Functional Genomics of Pathogenic Bacteria
Our research focusses on virulence gene regulation, antibiotic resistance and RNA biology of Gram-negative bacterial pathogens using Salmonella enterica and Acinetobacter baumannii as model organisms. To adapt and respond to changing conditions during infection and in the environment, bacteria possess the remarkable ability to modulate their gene expression programs quickly and efficiently.
Leader of the Functional Genomics of Pathogenic Bacteria research group To adapt and respond to changing conditions during infection and in the environment, bacteria possess the remarkable ability to modulate their gene expression programs quickly and efficiently. We use whole genome (Next-Generation Sequencing, RNA-seq) and gene specific methods to study transcriptional networks, mechanisms and antibiotic resistance of Gram-negative pathogens and their regulation (by small RNAs and protein transcription factors) to understand how bacterial pathogens sense, respond and survive during environmental changes.
Principal Investigator Profile
Assistant Professor Carsten Kröger