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James Rooney

Dr. James Rooney graduated from Dublin City University with a first class honours degree in Applied Physics. He later qualified with an honours degree in Medicine from the Royal College of Surgeons in Ireland, and subsequently a Masters in Epidemiology from the London School of Hygiene and Tropical Medicine. He is currently undertaking a PhD in clinical medicine at the Academic Unit of Neurology in Trinity College Dublin. He has been awarded a Health Research Board research training Fellowship to investigate environmental risk factors for ALS.

Current Research

Dr. Rooney’s research encompasses three main areas: the spatial epidemiology of ALS in Ireland; the analysis of clinical, genetic and environmental factors in the survival of ALS patients; and finally he is part of the analysis team for the Euro-MOTOR project. The Euro-MOTOR project is a large international case-control study that aims to identify environmental risk factors for ALS using a systems biology approach.


2017. Neurology. Euro-MOTOR: A case-control study of hormonal exposures as etiological factors for ALS in women. Rooney JPK, Visser AE, D’Ovidio F, Vermoulen R, Beghi E, Chio A, Veldink JH, Logroscino G, Van den Berg L, Hardiman O. Vol: IN PRESS.

2017. J Neurol Neurosurg Psychiatry. C9orf72 expansion differentially affects males with spinal onset amyotrophic lateral sclerosis. Rooney J, Fogh I, Westeneng HJ, Vajda A, McLaughlin R, Heverin M, Jones A, van Eijk R, Calvo A, Mazzini L, Shaw C, Morrison K, Shaw PJ, Robberecht W, Van Damme P, Al-Chalabi A, van den Berg L, Chiò A, Veldink A, Hardiman O. Vol: 88; 4; 281-281.

2017. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. Identifying behavioural changes in ALS: Validation of the Beaumont Behavioural Inventory (BBI). Elamin, Marwa; Pinto-Grau, Marta; Burke, Tom; Bede, Peter; Rooney, James; O’Sullivan, Meabhdh; Lonergan, Katie; Kirby, Emma; Quinlan, Emma; Breen, Nadia. Vol: 18; 42767; 68-73.

2017. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. Critical issues in ALS case-control studies: The case of the Euro-MOTOR study. D’Ovidio, Fabrizio; Rooney, James PK; Visser, Anne E; Vermeulen, Roel CH; Veldink, Jan H; Van Den Berg, Leonard H; Hardiman, Orla; Logroscino, Giancarlo; Chiò, Adriano; Beghi, Ettore; . Vol: ; ; 42948.

2017. J Neurol Neurosurg Psychiatry. The changing picture of amyotrophic lateral sclerosis: lessons from European registers. Hardiman, Orla; Al Chalabi, Ammar; Brayne, Carol; Beghi, Ettore; van den Berg, Leonard H; Chio, Adriano; Martin, Sarah; Logroscino, Giancarlo; Rooney, James. Vol: jnnp-2016-314495.

2017. Neurology. Benefits, pitfalls, and future design of population-based registers in neurodegenerative disease. Rooney, James PK; Brayne, Carol; Tobin, Katy; Logroscino, Giancarlo; Glymour, M Maria; Hardiman, Orla; . Vol: 88; 24; 2321-2329.