Publications
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116 publications from 2020
Mimmi Lundahl, Dylan M. Lynch, Danielle Barnes, Lauren McSweeney, Aoife Gorman, Filipa Lebre, Stephen V. Gordon, Ed C. Lavelle, Eoin M. Scanlan, Mycobacterial para-Hydroxybenzoic Acid-Derivatives (pHBADs) and Related Structures Induce Macrophage Innate Memory, ACS Chemical Biology, 2020
Craig P. McEntee, Hannah B.T. Moran, Natalia Muñoz-Wolf, Alex M. Liddicoat, Elizabeth C. Carroll, Jeanette Erbo-Wern, Ivan S. Coulter, Peter Andersen, Frank Follmann, Ed C. Lavelle, Type I IFN signalling is required for cationic adjuvant formulation (CAF)01-induced cellular immunity and mucosal priming, Vaccine, 38, (3), 2020, p635--643
Malebari, A.M. and Fayne, D. and Nathwani, S.M. and O'Connell, F. and Noorani, S. and Twamley, B. and O'Boyle, N.M. and O'Sullivan, J. and Zisterer, D.M. and Meegan, M.J., β-Lactams with antiproliferative and antiapoptotic activity in breast and chemoresistant colon cancer cells, European Journal of Medicinal Chemistry, 189, (112050), 2020
Canavan M, Wade SM, Veale DJ, Fearon U, Response to: 'Polyfunctional TEM cells in psoriatic arthritis synovium skewed towards Th17 cells' by Raychaudhuri et al., Annals of the rheumatic diseases, 2020
PÃ¥lsson-McDermott, E.M. and Oâ Neill, L.A.J., Targeting immunometabolism as an anti-inflammatory strategy, Cell Research, 30, (4), 2020, p300-314
Oâ Neill, L.A.J. and Netea, M.G., BCG-induced trained immunity: can it offer protection against COVID-19?, Nature Reviews Immunology, 20, (6), 2020, p335-337
Murphy, M.P. and Oâ Neill, L.A.J., How should we talk about metabolism?, Nature Immunology, 21, (7), 2020, p713-715
Relitti, N. and Saraswati, A.P. and Federico, S. and Khan, T. and Brindisi, M. and Zisterer, D. and Brogi, S. and Gemma, S. and Butini, S. and Campiani, G., Telomerase-based cancer therapeutics: A review on their clinical trials, Current Topics in Medicinal Chemistry, 20, (6), 2020, p433-457
Khan, T. and Relitti, N. and Brindisi, M. and Magnano, S. and Zisterer, D. and Gemma, S. and Butini, S. and Campiani, G., Autophagy modulators for the treatment of oral and esophageal squamous cell carcinomas, Medicinal Research Reviews, 40, (3), 2020, p1002-1060
Malebari, A.M. and Fayne, D. and Nathwani, S.M. and O'Connell, F. and Noorani, S. and Twamley, B. and O'Boyle, N.M. and O'Sullivan, J. and Zisterer, D.M. and Meegan, M.J., Beta-Lactams with antiproliferative and antiapoptotic activity in breast and chemoresistant colon cancer cells, European Journal of Medicinal Chemistry, 189, (112050), 2020
O'Brien MB, McLoughlin RM, Meade KG, Application of the TruCulture® whole blood stimulation system for immune response profiling in cattle., Veterinary immunology and immunopathology, 2020
Kelly AM, McLoughlin RM, Target the Host, Kill the Bug; Targeting Host Respiratory Immunosuppressive Responses as a Novel Strategy to Improve Bacterial Clearance During Lung Infection., Frontiers in immunology, 2020
Cooper AJR, Lalor SJ, McLoughlin RM, Activation of Human V"2+ "" T Cells by Staphylococcus aureus Promotes Enhanced Anti-Staphylococcal Adaptive Immunity., Journal of immunology (Baltimore, Md. : 1950), 2020
