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Professor David Gallagher
Clinical Professor, Clinical Medicine

Publications and Further Research Outputs

Peer-Reviewed Publications

O'Shea R, Clarke R, Berkley E, Giffney C, Farrell M, O'Donovan E, Gallagher DJ., Next generation sequencing is informing phenotype: a TP53 example., Familial cancer, 17, (1), 2018, p123-128 Journal Article, 2018 DOI

Saya S, Killick E, Thomas S, Taylor N, Bancroft EK, Rothwell J, Benafif S, Dias A, Mikropoulos C, Pope J, Chamberlain A, Gunapala R, SIGNIFY Study Steering Committee, Izatt L, Side L, Walker L, Tomkins S, Cook J, Barwell J, Wiles V, Limb L, Eccles D, Leach MO, Shanley S, Gilbert FJ, Hanson H, Gallagher D, Rajashanker B, Whitehouse RW, Koh DM, Sohaib SA, Evans DG, Eeles RA., Baseline results from the UK SIGNIFY study: a whole-body MRI screening study in TP53 mutation carriers and matched controls., Familial cancer, 16, (3), 2017, p433-440 Journal Article, 2017 DOI

McVeigh TP, Cody N, Carroll C, Duff M, Farrell M, Bradley L, Gallagher D, McDevitt T, Green AJ., Recurrent large genomic rearrangements in BRCA1 and BRCA2 in an Irish case series., Cancer genetics, 214-215, 2017, p1-8 Journal Article, 2017 DOI

Gogarty DS, Farrell MP, Gallagher DJ., Genetic testing and interpretive complexity: a BRCA1 gene mutation example., Ir J Med Sci, 185, (4), 2016, p955-957 Journal Article, 2016 DOI

McVeigh TP, Sweeney KJ, Kerin MJ, Gallagher DJ., A qualitative analysis of the attitudes of Irish patients towards participation in genetic-based research., Ir J Med Sci, 185, (4), 2016, p825-831 Journal Article, 2016 DOI

Gleeson J, Gallagher D., Diagnosing Lynch Syndrome., Irish medical journal, 109, (10), 2016, p487 Journal Article, 2016 DOI

McVeigh TP, Duff M, Carroll C, O'Shea R, Bradley L, Farrell M, Gallagher DJ, Clabby C, Green AJ., MUTYH-Associated Polyposis: The Irish Experience>., Irish medical journal, 109, (10), 2016, p485 Journal Article, 2016 DOI

Sharma S, Barry M, Gallagher DJ, Kell M, Sacchini V., An overview of triple negative breast cancer for surgical oncologists., Surgical oncology, 24, (3), 2015, p276-283 Journal Article, 2015 DOI

Sullivan J, Kopp R, Stratton K, Manschreck C, Corines M, Rau-Murthy R, Hayes J, Lincon A, Ashraf A, Thomas T, Schrader K, Gallagher D, Hamilton R, Scher H, Lilja H, Scardino P, Eastham J, Offit K, Vijai J, Klein RJ., An analysis of the association between prostate cancer risk loci, PSA levels, disease aggressiveness and disease-specific mortality., British journal of cancer, 113, (1), 2015, p166-172 Journal Article, 2015 DOI

