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Publications

Below is the list of peer and non peer publications from the School of Biochemistry and Immunology.

Show: AllPeer ReviewedNon Peer Reviewed
90 publications from 2020

Charles-Messance, H., Sheedy, F.J., Train to Lose: Innate Immune Memory in Metaflammation, Molecular Nutrition and Food Research, 2020
Journal Article; Published; Peer Reviewed; Author Profile: FSHEEDY

Sheedy, F.J., Divangahi, M., Targeting immunometabolism in host defence against Mycobacterium tuberculosis, Immunology, 2020
Journal Article; Published; Peer Reviewed; Author Profile: FSHEEDY

Gleeson, L.E., Roche, H.M., Sheedy, F.J., Running Title: Obesity, COVID-19 and Innate Immunometabolism, British Journal of Nutrition, 2020
Journal Article; Published; Peer Reviewed; Author Profile: FSHEEDY

Charles-Messance, H., Mitchelson, K.A.J., De Marco Castro, E., Sheedy, F.J., Roche, H.M., Regulating metabolic inflammation by nutritional modulation, Journal of Allergy and Clinical Immunology, 146, (4), 2020, p706-720
Journal Article; Published; Peer Reviewed; Author Profile: FSHEEDY

Hackett, E.E., Sheedy, F.J., An Army Marches on Its Stomach: Metabolic Intermediates as Antimicrobial Mediators in Mycobacterium tuberculosis Infection, Frontiers in Cellular and Infection Microbiology, 10, 2020
Journal Article; Published; Peer Reviewed; Author Profile: FSHEEDY

Kealy, Acute Inflammation Alters Brain Energy Metabolism in Mice and Humans: Role in Suppressed Spontaneous Activity, Impaired Cognition, and Delirium, Journal of Neuroscience, 2020, p10.1523/JNEUROSCI.2876-19.2020
Journal Article; Published; Peer Reviewed; Author Profile: CUNNINCO

Vare lija, D., Tipton, K.F., Davey, G.P. and McDonald, A.G., 6-Hydroxydopamine: a far from simple neurotoxin, Journal of Neural Transmission, 127, 2020, p213 - 230
Journal Article; Published; Peer Reviewed; Author Profile: AMCDONLD; DOI

Martignoni M; Benedetti M; Davey GP; Tipton KF; McDonald A, Degradation of thymic humoral factor 2 in human, rat and mouse blood: an experimental and theoretical study, BBA - Proteins and Proteomics, 2020
Journal Article; Published; Peer Reviewed; Author Profile: GDAVEY; DOI

Abascal JF, Chiaino E, Frosini M, Davey GP, Valoti , β-Naphthoflavone and Ethanol Reverse Mitochondrial Dysfunction in A Parkinsonian Model of Neurodegeneration, International Journal of Molecular Sciences , 2020
Journal Article; Published; Peer Reviewed; Author Profile: GDAVEY; DOI

Kilbride, SM, Telford, JE and Davey, GP, Complex I controls mitochondrial and plasma membrane potentials in nerve terminals, Neurochemical Research, 2020
Journal Article; Published; Peer Reviewed; Author Profile: GDAVEY; DOI

Viola Previtali , Helene B Mihigo , Rebecca Amet, Anthony M McElligott , Daniela M Zisterer , Isabel Rozas , Exploring the Anti-Cancer Mechanism of Novel 3,4'-Substituted Diaryl Guanidinium Derivatives, Pharmaceuticals (Basel), 13, (12), 2020, p485
Journal Article; Published; Peer Reviewed; Author Profiles: MCELLIGA DZISTRER ROZASI ; DOI

David K Finlay, Metabolism and NK cell anti-tumour responses , Immunometabolism, from bench to bedside, Online via Zoom (Copenhagen), 8th September, 2020, University of Copenhagen PhD programme
Invited Talk; Presented; Non Peer Reviewed; Author Profile: FINLAYD

David K Finlay, Cancer and Natural Killer cell metabolism intertwined, Abcam Cancer Metabolism conference, Online via Zoom (Cambridge), 15th June, 2020, Abcam
Invited Talk; Presented; Non Peer Reviewed; Author Profile: FINLAYD

David K Finlay, Nutrients and metabolites controlling lymphocyte responses , ImmunoMetNet meeting, Online via Zoom, 8 April, 2020, Jan van den Bossche
Invited Talk; Published; Non Peer Reviewed; Author Profile: FINLAYD

David K Finlay, Shaping immune responses by targeting Immunometabolism , British Transplantation Society conference, Belfast, 5 March, 2020
Invited Talk; Published; Non Peer Reviewed; Author Profile: FINLAYD

David K Finlay, Nutrients and metabolites controlling lymphocyte responses , Seminar, Centro de Biología Molecular Severo Ochoa, 28 Feb, 2020, Centro de Biología Molecular Severo Ochoa
Invited Talk; Presented; Non Peer Reviewed; Author Profile: FINLAYD

Lundahl, M. and Lynch, D.M. and Barnes, D. and McSweeney, L. and Gorman, A. and Lebre, F. and Gordon, S.V. and Lavelle, E.C. and Scanlan, E.M., Mycobacterial para-Hydroxybenzoic Acid-Derivatives (pHBADs) and Related Structures Induce Macrophage Innate Memory, ACS Chemical Biology, 15, (9), 2020, p2415-2421
Journal Article; Published; Peer Reviewed; Author Profiles: SCANLAE LAVELLEE ; DOI; URL

