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Recent Publications

Type Reference Status
Journal Article C. Dempsey, A. Rubio Araiz, K. J. Bryson, O. Finucane, C. Larkin, E. L. Mills, A. A. B. Robertson, M. A. Cooper, L. A. J. O'Neill and M. A. Lynch, Inhibiting the NLRP3 inflammasome with MCC950 promotes non-phlogistic clearance of amyloid-β and cognitive function in APP/PS1 mice, Brain, Behaviour and Immunity PUBLISHED
Journal Article Karok,S., Fletcher, D., Witney, A.G., Task-specificity of unilateral anodal and dual-M1 tDCS effects on motor learning, Neuropsychologia, 94, 2017, p84 - 95 PUBLISHED
Journal Article Karok, S., Witney, A.G., Topical issues of transcranial direct current stimulation usage revealed through a cross-sectional university-wide survey, Journal of Cognition and Neuroethics, 4, (3), 2017, p1 - 32 PUBLISHED
Journal Article Fitzpatrick, J-M., Downer, E.J., Toll-like Receptor Signalling as a Cannabinoid Target in Multiple Sclerosis. , Neuropharmacology. , 113(Pt B), 2017, p618 - 626 PUBLISHED
Journal Article Lone, M., McKenna, J.P., Cryan, J.F., Downer, E.J., Toulouse, A. , Assessment of Thiel-embalmed cadavers as a teaching tool for oral anatomy and local anaesthesia., J Dent Education, [in press], 2017 PUBLISHED
Type Reference Status
Journal Article Crowley T, Cryan JF, Downer EJ, O'Leary OF, Inhibiting Neuroinflammation: The Role and Therapeutic Potential of Gaba in Neuro-Immune Interactions., Brain, behavior, and immunity, 2016 PUBLISHED
Journal Article Fallarino F, Gargaro M, Mondanell G, Downer EJ, Hossain MJ, Gran B, Delineating the Role of Toll-Like Receptors in the Neuro-inflammation Model EAE., Methods in molecular biology (Clifton, N.J.), 1390, 2016, p383-411 PUBLISHED
Journal Article Ryan SM, Kelly ÁM, Exercise as a pro-cognitive, pro-neurogenic and anti-inflammatory intervention in transgenic mouse models of Alzheimer's disease., Ageing research reviews, 27, 2016, p77-92 PUBLISHED
Journal Article Drechsler S, Lynch M.A, Novella S, González-Navarro H, Hecimovic S, Barini E, Tucci V, Castro R.E, Vandenbroucke R.E, Osuchowski M, Potter P.K, With mouse age comes wisdom: A review and suggestions of relevant mouse models for age-related conditions, Mechanisms of Ageing and Development, 160, 2016, p54 - 68 PUBLISHED
Journal Article Lyons A, Minogue A.M, Jones R.S, Fitzpatrick O, Noonan J, Campbell V.A, Lynch M.A, Analysis of the Impact of CD200 on Phagocytosis, Molecular Neurobiology, 2016, p1-10 In_Press
Journal Article McDonald C.L, Hennessy E, Rubio-Araiz A, Keogh B, McCormack W, McGuirk P, Reilly M, Lynch M.A, Inhibiting TLR2 activation attenuates amyloid accumulation and glial activation in a mouse model of Alzheimer's disease, Brain, Behavior, and Immunity, 58, 2016, p191 - 200 PUBLISHED
Journal Article Andreasson K.I, Bachstetter A.D, Colonna M, Ginhoux F, Holmes C, Lamb B, Landreth G, Lee D.C, Low D, Lynch M.A, Monsonego A, O'Banion M.K, Pekny M, Puschmann T, Russek-Blum N, Sandusky L.A, Selenica M.-L.B, Takata K, Teeling J, Town T, Van Eldik L.J, Targeting innate immunity for neurodegenerative disorders of the central nervous system, Journal of Neurochemistry, 2016, p653 - 693 PUBLISHED