Duggan S, Laabei M, Alnahari AA, O'Brien EC, Lacey KA, Bacon L, Heesom K, Fu CL, Otto M, Skaar E, McLoughlin RM, Massey RC, A Small Membrane Stabilizing Protein Critical to the Pathogenicity of Staphylococcus aureus., Infection and immunity, 2020
Mulcahy ME, O'Brien EC, O'Keeffe KM, Vozza EG, Leddy N, McLoughlin RM, Manipulation of Autophagy and Apoptosis Facilitates Intracellular Survival of Staphylococcus aureus in Human Neutrophils., Frontiers in immunology, 2020
Clegg J, Soldaini E, Bagnoli F, McLoughlin RM, Targeting Skin-Resident Memory T Cells via Vaccination to Combat Staphylococcus aureus Infections., Trends in immunology, 2020
Do-Hyoung Kim, Jongchan Lee, K. Mok, Jung Lee, Kyou-Hoon Han, Salient Features of Monomeric Alpha-Synuclein Revealed by NMR Spectroscopy, Biomolecules, 10, (3), 2020, p428
Foley, C., Floudas, A., Canavan, M., Biniecka, M., MacDermott, E. J., Veale, D. J., Mullan, R. H., Killeen, O. G., Fearon, U., Increased T Cell Plasticity With Dysregulation of Follicular Helper T, Peripheral Helper T, and Treg Cell Responses in Children With Juvenile Idiopathic Arthritis and Down Syndrome"Associated Arthritis, Arthritis & Rheumatology, 72, (4), 2020, p677-686
Charles-Messance, H., Sheedy, F.J., Train to Lose: Innate Immune Memory in Metaflammation, Molecular Nutrition and Food Research, 2020
Sheedy, F.J., Divangahi, M., Targeting immunometabolism in host defence against Mycobacterium tuberculosis, Immunology, 2020
Gleeson, L.E., Roche, H.M., Sheedy, F.J., Running Title: Obesity, COVID-19 and Innate Immunometabolism, British Journal of Nutrition, 2020
Charles-Messance, H., Mitchelson, K.A.J., De Marco Castro, E., Sheedy, F.J., Roche, H.M., Regulating metabolic inflammation by nutritional modulation, Journal of Allergy and Clinical Immunology, 146, (4), 2020, p706-720
Hackett, E.E., Sheedy, F.J., An Army Marches on Its Stomach: Metabolic Intermediates as Antimicrobial Mediators in Mycobacterium tuberculosis Infection, Frontiers in Cellular and Infection Microbiology, 10, 2020
Kealy, Acute Inflammation Alters Brain Energy Metabolism in Mice and Humans: Role in Suppressed Spontaneous Activity, Impaired Cognition, and Delirium, Journal of Neuroscience, 2020, p10.1523/JNEUROSCI.2876-19.2020
Vare lija, D., Tipton, K.F., Davey, G.P. and McDonald, A.G., 6-Hydroxydopamine: a far from simple neurotoxin, Journal of Neural Transmission, 127, 2020, p213 - 230
Martignoni M; Benedetti M; Davey GP; Tipton KF; McDonald A, Degradation of thymic humoral factor
Abascal JF, Chiaino E, Frosini M, Davey GP, Valoti , β-Naphthoflavone and Ethanol Reverse Mitochondrial Dysfunction in A Parkinsonian Model of Neurodegeneration, International Journal of Molecular Sciences , 2020
Kilbride, SM, Telford, JE and Davey, GP, Complex I controls mitochondrial and plasma membrane potentials in nerve terminals, Neurochemical Research, 2020
Viola Previtali , Helene B Mihigo , Rebecca Amet, Anthony M McElligott , Daniela M Zisterer , Isabel Rozas , Exploring the Anti-Cancer Mechanism of Novel 3,4'-Substituted Diaryl Guanidinium Derivatives, Pharmaceuticals (Basel), 13, (12), 2020, p485
