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Dr. Anne Molloy
Fellow Emeritus, Clinical Medicine
Fellow Emeritus, Biochemistry

Publications and Further Research Outputs

Peer-Reviewed Publications

Moore K, Hughes CF, Hoey L, Ward M, Cunningham C, Molloy AM, Strain JJ, McCarroll K, Casey MC, Tracey F, Laird E, O'Kane M, McNulty H., B-vitamins in Relation to Depression in Older Adults Over 60 Years of Age: The Trinity Ulster Department of Agriculture (TUDA) Cohort Study., Journal of the American Medical Directors Association, 2019, p551-557.e1 Journal Article, 2019 DOI

Cawley S, O'Malley EG, Kennedy RAK, Reynolds CME, Molloy AM, Turner MJ., The relationship between maternal plasma homocysteine in early pregnancy and birth weight., J Matern Fetal Neonatal Med, 2019, p1-5 Journal Article, 2019 DOI

Laird EJ, O'Halloran AM, Carey D, O'Connor D, Kenny RA, Molloy AM, Voluntary fortification is ineffective to maintain the vitamin B12 and folate status of older Irish adults: evidence from the Irish Longitudinal Study on Ageing (TILDA)., The British journal of nutrition, 2018, p111 - 120 Journal Article, 2018 TARA - Full Text

Shane B, Pangilinan F, Mills JL, Fan R, Gong T, Cropp CD, Kim Y, Ueland PM, Bailey-Wilson JE, Wilson AF, Brody LC, Molloy AM., The 677C"T variant of MTHFR is the major genetic modifier of biomarkers of folate status in a young, healthy Irish population., The American journal of clinical nutrition, 108, (6), 2018, p1334-1341 Journal Article, 2018 DOI

Höller, U. and Bakker, S.J.L. and DÌsterloh, A. and Frei, B. and Köhrle, J. and Konz, T. and Lietz, G. and McCann, A. and Michels, A.J. and Molloy, A.M. and Murakami, H. and Rein, D. and Saris, W.H.M. and Schmidt, K. and Shimbo, K. and Schumacher, S. and Vermeer, C. and Kaput, J. and Weber, P. and Eggersdorfer, M. and Rezzi, S., Micronutrient status assessment in humans: Current methods of analysis and future trends, TrAC - Trends in Analytical Chemistry, 102, 2018, p110-122 Journal Article, 2018 DOI

O'Malley EG, Cawley S, Kennedy RAK, Reynolds CME, Molloy A, Turner MJ., Maternal anaemia and folate intake in early pregnancy., Journal of public health (Oxford, England), 2018, pdy013- Journal Article, 2018 DOI

Laird, E. and O'Halloran, A.M. and Carey, D. and Healy, M. and O'Connor, D. and Moore, P. and Shannon, T. and Molloy, A.M. and Kenny, R.A., The Prevalence of Vitamin D Deficiency and the Determinants of 25(OH)D Concentration in Older Irish Adults: Data from the Irish Longitudinal Study on Ageing (TILDA), Journals of Gerontology - Series A Biological Sciences and Medical Sciences, 73, (4), 2018, p519-525 Journal Article, 2018 DOI

Molloy AM., Should vitamin B12 status be considered in assessing risk of neural tube defects?, Annals of the New York Academy of Sciences, 2018, p109-125 Journal Article, 2018 DOI

Molloy AM, Mills JL., Fortifying food with folic acid to prevent neural tube defects: are we now where we ought to be?, The American journal of clinical nutrition, 107, (6), 2018, p857-858 Journal Article, 2018 DOI

Brosnan, J.T. and Mills, J.L. and Ueland, P.M. and Shane, B. and Fan, R. and Chiu, C.-Y. and Pangilinan, F. and Brody, L.C. and Brosnan, M.E. and Pongnopparat, T. and Molloy, A.M., Lifestyle, metabolite, and genetic determinants of formate concentrations in a cross-sectional study in young, healthy adults, American Journal of Clinical Nutrition, 107, (3), 2018, p345-354 Journal Article, 2018 DOI

McCann A, McNulty H, Rigby J, Hughes CF, Hoey L, Molloy AM, Cunningham CJ, Casey MC, Tracey F, O'Kane MJ, McCarroll K, Ward M, Moore K, Strain JJ, Moore A., Effect of Area-Level Socioeconomic Deprivation on Risk of Cognitive Dysfunction in Older Adults., Journal of the American Geriatrics Society, 2018, p1 - 7 Journal Article, 2018 DOI

International League Against Epilepsy Consortium on Complex Epilepsies., Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies., Nature communications, 9, (1), 2018, p5269 Journal Article, 2018 DOI TARA - Full Text

O'Reilly J, Pangilinan F, Hokamp K, Ueland PM, Brosnan JT, Brosnan ME, Brody LC, Molloy AM., The impact of common genetic variants in the mitochondrial glycine cleavage system on relevant metabolites., Molecular genetics and metabolism reports, 16, 2018, p20-22 Journal Article, 2018 DOI

Mills JL, Molloy AM, Reynolds EH., Do the benefits of folic acid fortification outweigh the risk of masking vitamin B12 deficiency?, BMJ (Clinical research ed.), 360, 2018, pk724 Review, 2018 DOI

Bernard DJ, Pangilinan FJ, Cheng J, Molloy AM, Brody LC., Mice lacking the transcobalamin-vitamin B12 receptor, CD320, suffer from anemia and reproductive deficits when fed vitamin B12-deficient diet., Human molecular genetics, 27, (20), 2018, p3627-3640 Journal Article, 2018 DOI

Ntlholang O, McCarroll K, Laird E, Molloy AM, Ward M, McNulty H, Hoey L, Hughes CF, Strain JJ, Casey M, Cunningham C, The relationship between adiposity and cognitive function in a large community-dwelling population: data from the Trinity Ulster Department of Agriculture (TUDA) ageing cohort study., The British journal of nutrition, 2018 Journal Article, 2018

Mossey, P.A. and Little, J. and Steegers-Theunissen, R. and Molloy, A. and Peterlin, B. and Shaw, W.C. and Johnson, C. and FitzPatrickd, D.R. and Franceschelli, P. and Rubini, M., Genetic interactions in nonsyndromic orofacial clefts in Europe-EUROCRAN Study, Cleft Palate-Craniofacial Journal, 54, (6), 2017, p623-630 Journal Article, 2017 DOI

Velkova A, Diaz JEL, Pangilinan F, Molloy AM, Mills JL, Shane B, Sanchez E, Cunningham C, McNulty H, Cropp CD, Bailey-Wilson JE, Wilson AF, Brody LC., The FUT2 secretor variant p.Trp154Ter influences serum vitamin B12 concentration via holo-haptocorrin, but not holo-transcobalamin, and is associated with haptocorrin glycosylation., Human molecular genetics, 26, (24), 2017, p4975-4988 Journal Article, 2017 DOI

Murphy M.M, Fernandez-Ballart J.D, Molloy A.M, Canals J, Moderately elevated maternal homocysteine at preconception is inversely associated with cognitive performance in children 4months and 6years after birth., Maternal & Child Nutrition, 13, (12), 2017, pe12289- Journal Article, 2017 DOI URL

Cawley S, McCartney D, Woodside JV, Sweeney MR, McDonnell R, Molloy AM, Turner MJ., Optimization of folic acid supplementation in the prevention of neural tube defects., Journal of public health (Oxford, England), 2017, p1-8 Journal Article, 2017 DOI

Laird E, Molloy A.M, McNulty H, Ward M, McCarroll K, Hoey L, Hughes C.F, Cunningham C, Strain J.J, Casey M.C, Greater yogurt consumption is associated with increased bone mineral density and physical function in older adults, Osteoporosis International, 28, (8), 2017, p2409 - 2419 Journal Article, 2017 DOI URL

Green R, Allen L.H, BjÃ"rke-Monsen A.-L, Brito A, Guéant J.-L, Miller J.W, Molloy A.M, Nexo E, Stabler S, Toh B.-H, Ueland P.M, Yajnik C, Vitamin B12 deficiency, Nature Reviews Disease Primers, 3, 2017 Review, 2017 DOI URL

Neural Tube defects: Mechanisms of Folate in, editor(s)C.D. Karakochuk, K.C. Whitfield, T.J. Green and K. Kraemer , The Biology of the First 1000 Days, CRC Press, Taylor and Francis Group, 2017, pp123 - 136, [Molloy Annw M] Book Chapter, 2017 URL

Gilbert E, O'Reilly S, Merrigan M, McGettigan D, Molloy AM, Brody LC, Bodmer W, Hutnik K, Ennis S, Lawson DJ, Wilson JF, Cavalleri GL., The Irish DNA Atlas: Revealing Fine-Scale Population Structure and History within Ireland., Scientific reports, 7, (1), 2017, p17199 Journal Article, 2017 DOI

Laird E, O'Halloran AM, Carey D, Healy M, O'Connor D, Moore P, Shannon T, Molloy AM, Kenny RA., The prevalence of vitamin D deficiency and the determinants of 25(OH)D concentration in older Irish adults: Data from The Irish Longitudinal Study on Ageing (TILDA)., The journals of gerontology. Series A, Biological sciences and medical sciences, 2017 Journal Article, 2017 DOI

Molloy AM, Pangilinan F, Brody LC., Genetic Risk Factors for Folate-Responsive Neural Tube Defects., Annual review of nutrition, 37, 2017, p269-291 Review, 2017 DOI

Hughes C.F, Ward M, Tracey F, Hoey L, Molloy A.M, Pentieva K, McNulty H, B-vitamin intake and biomarker status in relation to cognitive decline in healthy older adults in a 4-year follow-up study, Nutrients, 9, (1), 2017, p53- Journal Article, 2017 TARA - Full Text DOI URL

