Publications
Show: AllPeer ReviewedNon Peer Reviewed
129 peer reviewed publications from 2011
Pazderska, A, Wanic, K, O'Hanlon, D, Cooper, D, Collura, N,Clarke, KJ, O'Gorman, DJ, Porter, RK, Zorzano, A,Nolan, JJ , Increased skeletal muscle mitochondrial respiration in patients with type 2 diabetes following dietary and exercise interventions, DIABETOLOGIA, 47th Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD), 54, 2011, ppS248- - S248
Kieran J. Clarke, An investigation into the role and regulation of uncoupling protein 1 (UCP 1), Trinity College Dublin, 2011
Alison E. Adams, Investigation into the physiological expression and function of mitochondrial uncoupling protein 1 (UCP1) in the thymus., 2011
Richard K. Porter, "The Preservation of in vivo Phosphorylated and Activated Uncoupling Protein 3 (UCP3) in Isolated Skeletal Muscle Mitochondria following Administration of 3,4-Methylenedioxymethamphetamine (MDMA aka Ecstasy) to Mice" , COST meeting Wageningen University, The Netherlands, April 2011, Wageningen University, The Netherlands, April 2011, 2011, COST Mitofood
Richard K. Porter, The Preservation of in vivo Phosphorylated and Activated Uncoupling Protein 3 (UCP3) in Isolated Skeletal Muscle Mitochondria following Administration of 3,4-Methylenedioxymethamphetamine (MDMA aka Ecstasy) to Mice , Mitochondria in Physiology Society (MiPS) meeting,, University of Bordeaux, France, (Sep 2011) , 2011, MiPS
Höfer, N., Aragão, D., Caffrey, M. , The lipidic cubic phase as a membrane mimetic, Biophysical Journal , 100, (8), 2011, p2075 -
O'Connell, J. and Lynch, L. and Hogan, A. and Cawood, T.J. and O'Shea, D., Preadipocyte factor-1 is associated with metabolic profile in severe obesity, Journal of Clinical Endocrinology and Metabolism, 96, (4), 2011, pE680-E684
Exley, M.A. and Lynch, L. and Varghese, B. and Nowak, M. and Alatrakchi, N. and Balk, S.P., Developing understanding of the roles of CD1d-restricted T cell subsets in cancer: Reversing tumor-induced defects, Clinical Immunology, 140, (2), 2011, p184-195
Park, EJ ; Dhar, D ; Lee, J ; Kim, H ; Li, N ; Ali, SR ; Budanov, AV ; Paik, YH ; Iwaisako, K ; Karin, M ; Brenner, D ; Seki, E, IL-6/STAT3-INDUCED MTOR AND AUTOPHAGY SIGNALING IN OBESITY-PROMOTED LIVER CANCER, 62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), San Francisco, CA, NOV 04-08, 54, WILEY-BLACKWELL, COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA, 2011, pp388A - 388A
Budanov AV, Stress-responsive sestrins link p53 with redox regulation and mammalian target of rapamycin signaling., Antioxidant & Redox Signaling, 15, (6), 2011, p1679 - 1690
O'Neill, L.A., Sheedy, F.J., McCoy, C.E., MicroRNAs: The fine-tuners of Toll-like receptor signalling, Nature Reviews Immunology, 11, (3), 2011, p163-175
Rayner, K.J., Esau, C.C., Hussain, F.N., McDaniel, A.L., Marshall, S.M., Van Gils, J.M., Ray, T.D., Sheedy, F.J., Goedeke, L., Liu, X., Khatsenko, O.G., Kaimal, V., Lees, C.J., Fernandez-Hernando, C., Fisher, E.A., Temel, R.E., Moore, K.J., Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides, Nature, 478, (7369), 2011, p404-407
Rayner, K.J., Sheedy, F.J., Esau, C.C., Hussain, F.N., Temel, R.E., Parathath, S., Van Gils, J.M., Rayner, A.J., Chang, A.N., Suarez, Y., Fernandez-Hernando, C., Fisher, E.A., Moore, K.J., Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis, Journal of Clinical Investigation, 121, (7), 2011, p2921-2931
