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Dr. Ignacio Martin-Loeches
Clinical Senior Lecturer, Clinical Medicine

Biography

My name is Ignacio Martin-Loeches (PhD, EMBA, FJFICMI) and I'm Vice-Chair of Intensive Care Medicine at St James's University Hospital, Dublin , Senior Clinical Lecturer and Research Director of the Multidisciplinary Intensive Care Research Organization (MICRO) at Trinity College, Dublin. I'm holding an executive MBA in healthcare administration by IESE Business School since 2012.

From 2008 to 2009 I was a Senior Consultant and Lead Clinician in Intensive Care Medicine at the University Hospital Tarragona Joan XXIII in Taragona. In 2011 I was appointed Director of Research at the Corporacion Sanitaria Parc Tauli, Centre for Critical Illness and Data Sciences Research, which is affiliated with the Universidad de Barcelona. I was also appointed Associate Professor at the University Autonoma of Barcelona,

In July 2014 moved to Dublin, taking a post as Consultant Intensivist at St James's Hospital. Shortly thereafter I was appointed Senior Lecturer at Trinity College Dublin.

I'm currently the chair of COBATRICE at ESICM and recently appointed as in the Steering committee member of the Surviving Sepsis Campaign (SSC).

My publications include over 250 manuscripts published in international peer-reviewed journals and 222 in Pubmed until today. These publications have been cited 6,224 times and with a current H index of 40with current research grants up to €1Million with European Regional Development Funds (ERDF) grants as Principal Investigator.

Publications and Further Research Outputs

Peer-Reviewed Publications

Meyfroidt G, Gunst J, Martin-Loeches I, Smith M, Robba C, Taccone FS, Citerio G, Management of the brain-dead donor in the ICU: general and specific therapy to improve transplantable organ quality., Intensive care medicine, 2019 Journal Article, 2019

Weiss E, Zahar JR, Alder J, Asehnoune K, Bassetti M, Bonten MJM, Chastre J, De Waele J, Dimopoulos G, Eggimann P, Engelhardt M, Ewig S, Kollef M, Timsit JF, Elaboration of consensus clinical endpoints to evaluate antimicrobial treatment efficacy in future HABP/VABP clinical trials., Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2019 Journal Article, 2019

Rouzé A, Martin-Loeches I, Nseir S, Improved Endotracheal Tubes for Prevention of Ventilator-Associated Pneumonia: Better Than Silver and Gold?, Respiratory care, 2019 Journal Article, 2019

Martin-Loeches I, Guia MC, Vallecoccia MS, Suarez D, Ibarz M, Irazabal M, Ferrer R, Artigas A, Risk factors for mortality in elderly and very elderly critically ill patients with sepsis: a prospective, observational, multicenter cohort study., Annals of intensive care, 2019 Journal Article, 2019

Torres A, Chalmers JD, Dela Cruz CS, Dominedò C, Kollef M, Martin-Loeches I, Niederman M, Wunderink RG, Challenges in severe community-acquired pneumonia: a point-of-view review., Intensive care medicine, 2019 Journal Article, 2019

Martin-Loeches I, Torres A, ENIRRIs Clinical Research Collaboration, The European Network for ICU-Related Respiratory Infections (ENIRRIs) ERS Clinical Research Collaboration., The European respiratory journal, 2019 Journal Article, 2019

Kelly DN, Martin-Loeches I, Comparing current US and European guidelines for nosocomial pneumonia., Current opinion in pulmonary medicine, 2018 Journal Article, 2018

Martin-Loeches I, Depuydt P, Niederman MS, Beat around the bush for VA-LRTI., Intensive care medicine, 2018 Journal Article, 2018

Rouzé A, Martin-Loeches I, Nseir S, Airway Devices in Ventilator-Associated Pneumonia Pathogenesis and Prevention., Clinics in chest medicine, 2018 Journal Article, 2018

Nseir S, Martin-Loeches I, Hot topics in ventilator-associated pneumonia., Annals of translational medicine, 2018 Journal Article, 2018

Li Bassi G, Prats RG, Artigas A, Xiol EA, Marti JD, Ranzani OT, Rigol M, Fernandez L, Meli A, Battaglini D, Luque N, Ferrer M, Martin-Loeches I, Torres A, Appraisal of systemic inflammation and diagnostic markers in a porcine model of VAP: secondary analysis from a study on novel preventive strategies., Intensive care medicine experimental, 2018 Journal Article, 2018

De Pascale G, Bello G, Dell'Anna AM, Montini L, Antonelli M, Moreno G, Rodriguez A, Martin-Loeches I, Steroids and severe pneumonia. Ready for the winter? Discussion on "Corticosteroid treatment in critically ill patients with severe influenza pneumonia: a propensity score matching study"., Intensive care medicine, 2018 Journal Article, 2018

Mathieu C, Pastene B, Cassir N, Martin-Loeches I, Leone M, Efficacy and safety of antimicrobial de-escalation as a clinical strategy., Expert review of anti-infective therapy, 2018 Journal Article, 2018

Keane S, Geoghegan P, Povoa P, Nseir S, Rodriguez A, Martin-Loeches I, Systematic review on the first line treatment of amphotericin B in critically ill adults with candidemia or invasive candidiasis., Expert review of anti-infective therapy, 2018 Journal Article, 2018

Bos LDJ, Azoulay E, Martin-Loeches I, Future of the ICU: finding treatable needles in the data haystack., Intensive care medicine, 2018 Journal Article, 2018

Sakr Y, Jaschinski U, Wittebole X, Szakmany T, Lipman J, Ñamendys-Silva SA, Martin-Loeches I, Leone M, Lupu MN, Vincent JL, ICON Investigators, Sepsis in Intensive Care Unit Patients: Worldwide Data From the Intensive Care over Nations Audit., Open forum infectious diseases, 2018 Journal Article, 2018

