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Professor Conleth Feighery
Fellow Emeritus, Fellows Emeritii

Publications and Further Research Outputs

Peer-Reviewed Publications

Hogan PC, O'Connell RM, Scollard S, Browne E, Hackett EE, Feighery C, Biomarkers Predict Relapse in Granulomatosis with Polyangiitis., Journal of biomarkers, 2014, 2014, p596503 Journal Article, 2014 TARA - Full Text DOI

Cooper,Suzanne E J S.E.J., Kennedy,Nicholas P. N.P., Mohamed,Bashir Mustafa B.M., Abuzakouk,Mohamed M., Dunne,Jean J., Byrne,Greg G., McDonald,George S A G.S.A., Davies,Anthony Mitchell A.M., Edwards,Connla C., Kelly,Jacinta D. J.D., Feighery,Conleth F. C.F., Immunological indicators of coeliac disease activity are not altered by long-term oats challenge, Clinical and Experimental Immunology, 171, (3), 2013, p313-318 Journal Article, 2013 DOI TARA - Full Text

O'Reilly V, Zeng SG, Bricard G, Atzberger A, Hogan AE, Jackson J, Feighery C, Porcelli SA, Doherty DG, Distinct and Overlapping Effector Functions of Expanded Human CD4, CD8α and CD4CD8α Invariant Natural Killer T Cells, PloS one, 6, (12, e28648), 2011 Journal Article, 2011 TARA - Full Text DOI

Brophy K*, Ryan AW*, Turner G, Trimble V, Patel KD, O'Morain C, Kennedy NP, Egan B, Close E, Lawlor G, MacMathuna P, Stevens FM, Abuzakouk M, Feighery C, Kelleher D, McManus R, Evaluation of 6 candidate genes on chromosome 11q23 for coeliac disease susceptibility: a case control study, BMC Medical Genetics, 11, (76), 2010 Journal Article, 2010 URL TARA - Full Text

Feighery CF, McManus R., Symposium on 'The challenge of translating nutrition research into public health nutrition'. Session 3: Joint Nutrition Society and Irish Nutrition and Dietetic Institute Symposium on 'Nutrition and autoimmune disease'. Recent advances in genetic understanding of coeliac disease. , Proceedings of the Nutrition Society, 68, (2), 2009, p122-126 Journal Article, 2009 TARA - Full Text

Bracken S, Bryne G, Kelly J, Jackson J, Feighery C , Altered gene expression in highly purified enterocytes from patients with active coeliac disease , BMC Genomics, 8, (9), 2008, p377- Journal Article, 2008

Mohamed BM, Feighery C, Coates C, O'Shea U, Delaney D, O'Briain S, Kelly J, Abuzakouk M. , The absence of a mucosal lesion on standard histological examination does not exclude diagnosis of celiac disease , Digestive Disease Science , 52, (1), 2008, p52 - 61 Journal Article, 2008

Oral Surg Oral Med Oral Pathol Oral Radiol Endo, 103, 5, (2007), 29 - 32p, Healy C, Abuzakouk M, Feighery C, Flint S, [eds.] Journal, 2007

Doyle SL, Jefferies CA, Feighery C, O'Neill LA , Signaling by Toll-like receptors 8 and 9 requires Bruton's tyrosne kinase , Journal of Biological Chemistry, 282, (51), 2007, p36953 - 36960 Journal Article, 2007

Doyle SL, Jefferies CA, Feighery C, O'Neill LA., Signaling by Toll-like receptors 8 and 9 requires Bruton's tyrosine kinase., Journal of Biological Chemistry, 282, (51), 2007, p36953-36960. Journal Article, 2007 TARA - Full Text DOI

Feighery LM, Smith P, O'Mahony L, Fallon PG, Brayden DJ., Effects of Lactobacillus salivarius 433118 on intestinal inflammation, immunity status and in vitro colon function in two mouse models of inflammatory bowel disease., Digestive Diseases and Sciences, 53, (9), 2007, p2495 - 2506 Journal Article, 2007 DOI

Williams Y, Byrne G, Lynch S, Feighery C, Abuzakouk M, Type II Hereditary Angioedema-Presenting as Food Allergy , Digestive Disease Science, 52, (2), 2007, p353 - 356 Journal Article, 2007

van Heel DA, Franke L, Hunt KA, Gwilliam R, Zhernakova A, Inouye M, Wapenaar MC, Barnardo MC, Bethel G, Holmes G, FEIGHERY C, et al. , A genome-wide association study of celiac disease identifies risk variants in the region harboring IL2 and IL21 , Nature Genetics , 39, (7), 2007, p827 - 829 Journal Article, 2007

