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Professor Veronica O’Keane

  • Position:Senior Lecturer, Department of Pyschiatry , Consultant Psychiatrist AMiNCH Hospital
  • Contact details: Trinity Health Sciences Centre, AMNCH, Tallaght, Dublin 24
  • Email:vokeane@tcd.ie

Research Interests

My research focus is in two parts, firstly to continue research in the theme of antenatal depression and the possible fetal origins of depression. A collaborative inter-disciplinary research group has been set up comprising The Department of Psychiatry in AMNCH (Tallaght) Hospital, the Coombe Women & Infants University Hospital and Trinity College Institute of Neuroscience. Professors Deirdre Murphy, Head of Department of Obstetrics (School of Medicine, TCD) will be the obstetric lead; and Professor Thomas Connor, Associate Professor of Neuroscience (TCIN) will provide the biochemical expertise and laboratory analysis.

The second arm of my research plan involves collaboration with Professor Thomas Frodl, clinical colleagues in AMNCH (Tallaght) Hospital and community psychiatric services to apply brain neuroimaging and neuroendocrine research tools to examine the effects of clinical intervention in populations of patients with affective disorders.

Publications

PubMed indexed publications

Dayan J, Creveuil C, Dreyfus M, Herlicoviez M, Baleyte JM, O'Keane V. Developmental model of depression applied to prenatal depression: role of present and past life events, past emotional disorders and pregnancy stress. PLoS One. 2010, 5(9),e12942.

Bajbouj M, Merkl A, Schlaepfer TE, Frick C, Zobel A, Maier W, O’Keane V, Corcoran C, Heuser I. Two-year outcome of vagus nerve stimulation in treatment-resistant depression. Journal of Clinical Psychopharmacology 2010, 30(3), 273-81.

Schlaepfer TE, Frick C, Zobel A, Maier W, Heuser I, Bajbouj M, O’Keane V, Corcoran C, Adoldsson R, Trimble M, Rau H, Hoff HJ, Padberg F, Muller-Siecheneder F, Audenaert K, Van den Abbeele D, Matthews K, Christmas D, Stanga Z, Hasdeimer M. Vagus nerver stimulation for depression: efficacy and safety in a European study. Psychological Medicine 2008, 38, 651-61.

Pawlby S, Sharp D, Hay D, O’Keane V. Postnatal depression and child outcome at 11 years: the importance of accurate diagnosis. Journal of Affective Disorders 2008, 107, 241-5.

Mir A, Shivakumar K, Willianson RJ, McAllister V, O’Keane V, Aitchison KJ Change in sexual dysfunction with aripiprazole: a switching or add-on study. Journal of Psychopharmacology 2008, 22, 244-53.

 

Research Funding

MRC Brain Sciences award, Principal Investigator.