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Introduction to Nuclear and Toxic Elements Chemistry

Prof. Yurii Gun'ko

 

• Introduction to Nuclear Chemistry: the different kinds of nuclear decay, kinetics, mass loss and energy, half-life, effects of nuclear radiation on matter
• Applications of radioisotopes: radio-carbon dating, nuclear metals in medicine (diagnostics and radiation therapy)
• Introduction to toxicity, HSAB principles and chelation therapy
•  Toxic elements: general features, bioavailability,  biomethylation
• Be, Al, Tl, Hg, Pb and Cd toxicity: sources, symptoms, mechanisms, treatment
• Nanotoxicology
• Therapeutic use of a toxic element: cisplatin for cancer treatment (DNA adducts, side effects, resistance), other metal based anti-cancer drugs