Healy C, Abuzakouk M, Feighery C, Flint S, Acquired angioedema in non-Hodgkin's lymphoma, Oral Surgical Oral Medicine Oral Pathology Oral Radiol Endod, 103, 2007, p29 - 32 Journal Article, 2007

Abuzakouk M, Barnes L, O'Gorman N, O'Grady A, Mohamed B, McKenna MJ, Freaney R, Feighery C, Dermatitis Herpetiformis: No Evidence of Bone Disease Despite Evidence of Enteropathy, Digestive Disease Science, 52, (3), 2007, p659 - 664 Journal Article, 2007

van Heel DA, Franke L, Hunt KA, Gwilliam R, Zhernakova A, Inouye M, Wapenaar MC, Barnardo MC, Bethel G, Holmes GK, Feighery C, Jewell D, Kelleher D, Kumar P, Travis S, Walters JR, Sanders DS, Howdle P, Swift J, Playford RJ, McLaren WM, Mearin ML, Mulder CJ, McManus R, McGinnis R, Cardon LR, , A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21., Nature Genetics, 39, (7), 2007, p827 - 829 Journal Article, 2007 DOI TARA - Full Text

Lin F, Murphy R, White B, Kelly J, Feighery C, Doyle R, Pittock S, Moroney J, Smith O, Livingstone W, Keenan C, Jackson J, Circulating levels of beta2-glycoprotein I in thrombotic disorders and in inflammation, LUPUS, 15, (2), 2006, p87 - 93 Journal Article, 2006

Byrne G, Ryan F, Jackson J, Feighery C, Kelly J, Mutagenesis of the catalytic triad of tissue transglutaminase abrogates coeliac disease serum IgA autoantibody binding, GUT , 53, 2006, p336 - 341 Journal Article, 2006

Srinivasan U, Jones E, Carolan J, Feighery C, Immunohistochemical analysis of coeliac mucosa following ingestion of oats, Clinical Experimental Immunology , 144, (2), 2006, p197 - 203 Journal Article, 2006

Brophy K, Ryan AW, Thornton JM, Abuzakouk M, Fitzgerald AP, McLoughlin RM, O'Morain C, Kennedy NP, Stevens FM, Feighery C, Kelleher D, McManus R., Haplotypes in the CTLA4 region are associated with coeliac disease in the Irish population, Genes Immunol, 7, (1), 2006, p19 - 26 Journal Article, 2006

Eidenschenk C, Dunne J, Jouanguy E, Fourlinnie C, Gineau L, Bacq D, McMahon C, Smith O, Casanova JL, Abel L, Feighery C, A novel primary immunodeficiency with specific natural-killer cell deficiency maps to the centromeric region of chromosome 8, American Journal Human Genet, 78, (4), 2006, p721 - 727 Journal Article, 2006

Mohamed BM, Feighery C, Kelly J, Coates C, O'Shea U, Barnes L, Abuzakouk M, Increased protein expression of matrix metalloproteinases -1, -3, and -9 and TIMP-1 in patients with gluten-sensitive enteropathy, Digestive Disease Science , 51, (10), 2006, p1862 - 1868 Journal Article, 2006

Kilmartin C, Wieser H, Abuzakouk M, Kelly J, Jackson J, Feighery C, Intestinal T cell responses to cereal proteins in celiac disease, Digestive Disease Science , 51, (1), 2006, p202 - 209 Journal Article, 2006

Daly A, Walsh C, Feighery C, O'Shea U, Jackson J, Whelan A, Serum levels of soluble CD163 correlate with the inflammatory process in coeliac disease, Aliment Pharmacol Ther , 24, (3), 2006, p553 - 559 Journal Article, 2006

Bracken SC, Kilmartin C, Wieser H, Jackson J, Feighery C, Barley and rye prolamins induce an mRNA interferon-gamma response in coeliac mucosa, Aliment Pharmacol Ther , 23, (9), 2006, p1307 - 1314 Journal Article, 2006

Daly A, Walsh C, Feighery C, O'Shea U, Jackson J, Whelan A, Serum levels of soluble CD163 correlate with the inflammatory process in coeliac disease, Aliment Pharmacol Ther , 24, (3), 2006, p553 - 559 Journal Article, 2006

