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Publications

Below is the list of peer and non peer publications from the School of Biochemistry and Immunology.

Show: AllPeer ReviewedNon Peer Reviewed
131 publications from 2018

McDonald AG and Davey GP, 'On/Off Switching During The Synthesis Of Complex Sugars', Science Trends, 2018, -
Digital research resource production; Published; Non Peer Reviewed; Author Profile: GDAVEY; DOI; URL

Mary F. Rooney, Caitriona E. Curley, Michael E. Griffin, Lisa M. Katz, Richard K. Porter, Emmeline W. Hill, Dietary supplementation with MicroActive Coenzyme Q10 increases plasma and skeletal muscle Coenzyme Q10 levels in Thoroughbred horses that are genetically variable for basal Coenzyme Q10 activity levels, Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1859, 2018, pe62--e63
Journal Article; Published; Peer Reviewed; Author Profile: ROONEYM4; DOI

Mary F. Rooney, Emmeline W. Hill, Vincent P. Kelly, Richard K. Porter, Chris Rogers, The "speed gene" effect of myostatin arises in Thoroughbred horses due to a promoter proximal SINE insertion, PLOS ONE, 13, (10), 2018, pe0205664
Journal Article; Published; Peer Reviewed; Author Profile: ROONEYM4; DOI

Clarke, K.J. and Porter, R.K., The importance of calcium ions for determining mitochondrial glycerol-3-phosphate dehydrogenase activity when measuring uncoupling protein 1 (UCP1) function in mitochondria isolated from brown adipose tissue, Methods in Molecular Biology, 1782, 2018, p325-336
Journal Article; Published; Peer Reviewed; Author Profile: RKPORTER; DOI; URL

David K Finlay, What fuels Natural Killer cells against Cancer, Trinity Week Symposium , Exam Hall, TCD, 2018
Invited Talk; Published; Non Peer Reviewed; Author Profile: FINLAYD

David K Finlay, What fuels NK cells to destroy tumours?, Trinity Biomedical Frontiers Series, Trinity Biomedical Sciences Institute, 2018
Invited Talk; Published; Non Peer Reviewed; Author Profile: FINLAYD

Dalina AA, Kovaleva IE, and Budanov AV., Sestrins are Gatekeepers in the Way from Stress to Aging and Disease., Molecular Biology, 52, (6), 2018, p823 - 835
Journal Article; Published; Peer Reviewed; Author Profile: BUDANOVA; DOI

Budanov A, Evstafieva A, Dalina A, Kovaleva I, Zheltukhin A, Chumakov P, Taylor J., Sestrin2 protects against cell death in response to DNA-damaging drugs through regulation of ROS and mitochondrial function., FEBS Open Bio, FEBS 2018, Prague, Czech Republic, July 7-12, 2018, 8, (342), 2018, pp10-149-T-
Conference Paper; Published; Peer Reviewed; Author Profile: BUDANOVA; URL

Zeltukhin AO, Ilyinskaya GV, Budanov AV, and Chumakov PM., Some Phenotypic Characteristics of Nematode Caenorhabditis elegans Strains with Defective Functions of the Sestrin (cSesn) gene., Biomedical & Pharmacology Journal, 11, (2), 2018, p759 - 767
Journal Article; Published; Peer Reviewed; Author Profile: BUDANOVA; DOI

Evstafieva AG, Kovaleva IE, Shoshinova MS, Budanov AV, and Chumakov PM., Implication of KRT16, FAM129A and HKDC1 genes as ATF4 regulated components of the integrated stress response., PLOS one, 13, (2), 2018, pe0191107-
Journal Article; Published; Peer Reviewed; Author Profile: BUDANOVA; DOI

Budanov AV, Ding B, Parmigiani A, Chumakov PM, Lee JH, Chawla A, Grossman S., Sestrin2 supports lung tumor growth in early stages of cancer development in mice but might play a tumor suppressive role in the late stages of carcinogenesis., FASEB Journal, Experimental Biology 2018, San Diego, April 21-25, 32, (1), 2018, ppS Lb150-
Conference Paper; Published; Peer Reviewed; Author Profile: BUDANOVA; URL

Magnano, S., O'Sullivan, J. and Zisterer, D.M., Role of Autophagy in Chemoresistance in Oral Squamous Cell Carcinoma, International Association for Dental Research, London, England, 25 July , 2018
Invited Talk; Presented; Non Peer Reviewed; Author Profile: DZISTRER

De San Luis, C.O. and Ryan, T.J., United States of amnesia: rescuing memory loss from diverse conditions, DMM Disease Models and Mechanisms, 11, (5), 2018
Journal Article; Published; Peer Reviewed; Author Profile: TRYAN6; DOI; URL

Ortega-de San Luis, C. and Ryan, T.J., United states of amnesia: rescuing memory loss from diverse conditions, Disease models & mechanisms, 11, (5), 2018
Journal Article; Published; Peer Reviewed; Author Profile: TRYAN6; DOI; URL

McKay, S. and Ryan, T.J. and McQueen, J. and Indersmitten, T. and Marwick, K.F.M. and Hasel, P. and Kopanitsa, M.V. and Baxter, P.S. and Martel, M.-A. and Kind, P.C. and Wyllie, D.J.A. and O'Dell, T.J. and Grant, S.G.N. and Hardingham, G.E. and Komiyama, N.H., The Developmental Shift of NMDA Receptor Composition Proceeds Independently of GluN2 Subunit-Specific GluN2 C-Terminal Sequences, Cell Reports, 25, (4), 2018, p841-851.e4
Journal Article; Published; Peer Reviewed; Author Profile: TRYAN6; DOI; URL

O'Neill, L. and Perdisatt, L. and O'Connor, C., Structure-property relationships for a Series of Ruthenium(II) polypyridyl complexes elucidated through raman spectroscopy, Journal of Spectroscopy, 2018, (3827130), 2018
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Lavelle, E.C. and McLachlan, J.B., Editorial overview: Immunomodulation: Striking the right balance: using immunomodulators to target infectious diseases, cancer, and autoimmunity, Current Opinion in Pharmacology, 41, 2018, pvii-ix
Journal Article; Published; Peer Reviewed; Author Profile: LAVELLEE; DOI; URL

McKenna, C. and Porter, R.K. and Keogh, K.A. and Waters, S.M. and McGee, M. and Kenny, D.A., Correction: Residual feed intake phenotype and gender affect the expression of key genes of the lipogenesis pathway in subcutaneous adipose tissue of beef cattle [J Anim Sci Biotechnol. (2018), 9 (68)] DOI: 10.1186/s40104-018-0282-9, Journal of Animal Science and Biotechnology, 9, (1), 2018
Journal Article; Published; Peer Reviewed; Author Profile: RKPORTER; DOI; URL

