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Recent Publications

Olatunji S, Yu X, Bailey J, Huang C, Zapotoczna M, Bowen K, Remškar M, Müller R, Scanlan EM, Geoghegan JA, Olieric V, Caffrey M (2020) Structures of lipoprotein signal peptidase II from Staphylococcus aureus complexed with antibiotics globomycin and myxovirescin. Nature Communications. 11(1):140.

Pickering AC, Vitry P, Prystopiuk V, Garcia B, Höök M, Schoenebeck J, Geoghegan JA, Dufrêne YF, Fitzgerald JR. (2019) Host-specialized fibrinogen-binding by a bacterial surface protein promotes biofilm formation and innate immune evasion. PLoS Pathogens. 15(6):e1007816.

Lacey KA, Mulcahy ME, Towell AM, Geoghegan JA, McLoughlin RM (2019). Clumping factor B is an important virulence factor during Staphylococcus aureus skin infection and a promising vaccine target. PLoS Pathogens. 15(4):e1007713.

Zapotoczna M, Riboldi GP, Moustafa AM, Dickson E, Narechania A, Morrissey JA, Planet PJ, Holden MTG, Waldron KJ,  Geoghegan JA (2018) Mobile-Genetic-Element-Encoded Hypertolerance to Copper Protects   Staphylococcus aureus  from Killing by Host Phagocytes.   mBio. 9(5). pii: e00550-18.   doi: 10.1128/mBio.00550-18.

Herman-Bausier P, Labate C, Towell AM, Derclaye S, Geoghegan JA, Dufrêne YF (2018)   Staphylococcus aureus  clumping factor A is a force-sensitive molecular switch that activates bacterial adhesion.   Proceedings of the National Academy of Sciences USA.   115(21):5564-5569   .

Harkins CP, McAleer MA, Bennett D, McHugh M, Fleury OM, Pettigrew KA, Oravcová K, Parkhill J, Proby CM, Dawe RS,  Geoghegan JA, Irvine AD , Holden MTG (2018) The widespread use of topical antimicrobials enriches for resistance in   Staphylococcus aureus  isolated from patients with atopic dermatitis. Br J Dermatol. 179(4):951-958.   doi: 10.1111/bjd.16722  .

Fleury OM, McAleer MA, Feuillie C, Formosa-Dague C, Sansevere E, Bennett DE, Towell AM, McLean WHI, Kezic S, Robinson DA, Fallon PG, Foster TJ, Dufrêne YF, Irvine AD, Geoghegan JA (2017) Clumping factor B promotes adherence of   Staphylococcus aureus  to corneocytes in atopic dermatitis.   Infection and immunity. 85(6).    doi: 10.1128/IAI.00994-16  .   Read more about this paper.

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