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Dr. Dara Meldrum
Senior Research Fellow, Clinical Medicine

Publications and Further Research Outputs

Peer-Reviewed Publications

Murray D, Viani L, Garvan J, Murphy A, Vance R, Simoes-Franklin C, Smith J, Meldrum D., Balance, gait and dizziness in adult cochlear implant users: A cross sectional study., Cochlear implants international, 2019, p1-7 Journal Article, 2019 DOI

Tattersall, R and Murray, D and Heverin, M and Rooney, J and Tobin, K and Vance, R and Hardiman, O and Meldrum, D, Respiratory measurements and airway clearance device prescription over one year in amyotrophic lateral sclerosis, Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 2019, p1 - 8 Journal Article, 2019

Meldrum, D., Jahn, K., Gaze stabilisation exercises in vestibular rehabilitation: review of the evidence and recent clinical advances, Journal of Neurology, 266, 2019, p11-18 Journal Article, 2019

Jahn, K., Lopez, C., Zwergal, A., Zur, O., Cakrt, O., Kellerer, S., Kerkeni, H., Tjernström, F., Meldrum, D., Vestibular rehabilitation therapy in Europe: chances and challenges, Journal of Neurology, 266, 2019, p9-10 Journal Article, 2019

Seager A, French H, Meldrum D., Measurement properties of instruments for assessment of cervical spine function in infants with torticollis: a systematic review., European journal of pediatrics, 178, (5), 2019, p657-671 Journal Article, 2019 DOI

Keating, L., Treanor, C., Sugrue, J., Meldrum, D., Bolger, C., Doody, C., A randomised controlled trial of multimodal physiotherapy versus advice for recent onset, painful cervical radiculopathy - The PACeR trial protocol, BMC Musculoskeletal Disorders, 20, (1), 2019 Journal Article, 2019

Mahon, J. and Malone, A. and Kiernan, D. and Meldrum, D., Reliability of 3D upper limb motion analysis in children with obstetric brachial plexus palsy, Physiological Measurement, 38, (3), 2017, p524-538 Journal Article, 2017

Murray, D. and Hardiman, O. and Campion, A. and Vance, R. and Horgan, F. and Meldrum, D., The effects of a home-based arm ergometry exercise programme on physical fitness, fatigue and activity in Polio survivors: A randomised controlled trial, Clinical Rehabilitation, 31, (7), 2017, p913-925 Journal Article, 2017 DOI

Murray, D.A. and Meldrum, D. and Lennon, O., Can vestibular rehabilitation exercises help patients with concussion? A systematic review of efficacy, prescription and progression patterns, British Journal of Sports Medicine, 51, (5), 2017, p442-451 Journal Article, 2017

Giblin, S. and Meldrum, D. and McGroarty, M. and O{', Bone length calibration can significantly improve the measurement accuracy of knee flexion angle when using a marker-less system to capture the motion of countermovement jump, 3rd IEEE EMBS International Conference on Biomedical and Health Informatics, BHI 2016, 2016, p392-397 Journal Article, 2016

Meldrum, D. and Herdman, S. and Vance, R. and Murray, D. and Malone, K. and Duffy, D. and Glennon, A. and McConn-Walsh, R., Effectiveness of Conventional Versus Virtual Reality-Based Balance Exercises in Vestibular Rehabilitation for Unilateral Peripheral Vestibular Loss: Results of a Randomized Controlled Trial, Archives of Physical Medicine and Rehabilitation, 96, (7), 2015, p1319-1328 Journal Article, 2015

French, H.P. and Huang, X. and Cummiskey, A. and Meldrum, D. and Malone, A., Normalisation method can affect gluteus medius electromyography results during weight bearing exercises in people with hip osteoarthritis (OA): A case control study, Gait and Posture, 41, (2), 2015, p470-475 Journal Article, 2015

Malone, A. and Meldrum, D. and Bolger, C., Three-dimensional gait analysis outcomes at 1~year following decompressive surgery for cervical spondylotic myelopathy, European Spine Journal, 24, (1), 2014, p48-56 Journal Article, 2014

Murray, D, Hardiman, O, Meldrum, D, Assessment of subjective and motor fatigue in Polio survivors, attending a Postpolio clinic, comparison with healthy controls and an exploration of clinical correlates, PHYSIOTHERAPY THEORY AND PRACTICE, 30, (4), 2014, p229-235 Journal Article, 2014 DOI

Meldrum, D. and Shouldice, C. and Conroy, R. and Jones, K. and Forward, M., Test-retest reliability of three dimensional gait analysis: Including a novel approach to visualising agreement of gait cycle waveforms with Bland and Altman plots, Gait and Posture, 39, (1), 2014, p265-271 Journal Article, 2014

