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Publications

Below is the list of peer and non peer publications from the School of Biochemistry and Immunology.

Show: AllPeer ReviewedNon Peer Reviewed
28 publications from 2022

McDonald AG, Mariethoz J, Davey GP, Lisacek F., In silico analysis of the human milk oligosaccharide glycome reveals key enzymes of their biosynthesis., Scientific Reports, 27, (12(1)), 2022, p10846-
Journal Article; Published; Peer Reviewed; Author Profile: GDAVEY; DOI

Hooftman, A. and O'Neill, L.A.J., Nanoparticle asymmetry shapes an immune response, Nature, 601, (7893), 2022, p323-325
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Baldanti, F. and Ganguly, N.K. and Wang, G. and Möckel, M. and O†Neill, L.A. and Renz, H. and dos Santos Ferreira, C.E. and Tateda, K. and Van Der Pol, B., Choice of SARS-CoV-2 diagnostic test: challenges and key considerations for the future, Critical Reviews in Clinical Laboratory Sciences, 2022
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Toller-Kawahisa, J.E. and O†Neill, L.A.J., Creating ATP via creatine kinase B for NLRP3 activation, Nature Immunology, 2022
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Peace, C.G. and O†Neill, L.A.J., The role of itaconate in host defense and inflammation, Journal of Clinical Investigation, 132, (2), 2022
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Ryan, D.G. and Knatko, E.V. and Casey, A.M. and Hukelmann, J.L. and Dayalan Naidu, S. and Brenes, A.J. and Ekkunagul, T. and Baker, C. and Higgins, M. and Tronci, L. and Nikitopolou, E. and Honda, T. and Hartley, R.C. and O'Neill, L.A.J. and Frezza, C. and Lamond, A.I. and Abramov, A.Y. and Arthur, J.S.C. and Cantrell, D.A. and Murphy, M.P. and Dinkova-Kostova, A.T., Nrf2 activation reprograms macrophage intermediary metabolism and suppresses the type I interferon response, iScience, 25, (2), 2022
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Runtsch, M.C. and Angiari, S. and Hooftman, A. and Wadhwa, R. and Zhang, Y. and Zheng, Y. and Spina, J.S. and Ruzek, M.C. and Argiriadi, M.A. and McGettrick, A.F. and Mendez, R.S. and Zotta, A. and Peace, C.G. and Walsh, A. and Chirillo, R. and Hams, E. and Fallon, P.G. and Jayamaran, R. and Dua, K. and Brown, A.C. and Kim, R.Y. and Horvat, J.C. and Hansbro, P.M. and Wang, C. and O'Neill, L.A.J., Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages, Cell Metabolism, 34, (3), 2022, p487-501.e8
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Ryan, T.A.J. and Preston, R.J.S. and O†Neill, L.A.J., Immunothrombosis and the molecular control of tissue factor by pyroptosis: prospects for new anticoagulants, Biochemical Journal, 479, (6), 2022, p731-750
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Pinkerton, J.W. and Kim, R.Y. and Brown, A.C. and Rae, B.E. and Donovan, C. and Mayall, J.R. and Carroll, O.R. and Khadem Ali, M. and Scott, H.A. and Berthon, B.S. and Baines, K.J. and Starkey, M.R. and Kermani, N.Z. and Guo, Y.-K. and Robertson, A.A.B. and O'Neill, L.A.J. and Adcock, I.M. and Cooper, M.A. and Gibson, P.G. and Wood, L.G. and Hansbro, P.M. and Horvat, J.C., Relationship between type 2 cytokine and inflammasome responses in obesity-associated asthma, Journal of Allergy and Clinical Immunology, 149, (4), 2022, p1270-1280
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Campiani, G. and Khan, T. and Ulivieri, C. and Staiano, L. and Papulino, C. and Magnano, S. and Nathwani, S. and Ramunno, A. and Lucena-Agell, D. and Relitti, N. and Federico, S. and Pozzetti, L. and Carullo, G. and Casagni, A. and Brogi, S. and Vanni, F. and Galatello, P. and Ghanim, M. and McCabe, N. and Lamponi, S. and Valoti, M. and Ibrahim, O. and O'Sullivan, J. and Turkington, R. and Kelly, V.P. and VanWemmel, R. and Díaz, J.F. and Gemma, S. and Zisterer, D. and Altucci, L. and De Matteis, A. and Butini, S. and Benedetti, R., Design and synthesis of multifunctional microtubule targeting agents endowed with dual pro-apoptotic and anti-autophagic efficacy, European Journal of Medicinal Chemistry, 235, (114274), 2022
Journal Article; Published; Peer Reviewed; Author Profile: DZISTRER; DOI; URL