Bancroft EK, Page EC, Castro E, Lilja H, Vickers A, Sjoberg D, Assel M, Foster CS, Mitchell G, Drew K, Mæhle L, Axcrona K, Evans DG, Bulman B, Eccles D, McBride D, van Asperen C, Vasen H, Kiemeney LA, Ringelberg J, Cybulski C, Wokolorczyk D, Selkirk C, Hulick PJ, Bojesen A, Skytte AB, Lam J, Taylor L, Oldenburg R, Cremers R, Verhaegh G, van Zelst-Stams WA, Oosterwijk JC, Blanco I, Salinas M, Cook J, Rosario DJ, Buys S, Conner T, Ausems MG, Ong KR, Hoffman J, Domchek S, Powers J, Teixeira MR, Maia S, Foulkes WD, Taherian N, Ruijs M, Helderman-van den Enden AT, Izatt L, Davidson R, Adank MA, Walker L, Schmutzler R, Tucker K, Kirk J, Hodgson S, Harris M, Douglas F, Lindeman GJ, Zgajnar J, Tischkowitz M, Clowes VE, Susman R, Ramón y Cajal T, Patcher N, Gadea N, Spigelman A, van Os T, Liljegren A, Side L, Brewer C, Brady AF, Donaldson A, Stefansdottir V, Friedman E, Chen-Shtoyerman R, Amor DJ, Copakova L, Barwell J, Giri VN, Murthy V, Nicolai N, Teo SH, Greenhalgh L, Strom S, Henderson A, McGrath J, Gallagher D, Aaronson N, Ardern-Jones A, Bangma C, Dearnaley D, Costello P, Eyfjord J, Rothwell J, Falconer A, Gronberg H, Hamdy FC, Johannsson O, Khoo V, Kote-Jarai Z, Lubinski J, Axcrona U, Melia J, McKinley J, Mitra AV, Moynihan C, Rennert G, Suri M, Wilson P, Killick E, IMPACT Collaborators, Moss S, Eeles RA., Targeted prostate cancer screening in BRCA1 and BRCA2 mutation carriers: results from the initial screening round of the IMPACT study., European urology, 66, (3), 2014, p489-499 Journal Article, 2014 DOI

Gallagher DJ, Vijai J, Hamilton RJ, Ostrovnaya I, Iyer G, Garcia-Grossman IR, Kim PH, Przybylo JA, Alanee S, Riches JC, Regazzi AM, Milowsky MI, Offit K, Bajorin DF., Germline single nucleotide polymorphisms associated with response of urothelial carcinoma to platinum-based therapy: the role of the host., Annals of oncology : official journal of the European Society for Medical Oncology, 24, (9), 2013, p2414-2421 Journal Article, 2013 DOI

Farrell MP, Hughes DJ, Drost M, Wallace AJ, Cummins RJ, Fletcher TA, Meany MA, Kay EW, de Wind N, Power DG, Andrews EJ, Green AJ, Gallagher DJ., Multivariate analysis of MLH1 c.1664T>C (p.Leu555Pro) mismatch repair gene variant demonstrates its pathogenicity., Familial cancer, 12, (4), 2013, p741-747 Journal Article, 2013 DOI

Bambury RM, Gallagher DJ., Prostate cancer: germline prediction for a commonly variable malignancy., BJU international, 110, (11 pt c), 2012, pE809-18 Journal Article, 2012 DOI

Gallagher DJ, Cronin AM, Milowsky MI, Morris MJ, Bhatia J, Scardino PT, Eastham JA, Offit K, Robson ME., Germline BRCA mutation does not prevent response to taxane-based therapy for the treatment of castration-resistant prostate cancer., BJU international, 109, (5), 2012, p713-719 Journal Article, 2012 DOI

Tickoo SK, Milowsky MI, Dhar N, Dudas ME, Gallagher DJ, Al-Ahmadie H, Gopalan A, Fine SW, Ishill N, Bajorin DF, Reuter VE., Hypoxia-inducible factor and mammalian target of rapamycin pathway markers in urothelial carcinoma of the bladder: possible therapeutic implications., BJU international, 107, (5), 2011, p844-849 Journal Article, 2011 DOI

Gallagher DJ, Konner JA, Bell-McGuinn KM, Bhatia J, Sabbatini P, Aghajanian CA, Offit K, Barakat RR, Spriggs DR, Kauff ND., Survival in epithelial ovarian cancer: a multivariate analysis incorporating BRCA mutation status and platinum sensitivity., Annals of oncology : official journal of the European Society for Medical Oncology, 22, (5), 2011, p1127-1132 Journal Article, 2011 DOI

