Publications
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96 peer reviewed publications from 2012
Kelly, O.M. and McNamara, Y.M. and Manzke, L.H. and Meegan, M.J. and Porter, R.K., The preservation of in vivo phosphorylated and activated uncoupling protein 3 (UCP3) in isolated skeletal muscle mitochondria following administration of 3,4-methylenedioxymethamphetamine (MDMA aka ecstasy) to rats/mice, Mitochondrion, 12, (1), 2012, p110-119
McCarthy, G., Mills, E., Mill, K, Dunne, A., Osteoarthritis-Associated Basic Calcium Phosphate Crystals Induce IL-1, IL-18 and S100A8 Production in A Tyrosine Kinase Dependent Manner. , Arthritis Rheumatol. , 2012 ACR/ACHP Annual Meeting, Atlanta, 2012, 2012
Lars Manzke, An Investigation of the Physiological and pathological Role of Uncoupling Proteins, Trinity College Dublin, 2012
Martel, M.-A., Ryan, T., Bell, K., Fowler, J., McMahon, A., Al-Mubarak, B., Komiyama, N., Horsburgh, K., Kind, P., Grant, S., Wyllie, D., Hardingham, G., The Subtype of GluN2 C-terminal Domain Determines the Response to Excitotoxic Insults, 74, (3), 2012, p543-556
Richard K. Porter, Mitochondrial Uncoupling Protein 1 (UCP1) turnover and function, European Bioenergetics Conference 2012 (EBEC 2012), Freiburg, Germany, , (Sep 2012) , 2012, EBEC
Richard K. Porter, Regulation of metabolism in Cancer and Immune Cells Symposium in Trinity College Dublin, Irish Area Section of the Biochemical Society (IASBS), Trinity College Dublin, (Nov 2012) , 2012, Richard K. Porter
L.H. Manzke, K.J. Clarke, R.K. Porter, Upregulation of mitochondrial glycerol-3-phosphate dehydrogenase abundance in brown adipose tissue mitochondria from UCP1 knock-out mice, Biochimica et Biophysica Acta (BBA) - Bioenergetics, European Bioenergetics Conference 2012 (EBEC 2012), Freiburg, Germany, 15-20 September 2012, (1817), 2012, pps43-
Exley, M.A. and Lynch, L. and Nowak, M., NKT cells of cancer patients and how models can inform therapeutic plans, 2012, 129-151pp
Sestrins Link Tumor Suppressors with the AMPK -TOR Signaling Network in, editor(s)Cai Huang , Protein Phosphorylation in Human Health, Nvi Sad, Croatia, InTech, 2012, pp51 - 96, [Andrei V. Budanov]
Lee JH, Budanov AV, Talukdar S, Park EJ, Park HL, Park HW, Bandyopadhyay G, Li N, Aghajan M, Jang I, Wolfe AM, Perkins GA, Ellisman MH, Bier E, Scadeng M, Foretz M, Viollet B, Olefsky J, Karin M, Maintenance of metabolic homeostasis by Sestrin2 and Sestrin3., Cell Metabolism, 16, (3), 2012, p311 - 321
Min S, Meehan J, Sullivan LM, Harte NP, Xie Y, Davey GP, Svanborg C, Brodkorb A, Mok KH, Alternatively folded proteins with unexpected beneficial functions., Biochemical Society transactions, 40, (4), 2012, p746-51
McKay, P.B., Fayne, D., Horn, H.W., James, T., Peters, M.B., Carta, G., Caboni, L., Nevin, D.K., Price, T., Bradley, G., Williams, D.C., Rice, J.E., Lloyd, D.G., Consensus computational ligand-based design for the identification of novel modulators of human estrogen receptor alpha, Molecular Informatics, 31, (3-4), 2012, p246-258
Creagh, E.M., Inflammatory caspases during IBD, Broad Medical Research Program 'Advances in Understanding IBD', Los Angeles, USA, 22, 23 February 2012, edited by Prof. Daniel Hollander , 2012
Greene, LM, O'Boyle, NM, Nolan, DP, Meegan, MJ, Zisterer, DM, The vascular targeting agent Combretastatin-A4 directly induces autophagy in adenocarcinoma-derived colon cancer cells, Biochemical Pharmacology, 84, (5), 2012, p612-624