Treatment of Chronic Myeloid leukaemia: current practise and future prospects in, editor(s)Steffen Koschmieder and Utz Krug , Myeloid Leukemia Clinical Diagnosis & Treatment, Croatia, Intech, 2011, pp1 - 24, [Daniela M. Zisterer]
MacLullich, A.M.J., Edelshain, B.T., Hall, R.J., (...), De Rooij, S.E., Van Munster, B.C., Cerebrospinal fluid interleukin-8 levels are higher in people with hip fracture with perioperative delirium than in controls, Journal of the American Geriatrics Society, 59, (6), 2011, p1151-1153
Li, DF, Lee, J, Caffrey, M, Crystallizing Membrane Proteins in Lipidic Mesophases. A Host Lipid Screen, CRYSTAL GROWTH & DESIGN, 11, (2), 2011, p530-537
Höfer N, Aragão D, Lyons JA, Caffrey M., Membrane Protein Crystallization in Lipidic Mesophases. Hosting lipid affects on the crystallization and structure of a transmembrane peptide., Cryst Growth Design, 11, (4), 2011, p1182-1192
Munster BC, Aronica E, Zwinderman AH, Eikelenboom P, Cunningham C, Rooij SE, Neuroinflammation in delirium: a postmortem case-control study., Rejuvenation research, 14, (6), 2011, p615-22
De La Vega, M., Kelvin, A.A., Dunican, D.J., McFarlane, C., Burrows, J.F., Jaworski, J., Stevenson, N.J., Dib, K., Rappoport, J.Z., Scott, C.J., Long, A., Johnston, J.A., The deubiquitinating enzyme USP17 is essential for GTPase subcellular localization and cell motility, Nature Communications, 2, (1), 2011, p259
Gardiner, C.M., Morrison, M.H., Dring, M.M., Reply to KrÃ"mer et al.: Human natural killer (NK) cell inhibition by IL28A, Proceedings of the National Academy of Sciences of the United States of America, 108, (34), 2011, pE521-E522
Hogan AE, Corrigan MA, O'Reilly V, Gaoatswe G, O'Connell J, Doherty DG, Lynch L, O'Shea D, Cigarette smoke alters the invariant natural killer T cell function and may inhibit anti-tumor responses., Clinical immunology (Orlando, Fla.), 140, (3), 2011, p229-35
Bane, F.T., Bannon, J.H., Pennington, S.R., Campiani, G., Williams, D.C., Zisterer, D.M., Mc Gee, M.M., The microtubule-targeting agents, PBOX-6 [Pyrrolobenzoxazepine 7-[(dimethylcarbamoyl)oxy]-6-(2-naphthyl)pyrrolo-[2,1-d] (1,5)-benzoxazepine] and paclitaxel, induce nucleocytoplasmic redistribution of the peptidyl-prolyl isomerases, cyclophilin A and Pin1, in malignant hematopoietic cells (Journal of Pharmacology and Experimental Therapeut (2009) 329, (38-47)), 2011, p729
Finlay D, Cantrell D, The coordination of T-cell function by serine/threonine kinases., Cold Spring Harbor perspectives in biology, 3, (1), 2011, pa002261
Li D, Caffrey M, Lipid cubic phase as a membrane mimetic for integral membrane protein enzymes., Proceedings of the National Academy of Sciences of the United States of America, 108, (21), 2011, p8639-44
Caffrey M, Crystallizing membrane proteins for structure-function studies using lipidic mesophases., Biochemical Society transactions, 39, (3), 2011, p725-32
Rasmussen SG, DeVree BT, Zou Y, Kruse AC, Chung KY, Kobilka TS, Thian FS, Chae PS, Pardon E, Calinski D, Mathiesen JM, Shah ST, Lyons JA, Caffrey M, Gellman SH, Steyaert J, Skiniotis G, Weis WI, Sunahara RK, Kobilka BK, Crystal structure of the ß2 adrenergic receptor-Gs protein complex., Nature, 477, (7366), 2011, p549-55
Foley, C., O'Farrelly, C., Meade, K.G, Technical note: Comparative analyses of the quality and yield of genomic DNA from invasive and noninvasive, automated and manual extraction methods, Journal of Dairy Science, 94, (6), 2011, p3159-3165ds
Tobin, A.M., Lynch, L., Kirby, B., O'Farrelly, C., Natural killer cells in psoriasis, Journal of Innate Immunity , 3, (4), 2011, 403-410
