Biography
Dr Linda O'Neill is a Postdoctoral Researcher with the Trinity Exercise Oncology Research Group. She is a registered physiotherapist and member of the Irish Society of Chartered Physiotherapists (ISCP). She completed her PhD in 2018 which investigated the efficacy of multidisciplinary rehabilitation in oesophago-gastric cancer survivorship. She also holds a Bachelor of Science (BSc.) in Physiotherapy (RCSI), a Masters (MSc.) in Respiratory Physiotherapy (TCD), and a Post-graduate Certificate in Statistics (TCD).
She has a keen research interest in exercise oncology, in particular exercise in cancer survivorship. Her work has been widely published and she has presented at conferences both nationally and internationally. She currently works as a Project Manager on the HRB/MRCG funded Preoperative Exercise to Improve Fitness in Patients Undergoing Complex Surgery for Cancer of the Lung or Oesophagus (PRE-HIIT) trial and the HRB funded Rehabilitation Strategies following Oesophago-gastric and Hepatopancreaticobiliary Cancer (ReStORe II) trial. Recently, she has become very involved in trial methodology research, and currently leads an embedded SWAT in the ReStORe II trial. She is a member of the HRB-TMRN, member of the NIHR-TMRP Trial Conduct Working Group, and is currently co-lead of the TMRP Trial Conduct Working Group-Retention Topic Group
Professionally she has held a number of clinical and educational roles. Clinically she has gained experience in a variety of areas including care of the elderly, rheumatology, cardiorespiratory, and oncology. In recent years she has contributed to undergraduate and post graduate teaching at Trinity College Dublin and Singapore Institute of Technology. She has also previously worked as a Special Lecturer/ Clinical Tutor on the Professional Masters in Physiotherapy Programme at University College Dublin. She is an active member of the ISCP, and is currently the secretary to the ISCP Chartered Physiotherapists in Oncology and Palliative Care Clinical Interest Group.
Publications and Further Research Outputs
Peer-Reviewed Publications
REYNOLDS SA., O'CONNOR L., McGEE A., QUINN KILCOYNE A., CONNOLLY A., MOCKLER D., GUINAN E., O'NEILL L, Recruitment rates and strategies in exercise trials in cancer survivorship: a systematic review, Journal of Cancer Survivorship, 2023
Brennan, L. Sheill, G. O'Neill, L, O'Connor, L, Smyth, E. Guinan, E, Physical Therapists in Oncology Settings: Experiences in Delivering Cancer Rehabilitation Services, Barriers to Care, and Service Development Needs, Physical Therapy, 2022
Brennan, L., Sadeghi, F., O'Neill, L., Guinan, E., Smyth, L. Sheill, G., Smyth, E., Doyle, S.L., Timon, C., Connolly, D., O'Sullivan, J., Reynolds, J.V., and Hussey, J., Telehealth Delivery of a Multi-Disciplinary Rehabilitation Programme for Upper Gastro-Intestinal Cancer: ReStOre@Home Feasibility Study, Cancers, 2022
Grainne Sheill, Emer Guinan, Linda O'Neill, Emily Smyth, Charles Normand, Suzanne L. Doyle, Sarah Moore, John Newell, Grainne McDermott, Ronan Ryan, John V. Reynolds, Juliette Hussey, Prehabilitation during a pandemic: preoperative exercise to improve fitness in patients undergoing complex surgery for cancer of the lung or oesophagus, the PRE-HIIT trial: an updated study protocol, HRB Open Research, 4, 2021, p4
O'Connor, L., Smyth, E., Bennett, A.E.. Smith, V., O'Neill, L., Reynolds, J.V.,. Hussey, J., Guinan, E.M., Identifying outcomes reported in exercise interventions in oesophagogastric cancer survivors: a systematic review, BMC Cancer, 21, (586), 2021, p1-9
