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Publications

Below is the list of peer and non peer publications from the School of Biochemistry and Immunology.

Show: AllPeer ReviewedNon Peer Reviewed
136 publications from 2016

Skovira J.W., Wu J., Matyas J.J., Kumar A., Hanscom M., Kabadi S.V., Fang R., Faden A.I., Cell cycle inhibition reduces inflammatory responses, neuronal loss, and cognitive deficits induced by hypobaria exposure following traumatic brain injury, Journal of Neuroinflammation, 13, (1), 2016
Journal Article; Published; Peer Reviewed; Author Profile: HANSCOMM; DOI

Waddell J., Hanscom M., Shalon Edwards N., McKenna M.C., McCarthy M.M., Sex differences in cell genesis, hippocampal volume and behavioral outcomes in a rat model of neonatal HI, Experimental Neurology, 275, 2016, p285 - 295, p285-295
Journal Article; Published; Peer Reviewed; Author Profile: HANSCOMM; DOI

Ryan, T.J. and Tonegawa, S., Erratum: Rehebbilitating Memory (Neuropsychopharmacology (2016) 41 (370-371) DOI: 10.1038/npp.2015.264), Neuropsychopharmacology, 41, (5), 2016, p1437
Journal Article; Published; Peer Reviewed; Author Profile: TRYAN6; DOI; URL

Lacey K.A, Geoghegan J.A, McLoughlin R.M, The role of staphylococcus aureus virulence factors in skin infection and their potential as vaccine antigens, Pathogens, 5, (1), 2016
Journal Article; Published; Peer Reviewed; Author Profile: MCLOUGRM; DOI; URL

Lecca, D., Nevin, D.K., Mulas, G., Casu, M.A., Diana, A., Rossi, D., Sacchetti, G., Fayne, D., Carta, A.R., Erratum: Corrigendum to "Neuroprotective and anti-inflammatory properties of a novel non-thiazolidinedione PPAR" agonist in vitro and in MPTP-treated mice" (Neuroscience (2015) 302 (23"35)(S030645221500367X)(10.1016/j.neuroscience.2015.04.026)), Neuroscience, 339, 2016
Journal Article; Published; Peer Reviewed; Author Profile: FAYNED

Innate immune receptors in, editor(s)Pablo Pelegrin and Francesco Di Virgilio , Nod Like Receptors, Springer, 2016, pp1-43 , [Muñoz-Wolf, N and Lavelle, E.C. ]
Book Chapter; Published; Peer Reviewed; Author Profile: LAVELLEE

Cunningham, C., Corr, E., McCarthy, G., Dunne, A, Phenotypic and Functional Characteristics of Exosomes Isolated from Human Osteoarthritis (OA) Synovial Fluid. , Arthritis Rheumatol. , 2016 ACR/ACHP Annual Meeting, Washington, 68 (suppl 10)., 2016
Conference Paper; Published; Peer Reviewed; Author Profile: AIDUNNE

Cunningham, C., Corr, E.M., McCarthy, G.M. and Dunne A, Intra-articular Basic Calcium Phosphate and Monosodium Urate Crystals Inhibit anti-osteoclastogenic Cytokine Signalling, Osteoarthritis and Cartilage, 24, 2016, p2141 - 2152
Journal Article; Published; Peer Reviewed; Author Profile: AIDUNNE; URL

Frank RA, Komiyama NH, Ryan TJ, Zhu F, O'Dell TJ, Grant SG., NMDA receptors are selectively partitioned into complexes and supercomplexes during synapse maturation., Nature communications, 7, 2016, p11264
Journal Article; Published; Peer Reviewed; Author Profile: TRYAN6; DOI

Poo MM, Pignatelli M, Ryan TJ, Tonegawa S, Bonhoeffer T, Martin KC, Rudenko A, Tsai LH, Tsien RW, Fishell G, Mullins C, Gonçalves JT, Shtrahman M, Johnston ST, Gage FH, Dan Y, Long J, Buzsáki G, Stevens C., What is memory? The present state of the engram., BMC biology, 14, 2016, p40
Journal Article; Published; Peer Reviewed; Author Profile: TRYAN6; DOI

Ryan TJ, Tonegawa S., Rehebbilitating Memory., Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 41, (1), 2016, p370-371
Journal Article; Published; Peer Reviewed; Author Profile: TRYAN6; DOI

Roy DS, Arons A, Mitchell TI, Pignatelli M, Ryan TJ, Tonegawa S., Memory retrieval by activating engram cells in mouse models of early Alzheimer's disease., Nature, 531, (7595), 2016, p508-512
Journal Article; Published; Peer Reviewed; Author Profile: TRYAN6; DOI

Svanborg C, Mok KH, Trulsson M, Mossberg A-K, Storm P, Ho CS, 'Biologically active complex and its preparation', European Patent Office, EP 2 643 010 B1, 2016, HAMLET Pharma AB
Patent; Granted; Peer Reviewed; Author Profile: MOK1

McGettrick AF, Corcoran SE, Barry PJG, McFarland J, Curtis AM, Franklin E, Corr SC, Mok KH, Cummins EP, Taylor CT, O'Neill LAJ, Nolan DP, The Trypanosoma brucei metabolite indolepyruvate decreases HIF-1 and glycolysis in macrophages as a mechanism of innate immune evasion, Proceedings of the National Academy of Sciences, U.S.A., 113, (48), 2016, pE7778 - E7787
Journal Article; Published; Peer Reviewed; Author Profiles: MOK1 DENOLAN LAONEILL ; URL

Kim KH, Yun S, Mok KH, Lee EK, Thermodynamic analysis of ANS binding to partially unfolded α-lactalbumin: correlation of endothermic to exothermic changeover with formation of authentic molten globules, Journal of Molecular Recognition, 29, 2016, p446 - 451
Journal Article; Published; Peer Reviewed; Author Profile: MOK1

Abbas SN, Mok KH, Rashid N, Xie Y, Ruether M, O'Brien J, Akhtar M, NMR studies on mechanism of isomerisation of fructose 6-phosphate to glucose 6-phosphate catalysed by phosphoglucose isomerase from Thermococcus kodakarensis, Bioorganic Chemistry, 66, 2016, p41 - 45
Journal Article; Published; Peer Reviewed; Author Profile: MOK1

Richard K. Porter, The Role of Mitochondrial Uncoupling Proteins in Thymus and Immune Cell Function, Visiting Professor, University of St. Andrews, Scotland, , April 2016, 2016
Invited Talk; Published; Peer Reviewed; Author Profile: RKPORTER

C.McKenna R.K.Porter, S.Waters and D.Kenny, Mitochondrial abundance and respiratory chain activities in muscle of cattle divergent in residual feed intake, European Federation of Animal Science (EAAP), Belfast UK, 29 Aug - 2 Sept 2016, Wageningen Academic Publisher, 2016
Meeting Abstract; Published; Peer Reviewed; Author Profile: RKPORTER

