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Dr. Micheál Mac Aogáin
Clinical Tutor, Clinical Microbiology

Publications and Further Research Outputs

Peer-Reviewed Publications

Mac Aogáin M, Fennelly N, Walsh A, Lynagh Y, Bekaert M, Lawlor B, Walsh P , Kelly B, Rogers TR, Crowley B , Fourteen Draft Genome Sequences for the First Reported Cases of Azithromycin-Resistant Neisseria gonorrhoeae in Ireland., Genome Announcements, 5, (23), 2017 Journal Article, 2017

Lynch M, Walsh TA, Marszalowska I, Webb AE, MacAogain M, Rogers TR, Windle H, Kelleher D, O'Connell MJ, Loscher CE., Surface layer proteins from virulent Clostridium difficile ribotypes exhibit signatures of positive selection with consequences for innate immune response., BMC Evolutionary Biology, 17, (1), 2017, p90- Journal Article, 2017 DOI

Gautam, S.S. and Aogáin, M.M. and O'Toole, R.F., Draft genome sequence of the first confirmed isolate of multidrug-resistant Mycobacterium tuberculosis in Tasmania, Genome Announcements, 5, (44), 2017, pe01230-17 Journal Article, 2017 DOI TARA - Full Text

Lynch M, Walsh TA, Marszalowska I, Webb AE, MacAogain M, Rogers TR, Windle H, Kelleher D, O'Connell MJ, Loscher CE., Surface layer proteins from virulent Clostridium difficile ribotypes exhibit signatures of positive selection with consequences for innate immune response., BMC Evolutionary Biology, 17, (1), 2017, p90 - 90 Journal Article, 2017 URL

Moloney G, Mac Aogáin M, Kelleghan M, O'Connell B, Hurley C, Montague E, Conlon M, Murray H, Rogers TR, Possible Interplay Between Hospital and Community Transmission of a Novel Clostridium Difficile Sequence Type 295 Recognized by Next-Generation Sequencing., Infection control and hospital epidemiology, 37, (6), 2016, p680-4 Journal Article, 2016 DOI

Miche􏰀al Mac Aog􏰀ain, Helen Miajlovic, Geraldine Moloney, Sanjay H. Chotirmall, Thomas R. Rogers and Stephen G. J. Smith, Identification of a novel sequence type of Escherichia coli as the causative agent of pyelonephritis and bloodstream infection, JMM Case Reports, 3, 2016, p1 - 4 Journal Article, 2016 DOI URL TARA - Full Text

Mac Aogáin M, Miajlovic H, Moloney G, Chotirmall SH, Rogers TR, Smith SG., Identification of a novel sequence type of Escherichia coli as the causative agent of pyelonephritis and bloodstream infection., JMM Case Reports, 3, (5), 2016 Journal Article, 2016 URL

McElroy MC, Hill M, Moloney G, Mac Aogáin M, McGettrick S, O'Doherty Á, Rogers TR., Typhlocolitis associated with Clostridium difficile ribotypes 078 and 110 in neonatal piglets from a commercial Irish pig herd., Irish Veterinary Journal, 69, (10), 2016 Journal Article, 2016 URL URL

Micheál Mac Aogáin. Shauna Kilkenny, Claire Walsh, Sinéad Lindsay, Geraldine Moloney, Trefor Morris, Sophie Jones, Thomas R. Rogers, Identification of a novel mutation at the primary dimer interface of GyrA conferring fluoroquinolone resistance in Clostridium difficile, Journal of Global Antimicrobial Resistance, 2015 Journal Article, 2015 URL URL TARA - Full Text

Brown AF, Murphy AG, Lalor SJ, Leech JM, O'Keeffe KM, Mac Aogáin M, O'Halloran DP, Lacey KA, Tavakol M, Hearnden CH, Fitzgerald-Hughes D, Humphreys H, Fennell JP, van Wamel WJ, Foster TJ, Geoghegan JA, Lavelle EC, Rogers TR, McLoughlin RM, Memory Th1 Cells Are Protective in Invasive Staphylococcus aureus Infection., PLoS pathogens, 11, (11), 2015, pe1005226 Journal Article, 2015 TARA - Full Text DOI

Micheál Mac Aogáin, Geraldine Moloney, Shauna Kilkenny, Mary Kelleher, May Kelleghan, Brieda Boyle, Thomas Rogers, Whole-genome sequencing improves discrimination of relapse from reinfection and identifies transmission events among patients with recurrent Clostridium difficile infections, Journal of Hospital Infection, 2015 Journal Article, 2015

Yvonne Lynagh, Micheál Mac Aogáin, Thomas Rogers, Magnus Unemo, Brendan Crowley, Detailed characterisation of the first high-level azithromycin-resistant Neisseria gonorrhoeae cases in Ireland, The Journal of Antimicrobial Chemotherapy, 2015 Journal Article, 2015