David K Finlay, Metabolism and NK cell anti-tumour responses , Immunometabolism, from bench to bedside, Online via Zoom (Copenhagen), 8th September, 2020, University of Copenhagen PhD programme
David K Finlay, Cancer and Natural Killer cell metabolism intertwined, Abcam Cancer Metabolism conference, Online via Zoom (Cambridge), 15th June, 2020, Abcam
David K Finlay, Nutrients and metabolites controlling lymphocyte responses , ImmunoMetNet meeting, Online via Zoom, 8 April, 2020, Jan van den Bossche
David K Finlay, Shaping immune responses by targeting Immunometabolism , British Transplantation Society conference, Belfast, 5 March, 2020
David K Finlay, Nutrients and metabolites controlling lymphocyte responses , Seminar, Centro de Biología Molecular Severo Ochoa, 28 Feb, 2020, Centro de Biología Molecular Severo Ochoa
Marzaioli V, Canavan M, Floudas A, Wade SC, Low C, Veale DJ, Fearon U., Monocyte-Derived Dendritic Cell Differentiation in Inflammatory Arthritis Is Regulated by the JAK/STAT Axis via NADPH Oxidase Regulation., Front Immunol, Jul 7;11:1406., 2020
Canavan M, Marzaioli V, McGarry T, Bhargava V, Nagpal S, Veale DJ, Fearon U., Rheumatoid arthritis synovial microenvironment induces metabolic and functional adaptations in dendritic cells., Clin Exp Immunol, Nov;202(2):226-238., 2020
Lundahl, M. and Lynch, D.M. and Barnes, D. and McSweeney, L. and Gorman, A. and Lebre, F. and Gordon, S.V. and Lavelle, E.C. and Scanlan, E.M., Mycobacterial para-Hydroxybenzoic Acid-Derivatives (pHBADs) and Related Structures Induce Macrophage Innate Memory, ACS Chemical Biology, 15, (9), 2020, p2415-2421
Lavelle, E.C. and Carsetti, R. and Pickl, W.F. and Wiedermann, U., Editorial: Challenges in Vaccinology, Frontiers in Immunology, 11, (632537), 2020
Williams, N.C. and O'Neill, L.A., ACLY-matizing Macrophages to Histone Modification during Immunometabolic Reprogramming, Trends in Immunology, 41, (2), 2020, p93-94
Ryan, D.G. and O'Neill, L.A.J., Krebs Cycle Reborn in Macrophage Immunometabolism, Annual Review of Immunology, 38, 2020, p289-313
To, E.E. and O'Leary, J.J. and O'Neill, L.A.J. and Vlahos, R. and Bozinovski, S. and Porter, C.J.H. and Brooks, R.D. and Brooks, D.A. and Selemidis, S., Spatial Properties of Reactive Oxygen Species Govern Pathogen-Specific Immune System Responses, Antioxidants and Redox Signaling, 32, (13), 2020, p982-992
Runtsch, M.C. and O'Neill, L.A.J., Pseudomonas Persists by Feeding off Itaconate, Cell Metabolism, 31, (6), 2020, p1045-1047
ZasÅ'ona, Z. and O'Neill, L.A.J., Cytokine-like Roles for Metabolites in Immunity, Molecular Cell, 78, (5), 2020, p814-823
Hams, E. and Roberts, J. and Bermingham, R. and Hogan, A.E. and O'Shea, D. and O'Neill, L. and Fallon, P.G., Role for Retinoic Acid-Related Orphan Receptor Alpha (RORα) Expressing Macrophages in Diet-Induced Obesity, Frontiers in Immunology, 11, (1966), 2020
McGettrick, A.F. and O'Neill, L.A.J., The Role of HIF in Immunity and Inflammation, Cell Metabolism, 32, (4), 2020, p524-536
Wilson, J.E., Mart, M.F., Cunningham, C. et al., Delirium, Nat Rev Dis Primers , 6, (90), 2020