O'Sullivan F, Laird E, Kelly D, van Geffen J, van Weele M, McNulty H, Hoey L, Healy M, McCarroll K, Cunningham C, Casey M, Ward M, Strain JJ, Molloy AM, Zgaga L., Ambient UVB Dose and Sun Enjoyment Are Important Predictors of Vitamin D Status in an Older Population., Journal of Nutrition, 147, (5), 2017, p858-868. Journal Article, 2017 DOI

O'Reilly S.L, McGlynn A.P, McNulty H, Reynolds J, Wasson G.R, Molloy A.M, Strain J.J, Weir D.G, Ward M, McKerr G, Scott J.M, Downes C.S, Folic acid supplementation in postpolypectomy patients in a randomized controlled trial increases tissue folate concentrations and reduces aberrant DNA biomarkers in colonic tissues adjacent to the former polyp site, Journal of Nutrition, 146, (5), 2016, p933 - 939 Journal Article, 2016 URL DOI

Vaish S, White M, Daly L, Molloy AM, Staines A, Sweeney MR, Synthetic folic acid intakes and status in children living in Ireland exposed to voluntary fortification., American Journal of Clinical Nutrition, 103, (2), 2016, p512-518 Journal Article, 2016 DOI

SobczyÅ"ska-Malefora A, Pangilinan F, Plant G.T, Velkova A, Harrington D.J, Molloy A.M, Brody L.C, Association of a transcobalamin II genetic variant with falsely low results for the holotranscobalamin immunoassay, European Journal of Clinical Investigation, 46, (5), 2016, p434 - 439 Journal Article, 2016 DOI URL

Bueno O, Molloy AM, Fernandez-Ballart JD, García-Minguillán CJ, Ceruelo S, Ríos L, Ueland PM, Meyer K, Murphy MM, Common Polymorphisms That Affect Folate Transport or Metabolism Modify the Effect of the MTHFR 677C > T Polymorphism on Folate Status., Journal of Nutrition, 146, (1), 2016, p1-8 Journal Article, 2016 DOI

E. Laird, M. C. Casey, M. Ward, L. Hoey, C. F. Hughes, K. Mccarroll, C. Cunningham, J. J. Strain, H. Mcnulty, A. M. Molloy, Dairy intakes in older Irish adults and effects on vitamin micronutrient status: Data from the TUDA study, The journal of nutrition, health & aging, 2016, p1-8 Journal Article, 2016 TARA - Full Text DOI

Deac OM, Mills JL, Gardiner CM, Shane B, Quinn L, Midttun O, McCann A, Meyer K, Ueland PM, Fan R, Lu Z, Brody LC, Molloy AM, Serum Immune System Biomarkers Neopterin and Interleukin-10 Are Strongly Related to Tryptophan Metabolism in Healthy Young Adults, J Nutr, 146, (9), 2016, p1801 - 1806 Journal Article, 2016 DOI

Catena A, Muñoz-Machicao JA, Torres-Espínola FJ, Martínez-Zaldívar C, Diaz-Piedra C, Gil A, Haile G, Györei E, Molloy AM, Decsi T, Koletzko B, Campoy C, Folate and long-chain polyunsaturated fatty acid supplementation during pregnancy has long-term effects on the attention system of 8.5-y-old offspring: a randomized controlled trial., American Journal of Clinical Nutrition, 103, (1), 2016, p115-127 Journal Article, 2016 DOI

Vandermeer J.E, Carter T.C, Pangilinan F, Mitchell A, Kurnat-Thoma E, Kirke P.N, Troendle J.F, Molloy A.M, Munger R.G, Feldkamp M.L, Mansilla M.A, Mills J.L, Murray J.C, Brody L.C, Evaluation of proton-coupled folate transporter (SLC46A1) polymorphisms as risk factors for neural tube defects and oral clefts, American Journal of Medical Genetics, Part A, 170, (4), 2016, p1007 - 1016 Journal Article, 2016 URL DOI

Pentieva K, Selhub J, Paul L, Molloy A.M, McNulty B, Ward M, Marshall B, Dornan J, Reilly R, Parle-McDermott A, Bradbury I, Ozaki M, Scott J.M, McNulty H, Evidence from a randomized trial that exposure to supplemental folic acid at recommended levels during pregnancy does not lead to increasedunmetabolized folicacid concentrations in maternal or cord blood, Journal of Nutrition, 146, (3), 2016, p494 - 500 Journal Article, 2016 URL DOI

Coen RF, McCarroll K, Casey M, McNulty H, Laird E, Molloy AM, Ward M, Strain JJ, Hoey L, Hughes C, Cunningham CJ, The Frontal Assessment Battery: Normative Performance in a Large Sample of Older Community-Dwelling Hospital Outpatient or General Practitioner Attenders., Journal of geriatric psychiatry and neurology, 29, (6), 2016, p338-343 Journal Article, 2016 TARA - Full Text DOI

Szymczak S, Holzinger E, Dasgupta A, Malley J.D, Molloy A.M, Mills J.L, Brody L.C, Stambolian D, Bailey-Wilson J.E, r2VIM: A new variable selection method for random forests in genome-wide association studies, BioData Mining, 9, (1), 2016, p7 Journal Article, 2016 TARA - Full Text URL DOI

Molloy A.M, Pangilinan F, Mills J.L, Shane B, O'Neill M.B, McGaughey D.M, Velkova A, Abaan H.O, Ueland P.M, McNulty H, Ward M, Strain J.J, Cunningham C, Casey M, Cropp C.D, Kim Y, Bailey-Wilson J.E, Wilson A.F, Brody L.C, A Common Polymorphism in HIBCH Influences Methylmalonic Acid Concentrations in Blood Independently of Cobalamin, American Journal of Human Genetics, 98, (5), 2016, p869 - 882 Journal Article, 2016 TARA - Full Text DOI URL

Ozel A.B, Mcgee B, Siemieniak D, Jacobi P.M, Haberichter S.L, Brody L.C, Mills J.L, Molloy A.M, Ginsburg D, Li J.Z, Desch K.C, Genome-wide studies of von Willebrand factor propeptide identify loci contributing to variation in propeptide levels and von Willebrand factor clearance, Journal of Thrombosis and Haemostasis, 14, (9), 2016, p1888-1898 Journal Article, 2016 URL DOI

Deac O.M, Mills J.L, Shane B, Midttun O, Ueland P.M, Brosnan J.T, Brosnan M.E, Laird E, Gibney E.R, Fan R, Wang Y, Brody L.C, Molloy A.M, Tryptophan catabolism and vitamin B-6 status are affected by gender and lifestyle factors in healthy young adults, Journal of Nutrition, 145, (4), 2015, p701 - 707 Journal Article, 2015 URL DOI

Clarke M, Ward M, Dickey W, Hoey L, Molloy A.M, Waldron L, Varghese A, McCann A, Blayney J.K, McNulty H, B-vitamin status in relation to bone mineral density in treated celiac disease patients, Scandinavian Journal of Gastroenterology, 50, (8), 2015, p975 - 984 Journal Article, 2015 URL DOI

Bailey L.B, Stover P.J, McNulty H, Fenech M.F, Gregory J.F, Mills J.L, Pfeiffer C.M, Fazili Z, Zhang M, Ueland P.M, Molloy A.M, Caudill M.A, Shane B, Berry R.J, Bailey R.L, Hausman D.B, Raghavan R, Raiten D.J, Biomarkers of nutrition for development-Folate review, Journal of Nutrition, 145, (7), 2015, p1636S - 1680S Journal Article, 2015 URL DOI

McCarroll K, Beirne A, Casey M, McNulty H, Ward M, Hoey L, Molloy A, Laird E, Healy M, Strain JJ, Cunningham C, Determinants of 25-hydroxyvitamin D in older Irish adults., Age and Ageing, 44, (5), 2015, p847-853 Journal Article, 2015 DOI TARA - Full Text

Hopkins S.M, Gibney M.J, Nugent A.P, McNulty H, Molloy A.M, Scott J.M, Flynn A, Strain J.J, Ward M, Walton J, McNulty B.A, Impact of voluntary fortification and supplement use on dietary intakes and biomarker status of folate and vitamin B-12 in Irish adults, American Journal of Clinical Nutrition, 101, (6), 2015, p1163 - 1172 Journal Article, 2015 URL DOI

Keaveney E.M, Price R.K, Hamill L.L, Wallace J.M.W, McNulty H, Ward M, Strain J.J, Ueland P.M, Molloy A.M, Piironen V, Von Reding W, Shewry P.R, Ward J.L, Welch R.W, Postprandial plasma betaine and other methyl donor-related responses after consumption of minimally processed wheat bran or wheat aleurone, or wheat aleurone incorporated into bread, British Journal of Nutrition, 113, (3), 2015, p445 - 453 Journal Article, 2015 URL DOI TARA - Full Text

, 18th Meeting of the Irish Society of Human Genetics, Friday 4th September 2015: Dublin City University., 2015 Journal Article, 2015

Carter T.C, Pangilinan F, Molloy A.M, Fan R, Wang Y, Shane B, Gibney E.R, Midttun Ø, Ueland P.M, Cropp C.D, Kim Y, Wilson A.F, Bailey-Wilson J.E, Brody L.C, Mills J.L, Common variants at putative regulatory sites of the tissue nonspecific alkaline phosphatase gene influence circulating pyridoxal 5'-phosphate concentration in healthy adults, Journal of Nutrition, 145, (7), 2015, p1386 - 1393 Journal Article, 2015 URL DOI

Ozaki M, Molloy AM, Mills JL, Fan R, Wang Y, Gibney ER, Shane B, Brody LC, Parle-McDermott A, The Dihydrofolate Reductase 19 bp Polymorphism Is Not Associated with Biomarkers of Folate Status in Healthy Young Adults, Irrespective of Folic Acid Intake., Journal of Nutrition, 145, (10), 2015, 2207-2211 Journal Article, 2015 DOI