C.McKenna R.K.Porter, S.Waters and D.Kenny, Mitochondrial abundance and respiratory chain activities in muscle of cattle divergent in residual feed intake, EAAP, Belfast UK, 29 Aug - 2 Sept 2016, Wageningen Academic Publisher, 2016
Meeting Abstract; Published; Peer Reviewed; Author Profile: RKPORTER

Emma B. O ' Connor , Richard K. Porter , Patrick T. Walsh , A Role for Mitochondrial Uncoupling Protein 3 (UCP3) in T-cell function, Biochimica et Biophysica Acta (BBA) - Bioenergetics, European Bioenergetics Conference 2016 (EBEC 2016), Riva del garda, July 2-7, 2016, edited by Paolo Bernardi , Elsevier, 2016, pppe98-
Meeting Abstract; Published; Peer Reviewed; Author Profile: RKPORTER; URL

Mary F Rooney, Emmeline W Hill, Lisa M Katz and Richard K Porter , MSTN genotype variation affects skeletal muscle mitochondrial abundance and fibre composition in untrained Thoroughbred horses,, Biochimica et Biophysica Acta (BBA) - Bioenergetics, European Bioenergetics Conference 2016 (EBEC 2016), Riva del garda, July 2-7, 2016, edited by Paolo Bernardi , Volume 1857, 2016, ppp44-
Meeting Abstract; Published; Peer Reviewed; Author Profiles: ROONEYM4 RKPORTER ; DOI

Creagh, E.M., Inflammatory Caspase Expression during Colorectal Neoplasia, Irish Society of Gastroenterology, Summer Proceedings, Irish Society of Gastroenterology, Summer Meeting, Galway, Ireland., June 2016, edited by Michael Dineen, ISG , 2016
Oral Presentation; Presented; Peer Reviewed; Author Profile: ECREAGH

Creagh, E.M., Inflammatory Caspase Expression during Colorectal Neoplasia , 'Innovation in Diagnosis & Treatment of Colorectal Neoplasia', Centre for Colorectal Disease, St. Vincent's Hospital, 9th September, 2016, Prof. K Sheahan
Invited Talk; Presented; Peer Reviewed; Author Profile: ECREAGH

Narciandi, F. and Fernandez-Fuertes, B. and Khairulzaman, I. and Jahns, H. and King, D. and Finlay, E.K. and Mok, K.H. and Fair, S. and Lonergan, P. and O'Farrelly, C. and Meade, K.G., Sperm-coating beta-defensin 126 is a dissociation-resistant dimer produced by epididymal epithelium in the bovine reproductive tract, Biology of Reproduction, 95, (6), 2016, p1-9
Journal Article; Published; Peer Reviewed; Author Profile: OFARRECL; DOI; URL

Fernandez-Fuertes, B. and Narciandi, F. and O'Farrelly, C. and Kelly, A.K. and Fair, S. and Meade, K.G. and Lonergan, P., Cauda epididymis-specific beta-defensin 126 promotes sperm motility but not fertilizing ability in cattle, Biology of Reproduction, 95, (6), 2016, p1-12
Journal Article; Published; Peer Reviewed; Author Profile: OFARRECL; DOI; URL

Lynch, L. and Hogan, A.E. and Duquette, D. and Lester, C. and Banks, A. and LeClair, K. and Cohen, D.E. and Ghosh, A. and Lu, B. and Corrigan, M. and Stevanovic, D. and Maratos-Flier, E. and Drucker, D.J. and O'Shea, D. and Brenner, M., iNKT Cells Induce FGF21 for Thermogenesis and Are Required for Maximal Weight Loss in GLP1 Therapy, Cell Metabolism, 24, (3), 2016, p510-519
Journal Article; Published; Peer Reviewed; Author Profile: LYNCHL3; DOI; URL

Kohlgruber, A.C. and LaMarche, N.M. and Lynch, L., Adipose tissue at the nexus of systemic and cellular immunometabolism, Seminars in Immunology, 28, (5), 2016, p431-440
Journal Article; Published; Peer Reviewed; Author Profile: LYNCHL3; DOI; URL

Khalid, H. and Mukherjee, S.P. and O'Neill, L. and Byrne, H.J., Structural dependence of in vitro cytotoxicity, oxidative stress and uptake mechanisms of poly(propylene imine) dendritic nanoparticles, Journal of Applied Toxicology, 36, (3), 2016, p464-473
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Lavelle, E.C. and Tomar, J., Mucosal vaccines, adjuvants and delivery 2016 - A meetings management conference, Drugs of the Future, 41, (11), 2016, p689-695
Journal Article; Published; Peer Reviewed; Author Profile: LAVELLEE; DOI; URL

The Role of Inflammasomes in Adjuvant-Driven Humoral and Cellular Immune Responses in, editor(s)Virgil Schijns and Derek O'Hagan , Immunopotentiators in Modern Vaccines , 2016, pp23-42 , [Munoz-Wolf, N., McCluskey, S. and Lavelle, E.C.]
Book Chapter; Published; Peer Reviewed; Author Profile: LAVELLEE; DOI; URL

Medzhitov R, Belkaid Y, Davis M.M, Glimcher L, O'Neill L.A.J, Sallusto F, Immunology Gets out of the Box, Cell, 165, (4), 2016, p763 - 764
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

O'Neill L.A.J, Kishton R.J, Rathmell J, A guide to immunometabolism for immunologists, Nature Reviews Immunology, 16, (9), 2016, p553 - 565
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Corcoran S.E, O'Neill L.A.J, HIF1α and metabolic reprogramming in inflammation, Journal of Clinical Investigation, 126, (10), 2016, p3699 - 3707
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Mills E.L, Kelly B, Logan A, Costa A.S.H, Varma M, Bryant C.E, Tourlomousis P, DÀbritz J.H.M, Gottlieb E, Latorre I, Corr S.C, McManus G, Ryan D, Jacobs H.T, Szibor M, Xavier R.J, Braun T, Frezza C, Murphy M.P, O'Neill L.A, Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages, Cell, 167, (2), 2016, p457 - 470.e13
Journal Article; Published; Peer Reviewed; Author Profiles: CORRSC LAONEILL ; DOI; URL

O'Neill L.A.J, A Metabolic Roadblock in Inflammatory Macrophages, Cell Reports, 17, (3), 2016, p625 - 626
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Brady G, Boggan L, Bowie A, O'Neill L.A.J, Erratum: Schlafen-1 causes a cell cycle arrest by inhibiting induction of cyclin D1 (The Journal of Biological Chemistry (2005) 280 (30723-30734) DOI: 10.1074/jbc.M500435200), Journal of Biological Chemistry, 291, (48), 2016, p25278-
Journal Article; Published; Peer Reviewed; Author Profiles: LAONEILL BRADYG1 AGBOWIE ; DOI; URL