Lavelle, E.C. and Carsetti, R. and Pickl, W.F. and Wiedermann, U., Editorial: Challenges in Vaccinology, Frontiers in Immunology, 11, (632537), 2020
Journal Article; Published; Peer Reviewed; Author Profile: LAVELLEE; DOI; URL

Williams, N.C. and O'Neill, L.A., ACLY-matizing Macrophages to Histone Modification during Immunometabolic Reprogramming, Trends in Immunology, 41, (2), 2020, p93-94
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Ryan, D.G. and O'Neill, L.A.J., Krebs Cycle Reborn in Macrophage Immunometabolism, Annual Review of Immunology, 38, 2020, p289-313
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

To, E.E. and O'Leary, J.J. and O'Neill, L.A.J. and Vlahos, R. and Bozinovski, S. and Porter, C.J.H. and Brooks, R.D. and Brooks, D.A. and Selemidis, S., Spatial Properties of Reactive Oxygen Species Govern Pathogen-Specific Immune System Responses, Antioxidants and Redox Signaling, 32, (13), 2020, p982-992
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Runtsch, M.C. and O'Neill, L.A.J., Pseudomonas Persists by Feeding off Itaconate, Cell Metabolism, 31, (6), 2020, p1045-1047
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

ZasÅ'ona, Z. and O'Neill, L.A.J., Cytokine-like Roles for Metabolites in Immunity, Molecular Cell, 78, (5), 2020, p814-823
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Hams, E. and Roberts, J. and Bermingham, R. and Hogan, A.E. and O'Shea, D. and O'Neill, L. and Fallon, P.G., Role for Retinoic Acid-Related Orphan Receptor Alpha (RORα) Expressing Macrophages in Diet-Induced Obesity, Frontiers in Immunology, 11, (1966), 2020
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

McGettrick, A.F. and O'Neill, L.A.J., The Role of HIF in Immunity and Inflammation, Cell Metabolism, 32, (4), 2020, p524-536
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Wilson, J.E., Mart, M.F., Cunningham, C. et al., Delirium, Nat Rev Dis Primers , 6, (90), 2020
Journal Article; Published; Peer Reviewed; Author Profile: CUNNINCO; DOI

Khachaturian, A.S. and Hayden, K.M. and Devlin, J.W. and Fleisher, L.A. and Lock, S.L. and Cunningham, C. and Oh, E.S. and Fong, T.G. and Fick, D.M. and Marcantonio, E.R. and Iyengar, V. and Rockwood, K. and Kuchel, G.A. and Eckenhoff, R.G. and MacLullich, A.M.J. and Jones, R.N. and Davis, D. and D'Antonio, P.M. and Fargo, K.N. and Albert, M.S. and Williamson, J.D. and Ling, S.M. and Weiss, J. and Karlawish, J. and Petersen, R.C. and Blazer, D.G. and Khachaturian, Z.S. and Inouye, S.K., International drive to illuminate delirium: A developing public health blueprint for action, Alzheimer's and Dementia, 16, (5), 2020, p711-725
Journal Article; Published; Peer Reviewed; Author Profile: CUNNINCO; DOI; URL

Oh, E.S. and Akeju, O. and Avidan, M.S. and Cunningham, C. and Hayden, K.M. and Jones, R.N. and Khachaturian, A.S. and Khan, B.A. and Marcantonio, E.R. and Needham, D.M. and Neufeld, K.J. and Rose, L. and Spence, J. and Tieges, Z. and Vlisides, P. and Inouye, S.K., A roadmap to advance delirium research: Recommendations from the NIDUS Scientific Think Tank, Alzheimer's and Dementia, 16, (5), 2020, p726-733
Journal Article; Published; Peer Reviewed; Author Profile: CUNNINCO; DOI; URL

Oldham, M.A. and Slooter, A.J.C. and Cunningham, C. and Rahman, S. and Davis, D. and Vardy, E.R.L.C. and Garcez, F.B. and Neufeld, K.J. and de Castro, R.E.V. and Ely, E.W. and MacLullich, A., Characterising neuropsychiatric disorders in patients with COVID-19, The Lancet Psychiatry, 7, (11), 2020, p932-933
Journal Article; Published; Peer Reviewed; Author Profile: CUNNINCO; DOI; URL

Wilson, J.E. and Mart, M.F. and Cunningham, C. and Shehabi, Y. and Girard, T.D. and MacLullich, A.M.J. and Slooter, A.J.C. and Ely, E.W., Publisher Correction: Delirium (Nature Reviews Disease Primers, (2020), 6, 1, (90), 10.1038/s41572-020-00223-4), Nature Reviews Disease Primers, 6, (1), 2020
Journal Article; Published; Peer Reviewed; Author Profile: CUNNINCO; DOI; URL