Coelho L, Rabello L, Salluh J, Martin-Loeches I, Rodriguez A, Nseir S, Gomes JA, Povoa P, TAVeM study Group, C-reactive protein and procalcitonin profile in ventilator-associated lower respiratory infections., Journal of critical care, 2018 Journal Article, 2018

Martin C, Cortegiani A, Gregoretti C, Martin-Loeches I, Ichai C, Leone M, Marx G, Einav S, Choice of fluids in critically ill patients., BMC anesthesiology, 2018 Journal Article, 2018

Manzano D, Izquierdo-Garcia JL, Martín-Loeches I, Lorente JA, Influenza A: New Therapeutic Targets for a Deadly Disease., Archivos de bronconeumologia, 2018 Journal Article, 2018

Bassetti M, Scudeller L, Giacobbe DR, Lamoth F, Righi E, Zuccaro V, Grecchi C, Rebuffi C, Akova M, Alastruey-Izquierdo A, Arikan-Akdagli S, Mycoses Study Group Education and Research Consortium (MSGERC), Developing definitions for invasive fungal diseases in critically ill adult patients in intensive care units. Protocol of the FUNgal infections Definitions in ICU patients (FUNDICU) project., Mycoses, 2018 Journal Article, 2018

Almansa R, Nogales L, Martín-Fernández M, Batlle M, Villareal E, Rico L, Ortega A, López-Campos G, Andaluz-Ojeda D, Ramírez P, Socias L, Tamayo L, Martín-Loeches I, Transcriptomic depression of immunological synapse as a signature of ventilator-associated pneumonia., Annals of translational medicine, 2018 Journal Article, 2018

Radovanovic D, Sotgiu G, Jankovic M, Mahesh PA, Marcos PJ, Abdalla MI, Di Pasquale MF, Gramegna A, Terraneo S, Blasi F, Santus P, Aliberti S, GLIMP Study Group, An international perspective on hospitalized patients with viral community-acquired pneumonia., European journal of internal medicine, 2018 Journal Article, 2018

Keane S, Vallecoccia MS, Nseir S, Martin-Loeches I, How Can We Distinguish Ventilator-Associated Tracheobronchitis from Pneumonia?, Clinics in chest medicine, 2018 Journal Article, 2018

Ceccato A, Cilloniz C, Martin-Loeches I, Ranzani OT, Gabarrus A, Bueno L, Garcia-Vidal C, Ferrer M, Niederman MS, Torres A, Effect of Combined ß-Lactam/Macrolide Therapy on Mortality According to the Microbial Etiology and Inflammatory Status of Patients With Community-Acquired Pneumonia., Chest, 2018 Journal Article, 2018

, Sepsis: frontiers in supportive care, organisation and research, Intensive care medicine, 2017 Journal Article, 2017

, Tools for outcome prediction in patients with community acquired pneumonia, Expert Review of Clinical Pharmacology, 2017 Journal Article, 2017

, Invasive Candida Infections in Liver Transplant Recipients: Clinical Features and Risk Factors for Mortality., Transplantation Direct, 2017 Journal Article, 2017

, Collaborative approach of individual participant data of prospective studies of de-escalation in non-immunosuppressed critically ill patients with sepsis, Expert Review of Clinical Pharmacology, 2017 Journal Article, 2017

, Impact of Source Control in Patients With Severe Sepsis and Septic Shock, Critical Care Medicine, 2017 Journal Article, 2017

, Clinical characteristics and predictors of mortality in cirrhotic patients with candidemia and intra-abdominal candidiasis: a multicenter study, Intensive care medicine, 2017 Journal Article, 2017

Martin-Loeches Ignacio, Muriel-Bombin Arturo, Ferrer Ricard, Artigas Antonio, Sole-Violan Jordi, Lorente Leonardo, Andaluz-Ojeda David, Prina-Mello Adriele, Herran-Monge Ruben, Suberviola Borja, The protective association of endogenous immunoglobulins against sepsis mortality is restricted to patients with moderate organ failure , Annals of Intensive Care , 7 , (1 ), 2017, p44 - Journal Article, 2017 TARA - Full Text

, The pharmacological management of severe influenza infection--`existing and emerging therapies", Expert Review of Clinical Pharmacology, 2017 Journal Article, 2017

, What were you able to do in your daily life? Performance status for the critically ill patient, 2017 Journal Article, 2017

, The research agenda in VAP/HAP: next steps, Intensive Care Medicine, 2017 Journal Article, 2017

, Focus on infection and sepsis 2017, Intensive Care Medicine, 2017 Journal Article, 2017

, Epidemiology of sepsis in Catalonia: analysis of incidence and outcomes in a European setting, Annals of Intensive Care, 2017 Journal Article, 2017

, Selection of right studies criteria to foster conclusions. Caveats for metanalysis conducted in sepsis, Heart & Lung: The Journal of Acute and Critical Care, 2017 Journal Article, 2017

, Current challenges in the management of sepsis in ICUs in resource-poor settings and suggestions for the future, Intensive Care Medicine, 2017 Journal Article, 2017

, Research in community-acquired pneumonia: the next steps, Intensive Care Medicine, 2017 Journal Article, 2017

, BreathDx--molecular analysis of exhaled breath as a diagnostic test for ventilator--associated pneumonia: protocol for a European multicentre observational study, BMC Pulmonary Medicine, 2017 Journal Article, 2017

, Antibiotic therapy in the critically ill-expert opinion of the Intensive Care Medicine Scientific Subcommittee of the European Society of Anaesthesiology, European Journal of Anaesthesiology (EJA), 2017 Journal Article, 2017