Malone, A. and Meldrum, D. and Gleeson, J. and Bolger, C., Electromyographic characteristics of gait impairment in cervical spondylotic myelopathy, European Spine Journal, 22, (11), 2013, p2538-2544 Journal Article, 2013

Malone, A. and Meldrum, D. and Bolger, C., Gait impairment in cervical spondylotic myelopathy: Comparison with age- and gender-matched healthy controls, European Spine Journal, 21, (12), 2012, p2456-2466 Journal Article, 2012

Dara, M. and Susan, H. and Roisin, M. and Deirdre, M. and Douglas, D. and Kareena, M. and Helen, F. and Stephen, H. and Ronan, C. and Rory, M.-W., Effectiveness of conventional versus virtual reality based vestibular rehabilitation in the treatment of dizziness, gait and balance impairment in adults with unilateral peripheral vestibular loss: A randomised controlled trial, BMC Ear, Nose and Throat Disorders, 12, (1), 2012 Journal Article, 2012

Meldrum, D. and Glennon, A. and Herdman, S. and Murray, D. and McConn-Walsh, R., Virtual reality rehabilitation of balance: Assessment of the usability of the Nintendo Wii?Fit Plus, Disability and Rehabilitation: Assistive Technology, 7, (3), 2012, p205-210 Journal Article, 2012

Murray D1, Meldrum D, Moloney R, Campion A, Horgan F, Hardiman O., The effects of a home-based arm ergometry exercise programme on physical fitness, fatigue and activity in polio survivors: Protocol for a randomised controlled trial, BMC Neurology, 12, 2012, p157- Journal Article, 2012 DOI TARA - Full Text

Malone, A. and Meldrum, D. and Gleeson, J. and Bolger, C., Reliability of surface electromyography timing parameters in gait in cervical spondylotic myelopathy, Journal of Electromyography and Kinesiology, 21, (6), 2011, p1004-1010 Journal Article, 2011

Clarke, M.N. and Ni Mhuircheartaigh, D.A. and Walsh, G.M. and Walsh, J.M. and Meldrum, D., Intra-tester and inter-tester reliability of the MicroFET 3 hand-held dynamometer, Physiotherapy Practice and Research, 32, (1), 2011, p13-18 Journal Article, 2011 DOI

McDermott, A. and Bolger, C. and Keating, L. and McEvoy, L. and Meldrum, D., Reliability of three-dimensional gait analysis in cervical spondylotic myelopathy, Gait and Posture, 32, (4), 2010, p552-558 Journal Article, 2010

Meldrum, D. and Lydon, A.-M. and Loughnane, M. and Geary, F. and Shanley, L. and Sayers, K. and Shinnick, E. and Filan, D., Assessment of undergraduate physiotherapist clinical performance: investigation of educator inter-rater reliability, Physiotherapy, 94, (3), 2008, p212-219 Journal Article, 2008

Meldrum D, Cahalane E, Conroy R, Fitzgerald D, Hardiman O, Erratum: Maximum voluntary isometric contraction: Reference values and clinical application (Amyotrophic Lateral Sclerosis (2007) vol. 8 (47-55)), Amyotrophic Lateral Sclerosis, 9, (1), 2008, p63- Journal Article, 2008 DOI URL

Meldrum, D. and Cahalane, E. and Conroy, R. and Guthrie, R. and Hardiman, O., Quantitative assessment of motor fatigue: Normative values and comparison with prior-polio patients, Amyotrophic Lateral Sclerosis, 8, (3), 2007, p170-176 Journal Article, 2007

Meldrum D, Cahalane E, Conroy R, Fitzgerald D, Hardiman O, Maximum voluntary isometric contraction: Reference values and clinical application, Amyotrophic Lateral Sclerosis, 8, (1), 2007, p47 - 55 Journal Article, 2007 DOI URL

Meldrum D, Pittock S.J, Hardiman O, Ni Dhuill C, O'Regan M, Moroney J.T, Recovery of the upper limb post ischaemic stroke and the predictive value of the Orpington Prognostic Score, Clinical Rehabilitation, 18, (6), 2004, p694 - 702 Journal Article, 2004 DOI URL

Meldrum, D. and Walsh, R.M., Vestibular and balance rehabilitation, Physical Management in Neurological Rehabilitation, 2004, p413-430 Journal Article, 2004

Pittock, S.J. and Meldrum, D. and Hardiman, O. and Deane, C. and Dunne, P. and Hussey, A. and Gorman, M. and Moroney, J.T., Patient and hospital delays in acute ischaemic stroke in a Dublin teaching hospital, Irish Medical Journal, 96, (6), 2003, p167-171 Journal Article, 2003

Pittock S.J, Meldrum D, Hardiman O, Thornton J, Brennan P, Moroney J.T, The Oxfordshire Community Stroke Project Classification: Correlation with imaging, associated complications, and prediction of outcome in acute ischemic stroke, Journal of Stroke and Cerebrovascular Diseases, 12, (1), 2003, p1 - 7 Journal Article, 2003 URL DOI