Massa, D. and Baran, M. and Bengoechea, J.A. and Bowie, A.G. and Voelker, D.R., PYHIN1 regulates pro-inflammatory cytokine induction rather than innate immune DNA sensing in airway epithelial cells, Journal of Biological Chemistry, 295, (14), 2020, p4438-4450
Journal Article; Published; Peer Reviewed; Author Profile: AGBOWIE; DOI; URL

van den Hoogen, B. and Santoni, A. and Sciumé, G. and Bowie, A. and O'Farrelly, C. and O'Neill, L. and Anthonsen, M. and Pardali, K. and Young, S. and Bergthaler, A. and Manel, N. and Zahn, R. and Kikkert, M. and Snijder, E. and van Kuppeveld, F. and Fouchier, R. and Hiscott, J., Immunometabolism pathways as the basis for innovative anti-viral strategies (INITIATE): A Marie Sklodowska-Curie innovative training network, Virus Research, 287, (198094), 2020
Journal Article; Published; Peer Reviewed; Author Profiles: LAONEILL AGBOWIE ; DOI; URL

Shubhangi Kandwal, Darren Fayne, Repurposing drugs for treatment of SARS-CoV-2 infection: Computational design insights into mechanisms of action, 2020
Journal Article; Published; Peer Reviewed; Author Profile: FAYNED

Malebari AM, Fayne D, Nathwani SM, O'Connell F, Noorani S, Twamley B, O'Boyle NM, O'Sullivan J, Zisterer DM, Meegan MJ, ß-Lactams with antiproliferative and antiapoptotic activity in breast and chemoresistant colon cancer cells., European journal of medicinal chemistry, 2020
Journal Article; Published; Peer Reviewed; Author Profile: FAYNED

Byrne AJ, Bright SA, McKeown JP, O'Brien JE, Twamley B, Fayne D, Williams DC, Meegan MJ, Design, Synthesis and Biochemical Evaluation of Novel Ethanoanthracenes and Related Compounds to Target Burkitt's Lymphoma., Pharmaceuticals (Basel, Switzerland), 2020
Journal Article; Published; Peer Reviewed; Author Profile: FAYNED

M. F. Rooney and Caitriona E. Curley and J. Sweeney and M. Griffin and R. K. Porter and E. Hill and L. Katz, Prolonged oral coenzyme Q10-β-cyclodextrin supplementation increases skeletal muscle complex I+III activity in young Thoroughbreds, Journal of Applied Animal Nutrition, 8, (1), 2020, p11 - 20
Journal Article; Published; Peer Reviewed; Author Profiles: ROONEYM4 RKPORTER ; URL

Finlay, C.M. and Cunningham, K.T. and Doyle, B. and Mills, K.H.G., IL-33-stimulated murine mast cells polarize alternatively activated macrophages, which suppress T cells that mediate experimental autoimmune encephalomyelitis, Journal of Immunology, 205, (7), 2020, p1909-1919
Journal Article; Published; Peer Reviewed; Author Profiles: MILLSK COFINLAY ; DOI; URL

Chasaide, C.N. and Mills, K.H.G., Next-generation pertussis vaccines based on the induction of protective t cells in the respiratory tract, Vaccines, 8, (4), 2020, p1-28
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI; URL

Locht, C. and Carbonetti, N.H. and Cherry, J.D. and Damron, F.H. and Edwards, K.M. and Fernandez, R. and Harvill, E.T. and Hozbor, D. and Mills, K.H.G. and Rodriguez, M.E. and Mascart, F., Highlights of the 12th International Bordetella Symposium, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 71, (9), 2020, p2521-2526
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI; URL

C. McKenna , R. K. Porter, C. Fitzsimons, S. M. Waters, M. McGee and D. A. Kenny, "An examination of skeletal muscle and hepatic tissue transcriptomes from beef cattle divergent for residual feed intake", Scientific Reports, submitted, 2020
Journal Article; Submitted; Peer Reviewed; Author Profile: RKPORTER

Floudas A, Neto N, Marzaioli V, Murray K, Moran B, Monaghan MG, Low C, Mullan RH, Rao N, Krishna V, Nagpal S, Veale DJ, Fearon U., Pathogenic, glycolytic PD-1+ B cells accumulate in the hypoxic RA joint., JCI insight, 5, (21), 2020
Journal Article; Published; Peer Reviewed; Author Profiles: FEARONU MORANBA ; DOI

Sulaimani J, Cluxton D, Clowry J, Petrasca A, Molloy OE, Moran B, Sweeney CM, Malara A, McNicholas N, McGuigan C, Kirby B, Fletcher JM., Dimethyl fumarate modulates the Treg-Th17 cell axis in patients with psoriasis., The British journal of dermatology, 2020
Journal Article; Published; Peer Reviewed; Author Profiles: FLETCHJ MORANBA ; DOI

Useckaite Z, Mukhopadhya A, Moran B, O'Driscoll L., Extracellular vesicles report on the MET status of their cells of origin regardless of the method used for their isolation., Scientific reports, 10, (1), 2020, p19020
Journal Article; Published; Peer Reviewed; Author Profiles: LODRISC MORANBA ; DOI; URL

Lecordier L, Uzureau S, Vanwalleghem G, Deleu M, Crowet JM, Barry P, Moran B, Voorheis P, Dumitru AC, Yamaryo-Botté Y, Dieu M, Tebabi P, Vanhollebeke B, Lins L, Botté CY, Alsteens D, Dufrêne Y, Pérez-Morga D, Nolan DP, Pays E., The Trypanosoma Brucei KIFC1 Kinesin Ensures the Fast Antibody Clearance Required for Parasite Infectivity., iScience, 23, (9), 2020, p101476
Journal Article; Published; Peer Reviewed; Author Profiles: DENOLAN MORANBA ; DOI