Gallagher DJ, Al-Ahmadie H, Ostrovnaya I, Gerst SR, Regazzi A, Garcia-Grossman I, Riches J, Gounder SK, Flaherty AM, Trout A, Milowsky MI, Bajorin DF., Sunitinib in urothelial cancer: clinical, pharmacokinetic, and immunohistochemical study of predictors of response., European urology, 60, (2), 2011, p344-349 Journal Article, 2011 DOI

Gallagher DJ, Kemeny N., Metastatic colorectal cancer: from improved survival to potential cure., Oncology, 78, (3-4), 2010, p237-248 Journal Article, 2010 DOI

Stadler ZK, Gallagher DJ, Thom P, Offit K., Genome-wide association studies of cancer: principles and potential utility., Oncology (Williston Park, N.Y.), 24, (7), 2010, p629-637 Journal Article, 2010 DOI

Gallagher DJ, Kemeny N., Improving response and outcomes for patients with liver-limited metastatic colorectal cancer., Clinical colorectal cancer, 9 Suppl 1, 2010, pS36-43 Journal Article, 2010 DOI

Gallagher DJ, Vijai J, Cronin AM, Bhatia J, Vickers AJ, Gaudet MM, Fine S, Reuter V, Scher HI, Halldén C, Dutra-Clarke A, Klein RJ, Scardino PT, Eastham JA, Lilja H, Kirchhoff T, Offit K., Susceptibility loci associated with prostate cancer progression and mortality., Clinical cancer research : an official journal of the American Association for Cancer Research, 16, (10), 2010, p2819-2832 Journal Article, 2010 DOI

Gallagher DJ, Feifer A, Coleman JA., Genitourinary cancer predisposition syndromes., Hematology/oncology clinics of North America, 24, (5), 2010, p861-883 Journal Article, 2010 DOI

Gallagher DJ, Riches J, Bajorin DF., False elevation of human chorionic gonadotropin in a patient with testicular cancer., Nature reviews. Urology, 7, (4), 2010, p230-233 Journal Article, 2010 DOI

Gallagher DJ, Smith JD, Offit K, Stadler ZK., Diagnosing hereditary colorectal cancer., Clinical colorectal cancer, 9, (4), 2010, p205-211 Journal Article, 2010 DOI

Gallagher DJ, Milowsky MI, Gerst SR, Ishill N, Riches J, Regazzi A, Boyle MG, Trout A, Flaherty AM, Bajorin DF., Phase II study of sunitinib in patients with metastatic urothelial cancer., Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 28, (8), 2010, p1373-1379 Journal Article, 2010 DOI

Gallagher DJ, Gaudet MM, Pal P, Kirchhoff T, Balistreri L, Vora K, Bhatia J, Stadler Z, Fine SW, Reuter V, Zelefsky M, Morris MJ, Scher HI, Klein RJ, Norton L, Eastham JA, Scardino PT, Robson ME, Offit K., Germline BRCA mutations denote a clinicopathologic subset of prostate cancer., Clinical cancer research : an official journal of the American Association for Cancer Research, 16, (7), 2010, p2115-2121 Journal Article, 2010 DOI

Gallagher DJ, Milowsky MI, Ishill N, Trout A, Boyle MG, Riches J, Fleisher M, Bajorin DF., Detection of circulating tumor cells in patients with urothelial cancer., Annals of oncology : official journal of the European Society for Medical Oncology, 20, (2), 2009, p305-308 Journal Article, 2009 DOI

Gallagher D, Kemeny N., Treatment of patients with colorectal cancer: emphasis on liver metastases., Expert opinion on pharmacotherapy, 10, (1), 2009, p109-124 Journal Article, 2009 DOI

Gallagher DJ, Kemeny NE., Colorectal hepatic metastases: adjuvant chemotherapy and survival., Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 27, (20), 2009, pe18-9; author reply e20-1 Journal Article, 2009 DOI

Gallagher DJ, Libby DM, Kemeny N., Elevated carcinoembryonic antigen and sarcoidosis masquerading as metastatic colon cancer., Clinical colorectal cancer, 8, (3), 2009, p172-174 Journal Article, 2009 DOI