Gray P, Dunne A, Brikos C, Jefferies C.A, Doyle S.L, O'Neill L.A.J, Erratum: MyD88 adapter-like (Mal) is phosphorylated by Bruton's tyrosine kinase during TLR2 and TLR4 signal transduction (Journal of Biological Chemistry (2006) 281 (10489-10495) DOI: 10.1074/jbc.M508892200), Journal of Biological Chemistry, 291, (50), 2016, p26240-
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Arts R.J.W, Novakovic B, ter Horst R, Carvalho A, Bekkering S, Lachmandas E, Rodrigues F, Silvestre R, Cheng S.-C, Wang S.-Y, Habibi E, Gonçalves L.G, Mesquita I, Cunha C, van Laarhoven A, van de Veerdonk F.L, Williams D.L, van der Meer J.W.M, Logie C, O'Neill L.A, Dinarello C.A, Riksen N.P, van Crevel R, Clish C, Notebaart R.A, Joosten L.A.B, Stunnenberg H.G, Xavier R.J, Netea M.G, Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity, Cell Metabolism, 24, (6), 2016, p807 - 819
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Basiorka A.A, McGraw K.L, Eksioglu E.A, Chen X, Johnson J, Zhang L, Zhang Q, Irvine B.A, Cluzeau T, Sallman D.A, Padron E, Komrokji R, Sokol L, Coll R.C, Robertson A.A.B, Cooper M.A, Cleveland J.L, O'Neill L.A, Wei S, List A.F, The NLRP3 inflammasome functions as a driver of the myelodysplastic syndrome phenotype, Blood, 128, (25), 2016, p2960 - 2975
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Colm Cunningham, Neurosciences in Intensive Care Symposium, Pasteur institute, Paris, June, 2016
Invited Talk; Presented; Non Peer Reviewed; Author Profile: CUNNINCO

Colm Cunningham, Immunology research series, University of Cambridge, October, 2016
Invited Talk; Presented; Non Peer Reviewed; Author Profile: CUNNINCO

Colm Cunningham, American Delirium Society Annual Meeting, Nashville, June, 2016
Invited Talk; Presented; Non Peer Reviewed; Author Profile: CUNNINCO

Deac OM, Mills JL, Gardiner CM, Shane B, Quinn L, Midttun O, McCann A, Meyer K, Ueland PM, Fan R, Lu Z, Brody LC, Molloy AM, Serum Immune System Biomarkers Neopterin and Interleukin-10 Are Strongly Related to Tryptophan Metabolism in Healthy Young Adults, J Nutr, 146, (9), 2016, p1801 - 1806
Journal Article; Published; Peer Reviewed; Author Profiles: AMOLLOY GARDINEC ; DOI

Fischer J, Weber AN, Böhm S, Dickhöfer S, El Maadidi S, Deichsel D, Knop V, Klinker H, Möller B, Rasenack J, Wang L, Sharma M, Hinrichsen H, Spengler U, Buggisch P, Sarrazin C, Pawlita M, Waterboer T, Wiese M, Probst-Müller E, Malinverni R, Bochud PY, Gardiner CM, O'Farrelly C, Berg T., Sex-specific effects of TLR9 promoter variants on spontaneous clearance of HCV infection., Gut, 2016, pdoi: 10.1136/gutjnl-2015-31023
Journal Article; Published; Peer Reviewed; Author Profile: GARDINEC; DOI; URL

David Finlay, Glucose represses Dendritic Cell-induced T cell responses, Institute Seminar, Medical University of Vienna, Institute of Medical GeneticsUniversity of , 6th December, 2016, Thomas Weichhart, PhD
Invited Talk; Presented; Non Peer Reviewed; Author Profile: FINLAYD

Gleeson, L.E., Sheedy, F.J., Metabolic reprogramming & inflammation: Fuelling the host response to pathogens, Seminars in Immunology, 28, (5), 2016, p450-468
Journal Article; Published; Peer Reviewed; Author Profile: FSHEEDY

Sensing the Environment Through Sestrins: Implications for Cellular Metabolism. in, editor(s)Kwan W. Jeon and Lorenzo Galluzzi , International Review of Cell and Molecular Biology, Elsevier, 2016, pp1 - 24, [Parmigiani A, Budanov AV]
Book Chapter; Published; Peer Reviewed; Author Profile: BUDANOVA; DOI

Ding B, Parmigiani A, Divakaruni AS, Archer K, Murphy AN, Budanov AV, Sestrin2 is induced by glucose starvation via the unfolded protein response and protects cells from non-canonical necroptotic cell death., Scientific Reports, 6, (22538), 2016, p14
Journal Article; Published; Peer Reviewed; Author Profile: BUDANOVA; DOI

Tsilioni I, Filippidis AS, Kerenidi T, Budanov AV, Zarogiannis SG, Gourgoulianis KI, Sestrin-2 is significantly increased in malignant pleural effusions due to lung cancer and is potentially secreted by pleural mesothelial cells., Clinical Biochemistry, 49, (9), 2016, p726 - 728
Journal Article; Published; Peer Reviewed; Author Profile: BUDANOVA; DOI

Host pathogen interactions in, editor(s)Greg A Somerville , Staphylococcus: Genetics and Physiology, Caister Academic Press, 2016, ppvii+390 , [Aisling F Brown, Rachel M McLoughlin]
Book Chapter; Published; Peer Reviewed; Author Profile: MCLOUGRM; DOI

Coughlan AM, Harmon C, Whelan S, O'Brien EC, O'Reilly VP, Crotty P, Kelly P, Ryan M, Hickey FB, O'Farrelly C, Little MA., Myeloid Engraftment in Humanized Mice: Impact of Granulocyte-Colony Stimulating Factor Treatment and Transgenic Mouse Strain., Stem Cells and Development, 25, (7), 2016, p530 - 541
Journal Article; Published; Peer Reviewed; Author Profile: OBRIEE33; DOI; URL

O'Reilly VP, Wong L, Kennedy C, Elliot LA, O'Meachair S, Coughlan AM, O'Brien EC, Ryan MM, Sandoval D, Connolly E, Dekkema GJ, Lau J, Abdulahad WH, Sanders JS, Heeringa P, Buckley C, O'Brien C, Finn S, Cohen CD, Lindemeyer MT, Hickey FB, O'Hara PV, Feighery C, Moran SM, Mellotte G, Clarkson MR, Dorman AJ, Murray PT, Little MA., Urinary Soluble CD163 in Active Renal Vasculitis., Journal of the American Society of Nephrology, 27, (9), 2016, p2906 - 2916
Journal Article; Published; Peer Reviewed; Author Profiles: MLITTLE MELLOTTG FINNS OBRIEE33 ; DOI; URL

Olieric V, Weinert T, Finke A.D, Anders C, Li D, Olieric N, Borca C.N, Steinmetz M.O, Caffrey M, Jinek M, Wang M, Data-collection strategy for challenging native SAD phasing, Acta Crystallographica Section D: Structural Biology, 72, (3), 2016, p421 - 429
Journal Article; Published; Peer Reviewed; Author Profile: MCAFFRE; DOI; URL