, Bacterial pneumonia as an influenza complication, Current opinion in infectious diseases, 2017 Journal Article, 2017

, Increased incidence of co-infection in critically ill patients with influenza, Intensive Care Medicine, 2017 Journal Article, 2017

, The dynamics of the pulmonary microbiome during mechanical ventilation in the intensive care unit and the association with occurrence of pneumonia, Thorax, 2017 Journal Article, 2017

, What patient data should be collected in this randomized controlled trial in sepsis?, 2016 Journal Article, 2016

, Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA), World Journal of Emergency Surgery, 2016 Journal Article, 2016

, Endothelial adhesion molecules and multiple organ failure in patients with severe sepsis, Cytokine, 2016 Journal Article, 2016

, The significance of clinical scores and biological markers in disease severity, mortality prediction, and justifying hospital admissions in patients with community-acquired pneumonia, Community Acquired Infection, 2016 Journal Article, 2016

, Is there a continuum between ventilator-associated tracheobronchitis and ventilator-associated pneumonia?, Intensive care medicine, 2016 Journal Article, 2016

, Duration of antibiotic therapy in the intensive care unit, Journal of Thoracic Disease, 2016 Journal Article, 2016

, Determinants of time to death in hospital in critically ill patients around the world, Intensive Care Medicine, 2016 Journal Article, 2016

, Macrolide therapy of pneumonia: is it necessary, and how does it help?, Current opinion in infectious diseases, 2016 Journal Article, 2016

, What"s new in multidrug-resistant pathogens in the ICU?, Annals of intensive care, 2016 Journal Article, 2016

, Impact of Candida spp. isolation in the respiratory tract in patients with intensive care unit-acquired pneumonia, Clinical Microbiology and Infection, 2016 Journal Article, 2016

, New definition of sepsis and septic shock: What does it give us?, Medicina intensiva, 2016 Journal Article, 2016

, Piperacillin population pharmacokinetics in critically ill patients with multiple organ dysfunction syndrome receiving continuous venovenous haemodiafiltration: effect of type of dialysis membrane on dosing requirements, Journal of Antimicrobial Chemotherapy, 2016 Journal Article, 2016

, Finally time for rapid response systems to be well MET in Europe?, Intensive care medicine, 2016 Journal Article, 2016

, Procalcitonin (PCT) levels for ruling-out bacterial coinfection in ICU patients with influenza: a CHAID decision-tree analysis, Journal of Infection, 2016 Journal Article, 2016

, Personalized medicine for ARDS: the 2035 research agenda, Intensive care medicine, 2016 Journal Article, 2016

, ESICM LIVES 2016: part two, Intensive care medicine experimental, 2016 Journal Article, 2016

, Focus on infection and sepsis in intensive care patients., Intensive care medicine, 2016 Journal Article, 2016

, Author's response to:" Harmful effects form one puff of shisha-pen vapor: methodological and interpretational problems in the risk assessment analysis", Tobacco induced diseases, 2016 Journal Article, 2016

, Intracerebral hemorrhage in ICU: is it worth treating?, INTENSIVE CARE MEDICINE EXPERIMENTAL, 2016 Journal Article, 2016

, Collinearity and multivariable analysis: response to comments by Claret et al., Intensive Care Medicine, 2016 Journal Article, 2016

, Evolution over a 15-year period of the clinical characteristics and outcomes of critically ill patients with severe community-acquired pneumonia, Medicina Intensiva (English Edition), 2016 Journal Article, 2016

, Microbial Etiology of Pneumonia: Epidemiology, Diagnosis and Resistance Patterns, International Journal of Molecular Sciences, 2016 Journal Article, 2016

, Coagulopathy in fulminant liver failure with ultimately fatal clot formation, Intensive care medicine, 2016 Journal Article, 2016

, SEPsis REcognition and MAnagement (SEPREMA survey)., Intensive care medicine, 2016 Journal Article, 2016

, Biomarker kinetics in the prediction of VAP diagnosis: results from the BioVAP study, Annals of intensive care, 2016 Journal Article, 2016

O'Connor E, Martin-Loeches I, A blueprint for improving undergraduate education in intensive care medicine, Critical Care, 20, 2016, p212- Journal Article, 2016

, Toward a personalized response approach in sepsis 4.0, Medicina Intensiva, 2016 Journal Article, 2016

, Will all ARDS patients be receiving mechanical ventilation in 2035? Yes, 2016 Journal Article, 2016

, Long term mortality following sepsis, Annals of Translational Medicine, 2016 Journal Article, 2016

, Cortical and subcortical grey matter morphometry for neuroprognostication after cardiac arrest, INTENSIVE CARE MEDICINE EXPERIMENTAL, 2016 Journal Article, 2016

, Neces-SARI-ly?, Intensive Care Med, 2016 Journal Article, 2016

, Epidemiological characteristics, practice of ventilation, and clinical outcome in patients at risk of acute respiratory distress syndrome in intensive care units from 16 countries (PRoVENT): an international, multicentre, prospective study, The Lancet Respiratory Medicine, 2016 Journal Article, 2016

, ESICM LIVES 2016: part three, Intensive care medicine experimental, 2016 Journal Article, 2016

, In the name of ventilator-associated pneumonia prevention: lung microbiota blown away by colistin!, 2015 Journal Article, 2015

, Update on the combination effect of macrolide antibiotics in community-acquired pneumonia, Respiratory investigation, 2015 Journal Article, 2015

, Biomarker Kinetics in VAP, Clinical Pulmonary Medicine, 2015 Journal Article, 2015