Mills J.L, Fan R, Brody L.C, Liu A, Ueland P.M, Wang Y, Kirke P.N, Shane B, Molloy A.M, Maternal choline concentrations during pregnancy and choline-related genetic variants as risk factors for neural tube defects, American Journal of Clinical Nutrition, 100, (4), 2014, p1069 - 1074 Journal Article, 2014 TARA - Full Text URL DOI

Ludwig KU, Böhmer AC, Rubini M, Mossey PA, Herms S, Nowak S, Reutter H, Alblas MA, Lippke B, Barth S, Paredes-Zenteno M, Muñoz-Jimenez SG, Ortiz-Lopez R, Kreusch T, Hemprich A, Martini M, Braumann B, Jäger A, Pötzsch B, Molloy A, Peterlin B, Hoffmann P, Nöthen MM, Rojas-Martinez A, Knapp M, Steegers-Theunissen RP, Mangold E., Strong association of variants around FOXE1 and orofacial clefting., Journal of Dental Research, 93, (4), 2014, p376 - 378 Journal Article, 2014 DOI

Nzila A, Okombo J, Molloy AM, Impact of folate supplementation on the efficacy of sulfadoxine/pyrimethamine in preventing malaria in pregnancy: the potential of 5-methyl-tetrahydrofolate., Journal of Antimicrobial Chemotherapy, 69, (2), 2014, p323 - 330 Journal Article, 2014 DOI TARA - Full Text

Devalia V, Hamilton MS, Molloy AM;the British Committee for Standards in Haematology, Guidelines for the diagnosis and treatment of cobalamin and folate disorders., British Journal of Haematology, 166, (4), 2014, p496-513 Journal Article, 2014 DOI

Ma Q, Ozel A.B, Ramdas S, McGee B, Khoriaty R, Siemieniak D, Li H.-D, Guan Y, Brody L.C, Mills J.L, Molloy A.M, Ginsburg D, Li J.Z, Desch K.C, Genetic variants in PLG, LPA, and SIGLEC 14 as well as smoking contribute to plasma plasminogen levels, Blood, 124, (20), 2014, p3155 - 3164 Journal Article, 2014 DOI URL

Crider, KS, Devine, O, Hao, L, Dowling, NF, Li, S, Molloy, AM, Li, Z, Zhu, JH, Berry, RJ, Population red blood cell folate concentrations for prevention of neural tube defects: bayesian model, BMJ-BRITISH MEDICAL JOURNAL, 349, 2014, pg4554- Journal Article, 2014 TARA - Full Text DOI

Laird E, McNulty H, Ward M, Hoey L, McSorley E, Wallace JM, Carson E, Molloy AM, Healy M, Casey MC, Cunningham C, Strain JJ., Vitamin D deficiency is associated with inflammation in older irish adults., Journal of Clinical and Endocrinology Metabolism, 99, (5), 2014, p1807 - 1815 Journal Article, 2014 DOI

Pangilinan F, Molloy AM, Mills JL, Troendle JF, Parle-McDermott A, Kay DM,Browne ML, McGrath EC, Abaan H, Sutton M, Kirke PN, Caggana M, Shane B, Scott JM, Brody LC. , Replication and exploratory analysis of 24 candidate risk polymorphisms for neural tube defects., BMC Medical Genetics , 15, (1), 2014, p102- Journal Article, 2014 TARA - Full Text DOI

García-Minguillán C.J, Fernandez-Ballart J.D, Ceruelo S, Ríos L, Bueno O, Berrocal-Zaragoza M.I, Molloy A.M, Ueland P.M, Meyer K, Murphy M.M, Riboflavin status modifies the effects of methylenetetrahydrofolate reductase (MTHFR) and methionine synthase reductase (MTRR) polymorphisms on homocysteine, Genes and Nutrition, 9, (6), 2014, p435- Journal Article, 2014 TARA - Full Text URL DOI

Molloy AM, Einri CN, Jain D, Laird E, Fan R, Wang Y, Scott JM, Shane B, Brody LC, Kirke PN, Mills JL.., Is low iron status a risk factor for neural tube defects?, Birth Defects Research A Clinical and Molecular Teratology., 100, (2), 2014, p100 - 106 Journal Article, 2014 TARA - Full Text

McGlynn AP, Wasson GR, O'Reilly SL, McNulty H, Downes CS, Chang CK, Hoey L, Molloy AM, Ward M, Strain JJ, McKerr G, Weir DG, Scott JM, Low colonocyte folate is associated with uracil misincorporation and global DNA hypomethylation in human colorectum., The Journal of nutrition, 143, (1), 2013, p27-33 Journal Article, 2013 DOI TARA - Full Text

McNulty B, McNulty H, Marshall B, Ward M, Molloy AM, Scott JM, Dornan J, Pentieva K., Impact of continuing folic acid after the first trimester of pregnancy: findings of a randomized trial of Folic Acid Supplementation in the Second and Third Trimesters., American Journal of Clinical Nutrition , 98, (1), 2013, p92 - 98 Journal Article, 2013 TARA - Full Text

Böhmer AC, Mangold E, Tessmann P, Mossey PA, Steegers-Theunissen RP, Lindemans J, Bouwman-Both M, Rubini M, Franceschelli P, Aiello V, Peterlin B, Molloy AM, Nöthen MM, Knapp M, Ludwig KU., Analysis of susceptibility loci for nonsyndromic orofacial clefting in a European trio sample., American Journal of Medical Genetics, 161, (10), 2013, p2545 - 2549 Journal Article, 2013

Desch KC, Ozel AB, Siemieniak D, Kalish Y, Shavit JA, Thornburg CD, Sharathkumar AA, McHugh CP, Laurie CC, Crenshaw A, Mirel DB, Kim Y, Cropp CD, Molloy AM, Kirke PN, Bailey-Wilson JE, Wilson AF, Mills JL, Scott JM, Brody LC, Li JZ, Ginsburg D, Linkage analysis identifies a locus for plasma von Willebrand factor undetected by genome-wide association., Proceedings of the National Academy of Sciences of the United States of America, 110, (2), 2013, p588-93 Journal Article, 2013 DOI TARA - Full Text

Pangilinan F, Molloy AM, Mills JL, Troendle JF, Parle-McDermott A, Signore C, O'Leary VB, Chines P, Seay JM, Geiler-Samerotte K, Mitchell A, VanderMeer JE, Krebs KM, Sanchez A, Cornman-Homonoff J, Stone N, Conley M, Kirke PN, Shane B, Scott JM, Brody LC, Evaluation of common genetic variants in 82 candidate genes as risk factors for neural tube defects., BMC medical genetics, 13, 2012, p62 Journal Article, 2012 DOI TARA - Full Text

Molloy AM, Genetic aspects of folate metabolism., Sub-cellular biochemistry, 56, 2012, p105-30 Journal Article, 2012

Wallace JM, McCormack JM, McNulty H, Walsh PM, Robson PJ, Bonham MP, Duffy ME, Ward M, Molloy AM, Scott JM, Ueland PM, Strain JJ, Choline supplementation and measures of choline and betaine status: a randomised, controlled trial in postmenopausal women., The British journal of nutrition, 108, (7), 2012, p1264-71 Journal Article, 2012

O'Luanaigh C, O'Connell H, Chin AV, Hamilton F, Coen R, Walsh C, Walsh JB, Coakley D, Molloy A, Scott J, Cunningham CJ, Lawlor BA, Loneliness and vascular biomarkers: the Dublin Healthy Ageing Study., International journal of geriatric psychiatry, 27, (1), 2012, p83-8 Journal Article, 2012 DOI

Scott J, Valente E, Molloy A, Holotranscobalamin: Not Ready for Prime Time., Clinical chemistry, 2012 Journal Article, 2012

Lamarre SG, Molloy AM, Reinke SN, Sykes BD, Brosnan ME, Brosnan JT, Formate can differentiate between hyperhomocysteinemia due to impaired remethylation and impaired transsulfuration., American journal of physiology. Endocrinology and metabolism, 302, (1), 2012, pE61-7 Journal Article, 2012 DOI TARA - Full Text

Molloy AM, Kappen C, Papers from the 7th International Neural Tube Defects Conference., Birth defects research. Part A, Clinical and molecular teratology, 94, (10), 2012, p747-8 Journal Article, 2012

Scott JM, Molloy AM, The discovery of vitamin B(12)., Annals of nutrition & metabolism, 61, (3), 2012, p239-45 Journal Article, 2012

Minguzzi S, Molloy AM, Peadar K, Mills J, Scott JM, Troendle J, Pangilinan F, Brody L, Parle-McDermott A, Genotyping of a tri-allelic polymorphism by a novel melting curve assay in MTHFD1L: an association study of nonsyndromic Cleft in Ireland., BMC medical genetics, 13, 2012, p29 Journal Article, 2012 TARA - Full Text DOI

Robinson DJ, O'Luanaigh C, Tehee E, O'Connell H, Hamilton F, Chin AV, Coen R, Molloy AM, Scott J, Cunningham CJ, Lawlor BA, Associations between holotranscobalamin, vitamin B12, homocysteine and depressive symptoms in community-dwelling elders., International journal of geriatric psychiatry, 26, (3), 2011, p307-13 Journal Article, 2011 DOI

Stone N, Pangilinan F, Molloy AM, Shane B, Scott JM, Ueland PM, Mills JL, Kirke PN, Sethupathy P, Brody LC, Bioinformatic and Genetic Association Analysis of MicroRNA Target Sites in One-Carbon Metabolism Genes., PloS One, 6, (7), 2011, pe21851 Journal Article, 2011 TARA - Full Text DOI

Murphy LE, Mills JL, Molloy AM, Qian C, Carter TC, Strevens H, Wide-Swensson D, Giwercman A, Levine RJ, Folate and vitamin B12 in idiopathic male infertility., Asian journal of andrology, 13, (6), 2011, p856-61 Journal Article, 2011 TARA - Full Text DOI

