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Dr Aine Kelly

  • Senior Lecturer in Physiology
  • Contact details: Department of Physiology, Trinity College Dublin.
  • Email:
  • Telephone: 353-01-896-3794

Research Interests

My research interests centre on the roles of the neurotrophic factors in cognitive function, particularly hippocampal-dependent learning. In my laboratory, we use a combination of in vivo and in vitro techniques including animal learning and behaviour, immunocytochemistry and a range of biochemical and moleclar techniques. We are particularly interested in the cellular mechanisms by which interventions such as environmental enrichment and physical exercise can improve cognition in young, healthy laboratory animals and protect against degenerative changes caused by ageing and by experimentally-induced neuronal cell damage.

Selected Publications

Griffin, E. W., Mullally, S., Foley, C., Warmington, S. A., O'Mara, S. M., and Kelly, A. M. (2011) Aerobic exercise improves hippocampal function and increases BDNF in the serum of young adult males, Physiol Behav 104, 934-941.

Hennigan, A., Callaghan, C. K., Kealy, J., Rouine, J., and Kelly, A. M. (2009) Deficits in LTP and recognition memory in the genetically hypertensive rat are associated with decreased expression of neurotrophic factors and their receptors in the dentate gyrus, Behavioural brain research 197, 371-377.

O'Callaghan, R. M., Griffin, E. W., and Kelly, A. M. (2009) Long-term treadmill exposure protects against age-related neurodegenerative change in the rat hippocampus, Hippocampus.

Griffin, E. W., Bechara, R. G., Birch, A. M., and Kelly, A. M. (2009) Exercise enhances hippocampal-dependent learning in the rat: Evidence for a BDNF-related mechanism, Hippocampus.

All publications

Research Funding

Science Foundation Ireland, Health Research Board, Irish Research Council for Science, Engineering and Technology