Kennedy, S.A., Annett, S.L., Dunne, M.R., Boland, F., O'Neill, L.M., Guinan, E.M., Doyle, S.L., Foley, E.K., Elliott, J.A., Murphy, C.F., Bennett, A.E., Carey, M., Hillary, D., Robson, T., Reynolds, J.V., Hussey, J., O'Sullivan, J.N., Effect of the Rehabilitation Program, ReStOre, on Serum Biomarkers in a Randomized Control Trial of Esophagogastric Cancer Survivors, Frontiers in Oncology, 11, (669078), 2021, p1-11
Bennett, A.E., O'Neill, L., Connolly, D., Guinan, E., Boland, L., Doyle, S., O'Sullivan, J., Reynolds, J.V., Hussey, J., Perspectives of Esophageal Cancer Survivors on Diagnosis, Treatment, and Recovery., Cancers, 13, (1), 2021, p1-12
B Alkhaffaf, A Metryka, J M Blazeby, A -M Glenny, A Adeyeye, P M Costa, I Diez del Val, S S Gisbertz, A Guner, S Law, H -J Lee, Z Li, K Nakada, D Reim, P Vorwald, G L Baiocchi, W Allum, M A Chaudry, E A Griffiths, P R Williamson, I A Bruce, on behalf of the GASTROS International Working Group, Core outcome set for surgical trials in gastric cancer (GASTROS study): international patient and healthcare professional consensus., British Journal of Surgery, 2021
ALKHAFFAF B., BLAZEBY JM, ET AL AND ON BEHALF OF THE GASTROS INTERNATIONAL WORKING GROUP, Methods for conducting international Delphi surveys to optimise global participation in core outcome set development: a case study in gastric cancer informed by a comprehensive literature review, Trials, 2021, phttps://doi.org/10.1186/s13063
Sheill G., Hennessy M., O'Neill L., Reynolds S., Towns J., Gill M., Guinan E., Exercise and chronic health conditions in the community: A qualitative Study of Patients and Fitness instructors, Health and Social Care in the Community, 2021
Alkhaffaf B, Metryka A, Blazeby JM, Glenny A-M, Williamson PR, Bruce IA, et al, How are trial outcomes prioritised by stakeholders from different regions? Analysis of an international Delphi survey to develop a core outcome set in gastric cancer surgery., PlOs One, 2021
Sheill G., Guinan E., O'Neill L., Normand C., Doyle SL., Moore S., Newell J., McDermott G., Ryan R., Reynolds JV., Hussey J., Preoperative exercise to improve fitness in patients undergoing complex surgery for cancer of the lung or oesophagus (PREHIIT): protocol for a randomized controlled trial, BMC Cancer, 2020
Sheill G., Reynolds S., O'Neill L., Mockler D., Reynolds JV., Hussey J., Guinan E.,, Cardiopulmonary Exercise Testing in Oesophagogastric Surgery: a Systematic Review, Cardiopulmonary Exercise Testing in Oesophagogastric Surgery: a Systematic Review, 2020, p12
O'Neill L., Reynolds S., Sheill G., Guinan E., Mockler D., Geoghegan J., Conlon K., Reynolds, J.V., Hussey J., Physical function in patients with resectable cancer of the pancreas and liver-a systematic review, Journal of Cancer Survivorship, 2020
O'NEILL L., GUINAN E., DOYLE S., CONNOLLY D., O'SULLIVAN J., BENNETT A., SHEILL G., SEGURADO R., KNAPP P., FAIRMAN C., NORMAND C., GEOGHEGAN J., CONLON K., REYNOLDS JV., HUSSEY J., Rehabilitation strategies following oesophagogastric and hepatopancreaticobiliary cancer (ReStOre II): a protocol for a randomised controlled trial, BMC Cancer, 20, 2020, p1 - 20
O'Neill L., Guinan E., Doyle S., O'Connor L., Sheill G., Smyth E., Fairman C., Segurado R., Connolly D., O'Sullivan J., Reynolds JV., Hussey J, ReStOre@Home: Feasibility study of a virtually delivered 12-week multidisciplinary rehabilitation programme for survivors of upper gastrointestinal (UGI) cancer - study protocol, HRB Open Research, 2020
Guinan, E.M., Bennett, A.E., Doyle, S.L., O'Neill, L, Gannon, J., Foley, G., Elliott, J.A., O'Sullivan, J., Reynolds, J.V., & Hussey, J., Measuring the impact of oesophagectomy on physical functioning and physical activity participation: a prospective study, BMC Cancer, 19, (682), 2019