Elizabeth A Yetley, Christine M Pfeiffer, Karen W Phinney, Zia Fazili, David A Lacher, Regan L Bailey, Sheena Blackmore, Jay L Bock, Lawrence C Brody, Ralph Carmel, L Randy Curtin, Ramo"n A Durazo-Arvizu, John H Eckfeldt, Ralph Green, Jesse F Gregory III, Andrew N Hoofnagle, Donald W Jacobsen, Paul F Jacques, Anne M Molloy, Joseph Massaro, James L Mills, Ebba Nexo, Jeanne I Rader, Jacob Selhub, Christopher Sempos, Barry Shane, Sally Stabler, Patrick Stover, Tsunenobu Tamura, Alison Tedstone, Susan J Thorpe, Paul M Coates, Clifford L Johnson, and Mary Frances Picciano, Biomarkers of folate status in NHANES: a roundtable summary 1-6, American Journal of Clinical Nutrition, 94, (1), 2011, 303S-312S Journal Article, 2011 TARA - Full Text

Elizabeth A Yetley, Christine M Pfeiffer, Karen W Phinney, Regan L Bailey, Sheena Blackmore, Jay L Bock, Lawrence C Brody, Ralph Carmel, L Randy Curtin, Ramo"n A Durazo-Arvizu, John H Eckfeldt, Ralph Green, Jesse F Gregory III, Andrew N Hoofnagle, Donald W Jacobsen, Paul F Jacques, David A Lacher, Anne M Molloy, Joseph Massaro, James L Mills, Ebba Nexo, Jeanne I Rader, Jacob Selhub, Christopher Sempos, Barry Shane, Sally Stabler, Patrick Stover, Tsunenobu Tamura, Alison Tedstone, Susan J Thorpe, Paul M Coates, Clifford L Johnson, and Mary Frances Picciano, Biomarkers of vitamin B-12 status in NHANES: a roundtable summary 1-6, American Journal of Clinical Nutrition, 94, (1), 2011, p313S-321S Journal Article, 2011 TARA - Full Text

Valente E, Scott JM, Ueland PM, Cunningham C, Casey M, Molloy AM, Diagnostic accuracy of holotranscobalamin, methylmalonic acid, serum cobalamin, and other indicators of tissue vitamin B12 status in the elderly. , Clinical Chemistry, 57, (6), 2011, p856 - 863 Journal Article, 2011

Tighe P, Ward M, McNulty H, Finnegan O, Dunne A, Strain J, Molloy AM, Duffy M, Pentieva K, Scott JM, A dose-finding trial of the effect of long-term folic acid intervention: implications for food fortification policy, American Journal of Clinical Nutrition, 1-2, 2011, p1-8 Journal Article, 2011 DOI

Pfeiffer CM, Zhang M, Lacher DA, Molloy AM, Tamura T, Yetley EA, Picciano MF, Johnson CL. , Comparison of serum and red blood cell folate microbiologic assays for national population surveys. , Journal of Nutrition, 141, (7), 2011, p1402 - 1409 Journal Article, 2011

Riedel BM, Molloy AM, Meyer K, Fredriksen A, Ulvik A, Schneede J, Nexø E, Hoff G, Ueland PM, Transcobalamin polymorphism 67A->G, but not 776C->G, affects serum holotranscobalamin in a cohort of healthy middle-aged men and women., The Journal of nutrition, 141, (10), 2011, p1784-90 Journal Article, 2011 TARA - Full Text DOI

Robinson DJ, O'Luanaigh C, Tehee E, O'Connell H, Hamilton F, Chin AV, Coen R, Molloy AM, Scott J, Lawlor BA, Cunningham CJ, Vitamin B12 status, homocysteine and mortality amongst community-dwelling Irish elders., Irish journal of medical science, 180, (2), 2011, p451-5 Journal Article, 2011 DOI

Campoy C, Escolano-Margarit MV, Ramos R, Parrilla-Roure M, Csábi G, Beyer J, Ramirez-Tortosa MC, Molloy AM, Decsi T, Koletzko BV, Effects of prenatal fish-oil and 5-methyltetrahydrofolate supplementation on cognitive development of children at 6.5 y of age., The American journal of clinical nutrition, 94, (6 Suppl), 2011, p1880S-1888S Journal Article, 2011 DOI TARA - Full Text

McNulty B, Pentieva K, Marshall B, Ward M, Molloy AM, Scott JM, McNulty H, Women's compliance with current folic acid recommendations and achievement of optimal vitamin status for preventing neural tube defects., Human reproduction (Oxford, England), 26, (6), 2011, p1530-6 Journal Article, 2011 TARA - Full Text DOI

Sutton M, Mills JL, Molloy AM, Troendle JF, Brody LC, Conley M, Mc Donnell R, Scott JM, Kirke PN., Maternal folate, vitamin B12 and homocysteine levels in pregnancies affected by congenital malformations other than neural tube defects. , Birth Defects Research A: Clinical and Molecular Teratology, 91, (7), 2011, p610 - 615 Journal Article, 2011 TARA - Full Text

Mills JL, Carter TC, Scott JM, Troendle JF, Gibney ER, Shane B, Kirke PN, Ueland PM, Brody LC, Molloy AM. , Do high blood folate concentrations exacerbate metabolic abnormalities in people with low vitamin B-12 status? , American Journal of Clinical Nutrition, 94, (2), 2011, p495 - 500 Journal Article, 2011 TARA - Full Text

Carter TC, Pangilinan F, Troendle JF, Molloy AM, VanderMeer J, Mitchell A, Kirke PN, Conley MR, Shane B, Scott JM, Brody LC, Mills JL, Evaluation of 64 candidate single nucleotide polymorphisms as risk factors for neural tube defects in a large Irish study population., American journal of medical genetics. Part A, 155A, (1), 2011, p14-21 Journal Article, 2011 DOI TARA - Full Text

Folate-Vitamin B12 Interrelationships: Links to Disease Risk in, editor(s)L.B. Bailey , Folate in Health and Disease, Second Edition, Boca Raton, FL, Taylor & Francis, 2010, pp381 - 408, [A.M. Molloy] Book Chapter, 2010

Carter TC, Molloy AM, Pangilinan F, Troendle JF, Kirke PN, Conley MR, Orr DJ, Earley M, McKiernan E, Lynn EC, Doyle A, Scott JM, Brody LC, Mills JL, Testing reported associations of genetic risk factors for oral clefts in a large Irish study population., Birth defects research. Part A, Clinical and molecular teratology, 88, (2), 2010, p84-93 Journal Article, 2010 DOI TARA - Full Text

Pangilinan F, Mitchell A, Vandermeer J, Molloy AM, Troendle J, Conley M, Kirke PN, Sutton M, Sequeira JM, Quadros EV, Scott JM, Mills JL, Brody LC, Transcobalamin II receptor polymorphisms are associated with increased risk for neural tube defects., Journal of Medical Genetics, 47, (10), 2010, p677 - 685 Journal Article, 2010 TARA - Full Text DOI

Beaty TH, Murray JC, Marazita ML, Munger RG, Ruczinski I, Hetmanski JB, Liang KY, Wu T, Murray T, Fallin MD, Redett RA, Raymond G, Schwender H, Jin SC, Cooper ME, Dunnwald M, Mansilla MA, Leslie E, Bullard S, Lidral AC, Moreno LM, Menezes R, Vieira AR, Petrin A, Wilcox AJ, Lie RT, Jabs EW, Wu-Chou YH, Chen PK, Wang H, Ye X, Huang S, Yeow V, Chong SS, Jee SH, Shi B, Christensen K, Melbye M, Doheny KF, Pugh EW, Ling H, Castilla EE, Czeizel AE, Ma L, Field LL, Brody L, Pangilinan F, Mills JL, Molloy AM, Kirke PN, Scott JM, Scott JM, Arcos-Burgos M, Scott AF, A genome-wide association study of cleft lip with and without cleft palate identifies risk variants near MAFB and ABCA4., Nature Genetics, 42, (6), 2010, p525-529 Journal Article, 2010 TARA - Full Text DOI

Molloy AM, Quadros EV, Sequeira JM, Troendle JF, Scott JM, Kirke PN, Mills JL., Lack of Association between Folate-Receptor Autoantibodies and Neural-Tube Defects, New England Journal of Medicine, 361, (2), 2009, p152-160 Journal Article, 2009 DOI TARA - Full Text

N. Carroll , F. Pangilinan, A.M. Molloy, J. Troendle, J.L. Mills, P.N. Kirke, L.C. Brody, J.M. Scott, A. Parle-McDermott. , Analysis of the MTHFD1 promoter and risk of neural tube defects., Human Genetics, 125, (3), 2009, p247 - 256 Journal Article, 2009 DOI

L. Hoey, H. McNulty, E.M. McCann, K.J. McCracken, J.M. Scott, B.B. Marc, A.M. Molloy, C. Graham, K.Pentieva, , Laying hens can convert high doses of folic acid added to the feed into natural folates in eggs providing a novel source of food folate, British Journal of Nutrition , 101, (2), 2009, p206 - 212 Journal Article, 2009 DOI

Molloy, A.M., Quadros, E.V., Sequeira, J.M., Troendle, J.F., Scott, J.M., Kirke, P.N., Mills, J.L., Lack of association between folate-receptor autoantibodies and neural-tube defects, Obstetrical and Gynecological Survey, 64, (11), 2009, p716-718 Journal Article, 2009 DOI

Mitchell, A., Pangilinan, F., Van der Meer, J., Molloy, A.M., Troendle, J., Conley, M., Kirke, P.N., Scott, J.M., Brody, L.C., Mills, J.L., Uncoupling protein 2 polymorphisms as risk factors for NTDs, Birth Defects Research Part A: Clinical and Molecular Teratology, 85, (2), 2009, p156 - 160 Journal Article, 2009 DOI

Carroll, N., Pangilinan, F., Molloy, A.M., Troendle, J., Mills, J.L., Kirke, P.N., Brody, L.C., Scott, J.M., Parle-McDermott, A., Analysis of the MTHFD1 promoter and risk of neural tube defects, Human Genetics, 125, (3), 2009, p247 - 256 Journal Article, 2009 DOI TARA - Full Text

