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Dr. Elaine Kenny
Senior Research Fellow, Psychiatry

Publications and Further Research Outputs

Peer-Reviewed Publications

Andreev D., O'Connor P., Fahey C., Kenny E., Terenin I., Dmitriev S., Cormican P., Morris D., Shatsky I., Baranov P., Translation of 5' leaders is pervasive in genes resistant to eIF2 repression, eLife, 4, 2015, pe03971 Journal Article, 2015 DOI

Aloraifi F, McDevitt T, Martiniano R, McGreevy J, McLaughlin R, Egan CM, Cody N, Meany M, Kenny E, Green AJ, Bradley DG, Geraghty JG, Bracken AP., Detection of novel germline mutations for breast cancer in non-BRCA1/2 families., FEBS J., 282, (17), 2015, p3424 - 3437 Journal Article, 2015 DOI

Hong Lee, S., Byrne, E.M., Hultman, C.M., Kähler, A., Vinkhuyzen, A.A., Ripke, S., Andreassen, O.A., Frisell, T., Gusev, A., Hu, X., Karlsson, R., Mantzioris, V.X., McGrath, J.J., Mehta, D., Stahl, E.A., Zhao, Q., Kendler, K.S., Sullivan, P.F., Price, A.L., O'Donovan, M., Okada, Y., Mowry, B.J., Raychaudhuri, S., Wray, N.R., Agartz, I., Amin, F., Azevedo, M.H., Bass, N., Black, D.W., Blackwood, D.H.R., Bruggeman, R., Buccola, N.G., Choudhury, K., Cloninger, C.R., Corvin, A., Craddock, N., Daly, M.J., Datta, S., Donohoe, G.J., Duan, J., Dudbridge, F., Fanous, A., Freedman, R., Freimer, N.B., Friedl, M., Gill, M., Gurling, H., Haan, L.D., Hamshere, M.L., Hartmann, A.M., Holmans, P.A., Kahn, R.S., Keller, M.C., Kenny, E., Kirov, G.K., Krabbendam, L., Krasucki, R., Lawrence, J., Lencz, T., Levinson, D.F., Lieberman, J.A., Lin, D.-Y., Linszen, D.H., Magnusson, P.K.E., Maier, W., Malhotra, A.K., Mattheisen, M., Mattingsdal, M., McCarroll, S.A., Medeiros, H., Melle, I., Milanova, V., Myin-Germeys, I., Neale, B.M., Ophoff, R.A., Owen, M.J., Pimm, J., Purcell, S.M., Puri, V., Quested, D.J., Rossin, L., Ruderfer, D., Sanders, A.R., Shi, J., Sklar, P., St Clair, D., Scott Stroup, T., Van Os, J., Visscher, P.M., Wiersma, D., Zammit, S., Byerley, W., Cahn, W., Cantor, R.M., Cichon, S., Cormican, P., Curtis, D., Djurovic, S., Escott-Price, V., Gejman, P.V., Georgieva, L., Giegling, I., Hansen, T.F., Ingason, Andrés, Kim, Y., Konte, B., Lee, P.H., McIntosh, A., McQuillin, A., Morris, D.W., Nöthen, M.M., O'Dushlaine, C., Olincy, A., Olsen, L., Pato, C.N., Pato, M.T., Pickard, B.S., Posthuma, D., Rasmussen, H.B., Rietschel, M., Rujescu, D., Schulze, T.G., Silverman, J.M., Thirumalai, S., Werge, T., Louis Bridges, S., Choi, H.K., Coenen, M.J.H., De Vries, N., Dieud, P., Greenberg, J.D., Huizinga, T.W.J., Padyukov, L., Siminovitch, K.A., Tak, P.P., Worthington, J., De Jager, P.L., Denny, J.C., Gregersen, P.K., Klareskog, L., Mariette, X., Plenge, R.M., Van Laar, M., Van Riel, P., New data and an old puzzle: The negative association between schizophrenia and rheumatoid arthritis, International Journal of Epidemiology, 44, (5), 2015, p1706-1721 Journal Article, 2015 TARA - Full Text DOI