Huang C.Y, Olieric V, Ma P, Howe N, Vogeley L, Liu X, Warshamanage R, Weinert T, Panepucci E, Kobilka B, Diederichs K, Wang M, Caffrey M, In meso in situ serial X-ray crystallography of soluble and membrane proteins at cryogenic temperatures, Acta crystallographica. Section D, Structural biology, 72, 2016, p93 - 112
Journal Article; Published; Peer Reviewed; Author Profile: MCAFFRE; DOI; URL

Wojdyla J.A, Panepucci E, Martiel I, Ebner S, Huang C.-Y, Caffrey M, Bunk O, Wang M, Fast two-dimensional grid and transmission X-ray microscopy scanning methods for visualizing and characterizing protein crystals, Journal of Applied Crystallography, 49, 2016, p944 - 952
Journal Article; Published; Peer Reviewed; Author Profile: MCAFFRE; DOI; URL

Vogeley L, El Arnaout T, Bailey J, Stansfeld P.J, Boland C, Caffrey M, Structural basis of lipoprotein signal peptidase II action and inhibition by the antibiotic globomycin, Science, 351, (6275), 2016, p876 - 880
Journal Article; Published; Peer Reviewed; Author Profile: MCAFFRE; DOI; URL

Zhou X.E, Gao X, Barty A, Kang Y, He Y, Liu W, Ishchenko A, White T.A, Yefanov O, Han G.W, Xu Q, De Waal P.W, Suino-Powell K.M, Boutet S, Williams G.J, Wang M, Li D, Caffrey M, Chapman H.N, Spence J.C.H, Fromme P, Weierstall U, Stevens R.C, Cherezov V, Melcher K, Xu H.E, X-ray laser diffraction for structure determination of the rhodopsin-arrestin complex, Scientific Data, 3, 2016, p21-
Journal Article; Published; Peer Reviewed; Author Profile: MCAFFRE; DOI; URL

Rues R.-B, Henrich E, Boland C, Caffrey M, Bernhard F, Cell-free production of membrane proteins in escherichia coli lysates for functional and structural studies, Protocol Heterologous Expression of Membrane Proteins, 1432, 2016, p1-21
Journal Article; Published; Peer Reviewed; Author Profile: MCAFFRE; DOI; URL

Conroy M.J, Fitzgerald V, Doyle S.L, Channon S, Useckaite Z, Gilmartin N, O†Farrelly C, Ravi N, Reynolds J.V, Lysaght J, The microenvironment of visceral adipose tissue and liver alter natural killer cell viability and function, Journal of Leukocyte Biology, 100, (6), 2016, p1435 - 1442
Journal Article; Published; Peer Reviewed; Author Profiles: JLYSAGHT RAVIN OFARRECL REYNOLJV ; DOI; URL

Mulcahy M.E, McLoughlin R.M, Staphylococcus aureus and influenza a virus: Partners in coinfection, mBio, 7, (6), 2016, e02068-16
Journal Article; Published; Peer Reviewed; Author Profile: MCLOUGRM; DOI; URL

Lalor S.J, McLoughlin R.M, Memory γÎ" T Cellsâ€"Newly Appreciated Protagonists in Infection and Immunity, Trends in Immunology, 37, (10), 2016, p690 - 702
Journal Article; Published; Peer Reviewed; Author Profiles: MCLOUGRM LALORST ; DOI; URL

Mulcahy M.E, McLoughlin R.M, Hostâ€"Bacterial Crosstalk Determines Staphylococcus aureus Nasal Colonization, Trends in Microbiology, 24, (11), 2016, p872 - 886
Journal Article; Published; Peer Reviewed; Author Profile: MCLOUGRM; DOI; URL

Stojkovic B, McLoughlin R.M, Meade K.G, In vivo relevance of polymorphic Interleukin 8 promoter haplotype for the systemic immune response to LPS in Holstein-Friesian calves, Veterinary Immunology and Immunopathology, 182, 2016, p1 - 10
Journal Article; Published; Peer Reviewed; Author Profile: MCLOUGRM; DOI; URL

Williams JM, Bezak T, Das M, Ning Z, Lucking EF, Kelly VP, Harrison P, Young P, O'Connell MJ, Dockery P, O'Halloran KD, Moore T , Psg22 null mouse embryos develop normally under normoxic and hypoxic conditions of pregnancy., Science Matters, 10, (19185), 2016
Journal Article; Published; Peer Reviewed; Author Profile: KELLYVP; DOI; URL

Exley M.A, Tsokos G.C, Mills K.H.G, Elewaut D, Mulhearn B, What rheumatologists need to know about innate lymphocytes, Nature Reviews Rheumatology, 12, (11), 2016, 2016 Nov;12(11):658-668. doi:
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI; URL

Hayes J.M, Wormald M.R, Rudd P.M, Davey G.P, Fc gamma receptors: Glycobiology and therapeutic prospects, Journal of Inflammation Research, 9, 2016, p209 - 219
Journal Article; Published; Peer Reviewed; Author Profile: GDAVEY; DOI; URL

Pandiyan P, Lavelle E.C, Editorial: Immune cells in the mucosa, Frontiers in Immunology, 7, (DEC), 2016, p00657-
Journal Article; Published; Peer Reviewed; Author Profile: LAVELLEE; DOI; URL

Al-Ani B, Fitzpatrick M, Al-Nuaimi H, Coughlan A.M, Hickey F.B, Pusey C.D, Savage C, Benton C.M, O'Brien E.C, O'Toole D, Mok K.H, Young S.P, Little M.A, Changes in urinary metabolomic profile during relapsing renal vasculitis, Scientific Reports, 6, 2016, 38074 -
Journal Article; Published; Peer Reviewed; Author Profiles: OBRIEE33 MLITTLE MOK1 ; DOI; URL

Greene L.M, Butini S, Campiani G, Williams D.C, Zisterer D.M, Pre-clinical evaluation of a novel class of anti-cancer agents, the Pyrrolo-1, 5-benzoxazepines, Journal of Cancer, 7, (15), 2016, p2367 - 2377
Journal Article; Published; Peer Reviewed; Author Profile: DZISTRER; DOI; URL

Johnson G.P, Lloyd A.T, O'Farrelly C, Meade K.G, Fair S, Comparative genomic identification and expression profiling of a novel β-defensin gene cluster in the equine reproductive tract, Reproduction, Fertility and Development, 28, (10), 2016, p1499 - 1508
Journal Article; Published; Peer Reviewed; Author Profile: OFARRECL; DOI; URL

Harmon C, Sanchez-Fueyo A, O'Farrelly C, Houlihan D.D, Natural Killer Cells and Liver Transplantation: Orchestrators of Rejection or Tolerance?, American Journal of Transplantation, 16, (3), 2016, p751 - 757
Journal Article; Published; Peer Reviewed; Author Profile: OFARRECL; DOI; URL