, Contrast-enhanced signs of cardiac arrest during CT., Medicina intensiva/Sociedad Espanola de Medicina Intensiva y Unidades Coronarias, 2015 Journal Article, 2015

, Grado de adherencia al tratamiento antiv""rico recomendado durante la pandemia y periodo pospandémico de gripe A (H1N1) pdm09 en 148 unidades de cuidados intensivos espanolas, Medicina Intensiva, 2015 Journal Article, 2015

, Factors associated with misdiagnosis: the usefulness of necropsy, Intensive care medicine experimental, 2015 Journal Article, 2015

, Being overweight is associated with greater survival in ICU patients: results from the intensive care over nations audit, Critical care medicine, 2015 Journal Article, 2015

, Pneumococcal pneumonia coinfection in critically ill patients with influenza a (h1n1) primary viral pneumonia, Intensive care medicine experimental, 2015 Journal Article, 2015

, Degree of adherence to recommended antiviral treatment during the pandemic and post-pandemic periods of influenza A (H1N1) pdm09 in 148 intensive care units in Spain, Medicina Intensiva (English Edition), 2015 Journal Article, 2015

, Incidence and prognosis of ventilator-associated tracheobronchitis (TAVeM): a multicentre, prospective, observational study, The Lancet Respiratory Medicine, 2015 Journal Article, 2015

, Tumor necrosis factor receptor 1 (TNFRI) for ventilator-associated pneumonia diagnosis by cytokine multiplex analysis, Intensive care medicine experimental, 2015 Journal Article, 2015

, Lung health care"what does the future have in store?, The Lancet Respiratory Medicine, 2015 Journal Article, 2015

, Management of severe sepsis: advances, challenges, and current status, Drug design, development and therapy, 2015 Journal Article, 2015

, D-Dimer elevation and adverse outcomes, Journal of thrombosis and thrombolysis, 2015 Journal Article, 2015

, Chromogranin A levels and mortality in patients with severe sepsis, Biomarkers, 2015 Journal Article, 2015

, Impact of non-invasive mechanical ventilation (niv) in critical patients with influenza (H1N1) PDM09, Intensive care medicine experimental, 2015 Journal Article, 2015

, Efficiency of a mechanical device in controlling tracheal cuff pressure in intubated critically ill patients: a randomized controlled study, Annals of intensive care, 2015 Journal Article, 2015

, Meropenem population pharmacokinetics in critically ill patients with septic shock and continuous renal replacement therapy: influence of residual diuresis on dose requirements, Antimicrobial agents and chemotherapy, 2015 Journal Article, 2015

, COPD patients with ventilator-associated pneumonia: implications for management, European Journal of Clinical Microbiology & Infectious Diseases, 2015 Journal Article, 2015

, Resistance patterns and outcomes in intensive care unit (ICU)-acquired pneumonia. Validation of European Centre for Disease Prevention and Control (ECDC) and the Centers for Disease Control and Prevention (CDC) classification of multidrug resistant organisms, Journal of Infection, 2015 Journal Article, 2015

, Regional oxygen saturation index (rSO 2) in brachioradialis and deltoid muscle. Correlation and prognosis in patients with respiratory sepsis, Medicina Intensiva (English Edition), 2015 Journal Article, 2015

, Optimal care and design of the tracheal cuff in the critically ill patient, Annals of intensive care, 2014 Journal Article, 2014

, Oxidative stress in immunocompetent patients with severe community-acquired pneumonia. A pilot study, Medicina Intensiva (English Edition), 2014 Journal Article, 2014

, Assessment of the taxi sector efficiency and profitability based on continuous monitoring and methodology to review fares, Transportation Research Board, Washington, DC, 2014 Journal Article, 2014

, IgA level in plasma as a differential factor for influenza infection in severe viral pneumonia., Journal of clinical virology: the official publication of the Pan American Society for Clinical Virology, 2014 Journal Article, 2014

, DEGREE OF ADHERENCE TO RECOMMENDED ANTIVIRAL TREATMENT DURING THE PANDEMIC AND POST-PANDEMIC PERIODS OF INFLUENZA A (H1N1) PDM09 IN 148 UCIS IN SPAIN, INTENSIVE CARE MEDICINE, 2014 Journal Article, 2014

, Epidemiology, antibiotic therapy and clinical outcomes of healthcare-associated pneumonia in critically ill patients: a Spanish cohort study, Intensive care medicine, 2014 Journal Article, 2014

, Antibiotika senken Mortalität bei Sepsis, Journal Club AINS, 2014 Journal Article, 2014

, Are preoperative oral care bundles needed to prevent postoperative pneumonia?, Intensive care medicine, 2014 Journal Article, 2014

, Treating HSV and CMV reactivations in critically ill patients who are not immunocompromised: pro, 2014 Journal Article, 2014

, Community acquired pneumonia: Genetic variants influencing systemic inflammation, Medicina Intensiva (English Edition), 2014 Journal Article, 2014

, Neumon""a adquirida en la comunidad: variantes génicas implicadas en la inflamación sistémicamación sistémica, Medicina Intensiva, 2014 Journal Article, 2014

, Beta-lactam dosing in critically ill patients with septic shock and continuous renal replacement therapy, Critical Care, 2014 Journal Article, 2014

, Advanced Machine Learning for classification of EEG traits as Parkinson"s biomarker, Frontiers in Neuroinformatics, 2014 Journal Article, 2014

, Innovations that could improve early recognition of ventilator-associated pneumonia, Intensive care medicine, 2014 Journal Article, 2014

, Ventilator-associated tracheobronchitis: where are we now?, Revista Brasileira de terapia intensiva, 2014 Journal Article, 2014

, Predicting treatment failure in patients with community acquired pneumonia: a case-control study, Respiratory research, 2014 Journal Article, 2014