Ryan, E.J., O'Farrelly, C., The affect of chronic hepatitis C infection on dendritic cell function: A summary of the experimental evidence, Journal of Viral Hepatitis, 18, (9), 2011, p601-607
Ryan, E.J., Stevenson, N.J., Hegarty, J.E., O'Farrelly, C., Chronic hepatitis C infection blocks the ability of dendritic cells to secrete IFN-α and stimulate T-cell proliferation, Journal of Viral Hepatitis , 18, (12), 2011, p840-851
Sultana, A., Jin, Y., Dregger, C., Franklin, E., Weisman, L.S., Khan, A.R., The activation cycle of Rab GTPase Ypt32 reveals structural determinants of effector recruitment and GDI binding, FEBS Letters, 585, (22), 2011, 3520-3527
Jin, Y., Sultana, A., Gandhi, P., Franklin, E., Hamamoto, S., Khan, A.R., Munson, M., (...), Weisman, L.S., Myosin V transports secretory vesicles via a Rab GTPase cascade and interaction with the exocyst complex, Developmental Cell, 21, (6), 2011, p1156-1170
Fadda, L, O'Connor, GM, Kumar, S, Piechocka-Trocha, A, Gardiner, CM, Carrington, M, McVicar, DW, Altfeld, M, Common HIV-1 Peptide Variants Mediate Differential Binding of KIR3DL1 to HLA-Bw4 Molecules, JOURNAL OF VIROLOGY, 85, (12), 2011, p5970-5974
Borner R, Bento-Torres J, Souza DR, Sadala DB, Trevia N, Farias JA, Lins N, Passos A, Quintairos A, Diniz JA, Perry VH, Vasconcelos PF, Cunningham C, Picanço-Diniz CW. , Early behavioral changes and quantitative analysis of neuropathological features in murine prion disease: Stereological analysis in the albino Swiss mice model., Prion, 5, (3), 2011, 215-227
Niall Connolly, How the Dead Live, Philosophia, 39, (1), 2011, p83 - 103
O'Neill LA, Bowie AG, The powerstroke and camshaft of the RIG-I antiviral RNA detection machine., Cell, 147, (2), 2011, p259-261
Ultaigh SN, Saber TP, McCormick J, Connolly M, Dellacasagrande J, Keogh B, McCormack W, Reilly M, O'Neill LA, McGuirk P, Fearon U, Veale DJ, Blockade of Toll-like receptor 2 prevents spontaneous cytokine release from rheumatoid arthritis ex vivo synovial explant cultures., Arthritis research & therapy, 13, (1), 2011, pR33
Tipton KF, Davey GP, McDonald AG, Kinetic behavior and reversible inhibition of monoamine oxidases--enzymes that many want dead., International review of neurobiology, 100, 2011, p43-64
Freinbichler W, Colivicchi MA, Stefanini C, Bianchi L, Ballini C, Misini B, Weinberger P, Linert W, Vare"lija D, Tipton KF, Della Corte L, Highly reactive oxygen species: detection, formation, and possible functions., Cellular and molecular life sciences : CMLS, 68, (12), 2011, p2067-2079
Ivanov, KL, Lukzen, NN, Morozova, OB, Mok, KH, Yurkovskaya, AV, Quantitative Approach to CIDNP in Proteins with Several Polarizable Residues on the Surface, Applied Magnetic Resonance , 41, 2011, 251-266
Butini S., Gemma S., Brindisi M., Borrelli G., Lossani A., Ponte A.M., Torti A., Maga G., Marinelli L., La Pietra V., Fiorini I., Lamponi S., Campiani G., Zisterer D.M., Nathwani S.M., Sartini S., La Motta C., Da Settimo F., Novellino E., Focher F. , Non-nucleoside inhibitors of human adenosine kinase: synthesis, molecular modeling, and biological studies. , Journal of Medicinal Chemistry, 54, (5), 2011, p1401 - 1420
Greene L.M., Carr M., Keeley N.O., Lawler M., Meegan M.J., Zisterer D.M., BubR1 is required for the mitotic block induced by combretastatin-A4 and a novel cis-restricted ß-lactam analogue in human cancer cells. , International Journal of Molecular Medicine, 27, (5), 2011, p715 - 723