Brophy K, Ryan AW, Thornton JM, Daly JS, McLoughlin R, O' Morain C, Abuzakouk M, Kennedy NP, Stevens FM, Feighery C, Kelleher D, McManus R, Haplotypes in the CTLA4 region are associated with coeliac disease in the Irish population., Genes and Immunity, 7, (1), 2006, p19 - 26 Journal Article, 2006 DOI

Feighery C, Conlon N, Jackson J, Adult population screening for coeliac disease: comparison of tissue-transglutaminase antibody and anti-endomysial antibody tests, European Journal of Gastroenterology & Hepatology , 18, (11), 2006, p1173 - 1175 Journal Article, 2006

Ryan AW, Thornton JM, Brophy K, Daly JS, McLoughlin RM, O'Morain C, Abuzakouk M, Kennedy NP, Stevens FM, Feighery C, Kelleher D, McManus R, Chromosome 5q candidate genes in coeliac disease: genetic variation at IL4, IL5, IL9, IL13, IL17B and NR3C1, Tissue Antigens, 65, (2), 2005, p150 - 155 Journal Article, 2005

Ryan AW, Thornton JM, Brophy K, Daly JS, McLoughlin RM, O'Morain C, Abuzakouk M, Kennedy NP, Stevens FM, Feighery C, Kelleher D, McManus R, Chromosome 5q candidate genes in coeliac disease: genetic variation at IL4, IL5, IL9, IL13, IL17B and NR3C1, Tissue Antigens, 65, (2), 2005, p150 - 155 Journal Article, 2005

Ryan AW, Thornton JM, Brophy K, Daly JS, McLoughlin RM, O' Morain C, Abuzakouk M, Kennedy NP, Stevens FM, Feighery C, Kelleher D, McManus R., Chromosome 5q candidate genes in coeliac disease: genetic variation at IL4, IL5, IL9, IL13, IL17B and NR3C1., Tissue Antigens, 65, (2), 2005, p150 - 155 Journal Article, 2005 DOI

Abuzakouk M, Feighery C, Primary immunodeficiency disorders in the Republic of Ireland: first report of the national registry in children and adults, Journal of Clinical Immunology , 25, (1), 2005, p73 - 77 Journal Article, 2005

De Groot K, Rasmussen N, Bacon PA, Tervaert JW, Feighery C, Gregorini G, Gross WL, Luqmani R, Jayne DR, Randomized trial of cyclophosphamide versus methotrexate for induction of remission in early systemic antineutrophil cytoplasmic antibody-associated vasculitis, Arthritis Rheumatology , 52, (8), 2005, p2461 - 2469 Journal Article, 2005

Ryan AW, Thornton JM, Brophy K, Daly JS, O' Morain C, McLoughlin RM, Kennedy NP, Abuzakouk M, Stevens FM, Feighery C, Kelleher D, McManus R. , Haplotype variation at the IBD5 locus (5q31) in coeliac disease in the Irish population. , Tissue Antigens, 64, (2), 2004, p195 - 198 Journal Article, 2004 DOI

A. W. Ryan, J. M. Thornton, K. Brophy, J. S. Daly, C. O'Morain, R. M. McLoughlin, N. P. Kennedy, M. Abuzakouk, F. M. Stevens, C. Feighery, D. Kelleher and R. McManus, Haplotype variation at the IBD5/SLC22A4 locus (5q31) in coeliac disease in the Irish population, Tissue antigens, 64, (2), 2004, p195-8 Journal Article, 2004 URL

F. Lin, C. Feighery, J. Guerin, H. O'Byrne and J. Jackson, Enzyme-linked immunosorbent assay for beta2-glycoprotein I quantitation: the importance of variability in the plastic support, British journal of biomedical science, 60, (3), 2003, p165-8 Journal Article, 2003 URL

Williams Y, Feighery C, Abuzakouk M, C1q autoantibodies: cause or effect of recurrent infection, LUPUS, 12, 2003, p795 - 797 Journal Article, 2003

Feighery L, Collins C, Feighery C, Mahmud N, Coughlan G, Willoughby R, Jackson J, Anti-transglutaminase antibodies and the serological diagnosis of coeliac disease, British Journal of Biomedical Science, 60, 2003, p14 - 18 Journal Article, 2003

Feighery C, O'Keefe J, TNF-alpha production by intraepithelial T cells in celiac disease, Gastroenterology, 125, 2003, p1560 - 1561 Journal Article, 2003

B. Byrne, L. Madrigal-Estebas, A. McEvoy, J. Carton, D. G. Doherty, A. Whelan, C. Feighery, D. P. O'Donoghue and C. O'Farrelly, Human duodenal epithelial cells constitutively express molecular components of antigen presentation but not costimulatory molecules, Human immunology, 63, (11), 2002, p977-86 Journal Article, 2002 URL