Rolfe RA, Nowlan NC, Kenny EM, Cormican P, Morris DW, Prendergast PJ, Kelly D, Murphy P., Identification of mechanosensitive genes during skeletal development: alteration of genes associated with cytoskeletal rearrangement and cell signalling pathways., BioMedCentral Genomics, 15, 2014, p1 - 23 Journal Article, 2014 TARA - Full Text

Douglas A., Vance D., Kenny E., Morris D., Maxwell A., Maxwell A., McKnight A., Next-generation sequencing of the mitochondrial genome and association with IgA nephropathy in a renal transplant population, Scientific Reports, 4, 2014 Journal Article, 2014 DOI

Kenny EM, Cormican P, Furlong S, Heron E, Kenny G, Fahey C, Kelleher E, Ennis S, Tropea D, Anney R, Corvin AP, Donohoe G, Gallagher L, Gill M, Morris DW, Excess of rare novel loss-of-function variants in synaptic genes in schizophrenia and autism spectrum disorders., Molecular psychiatry, 19, 2014, p872-879 Journal Article, 2014 DOI TARA - Full Text

Morris DW, Pearson RD, Cormican P, Kenny EM, O'Dushlaine CT, Perreault LP, Giannoulatou E, Tropea D, Maher BS, Wormley B, Kelleher E, Fahey C, Molinos I, Bellini S, Pirinen M, Strange A, Freeman C, Thiselton DL, Elves RL, Regan R, Ennis S, Dinan TG, McDonald C, Murphy KC, O'Callaghan E, Waddington JL, Walsh D, O'Donovan M, Grozeva D, Craddock N, Stone J, Scolnick E, Purcell S, Sklar P, Coe B, Eichler EE, Ophoff R, Buizer J, Szatkiewicz J, Hultman C, Sullivan P, Gurling H, McQuillin A, St Clair D, Rees E, Kirov G, Walters J, Blackwood D, Johnstone M, Donohoe G, O'Neill FA, Kendler KS, Gill M, Riley BP, Spencer CC, Corvin A, An inherited duplication at the gene p21 Protein-Activated Kinase 7 (PAK7) is a risk factor for psychosis., Human molecular genetics, 23, (12), 2014, p3316-26 Journal Article, 2014 TARA - Full Text DOI

Rolfe RA, Kenny EM, Cormican P, Murphy P, Transcriptome analysis of the mouse E14.5 (TS23) developing humerus and differential expression in muscle-less mutant embryos lacking mechanical stimulation., Genomics data, 2, 2014, p32-6 Journal Article, 2014 DOI

Quinn EM, Cormican P, Kenny EM, Hill M, Anney R, Gill M, Corvin A, Morris DW. , Development of strategies for SNP detection in RNA-seq data: application to lymphoblastoid cell lines and evaluation using 1000 genomes data., PLos One, 2013 Journal Article, 2013

Lee, S.H., Ripke, S., Neale, B.M., (...), Kendler, K.S., Wray, N.R., Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs, Nature Genetics , 45, (9), 2013, p984-994 Journal Article, 2013 URL TARA - Full Text

Kenna KP, McLaughlin RL, Byrne S, Elamin M, Heverin M, Kenny EM, Cormican P, Morris DW, Donaghy CG, Bradley DG, Hardiman O, Delineating the genetic heterogeneity of ALS using targeted high-throughput sequencing., Journal of medical genetics, 50, (11), 2013, p776-83 Journal Article, 2013 TARA - Full Text DOI

Foley C, Chapwanya A, Creevey CJ, Narciandi F, Morris D, Kenny EM, Cormican P, Callanan JJ, O'Farrelly C, Meade KG, Global endometrial transcriptomic profiling: transient immune activation precedes tissue proliferation and repair in healthy beef cows., BMC genomics, 13, (1), 2012, p489 Journal Article, 2012 DOI TARA - Full Text