Adnane, M. and Kelly, P. and Chapwanya, A. and Meade, K.G. and O'Farrelly, C., Improved detection of biomarkers in cervico-vaginal mucus (CVM) from postpartum cattle, BMC Veterinary Research, 14, (1), 2018
Journal Article; Published; Peer Reviewed; Author Profile: OFARRECL; DOI; URL

Carroll R.G, ZasÅ'ona Z, Galván-Peña S, Koppe E.L, Sévin D.C, Angiari S, Triantafilou M, Triantafilou K, Modis L.K, O†Neill L.A, An unexpected link between fatty acid synthase and cholesterol synthesis in proinflammatory macrophage activation, Journal of Biological Chemistry, 293, (15), 2018, p5509 - 5521
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Hughes M.M, O†Neill L.A.J, Metabolic regulation of NLRP3, Immunological Reviews, 281, (1), 2018, p88 - 98
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Gordon R, Albornoz E.A, Christie D.C, Langley M.R, Kumar V, Mantovani S, Robertson A.A.B, Butler M.S, Rowe D.B, O†Neill L.A, Kanthasamy A.G, Schroder K, Cooper M.A, Woodruff T.M, Inflammasome inhibition prevents -synuclein pathology and dopaminergic neurodegeneration in mice, Science Translational Medicine, 10, (465), 2018
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Olagnier D, Brandtoft A.M, Gunderstofte C, Villadsen N.L, Krapp C, Thielke A.L, Laustsen A, Peri S, Hansen A.L, Bonefeld L, Thyrsted J, Bruun V, Iversen M.B, Lin L, Artegoitia V.M, Su C, Yang L, Lin R, Balachandran S, Luo Y, Nyegaard M, Marrero B, Goldbach-Mansky R, Motwani M, Ryan D.G, Fitzgerald K.A, O†Neill L.A, Hollensen A.K, Damgaard C.K, de Paoli F, Bertram H.C, Jakobsen M.R, Poulsen T.B, Holm C.K, Nrf2 negatively regulates STING indicating a link between antiviral sensing and metabolic reprogramming, Nature Communications, 9, (1), 2018
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Boland C, Olatunji S, Bailey J, Howe N, Weichert D, Fetics S.K, Yu X, Merino-Gracia J, Delsaut C, Caffrey M, Membrane (and Soluble) Protein Stability and Binding Measurements in the Lipid Cubic Phase Using Label-Free Differential Scanning Fluorimetry, Analytical Chemistry, 90, (20), 2018, p12152 - 12160
Journal Article; Published; Peer Reviewed; Author Profile: MCAFFRE; DOI; URL

Skelly, D.T., Griffin, É.W., Murray, C.L., (...), Bannerman, D.M., Cunningham, C. , Acute transient cognitive dysfunction and acute brain injury induced by systemic inflammation occur by dissociable IL-1-dependent mechanisms, Molecular Psychiatry, 2018, p1-
Journal Article; Published; Peer Reviewed; Author Profile: CUNNINCO; DOI

Arora R.C, Cunningham C, Losing sleep over delirium, Critical Care Medicine, 46, (6), 2018, p1036 - 1038
Journal Article; Published; Peer Reviewed; Author Profile: CUNNINCO; DOI; URL

Hayden K.M, Inouye S.K, Cunningham C, Jones R.N, Avidan M.S, Davis D, Kuchel G.A, Tang Y, Khachaturian A.S, Reduce the burden of dementia now, Alzheimer's and Dementia, 14, (7), 2018, p845 - 847
Journal Article; Published; Peer Reviewed; Author Profile: CUNNINCO; DOI; URL

Wu D, Hu D, Chen H, Shi G, Fetahu I.S, Wu F, Rabidou K, Fang R, Tan L, Xu S, Liu H, Argueta C, Zhang L, Mao F, Yan G, Chen J, Dong Z, Lv R, Xu Y, Wang M, Ye Y, Zhang S, Duquette D, Geng S, Yin C, Lian C.G, Murphy G.F, Adler G.K, Garg R, Lynch L, Yang P, Li Y, Lan F, Fan J, Shi Y, Shi Y.G, Glucose-regulated phosphorylation of TET2 by AMPK reveals a pathway linking diabetes to cancer, Nature, 559, (7715), 2018, p637 - 641
Journal Article; Published; Peer Reviewed; Author Profile: LYNCHL3; DOI; URL

Borkner L, Misiak A, Wilk M.M, Mills K.H.G, Azithromycin Clears Bordetella pertussis Infection in Mice but Also Modulates Innate and Adaptive Immune Responses and T Cell Memory, Frontiers in immunology, 9, 2018, p1764-
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI; URL

Dunne PJ, Maher CO, Freeley M, Petrasca A, Orikiiriza J, Dunne MR, Reidy D, O'Dea S, Loy A, Woo J, Long A, Rogers TR, Mulcahy F, Doherty DG, CD3ε expression defines functionally-distinct subsets of Vδ1 T cells in patients with HIV infection, Frontiers in Immunology, 2018
Journal Article; Published; Peer Reviewed; Author Profile: PETRASAN

Melo AM, Zhang L, Dockry EF, Petrasca A, Ghnewa YG, Morrissey ME, O'Reilly C, Bruen R, O'Meara A, Lysaght J, Zhu X, Doherty DG, Novel thioglycoside analogs of α-galactosylceramide stimulate cytotoxicity and preferential Th1 cytokine production by human invariant natural killer T cells, Frontiers in Immunology, 2018
Journal Article; Published; Peer Reviewed; Author Profile: PETRASAN

Cunningham, C. and Dunne, A. and Lopez-Rodriguez, A.B., Astrocytes: Heterogeneous and Dynamic Phenotypes in Neurodegeneration and Innate Immunity, Neuroscientist, 2018
Journal Article; Published; Peer Reviewed; Author Profiles: AIDUNNE CUNNINCO ; DOI; URL

Almahboub, S.A., Narancic, T., Fayne, D., O"Connor, K.E., Single point mutations reveal amino acid residues important for Chromobacterium violaceum transaminase activity in the production of unnatural amino acids, Scientific Reports, 8, (1), 2018
Journal Article; Published; Peer Reviewed; Author Profile: FAYNED

