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Basil Elnazir
Clinical Associate Professor in Paediatr, Paediatrics

Biography

Prof Elnazir is a Consultant in Respiratory Paediatrics with strong academic background. He obtained his PhD from the university of Birmingham UK and completed his clinical training in the UK and Ireland. He has held many key leadership positions during his career with the Asthma Society of Ireland, Cystic Fibrosis Ireland, Make a wish Ireland and Internationally with Arab Pediatric Pulmonology association & as a coofounder of Middle East Cystic Fibrosis Association. He also served as a a National Specialty Director in Paediatrics at Royal College of Physicians of Ireland. He decided to expand his horizons by taking a 3 years sabbatical period and joined Al Jalila Children's specialty Hospital in Dubai in 2015 to set up a Paediatric Pulmonology Service. He was very quickly given the task of its Chief Medical Officer where he has steered progress to the fruitful opening of a 200 bed hospital. He had the opportunity to witness and actively help in shaping the development of Al Jalila Children's Hospital as the first standalone children's Hospital in the UAE and the Gulf region. This opportunity has given him a clear and in depth understanding of the healthcare model in the UAE and the Middle east region. He has published more than 60 manuscripts in peer-reviewed medical journals and presented extensively at national and international meetings. He has also served as an Editor and Reviewer to many Paediatric medical journals. He has a special clinical and research interest in asthma, cystic fibrosis, chronic cough and paediatric sleep medicine.

Publications and Further Research Outputs

Peer-Reviewed Publications

L Whilta, V Veitch, K O'Halloran, F O'Riordan, E Murphy, D Coghlan, B Elnazir, M Nadeem, Influenza in Children: Is there a link with Medical Complications or Inflammatory Markers?, Ir Med J, 2019 Journal Article, 2019

Kerley CP, Elnazir B, Greally P, Coghlan D. , Blunted serum 25(OH)D response to vitamin D3 supplementation in children with autism, Nutr Neurosci. , 2018 Journal Article, 2018 DOI

Hutchinson K, Kerley CP, Faul J, Greally P, Coghlan D, Louw M, Elnazir B, Rochev Y, Vitamin D receptor variants and uncontrolled asthma. , European annals of allergy and clinical immunology , 2017 Journal Article, 2017

Alokaily F, Saudi Medical Journal 2016. A year in a review., Saudi medical journal, 2017 Journal Article, 2017

Rauch D, Wetzke M, Reu S, Wesselak W, Schams A, Hengst M, Kammer B, Ley-Zaporozhan J, Kappler M, Proesmans M, Lange J, Escribano A, Kerem E, PTI (Persistent Tachypnea of Infancy) Study Group of the Kids Lung Register, Persistent Tachypnea of Infancy. Usual and Aberrant., American journal of respiratory and critical care medicine, 2016 Journal Article, 2016

Kerley Conor P, Kilbride Emma, Greally Peter, Elnazir Basil, Dietary Nitrate Acutely and Markedly Increased Exhaled Nitric Oxide in a Cystic Fibrosis Case , Clinical medicine & research , 14 , (3-4 ), 2016, p151 - 155 Journal Article, 2016

Kerley CP, Hutchinson K, Cormican L, Faul J, Greally P, Coghlan D, Elnazir B, Vitamin D3 for uncontrolled childhood asthma: a pilot study, Pediatric Allergy and Immunology 27 (4), 404-412 , 2016 Journal Article, 2016 DOI

Sheridan-Pereira, M., Murphy, J., Sloan, J., Crispino, G., Leahy, A., Corcoran, J.D., Dempsey, E., Elnazir, B., Gavin, P., Sharif, F., Gul, R., Satas, S., Murphy, J., Gormally, S., Shanaa, I., Waldron, D., Mc Mahon, P., Carson, J., Blanken, M., Bont, L., Paes, B., Respiratory syncytial virus preterm (32-36 Completed Weeks of Gestation) risk estimation measure for RSV hospitalization in Ireland, Pediatric Infectious Disease Journal, 35, (1), 2016, p19-24 Journal Article, 2016