Abuzakouk M, Feighery C, Jackson J, Tumour necrosis factor blocking agents: a new therapeutic modality for inflammatory disorders, British Journal of Biomedical Science , 59, 2002, p173 - 179 Journal Article, 2002

L. Madrigal-Estebas, D. G. Doherty, D. P. O'Donoghue, C. Feighery and C. O'Farrelly, Differential expression and upregulation of interleukin-1alpha, interleukin-1beta and interleukin-6 by freshly isolated human small intestinal epithelial cells, Mediators of inflammation, 11, (5), 2002, p313-9 Journal Article, 2002 URL

Aganna E, Martinon F, Hawkins PN, Ross JB, Swan DC, Booth DR, Lachmann HJ, Bybee A, Gaudet R, Woo P, Feighery C, Cotter FE, Thome M, Hitman GA, Tschopp J, McDermott MF, Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosis, Arthritis Rheumatology , 46, 2002, p2445 - 2452 Journal Article, 2002

O'Leary C, Feighery C, Feighery A, Quane K, Shanahan F, Molloy M, Cronin CC. , The prevalence of coeliac disease among female subjects having bone densitometry , Irish Journal of Medical Science , 171, (3), 2002, p145 - 147 Journal Article, 2002

J. O'Keeffe, S. Lynch, A. Whelan, J. Jackson, N. P. Kennedy, D. G. Weir and C. Feighery, Flow cytometric measurement of intracellular migration inhibition factor and tumour necrosis factor alpha in the mucosa of patients with coeliac disease, Clinical and experimental immunology, 125, (3), 2001, p376-82 Journal Article, 2001 URL

J. Dunne, S. Lynch, C. O'Farrelly, S. Todryk, J. E. Hegarty, C. Feighery and D. G. Doherty, Selective expansion and partial activation of human NK cells and NK receptor-positive T cells by IL-2 and IL-15, Journal of immunology (Baltimore, Md, 167, (6), 2001, p3129-38 Journal Article, 2001 URL

M. Abuzakouk, C. Feighery, D. Kelleher, D. S. O'Briain, E. Jones, D. Weir, E. Casey and C. O'Farrelly, Increased HLA-DR and CD44 antigen expression in the gut: evidence of extraarticular immunological activity in rheumatoid arthritis, The Journal of rheumatology, 26, (9), 1999, p1869-76 Journal Article, 1999 URL

C. Feighery, D. G. Weir, A. Whelan, R. Willoughby, S. Youngprapakorn, S. Lynch, C. O'Morain, P. McEneany and C. O'Farrelly, Diagnosis of gluten-sensitive enteropathy: is exclusive reliance on histology appropriate?, European journal of gastroenterology & hepatology, 10, (11), 1998, p919-25 Journal Article, 1998 URL

J. Guerin, O. Smith, B. White, G. Sweetman, C. Feighery and J. Jackson, Antibodies to prothrombin in antiphospholipid syndrome and inflammatory disorders, British journal of haematology, 102, (4), 1998, p896-902 Journal Article, 1998 URL

M. Abuzakouk, J. Carton, C. Feighery, D. P. O'Donoghue, D. G. Weir and C. O'Farrelly, CD4+ CD8+ and CD8alpha+ beta- T lymphocytes in human small intestinal lamina propria, European journal of gastroenterology & hepatology, 10, (4), 1998, p325-9 Journal Article, 1998 URL

U. Srinivasan, D. G. Weir, C. Feighery and C. O'Farrelly, Emergence of classic enteropathy after longstanding gluten sensitive oral ulceration, BMJ (Clinical research ed), 316, (7126), 1998, p206-7 Journal Article, 1998 URL

C. Feighery, M. Abuzakouk, C. Liddy, J. Jackson, A. Whelan, R. Willougby, C. Cronin and D. S. Kumararatne, Endomysial antibody detection using human umbilical cord tissue as substrate: reactivity of cells in Wharton's jelly, British journal of biomedical science, 55, (2), 1998, p107-10 Journal Article, 1998 URL

L. Madrigal-Estebas, R. McManus, B. Byrne, S. Lynch, D. G. Doherty, D. Kelleher, D. P. O'Donoghue, C. Feighery and C. O'Farrelly, Human small intestinal epithelial cells secrete interleukin-7 and differentially express two different interleukin-7 mRNA Transcripts: implications for extrathymic T-cell differentiation, Human Immunology, 58, (2), 1997, p83-90 Journal Article, 1997 DOI