Khachaturian, A.S. and Hayden, K.M. and Devlin, J.W. and Fleisher, L.A. and Lock, S.L. and Cunningham, C. and Oh, E.S. and Fong, T.G. and Fick, D.M. and Marcantonio, E.R. and Iyengar, V. and Rockwood, K. and Kuchel, G.A. and Eckenhoff, R.G. and MacLullich, A.M.J. and Jones, R.N. and Davis, D. and D'Antonio, P.M. and Fargo, K.N. and Albert, M.S. and Williamson, J.D. and Ling, S.M. and Weiss, J. and Karlawish, J. and Petersen, R.C. and Blazer, D.G. and Khachaturian, Z.S. and Inouye, S.K., International drive to illuminate delirium: A developing public health blueprint for action, Alzheimer's and Dementia, 16, (5), 2020, p711-725
Oh, E.S. and Akeju, O. and Avidan, M.S. and Cunningham, C. and Hayden, K.M. and Jones, R.N. and Khachaturian, A.S. and Khan, B.A. and Marcantonio, E.R. and Needham, D.M. and Neufeld, K.J. and Rose, L. and Spence, J. and Tieges, Z. and Vlisides, P. and Inouye, S.K., A roadmap to advance delirium research: Recommendations from the NIDUS Scientific Think Tank, Alzheimer's and Dementia, 16, (5), 2020, p726-733
Oldham, M.A. and Slooter, A.J.C. and Cunningham, C. and Rahman, S. and Davis, D. and Vardy, E.R.L.C. and Garcez, F.B. and Neufeld, K.J. and de Castro, R.E.V. and Ely, E.W. and MacLullich, A., Characterising neuropsychiatric disorders in patients with COVID-19, The Lancet Psychiatry, 7, (11), 2020, p932-933
Wilson, J.E. and Mart, M.F. and Cunningham, C. and Shehabi, Y. and Girard, T.D. and MacLullich, A.M.J. and Slooter, A.J.C. and Ely, E.W., Publisher Correction: Delirium (Nature Reviews Disease Primers, (2020), 6, 1, (90), 10.1038/s41572-020-00223-4), Nature Reviews Disease Primers, 6, (1), 2020
Massa, D. and Baran, M. and Bengoechea, J.A. and Bowie, A.G. and Voelker, D.R., PYHIN1 regulates pro-inflammatory cytokine induction rather than innate immune DNA sensing in airway epithelial cells, Journal of Biological Chemistry, 295, (14), 2020, p4438-4450
van den Hoogen, B. and Santoni, A. and Sciumé, G. and Bowie, A. and O'Farrelly, C. and O'Neill, L. and Anthonsen, M. and Pardali, K. and Young, S. and Bergthaler, A. and Manel, N. and Zahn, R. and Kikkert, M. and Snijder, E. and van Kuppeveld, F. and Fouchier, R. and Hiscott, J., Immunometabolism pathways as the basis for innovative anti-viral strategies (INITIATE): A Marie Sklodowska-Curie innovative training network, Virus Research, 287, (198094), 2020
Shubhangi Kandwal, Darren Fayne, Repurposing drugs for treatment of SARS-CoV-2 infection: Computational design insights into mechanisms of action, 2020
Malebari AM, Fayne D, Nathwani SM, O'Connell F, Noorani S, Twamley B, O'Boyle NM, O'Sullivan J, Zisterer DM, Meegan MJ, ß-Lactams with antiproliferative and antiapoptotic activity in breast and chemoresistant colon cancer cells., European journal of medicinal chemistry, 2020
Byrne AJ, Bright SA, McKeown JP, O'Brien JE, Twamley B, Fayne D, Williams DC, Meegan MJ, Design, Synthesis and Biochemical Evaluation of Novel Ethanoanthracenes and Related Compounds to Target Burkitt's Lymphoma., Pharmaceuticals (Basel, Switzerland), 2020
M. F. Rooney and Caitriona E. Curley and J. Sweeney and M. Griffin and R. K. Porter and E. Hill and L. Katz, Prolonged oral coenzyme Q10-β-cyclodextrin supplementation increases skeletal muscle complex I+III activity in young Thoroughbreds, Journal of Applied Animal Nutrition, 8, (1), 2020, p11 - 20