Alokaily F, Saudi Medical Journal reforms 2015., Saudi Medical Journal, 2016 Journal Article, 2016

Fitzgerald C, George S, Linnane B, Chroinin M Ni, Mullane D, Herzig M, Greally P, Elnazir B, Healy F, McNally P, Irish Comparative Outcome Study (ICOS): a comparison of early childhood growth trajectories in children clinically diagnosed with cystic fibrosis with those diagnosed through newborn bloodspot screening , Journal of Cystic Fibrosis , (15 , 2016, pS98), 2016 Journal Article, 2016

Walsh Aisling, Phelan Fiona, Phelan Michelle, Ryan Mairead, Healy Fiona, Slattery DM, Elnazir Basil, Greally P, Linnane B, Chróinín Muireann Ní, Diagnosis and Treatment of Sleep Related Breathing Disorders in Children: 2007 to 2011 , Irish medical journal , 108 , (3 ), 2015, p71 - 73 Journal Article, 2015

Kerley, C.P., Elnazir, B., Faul, J., Cormican, L., Vitamin D as an adjunctive therapy in asthma. Part 1: A review of potential mechanisms, Pulmonary Pharmacology and Therapeutics, 32, 2015, p60-74 Journal Article, 2015

Casey, J.P., Goggin, P., McDaid, J., White, M., Ennis, S., Betts, D.R., Lucas, J.S., Elnazir, B., Lynch, S.A., A case report of primary ciliary dyskinesia, laterality defects and developmental delay caused by the co-existence of a single gene and chromosome disorder, BMC Medical Genetics, 16, (1), 2015 Journal Article, 2015

Kerley, C.P., Elnazir, B., Faul, J., Cormican, L., Vitamin D as an adjunctive therapy in asthma. Part 2: A review of human studies, Pulmonary Pharmacology and Therapeutics, 32, 2015, p75-92 Journal Article, 2015

Dunne K, Prior AR, Murphy K, Wall N, Leen G, Rogers TR, Elnazir B, Greally P, Renwick J, Murphy P, Emergence of persistent Aspergillus terreus colonisation in a child with cystic fibrosis., Medical mycology case reports, 9, 2015, p26-30 Journal Article, 2015 TARA - Full Text

Yousif TI, Elnazir B, Approach to a child with recurrent pneumonia., Sudanese Journal of Paediatrics, 2015 Journal Article, 2015

Fitzgerald C, Linnane B, Chroinin M Ni, Mullane D, Herzig M, Greally P, Elnazir B, Slattery D, Healy F, Mc Nally P, A comparison of z-scores for height and weight at 6 months in children clinically diagnosed with Cystic Fibrosis and children diagnosed through newborn bloodspot screening , (S546), 2015 Journal Article, 2015

Breen C, Finn D, Greally P, O'Connell G, Elnazir B, A National Paediatric Survey of Infection Control Measures in Cystic Fibrosis , 2015, 184 , SPRINGER LONDON LTD 236 GRAYS INN RD, 6TH FLOOR, LONDON WC1X 8HL, ENGLAND , 2015, pp278 - 279 Conference Paper, 2015

Shanahan D, Reviewer acknowledgement 2013., Journal of medical case reports, 2014 Journal Article, 2014

Renwick J, McNally P, John B, DeSantis T, Linnane B, Murphy P, The microbial community of the cystic fibrosis airway is disrupted in early life., PloS one, 9, (12), 2014, pe109798 Journal Article, 2014 TARA - Full Text DOI

Roddy MF, Greally P, Leen G, Kilbride E, Elnazir B, The Significance Of Indeterminant Ogtt In Children With Cystic Fibrosis , Pediatric Pulmonology , 49 , 2014, p413 - Journal Article, 2014

Nadeem M, Carter M, Di Fonzo D, Elnazir B, Recording abbreviation in clinical case note: are we good at it? , Irish medical journal , 107 , (6 ), 2014, p187 - 188 Journal Article, 2014 URL