Coughlan A.M, Harmon C, Whelan S, O'Brien E.C, O'Reilly V.P, Crotty P, Kelly P, Ryan M, Hickey F.B, O'Farrelly C, Little M.A, Myeloid engraftment in humanized mice: Impact of granulocyte-colony stimulating factor treatment and transgenic mouse strain, Stem Cells and Development, 25, (7), 2016, p530 - 541
Journal Article; Published; Peer Reviewed; Author Profiles: MLITTLE OFARRECL ; DOI; URL

Thiruchelvam U, Wingfield M, O'Farrelly C, Increased uNK Progenitor Cells in Women With Endometriosis and Infertility are Associated With Low Levels of Endometrial Stem Cell Factor, American Journal of Reproductive Immunology, 75, (4), 2016, p493 - 502
Journal Article; Published; Peer Reviewed; Author Profile: OFARRECL; DOI; URL

Fischer J, Weber A.N.R, Bohm S, Dickhöfer S, El Maadidi S, Deichsel D, Knop V, Klinker H, Möller B, Rasenack J, Wang L, Sharma M, Hinrichsen H, Spengler U, Buggisch P, Sarrazin C, Pawlita M, Waterboer T, Wiese M, Probst-MÃ"ller E, Malinverni R, Bochud P.-Y, Gardiner C, O'Farrelly C, Berg T, Sex-specific effects of TLR9 promoter variants on spontaneous clearance of HCV infection, Gut, 2016
Journal Article; In_press; Peer Reviewed; Author Profile: OFARRECL; DOI; URL

Robinson M.W, Harmon C, O'Farrelly C, Liver immunology and its role in inflammation and homeostasis, Cellular and Molecular Immunology, 13, (3), 2016, p267 - 276
Journal Article; Published; Peer Reviewed; Author Profile: OFARRECL; DOI; URL

Conroy M.J, Galvin K.C, Kavanagh M.E, Mongan A.M, Doyle S.L, Gilmartin N, O'Farrelly C, Reynolds J.V, Lysaght J, CCR1 antagonism attenuates T cell trafficking to omentum and liver in obesity-associated cancer, Immunology and Cell Biology, 94, (6), 2016, p531 - 537
Journal Article; Published; Peer Reviewed; Author Profiles: JLYSAGHT OFARRECL REYNOLJV MECONROY ; DOI; URL

Harmon C, Robinson M.W, Fahey R, Whelan S, Houlihan D.D, Geoghegan J, O'Farrelly C, Tissue-resident Eomeshi T-betlo CD56bright NK cells with reduced proinflammatory potential are enriched in the adult human liver, European Journal of Immunology, 46, (9), 2016, p2111 - 2120
Journal Article; Published; Peer Reviewed; Author Profile: OFARRECL; DOI; URL

Doherty R, Whiston R, Cormican P, Finlay E.K, Couldrey C, Brady C, O'Farrelly C, Meade K.G, The CD4 + T cell methylome contributes to a distinct CD4 + T cell transcriptional signature in Mycobacterium bovis-infected cattle, Scientific Reports, 6, 2016, p31014
Journal Article; Published; Peer Reviewed; Author Profile: OFARRECL; DOI; URL

Rush G, O'Donovan A, Nagle L, Conway C, McCrohan A, O'Farrelly C, Lucey J.V, Malone K.M, Alteration of immune markers in a group of melancholic depressed patients and their response to electroconvulsive therapy, Journal of Affective Disorders, 205, 2016, p60 - 68
Journal Article; Published; Peer Reviewed; Author Profile: OFARRECL; DOI; URL

Kelly A, Robinson M.W, Roche G, Biron C.A, O'Farrelly C, Ryan E.J, Immune Cell Profiling of IFN-λ Response Shows pDCs Express Highest Level of IFN-λR1 and Are Directly Responsive via the JAK-STAT Pathway, Journal of Interferon and Cytokine Research, 36, (12), 2016, p671 - 680
Journal Article; Published; Peer Reviewed; Author Profile: OFARRECL; DOI; URL

Shirey, K.A, Lai, W., Pletneva, L.M., Patel, M., Pang, C., Kurt-Jones, E., Lipsky, M., Roger, T., Calandra, T., Tracey, K., Al Abed, Y., Bowie, A.G., Fasano, A., Dinarello, C., Gusovsky, F., Blanco, J.C.G., and Vogel S.N., Novel Strategies for Targeting Innate Immune Responses to Influenza , Mucosal Immunology , 9, 2016, p1173 - 1182
Journal Article; Published; Peer Reviewed; Author Profile: AGBOWIE; DOI

Dyck L, Wilk M.M, Raverdeau M, Misiak A, Boon L, Mills K.H.G, Anti-PD-1 inhibits Foxp3+ Treg cell conversion and unleashes intratumoural effector T cells thereby enhancing the efficacy of a cancer vaccine in a mouse model, Cancer Immunol Immunother , 65, 2016, p1491-
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI; URL

Mulcahy M.E, Leech J.M, Renauld J.-C, Mills K.H.G, McLoughlin R.M, Interleukin-22 regulates antimicrobial peptide expression and keratinocyte differentiation to control Staphylococcus aureus colonization of the nasal mucosa, Mucosal Immunology, 9, (6), 2016, p1429 - 1441
Journal Article; Published; Peer Reviewed; Author Profiles: MCLOUGRM MILLSK ; DOI; URL

Saadatian-Elahi M, Plotkin S, Mills K.H.G, Halperin S.A, McIntyre P.B, Picot V, Louis J, Johnson D.R, Pertussis: Biology, epidemiology and prevention, Vaccine, 34, (48), 2016, p5819 - 5826
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI; URL

Ouimet, M., Koster, S., Sakowski, E., Ramkhelawon, B., Van Solingen, C., Oldebeken, S., Karunakaran, D., Portal-Celhay, C., Sheedy, F.J., Ray, T.D., Cecchini, K., Zamore, P.D., Rayner, K.J., Marcel, Y.L., Philips, J.A., Moore, K.J., Mycobacterium tuberculosis induces the MIR-33 locus to reprogram autophagy and host lipid metabolism, Nature Immunology, 17, (6), 2016, p677-686
Journal Article; Published; Peer Reviewed; Author Profile: FSHEEDY

Greene LM, Nathwani SM, Zisterer DM., Inhibition of γ-secretase activity synergistically enhances tumour necrosis factor-related apoptosis-inducing ligand induced apoptosis in T-cell acute lymphoblastic leukemia cells via upregulation of death receptor 5., Oncology Letters, 12, (4), 2016, p2900 - 2905
Journal Article; Published; Peer Reviewed; Author Profile: DZISTRER; DOI