Finlay, C.M. and Cunningham, K.T. and Doyle, B. and Mills, K.H.G., IL-33-stimulated murine mast cells polarize alternatively activated macrophages, which suppress T cells that mediate experimental autoimmune encephalomyelitis, Journal of Immunology, 205, (7), 2020, p1909-1919
Chasaide, C.N. and Mills, K.H.G., Next-generation pertussis vaccines based on the induction of protective t cells in the respiratory tract, Vaccines, 8, (4), 2020, p1-28
Locht, C. and Carbonetti, N.H. and Cherry, J.D. and Damron, F.H. and Edwards, K.M. and Fernandez, R. and Harvill, E.T. and Hozbor, D. and Mills, K.H.G. and Rodriguez, M.E. and Mascart, F., Highlights of the 12th International Bordetella Symposium, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 71, (9), 2020, p2521-2526
C. McKenna , R. K. Porter, C. Fitzsimons, S. M. Waters, M. McGee and D. A. Kenny, "An examination of skeletal muscle and hepatic tissue transcriptomes from beef cattle divergent for residual feed intake", Scientific Reports, submitted, 2020
Floudas A, Neto N, Marzaioli V, Murray K, Moran B, Monaghan MG, Low C, Mullan RH, Rao N, Krishna V, Nagpal S, Veale DJ, Fearon U., Pathogenic, glycolytic PD-1+ B cells accumulate in the hypoxic RA joint., JCI insight, 5, (21), 2020
Sulaimani J, Cluxton D, Clowry J, Petrasca A, Molloy OE, Moran B, Sweeney CM, Malara A, McNicholas N, McGuigan C, Kirby B, Fletcher JM., Dimethyl fumarate modulates the Treg-Th17 cell axis in patients with psoriasis., The British journal of dermatology, 2020
Useckaite Z, Mukhopadhya A, Moran B, O'Driscoll L., Extracellular vesicles report on the MET status of their cells of origin regardless of the method used for their isolation., Scientific reports, 10, (1), 2020, p19020
Lecordier L, Uzureau S, Vanwalleghem G, Deleu M, Crowet JM, Barry P, Moran B, Voorheis P, Dumitru AC, Yamaryo-Botté Y, Dieu M, Tebabi P, Vanhollebeke B, Lins L, Botté CY, Alsteens D, Dufrêne Y, Pérez-Morga D, Nolan DP, Pays E., The Trypanosoma Brucei KIFC1 Kinesin Ensures the Fast Antibody Clearance Required for Parasite Infectivity., iScience, 23, (9), 2020, p101476
Fletcher JM, Moran B, Petrasca A, Smith CM., IL-17 in inflammatory skin diseases psoriasis and hidradenitis suppurativa., Clinical and experimental immunology, 201, (2), 2020, p121-134
Sinevici N, Harte N, O'Grady I, Xie Y, Min S, Hun Mok K, O'Sullivan J., The novel therapeutic potential of bovine "-lactalbumin made lethal to tumour cells and oleic acid in oral squamous cell carcinoma., European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 2020
Zbigniew Zaslona, Ewelina Flis, Mieszko M Wilk, Richard G Carroll, Eva M Palsson-McDermott, Mark M Hughes, Ciana Diskin, Kathy Banahan, Dylan G Ryan, Alexander Hooftman, Alicja Misiak, Jay Kearney, Gunter Lochnit, Wilhelm Bertrams, Timm Greulich, Bernd Schmeck, Oliver J McElvaney, Kingston H G Mills, Ed C Lavelle, Małgorzata Wygrecka, Emma M Creagh, Luke A J O'Neill, Caspase-11 promotes allergic airway inflammation, Nature Communications, 2020
Alexander Hooftman, Stefano Angiari, Svenja Hester, Sarah E Corcoran, Marah C Runisch, Chris Ling, Melanie C Ruzek, Peter F Slivka, Anne F McGettrick, Kathy Banahan, Mark M Hughes, Alan D Irvine, Roman Fischer, Luke A J O'Neill, The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation, Cell Metabolism, 2020