Connell S, Meade KG, Allan B, Lloyd AT, Kenny E, Cormican P, Morris DW, Bradley DG, O'Farrelly C, Avian resistance to Campylobacter jejuni colonization is associated with an intestinal immunogene expression signature identified by mRNA sequencing., PloS one, 7, (8), 2012, pe40409 Journal Article, 2012 TARA - Full Text DOI

Lips ES, Cornelisse LN, Toonen RF, Min JL, Hultman CM, Holmans PA, O'Donovan MC, Purcell SM, Smit AB, Verhage M, Sullivan PF, Visscher PM, Posthuma D, Functional gene group analysis identifies synaptic gene groups as risk factor for schizophrenia., Molecular Psychiatry, 17, (10), 2012, p996-1006 Journal Article, 2012 DOI TARA - Full Text

Kenny EM, Cormican P, Gilks WP, Gates AS, O'Dushlaine CT, Pinto C, Corvin AP, Gill M, Morris DW, Multiplex Target Enrichment Using DNA Indexing for Ultra-High Throughput SNP Detection., DNA research : an international journal for rapid publication of reports on genes and genomes, 18, (1), 2011, p31-38 Journal Article, 2011 DOI TARA - Full Text

Anney RJ, Kenny EM, O'Dushlaine C, Yaspan BL, Parkhomenka E, Buxbaum JD, Sutcliffe J, Gill M, Gallagher L; Autism Genome Project, Gene-ontology enrichment analysis in two independent family-based samples highlights biologically plausible processes for autism spectrum disorders., Eur J Human Genetics, 19, (10), 2011, p1082 - 1089 Journal Article, 2011 DOI TARA - Full Text

O'Dushlaine C, Kenny E, Heron E, Donohoe G, Gill M, Morris D, Consortium IS, Corvin A, Molecular pathways involved in neuronal cell adhesion and membrane scaffolding contribute to schizophrenia and bipolar disorder susceptibility., Molecular Psychiatry, 16, (3), 2011, p286-292 Journal Article, 2011 DOI TARA - Full Text

Fitzpatrick DA, O'Brien J, Moran C, Hasin N, Kenny E, Cormican P, Gates A, Morris DW, Jones GW, Assessment of Inactivating Stop Codon Mutations in Forty Saccharomyces cerevisiae Strains: Implications for [PSI] Prion- Mediated Phenotypes., PLoS One, 6, (12, e28684), 2011 Journal Article, 2011 TARA - Full Text DOI

Hill MJ, Kenny E, Roche S, Morris DW, Corvin A, Hawi Z, Gill M, Anney RJ, Allelic expression imbalance of the schizophrenia susceptibility gene CHI3L1: evidence of cis-acting variation and tissue specific regulation., Psychiatric genetics, 21, (6), 2011, p281-286 Journal Article, 2011 DOI

Casey J, Kawaguchi R, Morrissey M, Sun H, McGettigan P, Nielsen JE, Conroy J, Regan R, Kenny E, Cormican P, Morris DW, Tormey P, Chróinín MN, Kennedy BN, Lynch S, Green A, Ennis S, First implication of STRA6 mutations in isolated anophthalmia, microphthalmia, and coloboma: a new dimension to the STRA6 phenotype., Human mutation, 32, (12), 2011, p1417-26 Journal Article, 2011 URL

Raychaudhuri S, Korn JM, McCarroll SA, International Schizophrenia Consortium, Altshuler D, Sklar P, Purcell S, Daly MJ, Accurately assessing the risk of schizophrenia conferred by rare copy-number variation affecting genes with brain function., PLoS genetics, 6, (9, e1001097), 2010 Journal Article, 2010 DOI TARA - Full Text