Gallagher DJ, Milowsky MI, Iasonos A, Maluf FC, Russo P, Dalbagni G, Donat MS, Boyle MG, Zheng J, Riches J, Bajorin DF., Sequential adjuvant chemotherapy after surgical resection of high-risk urothelial carcinoma., Cancer, 115, (22), 2009, p5193-5201 Journal Article, 2009 DOI

Gallagher DJ, Zheng J, Capanu M, Haviland D, Paty P, Dematteo RP, D'Angelica M, Fong Y, Jarnagin WR, Allen PJ, Kemeny N., Response to neoadjuvant chemotherapy does not predict overall survival for patients with synchronous colorectal hepatic metastases., Annals of surgical oncology, 16, (7), 2009, p1844-1851 Journal Article, 2009 DOI

Gallagher DJ, Bajorin DF., Neoadjuvant chemotherapy for the treatment of muscle-invasive bladder cancer: argument in favor., Nature clinical practice. Urology, 5, (9), 2008, p484-485 Journal Article, 2008 DOI

Gallagher DJ, Milowsky MI, Bajorin DF., Advanced bladder cancer: status of first-line chemotherapy and the search for active agents in the second-line setting., Cancer, 113, (6), 2008, p1284-1293 Journal Article, 2008 DOI

Gallagher DJ, Kemeny N., Second-line management of metastatic colorectal cancer., Clinical colorectal cancer, 7, (1), 2008, p25-32 Journal Article, 2008 DOI

Management of mutation negative patients in, Hereditary Gynecological Cancer: Risk, Prevention, and Management, 2008, [Gallagher DJ, Kauff N.] Book Chapter, 2008

Gallagher DJ, Duffy A, McCaffrey J., Wilms' tumour in adults: a case report and review of the literature., Ir J Med Sci, 176, (1), 2007, p49-51 Journal Article, 2007 DOI

Gallagher DJ, Capanu M, Raggio G, Kemeny N., Hepatic arterial infusion plus systemic irinotecan in patients with unresectable hepatic metastases from colorectal cancer previously treated with systemic oxaliplatin: a retrospective analysis., Annals of oncology : official journal of the European Society for Medical Oncology, 18, (12), 2007, p1995-1999 Journal Article, 2007 DOI

Recognition

Representations

National Cancer Control Programme Executive Committee 2015-present

Bobby Bastow Cancer Genetics Foundation Chair 2014-present

Reviewer for New England Journal of Medicine 2016

Reviewer for Journal of Clinical Oncology 2012-2017

Awards and Honours

. ASCO/AACR/FECS Methods in Clinical Cancer Research Workshop (My registrar) 2019

American Society of Clinical Oncology Merit Award Annual Meeting 2010

American Society of Clinical Oncology Merit Award Genitourinary Symposium 2010

American Society of Clinical Oncology Merit Award Gastrointestinal Symposium 2010

American Association of Cancer Research Molecular Biology Workshop 2009

Broad Insititute Genetics of Complex Disorders Workshop 2008

Goldstein Award MSKCC Prevention and Population Research - $50,000 2008

. ASCO/AACR/FECS Methods in Clinical Cancer Research Workshop 2007

. Irish Society of Medical Oncology Scholarship to MSKCC 2006

. University College Dublin Scholarship to University of Pennsylvania 1998

Memberships

FRCPI 2010 – 2019

Irish Society of Medical Oncology 2010 – 2019

Cancer Trials Ireland 2010 – 2019

American Society of Clinincal Oncology 2005 – 2019

European Society of Medical Oncology 2010 – 2019

PRACTICAL: The PRostate cancer AssoCiation Group To Investigate Cancer Associated aLterations in the genome 2011 – 2019

COGS: The Collaborative Ovarian, prostate, and breast Gene environment Study 2011 – 2019

CIMBA BRCA1/2 mutation carrier consortium 2013 – 2019