Kandamany Nandini, Elnazir Basil, Greally Peter, Increased vigilance needed for the detection of thrombotic complications of central venous access in adolescent cystic fibrosis patients , Frontiers in pediatrics , 2 , 2014, p117 - Journal Article, 2014

Roddy MF, Greally P, Elnazir B, Iron Assessment In Children With Cystic Fibrosis , Pediatric Pulmonology , 48 , 2013, p412 - Journal Article, 2013

O'Connor, G., Tariq, M., Greally, P., Elnazir, B., The changing epidemiology of the bronchiolitis epidemic in Tallaght Hospital., Irish medical journal, 106, (10), 2013, p314-315 Journal Article, 2013

Marie Roddy, Basil Elnazir, Ciara McDonnell, M Nadeem, Peter Greally, The bone mineral density of children with CF , Bone abstracts , 6th International Conference on Children's Bone Health, 2013, pp177- Meeting Abstract, 2013

Roddy MF, Elnazir B, Greally P, The effect of PPI usage on bone health in children with cystic fibrosis (CF) , Journal of Cystic Fibrosis , 2012, ppS29- Conference Paper, 2012

Roddy MF, Elnazir B, Greally P, , Liver function and vitamin D in children with cystic fibrosis , Journal of Cystic Fibrosis , 2012, pppS120- Conference Paper, 2012

Gadelsayed Montasser Nadeem, Greally Peter, Elnazir Basil, Methicillin-resistant Staphylococcus aureus (Panton-Valentine leucocidin) cavitating pneumonia in a healthy child , Archives of Disease in Childhood , 2012 Journal Article, 2012

Assael BM, Pressler T, Bilton D et al,, Inhaled aztreonam lysine vs inhaled tobra mycin in cystic fibrosis : a comparative trial, J Cyst Fibros, 12, (2), 2012, p130 - 140 Journal Article, 2012 DOI

Nadeem Montasser, Elnazir Basil, Greally Peter, Congenital pulmonary malformation in children , Scientifica , 2012 , 2012, p209896 - Journal Article, 2012 DOI URL

Kandamany N, Tariq M, Elnazir B, Greally P, A case series of thrombotic and thromboembolic complications of central venous access in cystic fibrosis patients , Journal of Cystic Fibrosis, 2012, pppS149 - Conference Paper, 2012

Elnazir Basil, Oni Oluwole, Hassan Taha, Greally Peter, Paes Bosco, Does prophylaxis with palivizumab reduce hospitalisation rates for respiratory†syncytial†virus†related infection in cystic fibrosis children less than 2 years of age? , Journal of paediatrics and child health , 48 , (11 ), 2012, p1033 - 1038 Journal Article, 2012

Kilbride Emma, Widger John, Hussey Juliette, El Nazir Basil, Greally Peter, Exercise capacity in prepubertal children with cystic fibrosis , ISRN Pulmonology , 2012 , 2012 Journal Article, 2012

Roddy MF, Greally P, Elnazir B, The Effect Of High Dose Vitamin D Supplementation On Vitamin D Levels In Children With Cystic Fibrosis (cf) , Pediatric Pulmonology , 47 , 2012, p414 - Journal Article, 2012

Malikiwi, A., Elnazir, B., Asthma &swimming: What's the verdict?, Irish Medical Journal, 105, (6), 2012 Journal Article, 2012

Millar R, Clarke D, Greally P, ElNazir B, Linnane B, McNally P, The Study of Host Immunity and Early Lung Disease in Cystic Fibrosis (SHIELD CF), A Multicentre Longitudinal Paediatric CF Research Project in Ireland , 2012, 181 , SPRINGER LONDON LTD 236 GRAYS INN RD, 6TH FLOOR, LONDON WC1X 8HL, ENGLAND , 2012, ppS421 - S422 Conference Paper, 2012

Renwick J, McNally P, Linnane B, Greally P, Elnazir B, Lynch S, Murphy PG, The airway microbiome in children with cystic fibrosis , Journal of Cystic Fibrosis , 2012, pppS46- Conference Paper, 2012

Kandamany N, Tariq M, Elnazir B, Greally P, A case series of thrombotic and thromboembolic complications of central venous access in cystic fibrosis patients , Journal of Cystic Fibrosis, 2012, pppS149 - Conference Paper, 2012