, The volatile metabolic fingerprint of ventilator-associated pneumonia, Intensive care medicine, 2014 Journal Article, 2014

, Risks for multidrug-resistant pathogens in the ICU, Current opinion in critical care, 2014 Journal Article, 2014

, Impact of appropriate antimicrobial treatment on transition from ventilator-associated tracheobronchitis to ventilator-associated pneumonia, Critical Care, 2014 Journal Article, 2014

, Formación en Medicina Intensiva. Un reto a nuestro alcance, Medicina Intensiva, 2014 Journal Article, 2014

, Inflammation and infection in critical care medicine, Mediators of inflammation, 2014 Journal Article, 2014

, Training in Intensive Care Medicine. A challenge within reach, Medicina Intensiva (English Edition), 2014 Journal Article, 2014

, Assessment of the worldwide burden of critical illness: the Intensive Care Over Nations (ICON) audit, The lancet Respiratory medicine, 2014 Journal Article, 2014

, FEASIBILITY OF A PNEUMATIC DEVICE IN CONTROLLING TRACHEAL CUFF PRESSURE IN INTUBATED CRITICALLY ILL PATIENTS, INTENSIVE CARE MEDICINE, 2014 Journal Article, 2014

, Empiric antibiotic treatment reduces mortality in severe sepsis and septic shock from the first hour: results from a guideline-based performance improvement program, Critical care medicine, 2014 Journal Article, 2014

, SEVERE COMMUNITY-ACQUIRED PNEUMONIA (SCAP): 15 YEARS EXPERIENCE IN A SINGLE CENTER, INTENSIVE CARE MEDICINE, 2014 Journal Article, 2014

, Incidence and diagnosis of ventilator-associated tracheobronchitis in the intensive care unit: an international online survey, Critical Care, 2014 Journal Article, 2014

, TRENDS IN INCIDENCE AND HOSPITAL OUTCOMES AMONG PATIENTS WITH SEVERE SEPSIS IN CATALONIA DURING THE 2008-2012 PERIOD, INTENSIVE CARE MEDICINE, 2014 Journal Article, 2014

, FLUID BALANCE AND BIOMARKERS OF ACUTE KIDNEY INJURY, INTENSIVE CARE MEDICINE, 2014 Journal Article, 2014

, Prevalence, risk factors, and mortality for ventilator-associated pneumonia in middle-aged, old, and very old critically ill patients, Critical care medicine, 2014 Journal Article, 2014

, Impact of de-escalation on ICU patients" prognosis, 2014 Journal Article, 2014

, Macrolide-based regimens in absence of bacterial co-infection in critically ill H1N1 patients with primary viral pneumonia, Intensive care medicine, 2013 Journal Article, 2013

, Potentially resistant microorganisms in intubated patients with hospital-acquired pneumonia: the interaction of ecology, shock and risk factors, Intensive care medicine, 2013 Journal Article, 2013

, Genetic Polymorphisms of Systemic Inflammation in Community-acquired Pneumonia, Clinical Pulmonary Medicine, 2013 Journal Article, 2013

, IgM levels in plasma predict outcome in severe pandemic influenza, Journal of Clinical Virology, 2013 Journal Article, 2013

, Evolution over a 15-year period of clinical characteristics and outcomes of critically ill patients with community-acquired bacteremia, Critical care medicine, 2013 Journal Article, 2013

, From ventilator-associated tracheobronchitis to ventilator-associated pneumonia, Reanimation, 2013 Journal Article, 2013

, A week seems to be weak: tailoring duration of antibiotic treatment in Gram-negative ventilator-associated pneumonia, Critical Care, 2013 Journal Article, 2013

, Neumon""a nosocomial, Enfermedades Infecciosas y Microbiolog""a Cl""nica, 2013 Journal Article, 2013

, AZITHROMYCLN DOES NOT AFFECT MORTALITY AMONG PATIENT WITH SEVERE SEPSIS: A PILOT RANDOMIZED CONTROLLED TRIAL, INTENSIVE CARE MEDICINE, 2013 Journal Article, 2013

, Bacteriemia adquirida en la comunidad en pacientes cr""ticamente enfermos, Crit Care Med, 2013 Journal Article, 2013

, GTEI/SEMICYUC Working Group on Bacteremia. Evolution over a 15-year period of clinical characteristics and outcomes of critically ill patients with community-acquired bacteremia, Crit Care Med, 2013 Journal Article, 2013

, Antibiotic Prophylaxis for Ventilator-Associated Pneumonia More Is Less or Less Is More? Response, CHEST, 2013 Journal Article, 2013

, POINT/COUNTERPOINT EDITORIALS, CHEST, 2013 Journal Article, 2013

, Effectiveness of an inspiratory pressure-limited approach to mechanical ventilation in septic patients, European Respiratory Journal, 2013 Journal Article, 2013

, Efficacy of single-dose antibiotic against early-onset pneumonia in comatose patients who are ventilated, CHEST Journal, 2013 Journal Article, 2013

, Correlates of motivation to practice physical activity among students from Portuguese military college, British journal of sports medicine, 2013 Journal Article, 2013

, 'VOLATILE METABOLITE FINGERPRINTS'OF TRACHEAL ASPIRATES DISCRIMINATES PATIENTS WITH VAP FROM CONTROLS, INTENSIVE CARE MEDICINE, 2013 Journal Article, 2013

, Immunological monitoring to prevent and treat sepsis, Critical Care, 2013 Journal Article, 2013

, Acute respiratory distress syndrome: prevention and early recognition, Annals of intensive care, 2013 Journal Article, 2013