Coll RC, O'Neill LA., The Cytokine Release Inhibitory Drug CRID3 Targets ASC Oligomerisation in the NLRP3 and AIM2 Inflammasomes, PLoS ONE, 6, (12, e29539), 2011
Kate E Killick, John A Browne, Stephen DE Park, David A Magee, Irene Martin, Kieran G Meade, Stephen V Gordon, Eamonn Gormley, Cliona O'Farrelly, Karsten Hokamp and David E MacHugh, Genome-wide transcriptional profiling of peripheral blood leukocytes from cattle infected with Mycobacterium bovis reveals suppression of host immune genes, BMC Genomics , 12, (611), 2011
Mills KH, TLR-dependent T cell activation in autoimmunity., Nature Reviews Immunology, 11, (12), 2011, p807-22
Byrne WL, Mills KH, Lederer JA, O'Sullivan GC, Targeting regulatory T cells in cancer., Cancer research, 71, (22), 2011, p6915-6920
Sisti F, Fernández J, Higgins SC, Casabuono A, Couto A, Mills KH, Hozbor D, A deep rough type structure in Bordetella bronchiseptica lipopolysaccharide modulates host immune responses., Microbiology and immunology, 55, (12), 2011, p847-854
Nevin DK, Lloyd DG, Fayne D, Rational targeting of peroxisome proliferating activated receptor subtypes., Current medicinal chemistry, 18, (36), 2011, p5598-623
Burleigh SC, van de Laar T, Stroop CJ, van Grunsven WM, O'Donoghue N, Rudd PM, Davey GP, Synergizing metabolic flux analysis and nucleotide sugar metabolism to understand the control of glycosylation of recombinant protein in CHO cells., BMC biotechnology, 11, 2011, p95
Dianfan Li, Martin Caffrey, Lipid cubic phase as a membrane mimetic for integral membrane protein enzymes, PNAS, 108, (21), 2011, p8639-8644
Ceara E. Walsh, Elizabeth J. Ryan, Cliona O'Farrelly, Lucy Golden-Mason, Oliver FitzGerald, Douglas J. Veale, Barry Bresnihan, Ursula Fearon, Differential Expression of NK Receptors CD94 and NKG2A by T Cells in Rheumatoid Arthritis Patients in Remission Compared to Active Disease, PLoS One, 6, (11, e27182), 2011
Stevenson NJ, Murphy AG, Bourke NB, Keogh CA, Hegarty JE, O'Farrelly C, Ribavirin Enhances IFN-α Signalling and MxA Expression: A Novel Immune Modulation Mechanism during Treatment of HCV, PLoS One, 6, (11), 2011, pe27866
O'Neill LA, A critical role for citrate metabolism in LPS signalling., The Biochemical journal, 438, (3 ), 2011, pe5-6
Li ková K, Auty MAE, Chaurin V, Min S, Mok KH, O'Brien N, Kelly AL, Brodkorb, A, Cytotoxic complexes of sodium oleate with β-lactoglobulin., European Journal of Lipid Science and Technolology, 113, (10), 2011, p1207 - 1218
McManus, G., Costa, M., Canals A., Coll, M., & Mantle, T.J. , Site-directed mutagenesis of mouse glutathione transferase P1-1 unlocks masked co-operativity, introduces a novel mechansim for ping-pong kinetic behaviour and provides further structural evidence for participation of a water molecule in proton abstraction from glutathione, FEBS Journal, 278, 2011, p273 - 281
Dungan, L.S., and Mills, K.H.G , Caspase-1-processed IL-1 family cytokines play a vital role in driving innate IL-17. , Cytokine, 56, (1), 2011, p126 - 132
Aisling Dunne, Inflammasome activation: from inflammatory disease to infection, Biochemical Society Transactions, 39, 2011
Aisling Dunne, Neil Marshall, Kingston Mills, Targeting Toll-like receptors, by Dunne, A., Marshall N.M. and Mills, K.H. , Current Opinion Pharmacology, 11, 2011, p404-11
Holmes C, Cunningham C, Zotova E, Culliford D, Perry VH., Proinflammatory cytokines, sickness behavior, and Alzheimer disease., Neurology, 77, (3), 2011, p212 - 218