Fletcher JM, Moran B, Petrasca A, Smith CM., IL-17 in inflammatory skin diseases psoriasis and hidradenitis suppurativa., Clinical and experimental immunology, 201, (2), 2020, p121-134
Journal Article; Published; Peer Reviewed; Author Profiles: FLETCHJ MORANBA ; DOI

Alexander Hooftman, Stefano Angiari, Svenja Hester, Sarah E Corcoran, Marah C Runisch, Chris Ling, Melanie C Ruzek, Peter F Slivka, Anne F McGettrick, Kathy Banahan, Mark M Hughes, Alan D Irvine, Roman Fischer, Luke A J O'Neill, The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation, Cell Metabolism, 2020
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI

Hayes P., Fergus C., Ghanim M., Cirzi C., Burtnyak L., McGrenaghan C.J., Tuorto F., Nolan D.P., Kelly V.P., Queuine micronutrient deficiency promotes warburg metabolism and reversal of the mitochondrial ATP synthase in hela cells, Nutrients, 12, (3), 2020
Journal Article; Published; Peer Reviewed; Author Profiles: DENOLAN KELLYVP ; DOI

David K Finlay, What fuels Cancer Killers, Cambridge Scientific Society Seminar series, Cambridge, UK, 2020, Cambridge Scientific Society (Student society)
Invited Talk; Published; Non Peer Reviewed; Author Profile: FINLAYD

Chloe Choi and David K. Finlay, Diverse Immunoregulatory Roles of Oxysterols-the Oxidized Cholesterol Metabolites, Metabolites, 10, (10), 2020, pE384-
Review Article; Published; Peer Reviewed; Author Profile: FINLAYD; DOI

Jessica F. Walls, Jeff J. Subleski, Erika M. Palmieri, Marieli Gonzalez Cotto, Clair M. Gardiner, Daniel W. McVicar, David K. Finlay, Metabolic but not transcriptional regulation by PKM2 is important for Natural Killer cell responses, eLIFE, 2020
Journal Article; Published; Peer Reviewed; Author Profile: FINLAYD; DOI

Katie L. O'Brien, Nadine Assmann, Eimear O'Connor, Cathal Keane, Jessica Walls, Chloe Choi, Peter J. Oefner, Clair M. Gardiner, Katja Dettmer, David K. Finlay, De novo polyamine synthesis supports metabolic and functional responses in activated murine Natural Killer cells, European Journal of Immunology, 2020
Journal Article; Published; Peer Reviewed; Author Profile: FINLAYD; DOI

Liong S, Oseghale O, To EE, Brassington K, Erlich JR, Luong R, Liong F, Brooks R, Martin C, O'Toole S, Vinh A, O'Neill LAJ, Bozinovski S, Vlahos R, Papagianis PC, O'Leary JJ, Brooks DA, Selemidis S., Influenza A virus causes maternal and fetal pathology via innate and adaptive vascular inflammation in mice., Proceedings of the National Academy of Sciences of the United States of America, 2020
Journal Article; Published; Peer Reviewed; Author Profiles: CMARTIN3 SHOTOOLE LAONEILL ; DOI

A. Prasanth Saraswati,+ Nicola Relitti,+ Margherita Brindisi,+ Jeremy D. Osko, Giulia Chemi, 4 Stefano Federico, Alessandro Grillo, Simone Brogi, Niamh H. McCabe, Richard C. Turkington, 5 Ola Ibrahim, Jeffrey O'Sullivan, Stefania Lamponi, Magda Ghanim, Vincent P. Kelly, Daniela Zisterer, 6 Rebecca Amet, Patricia Hannon, Francesca Vanni, Cristina Ulivieri, Daniel Herp, Federica Sarno, 7 Antonella Di Costanzo, Fulvio Saccoccia, Giovina Ruberti, Manfred Jung, Lucia Altucci, Sandra Gemma, 8 Stefania Butini, David W. Christianson, and Giuseppe Campiani, Spiroindoline-Capped Selective HDAC6 Inhibitors: Design, 2 Synthesis, Structural Analysis, and Biological Evaluation , ACS Medicinal Chemistry Letters, 2020
Journal Article; Published; Peer Reviewed; Author Profiles: KELLYVP JOSULLI DZISTRER ; URL

Angiari, S. and Runtsch, M.C. and Sutton, C.E. and Palsson-McDermott, E.M. and Kelly, B. and Rana, N. and Kane, H. and Papadopoulou, G. and Pearce, E.L. and Mills, K.H.G. and O'Neill, L.A.J., Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+ T Cell Pathogenicity and Suppresses Autoimmunity, Cell Metabolism, 31, (2), 2020, p391-405.e8
Journal Article; Published; Peer Reviewed; Author Profiles: MILLSK LAONEILL ; DOI; URL