, Rationale and study design of provent"an international multicenter observational study on practice of ventilation in critically ill patients without ARDS, J Clin Trials, 2013 Journal Article, 2013

, Nosocomial pneumonia, Enfermedades infecciosas y microbiologia clinica, 2013 Journal Article, 2013

, TISSUE OXYGEN SATURATION LNDEX (RSO2) IN BRACHIORADIALIS (BR)) AND DELTOID LID MUSCLE. CORRELATION AND PROGNOSIS IN PATIENTS WITH RESPIRATORY SEPSIS, INTENSIVE CARE MEDICINE, 2013 Journal Article, 2013

, Uso de oxigenador de membrana extracorpóreo en pacientes con insuficiencia respiratoria aguda grave refractaria en la epidemia de gripe estacional 2010-2011 por influenza A (H1N1) en España, Medicina intensiva, 2012 Journal Article, 2012

, Variants at the promoter of the interleukin-6 gene are associated with severity and outcome of pneumococcal community-acquired pneumonia, Intensive care medicine, 2012 Journal Article, 2012

, The Complex Interaction between Sepsis and Lung Injury, Annual Update in Intensive Care and Emergency Medicine 2012, 2012 Journal Article, 2012

, Educação F""sica: uma disciplina, diferentes perspetivas. Implicações práticas, Boletim SPEF, 2012 Journal Article, 2012

, Intubated patients developing tracheobronchitis or pneumonia have distinctive complement system gene expression signatures in the pre-infection period: a pilot study, Medicina Intensiva (English Edition), 2012 Journal Article, 2012

, Severity and outcomes of hospitalised community-acquired pneumonia in COPD patients, European Respiratory Journal, 2012 Journal Article, 2012

, Tracheostomy And Risk Of Ventilator-Associated Pneumonia At Latin American Intensive Care Units (icus), D62. NOSOCOMIAL INFECTIONS: BACTERIOLOGY, DRUG RESISTANCE, AND OUTCOMES, 2012 Journal Article, 2012

, Extracorporeal lung support in patients with severe respiratory failure secondary to the 2010--2011 winter seasonal outbreak of influenza A (H1N1) in Spain, Medicina Intensiva (English Edition), 2012 Journal Article, 2012

, Interleukin-6 is a potential biomarker for severe pandemic H1N1 influenza A infection, PloS one, 2012 Journal Article, 2012

, Recommendations of the Infectious Diseases Work Group (GTEI) of the Spanish Society of Intensive and Critical Care Medicine and Coronary Units (SEMICYUC) and the Infections in Critically Ill Patients Study Group (GEIPC) of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) for the diagnosis and treatment of influenza A/H1N1 in seriously ill adults admitted to the intensive care unit, Medicina Intensiva (English Edition), 2012 Journal Article, 2012

, Situación actual de la realización de fibrobroncoscopias en los Servicios de Medicina Intensiva, Medicina intensiva, 2012 Journal Article, 2012

, Critical COPD respiratory illness is linked to increased transcriptomic activity of neutrophil proteases genes, BMC research notes, 2012 Journal Article, 2012

, Impact Of Time To Broad-Spectrum Antibiotic On Mortality Of Severe Sepsis And Septic Shock. Results From The Surviving Sepsis Campaign, C24. THIS CAN BE DONE BETTER: QUALITY, SAFETY AND PROCESS IMPROVEMENT IN CRITICAL CARE, 2012 Journal Article, 2012

, Los pacientes intubados que presentan traqueobronquitis o neumon""a tienen patrones distintivos de expresión genética del sistema del complemento en el per""odo previo a la infección: un estudio piloto, Medicina Intensiva, 2012 Journal Article, 2012

, PMC3603106., Intensive Care Med, 2012 Journal Article, 2012

, Overtreating or underdiagnosing invasive pulmonary aspergillosis (IPA) in critically ill H1N1 patients: who is right?, 2012 Journal Article, 2012

, Current status of fiberoptic bronchoscopy in intensive care medicine, Medicina Intensiva (English Edition), 2012 Journal Article, 2012

, Severity assessment tools in ICU patients with 2009 Influenza A (H1N1) pneumonia, Clinical microbiology and infection, 2012 Journal Article, 2012

, Viral infection is associated with an increased proinflammatory response in chronic obstructive pulmonary disease, Viral immunology, 2012 Journal Article, 2012

, Corticosteroid therapy in patients with primary viral pneumonia due to pandemic (H1N1) 2009 influenza, Journal of Infection, 2012 Journal Article, 2012

, Recomendaciones del Grupo de Trabajo Enfermedades Infecciosas (GTEI) de la Sociedad Española de Medicina Intensiva, Cr""tica y Unidades Coronarias (SEMICYUC) y el Grupo de Estudio de Infecciones en el Paciente Cr""tico (GEIPC) de la Sociedad Española de Enfermedades Infecciosas y Microbiolog""a cl""nica (SEIMC) para el diagnóstico y tratamiento de la gripe A/H1N1 en pacientes adultos graves hospitalizados en las Unidades de Cuidados Intensivos, Medicina intensiva, 2012 Journal Article, 2012

, Antibiotic prescription patterns in the empiric therapy of severe sepsis: combination of antimicrobials with different mechanisms of action reduces mortality, Critical Care, 2012 Journal Article, 2012

, EFFECTIVENESS OF INSPIRATORY PRESSURE-LIMITED APPROACH TO MECHANICAL VENTILATION IN SEPTIC PATIENTS, INTENSIVE CARE MEDICINE, 2012 Journal Article, 2012

, Severe Pandemic (H1N1) Influenza A Infection, Clinical Pulmonary Medicine, 2011 Journal Article, 2011