Diniz, DG, Foro, CAR, Turiel, MCP, Sosthenes, MCK, Demachki, S, Gomes, GF, Rego, CMD, Magalhaes, MC, Pinho, BG, Ramos, JP, Casseb, SMM, Brito, MD, da Silva, EVP, Nunes, MRT, Diniz, JAP, Cunningham, C, Perry, VH, Vasconcelos, PFC, Diniz, CWP, Environmental influences on antibody-enhanced dengue disease outcomes, MEMORIAS DO INSTITUTO OSWALDO CRUZ, 107, (8), 2012, p1021-+
Immunology of Multiple Sclerosis in, The Biology of Multiple Sclerosis, Cambridge University Press, 2012, pp1-146 , [Fletcher JM and Mills KHG]
Oficjalska, K., Laukens, D. and Creagh, E.M., Investigation of the role of caspases in a DSS-colitis model of IBD, Irish Society of Gastroenterology Winter Meeting, Dublin, Ireland, 23rd-24th Nov. 2012, 2012
Davis DH, Muniz Terrera G, Keage H, Rahkonen T, Oinas M, Matthews FE, Cunningham C, Polvikoski T, Sulkava R, MacLullich AM, Brayne C, Delirium is a strong risk factor for dementia in the oldest-old: a population-based cohort study., Brain : a journal of neurology, 135, (Pt 9), 2012, p2809-16
Artemenko, N.V., McDonald, A.G., Davey, G.P., Rudd, P.M., Databases and tools in glycobiology, Methods in Molecular Biology, 899, 2012, p325-350
Doyle SL, Husebye H, Connolly DJ, Espevik T, O'Neill LA, McGettrick AF, , The GOLD domain-containing protein TMED7 inhibits TLR4 signalling from the endosome upon LPS stimulation, Nature communications, 3, 2012, p7 - 10
Mori, A., Oleszycka, E., Sharp, F.A., Coleman, M., Ozasa, Y., Singh, M., O'Hagan, D.T., Tajber, L., Corrigan, O.I., McNeela, E.A., Lavelle, E.C., The vaccine adjuvant alum inhibits IL-12 by promoting PI3 kinase signaling while chitosan does not inhibit IL-12 and enhances Th1 and Th17 responses, European Journal of Immunology, 42, (10), 2012, p2709-2719
Caboni, L., Kinsella, G. K., Blanco, F., Fayne, D., Jagoe, W. N., Carr, M., Williams, D. C., Meegan, M. J., Lloyd, D. G., "True" Antiandrogens-Selective Non-Ligand-Binding Pocket Disruptors of Androgen Receptor-Coactivator Interactions: Novel Tools for Prostate Cancer, , J Med Chem,, 55, (4 ), 2012, p1635 - 1644
Enhancing the Teaching and Learning of Labortatory Sciences through a Virtual Learning Environment. in, editor(s)Marcus-Quinn A, Bruen C, Allen M, Dundon A, Diggins Y , The Digital Learning Revolution in Ireland : Case Studies from the National Learning Resources Service. , Cambridge, UK, Cambridge Scholars Publishing,, 2012, pp181 - 194, [Robinson GA, Nic A' Bháird N, Kelly VP]
Campbell*, M, Doyle*, SL, Ozaki, E, Salomon, RG, Mori, A, Kenna, PF, Kiang, AS, Humphries, MM, Lavelle, EC, O'Neill, LAJ, Hollyfield, JG, and Humphries, P, NLRP3 plays a protective role during the development of age related macular degeneration through the induction of IL-18 by drusen components., Nature Medicine, 18, (5), 2012, p791 - 798
Bowie, A.G., Innate sensing of bacterial cyclic dinucleotides: More than just STING, Nature Immunology, 13, (12), 2012, p1137-1139
Keely, NO, Zisterer, DM, Meegan, MJ, Design, Synthesis and Biochemical Evaluation of Estrogen Receptor Ligand Conjugates as Tumour Targeting Agents, LETTERS IN DRUG DESIGN & DISCOVERY, 9, (3), 2012, p295-304
Li, D., Boland, C., Walsh, K., Caffrey, M., Use of a Robot for High-throughput Crystallization of Membrane Proteins in Lipidic Mesophases, Journal of Visualised Experiments, 67, 2012, pe4000