Early JO, Menon D, Wyse CA, Cervantes-Silva MP, Zaslona Z, Carroll RG, Palsson-McDermott EM, Angiari S, Ryan DG, Corcoran SE, Timmons G, Geiger SS, Fitzpatrick DJ, O'Connell D, Xavier RJ, Hokamp K, O'Neill LAJ, Curtis AM., Circadian clock protein BMAL1 regulates IL-1ß in macrophages via NRF2., Proceedings of the National Academy of Sciences of the United States of America, 115, (36), 2018, pE8460-E8468
Journal Article; Published; Peer Reviewed; Author Profiles: LAONEILL KAHOKAMP ; DOI

Dunphy G, Flannery SM, Almine JF, Connolly DJ, Paulus C, Jønsson KL, Jakobsen MR, Nevels MM, Bowie AG, Unterholzner L., Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-"B Signaling after Nuclear DNA Damage., Molecular cell, 71, (5), 2018, p745-760.e5
Journal Article; Published; Peer Reviewed; Author Profile: AGBOWIE; DOI

Dempsey A, Keating SE, Carty M, Bowie AG., Poxviral protein E3-altered cytokine production reveals that DExD/H-box helicase 9 controls Toll-like receptor-stimulated immune responses., The Journal of biological chemistry, 293, (39), 2018, p14989-15001
Journal Article; Published; Peer Reviewed; Author Profile: AGBOWIE; DOI

O'Neill, L.A. and Cooper, M.A., Canakinumab for Atherosclerotic Disease, The New England journal of medicine, 378, (2), 2018, p198-199
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Kammoun, H.L. and Allen, T.L. and Henstridge, D.C. and Barre, S. and Coll, R.C. and Lancaster, G.I. and Cron, L. and Reibe, S. and Chan, J.Y. and Bensellam, M. and Laybutt, D.R. and Butler, M.S. and Robertson, A.A.B. and O'Neill, L.A. and Cooper, M.A. and Febbraio, M.A., Evidence against a role for NLRP3-driven islet inflammation in db/db mice, Molecular Metabolism, 10, 2018, p66-73
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

O'Neill, L.A.J. and Zaslona, Z., Macrophages Remember Cheeseburgers and Promote Inflammation via NLRP3, Trends in Molecular Medicine, 24, (4), 2018, p335-337
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Perdisatt, L. and Moqadasi, S. and O'Neill, L. and Hessman, G. and Ghion, A. and Warraich, M.Q.M. and Casey, A. and O'Connor, C., Synthesis, characterisation and DNA intercalation studies of regioisomers of ruthenium (II) polypyridyl complexes, Journal of Inorganic Biochemistry, 182, 2018, p71-82
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Angiari, S. and O'Neill, L.A., Dimethyl fumarate: Targeting glycolysis to treat MS, Cell Research, 28, (6), 2018, p613-615
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Murphy, M.P. and O'Neill, L.A.J., Krebs Cycle Reimagined: The Emerging Roles of Succinate and Itaconate as Signal Transducers, Cell, 174, (4), 2018, p780-784
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Baardman, J. and Verberk, S.G.S. and Prange, K.H.M. and van Weeghel, M. and van der Velden, S. and Ryan, D.G. and WÃŒst, R.C.I. and Neele, A.E. and Speijer, D. and Denis, S.W. and Witte, M.E. and Houtkooper, R.H. and O'neill, L.A. and Knatko, E.V. and Dinkova-Kostova, A.T. and Lutgens, E. and de Winther, M.P.J. and Van den Bossche, J., A Defective Pentose Phosphate Pathway Reduces Inflammatory Macrophage Responses during Hypercholesterolemia, Cell Reports, 25, (8), 2018, p2044-2052.e5
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Richard K. Porter, Cellular Oxygen Consumption as an index of Metabolic Activity, CRDI Course: Techniques & Strategies in Molecular Medicine 2018, Trinity Biomedical SCience Institute (TBSI), 4-5 December , 2018, Gael Parent
Invited Talk; Published; Peer Reviewed; Author Profile: RKPORTER; URL

Creagh, E.M., Contribution of Inflammatory caspases to IBD & CRC, INITIative Network meeting, Dublin, Ireland, 23rd November 2018, 2018
Invited Talk; Presented; Non Peer Reviewed; Author Profile: ECREAGH

Flis, E and Creagh, E.M., STAT1-mediated tumour suppression is regulated by caspase-11 in a murine model of colitis-associated carcinogenesis., Toll 2018 - Editing Innate Immunity., Porto, Portugal., 2018
Poster; Presented; Peer Reviewed; Author Profile: ECREAGH

Kenealy, S. & Creagh, E.M., Novel NLRP6 mutation identified in a patient with an unexplained autoinflammatory disporder, Toll 2018 - Editing Innate Immunity., Porto, Portugal., 6-9 June 2018, 2018
Poster; Presented; Peer Reviewed; Author Profile: ECREAGH

Flis, E and Creagh, E.M., Role of TLR2 in Oesophageal Adenocarcinoma Progression, Training in Cancer Mechanisms & Therapeutics Meeting, Queens University, Belfast, 16th April 2018, 2018
Oral Presentation; Presented; Non Peer Reviewed; Author Profile: ECREAGH

Canavan M, Walsh AM, Bhargava V, Wade SM, McGarry T, Marzaioli V, Moran B, Biniecka M, Convery H, Wade S, Orr C, Mullan R, Fletcher JM, Nagpal S, Veale DJ, Fearon U, Enriched CD141+ DCs in the joint are transcriptionally distinct, activated, and contribute to joint pathogenesis., JCI Insight, 3, (23), 2018, p95228-
Journal Article; Published; Peer Reviewed; Author Profiles: MORANBA FEARONU FLETCHJ ; DOI

Richard K. Porter - Irish Times, 'Irish scientists pinpoint what makes thoroughbred racehorses go faster. https://www.irishtimes.com/news/science/irish-scientists-pinpoint-what-makes-thoroughbred-racehorses-go-faster-1.3688584', 2018, -
Broadcast; Published; Peer Reviewed; Author Profile: RKPORTER; URL

Richard K. Porter - RTE, 'Irish scientists uncover what makes a horse run fast or long. https://www.rte.ie/news/2018/1106/1008968-race-horses/', 2018, -
Broadcast; Published; Peer Reviewed; Author Profile: RKPORTER; URL

Marilena Karavyraki & Richard K. Porter, Mitochondrial function linked to metabolic differences in dysplastic and cancerous oral cells , European Bioenergetics Conference, Budapest, July, 2018
Meeting Abstract; Published; Peer Reviewed; Author Profile: RKPORTER; URL