McGinley, A.M. and Sutton, C.E. and Edwards, S.C. and Leane, C.M. and DeCourcey, J. and Teijeiro, A. and Hamilton, J.A. and Boon, L. and Djouder, N. and Mills, K.H.G., Interleukin-17A Serves a Priming Role in Autoimmunity by Recruiting IL-1β-Producing Myeloid Cells that Promote Pathogenic T Cells, Immunity, 52, (2), 2020, p342-356.e6
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI; URL

Fitzgibbon, G. and Mills, K.H.G., The microbiota and immune-mediated diseases: Opportunities for therapeutic intervention, European Journal of Immunology, 50, (3), 2020, p326-337
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI; URL

Edwards, S.C. and Sutton, C.E. and Ladell, K. and Grant, E.J. and McLaren, J.E. and Roche, F. and Dash, P. and Apiwattanakul, N. and Awad, W. and Miners, K.L. and Lalor, S.J. and Ribot, J.C. and Baik, S. and Moran, B. and McGinley, A. and Pivorunas, V. and Dowding, L. and Macoritto, M. and Paez-Cortez, J. and Slavin, A. and Anderson, G. and Silva-Santos, B. and Hokamp, K. and Price, D.A. and Thomas, P.G. and McLoughlin, R.M. and Mills, K.H.G., A population of proinflammatory T cells coexpresses αβ and γΎ T cell receptors in mice and humans, Journal of Experimental Medicine, 217, (5), 2020
Journal Article; Published; Peer Reviewed; Author Profiles: MILLSK MORANBA ; DOI; URL

Mela, V. and Mota, B.C. and Milner, M. and McGinley, A. and Mills, K.H.G. and Kelly, Ã .M. and Lynch, M.A., Exercise-induced re-programming of age-related metabolic changes in microglia is accompanied by a reduction in senescent cells, Brain, Behavior, and Immunity, 87, 2020, p413-428
Journal Article; Published; Peer Reviewed; Author Profiles: MILLSK LYNCHMA ; DOI; URL

Damron, F.H. and Barbier, M. and Dubey, P. and Edwards, K.M. and Gu, X.-X. and Klein, N.P. and Lu, K. and Mills, K.H.G. and Pasetti, M.F. and Read, R.C. and Rohani, P. and Sebo, P. and Harvill, E.T., Overcoming waning immunity in pertussis vaccines: Workshop of the national institute of allergy and infectious diseases, Journal of Immunology, 205, (4), 2020, p877-882
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI; URL

Olwyn R. Mahon, David C. Brow, Tomas Gonzalez-Fernandez, Pierluca Pitaccoc, Ian T. Whelan, Stanislas Von E, Christopher Hobbs, Valeria Nicolosi, Kyle T. Cunningham, Kingston. H. G. Mills , Daniel J. Kelly and Aisling Dunne, Nano-particle mediated M2 macrophage polarization enhances bone formation and MSC osteogenesis in an IL-10 dependent manner, Biomaterials, 239, 2020, p119833-
Journal Article; Published; Peer Reviewed; Author Profiles: AIDUNNE MILLSK NICOLOV KELLYD9 ; DOI

Eóin C. O'Brien, Carla A. White, Jason Wyse, Emma Leacy, Richard K. Porter, Mark A. Little, Fionnuala B. Hickey, Pro-inflammatory Stimulation of Monocytes by ANCA Is Linked to Changes in Cellular Metabolism, Frontiers in Medicine (Rheumatology) , 7, 2020, p553-
Journal Article; Published; Peer Reviewed; Author Profile: RKPORTER; URL

Marilena Karavyraki, The role of IL-6 in anoikis resistance and metabolic programming in Oral Squamous Cell Cancer, 2020
Thesis; Published; Peer Reviewed; Author Profile: RKPORTER

Mary F Rooney, Caitriona E Curley, James Sweeney, Michael E Griffin, Richard K Porter, Emmeline W Hill, Lisa M Katz, Prolonged oral coenzyme Q10-β-cyclodextrin supplementation increases skeletal musclecomplex I+III activity in young, untrained healthy Thoroughbreds, Journal of Applied Animal Nutrition, 8, (1), 2020, p11 - 20
Journal Article; Published; Peer Reviewed; Author Profile: RKPORTER; URL

C. McKenna , R. K. Porter, C. Fitzsimons , S. M. Waters, M. McGee, D. A. Kenny, Mitochondrial abundance and function in skeletal muscle and liver from Simmental beef cattle divergent for residual feed intakee , Animal, 14, (8), 2020, p1710-1717
Journal Article; Published; Peer Reviewed; Author Profile: RKPORTER; DOI

Schijns, V., Fernández-Tejada, A., Barjaktarović, Z., Bouzalas, I., Brimnes, J., Chernysh, S., Gizurarson, S., Gursel, I., Jakopin, Z., Lawrenz, M., Nativi, C., Paul, S., Pedersen, G.K., Rosano, C., Ruiz-de-Angulo, A., Slütter, B., Thakur, A., Christensen, D. and Lavelle, E.C., Modulation of immune responses using adjuvants to facilitate therapeutic vaccination. , Immunological Reviews , 2020
Journal Article; Published; Peer Reviewed; Author Profile: LAVELLEE