Li D, Boland C, Aragao D, Walsh K, Caffrey M, Harvesting and cryo-cooling crystals of membrane proteins grown in lipidic mesophases for structure determination by macromolecular crystallography., Journal of visualized experiments : JoVE, (67), 2012, pe4001
Khelashvili, G, Albornoz, PBC, Johner, N, Mondal, S, Caffrey, M, Weinstein, H, Why GPCRs behave differently in cubic and lamellar lipidic mesophases, Journal of the American Chemical Society, 134, (38), 2012, p15858-15868
Aherne, M, Lyons, JA, Caffrey, M, A fast, simple and robust protocol for growing crystals in the lipidic cubic phase, Journal of Applied Crystallography , 45, (6), 2012, p1330-1333
Lyons JA, Aragão D, Slattery O, Pisliakov AV, Soulimane T, Caffrey M, Structural insights into electron transfer in caa3-type cytochrome oxidase., Nature, 487, (7408), 2012, p514-8
Caffrey M, Li D, Dukkipati A, Membrane protein structure determination using crystallography and lipidic mesophases: recent advances and successes., Biochemistry, 51, (32), 2012, p6266-88
Szereday L, Miko E, Meggyes M, Barakonyi A, Farkas B, Varnagy A, Bodis J, Lynch L, O'Farrelly C, Szekeres-Bartho J, Commitment of decidual haematopoietic progenitor cells in first trimester pregnancy., American journal of reproductive immunology (New York, N.Y. : 1989), 67, (1), 2012, p9-16
Meade KG, O'Gorman GM, Narciandi F, Machugh DE, O'Farrelly C, Functional characterisation of bovine interleukin 8 promoter haplotypes in vitro., Molecular immunology, 50, (1-2), 2012, p108-116
Sarwar S, Ryan EJ, Iqbal M, McCormick PA, O'Farrelly C, Hegarty J, Rapid, early and sustained virological responses in a cohort of Irish patients treated with pegylated interferon and ribavirin for chronic hepatitis C virus infection., Irish journal of medical science, 181, (1), 2012, p53-58
McMenamin M, Lysakova-Devine T, Wingfield M, O'Herlihy C, O'Farrelly C, Endometrial aspiration biopsy: a non-invasive method of obtaining functional lymphoid progenitor cells and mature natural killer cells., Reproductive biomedicine online, 25, (3), 2012, p322-328
Lynch L, Nowak M, Varghese B, Clark J, Hogan AE, Toxavidis V, Balk SP, O'Shea D, O'Farrelly C, Exley MA, Adipose tissue invariant NKT cells protect against diet-induced obesity and metabolic disorder through regulatory cytokine production., Immunity, 37, (3), 2012, p574-87
Chapwanya A, Meade KG, Foley C, Narciandi F, Evans AC, Doherty ML, Callanan JJ, O'Farrelly C, The postpartum endometrial inflammatory response: a normal physiological event with potential implications for bovine fertility., Reproduction, fertility, and development, 24, (8), 2012, p1028-1039
Nanda KS, Brady JJ, Murray BF, Sullivan O, Fearon U, McKenna MJ, Hegarty JE, O'Farrelly C, Ryan EJ, Elevated circulating osteoprotegerin and reduced matrix-metalloprotease-9 in post-menopausal women with chronic Hepatitis C virus infection., Cytokine, 60, (2), 2012, p328-33
McGovern, R.E., Fernandes, H., Khan, A.R., Power, N.P., Crowley, P.B., Protein camouflage in cytochrome c-calixarene complexes, Nature Chemistry, 4, (7), 2012, p527-533
Fernandes, H., Franklin, E., Jollivet, F., Bliedtner, K., Khan, A.R., Mapping the interactions between a RUN domain from DENND5/Rab6IP1 and sorting nexin 1., PloS one, 7, (4), 2012, pe35637