Kinnevey PM, Shore AC, Mac Aogáin M, Creamer E, Brennan GI, Humphreys H, Rogers TR, O'Connell B, Coleman DC, Enhanced tracking of the nosocomial transmission of endemic ST22-MRSA-IV among patients and environmental sites using whole-genome sequencing., Journal of clinical microbiology, 2015 Journal Article, 2015

Miajlovic H, Mac Aogáin M, Collins CJ, Rogers TR, Smith SG, Characterization of Escherichia coli bloodstream isolates associated with mortality., Journal of medical microbiology, 2015 Journal Article, 2015

Roycroft E, Mac Aogáin M, O'Toole RF, Fitzgibbon M, Rogers TR, Draft Genome Sequence of the First Isolate of Extensively Drug-Resistant Mycobacterium tuberculosis in Ireland., Genome announcements, 2, (5), 2014 Journal Article, 2014 TARA - Full Text DOI

Mac Aogáin M, Bower JE, Basu I, Freeman JT, O'Toole RF, Draft Genome Sequence of a Drug-Susceptible New Zealand Isolate of Mycobacterium tuberculosis Lineage 3., Genome announcements, 3, (3), 2014 Journal Article, 2014 DOI TARA - Full Text

Roycroft E, Mac Aogáin M, O'Toole RF, Fitzgibbon M, Rogers TR., Draft Genome Sequence of the First Isolate of Extensively Drug-Resistant Mycobacterium tuberculosis in Ireland., Genome announcements, 2014, ppii: e01002-14 Journal Article, 2014

Mac Aogáin M, Johari BM, Bower JE, O'Toole RF, Draft Genome Sequence of a Multidrug-Resistant New Zealand Isolate of Mycobacterium tuberculosis Lineage 3., Genome announcements, 2, (5), 2014 Journal Article, 2014 DOI TARA - Full Text URL

O'Toole RF, Johari BM, Mac Aogáin M, Rogers TR, Bower JE, Basu I, Freeman JT., Short communication, Genome Announcements, 2 , (3), 2014, pe00319-14 Journal Article, 2014 URL DOI

Mac Aogáin M, Mooij MJ, McCarthy RR, Plower E, Wang YP, Tian ZX, Dobson A, Morrissey J, Adams C, O'Gara F, The non-classical ArsR-family repressor PyeR (PA4354) modulates biofilm formation in Pseudomonas aeruginosa., Microbiology (Reading, England), 158, (Pt 10), 2012, p2598-609 Journal Article, 2012

Fargier E, Mac Aogáin M, Mooij MJ, Woods DF, Morrissey JP, Dobson AD, Adams C, O'Gara F, MexT functions as a redox-responsive regulator modulating disulfide stress resistance in Pseudomonas aeruginosa., Journal of bacteriology, 194, (13), 2012, p3502-11 Journal Article, 2012

Mac Aogáin M, Kulah C, Rijnsburger M, Celebi G, Savelkoul PH, O'Gara F, Mooij MJ, Characterization of imipenem resistance mechanisms in Pseudomonas aeruginosa isolates from Turkey., Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 18, (7), 2012, pE262-5 Journal Article, 2012

Mac Aogáin M, Mooij MJ, Adams C, Clair J, O'Gara F, Emergence of extended-spectrum beta-lactamase and fluoroquinolone resistance genes among Irish multidrug-resistant isolates., Diagnostic microbiology and infectious disease, 67, (1), 2010, p106-9 Journal Article, 2010

Tian ZX, Fargier E, Mac Aogáin M, Adams C, Wang YP, O'Gara F, Transcriptome profiling defines a novel regulon modulated by the LysR-type transcriptional regulator MexT in Pseudomonas aeruginosa., Nucleic acids research, 37, (22), 2009, p7546-59 Journal Article, 2009

Tian ZX, Mac Aogáin M, O'Connor HF, Fargier E, Mooij MJ, Adams C, Wang YP, O'Gara F, MexT modulates virulence determinants in Pseudomonas aeruginosa independent of the MexEF-OprN efflux pump., Microbial pathogenesis, 47, (4), 2009, p237-41 Journal Article, 2009

Research Expertise

Projects

  • Title
    • Evaluation of Next Generation Sequencing to Investigate the Epidemiology of Clostridium difficile Infection
  • Funding Agency
    • Health Reseach Board
  • Date From
    • 2014
  • Date To
    • 2017
  • Title
    • New insights into the transmission dynamics of healthcareassociated Clostridium difficile infection through whole-genome sequencing
  • Funding Agency
    • Astellas Pharma Ireland
  • Date From
    • 2013
  • Date To
    • 2014
  • Title
    • Molecular epidemiology and transcriptome sequencing of Irish Clostridium difficile isolates.
  • Funding Agency
    • Healthcare infection society
  • Date From
    • 2013
  • Date To
    • 2015