Mujtaba G, Greally P, Elnazir B, Ursodeoxycholic Acid for Cystic Fibrosis Related Liver Disease, Our Experience , Pediatric Research , 70 , (S5 ), 2011, p534 - Journal Article, 2011

Muhammad T, Molony B, Kandamany N, Greally P, Elnazir B, Ten Years Audit Of Post Infectious Bronchiolitis Obliterans In Paediatrics Respiratory Centre , Acta Paediatrica , 100 , 2011, p82 - Journal Article, 2011

Roddy Marie Frances, Greally Peter, Clancy Geraldine, Leen Gerardine, Feehan Sinead, Elnazir Basil, Night blindness in a teenager with cystic fibrosis , Nutrition in Clinical Practice , 26 , (6 ), 2011, p718 - 721 Journal Article, 2011

McNally P, Coughlan C, Bergsson G, Doyle M, Taggart C, Adorini L, Uskokovic MR, El-Nazir B, Murphy P, Greally P, Greene CM, McElvaney NG, Vitamin D receptor agonists inhibit pro-inflammatory cytokine production from the respiratory epithelium in cystic fibrosis., Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 10, (6), 2011, p428-34 Journal Article, 2011

Nadeem M, Roddy M, O'Reilly R, Fitzpatrick P, Clancy G, Leen G, Elnazir B, Greally P, The impact on clinical progress of MRSA infection in the airways of children with cystic fibrosis , 2010, 179 , SPRINGER LONDON LTD 236 GRAYS INN RD, 6TH FLOOR, LONDON WC1X 8HL, ENGLAND , 2010, ppS499 - S499 Conference Paper, 2010

Zaid Ahmed Abou, Elnazir Basil, Greally P, A decade of non-cystic fibrosis bronchiectasis 1996-2006. , Irish medical journal , 2010 Journal Article, 2010

McNally Paul, Ervine E, Shields MD, Dimitrov Borislav D, El Nazir B, Taggart Clifford C, Greene Catherine M, McElvaney Noel G, Greally P, High concentrations of pepsin in bronchoalveolar lavage fluid from children with cystic fibrosis are associated with high interleukin-8 concentrations , Thorax , 2010, pthx - 2009 Journal Article, 2010

White M, Vaish S, Leen G, Clancy G, Greally P, Elnazir B, AUDIT OF MRSA PREVALENCE AND ERADICATION IN CYSTIC FIBROSIS , 2010, 179 , SPRINGER LONDON LTD 236 GRAYS INN RD, 6TH FLOOR, LONDON WC1X 8HL, ENGLAND , 2010, ppS227 - S228 Conference Paper, 2010

Glackin L, Leen G, Elnazir B, Greally P, Voriconazole in the treatment of allergic bronchopulmonary aspergillosis in cystic fibrosis, Irish medical journal , , (102 , (1 ), 2009, p2), 2009 Conference Paper, 2009

Roddy MF, Clancy G, Leen G, Elnazir B, Greally P, Diagnosis Of Pancreatic Function In Children With Cystic Fibrosis , Pediatric Pulmonology , 44 , 2009, p406 - Journal Article, 2009

Widger, J., Elnazir, B., Survey of the management of acute asthma in children, Irish Medical Journal, 102, (10), 2009 Journal Article, 2009

O'Reilly R, Fitzpatrick P, Leen G, Elnazir B, Greally P, Severe bone demineralisation is associated with higher mortality in children with cystic fibrosis. , Irish medical journal , 102 , (2 ), 2009, p47 - 49 Journal Article, 2009

Glackin L, Leen G, Elnazir B, Greally P, Voriconazole in the treatment of allergic bronchopulmonary aspergillosis in cystic fibrosis. , Irish medical journal , 102 , (1 ), 2009, p29 - 29 Journal Article, 2009

Zinc Status In Children With Cystic Fibrosis , Roddy MF, Elnazir B, Greally P, Pediatric Pulmonology, 44 p405 - 40, 2009 Conference Paper, 2009