Mary F Rooney, Emmeline W Hill, Vincent Kelly and Richard K Porter, Genotype variation at the MSTN locus is associated with skeletal muscle Coenzyme Q level in untrained Thoroughbred horses., European Bioenergetics Conference, Budapest, P2 b/22, 2018
Meeting Abstract; Published; Peer Reviewed; Author Profile: RKPORTER; URL

Caitriona E Curley, Mary F Rooney, Michael E Griffin, Lisa M Katz, Richard K Porter and Emmeline W Hill, Supplementation with MicroActive coenzyme Q10 increases plasma and skeletal muscle coenzyme Q10 levels in healthy Thoroughbred horses. , European Bioenergetics Conference, Budapest, July, P1b3, 2018
Meeting Abstract; Published; Peer Reviewed; Author Profile: RKPORTER; URL

Emma O'Connor, Richard K. Porter, Patrick T. Walsh, The Role of Mitochondrial Uncoupling Protein 3 in T Cell Function, European Bioenergetics Conference, Budapest, July, 2018, European Bioenergetics Conference
Invited Talk; Published; Peer Reviewed; Author Profile: RKPORTER; URL

Emma O'Connor, The Role of Mitochondrial Uncoupling Protein 3 in T Cell Function, TCD, 2018
Thesis; Published; Peer Reviewed; Author Profile: RKPORTER

Lebre, F., Hanlon, D., Boland, J.B., Coleman, J. and Lavelle E.C. , Exfoliation in Endotoxin‐Free Albumin Generates Pristine Graphene with Reduced Inflammatory Properties., Advanced Biosystems, 2, (12), 2018, p1800102-
Journal Article; Published; Peer Reviewed; Author Profiles: COLEMAJ LAVELLEE ; DOI

Lebre, F., Pedroso de Lima, M.C., Lavelle, E.C. and Borges, O , Mechanistic study of the adjuvant effect of chitosan-aluminum nanoparticles., International Journal of Pharmaceutics, 552, (112), 2018, p12 - 15
Journal Article; Published; Peer Reviewed; Author Profile: LAVELLEE; DOI

Moran, H.B.T., Turley, J., Andersen, M. and Lavelle, E.C , Immunomodulatory properties of chitosan polymers. , Biomaterials, 184, 2018, p1 - 9
Journal Article; Published; Peer Reviewed; Author Profile: LAVELLEE; DOI

Lavelle, E.C. and McLachlan,J., Striking the right balance: using immunomodulators to target infectious diseases, cancer and autoimmunity, Current Opinion in Pharmacology, 41, 2018, pvii - ix
Journal Article; Published; Peer Reviewed; Author Profile: LAVELLEE; DOI

Rooney M.F., Hill E.W., Kelly V.P., Porter R.K., The "speed gene" effect of myostatin arises in Thoroughbred horses due to a promoter proximal SINE insertion, PLoS ONE, 13, (10), 2018
Journal Article; Published; Peer Reviewed; Author Profiles: KELLYVP RKPORTER ROONEYM4 ; DOI

Wilk, M.M. and Mills, K.H.G., CD4 TRM cells following infection and immunization: Implications for more effective vaccine design, Frontiers in Immunology, 9, (AUG), 2018, p01860-
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI; URL

Solans, L. and Debrie, A.-S. and Borkner, L. and Aguiló, N. and Thiriard, A. and Coutte, L. and Uranga, S. and Trottein, F. and Martín, C. and Mills, K.H.G. and Locht, C., IL-17-dependent SIgA-mediated protection against nasal Bordetella pertussis infection by live attenuated BPZE1 vaccine, Mucosal Immunology, 11, (6), 2018, p1753-1762
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI; URL

Allen, A.C. and Wilk, M.M. and Misiak, A. and Borkner, L. and Murphy, D. and Mills, K.H.G., Sustained protective immunity against Bordetella pertussis nasal colonization by intranasal immunization with a vaccine-adjuvant combination that induces IL-17-secreting TRM cells, Mucosal Immunology, 11, (6), 2018, p1763-1776
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI; URL

Michelet, X. and Dyck, L. and Hogan, A. and Loftus, R.M. and Duquette, D. and Wei, K. and Beyaz, S. and Tavakkoli, A. and Foley, C. and Donnelly, R. and O†Farrelly, C. and Raverdeau, M. and Vernon, A. and Pettee, W. and O†Shea, D. and Nikolajczyk, B.S. and Mills, K.H.G. and Brenner, M.B. and Finlay, D. and Lynch, L., Metabolic reprogramming of natural killer cells in obesity limits antitumor responses, Nature Immunology, 19, (12), 2018, p1330-1340
Journal Article; Published; Peer Reviewed; Author Profiles: LYNCHL3 MILLSK ; DOI; URL

David Finlay, What fuels Natural killer cell anti-tumour responses, Centre d'Etude des Pathologies Respiratoires (CEPR) -Institute Seminar, Tours, France, 29th May, 2018, Centre d'Etude des Pathologies Respiratoires (CEPR)
Invited Talk; Presented; Non Peer Reviewed; Author Profile: FINLAYD

David Finlay, cMyc and Srebp drive glucose fueled Natural Killer responses, Translational Immunometabolism', Cell Press Sympsium, Basel, Switzerland, 24th June, 2018
Oral Presentation; Presented; Non Peer Reviewed; Author Profile: FINLAYD

David Finlay, Fueling Robust Anti-Tumor NK Cell Responses , Discovery on Target Conference; NK cell based Cancer Immunotherapies, Boston, 26 September, 2018
Invited Talk; Presented; Non Peer Reviewed; Author Profile: FINLAYD

Michelet X, Dyck L, Hogan A, Loftus LM, Duquette D, Wei K, Beyaz S,Tavakkoli A, Foley C, Donnelly R, O'Farrelly C, Raverdeau M, Vernon A, Pettee W, O'Shea D, Nikolajczyk BS, Mills KH, Brenner MB, Finlay DK and Lynch L, Metabolic reprogramming of natural killer cells in obesity prevents cytotoxicity and promotes tumor progression, Nature Immunology, 19, (12), 2018, p1330 - 1340
Journal Article; Published; Peer Reviewed; Author Profile: FINLAYD; DOI; URL

Lopez Rodriguez A., Dunne, A. and Cunningham, C, Heterogeneous and Dynamic Astrocyte phenotypes in neurodegeneration and innate immunity, The Neuroscientist, 2018, pdoi:10.1177/1073858418809941
Review; Published; Peer Reviewed; Author Profile: AIDUNNE; URL

