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The Discipline of Radiation Therapy was originally opened in 1983 under the auspices of the UK College of Radiographers and was sited at St. Luke's Hospital, Dublin, with successful students obtaining the Diploma of the UK College of Radiographers.

In 1990 discussions began on the development of a university degree programme. These were successfully concluded with the commencement of the Honours B.Sc. degree course at Trinity College Dublin in 1993. Between 1993 and 1999 the average student intake of the department was 8-10 students with 3 staff members.

Following recommendations of the National Expert Working Group on Radiation Oncology Services the annual student intake increased to 15 in 2001 and to 25 from 2002. In addition, the Discipline’s staff complement has increased to 8 full time lecturers with a considerably expanded skill mix and professional background that reflects the multidisciplinary nature of the degree programme.

In 2002, the National Expert Working Group recommended that the professional title of Radiation Therapist be adopted. The title of the Discipline and the degree awarded has been changed accordingly. The Discipline provides the only course in Radiation Therapy in the Republic of Ireland and is therefore providing a national service. During 2003 the department relocated to the new Trinity Centre for Health Sciences.

The Discipline has developed significant international links over many years including the Radiation Oncology Branch (ROB) and Radiation Oncology Sciences Programme (ROSP) at the National Institute of Health (NIH) in Washington DC, the European Society for Therapeutic Radiotherapy and Oncology (ESTRO) and the Dresden Centre for Radiation Research in Oncology (ZIK Dresden).