Lemoine C, Thakur A, Kraji"nik D, Guyon R, Longet S, Razim A, Górska S, Panteli" I, Ili" T, Nikoli" I, Lavelle EC, Gamian A, Savi" S, Milicic A., Technological Approaches for Improving Vaccination Compliance and Coverage., Vaccines, 8, (2), 2020, pE304-
Journal Article; Published; Peer Reviewed; Author Profile: LAVELLEE; DOI

Schijns V, Lavelle EC., Prevention and treatment of COVID-19 disease by controlled modulation of innate immunity., European journal of immunology, 2020
Journal Article; Published; Peer Reviewed; Author Profile: LAVELLEE; DOI

Lebre F, Boland JB, Gouveia P, Gorman AL, Lundahl MLE, I Lynch R, O'Brien FJ, Coleman J, Lavelle EC., Pristine graphene induces innate immune training., Nanoscale, 12, (20), 2020, p11192-11200
Journal Article; Published; Peer Reviewed; Author Profiles: COLEMAJ LAVELLEE ; DOI

Shears RK, Jacques LC, Naylor G, Miyashita L, Khandaker S, Lebre F, Lavelle EC, Grigg J, French N, Neill DR, Kadioglu A., Exposure to diesel exhaust particles increases susceptibility to invasive pneumococcal disease., The Journal of allergy and clinical immunology, 145, (4), 2020, p1272-1284.e6
Journal Article; Published; Peer Reviewed; Author Profile: LAVELLEE; DOI

Shears, R.K., Jacques, L.C., Naylor, G., Miyashita, L., Khandaker, S., Lebre, F. and Lavelle, E.C., Grigg, J., French, N., Neill, D.R. and Kadioglu, A. , (2020). Exposure to diesel exhaust particles increases susceptibility to invasive pneumococcal disease. , J Allergy Clin Immunol., 145, (4), 2020, p1272 - 1284
Journal Article; Published; Non Peer Reviewed; Author Profile: LAVELLEE; DOI

McEntee, C.P., Moran, H.B.T., Muñoz-Wolf, N., Liddicoat, A.M., Carroll, E.C., Erbo-Wern, J., Coulter, I.S., Andersen, P., Follmann, F. and Lavelle, E.C. (2020). , Type I IFN signalling is required for cationic adjuvant formulation (CAF)01-induced cellular immunity and mucosal priming. , Vaccine, 38, (3), 2020, p635 - 643
Journal Article; Published; Peer Reviewed; Author Profile: LAVELLEE; DOI

Efstathiou C, Abidi SH, Harker J and Stevenson NJ., Revisiting Respiratory Syncytial Virus's Interaction with Host Immunity, Towards Novel Therapeutics, Cellular and Molecular Life Sciences, 2020
Journal Article; Published; Peer Reviewed; Author Profile: STEVENNJ

G. Barber, A. Anand, K. Oficjalska, J.J. Phelan, A. B. Heeran, E. Flis, N. E. Clarke, J. A. Watson, J. Strangmann, B. Flood, H. O'Neill, D. O'Toole, F. MacCarthy, N. Ravi, J. V. Reynolds, E.W. Kay, M. Quante, J. O'Sullivan, E.M. Creagh., Characterizing caspase-1 involvement during esophageal disease progression. , Cancer Immunology Immunotherapy, 69, (12), 2020, p2635 - 2649
Journal Article; Published; Peer Reviewed; Author Profiles: RAVIN REYNOLJV OSULLIJ4 ECREAGH ; DOI

Nulty C. & Creagh E.M., The Influence of Hormone Receptor Status on the Expression of Inflammatory Caspases in Tumour Microenvironment, IACR 56th Annual Conference, Galway, Ireland, 26-28 February 2020, 2020
Conference Paper; Presented; Peer Reviewed; Author Profile: ECREAGH

Flis E. & Creagh E.M., HMGB1- mediates inflammatory TLR2 pathways during oesophageal adenocarcinoma, IACR 56th Annual Conference, Galway, Ireland, 26-28 February 2020, 2020
Conference Paper; Presented; Peer Reviewed; Author Profile: ECREAGH

Z. Zas³ona , E. Flis, M.M. Wilk, R.G. Carroll, E.M. Palsson-McDermott, M.M. Hughes, C. Diskin, K. Banahan, D.G. Ryan, A. Hooftman, A. Misiak, J. Kearney, G. Lochnit, W. Bertrams, T. Greulich, B. Schmeck, O.J. McElvaney, K.H.G. Mills, E.C. Lavelle, M. Wygrecka, E.M. Creagh & L.A.J. O'Neill , Caspase-11 promotes allergic airway inflammation, Nature Communications, 2020
Journal Article; Published; Peer Reviewed; Author Profiles: LAVELLEE MILLSK ECREAGH LAONEILL ; URL

Ozaki, Ema, Gibbons, Luke, Neto, Nuno GB, Kenna, Paul, Carty, Michael, Humphries, Marian, Humphries, Pete, Campbell, Matthew, Monaghan, Michael, Bowie, Andrew and Doyle, Sarah L, SARM1 deficiency promotes rod and cone photoreceptor cell survival in a model of retinal degeneration, Life Science Alliance, 3, (5), 2020
Journal Article; Published; Peer Reviewed; Author Profiles: DOYLES8 PHUMPHRS MONAGHMI ; DOI; URL