McCarthy, G.M. and Dunne, A., Calcium Crystal Deposition Diseases - beyond gout, Nature Reviews Rheumatology, 14, 2018
Review; Published; Peer Reviewed; Author Profile: AIDUNNE; URL

Mahon, O.R. and Dunne, A., Disease associated particulates and joint inflammation; mechanistic insights and therapeutic targets, Frontiers in Immunology, 9, 2018
Review; Published; Peer Reviewed; Author Profile: AIDUNNE; URL

S. Federico, T. Khan, N. Relitti , G. Chemi, M. Brindisi , S. Brogi, E. Novellino, D.M. Zisterer, G. Campiani, S. Gemma, S. Butini, A Jocic-type approach for a practical and scalable synthesis of pyrrolonaphthoxazepine (PNOX)-based potent proapoptotic agents, Tetrahedron Letters, 2018
Journal Article; Accepted; Peer Reviewed; Author Profile: DZISTRER; DOI

Guagnini, F. and Antonik, P.M. and Rennie, M.L. and O'Byrne, P. and Khan, A.R. and Pinalli, R. and Dalcanale, E. and Crowley, P.B., Cucurbit[7]uril-Dimethyllysine Recognition in a Model Protein, Angewandte Chemie - International Edition, 57, (24), 2018, p7126-7130
Journal Article; Published; Peer Reviewed; Author Profile: AMIRRAFK; DOI; URL

David, J. and O'Toole, E. and O'Reilly, K. and Thuery, G. and Assmann, N. and Finlay, D. and Harkin, A., Inhibitors of the NMDA-Nitric Oxide Signaling Pathway Protect Against Neuronal Atrophy and Synapse Loss Provoked by L-alpha Aminoadipic Acid-treated Astrocytes, Neuroscience, 392, 2018, p38-56
Journal Article; Published; Peer Reviewed; Author Profiles: AHARKIN FINLAYD ; DOI; URL

Loftus, R.M. and Assmann, N. and Kedia-Mehta, N. and O'Brien, K.L. and Garcia, A. and Gillespie, C. and Hukelmann, J.L. and Oefner, P.J. and Lamond, A.I. and Gardiner, C.M. and Dettmer, K. and Cantrell, D.A. and Sinclair, L.V. and Finlay, D.K., Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice, Nature Communications, 9, (1), 2018
Journal Article; Published; Peer Reviewed; Author Profiles: FINLAYD GARDINEC ; DOI; URL

Campbell, N.K. and Fitzgerald, H.K. and Malara, A. and Hambly, R. and Sweeney, C.M. and Kirby, B. and Fletcher, J.M. and Dunne, A., Naturally derived Heme-Oxygenase 1 inducers attenuate inflammatory responses in human dendritic cells and T cells: Relevance for psoriasis treatment, Scientific Reports, 8, (1), 2018, p10287 -
Journal Article; Published; Peer Reviewed; Author Profiles: AIDUNNE FLETCHJ ; DOI; URL

Gleeson LE, O'Leary SM, Ryan D, McLaughlin AM, Sheedy FJ, Keane JM., Cigarette Smoking Impairs the Bioenergetic Immune Response to Mycobacterium Tuberculosis Infection., American journal of respiratory cell and molecular biology, 2018
Journal Article; Published; Peer Reviewed; Author Profiles: FSHEEDY JOSEPHMK ; DOI

McDonald A.G., Tipton K.F. and Davey G.P., A mechanism for bistability in glycosylation, PLOS Computational Biology, 14, (8), 2018, pe1006348-
Journal Article; Published; Peer Reviewed; Author Profiles: KTIPTON AMCDONLD GDAVEY ; DOI

Wiktor, M. and Caffrey, M., Biophysical characterization and stabilization of detergent-solubilized lipoprotein N-acyl transferase from P. aeruginosa and E. coli, Biochimica et Biophysica Acta - Biomembranes, 1860, (6), 2018, p1384-1393
Journal Article; Published; Peer Reviewed; Author Profile: MCAFFRE; DOI; URL

Yin, W. and Zhou, X.E. and Yang, D. and De Waal, P.W. and Wang, M. and Dai, A. and Cai, X. and Huang, C.-Y. and Liu, P. and Wang, X. and Yin, Y. and Liu, B. and Zhou, Y. and Wang, J. and Liu, H. and Caffrey, M. and Melcher, K. and Xu, Y. and Wang, M.-W. and Xu, H.E. and Jiang, Y., Crystal structure of the human 5-HT1Bserotonin receptor bound to an inverse agonist, Cell Discovery, 4, (1), 2018, p12-
Journal Article; Published; Peer Reviewed; Author Profile: MCAFFRE; DOI; URL

El Ghachi, M. and Howe, N. and Huang, C.-Y. and Olieric, V. and Warshamanage, R. and Touzé, T. and Weichert, D. and Stansfeld, P.J. and Wang, M. and Kerff, F. and Caffrey, M., Crystal structure of undecaprenyl-pyrophosphate phosphatase and its role in peptidoglycan biosynthesis, Nature Communications, 9, (1), 2018
Journal Article; Published; Peer Reviewed; Author Profile: MCAFFRE; DOI; URL

Previtali, V. and Trujillo, C. and Amet, R. and Zisterer, D.M. and Rozas, I., Effect of isouronium/guanidinium substitution on the efficacy of a series of novel anti-cancer agents, MedChemComm, 9, (4), 2018, p735-743
Journal Article; Published; Peer Reviewed; Author Profiles: DZISTRER ROZASI ; DOI; URL

Munoz-Wolf, N. and Lavelle, E.C., A Guide to IL-1 family cytokines in adjuvanticity, FEBS Journal, 285, (13), 2018, p2377 - 2401
Journal Article; Published; Peer Reviewed; Author Profile: LAVELLEE; DOI; URL

Clancy, D.M. and Sullivan, G.P. and Moran, H.B.T. and Henry, C.M. and Reeves, E.P. and McElvaney, N.G. and Lavelle, E.C. and Martin, S.J., Extracellular Neutrophil Proteases Are Efficient Regulators of IL-1, IL-33, and IL-36 Cytokine Activity but Poor Effectors of Microbial Killing, Cell Reports, 22, (11), 2018, p2809-2817
Journal Article; Published; Peer Reviewed; Author Profiles: LAVELLEE MARTINSJ ; DOI; URL