A. Mitchell, F. Pangilinan, J.Van der Meer, A.M. Molloy, J. Troendle, M. Conley , P.N. Kirke, J.M. Scott, L.C. Brody, J.L. Mills , Uncoupling protein 2 polymorphisms as risk factors for NTDs, Birth Defects Research Part A Clinical and Molecular Teratology, 85, (2), 2009, p156 - 160 Journal Article, 2009 DOI TARA - Full Text

Molloy, A.M., Kirke, P.N., Troendle, J.F., Burke, H., Sutton, M., Brody, L.C., Scott, J.M., Mills, J.L., Maternal vitamin B12 status and risk of neural tube defects in a population with high neural tube defect prevalence and no folic Acid fortification, Pediatrics, 123, (3), 2009, p917 - 923 Journal Article, 2009 TARA - Full Text DOI

Parle-McDermott A, Pangilinan F, O'Brien KK, Mills JL, Magee AM, Troendle J, Sutton M, Scott JM, Kirke PN, Molloy AM, Brody LC., A common variant in MTHFD1L is associated with neural tube defects and mRNA splicing efficiency, Human Mutation, 30, (12), 2009, p1650-1656 Journal Article, 2009 DOI TARA - Full Text

Molloy, A.M., Brody, L.C., Mills, J.L., Scott, J.M., Kirke, P.N., The search for genetic polymorphisms in the homocysteine/folate pathway that contribute to the etiology of human neural tube defects, Birth Defects Research (Part A), 85, (4), 2009, p285 - 294 Journal Article, 2009

F. Pangilinan, K. Geiler, J. Dolle, J. Troendle, D.A. Swanson, A.M. Molloy, M. Sutton, M. Conley , P.N. Kirke, J.M. Scott, J.L. Mills, L.C. Brody. , Construction of a high resolution linkage disequilibrium map to evaluate common genetic variation in TP53 and neural tube defect risk in an Irish population., American Journal of Medical Genetics A. , 146A, (20), 2008, p2617 - 2625 Journal Article, 2008 DOI TARA - Full Text

J.L. Mills, A.M. Molloy, A. Parle-McDermott, J.F. Troendle, L.C. Brody, M.R. Conley, C. Cox, F. Pangilinan, D.J. Orr, M. Earley, E. McKiernan, E.C. Lynn, A. Doyle, J.M. Scott, P.N. Kirke. , Folate-related gene polymorphisms as risk factors for cleft lip and cleft palate., Birth Defects Research Part A Clinical and Molecular Teratology. , 82, (9), 2008, p636 - 643 Journal Article, 2008 TARA - Full Text DOI

A.M. Molloy, P.N. Kirke, L.C. Brody, J.M. Scott, J.L. Mills , Effects of folate and vitamin B12 deficiencies during pregnancy on fetal, infant, and child development, Food and Nutrition Bulletin , 29, (2 Suppl), 2008, pS101 - S111 Journal Article, 2008

B. Bekaert, M.L. Cooper, F.R. Green, H. McNulty, K. Pentieva, J.M. Scott, A.M. Molloy, M.P. Rayman. , Effect of selenium status and supplementation with high-selenium yeast on plasma homocysteine and B vitamin concentrations in the UK elderly., Molecular Nutrition and Food Research., 52, (11), 2008, p1324 - 1333 Journal Article, 2008 DOI

J.M. Wallace , M.P. Bonham , J. Strain , E.M. Duffy , P.J. Robson , M. Ward , H. McNulty , P.W.Davidson , G.J. Myers , C.F. Shamlaye , T.W. Clarkson, A.M. Molloy, J.M. Scott, P.M. Ueland. , Homocysteine concentration, related B vitamins, and betaine in pregnant women recruited to the Seychelles Child Development Study., American Journal of Clinical Nutrition, 87, (2), 2008, p391 - 397 Journal Article, 2008 TARA - Full Text

J. Little, M. Gilmour, P.A. Mossey, D. Fitzpatrick, A. Cardy, J. Clayton-Smith, A. Hill, S.J. Duthie, A.E. Fryer, A.M. Molloy, J.M. Scott; ITS MAGIC Collaboration. , Folate and clefts of the lip and palate--a U.K.-based case-control study: Part II: Biochemical and genetic analysis, Cleft Palate Craniofacial Journal, 45, (4), 2008, p428 - 438 Journal Article, 2008 DOI

R. Clarke , P. Sherliker, H. Hin, A.M. Molloy, E. Nexo, P.M. Ueland, K. Emmens, J.M. Scott, J.G. Evans. , Folate and vitamin B12 status in relation to cognitive impairment and anaemia in the setting of voluntary fortification in the UK., British Journal of Nutrition, 100, (5), 2008, p1054 - 1059 Journal Article, 2008 DOI

A.V. Chin, D.J. Robinson, H. O'Connell, F. Hamilton , I. Bruce, R. Coen, B. Walsh, D. Coakley, A. Molloy, J. Scott, B.A. Lawlor, C.J. Cunningham. , Vascular biomarkers of cognitive performance in a community-based elderly population: the Dublin Healthy Ageing study. , Age and Ageing , 37, (5), 2008, p559 - 564 Journal Article, 2008 TARA - Full Text DOI

Mary Rose Sweeney, Joseph McPartlin, and John Scott, Folic acid fortification and public health: report on threshold doses above which unmetabolised folic acid appear in serum, BMC Public Health, 7, (41), 2007 Journal Article, 2007 DOI TARA - Full Text

L. Hoey, H. McNulty, N. Askin, A. Dunne, M. Ward, K. Pentieva, J. Strain, A.M. Molloy, C.A. Flynn, J.M. Scott. , Effect of a voluntary food fortification policy on folate, related B vitamin status, and homocysteine in healthy adults., American Journal of Clinical Nutrition, 86, (5), 2007, p1405 - 1413 Journal Article, 2007 TARA - Full Text

R. Clarke, P. Sherliker, H. Hin, E. Nexo, A.M. Hvas, J. Schneede, J. Birks, P.M. Ueland, K. Emmens, J.M. Scott, A.M. Molloy, J.G. Evans. , Detection of vitamin B12 deficiency in older people by measuring vitamin B12 or the active fraction of vitamin B12, holotranscobalamin. , Clinical Chemistry , 53, (5), 2007, p963 - 970 Journal Article, 2007 TARA - Full Text DOI

A. Parle-McDermott, F. Pangilinan, J.L. Mills, P.N. Kirke, E.R. Gibney, J. Troendle, V.B. O'leary, A.M. Molloy, M. Conley, J.M. Scott, L.C. Brody. , The 19-bp deletion polymorphism in intron-1 of dihydrofolate reductase (DHFR) may decrease rather than increase risk for spina bifida in the Irish population., American Journal of Medical Genetics A , 143, (11), 2007, p1174 - 1180 Journal Article, 2007 DOI

M.M. Murphy, A.M. Molloy, P.M. Ueland, J.D. Fernandez-Ballart, J. Schneede, V. Arija, J.M. Scott. , Longitudinal study of the effect of pregnancy on maternal and fetal cobalamin status in healthy women and their offspring., Journal of Nutrition, 137, (8), 2007, p1863 - 1867 Journal Article, 2007 TARA - Full Text

Molloy, A.M., Nutrition and metabolism, 2007, - 372-374 Miscellaneous, 2007 DOI

R. Clarke, J. Birks, E. Nexo, P.M. Ueland, J. Schneede, J. Scott, A. Molloy, J.G. Evans. , Low vitamin B-12 status and risk of cognitive decline in older adults., American Journal of Clinical Nutrition, 86, (5), 2007, p1384 - 1391 Journal Article, 2007 TARA - Full Text

Molloy, A.M., Nutrition and metabolism, 2006, - 477-479 Miscellaneous, 2006 DOI

Parle-McDermott, A., Kirke, P.N., Mills, J.L., Molloy, A.M., Cox, C., O'Leary, V.B., Pangilinan, F., Conley, M., Cleary, L., Brody, L.C., Scott, J.M., , Confirmation of the R653Q polymorphism of the trifunctional C1-synthase enzyme as a maternal risk for neural tube defects in the Irish population., European Journal of Human Genetics, 14, (6), 2006, p768 - 772 Journal Article, 2006 DOI

A. Parle-McDermott, J.L. Mills, A.M. Molloy, N. Carroll, P.N. Kirke, C. Cox, M.R. Conley, F.J. Pangilinan, L.C. Brody, J.M. Scott. , The MTHFR 1298CC and 677TT genotypes have opposite associations with red cell folate levels. , Molecular Genetics and Metabolism , 88, (3), 2006, p290 - 294 Journal Article, 2006 DOI

V.B. O'Leary, F. Pangilinan, C. Cox, A. Parle-McDermott, M. Conley, A.M. Molloy, P.N. Kirke, J.L. Mills, L.C. Brody, J.M. Scott, Reduced folate carrier polymorphisms and neural tube defect risk. , Molecular and Genetic Metabolism. , 87, (4), 2006, p364 - 369 Journal Article, 2006 DOI

H.McNulty, le R.C. Dowey, J.J. Strain, A. Dunne, M. Ward M, A.M. Molloy, L.B. McAnena, J.P. Hughes, M.Hannon-Fletcher, J.M. Scott. , Riboflavin lowers homocysteine in individuals homozygous for the MTHFR 677C->T polymorphism., Circulation, 113, (1), 2006, p74 - 80 Journal Article, 2006 DOI TARA - Full Text

A. Parle-McDermott, P.N. Kirke, J.L.Mills, A.M. Molloy, C.Cox, VB. O'leary, F. Pangilinan, M. Conley, L. Cleary, L.C. Brody, J.M. Scott. , Confirmation of the R653Q polymorphism of the trifunctional C1-synthase enzyme as a maternal risk for neural tube defects in the Irish population. , European Journal of Human Genetics , 14, (6), 2006, p768 - 772 Journal Article, 2006 TARA - Full Text DOI