C. Feighery, A. Whelan and D. G. Weir, Endomysium: autoantigen in coeliac disease, European journal of gastroenterology & hepatology, 9, (7), 1997, p655-6 Journal Article, 1997 URL

L. Madrigal-Estebas, R. McManus, B. Byrne, S. Lynch, D. G. Doherty, D. Kelleher, D. P. O'Donoghue, C. Feighery and C. O'Farrelly, Human small intestinal epithelial cells secrete interleukin-7 and differentially express two different interleukin-7 mRNA Transcripts: implications for extrathymic T-cell differentiation, Human immunology, 58, (2), 1997, p83-90 Journal Article, 1997 URL

J. V. Reynolds, C. O'Farrelly, C. Feighery, P. Murchan, N. Leonard, G. Fulton, C. O'Morain, F. B. Keane and W. A. Tanner, Impaired gut barrier function in malnourished patients, The British journal of surgery, 83, (9), 1996, p1288-91 Journal Article, 1996 URL

M. Abuzakouk, C. Feighery and C. O'Farrelly, Collagenase and Dispase enzymes disrupt lymphocyte surface molecules, Journal of immunological methods, 194, (2), 1996, p211-6 Journal Article, 1996 URL

U. Srinivasan, N. Leonard, E. Jones, D. D. Kasarda, D. G. Weir, C. O'Farrelly and C. Feighery, Absence of oats toxicity in adult coeliac disease, BMJ (Clinical research ed), 313, (7068), 1996, p1300-1 Journal Article, 1996 URL

J. Hassan, G. Yanni, V. Hegarty, C. Feighery, B. Bresnihan and A. Whelan, Increased numbers of CD5+ B cells and T cell receptor (TCR) gamma delta+ T cells are associated with younger age of onset in rheumatoid arthritis (RA), Clinical and experimental immunology, 103, (3), 1996, p353-6 Journal Article, 1996 URL

M. Abuzakouk, D. Kelleher, C. Feighery and C. O'Farrelly, Increased HLA-DR and decreased CD3 on human intestinal intraepithelial lymphocytes: evidence of activation?, Gut, 39, (3), 1996, p396-400 Journal Article, 1996 TARA - Full Text URL

D. Kelleher, A. Murphy, C. Feighery and E. B. Casey, Leukocyte function-associated antigen 1 (LFA-1) and CD44 are signalling molecules for cytoskeleton-dependent morphological changes in activated T cells, Journal of leukocyte biology, 58, (5), 1995, p539-46 Journal Article, 1995 URL

E. Corrigan, D. Kelleher, C. Feighery and A. Long, Protein kinase C isoform expression in CD45RA+ and CD45RO+ T lymphocytes, Immunology, 85, (2), 1995, p299-303 Journal Article, 1995 TARA - Full Text URL

G. Yanni, A. Whelan, C. Feighery and B. Bresnihan, Synovial tissue macrophages and joint erosion in rheumatoid arthritis, Annals of the rheumatic diseases, 53, (1), 1994, p39-44 Journal Article, 1994 URL

J. Hassan, C. Feighery, B. Bresnihan, M. Keogan, M. X. Fitzgerald and A. Whelan, Serum IgA and IgG subclasses during treatment for acute respiratory exacerbation in cystic fibrosis: analysis of patients colonised with mucoid or non-mucoid strains of pseudomonas aeruginosa, Immunological investigations, 23, (1), 1994, pJan-13 Journal Article, 1994 URL

L. Madrigal, S. Lynch, C. Feighery, D. Weir, D. Kelleher and C. O'Farrelly, Flow cytometric analysis of surface major histocompatibility complex class II expression on human epithelial cells prepared from small intestinal biopsies, Journal of immunological methods, 158, (2), 1993, p207-14 Journal Article, 1993 URL

M. T. Keogan, M. Callaghan, G. Yanni, D. Mulherin, C. Feighery, D. L. Brown, M. X. Fitzgerald and B. Bresnihan, Spontaneous in vitro production of rheumatoid factor during infectious exacerbations of cystic fibrosis: correlation with circulating immune complex levels, Clinical and experimental immunology, 91, (3), 1993, p462-6 Journal Article, 1993 URL

G. Yanni, A. Whelan, C. Feighery, O. Fitzgerald and B. Bresnihan, Morphometric analysis of synovial membrane blood vessels in rheumatoid arthritis: associations with the immunohistologic features, synovial fluid cytokine levels and the clinical course, The Journal of rheumatology, 20, (4), 1993, p634-8 Journal Article, 1993 URL