Gargan, S. and Ahmed, S. and Mahony, R. and Bannan, C. and Napoletano, S. and O'Farrelly, C. and Borrow, P. and Bergin, C. and Stevenson, N.J., HIV-1 Promotes the Degradation of Components of the Type 1 IFN JAK/STAT Pathway and Blocks Anti-viral ISG Induction, EBioMedicine, 30, 2018, p203-216
Journal Article; Published; Peer Reviewed; Author Profiles: OFARRECL STEVENNJ ; DOI; URL

Fuchs, A. and Gliwinski, M. and Grageda, N. and Spiering, R. and Abbas, A.K. and Appel, S. and Bacchetta, R. and Battaglia, M. and Berglund, D. and Blazar, B. and Bluestone, J.A. and BornhÃ"user, M. and Brinke, A. and Brusko, T.M. and Cools, N. and Cuturi, M.C. and Geissler, E. and Giannoukakis, N. and Golab, K. and Hafler, D.A. and van Ham, S.M. and Hester, J. and Hippen, K. and Di Ianni, M. and Ilic, N. and Isaacs, J. and Issa, F. and Iwaszkiewicz-Grzes, D. and Jaeckel, E. and Joosten, I. and Klatzmann, D. and Koenen, H. and Kooten, C. and Korsgren, O. and Kretschmer, K. and Levings, M. and Marek-Trzonkowska, N.M. and Martinez-Llordella, M. and Miljkovic, D. and Mills, K.H.G. and Miranda, J.P. and Piccirillo, C.A. and Putnam, A.L. and Ritter, T. and Roncarolo, M.G. and Sakaguchi, S. and Sánchez-Ramón, S. and Sawitzki, B. and Sofronic-Milosavljevic, L. and Sykes, M. and Tang, Q. and Vives-Pi, M. and Waldmann, H. and Witkowski, P. and Wood, K.J. and Gregori, S. and Hilkens, C.M.U. and Lombardi, G. and Lord, P. and Martinez-Caceres, E.M. and Trzonkowski, P., Minimum information about T regulatory cells: A step toward reproducibility and standardization, Frontiers in Immunology, 8, (JAN), 2018, p01844-
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI; URL

McGinley, A.M. and Edwards, S.C. and Raverdeau, M. and Mills, K.H.G., Th17 cells, γΎ T cells and their interplay in EAE and multiple sclerosis, Journal of Autoimmunity, 87, 2018, p16-25
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI; URL

Dyck, L. and Lynch, L., New Job for NK Cells: Architects of the Tumor Microenvironment, Immunity, 48, (1), 2018, p9-11
Journal Article; Published; Peer Reviewed; Author Profile: LYNCHL3; DOI; URL

LaMarche, N.M. and Lynch, L., Adipose Dendritic Cells Come Out of Hiding, Cell Metabolism, 27, (3), 2018, p485-486
Journal Article; Published; Peer Reviewed; Author Profile: LYNCHL3; DOI; URL

Kohlgruber, A.C. and Gal-Oz, S.T. and Lamarche, N.M. and Shimazaki, M. and Duquette, D. and Nguyen, H.N. and Mina, A.I. and Paras, T. and Tavakkoli, A. and Von Andrian, U. and Banks, A.S. and Shay, T. and Brenner, M.B. and Lynch, L., γΎ T cells producing interleukin-17A regulate adipose regulatory T cell homeostasis and thermogenesis /631/250/256 /631/250/2504 article, Nature Immunology, 19, (5), 2018, p464-474
Journal Article; Published; Peer Reviewed; Author Profile: LYNCHL3; DOI; URL

Hong, S. and Song, W. and Zushin, P.-J.H. and Liu, B. and Jedrychowski, M.P. and Mina, A.I. and Deng, Z. and Cabarkapa, D. and Hall, J.A. and Palmer, C.J. and Aliakbarian, H. and Szpyt, J. and Gygi, S.P. and Tavakkoli, A. and Lynch, L. and Perrimon, N. and Banks, A.S., Phosphorylation of Beta-3 adrenergic receptor at serine 247 by ERK MAP kinase drives lipolysis in obese adipocytes, Molecular Metabolism, 12, 2018, p25-38
Journal Article; Published; Peer Reviewed; Author Profile: LYNCHL3; DOI; URL

Jantsch, M.F., Quattrone, A., O'Connell, M., (...), Ule, J., Fray, R., Positioning Europe for the EPITRANSCRIPTOMICS challenge, RNA Biology, 2018, p1-3
Journal Article; Published; Peer Reviewed; Author Profile: KELLYVP

O'Rourke M, Fearon U, Sweeney CM, Basdeo SA, Fletcher JM, Murphy CC, Canavan M, The pathogenic role of dendritic cells in non-infectious anterior uveitis., Experimental eye research, 2018, p121 - 128
Journal Article; Published; Peer Reviewed; Author Profiles: SBASDEO FLETCHJ FEARONU ; DOI

Mills, E.L. and Ryan, D.G. and Prag, H.A. and Dikovskaya, D. and Menon, D. and Zaslona, Z. and Jedrychowski, M.P. and Costa, A.S.H. and Higgins, M. and Hams, E. and Szpyt, J. and Runtsch, M.C. and King, M.S. and McGouran, J.F. and Fischer, R. and Kessler, B.M. and McGettrick, A.F. and Hughes, M.M. and Carroll, R.G. and Booty, L.M. and Knatko, E.V. and Meakin, P.J. and Ashford, M.L.J. and Modis, L.K. and Brunori, G. and Sévin, D.C. and Fallon, P.G. and Caldwell, S.T. and Kunji, E.R.S. and Chouchani, E.T. and Frezza, C. and Dinkova-Kostova, A.T. and Hartley, R.C. and Murphy, M.P. and O'Neill, L.A., Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1, Nature, 556, (7699), 2018, p113-117
Journal Article; Published; Peer Reviewed; Author Profiles: JMCGOURA PFALLON LAONEILL ; DOI; URL

Clare McKenna, An examination of the molecular control of feed efficiency in beef cattle, 2018
Thesis; Submitted; Peer Reviewed; Author Profile: RKPORTER

Petr Je ek, Martin Jabůrek and Richard K. Porter , Uncoupling mechanism and redox regulations of mitochondrial uncoupling protein UCP1 , Biochimica Biophysica Acta, 2728, (18), 2018, p30170 - 30181
Review Article; Published; Peer Reviewed; Author Profile: RKPORTER; DOI