Carr M, Knox AJ, Lloyd DG, Zisterer DM, Meegan MJ., Development of the β-lactam type molecular scaffold for selective estrogen receptor α modulator action: synthesis and cytotoxic effects in MCF-7 breast cancer cells., Journal of Enzyme Inhibition and Medicinal Chemistry, 31, 2016, p117-130
Journal Article; Published; Peer Reviewed; Author Profile: DZISTRER; DOI

Flood B, Oficjalska K, Fay J, O'Grady A, Ryan EJ, Doherty GA, Kay E and Creagh EM. , Epithelial expression of inflammatory caspases-4 and -5 is specific to malignancy in colorectal cancer patients. , Gasteroenterology, Digestive Diseases Week (DDW), San Diego, CA, 19-24 May 2016, 150, (4), American Gastroenterology Association (AGA), 2016, ppS616-S617
Conference Paper; Published; Peer Reviewed; Author Profile: ECREAGH; DOI

Brindisi M, Maramai S, Brogi S, Fanigliulo E, Butini S, Guarino E, Casagni A, Lamponi S, Bonechi C, Nathwani SM, Finetti F, Ragonese F, Arcidiacono P, Campiglia P, Valenti S, Novellino E, Spaccapelo R, Morbidelli L, Zisterer DM, Williams CD, Donati A, Baldari C, Campiani G, Ulivieri C, Gemma S., Development of novel cyclic peptides as pro-apoptotic agents., European Journal of Medicinal Chemistry, 117, 2016, p301 - 320
Journal Article; Published; Peer Reviewed; Author Profile: DZISTRER; DOI

Greene TF, Wang S, Greene LM, Nathwani SM, Pollock JK, Malebari AM, McCabe T, Twamley B, O'Boyle NM, Zisterer DM, Meegan MJ, Synthesis and Biochemical Evaluation of 3-Phenoxy-1,4-diarylazetidin-2-ones as Tubulin-Targeting Antitumor Agents., Journal of Medicinal Chemistry, 59, (1), 2016, p90 - 113
Journal Article; Published; Peer Reviewed; Author Profiles: DZISTRER NIOBOYLE MMEEGAN ; DOI; URL

Neuroinflammatory Disorders in, editor(s)Orla Hardiman, Colin P. Doherty, Marwa Elami, Peter Bede , Neurodegenerative Disorders, Springer International Publishing, 2016, pp269 - 287, [Costelloe C, Fletcher JM, Fitzgerald D. Neuroinflammatory Disorders. (In Neurodegenerative Disorders).]
Book Chapter; Published; Peer Reviewed; Author Profiles: FLETCHJ SHUTCHIN

Basdeo SA, Kelly S, O'Connell K, Tubridy N, McGuigan C, Fletcher JM, Increased expression of Tbet in CD4+ T cells from clinically isolated syndrome patients at high risk of conversion to clinically definite MS. , Springer Plus, 5, 2016, p779-
Journal Article; Published; Peer Reviewed; Author Profile: FLETCHJ; URL

Dunne M, Ryan C, Tosetto M, Nolan B, Geraghty R, Winter DC, O'Connell R, Hyland J, Doherty GA, Sheahan K, Ryan EJ, Fletcher JM., Enrichment of inflammatory IL-17 and TNF-α secreting CD4+ T cells within colorectal tumours despite the presence of elevated CD39+ T regulatory cells and increased expression of the immune checkpoint molecule, PD-1., Frontiers in Oncology, 6, 2016, p50-
Journal Article; Published; Peer Reviewed; Author Profile: FLETCHJ; URL

Muñoz-Wolf N, Lavelle EC., Innate Immune Receptors., Methods Mol Biol., 1417, 2016, p1 - 43
Journal Article; Published; Peer Reviewed; Author Profile: LAVELLEE; DOI

McGettrick AF, Corcoran SE, Barry PJ, McFarland J, Crès C, Curtis AM, Franklin E, Corr SC, Mok KH, Cummins EP, Taylor CT, O'Neill LA, Nolan DP, Trypanosoma brucei metabolite indolepyruvate decreases HIF-1α and glycolysis in macrophages as a mechanism of innate immune evasion., Proc Natl Acad Sci U S A. , 113, (48), 2016, E7778-E7787
Journal Article; Published; Peer Reviewed; Author Profiles: DENOLAN LAONEILL CORRSC ; DOI

Davitt, C.J.H., McNeela, E.A., Longet, S., Tobias, J., Aversa, V., McEntee, C.P., Rosa, M., Coulter, I.S., Holmgren, J., Lavelle, E.C., A novel adjuvanted capsule based strategy for oral vaccination against infectious diarrhoeal pathogens, Journal of Controlled Release, 233, 2016, p162-173
Journal Article; Published; Peer Reviewed; Author Profile: LAVELLEE; DOI

Hughes, C.S., Colhoun, L.M., Bains, B.K., Kilgour, J.D., Burden, R.E., Burrows, J.F., Lavelle, E.C., Gilmore, B.F., Scott, C.J., Extracellular cathepsin S and intracellular caspase 1 activation are surrogate biomarkers of particulate-induced lysosomal disruption in macrophages, Particle and Fibre Toxicology, 13, (1), 2016, p19-
Journal Article; Published; Peer Reviewed; Author Profile: LAVELLEE; DOI

Schwartz, C., O'Grady, K., Lavelle, E.C., Fallon, P.G., Interleukin 33: An innate alarm for adaptive responses beyond Th2 immunity-emerging roles in obesity, intestinal inflammation, and cancer, European Journal of Immunology, 46, (5), 2016, p1091-1100
Journal Article; Published; Peer Reviewed; Author Profiles: LAVELLEE PFALLON ; DOI

Lebre, F., Hearnden, C.H., Lavelle, E.C., Modulation of Immune Responses by Particulate Materials, Advanced Materials, 2016, 5525-5541
Journal Article; Published; Peer Reviewed; Author Profile: LAVELLEE; DOI

Carroll, E.C., Jin, L., Mori, A., Muñoz-Wolf, N., Oleszycka, E., Moran, H.B.T., Mansouri, S., McEntee, C.P., Lambe, E., Agger, E.M., Andersen, P., Cunningham, C., Hertzog, P., Fitzgerald, K.A., Bowie, A.G., Lavelle, E.C., The Vaccine Adjuvant Chitosan Promotes Cellular Immunity via DNA Sensor cGAS-STING-Dependent Induction of Type I Interferons, Immunity, 44, (3), 2016, p597 - 608
Journal Article; Published; Peer Reviewed; Author Profiles: CUNNINCO AGBOWIE LAVELLEE ; DOI

Oleszycka, E., Moran, H.B.T., Tynan, G.A., Hearnden, C.H., Coutts, G., Campbell, M., Allan, S.M., Scott, C.J. and Lavelle, E.C. , IL-1α and inflammasome-independent IL-1β promote neutrophil infiltration following alum vaccination. , FEBS Journal, 283, (1), 2016, p9 - 24
Journal Article; Published; Peer Reviewed; Author Profiles: LAVELLEE CAMPBEM2 ; DOI