Petrasca A, Phelan J.J., Ansboro S, Veale D.J., Fearon U., Fletcher J.M., Targeting bioenergetics prevents CD4 T cell-mediated activation of synovial fibroblasts in rheumatoid arthritis., Rheumatology, 2020
Journal Article; Published; Peer Reviewed; Author Profiles: FLETCHJ PHELANJ3 ; DOI; URL

Haidurov A and Budanov AV., Sestrin family - the stem controlling healthy ageing, Mechanisms of Ageing and Development, 2020
Journal Article; Submitted; Peer Reviewed; Author Profile: BUDANOVA

Kovaleva IE, Tokarchuk AV, Zheltukhin AO, Dalina AA, Lyamzaev KG, Haidurov A, Chumakov PM, and Budanov AV, Mitochondrial Localization and Function of SESN2, FASEBJ, Experimental Biology 2020, San Diego, April 4-7, 2020, 33, 2020
Conference Paper; In_press; Peer Reviewed; Author Profile: BUDANOVA

Mashael A. Alqasem,a Claire Fergus,a J. Mike Southern, *b Stephen J. Connon *b and Vincent P. Kelly, The eukaryotic tRNA-guanine transglycosylase enzyme inserts queuine into tRNA via a sequential bi-bi mechanism, Chemical communications, 56, 2020, p3915 - 3918
Journal Article; Published; Peer Reviewed; Author Profiles: KELLYVP SOUTHERJ ; URL

Irina E. Kovaleva, Artem V. Tokarchuk, Andrei O. Zheltukhin, Alexandra A. Dalina, Grigoriy Safronov, Aleksandra G. Evstafieva, Konstantin G. Lyamzaev,, Peter M. Chumakov2, and Andrei V. Budanov1,2*, Mitochondrial localization of SESN2, PLOS One, 15, (4), 2020, pe0226862-
Journal Article; Published; Peer Reviewed; Author Profile: BUDANOVA; DOI; URL

Segalés J, Perdiguero E, Serrano AL, Sousa-Victor P, Ortet L, Jardi M, Budanov A, Garcia-Prat L, Sandri M, Thomson D, Karin M, Lee JH, and Munoz-Canoves P., Sestrin prevents muscle atrophy from disuse and aging by integrating anabolic and catabolic signals., Nature Communications, 11, (1), 2020, p189-
Journal Article; Published; Peer Reviewed; Author Profile: BUDANOVA; DOI

Hackett, E.E., Charles-Messance, H., O'Leary, S.M., Gleeson, L.E., Muñoz-Wolf, N., Case, S., Wedderburn, A., Johnston, D.G.W., Williams, M.A., Smyth, A., Ouimet, M., Moore, K.J., Lavelle, E.C., Corr, S.C., Gordon, S.V., Keane, J., Sheedy, F.J., Mycobacterium tuberculosis Limits Host Glycolysis and IL-1ß by Restriction of PFK-M via MicroRNA-21, Cell Reports, 30, (1), 2020, p124-136.e4
Journal Article; Published; Peer Reviewed; Author Profiles: LAVELLEE FSHEEDY JOSEPHMK CORRSC ; DOI

Vare lija D, Tipton KF, Davey GP, McDonald AG, 6-Hydroxydopamine: a far from simple neurotoxin., J Neural Transm, 2020
Journal Article; Published; Peer Reviewed; Author Profile: GDAVEY; DOI

Azizah M. Malebari, Darren Fayne, Seema M. Nathwani, Fiona O'Connell, Sara Noorani, Brendan Twamley, Niamh M. O'Boyle, Jacintha O'Sullivan, Daniela M. Zisterer, Mary J. Meegan, Beta-lactams with antiproliferative and antiapoptotic activity in breast and chemoresistant colon cancer cells, European Journal of Medicinal Chemistry, 189, 2020, p112050-
Journal Article; Published; Peer Reviewed; Author Profiles: OSULLIJ4 DZISTRER NIOBOYLE FAYNED MMEEGAN ; DOI; URL

Miriam Carr, Andrew J.S. Knox, Daniel K. Nevin, Niamh O'Boyle, Shu Wang, Billy Egan, Thomas McCabe, Brendan Twamley, Daniela M. Zisterer, David G. Lloyd, Mary J. Meegan, Optimisation of Estrogen Receptor Subtype-Selectivity of a 4-Aryl-4H-Chromene Scaffold Previously Identified by Virtual Screening, Bioorganic & Medicinal Chemistry, 28, (5), 2020, p115261-
Journal Article; Published; Peer Reviewed; Author Profiles: MMEEGAN NIOBOYLE DZISTRER

Emma B. O'Connor, Natalia Muñoz-Wolf, Gemma Leon, Ed C. Lavelle, Kingston H. G. Mills, Patrick T. Walsh and Richard K. Porter, UCP3 reciprocally controls CD4+ Th17 and Treg cell differentiation, PLoS ONE, 15, (11), 2020, pe02-
Journal Article; Published; Peer Reviewed; Author Profiles: WALSHP10 LAVELLEE RKPORTER MILLSK ; DOI; URL

