter McCarthy, Michael Hennessy, Timothy Counihan, Treatment of anti-glutamic acid decarboxylase antibody associated limbic encephalitis with mycophenolate mofetil, Neurology, AAN, Toronto, Canada, 2010, 74, (Suppl 2), 2010, ppA177-
G Davidson, S M Murphy, J M Polke, M B Davis, M M Reilly, H Houlden, Genes for the hereditary sensory and autonomic neuropathies: frequency in a UK series and genotype-phenotype correlations, Neuromuscular Disorders, UK Neuromuscular Translational Research Conference, 2010, 20, (Suppl 1), 2010, ppS22-
S Murphy, S Brandner, J Polke, H Manji, H Houlden, M M Reilly., A novel mutation in the nerve-specific 5′-UTR of the Cx32 gene causing CMTX1, Journal of Neurology, Neurosurgery and Psychiatry, ABN, 2010, 81, 2010, ppe50-
Sinéad M Murphy, Complementary and alternative therapy use in multiple sclerosis: Counting the cost., Multiple Sclerosis, ECTRIMS with ACTRIMS and LACTRIMS, Montreal, Canada, 2008, 14, (Suppl 1), 2008, ppS158-
SM Murphy, JP O'Dwyer, P Murphy, JT Moroney, Cerebral ischaemia and intracerebral haemorrhage in association with the hypereosinophilic syndrome, Journal of Neurology Neurosurgery & Psychiatry , ABN, London, 2006, 78, (2), 2007, pp210-
S Murphy, C Doherty, J Moroney, Apraxia of speech, orofacial apraxia, and linguistic dysprosody after acute ischaemic stroke: challenging traditional thinking, Journal of Neurology, ENS, Lausanne, Switzerland, 2006, 253, (Suppl 2), 2006, pp21-
SM Murphy, J Thornton, P Brennan, JT Moroney, Recurrent stroke due to intra-luminal carotid thrombus in a patient with active multiple myeloma, International Congress of Fibrinolysis and Proteolysis, San Diego, US, 2006, 2006
S Murphy, C Doherty, JT Moroney, Prospective Study of Speech and Language Deficits in Acute Ischaemic Stroke: Preliminary findings in 10 patients, Journal of Neurology, Neurosurgery and Psychiatry, ABN, Torquay, UK, 2005, 77, (1), 2006, pp126-
S Murphy, B McNamara, D O'Mahony, How well is peripheral neuropathy investigated? An audit from a regional neurophysiology department, Irish Journal of Medical Science, Irish Gerontology Society, 2004, 173, 2004, pp11-
S Murphy, B Sweeney., Current Therapies in Multiple Sclerosis and Future Options. , Irish Medical Times , 38, (15), 2004, p28 - 30
S Murphy, B Sweeney, Review of recent articles on the topic of Neurology., Hospital Doctor of Ireland, 1, 2004, p49 - 53
Recognition
Representations
Journal reviewer: Neurology, Muscle & Nerve, BMJ Case Reports, Irish Journal of Medical Science, Journal of the Neurological Sciences, Journal of Neurosciences in Rural Practice
Contribution to public awareness events, e.g. Huntington's Disease awareness week video, national radio interview on rare genetic diseases
Member of Irish Institute of Clinical Neuroscience (IICN), attend meetings in this capacity
National Centre for Pharmacoeconomics (NCPE) Advising on ocrelizumab for primary progressive MS (2018) and patisiran for familial TTR-associated amyloidosis (2019).
Judging poster presentations at INA annual meetings
Chairing platform sessions at European Neurological Society (ENS)
Member of Tallaght Vasculitis and Allergy Group, attend MDT meetings and give neurology input to complex cases
Updated and edited Neurology chapters of TUH Medicines Guide
Examiner for MRCPI examinations
Professional Reviewer for NIHR (National Institute for Health Research)
Awards and Honours
Travel fellowship, Peripheral Nerve Society
Harold Millar prize for best presentation, Irish Neurological Association
Travel grant, Dept. of Molecular Neuroscience, UCL Institute of Neurology, Queen Square
Dr Richard Steevens' Scholarship
Bursary EFNS (European Federation of Neurological Sciences)
Travel grant, ENS (European Neurological Society)
RAMI (Royal Academy of Medicine of Ireland) / IICN (Irish Institute of Clinical Neurosciences) Diaspora Registrar's Prize in Neurology - Research 1st prize
RAMI / IICN Diaspora Registrar's Prize in Neurology - Case Report 2nd prize
Postgraduate Certificate in Research Methods, Dept. of Statistics, UCD
TCD Entrance Exhibition Award
The Isabella Mulvaney Exhibition
Ethel M Glorney Trust Prize
The Applied Maths prize
The Jellicoe scholarship
The Trench scholarship
Memberships
FRCPI (Fellow of the Royal College of Physicians of Ireland)
MRCPI (Member of the Royal College of Physicians of Ireland)
IICN: Irish Institute of Clinical Neuroscience
Neuromuscular Group of RRNMF, an online forum of neuromuscular neurologists to discuss complex clinical cases, share information, neuromuscular grand rounds etc
Tallaght Vasculitis and Allergy Group (TVAG)
Peripheral Nerve Society: and member of subgroups Inflammatory Neuropathy Consortium and CMT and related neuropathy Consortium