Roddy MF, Elnazir B, Greally P, The effect of vitamin D supplementation on vitamin D level in children with cystic fibrosis (CF) , Journal of Cystic Fibrosis , 7 , 2008, pS92 - Journal Article, 2008

O'reilly R, Fitzpatrick P, Leen G, Elnazir B, Greally P, Severe Bone Demineralization Is Associatedwith Higher Mortality In Irish Adolescentswith Cystic Fibrosis , Pediatric Pulmonology, (43 , 2008, p439 - 44), 2008 Journal Article, 2008

Bacharier, L.B., Boner, A., Carlsen, K.-H., Eigenmann, P.A., Frischer, T., Götz, M., Helms, P.J., Hunt, J., Liu, A., Papadopoulos, N., Platts-Mills, T., Pohunek, P., Simons, F.E.R., Valovirta, E., Wahn, U., Wildhaber, J., Baraldi, E., Berdel, D., Bodart, E., Boner, A., Ribiero, L.J.D.B., Breborowicz, A., Carlsen, K.C.L., Carlsen, K.-H., De Benedictis, F.M., De Blic, J., Desager, K., Eigenmann, P.A., Elnazir, B., Fiocchi, A., Frischer, T., Gerrits, P., Gerrritsen, J., Gotz, M., Greally, P., Helms, P.J., Kajosaari, M., Kalayci, O., Kurzard, R., Dos Santos, J.M.L., Malmstrom, K., Nevot, S., Garcia, A.N., Papadopoulos, N., Pelkonen, A., Pohunek, P., Riedel, F., Pinto, J.E.R., Seidenberg, J., Valovirta, E., Van Aalderen, W.M.C., Vaughan, D., Wahn, U., Wildhaber, J., Wolthers, O.D., Diagnosis and treatment of asthma in childhood: A PRACTALL consensus report, Allergy: European Journal of Allergy and Clinical Immunology, 63, (1), 2008, p5-34 Journal Article, 2008

McNally PG, Doyle M, Taggart C, O'neill S, Elnazir B, Greene C, Murphy P, Greally P, Mcelvaney NG, Protease Anti-protease Balance And Innate Defence Proteins Levels In The Lungs Of Children With Cystic Fibrosis: Relationship Top. Aeruginosa Colonisation Status , Pediatric Pulmonology , 42 , 2007, p262 - Pediatric Pulmonology , 42, p262 , 2007 Conference Paper, 2007

Govindaraj, P.R., Saladi, M., Elnazir, B., Self-assessment, Current Paediatrics, 15, (7), 2005, p599-604 Journal Article, 2005

Leen GB, Elnazir B, Greally P, Bone Mineral Density In An Irish Adolescent Population With Cystic Fibrosis , Pediatric Pulmonology , 40 , 2005, p357 - Journal Article, 2005

Elnazir, B., Marshall, J.M., Kumar, P., Postnatal development of the pattern of respiratory and cardiovascular response to systemic hypoxia in the piglet: The roles of adenosine, Journal of Physiology, 492, (2), 1996, p573-585 Journal Article, 1996

Thomas, T., Elnazir, B., Marshall, J., Differentiation of the peripherally mediated from the centrally mediated influences of adenosine in the rat during systemic hypoxia, Experimental Physiology, 79, (5), 1994, p809-822 Journal Article, 1994

Elnazir, B.K., Marshall, J.M., Further experiments on the role of adenosine in the vasodilatation induced by systematic hypoxia in skeletal muscle of the anaesthetized rat, Journal of Physiology, 467, 1993 Journal Article, 1993

Elnazir, B.K., Pepper, D.R., Kumar, P., The effect of chronic hypoxia from birth upon the initial ventilatory responses to CO2 and O2 in conscious, newborn rats, Journal of Physiology, 467, 1993 Journal Article, 1993

Elnazir, B.K., Kumar, P., Marshall, J.M., Modulation by theophylline of the ventilatory response to moderate hypoxia in conscious, newborn rats, Journal of Physiology, 446, 1992 Journal Article, 1992