H. Hin, R. Clarke, P. Sherliker, W. Atoyebi, K. Emmens, J. Birks, J. Schneede, P.M. Ueland, E. Nexo, J. Scott, A. Molloy, M. Donaghy, C. Frost, J.G. Evans. , Clinical relevance of low serum vitamin B12 concentrations in older people: the Banbury B12 study. , Age and Ageing, 35, (4), 2006, p416 - 422 Journal Article, 2006 DOI TARA - Full Text

P.M. Finglas, K. de Meer, A. Molloy, P. Verhoef, K. Pietrzik, H.J. Powers, D. van der Straeten, M. Jagerstad, G. Varela-Moreiras, T. van Vliet, R. Havenaar, J. Buttriss, A.J. Wright. , Research goals for folate and related B vitamin in Europe., European Journal of Clinical Nutrition, 60, (2), 2006, p287 - 294 Journal Article, 2006 DOI

M.A. Mohammad, A. Molloy, J. Scott, L. Hussein. , Plasma cobalamin and folate and their metabolic markers methylmalonic acid and total homocysteine among Egyptian children before and after nutritional supplementation with the probiotic bacteria Lactobacillus acidophilus in yoghurt matrix. , International Journal of Food Science and Nutrition , 57, (7-8), 2006, p470 - 480 Journal Article, 2006 DOI

M. Klingler, A. Blaschitz, C. Campoy, A. Cano, A.M. Molloy, J.M. Scott, G. Dohr, H. Demmelmair, B. Koletzko, G. Desoye. , The effect of docosahexaenoic acid and folic acid supplementation on placental apoptosis and proliferation. , British Journal of Nutrition, 96, (1), 2006, p182 - 190 Journal Article, 2006 DOI

McNulty, H., Dowey, L.R.C., Strain, J.J., Ward, M., McAnena, L.B., Hughes, J.P., Hannon-Fletcher, M., (...), Scott, J.M., Response to letter regarding article, "riboflavin lowers homocysteine in individuals homozygous for the MTHFR 677C→T polymorphism" [2] , 2006, - e66 Miscellaneous, 2006 DOI

V.B. O'Leary, J.L. Mills, A. Parle-McDermott, F. Pangilinan, A.M. Molloy, C. Cox, A. Weiler, M. Conley, P.N. Kirke, J.M. Scott, L.C. Brody; Birth Defects Research Group. , Screening for new MTHFR polymorphisms and NTD risk., American Journal of Medical Genetics A, 138, (2), 2005, p99 - 106 Journal Article, 2005 DOI

V.B. O'Leary, J.L. Mills, F. Pangilinan, P.N. Kirke, C. Cox, M. Conley, A. Weiler, K. Peng, B. Shane, J.M. Scott, A. Parle-McDermott, A.M. Molloy, L.C. Brody; Members of the Birth Defects Research Group, Analysis of methionine synthase reductase polymorphisms for neural tube defects, Molecular Genetics and Metabolism, 85, (3), 2005, p220 - 227 Journal Article, 2005 DOI

D.A. Swanson, F. Pangilinan, J.L. Mills,P.N. Kirke, M. Conley, A. Weiler, T. Frey, A. Parle-McDermott, V.B. O'Leary, R.R. Seltzer, K.A. Moynihan, A.M. Molloy, H. Burke, J.M. Scott, L.C. Brody. , Evaluation of transcobalamin II polymorphisms as neural tube defect risk factors in an Irish population., Birth Defects Research A: Clinical and Molecular Teratology , 73, (4), 2005, p239 - 244 Journal Article, 2005 DOI

A. Parle-McDermott, F. Pangilinan, J.L. Mills, C.C. Signore, A.M. Molloy, A. Cotter, M. Conley, C. Cox, P.N. Kirke, J.M. Scott, L.C. Brody., A polymorphism in the MTHFD1 gene increases a mother's risk of having an unexplained second trimester pregnancy loss., Molecular Human Reproduction, 11, 2005, p477 - 480 Journal Article, 2005 DOI TARA - Full Text

S. Daly, A. Cotter, A. Molloy, J. Scott. , Homocysteine and folic acid: implications for pregnancy., Seminars in Vascular Medicine., 5, (2), 2005, p190-200 Review, 2005 DOI

A.L. Morkbak, R.M. Heimdal, K. Emmens, A. Molloy, A.M. Hvas, J. Schneede, R. Clarke, J.M. Scott, P.M. Ueland, E. Nexo. , Evaluation of the technical performance of novel holotranscobalamin (holoTC) assays in a multicenter European demonstration project., Clinical Chemistry and Laboratory Medicine, 43, (10), 2005, p1058 - 1064 Journal Article, 2005 DOI

A. Parle-McDermott, J.L. Mills, P.N. Kirke, C. Cox, C.C. Signore, S. Kirke, A.M. Molloy, V.B. O'Leary, F.J. Pangilinan, C. O'Herlihy, L.C. Brody, J.M. Scott., MTHFD1 R653Q polymorphism is a maternal genetic risk factor for severe abruption placentae., American Journal of Medical Genetics A., 132, 2005, p365 - 368 Journal Article, 2005 DOI

Molloy, A.M., The role of folic acid in the prevention of neural tube defects , Trends in Food Science and Technology, 16, (6-7), 2005, p241-245 Journal Article, 2005 DOI

A.M. Molloy, J.L. Mills, C. Cox, S.F. Daly, M. Conley, L.C. Brody, P.N. Kirke, J.M. Scott, P.M. Ueland. , Choline and homocysteine interrelations in umbilical cord and maternal plasma at delivery., American Journal of Clinical Nutrition , 82, (4), 2005, p836 - 842 Journal Article, 2005 TARA - Full Text

Pentieva K, McNulty H, Reichert R, Ward M, Strain JJ, McKillop DJ, McPartlin JM, Connolly E, Molloy A, Kramer K, Scott JM., The short-term bioavailabilities of [6S]-5-methyltetrahydrofolate and folic acid are equivalent in men., Journal of Nutrition , 134, (3), 2004, p580 - 585 Journal Article, 2004 TARA - Full Text

M.P. Hannon-Fletcher, N.C. Armstrong, J.M. Scott, K. Pentieva, I. Bradbury, M. Ward, J.J. Strain, A.A. Dunn, A.M. Molloy, M.A. Kerr, H. McNulty, Determining bioavailability of food folates in a controlled intervention study, American Journal of Clinical Nutrition, 80, 2004, p911 - 918 Journal Article, 2004 TARA - Full Text

P.N. Kirke, J.L. Mills, A.M. Molloy, L.C. Brody, V.B. O'Leary, L. Daly, S. Murray, M. Conley, P.D. Mayne, O. Smith, J.M. Scott. , Impact of the MTHFR C677T polymorphism on risk of neural tube defects:case-control study, British Medical Journal, 328, 2004, p1535 - 1536 Journal Article, 2004 TARA - Full Text DOI

A.M. Molloy , Folate and Homocysteine Interrelationships including genetics of the relevant enzymes., Current Opinions in Lipidology, 15, 2004, p49-57. Review, 2004 DOI

A.M. Molloy, Genetic variation and nutritional requirements, World Review of Nutrition and Dietetics, 93, 2004, p153-63 Review, 2004

M.M. Murphy, J.M. Scott, V. Arija, A.M. Molloy, J.D. Fernandez-Ballart., Maternal homocysteine before conception and throughout pregnancy predicts fetal homocysteine and birth weight., Clinical Chemistry., 50, 2004, p1406 - 1412 Journal Article, 2004 DOI

A. Parle-McDermott, E. J. McManus, J. L. Mills, V. B. O'Leary, F. Pangilinan, C. Cox, A. Weiler, A. M. Molloy, M. Conley, D. Watson, J. M. Scott, L. C. Brody and P. N. Kirke, Polymorphisms within the vitamin B12 dependent methylmalonyl-coA mutase are not risk factors for neural tube defects, Molecular Genetics and Metabolism, 80, (4), 2003, p463-8 Journal Article, 2003 DOI URL

V. B. O'Leary, J. L. Mills, P. N. Kirke, A. Parle-McDermott, D. A. Swanson, A. Weiler, F. Pangilinan, M. Conley, A. M. Molloy, M. Lynch, C. Cox, J. M. Scott and L. C. Brody, Analysis of the human folate receptor beta gene for an association with neural tube defects, Molecular genetics and metabolism, 79, (2), 2003, p129-133 Journal Article, 2003 DOI

A. M. Cotter, A. M. Molloy, J. M. Scott and S. F. Daly, Elevated plasma homocysteine in early pregnancy: a risk factor for the development of nonsevere preeclampsia, American Journal of Obstetrics and Gynecology, 189, (2), 2003, p391-394 Journal Article, 2003 DOI URL

A. Parle-McDermott, J. L. Mills, P. N. Kirke, V. B. O'Leary, D. A. Swanson, F. Pangilinan, M. Conley, A. M. Molloy, C. Cox, J. M. Scott and L. C. Brody, Analysis of the MTHFR 1298A-->C and 677C-->T polymorphisms as risk factors for neural tube defects, Journal of Human Genetics, 48, (4), 2003, p190-193 Journal Article, 2003 DOI

A. M. Molloy, J. L. Mills, J. McPartlin, P. N. Kirke, J. M. Scott and S. Daly, Maternal and fetal plasma homocysteine concentrations at birth: the influence of folate, vitamin B12, and the 5,10-methylenetetrahydrofolate reductase 677C-->T variant, American journal of obstetrics and gynecology, 186, (3), 2002, p499-503 Journal Article, 2002 DOI URL

V. B. O'Leary, A. Parle-McDermott, A. M. Molloy, P. N. Kirke, Z. Johnson, M. Conley, J. M. Scott and J. L. Mills, MTRR and MTHFR polymorphism: link to Down syndrome?, American Journal of Medical Genetics, 107, (2), 2002, p151-155 Journal Article, 2002 DOI URL