Hayes P., Fergus C., Ghanim M., Cirzi C., Burtnyak L., McGrenaghan C.J., Tuorto F., Nolan D.P., Kelly V.P., Queuine micronutrient deficiency promotes warburg metabolism and reversal of the mitochondrial ATP synthase in hela cells, Nutrients, 12, (3), 2020
David K Finlay, What fuels Cancer Killers, Cambridge Scientific Society Seminar series, Cambridge, UK, 2020, Cambridge Scientific Society (Student society)
Chloe Choi and David K. Finlay, Diverse Immunoregulatory Roles of Oxysterols-the Oxidized Cholesterol Metabolites, Metabolites, 10, (10), 2020, pE384-
Jessica F. Walls, Jeff J. Subleski, Erika M. Palmieri, Marieli Gonzalez Cotto, Clair M. Gardiner, Daniel W. McVicar, David K. Finlay, Metabolic but not transcriptional regulation by PKM2 is important for Natural Killer cell responses, eLIFE, 2020
Katie L. O'Brien, Nadine Assmann, Eimear O'Connor, Cathal Keane, Jessica Walls, Chloe Choi, Peter J. Oefner, Clair M. Gardiner, Katja Dettmer, David K. Finlay, De novo polyamine synthesis supports metabolic and functional responses in activated murine Natural Killer cells, European Journal of Immunology, 2020
Liong S, Oseghale O, To EE, Brassington K, Erlich JR, Luong R, Liong F, Brooks R, Martin C, O'Toole S, Vinh A, O'Neill LAJ, Bozinovski S, Vlahos R, Papagianis PC, O'Leary JJ, Brooks DA, Selemidis S., Influenza A virus causes maternal and fetal pathology via innate and adaptive vascular inflammation in mice., Proceedings of the National Academy of Sciences of the United States of America, 2020
A. Prasanth Saraswati, Nicola Relitti, Margherita Brindisi, Jeremy D. Osko, Giulia Chemi, Stefano Federico, Alessandro Grillo, Simone Brogi, Niamh H. McCabe, Richard C. Turkington, Ola Ibrahim, Jeffrey O'Sullivan, Stefania Lamponi, Magda Ghanim, Vincent P. Kelly, Daniela Zisterer, Rebecca Amet, Patricia Hannon, Francesca Vanni, Cristina Ulivieri, Daniel Herp, Federica Sarno, Antonella Di Costanzo, Fulvio Saccoccia, Giovina Ruberti, Manfred Jung, Lucia Altucci, Sandra Gemma, Stefania Butini, David W. Christianson, and Giuseppe Campiani, Spiroindoline-Capped Selective HDAC6 Inhibitors: Design, 2 Synthesis, Structural Analysis, and Biological Evaluation , ACS Medicinal Chemistry Letters, 2020
Angiari, S. and Runtsch, M.C. and Sutton, C.E. and Palsson-McDermott, E.M. and Kelly, B. and Rana, N. and Kane, H. and Papadopoulou, G. and Pearce, E.L. and Mills, K.H.G. and O'Neill, L.A.J., Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+ T Cell Pathogenicity and Suppresses Autoimmunity, Cell Metabolism, 31, (2), 2020, p391-405.e8
McGinley, A.M. and Sutton, C.E. and Edwards, S.C. and Leane, C.M. and DeCourcey, J. and Teijeiro, A. and Hamilton, J.A. and Boon, L. and Djouder, N. and Mills, K.H.G., Interleukin-17A Serves a Priming Role in Autoimmunity by Recruiting IL-1β-Producing Myeloid Cells that Promote Pathogenic T Cells, Immunity, 52, (2), 2020, p342-356.e6
Fitzgibbon, G. and Mills, K.H.G., The microbiota and immune-mediated diseases: Opportunities for therapeutic intervention, European Journal of Immunology, 50, (3), 2020, p326-337