Kumar P, Thomas T, Elnazir BK, The reflex ventilatory responses of conscious, newborn rats to alternations of inspiratory oxygen concentration., Journal of developmental physiology, 1992 Journal Article, 1992

Kumar P, Thomas T, Elnazir BK, The reflex ventilatory responses of conscious, newborn rats to alternations of inspiratory oxygen concentration., Journal of developmental physiology, 1992 Journal Article, 1992

Elnazir, B.K., Kumar, P., Marshall, J.M., Modulation by theophylline of the ventilatory response to moderate hypoxia in conscious, newborn rats, Journal of Physiology, 446, 1992 Journal Article, 1992

Thomas, T., Elnazir, B.K., Kumar, P., The ventilatory response to alternations of FiO2in conscious, newborn rats, Journal of Physiology, 435, 1991 Journal Article, 1991

Non-Peer-Reviewed Publications

Montasser Nadeem, Basil Elnazir, An update in children under five', Medical independent,, 2013 Journal Article, 2013

Nadeem Montaser, Colhoun Eric, Elnazir Basil, Mediastinal foregut malformation in a child with recurring cough , Medical Independent, 2012 Review, 2012

Research Expertise

Description

1-Focus on the role of Vitamin D and asthma control in children. 2-longitudinally examining the factors which influence early lung disease in cystic fibrosis. 3-Polymicrobial Communities in The Lower Airways of Children With Cystic Fibrosis: Development, Diversity and Consequences on Lung Inflammation I am currently focussing on attempting to delineate longitudinal Polymicrobial diversity in the CF airways. This is critically opportune as New born screening commenced in Ireland in 2011 where it is now possible to revaluate the need of standard practices such as prophylaxis antibiotics in newly diagnosed children with CF up to the age of 3 years. I am also internationally collaborating with researchers in the Middle East regarding the genetics of CF specially in the Arab population

Projects

  • Title
    • A double-blind, placebo- controlled trial of vitamin D3 for paediatric asthma
  • Funding Agency
    • National Children's Hospital Foundation
  • Date From
    • 2013
  • Date To
    • 2014
  • Title
    • Randomized, double-blind, placebo controlled trial of dietary nitrate in paediatric cystic fibrosis.
  • Funding Agency
    • National Children's Hospital Foundation
  • Date From
    • 2015
  • Date To
    • 2015
  • Title
    • Post hoc biochemical analysis of samples from a vitamin D RCT in childhood asthmatics.
  • Funding Agency
    • National Children's Hospital Foundation
  • Date From
    • 2015
  • Date To
    • 2016
  • Title
    • randomised, double-blind, placebo-controlled, multi-national, Phase III trial to assess the efficacy and safety of 300 IR sublingual immunotherapy (SLIT) administered as allergen-based tablets once daily to adolescents and children above the age of 5 years, suffering from house dust mite allergic rhinitis
  • Funding Agency
    • Pharmaceutical company
  • Date From
    • 2009
  • Date To
    • 2010
  • Title
    • . Phase III Study to Evaluate Clinical Efficacy and Safety of Avian Polyclonal Anti-Pseudomonas Antibodies (IgY) in Prevention of Recurrence of Pseudomonas Aeruginosa Infection in Cystic Fibrosis Patients.
  • Funding Agency
    • European CF
  • Date From
    • 2013
  • Date To
    • 2015

Keywords

CHILDHOOD ASTHMA; Cystic Fibrosis; Paediatric sleep disordered breathing ; Primary Ciliary Dyskinesia

Recognition

Representations

National Speciality Director In Paediatrics RCPI (In charge of Paediatrics Higher Specialist Registrar training in Ireland). 2011

Medical Advisor to Make a Wish Ireland (Charitable organisation). 2011

Chairperson of the medical committee of the Asthma Society of Ireland 2011

MECFA (Middle East Cystic Fibrosis Association). 2015

Arab Paediatric Pulmonology Association (APPA). 2011

Memberships

Member of the British Physiological Society. 1997

Member of the European Respiratory Society 2004

Member of the American Thoracic Society 2004