Williams, N.C. and Ryan, D.G. and Costa, A.S.H. and Mills, E.L. and Jedrychowski, M.P. and Cloonan, S.M. and Frezza, C. and O'Neill, L.A., Signaling metabolite L-2-hydroxyglutarate activates the transcription factor HIF-1α in lipopolysaccharide-activated macrophages, Journal of Biological Chemistry, 298, (2), 2022
Journal Article; Published; Peer Reviewed; Author Profiles: LAONEILL NULL-25DD5D6F8D3B8B68 ; DOI; URL

Gibbons, L. and Ozaki, E. and Greene, C. and Trappe, A. and Carty, M. and Coppinger, J.A. and Bowie, A.G. and Campbell, M. and Doyle, S.L., SARM1 Promotes Photoreceptor Degeneration in an Oxidative Stress Model of Retinal Degeneration, Frontiers in Neuroscience, 16, (852114), 2022
Journal Article; Published; Peer Reviewed; Author Profiles: AGBOWIE DOYLES8 ; DOI; URL

Wahaab, A. and Mustafa, B.E. and Hameed, M. and Stevenson, N.J. and Anwar, M.N. and Liu, K. and Wei, J. and Qiu, Y. and Ma, Z., Potential role of flavivirus ns2b-ns3 proteases in viral pathogenesis and anti-flavivirus drug discovery employing animal cells and models: A review, Viruses, 14, (1), 2022
Journal Article; Published; Peer Reviewed; Author Profile: STEVENNJ; DOI; URL

Zhang, Y. and Gargan, S. and Roche, F.M. and Frieman, M. and Stevenson, N.J., Inhibition of the IFN-α JAK/STAT Pathway by MERS-CoV and SARS-CoV-1 Proteins in Human Epithelial Cells, Viruses, 14, (4), 2022
Journal Article; Published; Peer Reviewed; Author Profile: STEVENNJ; DOI; URL

Mannion JM, McLoughlin RM, Lalor SJ, The Airway Microbiome-IL-17 Axis: a Critical Regulator of Chronic Inflammatory Disease, Clinical Reviews in Allergy & Immunology,, March 11, 2022
Journal Article; Published; Peer Reviewed; Author Profile: MCLOUGRM; DOI

Cooper AJR, Clegg J, Cassidy FC, Hogan AE, McLoughlin RM., Human MAIT Cells Respond to Staphylococcus aureus with Enhanced Anti-Bacterial Activity., Microorganisms, 10, (1), 2022
Journal Article; Published; Peer Reviewed; Author Profile: MCLOUGRM; DOI

Marilena Karavyraki, Richard K. Porter, Evidence of a role for interleukin-6 in anoikis resistance in oral squamous cell carcinoma., Medical Oncology, 2022
Journal Article; In_press; Peer Reviewed; Author Profile: RKPORTER; DOI

Hyesoo Jeon and Jerrard M. Hayes and K. H. Mok, In Silico Analysis of Therapeutic Antibody Aggregation and the Influence of Glycosylation, Glycosylation, 2022, p169--183
Journal Article; Published; Peer Reviewed; Author Profile: MOK1; DOI

Hough, K. and Verschuur, C.A. and Cunningham, C. and Newman, T.A., Macrophages in the cochlea; an immunological link between risk factors and progressive hearing loss, GLIA, 70, (2), 2022, p219-238
Journal Article; Published; Peer Reviewed; Author Profile: CUNNINCO; DOI; URL