Journal Article Costello D.A, Keenan K, McManus R.M, Falvey A, Lynch M.A, The age-related neuroinflammatory environment promotes macrophage activation, which negatively impacts synaptic function, Neurobiology of Aging, 43, 2016, p140 - 148 PUBLISHED
Journel Article McDermott A, Zaporojan L, McNamara P, Doherty C.P, Redmond J, Forde C, Gormley J, Egaña M, Bergin C, The effects of a 16-week aerobic exercise programme on cognitive function in people living with HIV, AIDS Care , 2016, p1-8 In_Press
Journal Article Barry, A., Cronin, O, Ryan, A.M., Sweeney, B., Yap, S., O’Toole, O., Allen, A.P., Clarke, G., O’Halloran, K.D., and Downer, E.J., Impact of Exercise on Innate Immunity in Multiple Sclerosis Progression and Symptomatology., Frontiers in Physiology. , 7, 2016, p194- PUBLISHED
Journal Article McCarthy A, Mulligan J, Egaña M, Postexercise cold-water immersion improves intermittent high-intensity exercise performance in normothermia, Applied Physiology, Nutrition, and Metabolism, 41, (11), 2016, p1163 - 1170 PUBLISHED
Type Reference Status
Book Chapter Non-pharmacological Approaches to Cognitive Enhancement in, editor(s)Kantak, K.M.; Wettstein, J.G. , Handbook of Experimental Pharmacology: Cognitive Enhancement, Springer Biomedicine, 2015, pp417 - 439, [Kelly, A.M.] PUBLISHED
Conference Paper Sophia Karok, David Fletcher, Alice Witney, Single session of tDCS transiently enhances movement speed in a motor task for the whole lower limb, Brain Stimulation, 01/03/2015, 2015 PUBLISHED
Journal Article Lynch, MA, Bone Marrow-Derived Macrophages from AβPP/PS1 Mice are Sensitized to the Effects of Inflammatory Stimuli., Journal of Alzheimers Disease, 44 , (3), 2015, p949-962 PUBLISHED
Journal Article Lynch, MA, α-TLR2 antibody attenuates the Aβ-mediated inflammatory response in microglia through enhanced expression of SIGIRR. , Brain Behaviour Immunity, 46, 2015, p70–79 PUBLISHED
Journal Article O'Connor E, Green S, Kiely C, O'Shea D and Egaña M., Differential effects of age and type 2 diabetes on dynamic versus peak response of pulmonary oxygen uptake during exercise., Journal of Applied Physiology, 118, (8), 2015, p1031 - 1039 PUBLISHED
Journal Article Green S, Egaña M, Baldi JC, Lamberts R and Regensteiner JG, Cardiovascular Control during Exercise in Type 2 Diabetes Mellitus, Journal of Diabetes Research, 2015, (654204), 2015 PUBLISHED
Journal Article Reilly H, Egaña M and Green S, Intensity-dependent effect of ageing on fatigue during intermittent contractions of the human calf muscle in males and females, European Journal of Applied Physiology, 115, (9), 2015, p1927 - 1937 PUBLISHED
Journal Article Rutkowska, A. Preuss, I. Gessier, F. Sailer, A.W. Dev, K.K., EBI2 regulates intracellular signaling and migration in human astrocyte, Glia, 63, (2), 2015, p341 - 351 PUBLISHED
Journal Article Prenderville JA, Kelly ÁM, Downer EJ, The role of cannabinoids in adult neurogenesis., British journal of pharmacology, 2015 PUBLISHED
Journal Article McManus R.M, Mills K.H.G, Lynch M.A, T Cells-Protective or Pathogenic in Alzheimer-s Disease?, Journal of Neuroimmune Pharmacology, 10, (4), 2015, p547–560 PUBLISHED
Journal Article Barrett J., Costello D., O'Sullivan J., Cowley T., Lynch M., Bone marrow-derived macrophages from aged rats are more responsive to inflammatory stimuli, Journal of Neuroinflammation, 12, (1), 2015, p67 PUBLISHED