Porter, R.K., Studies on the function and regulation of mitochondrial uncoupling proteins, Advances in Experimental Medicine and Biology, 748, 2012, p171 - 184
Clarke, KJ, Adams, AE, Manzke, LH, Pearson, TW, Borchers, CH, Porter, RK, A role for ubiquitinylation and the cytosolic proteasome in turnover of mitochondrial uncoupling protein 1 (UCP1), BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, 1817, (10), 2012, p1759-1767
Greene, LM, O'Boyle, NM, Nolan, DP, Meegan, MJ, Zisterer, DM, The vascular targeting agent Combretastatin-A4 directly induces autophagy in adenocarcinoma-derived colon cancer cells, BIOCHEMICAL PHARMACOLOGY, 84, (5), 2012, p612-624
Sanderson DJ, Rawlins JN, Deacon RM, Cunningham C, Barkus C, Bannerman DM., Hippocampal lesions can enhance discrimination learning despite normal sensitivity to interference from incidental information., Hippocampus, 22, (7), 2012, p1553 - 1566
Jin T, Perry A, Jiang J, Smith P, Curry JA, Unterholzner L, Jiang Z, Horvath G, Rathinam VA, Johnstone RW, Hornung V, Latz E, Bowie AG, Fitzgerald KA, Xiao TS, Structures of the HIN domain:DNA complexes reveal ligand binding and activation mechanisms of the AIM2 inflammasome and IFI16 receptor., Immunity, 36, (4), 2012, p561-571
Stack J, Bowie AG, Poxviral protein A46 antagonizes Toll-like receptor 4 signaling by targeting BB loop motifs in Toll-IL-1 receptor adaptor proteins to disrupt receptor:adaptor interactions., The Journal of biological chemistry, 287, (27), 2012, p22672-22682
Pichlmair A, Kandasamy K, Alvisi G, Mulhern O, Sacco R, Habjan M, Binder M, Stefanovic A, Eberle CA, Goncalves A, Bürckstümmer T, Müller AC, Fauster A, Holze C, Lindsten K, Goodbourn S, Kochs G, Weber F, Bartenschlager R, Bowie AG, Bennett KL, Colinge J, Superti-Furga G, Viral immune modulators perturb the human molecular network by common and unique strategies., Nature, 487, (7408), 2012, p486-490
Tanveer R, Gowran A, Noonan J, Keating SE, Bowie AG, Campbell VA, The endocannabinoid, anandamide, augments Notch-1 signaling in cultured cortical neurons exposed to amyloid-ß and in the cortex of aged rats., The Journal of biological chemistry, 287, (41), 2012, p34709-21
Leow-Dyke S, Allen C, Denes A, Nilsson O, Maysami S, Bowie AG, Rothwell NJ, Pinteaux E, Neuronal toll-like receptor 4 signaling induces brain endothelial activation and neutrophil transmigration in vitro., Journal of neuroinflammation, 9, 2012, p230
Doyle SL, Husebye H, Connolly DJ, Espevik T, O'Neill LA, McGettrick AF, The GOLD domain-containing protein TMED7 inhibits TLR4 signalling from the endosome upon LPS stimulation., Nature communications, 3, 2012, p707
Arslan F, Houtgraaf JH, Keogh B, Kazemi K, de Jong R, McCormack WJ, O'Neill LA, McGuirk P, Timmers L, Smeets MB, Akeroyd L, Reilly M, Pasterkamp G, de Kleijn DP, Treatment with OPN-305, a humanized anti-Toll-Like receptor-2 antibody, reduces myocardial ischemia/reperfusion injury in pigs., Circulation. Cardiovascular interventions, 5, (2), 2012, p279-287
Wen H, Ting JP, O'Neill LA, A role for the NLRP3 inflammasome in metabolic diseases--did Warburg miss inflammation?, Nature immunology, 13, (4), 2012, p352-357
Aubry C, Corr SC, Wienerroither S, Goulard C, Jones R, Jamieson AM, Decker T, O'Neill LA, Dussurget O, Cossart P, Both TLR2 and TRIF contribute to interferon-ß production during Listeria infection., PloS one, 7, (3), 2012, pe33299