Walls J, Sinclair L, Finlay D, Nutrient sensing, signal transduction and immune responses., Seminars in Immunology, 28, (5), 2016, p396-407
Review Article; Published; Peer Reviewed; Author Profile: FINLAYD; DOI

Chintapalli R, Murray MJ, Murray JT, Heat Inactivation of Garlic (Allium sativum) Extract Abrogates Growth Inhibition of HeLa Cells., Nutrition and cancer, 2016, p1-9
Journal Article; Published; Peer Reviewed; Author Profile: JMURRAY6; DOI

Keating SE, Zaiatz-Bittencourt V, Loftus RM, Keane C, Brennan K, Finlay DK, Gardiner CM., Metabolic Reprogramming Supports IFN-γ Production by CD56bright NK Cells., Journal of Immunology, 196, (6), 2016, p2552 - 2560
Journal Article; Published; Peer Reviewed; Author Profile: FINLAYD; DOI; URL

Viel S, Marçais A, Guimaraes FS, Loftus R, Rabilloud J, Grau M, Degouve S, Djebali S, Sanlaville A, Charrier E, Bienvenu J, Marie JC, Caux C, Marvel J, Town L, Huntington ND, Bartholin L, Finlay D, Smyth MJ, Walzer T, TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway., Science Signalling, 9, 2016, pra19-
Journal Article; Published; Peer Reviewed; Author Profile: FINLAYD; DOI

Assmann N, Finlay DK., Metabolic regulation of immune responses: therapeutic opportunities., Journal of Clinical Investigation, 126, (6), 2016, p2031 - 2039
Review Article; Published; Peer Reviewed; Author Profile: FINLAYD; URL

Mahony R, Ahmed S, Diskin C, Stevenson NJ, SOCS3 revisited: a broad regulator of disease, ready for therapeutic use?, Cellular and Molecular Life Sciences, 73, (17), 2016, p3323 - 3336
Review Article; Published; Peer Reviewed; Author Profile: STEVENNJ

Kahvedzic -Seljubac A, Nathwani S.-M, Zisterer D.M, Rozas I, Isouronium and N-hydroxyguanidinium derivatives as Cell growth inhibitors: A comparative study, European Journal of Medicinal Chemistry, 117, 2016, p269 - 282
Journal Article; Published; Peer Reviewed; Author Profiles: ROZASI DZISTRER ; DOI; URL

Nathwani SM, Greene LM, Butini S, Campiani G, Williams DC, Samali A, Szegezdi E, Zisterer DM, The pyrrolo-1,5-benzoxazepine, PBOX-15, enhances TRAIL"induced apoptosis by upregulation of DR5 and downregulation of core cell survival proteins in acute lymphoblastic leukaemia cells., International journal of oncology, 49, (1), 2016, p74-88
Journal Article; Published; Peer Reviewed; Author Profiles: DZISTRER DWILLIMS ; DOI

Lennon JC, Butini S, Campiani G, O'Meara A, Williams DC, Zisterer DM, Involvement of AMP-activated protein kinase in mediating pyrrolo-1,5-benzoxazepine-induced apoptosis in neuroblastoma cells., Investigational new drugs, 34, (5), 2016, p663-76
Journal Article; Published; Peer Reviewed; Author Profiles: DZISTRER DWILLIMS ; DOI

Kelly PM, Bright SA, Fayne D, Pollock JK, Zisterer DM, Williams DC, Meegan MJ, Synthesis, antiproliferative and pro-apoptotic activity of 2-phenylindoles., Bioorganic & medicinal chemistry, 24, (18), 2016, p4075-99
Journal Article; Published; Peer Reviewed; Author Profiles: DZISTRER FAYNED DWILLIMS ; DOI

Mills E.L, O'Neill L.A, Reprogramming mitochondrial metabolism in macrophages as an anti-inflammatory signal, European Journal of Immunology, 46, (1), 2016, p13 - 21
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

O'Neill L.A.J, Pearce E.J, Immunometabolism governs dendritic cell and macrophage function, Journal of Experimental Medicine, 213, (1), 2016, p15 - 23
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Joosten L.A.B, Abdollahi-Roodsaz S, Dinarello C.A, O'Neill L, Netea M.G, Toll-like receptors and chronic inflammation in rheumatic diseases: New developments, Nature Reviews Rheumatology, 12, (6), 2016, p344 - 357
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Arbore G, West E.E, Spolski R, Robertson A.A.B, Klos A, Rheinheimer C, Dutow P, Woodruff T.M, Yu Z.X, O'Neill L.A, Coll R.C, Sher A, Leonard W.J, Köhl J, Monk P, Cooper M.A, Arno M, Afzali B, Lachmann H.J, Cope A.P, Mayer-Barber K.D, Kemper C, T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4+ T cells, Science, 352, (6292), 2016
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Gardiner C.M, Mills K.H.G, The cells that mediate innate immune memory and their functional significance in inflammatory and infectious diseases, Seminars in Immunology, 28, (4), 2016, p343-350
Journal Article; Published; Peer Reviewed; Author Profiles: MILLSK GARDINEC ; DOI; URL

Netea M.G, Joosten L.A.B, Latz E, Mills K.H.G, Natoli G, Stunnenberg H.G, O'Neill L.A.J, Xavier R.J, Trained immunity: A program of innate immune memory in health and disease, Science, 352, (6284), 2016, p427-
Journal Article; Published; Peer Reviewed; Author Profiles: LAONEILL MILLSK ; DOI; URL

Lee J.P.W, Foote A, Fan H, Peral de Castro C, Lang T, Jones S.A, Gavrilescu N, Mills K.H.G, Leech M, Morand E.F, Harris J, Loss of autophagy enhances MIF/macrophage migration inhibitory factor release by macrophages, Autophagy, 12, (6), 2016, p907 - 916
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI; URL

Raverdeau M, Breen C.J, Misiak A, Mills K.H.G, Retinoic acid suppresses IL-17 production and pathogenic activity of γΎ T cells in CNS autoimmunity, Immunology and Cell Biology, 94, (8), 2016, p763 - 773
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI; URL

McDonald AG, Hayes JM, Davey GP, Metabolic flux control in glycosylation., Current opinion in structural biology, 40, 2016, p97-103
Journal Article; Published; Peer Reviewed; Author Profile: GDAVEY; DOI

Basdeo S.A, Campbell N.K, Sullivan L.M, Flood B, Creagh E.M, Mantle T.J, Fletcher J.M, Dunne A, Suppression of human alloreactive T cells by linear tetrapyrroles; relevance for transplantation, Translational Research, 178, 2016, p81-94.e2
Journal Article; Published; Peer Reviewed; Author Profiles: ECREAGH FLETCHJ AIDUNNE SBASDEO ; DOI; URL