O'Neill L., Knapp P., Doyle SL., Guinan E., Parker A.,Segurado R., Connolly D., O'Sullivan J., Reynolds JV., Hussey J, 'Patient and family co-developed participant information to improve recruitment rates, retention, and patient understanding in the Rehabilitation Strategies Following Oesophago-gastric and Hepatopancreaticobiliary Cancer (ReStOre II) trial: Protocol for a study within a trial (SWAT) [version 1; peer review: awaiting peer review]', 2019, -
O'Neill, L.M., Bennett, A.E., Guinan, E., Reynolds, J.V., Hussey, J., Physical recovery in the first six months following oesophago-gastric cancer surgery. Identifying rehabilitative needs: a qualitative interview study, Disability and Rehabilitation, 2019, p1-8
O'Neill, L. and Moran, J. and Guinan, E.M. and Reynolds, J.V. and Hussey, J., Physical decline and its implications in the management of oesophageal and gastric cancer: a systematic review, Journal of Cancer Survivorship, 12, (4), 2018, p601 - 618
Guinan EM, Forde C, O'Neill L, Gannon J, Doyle SL, Valkenet K, Trappenburg JCA, van Hillegersberg R, Ravi N, Hussey JM, Reynolds JV., Effect of preoperative inspiratory muscle training on physical functioning following esophagectomy., Diseases of the Esphagus, 32, (32), 2018, pdoy091-
Bennett, A.E., O'Neill, L., Connolly, D., Guinan, E.M., Boland, L., Doyle, S.L., O'Sullivan, J., Reynolds, J.V., & Hussey, J., Patient experiences of a physiotherapy-led multidisciplinary rehabilitative intervention after successful treatment for oesophago-gastric cancer, Supportive Care in Cancer, 26, (8), 2018, p2615 - 2623
Sheill G, Guinan E, O Neill L., Hevey D., Hussey J. , Physical Activity and Advanced Cancer: The views of Oncology and Palliative Care Physicians in Ireland. , Irish Journal of Medical Science, 187, (2), 2018, p337 - 343
O'Neill, L.M., Guinan, E., Doyle, S.L., Bennett, A.E., Murphy, C., Elliott, J.A., O'Sullivan, J., Reynolds, J.V., Hussey, J., The RESTORE Randomized Controlled Trial: Impact of a multidisciplinary rehabilitative program on cardiorespiratory fitness in esophagogastric cancer survivorship, Annals of Surgery, 268, (5), 2018, p747 - 755
Guinan, E.M., Doyle, S.L., Bennett, A.E., O'Neill, L, Gannon, J., Elliott, J.A., O'Sullivan, J., Reynolds, J.V., & Hussey, J., Sarcopenia during neoadjuvant therapy for oesophageal cancer: characterising the impact on muscle strength and physical performance, Supportive Care in Cancer, 26, (5), 2018, p1569 - 1576
Sheill. G., Guinan, E.M., O'Neill L, Hevey, D., Hussey, J. , Physical Activity and Advanced Cancer: The views of Chartered Physiotherapists in Ireland. , Physiotherapy Theory and Practice, 3, 2018, p1 - 8
O'Neill L, Gannon J, Guinan E, Reynolds JV, Hussey J. , Multidisciplinary rehabilitation across the esophageal cancer journey, Journal of Thoracic Diseases, 9, (12), 2017, pE1140 - E1142
Sheill G, Guinan E, Neill LO, Hevey D, Hussey J, The views of patients with metastatic prostate cancer towards physical activity: a qualitative exploration, Supportive Care in Cancer, 26, (6), 2017, p1747 - 1754
Linda O'Neill, Emer Guinan, Suzanne L Doyle, Jessie A. Elliott, Jacintha O'Sullivan, John V. Reynolds, Juliette Hussey, Rehabilitation Strategies following esophageal cancer (the ReStOre trial): a feasibility study, Diseases of the Esophagus, 30, (5), 2017, p1 - 8
Guinan, E.M., Doyle, S.L., O'Neill, L., Dunne, M.R., Foley, E.K., O'Sullivan, J., Reynolds, J.V., Hussey, J., Effects of a multimodal rehabilitation programme on inflammation and oxidative stress in oesophageal cancer survivors: the ReStOre feasibility study, Supportive Care in Cancer, 25, (3), 2016, p749 - 756