Journal Article Barrett J., Minogue A., Falvey A., Lynch M., Involvement of IGF-1 and Akt in M1/M2 activation state in bone marrow-derived macrophages, Experimental Cell Research, 335, (2), 2015, p258–268 PUBLISHED
Journal Article Raasay S. Jones, Aedín M. Minogue, Orla Fitzpatrick, Marina A. Lynch, Inhibition of JAK2 attenuates the increase in inflammatory markers in microglia from APP/PS1 mice, Experimental Cell Research, 36, (10), 2015, p2716–2724 In_Press
Journal Article Ulrich D, Amyloid-ß impairs synaptic inhibition via GABAA receptor endocytosis, Journal of Neuroscience, 35, (24), 2015, p9205 - 9210 PUBLISHED
Journal Article Kiely C, Rocha J, O'Connor E, O'Shea D, Green S and Egaña M, Influence of menopause and type 2 diabetes on pulmonary oxygen uptake kinetics and peak exercise performance during cycling, American Journal of Physiology - Regulatory Integrative and Comparative Physiology , 309, (8), 2015, pR875 - 883 PUBLISHED
Journal Article Chang L, Cui W, Yang Y, Xu S, Zhou W, Fu H, Hu S, Mak S, Hu J, Wang Q, Pui-Yan Ma V, Chung-Lit Choi T, Dik-Lung Ma E, Tao L, Pang Y, Rowan M.J, Anwyl R, Han Y, Wang Q, Protection against ß-amyloid-induced synaptic and memory impairments via altering ß-amyloid assembly by bis(heptyl)-cognitin, Scientific Reports, 5, 2015, p10256- PUBLISHED
Journal Article Fallarino, F., Gargaro, M., Mondanell, G., Downer, E.J., Hossain, M.J. and Gran, B, Delineating the Role of Toll-Like Receptors in the Neuro-inflammation Model EAE., Methods Molecular Biology, (in press), 2015 In_Press
Journal Article Collins, L.M., Downer, E.J., Toulouse, A. and Nolan, Y.M. , Mitogen-Activated Protein Kinase Phosphatase (MKP)-1 in Nervous System Development and Disease. , Molecular Neurobiology. 51(3):1158-67., 2015 PUBLISHED
Journal Article Lynch, MA, Linking T cells to Alzheimer's disease: from neurodegeneration to neurorepair, Current Opinion in Pharmacology, 26, 2015, p67 - 73 PUBLISHED
Journal Article Crowley T, Fitzpatrick JM, Kuijper T, Cryan JF, O'Toole O, O'Leary OF, Downer EJ, Modulation of TLR3/TLR4 inflammatory signaling by the GABAB receptor agonist baclofen in glia and immune cells: relevance to therapeutic effects in multiple sclerosis., Frontiers in cellular neuroscience, 9, 2015, p284 PUBLISHED
Journal Article Nistor Paul A., May Paul W., Tamagnini Francesco, Randall Andrew D., Caldwell Maeve A., Long-term culture of pluripotent stem-cell-derived human neurons on diamonds" A substrate for neurodegeneration research and therapy , Biomaterials , 61 , ( ), 2015, p139 - 149 PUBLISHED
Journal Article Costello D.A, Carney D.G, Lynch M.A, α-TLR2 antibody attenuates the Aβ-mediated inflammatory response in microglia through enhanced expression of SIGIRR, Brain, Behavior, and Immunity, 46, 2015, p70 - 79 PUBLISHED
Journal Article Raasay S. Jones and Marina A. Lynch, How dependent is synaptic plasticity on microglial phenotype?, Neuropharmacology, 96, (A), 2015, p3–10 ACCEPTED
Journal Article Marina A Lynch, Neuroinflammatory changes negatively impact on LTP: a focus on IL-1β, Brain Research, 2015 PUBLISHED
Review Karen Bryson and Marina Lynch, Linking T cells to Alzheimer's disease: from neurodegeneration to neurorepair, Curr Opin Pharmacol. , 26,, 2015, 67-73. PUBLISHED