, Severe 2009 A/H1N1v influenza in pregnant women in Spain, Critical care medicine, 2011 Journal Article, 2011

, Ventilator Associated Tracheobronchitis, Bronchitis, 2011 Journal Article, 2011

, Bacteremia is an independent risk factor for mortality in nosocomial pneumonia: a prospective and observational multicenter study, Critical care, 2011 Journal Article, 2011

, Use of early corticosteroid therapy on ICU admission in patients affected by severe pandemic (H1N1) v influenza A infection, Intensive care medicine, 2011 Journal Article, 2011

, First influenza season after the 2009 pandemic influenza: report of the first 300 ICU admissions in Spain, Medicina Intensiva (English Edition), 2011 Journal Article, 2011

, Community-acquired respiratory coinfection in critically ill patients with pandemic 2009 influenza A (H1N1) virus, CHEST Journal, 2011 Journal Article, 2011

, Primera epidemia de gripe estacional después de la pandemia por gripe A en 2009: descripción de los primeros 300 ingresos en UCI españolas, Medicina Intensiva, 2011 Journal Article, 2011

, ESICM H1N1 Registry Contributors: Use of early corticosteroid therapy on ICU admission in patients affected by severe pandemic (H1N1) v influenza A infection, Intensive Care Med, 2011 Journal Article, 2011

, Direct association between pharyngeal viral secretion and host cytokine response in severe pandemic influenza, BMC infectious diseases, 2011 Journal Article, 2011

, Acute kidney injury in critical ill patients affected by influenza A (H1N1) virus infection, Critical Care, 2011 Journal Article, 2011

, Determinants of prescription and choice of empirical therapy for hospital-acquired and ventilator-associated pneumonia, European Respiratory Journal, 2011 Journal Article, 2011

, Impact of early oseltamivir treatment on outcome in critically ill patients with 2009 pandemic influenza A, Journal of antimicrobial chemotherapy, 2011 Journal Article, 2011

, Patient to nurse ratio and risk of ventilator-associated pneumonia in critically ill patients, American Journal of Critical Care, 2011 Journal Article, 2011

, PANDEMIC 2009 INFLUENZA A (H1N1) AND AN/H1N1 2010-11 SEASONAL OUTBREAK: MORTALITY AND RISK FACTORS IN CRITICALLY ILL PATIENTS, INTENSIVE CARE MEDICINE, 2011 Journal Article, 2011

, Imbalanced pro-and anti-Th17 responses (IL-17/granulocyte colony-stimulating factor) predict fatal outcome in 2009 pandemic influenza, Critical Care, 2011 Journal Article, 2011

, Impact of obesity in patients infected with 2009 influenza A (H1N1), CHEST Journal, 2011 Journal Article, 2011

, Pandemic and post-pandemic influenza A (H1N1) infection in critically ill patients, Critical care, 2011 Journal Article, 2011

, A new approach to ventilator-associated pneumonia based on the PIRO system, Annual Update in Intensive Care and Emergency Medicine 2011, 2011 Journal Article, 2011

, Current Key Points in Management for Severe Community-Acquired Pneumonia, Current Respiratory Medicine Reviews, 2011 Journal Article, 2011

, Severe pandemic (H1N1) v influenza A infection: report on the first deaths in Spain, Respirology, 2011 Journal Article, 2011

, Mortality and regional oxygen saturation index in septic shock patients: a pilot study, Journal of Trauma and Acute Care Surgery, 2011 Journal Article, 2011

, Traqueobronquite associada ao ventilador: onde nos encontramos?., Revista Brasileira de Terapia Intensiva, 2010 Journal Article, 2010

, Host adaptive immunity deficiency in severe pandemic influenza, Critical Care, 2010 Journal Article, 2010

, Clinical characteristics in a cohort of critically ill patients infected with pandemic influenza A (H1N1) V: The ESiCM H1N1 registry, INTENSIVE CARE MEDICINE, 2010 Journal Article, 2010

, Genetic variability in the severity and outcome of community-acquired pneumonia, Respiratory medicine, 2010 Journal Article, 2010

, What is new in ventilator-associated tracheobronchitis?, Clinical Pulmonary Medicine, 2010 Journal Article, 2010

, PULMONARY VERSUS NON PULMONARY PRESENTATION IN SEVERE PANDEMIC INFLUENZA A (H1N1) V, INTENSIVE CARE MEDICINE, 2010 Journal Article, 2010

, HOSPITAL ACQUIRED PNEUMONIA AFTER LUNG RESECTION SURGERY DISPLAYS CHARACTERISTIC CYTOKINE PROFILES, INTENSIVE CARE MEDICINE, 2010 Journal Article, 2010

, PIRO-CAP IN PANDEMIC INFLUENZA A (H1N1) V: RESULTS OF THE ESICM INFLUENZA A (H1N1) V REGISTRY, INTENSIVE CARE MEDICINE, 2010 Journal Article, 2010

, Curb-65 in pandemic influenza a (H1N1) v: Results of the esicm influenza a (H1N1) v registry, Intensive Care Medicine, 2010 Journal Article, 2010

, Cytokine profiles of suction pulmonary secretions from children infected with pandemic influenza A (H1N1) 2009 Response, CRITICAL CARE, 2010 Journal Article, 2010

, Combination antibiotic therapy with macrolides improves survival in intubated patients with community-acquired pneumonia, Intensive care medicine, 2010 Journal Article, 2010

, COMPARATIVE STUDY OF PATIENTS ADMITTED IN INTENSIVE CARE WITH INFLUENZA A (H1N1) V. COMPARATIVE STUDY OF EUROPE VERSUS LATIN AMERICA. RESULTS OF THE ESICM INFLUENZA A (H1N1) V REGISTRY, INTENSIVE CARE MEDICINE, 2010 Journal Article, 2010