A. Murphy, K. C. Breen, A. Long, C. Feighery, E. B. Casey and D. Kelleher, Neurofilament expression in human T lymphocytes, Immunology, 79, (1), 1993, p167-70 Journal Article, 1993 URL

G. Yanni, A. Whelan, C. Feighery, W. Quinlan, J. Symons, G. Duff and B. Bresnihan, Contrasting levels of in vitro cytokine production by rheumatoid synovial tissues demonstrating different patterns of mononuclear cell infiltration, Clinical and experimental immunology, 93, (3), 1993, p387-95 Journal Article, 1993 URL

A. Murphy, K. C. Breen, A. Long, C. Feighery, E. B. Casey and D. Kelleher, Neurofilament expression in human T lymphocytes, Immunology, 79, (1), 1993, p167-170 Journal Article, 1993 TARA - Full Text

M. Callaghan, A. Whelan, C. Feighery and B. Bresnihan, IL-2 enhances polyclonal IgM but not IgM-rheumatoid factor synthesis by activated human peripheral blood B cells, Clinical and experimental immunology, 93, (2), 1993, p212-7 Journal Article, 1993 URL

G. Yanni, A. Whelan, C. Feighery and B. Bresnihan, Analysis of cell populations in rheumatoid arthritis synovial tissues, Seminars in arthritis and rheumatism, 21, (6), 1992, p393-9 Journal Article, 1992 URL

J. Hassan, C. Feighery, B. Bresnihan and A. Whelan, Prevalence of anti-Fab antibodies in patients with autoimmune and infectious diseases, Clinical and experimental immunology, 89, (3), 1992, p423-6 Journal Article, 1992 URL

M. Soden, M. Rooney, A. Whelan, C. Feighery and B. Bresnihan, Immunohistological analysis of the synovial membrane: search for predictors of the clinical course in rheumatoid arthritis, Annals of the rheumatic diseases, 50, (10), 1991, p673-6 Journal Article, 1991 URL

J. Hassan, A. Whelan, B. Bresnihan and C. Feighery, Induction of IgM and IgM-rheumatoid factor synthesis in vitro by indomethacin, Rheumatology international, 10, (6), 1991, p235-9 Journal Article, 1991 URL

J. Hassan, C. Feighery, B. Bresnihan and A. Whelan, Effect of gold therapy on CD5+ B-cells and TCR gamma delta+ T-cells in patients with rheumatoid arthritis, Rheumatology international, 11, (04-May), 1991, p175-8 Journal Article, 1991 URL

D. G. Quinn, J. S. Fennell, O. Sheils, E. F. Gaffney and C. F. Feighery, Effect of cyclosporin on immune complex deposition in murine glomerulonephritis, Immunology, 72, (4), 1991, p550-4 Journal Article, 1991 URL

C. O'Farrelly, C. O'Mahony, F. Graeme-Cook, C. Feighery, B. E. McCartan and D. G. Weir, Gliadin antibodies identify gluten-sensitive oral ulceration in the absence of villous atrophy, Journal of oral pathology & medicine, 20, (10), 1991, p476-8 Journal Article, 1991 URL

J. Hassan, C. Feighery, B. Bresnihan and A. Whelan, Elevated T cell receptor gamma delta + T cells in patients with infectious mononucleosis, British journal of haematology, 77, (2), 1991, p255-6 Journal Article, 1991 URL

M. Soden, A. Whelan, C. Feighery and B. Bresnihan, Lymphocyte infiltration and the synthesis of IgM and IgA rheumatoid factors by rheumatoid synovial membrane, Rheumatology international, 10, (4), 1990, p149-52 Journal Article, 1990 URL

D. Kelleher, C. Feighery and D. G. Weir, Chemiluminescence by polymorphonuclear leucocyte subpopulations in chronic inflammatory bowel disease. Influence of the cell separation procedure, Digestion, 45, (3), 1990, p158-65 Journal Article, 1990 URL

J. Hassan, C. Feighery, B. Bresnihan and A. Whelan, Increased CD5+ B cells in infectious mononucleosis, British journal of haematology, 74, (3), 1990, p375-6 Journal Article, 1990 URL

M. Rooney, A. Whelan, C. Feighery and B. Bresnihan, The immunohistologic features of synovitis, disease activity and in vitro IgM rheumatoid factor synthesis by blood mononuclear cells in rheumatoid arthritis, The Journal of rheumatology, 16, (4), 1989, p459-67 Journal Article, 1989 URL