Molloy, A.M, Folate bioavailability and health, International Journal for Vitamin and Nutrition Research , 72, (1), 2002, 46-52 Journal Article, 2002

S. Daly, J. L. Mills, A. M. Molloy, M. Conley, J. McPartlin, Y. J. Lee, P. B. Young, P. N. Kirke, D. G. Weir and J. M. Scott, Low-dose folic acid lowers plasma homocysteine levels in women of child-bearing age, QJM - Monthly Journal of the Association of Physicians , 95, (11), 2002, p733-740 Journal Article, 2002 URL

L. C. Brody, M. Conley, C. Cox, P. N. Kirke, M. P. McKeever, J. L. Mills, A. M. Molloy, V. B. O'Leary, A. Parle-McDermott, J. M. Scott and D. A. Swanson, A polymorphism, R653Q, in the trifunctional enzyme methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase/formyltetrahydrofolate synthetase is a maternal genetic risk factor for neural tube defects: report of the Birth Defects Research Group, American Journal of Human Genetics, 71, (5), 2002, p1207-1215 Journal Article, 2002 TARA - Full Text DOI

A. M. Cotter, A. M. Molloy, J. M. Scott and S. F. Daly, Elevated plasma homocysteine in early pregnancy: a risk factor for the development of severe preeclampsia, American journal of obstetrics and gynecology, 185, (4), 2001, p781-5 Journal Article, 2001 URL DOI

B. M. Ryan, A. M. Molloy, R. McManus, Q. Arfin, D. Kelleher, J. M. Scott and D. G. Weir, The methylenetetrahydrofolate reductase (MTHFR) gene in colorectal cancer: role in tumor development and significance of allelic loss in tumor progression, International journal of gastrointestinal cancer, 30, (3), 2001, p105-111 Journal Article, 2001 DOI URL

Molloy, A.M., Role of genetic variation in establishing nutritional requirements: folate, a case in point., World Review of Nutrition and Dietetics, 89, 2001, p68-75 Journal Article, 2001

A. M. Molloy and J. M. Scott, Folates and prevention of disease, Public Health Nutrition, 4, (2B), 2001, p601-609 Journal Article, 2001 URL DOI

Weir DG, Molloy AM., Microvascular disease and dementia in the elderly: Are they related to hyperhomocysteinemia, 2000, - 859-860 Miscellaneous, 2000 URL

D. C. Shields, D. Ramsbottom, C. Donoghue, E. Pinjon, P. N. Kirke, A. M. Molloy, Y. H. Edwards, J. L. Mills, L. Mynett-Johnson, D. G. Weir, J. M. Scott and A. S. Whitehead, Association between historically high frequencies of neural tube defects and the human T homologue of mouse T (Brachyury), American Journal of Medical Genetics, 92, (3), 2000, p206-211 Journal Article, 2000 DOI URL

Molloy, A.M., Is impaired folate absorption a factor in neural tube defects? Editorial, 2000, - 3-4 Miscellaneous, 2000

A. S. Whitehead, A. M. Molloy, D. Ramsbottom, D. G. Weir, P. N. Kirke, J. L. Mills, P. M. Gallagher and J. M. Scott, Gene-gene interactions and neural tube defects, Clinical Genetics, 55, (2), 1999, p133-134 Journal Article, 1999 URL DOI

A. M. Molloy, D. G. Weir and J. M. Scott, Homocysteine, folate enzymes and neural tube defects, Haematologica, 84 Suppl , (EHA-4), 1999, p53-56 Journal Article, 1999

L. C. Brody, P. J. Baker, P. S. Chines, A. Musick, A. M. Molloy, D. A. Swanson, P. N. Kirke, S. Ghosh, J. M. Scott and J. L. Mills, Methionine synthase: high-resolution mapping of the human gene and evaluation as a candidate locus for neural tube defects, Molecular Genetics and Metabolism, 67, (4), 1999, p324-333 Journal Article, 1999 DOI

S. F. Daly, A. M. Molloy, J. L. Mills, Y. J. Lee, M. Conley, P. N. Kirke, D. G. Weir and J. M. Scott, The influence of 5,10 methylenetetrahydrofolate reductase genotypes on enzyme activity in placental tissue, British Journal of Obstetrics and Gynaecology, 106, (11), 1999, p1214-1218 Journal Article, 1999 URL

D. C. Shields, P. N. Kirke, J. L. Mills, D. Ramsbottom, A. M. Molloy, H. Burke, D. G. Weir, J. M. Scott and A. S. Whitehead, The "thermolabile" variant of methylenetetrahydrofolate reductase and neural tube defects: An evaluation of genetic risk and the relative importance of the genotypes of the embryo and the mother, American Journal of Human Genetics, 64, (4), 1999, p1045-1055 Journal Article, 1999 URL DOI TARA - Full Text

N. Mahmud, A. Molloy, J. McPartlin, R. Corbally, A. S. Whitehead, J. M. Scott and D. G. Weir, Increased prevalence of methylenetetrahydrofolate reductase C677T variant in patients with inflammatory bowel disease, and its clinical implications, Gut, 45, (3), 1999, p389-94 Journal Article, 1999 DOI

J. L. Mills, P. N. Kirke, A. M. Molloy, H. Burke, M. R. Conley, Y. J. Lee, P. D. Mayne, D. G. Weir and J. M. Scott, Methylenetetrahydrofolate reductase thermolabile variant and oral clefts, American Journal of Medical Genetics, 86, (1), 1999, p71-74 Journal Article, 1999 DOI

A. M. Molloy, J. L. Mills, P. N. Kirke, D. G. Weir and J. M. Scott, Folate status and neural tube defects, BioFactors (Oxford, England), 10, (2-3), 1999, p291-294 Journal Article, 1999 URL

A. M. Molloy, J. L. Mills, P. N. Kirke, A. S. Whitehead, D. G. Weir and J. M. Scott, Whole-blood folate values in subjects with different methylenetetrahydrofolate reductase genotypes: differences between the radioassay and microbiological assays, Clinical Chemistry, 44, (1), 1998, p186-188 Journal Article, 1998 URL

Wald, N.J., Law, M., Jordan, R., Schorah, C.J., Daly, S., Mills, J., Molloy, A., (...), Scott, J., Folic acid food fortification to prevent neural tube defects (multiple letters) [6], 1998, - 834-835 Miscellaneous, 1998

A. M. Molloy, J. L. Mills, P. N. Kirke, D. Ramsbottom, J. M. McPartlin, H. Burke, M. Conley, A. S. Whitehead, D. G. Weir and J. M. Scott, Low blood folates in NTD pregnancies are only partly explained by thermolabile 5,10-methylenetetrahydrofolate reductase: low folate status alone may be the critical factor, American Journal of Medical Genetics, 78, (2), 1998, p155-159 Journal Article, 1998 DOI URL

D. Ramsbottom, J. M. Scott, A. Molloy, D. G. Weir, P. N. Kirke, J. L. Mills, P. M. Gallagher and A. S. Whitehead, Are common mutations of cystathionine beta-synthase involved in the aetiology of neural tube defects?, Clinical Genetics, 51, (1), 1997, p39-42 Journal Article, 1997 URL

A. M. Molloy and J. M. Scott, Microbiological assay for serum, plasma, and red cell folate using cryopreserved, microtiter plate method, Methods in enzymology, 281, 1997, p43-53 Journal Article, 1997 DOI

S. Daly, J. L. Mills, A. M. Molloy, M. Conley, Y. J. Lee, P. N. Kirke, D. G. Weir and J. M. Scott, Minimum effective dose of folic acid for food fortification to prevent neural-tube defects, Lancet, 350, (9092), 1997, p1666-1669 Journal Article, 1997 DOI

A. M. Molloy, S. Daly, J. L. Mills, P. N. Kirke, A. S. Whitehead, D. Ramsbottom, M. R. Conley, D. G. Weir and J. M. Scott, Thermolabile variant of 5,10-methylenetetrahydrofolate reductase associated with low red-cell folates: implications for folate intake recommendations, Lancet, 349, (9065), 1997, p1591-3 Journal Article, 1997 URL

P. B. Young, S. Kennedy, A. M. Molloy, J. M. Scott, D. G. Weir and D. G. Kennedy, Lipid peroxidation induced in vivo by hyperhomocysteinaemia in pigs, Atherosclerosis, 129, (1), 1997, p67-71 Journal Article, 1997 DOI

J. L. Mills, J. M. Scott, P. N. Kirke, J. M. McPartlin, M. R. Conley, D. G. Weir, A. M. Molloy and Y. J. Lee, Homocysteine and neural tube defects, The Journal of nutrition, 126, (3), 1996, p756S-760S Journal Article, 1996 URL

P. N. Kirke, L. E. Daly, A. Molloy, D. G. Weir and J. M. Scott, Maternal folate status and risk of neural tube defects, Lancet, 348, (9019), 1996, p67-8 Journal Article, 1996 URL

P. N. Kirke, J. L. Mills, A. S. Whitehead, A. Molloy and J. M. Scott, Methylenetetrahydrofolate reductase mutation and neural tube defects, Lancet, 348, (9033), 1996, p1037-8 Journal Article, 1996 URL

M. McKeever, A. Molloy, D. G. Weir, P. B. Young, D. G. Kennedy, S. Kennedy and J. M. Scott, An abnormal methylation ratio induces hypomethylation in vitro in the brain of pig and man, but not in rat, Clinical science , 88, (1), 1995, p73-79 Journal Article, 1995 URL URL

A. S. Whitehead, P. Gallagher, J. L. Mills, P. N. Kirke, H. Burke, A. M. Molloy, D. G. Weir, D. C. Shields and J. M. Scott, A genetic defect in 5,10 methylenetetrahydrofolate reductase in neural tube defects, QJM, 88, (11), 1995, p763-766 Journal Article, 1995 URL DOI