, Determinants of choice and prescription patterns in empiric antibiotic therapy for HAP/VAP, European Respiratory Journal, 2010 Journal Article, 2010

, BACTERIAL CO-INFECTION IN CRITICALLY ILL PATIENTS INFECTED WITH PANDEMIC (H1N1) V INFLUENZA A INFECTION, INTENSIVE CARE MEDICINE, 2010 Journal Article, 2010

, Proinflamatory and Autoimmune-like Cytokines Profiles in Severe Pandemic Influenza H1N1 Disease, Clinical Immunology, 2010 Journal Article, 2010

, Reply to Westley and Chan and to Shih et al., Intensive Care Medicine, 2010 Journal Article, 2010

, CLINICAL CHARACTERISTICS IN A COHORT OF CRITICALLY ILL PATIENTS INFECTED WITH PANDEMIC INFLUENZA A (H1N1) V RECEIVING EXTRACORPOREAL MEMBRANE OXIGENATION (ECMO) THE ESICM H1N1 REGISTRY, INTENSIVE CARE MEDICINE, 2010 Journal Article, 2010

, MORTALITY ASSOCIATED TO SEVERE PANDEMIC H1N1 INFLUENZA A INFECTION, INTENSIVE CARE MEDICINE, 2010 Journal Article, 2010

, Use of corticosteroid therapy in patients affected by severe pandemic (H1N1) V influenza A infection, INTENSIVE CARE MEDICINE, 2010 Journal Article, 2010

, Community-Acquired Respiratory Coinfection in Critically Ill Patients Infected With Pandemic 2009 Influenza A (H1N1) Virus Infection, 2010 Journal Article, 2010

, BACTERIAL PNEUMONIA COMPLICATING INFLUENZA A (H1N1) V VIRAL PNEUMONIA: RESULTS OF THE ESICM INFLUENZA A (H1N1) V REGISTRY, INTENSIVE CARE MEDICINE, 2010 Journal Article, 2010

, Community-Acquired Pneumonia Intensive Care Units (CAPUCI) Study Inves tigators. Mortality in ICU patients with bacterial community-acquired pneumonia: when antibiotics are not enough, Intensive Care Med, 2009 Journal Article, 2009

, Spectrum of practice in the diagnosis of nosocomial pneumonia in patients requiring mechanical ventilation in European intensive care units, Critical care medicine, 2009 Journal Article, 2009

, Management of Sepsis: The PIRO Approach, 2009 Journal Article, 2009

, Community-Acquired Pneumonia Management Based on the PIRO System. A New Therapeutic Paradigm, Management of Sepsis: The PIRO Approach, 2009 Journal Article, 2009

, Protocolo de manejo de la Insuficiencia Respiratoria Aguda Grave en pacientes con neumon""a viral primaria por el nuevo virus de la Gripe A (H1N1) en UCI, Science, 2009 Journal Article, 2009

, Th1 and Th17 hypercytokinemia as early host response signature in severe pandemic influenza, Critical Care, 2009 Journal Article, 2009

, SEVERE COMMUNITY-ACQUIRED PNEUMONIA IN EUROPE: RESULTS FROM EU-VAP/CAP STUDY, INTENSIVE CARE MEDICINE, 2009 Journal Article, 2009

, Mortality in ICU patients with bacterial community-acquired pneumonia: when antibiotics are not enough, Intensive care medicine, 2009 Journal Article, 2009

, Effect of the IL-6 promoter polymorphism-174 G/C on risk and outcome of pneumonia, Critical Care, 2008 Journal Article, 2008

, Combination antibiotic therapy improves survival in patients with community-acquired pneumonia and shock, Critical care medicine, 2007 Journal Article, 2007

, Lens transmission and autofluorescence in renal disease, Ophthalmic research, 1988 Journal Article, 1988

B.R. Ballinger, J. Feely, Antidepressants, British Medical Journal , 286, 1983, p1885 - 1887 Journal Article, 1983

, Effects of biomechanics and of dressings with calcium hydroxide, 1% paramonochlorophenol or a combination of both on reduction of microbial flora of infected root canals, Ars curandi em odontologia, 1979 Journal Article, 1979

, Efeitos da biomec"anica e de curativos de demora com hidróxido de cálcio, paramonoclorofenol a 1% ou associação de ambos na redução da flora microbiana dos canais radiculares infectados, ARS Cvrandy em Odontologia, 1979 Journal Article, 1979

Non-Peer-Reviewed Publications

martin-loeches , ESICM/ESCMID task force on practical management of invasive candidiasis in critically ill patients, ICM, 2019, p10.1007/s00134-019-05599-w Journal Article, 2019

Research Expertise

Projects

  • Title
    • ENIRRI
  • Summary
    • pneumonia in ICU
  • Funding Agency
    • EU

Keywords

ARDS; COMMUNITY ACQUIRED PNEUMONIA; NOSOCOMIAL PNEUMONIA; SEPSIS; VENTILATOR-ASSOCIATED PNEUMONIA

Recognition

Representations

Strategic Advisor under the Group of Experts (SAGE) on Influenza for World Health Organization (WHO). 2008

Chair for COBATRICE at the ESICM 2018

Secretary of Group 02.01 - Acute Critical Care by ERS members of your group. 2019

Executive Member of the Education and Training Committee for the European Respiratory Society. Respiratory Critical Care HERMES program. 2016

External Examiner European Diploma Intensive Care Medicine 2018

Awards and Honours

Summa Cum laude 2008

Clinical Excellence award Spanish Society of Intensive Care Medicine 2006

Senior investigator for the European society of Intensive Care Medicine 2018