M. Coffey, J. Hassan, C. Feighery, M. Fitzgerald and B. Bresnihan, Rheumatoid factors in cystic fibrosis: associations with disease manifestations and recurrent bacterial infections, Clinical and experimental immunology, 77, (1), 1989, p52-7 Journal Article, 1989 URL

J. Hassan, C. Feighery, B. Bresnihan and A. Whelan, Expression and regulation of the HLA-DR antigen on circulating monocytes isolated from patients with rheumatoid arthritis, Arthritis and rheumatism, 32, (6), 1989, p682-90 Journal Article, 1989 URL

M. Soden, J. Hassan, D. L. Scott, J. G. Hanly, M. Moriarty, A. Whelan, C. Feighery and B. Bresnihan, Lymphoid irradiation in intractable rheumatoid arthritis. Long-term followup of patients treated with 750 rads or 2,000 rads, Arthritis and rheumatism, 32, (5), 1989, p523-30 Journal Article, 1989 URL

M. Rooney, A. Whelan, C. Feighery and B. Bresnihan, Changes in lymphocyte infiltration of the synovial membrane and the clinical course of rheumatoid arthritis, Arthritis and rheumatism, 32, (4), 1989, p361-9 Journal Article, 1989 URL

M. Soden, M. Rooney, A. Cullen, A. Whelan, C. Feighery and B. Bresnihan, Immunohistological features in the synovium obtained from clinically uninvolved knee joints of patients with rheumatoid arthritis, British journal of rheumatology, 28, (4), 1989, p287-92 Journal Article, 1989 URL

P. A. McCormick, C. Feighery, C. Dolan, C. O'Farrelly, P. Kelliher, F. Graeme-Cook, A. Finch, K. Ward, M. X. Fitzgerald, D. P. O'Donoghue and et al., Altered gastrointestinal immune response in sarcoidosis, Gut, 29, (12), 1988, p1628-31 Journal Article, 1988 URL

M. Rooney, D. Condell, W. Quinlan, L. Daly, A. Whelan, C. Feighery and B. Bresnihan, Analysis of the histologic variation of synovitis in rheumatoid arthritis, Arthritis and rheumatism, 31, (8), 1988, p956-63 Journal Article, 1988 URL

P. Rogers, J. Hassan, B. Bresnihan, C. Feighery and A. Whelan, Antibodies to Proteus in rheumatoid arthritis, British journal of rheumatology, 27 Suppl 2, 1988, p90-4 Journal Article, 1988 URL

C. O'Farrelly, F. Graeme-Cook, D. O. Hourihane, C. Feighery and D. G. Weir, Histological changes associated with wheat protein antibodies in the absence of villous atrophy, Journal of clinical pathology, 40, (10), 1987, p1228-30 Journal Article, 1987 URL

K. Mealy, C. O'Farrelly, R. Stephens and C. Feighery, Impaired neutrophil function during anesthesia and surgery is due to serum factors, The Journal of surgical research, 43, (5), 1987, p393-7 Journal Article, 1987 URL

J. Kelly, C. O'Farrelly, C. O'Mahony, D. G. Weir and C. Feighery, Immunoperoxidase demonstration of the cellular composition of the normal and coeliac small bowel, Clinical and experimental immunology, 68, (1), 1987, p177-88 Journal Article, 1987 URL

J. Hassan, C. Feighery, B. Bresnihan and A. Whelan, Characterization and quantification of solubilised HLA-DR antigens from circulating human monocytes using an immunoblotting procedure, Tissue antigens, 30, (4), 1987, p167-75 Journal Article, 1987 URL

J. Kelly, C. O'Farrelly, J. P. Rees, C. Feighery and D. G. Weir, Humoral response to alpha gliadin as serological screening test for coeliac disease, Archives of disease in childhood, 62, (5), 1987, p469-73 Journal Article, 1987 URL

D. Kelleher, F. J. Bloomfield, T. Lenehan, M. Griffin, C. Feighery, and S. R. McCann, Chronic granulomatous disease presenting as an oculomucocutaneous syndrome mimicking Behçet's syndrome, Postgraduate Medical Journal, 62, (728), 1986, p489 - 491 Journal Article, 1986 TARA - Full Text

J. G. Hanly, J. Hassan, M. Moriarty, C. Barry, J. Molony, E. Casey, A. Whelan, C. Feighery and B. Bresnihan, Lymphoid irradiation in intractable rheumatoid arthritis. A double-blind, randomized study comparing 750-rad treatment with 2,000-rad treatment, Arthritis and rheumatism, 29, (1), 1986, p16-25 Journal Article, 1986 URL