Corr E.M, Cunningham C.C, Dunne A, Cholesterol crystals activate Syk and PI3 kinase in human macrophages and dendritic cells, Atherosclerosis, 251, 2016, p197 - 205
Journal Article; Published; Peer Reviewed; Author Profile: AIDUNNE; DOI; URL

Oliveira T, Sharkey M.A, Engel P.C, Khan A.R, Crystal structure of a chimaeric bacterial glutamate dehydrogenase, Acta Crystallographica Section:F Structural Biology Communications, 72, 2016, p462 - 466
Journal Article; Published; Peer Reviewed; Author Profile: AMIRRAFK; DOI; URL

McDonald, A.G, Tipton, K.F. and Davey, G.P. , A knowledge-based system for display and prediction of O-glycosylation network behaviour in response to enzyme knockouts, PLOS Computational Biology, 12, (4), 2016, pe1004844-
Journal Article; Published; Peer Reviewed; Author Profiles: AMCDONLD KTIPTON ; DOI; URL

McIntyre J, Verma N.K, Smith R.J, Moore C, Nerl H, McEvoy N, Berner N, McGovern I, Khan U, Lyons P, O'Neill L, Nicolosi V, Duesberg G.S, Byrne H.J, Coleman J, Volkov Y, A comparison of catabolic pathways induced in primary macrophages by pristine single walled carbon nanotubes and pristine graphene, RSC Advances, 6, (70), 2016, p65299 - 65310
Journal Article; Published; Peer Reviewed; Author Profiles: LAONEILL IMCGOVRN COLEMAJ NICOLOV MCEVOYNI DUESBERG ; DOI; URL

McDonald AG, Tipton KF, Davey GP, A Knowledge-Based System for Display and Prediction of O-Glycosylation Network Behaviour in Response to Enzyme Knockouts., PLoS computational biology, 12, (4), 2016, pe1004844
Journal Article; Published; Peer Reviewed; Author Profile: GDAVEY; DOI

Brennan K, McSharry BP, Keating S, Petrasca A, O'Reilly VP, Keane J, Doherty DG, Gardiner CM, Human Natural Killer cell expression of ULBP2 is associated with a mature functional phenotype., Human immunology, 77, (10), 2016, p876-885
Journal Article; Published; Peer Reviewed; Author Profiles: DOHERTDE GARDINEC PETRASAN JOSEPHMK ; DOI

Martin DS, Leonard S, Devine R, Redondo C, Kinsella GK, Breen CJ, McEneaney V, Rooney MF, Munsey TS, Porter RK, Sivaprasadarao A, Stephens JC, Findlay JB., Novel mitochondrial complex I inhibitors restore glucose-handling abilities of high-fat fed mice., J Mol Endocrinol , 56, (3), 2016, p261 - 271
Journal Article; Published; Peer Reviewed; Author Profiles: ROONEYM4 RKPORTER ; DOI

Kinsella P, Greene LM, Bright SA, Pollock JK, Butini S, Campiani G, Bauer S, Williams DC, Zisterer DM, The novel pyrrolo-1,5-benzoxazepine, PBOX-15, synergistically enhances the apoptotic efficacy of imatinib in gastrointestinal stromal tumours; suggested mechanism of action of PBOX-15., Investigational new drugs, 34, (2), 2016, 159-167
Journal Article; Published; Peer Reviewed; Author Profiles: DZISTRER DWILLIMS ; DOI

Lacey KA, Geoghegan JA, McLoughlin RM, The Role of Staphylococcus aureus Virulence Factors in Skin Infection and Their Potential as Vaccine Antigens., Pathogens (Basel, Switzerland), 5, (1), 2016, p22-
Journal Article; Published; Peer Reviewed; Author Profiles: MCLOUGRM GEOGHEJO ; DOI

Ní Cheallaigh, C., Sheedy, F.J., Harris, J., Muñoz-Wolf, N., Lee, J., West, K., McDermott, E.P., Smyth, A., Gleeson, L.E., Coleman, M., Martinez, N., Hearnden, C.H., Tynan, G.A., Carroll, E.C., Jones, S.A., Corr, S.C., Bernard, N.J., Hughes, M.M., Corcoran, S.E., O'Sullivan, M., Fallon, C.M., Kornfeld, H., Golenbock, D., Gordon, S.V., O'Neill, L.A., Keane, J. Lavelle, E.C, A Common Variant in the Adaptor Mal Regulates Interferon Gamma Signaling., Immunity, 44, (2), 2016, p368 - 379
Journal Article; Published; Peer Reviewed; Author Profiles: OSULLIM2 JOSEPHMK LAONEILL NICHEAC2 FSHEEDY CORRSC PALSSONE LAVELLEE ; URL

Gleeson LE, Sheedy FJ, Palsson-McDermott EM, Triglia D, O'Leary SM, O'Sullivan MP, O'Neill LA, Keane J, Cutting Edge: Mycobacterium tuberculosis Induces Aerobic Glycolysis in Human Alveolar Macrophages That Is Required for Control of Intracellular Bacillary Replication., Journal of immunology (Baltimore, Md. : 1950), 196, (6), 2016, p2444-2449
Journal Article; Published; Peer Reviewed; Author Profiles: PALSSONE LAONEILL JOSEPHMK OSULLIM2 FSHEEDY ; DOI; URL

Klionsky et al, Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)., Autophagy, 12, (1), 2016, p1 - 122
Journal Article; Published; Peer Reviewed; Author Profiles: JMURRAY6 NBOURKE ; DOI

Finlay CM, Stefanska AM, Walsh KP, Kelly PJ, Boon L, Lavelle EC, Walsh PT, Mills KH., Helminth Products Protect against Autoimmunity via Innate Type 2 Cytokines IL-5 and IL-33, Which Promote Eosinophilia., Journal of Immunology, 196, (2), 2016, p703-714
Journal Article; Published; Peer Reviewed; Author Profiles: WALSHP10 COFINLAY LAVELLEE MILLSK ; DOI

Loftus RM, Finlay DK, Immunometabolism; cellular metabolism turns immune regulator., Journal of Biological Chemistry, 291, (1), 2016, p1 - 10
Review Article; Published; Peer Reviewed; Author Profile: FINLAYD; DOI; URL

Fiore D, Proto MC, Pisanti S, Picardi P, Pagano Zottola AC, Butini S, Gemma S, Casagni A, Laezza C, Vitale M, Ligresti A, Di Marzo V, Zisterer DM, Nathwani S, Williams DC, Campiani G, Gazzerro P, Bifulco M, Antitumor effect of pyrrolo-1,5-benzoxazepine-15 and its synergistic effect with Oxaliplatin and 5-FU in colorectal cancer cells., Cancer biology & therapy, 17, (8), 2016, p849 - 858
Journal Article; Published; Peer Reviewed; Author Profiles: DZISTRER DWILLIMS ; DOI