Doyle SL, Campbell M, Ozaki E, Salomon RG, Mori A, Kenna PF, Farrar GJ, Kiang AS, Humphries MM, Lavelle EC, O'Neill LA, Hollyfield JG, Humphries P, NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components., Nature medicine, 18, (5), 2012, p791-798
Netea MG, Wijmenga C, O'Neill LA, Genetic variation in Toll-like receptors and disease susceptibility., Nature immunology, 13, (6), 2012, p535-542
Foley NH, O'Neill LA, miR-107: a toll-like receptor-regulated miRNA dysregulated in obesity and type II diabetes., Journal of leukocyte biology, 92, (3), 2012, p521-527
Dowling JK, O'Neill LA, Biochemical regulation of the inflammasome., Critical reviews in biochemistry and molecular biology, 47, (5), 2012, p424-443
Connolly DJ, O'Neill LA, New developments in Toll-like receptor targeted therapeutics., Current opinion in pharmacology, 12, (4), 2012, p510-518
Ward SG, O'Neill LA, Spurs in the hunt for new immunomodulatory drug targets., Current opinion in pharmacology, 12, (4), 2012, p439-443
Haneklaus M, Gerlic M, Kurowska-Stolarska M, Rainey AA, Pich D, McInnes IB, Hammerschmidt W, O'Neill LA, Masters SL, Cutting edge: miR-223 and EBV miR-BART15 regulate the NLRP3 inflammasome and IL-1ß production., Journal of immunology (Baltimore, Md. : 1950), 189, (8), 2012, p3795-9
O'Neill LA, "Transflammation": when innate immunity meets induced pluripotency., Cell, 151, (3), 2012, p471-3
Jones, S.A., Sutton, C.E., Cua, D., Mills, K.H.G., Therapeutic potential of targeting IL-17 , Nature Immunology, 13, (11), 2012, p1022-1025
Enzymes: Irreversible Inhibition. in, A.G. McDonald and K.F. Tipton, Keith F. , Encyclopedia of the Life Sciences (eLS)., Chichester., John Wiley & Sons, Ltd, 2012, [A.G. McDonald and K.F. Tipton.]
Foley C, Chapwanya A, Creevey CJ, Narciandi F, Morris D, Kenny EM, Cormican P, Callanan JJ, O'Farrelly C, Meade KG, Global endometrial transcriptomic profiling: transient immune activation precedes tissue proliferation and repair in healthy beef cows., BMC genomics, 13, (1), 2012, p489
Connell S, Meade KG, Allan B, Lloyd AT, Kenny E, Cormican P, Morris DW, Bradley DG, O'Farrelly C, Avian resistance to Campylobacter jejuni colonization is associated with an intestinal immunogene expression signature identified by mRNA sequencing., PloS one, 7, (8), 2012, pe40409
Nevin DK, Peters MB, Carta G, Fayne D, Lloyd DG, Integrated virtual screening for the identification of novel and selective peroxisome proliferator-activated receptor (PPAR) scaffolds., Journal of medicinal chemistry, 55, (11), 2012, p4978-89
Blanco F, Egan B, Caboni L, Elguero J, O'Brien J, McCabe T, Fayne D, Meegan MJ, Lloyd DG, Study of E/Z isomerization in a series of novel non-ligand binding pocket androgen receptor antagonists., Journal of chemical information and modeling, 52, (9), 2012, p2387-97
Mulcahy ME, Geoghegan JA, Monk IR, O'Keeffe KM, Walsh EJ, Foster TJ, McLoughlin RM, Nasal Colonisation by Staphylococcus aureus Depends upon Clumping Factor B Binding to the Squamous Epithelial Cell Envelope Protein Loricrin., PLoS Pathogens, 8, (12), 2012, pe1003092
Min, SY, Meehan, J, Sullivan, LM, Harte, NP, Xie, YJ, Davey, GP, Svanborg, C, Brodkorb, A, Mok, KH, Alternatively folded proteins with unexpected beneficial functions, Biochemical Society Transactions, 40, 2012, p746-751