Aasander Frostner E, Acuna-Castroviejo D, Ahn B, Alves MG, Amati F, Aral C, Arandarcikaite O, Bailey DM, Bakker BM, Bastos Sant'Anna Silva AC, Battino M, Beard DA, Ben-Shachar D, Bishop D, Borutaite V, Breton S, Brown GC, Brown RA, Buettner GR, Burtscher J, Calabria E, Calbet JA, Calzia E, Cardoso LHD, Carvalho E, Casado Pinna M, Cervinkova Z, Chang SC, Chaurasia B, Chen Q, Chicco AJ, Chinopoulos C, Clementi E, Coen PM, Collin A, Crisostomo L, Das AM, Davis MS, De Palma C, Dias TR, Distefano G, Doerrier C, Drahota Z, Duchen MR, Ehinger J, Elmer E, Endlicher R, Fell DA, Ferko M, Ferreira JCB, Filipovska A, Fisar Z, Fischer M, Fisher JJ, Fornaro M, Galkin A, Garcia-Roves PM, Garcia-Souza LF, Garten A, Genova ML, Giovarelli M, Gonzalez-Armenta JL, Gonzalo H, Goodpaster BH, Gorr TA, Gourlay CW, Granata C, Grefte S, Haas CB, Haavik J, Han J, Harrison DK, Hellgren KT, Hernansanz-Agustin P, Holland OJ, Hoppel CL, Houstek J, Hunger M, Iglesias-Gonzalez J, Irving BA, Iyer S, Jackson CB, Jadiya P, Jang DH, Jansen-Duerr P, Jespersen NR, Jha RK, Kaambre T, Kane DA, Kappler L, Karabatsiakis A, Keijer J, Keppner G, Klingenspor M, Komlodi T, Koopman WJH, Kopitar-Jerala N, Krako Jakovljevic N, Kuang J, Kucera O, Labieniec-Watala M, Lai N, Laner V, Larsen TS, Lee HK, Lemieux H, Leeuwenburgh C, Lerfall J, Liu J, Lucchinetti E, MacMillan-Crow LA, Makrecka-Kuka M, Malik AN, Markova M, Menze MA, Meszaros AT, Michalak S, Moisoi N, Molina AJA, Montaigne D, Moore AL, Mracek T, Muntane J, Muntean DM, Murray AJ, Nemec M, Neuzil J, Newsom S, Nozickova K, O'Gorman D, Oliveira PF, Oliveira MT, Oliveira PJ, Orynbayeva Z, Pak YK, Palmeira CM, Patel HH, Pecina P, Pelnena D, Pereira da Silva Grilo da Silva F, Pesta D, Petit PX, Pichaud N, Piel S, Pirkmajer S, Porter RK, Pranger F, Prochownik EV, Pulinilkunnil T, Puurand M, Radenkovic F, Radi R, Ramzan R, Reboredo P, Renner-Sattler K, Robinson MM, Roesland GV, Rohlena J, Rolo AP, Ropelle ER, Rossiter HB, Rybacka-Mossakowska J, Saada A, Safaei Z, Salin K, Salvadego D, Sandi C, Scatena R, Schartner M, Scheibye-Knudsen M, Schilling JM, Schlattner U, Schoenfeld P, Schwarzer C, Scott GR, Shabalina IG, Sharma P, Sharma V, Shevchuk I, Siewiera K, Silber AM, Singer D, Smenes BT, Soares FAA, Sobotka O, Sokolova I, Spinazzi M, Stankova P, Stier A, Stocker R, Sumbalova Z, Suravajhala P, Swerdlow RH, Swiniuch D, Szabo I, Tanaka M, Tandler B, Tavernarakis N, Tepp K, Thyfault JP, Tomar D, Towheed A, Tretter L, Trifunovic A, Trivigno C, Tronstad KJ, Trougakos IP, Tyrrell DJ, Urban T, Valentine JM, Velika B, Vendelin M, Vercesi AE, Victor VM, Villena JA, Vitorino RMP, Vogt S, Volani C, Votion DM, Vujacic-Mirski K, Wagner BA, Ward ML, Watala C, Wei YH, Wieckowski MR, Williams C, Wohlwend M, Wolff J, Wuest RCI, Zaugg K, Zaugg M, Zischka H, Zorzano A, Supporting:, Bernardi P, Boetker HE, Borsheim E, Bouitbir J, Coker RH, Dubouchaud H, Durham WJ, Dyrstad SE, Engin AB, Gan Z, Garlid KD, Haendeler J, Hand SC, Hepple RT, Hickey AJ, Hoel F, Kainulainen H, Khamoui AV, Kowaltowski AJ, Krajcova A, Lane N, Lenaz G, Liu SS, Mazat JP, Methner A, Nedergaard J, Pallotta ML, Parajuli N, Pettersen IKN, Porter C, Sazanov LA, Skolik R, Sonkar VK, Vieyra A, Mitochondrial physiology. , Bioenergetics Communications, 2020
Journal Article; Published; Peer Reviewed; Author Profile: RKPORTER; URL

Creagh, E.M., Kay, E.W., Flood, B., Oficjalska, K., Doherty, G. and Ryan, E., 'Method And Kit For Identification Of Inflamed And Malignant Intestinal Tissue', Trinity Technical Transfer Office, EP14182681.8 , 2020, Trinity College
Patent; Granted; Peer Reviewed; Author Profile: ECREAGH