The role of calcium ions for determining mitochondrial glycerol-3-phosphate dehydrogenase activity when measuring uncoupling protein 1 (UCP1) function in mitochondria isolated from brown adipose tissue. in, editor(s)Carlos Palmiera , Methods in Molecular Biology , 2018, pp325-336 , [Kieran J Clarke & Richard K. Porter ]
Book Chapter; Published; Peer Reviewed; Author Profile: RKPORTER; DOI; URL

McKenna C, Porter RK, Keogh K, Waters SM, McGee M and Kenny DA, Residual feed intake phenotype and gender affect the expression of key genes of the lipogenesis pathway in adipose tissue of beef cattle, Journal of Animal Science Biotechnolology, 9, 2018, p68 - 78
Journal Article; Published; Peer Reviewed; Author Profile: RKPORTER; DOI; URL

Mary F Rooney, Emmeline W Hill, Vincent P. Kelly, Richard K. Porter , The "speed gene" effect of myostatin arises in Thoroughbred horses due to a promoter proximal SINE insertion, PLOS ONE, 13, (10), 2018, p1-20
Journal Article; Published; Peer Reviewed; Author Profile: RKPORTER; URL

Rad E, Murray JT, Tee AR., Oncogenic Signalling through Mechanistic Target of Rapamycin (mTOR): A Driver of Metabolic Transformation and Cancer Progression., Cancers, 10, (1), 2018
Journal Article; Published; Peer Reviewed; Author Profile: JMURRAY6; DOI

Runtsch, M.C. and O'Neill, L.A.J., GOTcha: LncRNA-ACOD1 targets metabolism during viral infection, Cell Research, 28, (2), 2018, p137-138
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Williams, N.C. and O'Neill, L.A.J., A role for the krebs cycle intermediate citrate in metabolic reprogramming in innate immunity and inflammation, Frontiers in Immunology, 9, (FEB), 2018, p00141-
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Cooke G, Kamal I, Strengert M, Hams E, Mawhinney L, Tynan A, O' Reilly C, O' Dwyer DN, Kunkel SL, Knaus UG, Shields DC, Moller DR, Bowie AG, Fallon PG, Hogaboam CM, Armstrong ME, Donnelly SC., Toll-like receptor 3 L412F polymorphism promotes a persistent clinical phenotype in pulmonary sarcoidosis., QJM, 2018, p217-224
Journal Article; Published; Peer Reviewed; Author Profiles: AGBOWIE PFALLON ARMSTRP ; URL

Coyle R, O'Sullivan M. & Zisterer DM, Inhibitor of Apoptosis Proteins as Targets for the Treatment of Malignant Rhabdoid Tumor, Irish Association Cancer Research, Crowne Plaza Hotel, Santry, Dublin, 22nd February 2018, 2018
Poster; Presented; Non Peer Reviewed; Author Profile: DZISTRER

Coyle R, O'Sullivan M. & Zisterer DM, Inhibitor of Apoptosis Proteins as Targets for the Treatment of Malignant Rhabdoid Tumor, European Association for Cancer Research, Amsterdam Netherlands, 1 to 3 february 2018, 2018
Poster; Presented; Non Peer Reviewed; Author Profile: DZISTRER

Amet R., Previtali V., Browne P.V., Rozas I., McElligott A.M. & Zisterer D.M. , Novel anti-cancer therapeutics for multiple myeloma which target the STAT3 signalling pathway , European Association for Cancer Research, Amsterdam Netherlands, 1 to 3 february 2018, 2018
Poster; Presented; Non Peer Reviewed; Author Profile: DZISTRER

Amet R, Rozas I, McElligott AM, Browne P and Zisterer DM, Novel Anti-Cancer Therapeutics for Multiple Myeloma that target the STAT3 signalling pathway, Irish Association Cancer Research, Crowne Plaza Hotel, Santry, Dublin, 22nd February 2018, 2018
Poster; Presented; Non Peer Reviewed; Author Profile: DZISTRER

Pollock JK, Greene LM, Nathwani SM, Kinsella P, O'Boyle NM, Meegan MJ, Zisterer DM., Involvement of NF-kB in mediating the anti-tumour effects of combretastatins in T cells., Investigational new drugs, 36, (4), 2018, p523-535
Journal Article; Published; Peer Reviewed; Author Profiles: NIOBOYLE DZISTRER ; DOI

Ryan, EJ and Creagh, EM, Emerging Methods in Colorectal Cancer Screening, British Journal of Surgery, 105, (2), 2018, p16 - 18
Journal Article; Published; Peer Reviewed; Author Profile: ECREAGH; DOI

Petrasca A, Melo AM, Breen EP, Doherty DG, Human Vδ3+ γδ T cells induce maturation and IgM secretion by B cells, Immunology Letters, 196, 2018, 126-134
Journal Article; Published; Peer Reviewed; Author Profiles: PETRASAN DOHERTDE ; DOI; URL

Andrew J. Byrne, Sandra A. Bright, Darren Fayne, James P. McKeown, Thomas McCabe, Brendan Twamley, Clive Williams and Mary J. Meegan, Synthesis, Antiproliferative and Pro-Apoptotic Effects of Nitrostyrenes and Related Compounds in Burkitt's Lymphoma, Medicinal Chemistry, 14 , (1), 2018, p181 - 199
Journal Article; Published; Peer Reviewed; Author Profiles: MMEEGAN FAYNED

Djikic, T., Martí, Y., Spyrakis, F., (...), Schloss, P., Yelekci, K., Human dopamine transporter: the first implementation of a combined in silico/in vitro approach revealing the substrate and inhibitor specificities, Journal of Biomolecular Structure and Dynamics, 2018, p1-16
Journal Article; Published; Peer Reviewed; Author Profile: GDAVEY; DOI

Glover, L.E. and Crosby, D. and Thiruchelvam, U. and Harmon, C. and Chorcora, C.N. and Wingfield, M.B. and O'Farrelly, C., Uterine natural killer cell progenitor populations predict successful implantation in women with endometriosis-associated infertility, American Journal of Reproductive Immunology, 2018, pe12817-
Journal Article; Published; Peer Reviewed; Author Profile: OFARRECL; DOI; URL

Rolandi, E. and Cavedo, E. and Pievani, M. and Galluzzi, S. and Ribaldi, F. and Buckley, C. and Cunningham, C. and Guerra, U.P. and Musarra, M. and Morzenti, S. and Magnaldi, S. and Patassini, M. and Terragnoli, F. and Matascioli, L. and Franzoni, S. and Annoni, G. and Carnevali, L. and Bellelli, G. and Frisoni, G.B., Association of postoperative delirium with markers of neurodegeneration and brain amyloidosis: a pilot study, Neurobiology of Aging, 61, 2018, p93-101
Journal Article; Published; Peer Reviewed; Author Profile: CUNNINCO; DOI; URL