David K. Finlay, Ella Rosenzweig, Linda V. Sinclair, Carmen Feijoo-Carnero, Jens L. Hukelmann, Julia Rolf, Andrey A. Panteleyev, Klaus Okkenhaug, Doreen A. Cantrell, PDK1 regulation of mTOR and Hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells, Journal of Experimental Medicine, 209, (13), 2012, p2441 - 2453
David K Finlay, Regulation of glucose metabolism in T cells: new insight into the role of phosphoinositide 3-kinases, Frontiers in Immunology, 3, 2012, p247-
Scharfe-Nugent A, Corr SC, Carpenter SB, Keogh L, Doyle B, Martin C, Fitzgerald KA, Daly S, O'Leary JJ, O'Neill LA, TLR9 provokes inflammation in response to fetal DNA: mechanism for fetal loss in preterm birth and preeclampsia., Journal of immunology (Baltimore, Md. : 1950), 188, (11), 2012
Peral de Castro C, Jones SA, Ní Cheallaigh C, Hearnden CA, Williams L, Winter J, Lavelle EC, Mills KH, Harris J, Autophagy Regulates IL-23 Secretion and Innate T Cell Responses through Effects on IL-1 Secretion., Journal of immunology (Baltimore, Md. : 1950), 189, (8), 2012, p4144-4153
Sutton CE, Mielke LA, Mills KH, IL-17-producing gamma delta T cells and innate lymphoid cells., European Journal of Immunology, 42, (9), 2012, p2221-2231
Cunningham CC, Mills E, Mielke LA, O'Farrell LK, Lavelle E, Mori A, McCarthy GM, Mills KH, Dunne A, Osteoarthritis-associated basic calcium phosphate crystals induce pro-inflammatory cytokines and damage-associated molecules via activation of Syk and PI3 kinase., Clinical immunology (Orlando, Fla.), 144, (3), 2012, p228-236
Morine MJ, Toomey S, McGillicuddy FC, Reynolds CM, Power KA, Browne JA, Loscher C, Mills KH, Roche HM, Network analysis of adipose tissue gene expression highlights altered metabolic and regulatory transcriptomic activity in high-fat-diet-fed IL-1RI knockout mice., The Journal of nutritional biochemistry, 2012, p228-236
Higgs R, Higgins SC, Ross PJ, Mills KH, Immunity to the respiratory pathogen Bordetella pertussis., Mucosal immunology, 5, (5), 2012, p485-500
Reynolds CM, McGillicuddy FC, Harford KA, Finucane OM, Mills KH, Roche HM, Dietary saturated fatty acids prime the NLRP3 inflammasome via TLR4 in dendritic cells-implications for diet-induced insulin resistance., Molecular nutrition & food research, 56, (8), 2012, p1212-1222
Allen AC, Kelly S, Basdeo SA, Kinsella K, Mulready KJ, Mills KH, Tubridy N, Walsh C, Brady JJ, Hutchinson M, Fletcher JM, A pilot study of the immunological effects of high-dose vitamin D in healthy volunteers., Multiple sclerosis (Houndmills, Basingstoke, England), 18, (12), 2012, p1797 - 1800
Pindjakova J, Hanley SA, Duffy MM, Sutton CE, Weidhofer GA, Miller MN, Nath KA, Mills KH, Ceredig R, Griffin MD, Interleukin-1 accounts for intrarenal Th17 cell activation during ureteral obstruction., Kidney International, 81, (4), 2012, p379-390
Field RH, Gossen A, Cunningham C, Prior pathology in the basal forebrain cholinergic system predisposes to inflammation-induced working memory deficits: reconciling inflammatory and cholinergic hypotheses of delirium., The Journal of Neuroscience, 32, (18), 2012, p6288 - 6294
McLoughlin RM, Calatroni A, Visness CM, Wallace PK, Cruikshank WW, Tuzova M, Ly NP, Ruiz-Perez B, Kattan M, Bloomberg GR, Lederman H, Gern JE, Gold DR, Longitudinal relationship of early life immunomodulatory T cell phenotype and function to development of allergic sensitization in an urban cohort., Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 42, (3), 2012, p392-404