J. G. Hanly, J. Hassan, A. Whelan, C. Feighery and B. Bresnihan, Effects of gold therapy on the synthesis and quantity of serum and synovial fluid IgM, IgG, and IgA rheumatoid factors in rheumatoid arthritis patients, Arthritis and rheumatism, 29, (4), 1986, p480-7 Journal Article, 1986 URL

J. Hassan, J. Hanly, B. Bresnihan, C. Feighery and C. A. Whelan, The immunological consequences of gold therapy: a prospective study in patients with rheumatoid arthritis, Clinical and experimental immunology, 63, (3), 1986, p614-20 Journal Article, 1986 URL

C. O'Farrelly, C. Feighery, D. S. O'Briain, F. Stevens, C. E. Connolly, C. McCarthy and D. G. Weir, Humoral response to wheat protein in patients with coeliac disease and enteropathy associated T cell lymphoma, British medical journal (Clinical research ed), 293, (6552), 1986, p908-10 Journal Article, 1986 URL

J. Kelly, C. O'Farrelly, J. P. Rees, C. F. Feighery and D. G. Weir, Alpha-gliadin antibodies in childhood coeliac disease, Lancet, 2, (8454), 1985, p558-9 Journal Article, 1985 URL

J. G. Hanly, J. Hassan, M. Moriarty, A. Whelan, C. Feighery and B. Bresnihan, Lymphoid irradiation in intractable rheumatoid arthritis: effects on the production of immunoglobulins and rheumatoid factors, Clinical and experimental immunology, 62, (3), 1985, p647-56 Journal Article, 1985 URL

C. O'Farrelly, J. Kelly, C. Feighery, J. P. Rees, H. Monaghan, E. Tempany and D. G. Weir, Coeliac disease, Irish medical journal, 78, (10), 1985, p299 Journal Article, 1985 URL

C. O'Farrelly, U. McKeever, C. Feighery and D. G. Weir, Increased concanavalin A induced suppression in treated and untreated coeliac disease, Gut, 25, (6), 1984, p644-8 Journal Article, 1984 URL

C. O'Farrelly, C. A. Whelan, C. F. Feighery and D. G. Weir, Suppressor-cell activity in coeliac disease induced by alpha-gliadin, a dietary antigen, Lancet, 2, (8415), 1984, p1305-7 Journal Article, 1984 URL

C. O'Farrelly, J. Kelly, W. Hekkens, B. Bradley, A. Thompson, C. Feighery and D. G. Weir, Alpha gliadin antibody levels: a serological test for coeliac disease, British medical journal (Clinical research ed), 286, (6383), 1983, p2007-10 Journal Article, 1983 URL

C. O'Farrelly, W. T. Hekkens, C. Feighery and D. G. Weir, The specificity of wheat protein reactivity in coeliac disease, Scandinavian journal of gastroenterology, 18, (5), 1983, p603-7 Journal Article, 1983 URL

C. O'Farrelly, C. Feighery, J. F. Greally and D. G. Weir, Cellular response to alpha-gliadin in untreated coeliac disease, Gut, 23, (1), 1982, p83-7 Journal Article, 1982 URL

Research Expertise

Description

Since my appointment as Consultant Immunologist to St. James's Hospital and the former Federated Dublin Voluntary Hospitals (now Tallaght or AMNiCH hospital), I developed clinical and research interests in the following areas: . PRIMARY IMMUNODEFICIENCY DISORDERS . AUTOIMMUNE DISORDERS, IN PARTICULAR CONNECTIVE TISSUE DISEASES . WEGENER'S GRANULOMATOSIS . COELIAC DISEASE. Since 1982, a busy clinical and laboratory Immunology service has evolved. The laboratory currently performs investigations on some 80,000 specimens per annum. A busy outpatient and daycare facility was established. In excess of 60 patients with primary immunodeficiency states attend the clinic and a home based therapy has been developed for patients with immunoglobulin deficiency states. Research has focused in particular on auto-immune disorders, with coeliac disease as the principal interest. However, research into other disorders including primary immunodeficiency states also continues.

Recognition

Representations

Copy, Inflammatory Lung Disease, Proposed workshop on inflammatory diseases of the lung.Includes clinicians presenting on their specific disease type to fundamental scientists.Objectives :To build links between fundamental and clinican scientistsTo look for opportunities for trans-institutional collaborationTo connect senior post-docs (emerging PI's) with clinician counterpart