O'Dushlaine C, Kenny E, Heron EA, Segurado R, Gill M, Morris DW, Corvin A, The SNP ratio test: pathway analysis of genome-wide association datasets., Bioinformatics, 2009 Journal Article, 2009

International Schizophrenia Consortium, Common polygenic variation contributes to risk of schizophrenia and bipolar disorder., Nature, 460, (7256), 2009, p748-752 Journal Article, 2009 DOI

Lorraine O'Driscoll*, Elaine Kenny*, Jai P Mehta, Padraig Doolan, Helena Joyce, Patrick Gammell, Arnold Hill, Brendan O'Daly, Donal O'Gorman and Martin Clynes, Feasibility and Relevance of Global Expression Profiling of Gene Transcripts in Serum from Breast Cancer Patients Using Whole Genome Microarrays and Quantitative RT-PCR, Cancer Genomics and Proteomics, 5, 2008 Journal Article, 2008

Yang MS, Morris DW, Kenny E, O'Dushalaine CT, Schwaiger S, Nangle, JM, Clarke S, Scully P, Quinn J, Meagher D, Baldwin P, Crumlish N, O'Callaghan E, Waddington JL, Gill M, Corvin A, Chitinase-3-Like1 (CHI3L1) Gene and Schizophrenia: Genetic Association and a Potential functional Mechanism. , Biological Psychaitry, 64, (2), 2008, p98 - 103 Journal Article, 2008 URL DOI URL

International Schizophrenia Consortium, Rare chromosomal deletions and duplications increase risk of schizophrenia., Nature, 455, (7210), 2008, p237 - 241 Journal Article, 2008 TARA - Full Text DOI

Anney, RJ, Kenny, E, O'Dushlaine, CT, Lasky-Su, J, Franke, B, Morris, DW, Neale, BM, Asherson, P, Faraone, SV, Gill, M, Non-random error in genotype calling procedures: Implications for family-based and case-control genome-wide association studies., American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 147B, (8), 2008 Journal Article, 2008 DOI

Anney, RJ, Lasky-Su, J, O'Dúshláine, C, Kenny, E, Neale, BM, Mulligan, A, Franke, B, Zhou, K, Chen, W, Christiansen, H, Arias-Vásquez, A, Banaschewski, T, Buitelaar, J, Ebstein, R, Miranda, A, Mulas, F, Oades, RD, Roeyers, H, Rothenberger, A, Sergeant, J, Sonuga-Barke, E, Steinhausen, H, Asherson, P, Faraone, SV, Gill, M, Conduct disorder and ADHD: Evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study., American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 147B, (8), 2008 Journal Article, 2008 DOI

Martinez V, Kennedy S, Doolan P, Gammell P, Joyce H, Kenny E, Prakash Mehta J, Ryan E, O'Connor R, Crown J, Clynes M, O'Driscoll L., Drug metabolism-related genes as potential biomarkers: analysis of expression in normal and tumour breast tissue., Breast Cancer Research and Treatment, 2007 Journal Article, 2007 URL

Roy S, Kenny E, Kennedy S, Larkin A, Ballot J, Perez De Villarreal M, Crown J, O'Driscoll L., MDR1/P-glycoprotein and MRP-1 mRNA and protein expression in non-small cell lung cancer, Anticancer Research, 27, (3A), 2007, p1325 - 1330 Journal Article, 2007 URL

O'Driscoll L,* Kenny E,* Perez de Villarreal M, Clynes M., Detection of Specific mRNAs in Culture Medium Conditioned by Human Tumour Cells: Potential for New Class of Cancer Biomarkers in Serum , Cancer Genomics and Proteomics, 2, 2005, p43 - 52 Journal Article, 2005

Research Expertise


Bioinformatics; Genomic structure and function, molecular approaches to gene function; Human genetics; Molecular population genetics; Population structure and dynamics; Psychiatric genetics; Quantitative and molecular genetics; Quantitative genetics and genetics of complex traits; Regulatory methods of gene expression; Schizophrenia