Mamad, O. and Islam, M.N. and Cunningham, C. and Tsanov, M., Differential response of hippocampal and prefrontal oscillations to systemic LPS application, Brain Research, 1681, 2018, p64-74
Journal Article; Published; Peer Reviewed; Author Profile: CUNNINCO; DOI; URL

David Finlay, Metabolic regulation of Immune responses., Institute Seminar Series, University of Lausanne, 21st November, 2018, Ping-Chih Ho
Invited Talk; Presented; Non Peer Reviewed; Author Profile: FINLAYD

David Finlay, What fuels Natural Killer Cell anti-tumour responses., Institute Seminar Series, University of Dundee, 28th Feburary, 2018
Invited Talk; Accepted; Non Peer Reviewed; Author Profile: FINLAYD

David Finlay, Metabolic regulation of NK cell anti-tumour responses, Natural Killer Cell Symposium 2018 - of the German Society for Immunology , Hamburg, Germany, 10th September, 2018, Keynote Speaker
Invited Talk; Presented; Non Peer Reviewed; Author Profile: FINLAYD

Zaiatz-Bittencourt, D.K. Finlay, C.M. Gardiner. , Canonical TGF signalling pathway represses human NK cell metabolism, Journal of Immunology, 200, (12), 2018, p3934 - 3941
Journal Article; Published; Peer Reviewed; Author Profiles: GARDINEC FINLAYD ; DOI

Dyck, L. and Lynch, L., Cancer, obesity and immunometabolism â€" Connecting the dots, Cancer Letters, 417, 2018, p11-20
Journal Article; Published; Peer Reviewed; Author Profile: LYNCHL3; DOI; URL

Saitoh S, Okano S, Nohara H, Nakano H, Shirasawa N, Naito A, Yamamoto M, Kelly VP, Takahashi K, Tanaka T, Nakajima M, Nakajima O., 5-aminolevulinic acid (ALA) deficiency causes impaired glucose tolerance and insulin resistance coincident with an attenuation of mitochondrial function in aged mice., PLoS One, 13, (1), 2018, p0189593-
Journal Article; Published; Peer Reviewed; Author Profile: KELLYVP; DOI

Longet S, Lundahl MLE, Lavelle EC., Targeted Strategies for Mucosal Vaccination., Bioconjugate Chemistry, 29, (3), 2018, p613 - 623
Journal Article; Published; Peer Reviewed; Author Profile: LAVELLEE; DOI

Oleszycka, E., McCluskey, S., Sharp, F.A., Muñoz-Wolf, N., Hams, E., Gorman, A.L., Fallon, P.G. and Lavelle EC., The vaccine adjuvant alum promotes IL-10 production that suppresses Th1 responses., European Journal of Immunology, 2018, 705-715
Journal Article; Published; Peer Reviewed; Author Profiles: PFALLON LAVELLEE ; DOI

Bowie, A.G., Self-RNA sentinels signal viral invasion news-and-views, Nature Immunology, 19, (1), 2018, p4-5
Journal Article; Published; Peer Reviewed; Author Profile: AGBOWIE; DOI; URL

Fazekas, B and Moreno-Olivera, A and Kelly, Y and O'Hara, P and Murray, S and Kennedy, A and Conlon, N and Scott, J and Melo, AM and Hickey, FB and Dooley, D and O'Brien, EC and Moran, S and Doherty, DG and Little, MA, Alterations in circulating lymphoid cell populations in systemic small vessel vasculitis are non-specific manifestations of renal injury, Clinical and experimental immunology, 191, (2), 2018, p180â€"188
Journal Article; Published; Peer Reviewed; Author Profiles: MLITTLE OBRIEE33 ; DOI; URL

*Galvin KC, *Conroy MJ, Doyle SL, Dunne MR, Fahey R, Foley E, O'Sullivan KE, Doherty DG, Geoghegan JG, Ravi N, O'Farrelly C, Reynolds JV, Lysaght J., Extratumoral PD-1 blockade does not perpetuate obesity-associated inflammation in esophageal adenocarcinoma., Cancer Letters, 418, 2018, p230-238
Journal Article; Published; Peer Reviewed; Author Profiles: MECONROY DUNNEM12 JLYSAGHT OFARRECL RAVIN ; DOI; URL

Mahon, O.R. and O'Hanlon, S. and Cunningham, C.C. and McCarthy, G.M. and Hobbs, C. and Nicolosi, V. and Kelly, D.J. and Dunne, A., Orthopaedic implant materials drive M1 macrophage polarization in a spleen tyrosine kinase- and mitogen-activated protein kinase-dependent manner, Acta Biomaterialia, 65, 2018, p426-435
Journal Article; Published; Peer Reviewed; Author Profiles: NICOLOV KELLYD9 AIDUNNE ; DOI; URL

Bourke NM, Napoletano S, Bannan C, Ahmed S, Bergin C, McKnight à , Stevenson NJ., Control of HIV infection by IFN-alpha: implications for latency and a cure., Cellular and molecular life sciences : CMLS, 75, (5), 2018, p775-783
Journal Article; Published; Peer Reviewed; Author Profiles: NBOURKE STEVENNJ ; DOI

O'Boyle, NM, Barrett, I, Greene, LM, Carr, M, Fayne, D, Twamley, B, Knox, AJS, Keely, NO, Zisterer, DM, Meegan, MJ, Lead Optimization of Benzoxepin-Type Selective Estrogen Receptor (ER) Modulators and Downregulators with Subtype-Specific ER-alpha and ER-beta Activity, Journal of Medicinal Chemistry, 61, (2), 2018, p514 - 534
Journal Article; Published; Peer Reviewed; Author Profiles: FAYNED MMEEGAN NIOBOYLE DZISTRER ; DOI; URL

Daniel G.W. Johnston, Christoph A. Thaiss, Raul Cabrera-Rubio, Michelle A. Williams, Paul D. Cotter, Eran Elinav, Luke A.J. O'Neill, Sinéad C. Corr, Loss of microRNA-21 influences the gut microbiota causing reduced susceptibility in a murine model of colitis., Journal of Crohns and Colitis, 12, (7), 2018, p835-
Journal Article; Published; Peer Reviewed; Author Profiles: CORRSC LAONEILL ; DOI