Edwards, S.C. and Sutton, C.E. and Ladell, K. and Grant, E.J. and McLaren, J.E. and Roche, F. and Dash, P. and Apiwattanakul, N. and Awad, W. and Miners, K.L. and Lalor, S.J. and Ribot, J.C. and Baik, S. and Moran, B. and McGinley, A. and Pivorunas, V. and Dowding, L. and Macoritto, M. and Paez-Cortez, J. and Slavin, A. and Anderson, G. and Silva-Santos, B. and Hokamp, K. and Price, D.A. and Thomas, P.G. and McLoughlin, R.M. and Mills, K.H.G., A population of proinflammatory T cells coexpresses αβ and γΎ T cell receptors in mice and humans, Journal of Experimental Medicine, 217, (5), 2020
Mela, V. and Mota, B.C. and Milner, M. and McGinley, A. and Mills, K.H.G. and Kelly, Ã .M. and Lynch, M.A., Exercise-induced re-programming of age-related metabolic changes in microglia is accompanied by a reduction in senescent cells, Brain, Behavior, and Immunity, 87, 2020, p413-428
Damron, F.H. and Barbier, M. and Dubey, P. and Edwards, K.M. and Gu, X.-X. and Klein, N.P. and Lu, K. and Mills, K.H.G. and Pasetti, M.F. and Read, R.C. and Rohani, P. and Sebo, P. and Harvill, E.T., Overcoming waning immunity in pertussis vaccines: Workshop of the national institute of allergy and infectious diseases, Journal of Immunology, 205, (4), 2020, p877-882
Olwyn R. Mahon, David C. Brow, Tomas Gonzalez-Fernandez, Pierluca Pitaccoc, Ian T. Whelan, Stanislas Von E, Christopher Hobbs, Valeria Nicolosi, Kyle T. Cunningham, Kingston. H. G. Mills , Daniel J. Kelly and Aisling Dunne, Nano-particle mediated M2 macrophage polarization enhances bone formation and MSC osteogenesis in an IL-10 dependent manner, Biomaterials, 239, 2020, p119833-
Eóin C. O'Brien, Carla A. White, Jason Wyse, Emma Leacy, Richard K. Porter, Mark A. Little, Fionnuala B. Hickey, Pro-inflammatory Stimulation of Monocytes by ANCA Is Linked to Changes in Cellular Metabolism, Frontiers in Medicine (Rheumatology) , 7, 2020, p553-
Marilena Karavyraki, The role of IL-6 in anoikis resistance and metabolic programming in Oral Squamous Cell Cancer, 2020
Mary F Rooney, Caitriona E Curley, James Sweeney, Michael E Griffin, Richard K Porter, Emmeline W Hill, Lisa M Katz, Prolonged oral coenzyme Q10-β-cyclodextrin supplementation increases skeletal musclecomplex I+III activity in young, untrained healthy Thoroughbreds, Journal of Applied Animal Nutrition, 8, (1), 2020, p11 - 20
C. McKenna , R. K. Porter, C. Fitzsimons , S. M. Waters, M. McGee, D. A. Kenny, Mitochondrial abundance and function in skeletal muscle and liver from Simmental beef cattle divergent for residual feed intakee , Animal, 14, (8), 2020, p1710-1717
Schijns, V., Fernández-Tejada, A., Barjaktarović, Z., Bouzalas, I., Brimnes, J., Chernysh, S., Gizurarson, S., Gursel, I., Jakopin, Z., Lawrenz, M., Nativi, C., Paul, S., Pedersen, G.K., Rosano, C., Ruiz-de-Angulo, A., Slütter, B., Thakur, A., Christensen, D. and Lavelle, E.C., Modulation of immune responses using adjuvants to facilitate therapeutic vaccination. , Immunological Reviews , 2020
Lemoine C, Thakur A, Kraji"nik D, Guyon R, Longet S, Razim A, Górska S, Panteli" I, Ili" T, Nikoli" I, Lavelle EC, Gamian A, Savi" S, Milicic A., Technological Approaches for Improving Vaccination Compliance and Coverage., Vaccines, 8, (2), 2020, pE304-