Bowie, A.G., The STING in the Tail for Cytosolic DNA-Dependent Activation of IRF3, Science Signalling, 5, 2012, ppe5
Olivieri A, Tipton K, O'Sullivan J, Characterization of the in vitro binding and inhibition kinetics of primary amine oxidase/vascular adhesion protein-1 by glucosamine., Biochimica et biophysica acta, 1820, (4), 2012, p482-487
Caboni L, Kinsella GK, Blanco F, Fayne D, Jagoe WN, Carr M, Williams DC, Meegan MJ, Lloyd DG, 'True' antiandrogens - selective non ligand-binding pocket disruptors of androgen receptor-coactivator interactions: Novel Tools for Prostate Cancer., Journal of Medicinal Chemistry, 55, (4), 2012, p1635 - 1644
Conroy H, Galvin KC, Higgins SC, Mills KH, Gene silencing of TGF-ß1 enhances antitumor immunity induced with a dendritic cell vaccine by reducing tumor-associated regulatory T cells., Cancer Immunology & Immunotherapy, 61, (3), 2012, p425-431
Jean M Fletcher, Sharee A Basdeo, Aideen C Allen and Padraic J Dunne, Therapeutic use of vitamin D and its analogues in autoimmunity, Recent Patents in Inflammation Allergy Drug Discovery, 6, (1), 2012, p22 - 34
Coleman MM, Finlay CM, Moran B, Keane J, Dunne PJ, Mills KH, The Immunoregulatory role of CD4(+) FoxP3(+) CD25(-) regulatory T cells in lungs of mice infected with Bordetella pertussis., FEMS Immunology and Medical Microbiology, 64, (3), 2012, p413 - 424
Marshall NA, Galvin KC, Corcoran AM, Boon L, Higgs R, Mills KH, Immunotherapy with PI3K inhibitor and Toll-like receptor agonist induces IFN-ã+IL-17+ polyfunctional T-cells that mediate rejection of murine tumors, Cancer Research, 72, (3), 2012, p581-591
Tânia Oliveira, Santosh Panjikar, John B. Carrigan, Muaawia Hamza, Paul C. Engel, Amir R. Khan, Crystal Structure of NAD-dependent Peptoniphilus Asaccharolyticus Glutamate Dehydrogenase Reveals Determinants of Cofactor Specificity, Journal of Structural Biology, 177, (2), 2012, p543-552
Immunostimulatory properties of biodegradable microparticles in, editor(s)John H. Morrow, Clint Schmidt, Nadeem Sheikh, Huw Davies , Vaccinology: Principles and Practice., Wiley-Blackwell, 2012, [Sharp, F.A. and Lavelle, E.C ]
Cunningham C, Skelly DT, Non-Steroidal Anti-Inflammatory Drugs and Cognitive Function: Are Prostaglandins at the Heart of Cognitive Impairment in Dementia and Delirium ?, Journal of Neuroimmune Pharmacology : The Official Journal of the Society on NeuroImmune Pharmacology, 7, (1), 2012, p60-73
Orlagh M. Kelly, Yvonne M. McNamara, Lars H. Manzke, Mary J. Meegan, Richard K. Porter, The Preservation of in vivo Phosphorylated and Activated Uncoupling Protein 3 (UCP3) in Isolated Skeletal Muscle Mitochondria following Administration of 3,4-Methylenedioxymethamphetamine (MDMA aka Ecstasy) to Rats/Mice, Mitochondrion, 12, (1), 2012, p110-9
Carol Murray, David Sanderson, Chris Barkus, R.M.J. Deacon, J.N.P. Rawlins, David Bannerman and Colm Cunningham, Systemic inflammation induces acute working memory deficits in the primed brain; relevance for delirium, Neurobiology of Aging, 33, (3), 2012, p603-616.e3
McNeela, E.A. and Lavelle, E.C. , Recent advances in microparticles and nanoparticles for mucosal vaccination , Current Topics in Microbiology and Immunology, 354, 2012, p75-99