Meldrum D, Cahalane E, Keogan F, Hardiman O, Maximum voluntary isometric contraction: Investigation of reliability and learning effect, Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders, 4, (1), 2003, p36 - 44 Journal Article, 2003 DOI URL

Pittock S.J, Meldrum D, Dhuill C.N, Hardiman O, Moroney J.T, The Orpington Prognostic Scale Within the First 48 Hours of Admission as a Predictor of Outcome in Ischemic Stroke, Journal of Stroke and Cerebrovascular Diseases, 12, (4), 2003, p175 - 181 Journal Article, 2003 URL DOI

Pittock S.J, Meldrum D, Hardiman O, The "spray can" sign: Validation of a clinical observation in chronic inflammatory demyelinating polyneuropathy, Archives of Neurology, 59, (10), 2002, p1637 - 1640 Journal Article, 2002 URL DOI

Pittock, S.J. and Meldrum, D. and Hardiman, O., The {", Archives of Neurology, 59, (10), 2002, p1637-1640 Journal Article, 2002

Meldrum, D. and Finn, A.M., An Investigation of Balance Function in Elderly Subjects Who Have and Have Not Fallen, Physiotherapy (United Kingdom), 79, (12), 1993, p839-842 Journal Article, 1993

Research Expertise

Description

Dr. Meldrum's research is focused on the area of neurological rehabilitation, in particular measurement systems of physical impairment, technology in rehabilitation (for example strain gauge systems for the measurement of muscle strength), computerised three dimensional movement analysis (for the measurement of human gait) and computerised dynamic posturography (for the measurement of balance). Dr. Meldrum has researched extensively in Neuromuscular diseases (such as prior polio and Motor Neuron Disease) and in Vestibular rehabilitation (rehabilitation of those with dizziness, vertigo and imbalance).

Projects

  • Title
    • Verti-Genius: A mobile health and wearable-sensor based exercise application for the rehabilitation of dizziness, vertigo and balance problems
  • Summary
    • 35% of adults have balance impairment; dizziness and vertigo are prevalent in 20% and a combination of both results in a 12 fold risk of falling which is associated with high morbidity and significant mortality. Across jurisdictions of UK/Ireland, US and Australia first episode of vertigo equates to 1.8 million per year, 80% of whom will consult a medical professional and 80% of whom will have a recurrence. Dizziness and imbalance can be rehabilitated effectively with physical exercise, a specialist form of treatment known as vestibular rehabilitation, but at present access to this treatment and expert capacity is low leading to an impaired population that is under-served. Mobile and personalised health are poised to become major disruptive technologies that will change fundamentally the way health is delivered.Mobile health will solve the problems of access to care and patient education, allowing remote consultation and monitoring. Ultimately, analytics from digitally collected data will provide evidence and better outcomes for patients. It is acknowledged that health experts will develop the most successful applications. Exercise prescription has traditionally been time consuming and provides no feedback to either patient or therapist on performance, adherence and response. Pen and paper methods are the mainstay mode of delivery, but this is set to change. Our proposal aims to commercialise an unmet need in the rehabilitation space by digitally delivering a specialised, scientifically validated method of rehabilitation to patients who have dizziness, vertigo and balance problems. We have developed and tested a prototype digital health platform entitled "Verti-Genius" that is capable of providing a rehabilitation and education programme for individuals with dizziness and balance disorders via an e-tablet or Smartphone. Currently prescribed exercise programmes have been mapped to software that is interactive and measures exercise parameters that are critical to treatment success. A head mounted sensor has been incorporated that enables tracking of head movement (a crucial component of the exercises). Verti-Genius connects the home rehabilitation programme to the clinic, educates and empowers the patient, thus reducing therapist time and costs. In two clinical studies of Verti-Genius, patient and therapist usability and acceptance were high.
  • Funding Agency
    • Enterprise Ireland
  • Date From
    • Jan 2019
  • Date To
    • Dec 2019
  • Title
    • Tricals Reveals
  • Summary
    • ALS is a progressive Neurodegenerative condition with a prognosis of between two and five years. Respiratory insufficiency is the primary cause of morbidity and mortality in ALS. Respiratory muscle weakness impedes the mechanics of the respiratory system; lung volumes are reduced and ventilation perfusion mismatching occurs. The purpose of this study is to compare real world experience to current measurements of ventilatory function by evaluating (1) the impact of declining respiratory function on secretion management and (2) the frequency and impact of respiratory tract infection.
  • Funding Agency
    • Research Motor Neuron
  • Date From
    • Jan 2018
  • Date To
    • Dec 2020

Recognition

Memberships

Irish Society of Chartered Physiotherapists 1990 – 2019