Schijns V, Lavelle EC., Prevention and treatment of COVID-19 disease by controlled modulation of innate immunity., European journal of immunology, 2020
Lebre F, Boland JB, Gouveia P, Gorman AL, Lundahl MLE, I Lynch R, O'Brien FJ, Coleman J, Lavelle EC., Pristine graphene induces innate immune training., Nanoscale, 12, (20), 2020, p11192-11200
Shears RK, Jacques LC, Naylor G, Miyashita L, Khandaker S, Lebre F, Lavelle EC, Grigg J, French N, Neill DR, Kadioglu A., Exposure to diesel exhaust particles increases susceptibility to invasive pneumococcal disease., The Journal of allergy and clinical immunology, 145, (4), 2020, p1272-1284.e6
Shears, R.K., Jacques, L.C., Naylor, G., Miyashita, L., Khandaker, S., Lebre, F. and Lavelle, E.C., Grigg, J., French, N., Neill, D.R. and Kadioglu, A. , Exposure to diesel exhaust particles increases susceptibility to invasive pneumococcal disease. , J Allergy Clin Immunol., 145, (4), 2020, p1272 - 1284
McEntee, C.P., Moran, H.B.T., Muñoz-Wolf, N., Liddicoat, A.M., Carroll, E.C., Erbo-Wern, J., Coulter, I.S., Andersen, P., Follmann, F. and Lavelle, E.C. (2020). , Type I IFN signalling is required for cationic adjuvant formulation (CAF)01-induced cellular immunity and mucosal priming. , Vaccine, 38, (3), 2020, p635 - 643
Efstathiou C, Abidi SH, Harker J and Stevenson NJ., Revisiting Respiratory Syncytial Virus's Interaction with Host Immunity, Towards Novel Therapeutics, Cellular and Molecular Life Sciences, 2020
G. Barber, A. Anand, K. Oficjalska, J.J. Phelan, A. B. Heeran, E. Flis, N. E. Clarke, J. A. Watson, J. Strangmann, B. Flood, H. O'Neill, D. O'Toole, F. MacCarthy, N. Ravi, J. V. Reynolds, E.W. Kay, M. Quante, J. O'Sullivan, E.M. Creagh., Characterizing caspase-1 involvement during esophageal disease progression. , Cancer Immunology Immunotherapy, 69, (12), 2020, p2635 - 2649
Nulty C. & Creagh E.M., The Influence of Hormone Receptor Status on the Expression of Inflammatory Caspases in Tumour Microenvironment, IACR 56th Annual Conference, Galway, Ireland, 26-28 February 2020, 2020
Flis E. & Creagh E.M., HMGB1- mediates inflammatory TLR2 pathways during oesophageal adenocarcinoma, IACR 56th Annual Conference, Galway, Ireland, 26-28 February 2020, 2020
Z. Zas³ona , E. Flis, M.M. Wilk, R.G. Carroll, E.M. Palsson-McDermott, M.M. Hughes, C. Diskin, K. Banahan, D.G. Ryan, A. Hooftman, A. Misiak, J. Kearney, G. Lochnit, W. Bertrams, T. Greulich, B. Schmeck, O.J. McElvaney, K.H.G. Mills, E.C. Lavelle, M. Wygrecka, E.M. Creagh & L.A.J. O'Neill , Caspase-11 promotes allergic airway inflammation, Nature Communications, 2020
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WALLS, JESSICA , PKM2 regulation of metabolism but not transcription is important for natural killer cell responses, Trinity College Dublin.School of Biochemistry & Immunology, 2020
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Creagh, E.M., Kay, E.W., Flood, B., Oficjalska, K., Doherty, G. and Ryan, E., 'Method And Kit For Identification Of Inflamed And Malignant Intestinal Tissue', Trinity Technical Transfer Office, EP14182681.8 , 2020, Trinity College
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