Gu L, Casserly D, Brady G, Carpenter S, Bracken AP, Fitzgerald KA, Unterholzner L, Bowie AG., Myeloid cell nuclear differentiation antigen controls the pathogen-stimulated type I interferon cascade in human monocytes by transcriptional regulation of IRF7., Nature communications, 13, (1), 2022, p14
Journal Article; Published; Peer Reviewed; Author Profiles: BRACKEA BRADYG1 AGBOWIE ; DOI

McElroy AN, Invernizzi R, Laskowska JW, O'Neill A, Doroudian M, Moghoofei M, Mostafaei S, Li F, Przybylski AA, O'Dwyer DN, Bowie AG, Fallon PG, Maher TM, Hogaboam CM, Molyneaux PL, Hirani N, Armstrong ME, Donnelly SC., Candidate Role for Toll-like Receptor 3 L412F Polymorphism and Infection in Acute Exacerbation of Idiopathic Pulmonary Fibrosis., American journal of respiratory and critical care medicine, 2022
Journal Article; Published; Peer Reviewed; Author Profile: AGBOWIE; DOI

Marzaioli V, Canavan M, Floudas A, Flynn K, Mullan R, Veale DJ, Fearon U., CD209/CD14+ Dendritic Cells Characterization in Rheumatoid and Psoriatic Arthritis Patients: Activation, Synovial Infiltration, and Therapeutic Targeting., Frontiers in Immunology, 2022
Journal Article; Published; Peer Reviewed; Author Profiles: CANAVAM1 FEARONU

McDonnell, C.M. and Ghanim, M. and Mike Southern, J. and Kelly, V.P. and Connon, S.J., De-novo designed β-lysine derivatives can both augment and diminish the proliferation rates of E. coli through the action of Elongation Factor P, Bioorganic and Medicinal Chemistry Letters, 59, (128545), 2022
Journal Article; Published; Peer Reviewed; Author Profiles: SOUTHERJ KELLYVP ; DOI; URL

Laura K Finnegan, Naomi Chadderton, Paul F Kenna, Arpad Palfi, Michael Carty, Andrew G Bowie, Sophia Millington-Ward, Gwyneth Jane Farrar, SARM1 Ablation Is Protective and Preserves Spatial Vision in an In Vivo Mouse Model of Retinal Ganglion Cell Degeneration, International Journal of Molecular Sciences, 2022
Journal Article; Published; Peer Reviewed; Author Profiles: AGBOWIE GJFARRAR ; URL

Ryan, L. and Mills, K.H.G., Sex differences regulate immune responses in experimental autoimmune encephalomyelitis and multiple sclerosis, European Journal of Immunology, 52, (1), 2022, p24-33
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI; URL

Lynch RI, Lavelle EC., Immuno-modulatory biomaterials as anti-inflammatory therapeutics., Biochemical pharmacology, 197, 2022, p114890
Journal Article; Published; Peer Reviewed; Author Profile: LAVELLEE; DOI

Rebecca Amet, Viola Previtali, Helene B. Mihigo, Emily Sheridan, Sarah Brophy , Nadhim Kamil Hante, Maria Jose Santos-Martinez, Patrick J. Hayden, Paul V. Browne, Isabel Rozas, Anthony M. McElligott , Daniela M. Zisterer , A novel aryl-guanidinium derivative, VP79s, targets the signal transducer and activator of transcription 3 signaling pathway, downregulates myeloid cell leukaemia-1 and exhibits preclinical activity against multiple myeloma , Life Sciences, 290, 2022
Journal Article; Published; Peer Reviewed; Author Profiles: DZISTRER ROZASI MCELLIGA ; DOI

Townsend L, Dyer AH, Naughton A, Imangaliyev S, Dunne J, Kiersey R, Holden D, Mooney A, Leavy D, Ridge K, Sugrue J, Aldoseri M, Kelliher JH, Ní Cheallaigh C, Severe COVID-19 is characterised by inflammation and immature myeloid cells early in disease progression, Heliyon, 8, (4), 2022, pe09230 - e09236
Journal Article; Published; Peer Reviewed; Author Profiles: NBOURKE DYERAD DGBYRNE MCLOUGRM