L. E. Daly, P. N. Kirke, A. Molloy, D. G. Weir and J. M. Scott, Folate levels and neural tube defects. Implications for prevention, JAMA, 274, (21), 1995, p1698-702 Journal Article, 1995 URL

P. B. Young, S. Kennedy, A. M. Molloy, J. M. Scott, D. G. Weir and D. G. Kennedy, Effect of N2O treatment/vitamin B12 deficiency in pigs on tissue concentrations of odd-numbered, branched-chain fatty acids, International journal for vitamin and nutrition research Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung Journal international de vitaminologie et de nutrition, 65, (4), 1995, p255-60 Journal Article, 1995 URL

D. G. Kennedy, P. B. Young, S. Kennedy, J. M. Scott, A. M. Molloy, D. G. Weir and J. Price, Cobalt-vitamin B12 deficiency and the activity of methylmalonyl CoA mutase and methionine synthase in cattle, International journal for vitamin and nutrition research Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung Journal international de vitaminologie et de nutrition, 65, (4), 1995, p241-247 Journal Article, 1995 URL

M. McKeever, A. Molloy, P. Young, S. Kennedy, D. G. Kennedy, J. M. Scott and D. G. Weir, Demonstration of hypomethylation of proteins in the brain of pigs (but not in rats) associated with chronic vitamin B12 inactivation, Clinical science, 88, (4), 1995, p471-477 Journal Article, 1995 URL

J. M. Scott, A. M. Molloy, D. G. Kennedy, S. Kennedy and D. G. Weir, Effects of the disruption of transmethylation in the central nervous system: an animal model, Acta neurologica Scandinavica Supplementum, 154, 1994, p27-31 Journal Article, 1994 URL

J. M. Scott, D. G. Weir, A. Molloy, J. McPartlin, L. Daly and P. Kirke, Folic acid metabolism and mechanisms of neural tube defects, Ciba Foundation symposium, 181, 1994, p180-187 Journal Article, 1994 URL

D. G. Kennedy, P. B. Young, W. J. Blanchflower, J. M. Scott, D. G. Weir, A. M. Molloy and S. Kennedy, Cobalt-vitamin B12 deficiency causes lipid accumulation, lipid peroxidation and decreased alpha-tocopherol concentrations in the liver of sheep, International journal for vitamin and nutrition research Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung Journal international de vitaminologie et de nutrition, 64, (4), 1994, p270-276 Journal Article, 1994 URL

G. O'Connor, A. M. Molloy, L. Daly and J. M. Scott, Deriving a useful packed cell volume estimate from haemoglobin analysis, Journal of Clinical Pathology, 47, (1), 1994, p78-79 Journal Article, 1994 DOI TARA - Full Text

D. G. Kennedy, S. Kennedy, W. J. Blanchflower, J. M. Scott, D. G. Weir, A. M. Molloy and P. B. Young, Cobalt-vitamin B12 deficiency causes accumulation of odd-numbered, branched-chain fatty acids in the tissues of sheep, The British Journal of Nutrition, 71, (1), 1994, p67-76 Journal Article, 1994 DOI

K. C. Trimble, A. M. Molloy, J. M. Scott and D. G. Weir, The effect of ethanol on one-carbon metabolism: increased methionine catabolism and lipotrope methyl-group wastage, Hepatology , 18, (4), 1993, p984-989 Journal Article, 1993 DOI

J. M. Scott, J. McPartlin, A. Molloy, H. McNulty, A. Halligan, M. Darling and D. G. Weir, Folate metabolism in pregnancy, Advances in experimental medicine and biology, 338, 1993, p727-32 Journal Article, 1993 URL

K. C. Trimble, M. G. Goggins, A. M. Molloy, F. Mulcahy, J. M. Scott and D. G. Weir, Vitamin B12 deficiency is not a cause of HIV-associated neuropathy, AIDS (London, England), 7, (8), 1993, p1132-1133 Journal Article, 1993 URL

P. N. Kirke, A. M. Molloy, L. E. Daly, H. Burke, D. G. Weir and J. M. Scott, Maternal plasma folate and vitamin B12 are independent risk factors for neural tube defects, The Quarterly Journal of Medicine, 86, (11), 1993, p703-708 Journal Article, 1993 URL

D. G. Kennedy, W. J. Blanchflower, J. M. Scott, D. G. Weir, A. M. Molloy, S. Kennedy and P. B. Young, Cobalt-vitamin B-12 deficiency decreases methionine synthase activity and phospholipid methylation in sheep, The Journal of Nutrition, 122, (7), 1992, p1384-1390 Journal Article, 1992 URL

D. G. Weir, A. M. Molloy, J. N. Keating, P. B. Young, S. Kennedy, D. G. Kennedy and J. M. Scott, Correlation of the ratio of S-adenosyl-L-methionine to S-adenosyl-L-homocysteine in the brain and cerebrospinal fluid of the pig: implications for the determination of this methylation ratio in human brain, Clinical Science, 82, (1), 1992, p93-97 Journal Article, 1992 URL

A. M. Molloy, B. Orsi, D. G. Kennedy, S. Kennedy, D. G. Weir and J. M. Scott, The relationship between the activity of methionine synthase and the ratio of S-adenosylmethionine to S-adenosylhomocysteine in the brain and other tissues of the pig, Biochemical pharmacology, 44, (7), 1992, p1349-55 Journal Article, 1992 DOI

M. P. McKeever, D. G. Weir, A. Molloy and J. M. Scott, Betaine-homocysteine methyltransferase: organ distribution in man, pig and rat and subcellular distribution in the rat, Clinical Science, 81, (4), 1991, p551-556 Journal Article, 1991 URL

A. M. Molloy, D. G. Weir, G. Kennedy, S. Kennedy and J. M. Scott, A new high performance liquid chromatographic method for the simultaneous measurement of S-adenosylmethionine and S-adenosylhomocysteine. Concentrations in pig tissues after inactivation of methionine synthase by nitrous oxide, Biomedical Chromatography, 4, (6), 1990, p257-260 Journal Article, 1990 DOI

D. G. Weir, S. Keating, A. Molloy, J. McPartlin, S. Kennedy, J. Blanchflower, D. G. Kennedy, D. Rice and J. M. Scott, Methylation deficiency causes vitamin B12-associated neuropathy in the pig, Journal of Neurochemistry, 51, (6), 1988, p1949-1952 Journal Article, 1988 URL DOI

Non-Peer-Reviewed Publications

Molloy AM, Pentieva K, McNulty B, McNulty H., Reply to SW D'Souza et al, American Journal of Clinical Nutrition, 98, (6), 2013, p1598 - 1598 Journal Article, 2013

A.M. Molloy, J.M. Scott., Nutrition and metabolism., Current Opinions in Lipidology , 16, (4), 2005, p494-496 Review, 2005

Research Expertise

Description

. The role of folate and vitamin B12 in pregnancy: This incorporates two principal areas; (1) the cause of folate responsive neural tube defects, in particular the nutritional, biochemical and genetic parameters associated with these disorders and (2) the effects of inadequate folate or vitamin B12 nutrition on complications of pregnancy and adverse pregnancy outcomes. The role of these vitamins in other congenital disorders including oro-facial clefts and congenital heart disease is an extension of this area of interest. . The uptake and utilisation of folates in normal and deficient states: A particular area of interest is the effect of genetic variants in folate related enzymes on folate status and metabolism. Research methods include cell culture studies and studies on nutritional status in human subjects, stratified according to a genotype of interest. . The development and application of new techniques in the analysis of folates and folate related metabolites. including HPLC methods, amino acid analysis, radioisotope methods, microbiological assays and cell culture technology. . Links between folate and vitamin B12; specifically, the influence of folate and vitamin B12 status on methylation reactions and s-adenosylmethionine metabolism.

Keywords

Age related diseases; Folate, Vitamin B12; Metabolism and metabolic diseases; Molecular nutrition; Population based intervention trials

Recognition

Representations

Folic acid Review Group, organized by Food Safety authority of Ireland, Ireland September 2014-ongoing

Expert Advisor WHO guideline development meeting on 'Optimal blood folate concentrations in women of reproductive age for prevention on Folate and Vitamin B12 deficiencies' September 2013

Research Ethics Committee, Coombe womens' Hospital 2002-2012

Editorial Board, British Journal of Nutrition 2004-2009

Expert Advisor at the Biomarkers of Nutrition for Development (BOND) Vitamin B12 Consultation, Office of Dietary Supplements, NIH, Washington, December 2012

Expert Advisor at the Biomarkers of Nutrition for Development (BOND) Vitamin B12 Consultation, Office of Dietary Supplements, NIH, Washington, September 2012

Expert Panel for the project "Identifying Research Needs for Assessing Safe Use of High Intakes of Folic Acid" organized by the Office of Health Assessment and Translation, (NIEHS and ODS, National Institutes of Health, USA) 2014-2015

WHO Technical Consultant on Folate and Vitamin B12 Deficiencies October 2005

Expert advisor at the NHANES Folate and Vitamin B12 Assessment Round-Table meeting hosted by the Office of Dietary Supplements, NIH, Washington, 15th -16th July 2010

Meeting Chair and Expert advisor at the World health Organization/Centers for Disease Control (WHO/CDC) Technical Consultation on "Optimal blood folate concentrations in women of reproductive age for prevention of neural tube defects" Atlanta, Georgia, USA . August 2012

Member of the planning committee (coordinator Professor Lindsay Allen, University of California, Davis) for Track 2 of the Micronutrient Forum Conference, held in Addis Ababa, Ethiopia, June 2014 2013-2014

Awards and Honours

Fellow, Trinity College Dublin 2015

Global Experts Network on Spina Bifida and Hydrocephalus 2014

Memberships

The Biochemical Society 1976 – 2008

The Nutrition Society 2005 – date

American society of Nutrition 2011 – date