Shun-ichiro Oda, Edward Franklin, Amir R. Khan, Poxvirus A46 protein binds to TIR domain-containing Mal/TIRAP via an a-helical sub-domain, Molecular Immunology, 48, 2011, p2144 - 2150
McLoughlin RM, Topley, N, Switching on EMT in the peritoneal membrane: considering the evidence. , Nephrology Dialysis and Transplant, 26, (1), 2011, p12 - 15
Chi A, Wildfire J, McLoughlin R, Wood RA, Bloomberg GR, Kattan M, Gergen P, Gold DR, Witter F, Chen T, Holick M, Visness C, Gern J, O'Connor GT, Umbilical cord plasma 25-hydroxyvitamin D concentration and immune function at birth: the Urban Environment and Childhood Asthma study., Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 41, (6), 2011, p842-50
Cohen-Poradosu R, McLoughlin RM, Lee JC, Kasper DL, Bacteroides fragilis-stimulated interleukin-10 contains expanding disease., The Journal of infectious diseases, 204, (3), 2011, p363-71
Future Trends of Novel Vaccine Adjuvants in, editor(s)Duc Hong Le, E , Immunologic Adjuvants, Future Science Group, 2011, pp104 - 116, [Schijns, V.E.J.C. and Lavelle, E.C]
Rationales for including adjuvants in vaccines in, editor(s)Duc Hong Le , Novel Immunologic Adjuvants, Future Medicine Ltd, 2011, pp6 - 14, [Schijns, V.E.J.C. and Lavelle, E.C]
Lavelle, E.C., McNaughton, A. and McNeela, E.A., NLRP3 in protective immunity and vaccination against respiratory infection, Expert Review of Vaccines, 10, (3), 2011, p255 - 257
Schijns,V.E.J.C and Lavelle, E.C, Trends in vaccine adjuvants. , Expert Reviews in Vaccines., 10, (4), 2011, p539 - 550
Afonina, I.S., Tynan, G.A., Logue, S. E., Cullen, S.P., Bots, M., Lüthi, A.U., Reeves, E.P., McElvaney, N.G., Medema, J.P., Lavelle, E.C. and Martin, S.J., Granzyme B-dependent proteolysis acts as a switch to enhance the pro-inflammatory activity of IL-1, Molecular Cell, 44, (2), 2011, p465 - 478
Ruane D.T and Lavelle E.C. , The role of CD103+ dendritic cells in the intestinal mucosal immune system. , Frontiers in Immunology , 2, 2011, p25
Finlay DK, Cantrell DA, The co-ordination of T cell function by Serine/threonine kinases, Cold Spring Harbour Perspectives in Biology, 3, (1), 2011
Finlay DK, Cantrell DA, Metabolism, migration and memory in cytotoxic T cells, Nature Reviews Immunology, 11, (2), 2011, p109 - 117
Macintyre A, Finlay DK, Preston G, Sinclair LV, Waugh CM, Tamas P, Feijoo C, Okkenhaug K, Cantrell DA, Protein kinase B controls transcriptional programs that direct cytotoxic T cell fate but is dispensable for T cell metabolism, Immunity, 34, (2), 2011, p224 - 236
Keating, S.E., Baran, M & Bowie, A.G., Cytosolic DNA sensors regulating type I interferon induction, Trends in Immunology, 32, 2011, p574 - 581
Paludan, S.R., Levy, O. & Bowie, A.G., Toll2011 at Lago di Garda: studying danger sensors by the guard towers at the lake, Nature Immunology, 12, 2011, p805 - 808
Unterholzner, L. & Bowie, A.G., Innate DNA Sensing Moves to the Nucleus, Cell Host and Microbe, 9, 2011, p351 - 353
Paludan, S.R., Bowie, A.G., Horan, K.A., Fitzgerald, K.A., Recognition of herpesviruses by the innate immune system, Nature Reviews Immunology, 11, 2011, p143 - 154
Dunne A, Marshall NA, Mills KH, TLR based therapeutics., Current opinion in pharmacology, 11, (4), 2011, p404-11
McGillicuddy FC, Harford KA, Reynolds CM, Oliver E, Claessens M, Mills KH, Roche HM, Lack of interleukin-1 receptor I (IL-1RI) protects mice from high-fat diet-induced adipose tissue inflammation coincident with improved glucose homeostasis., Diabetes, 60, (6), 2011, p1688-98
Nathalie Court, Stéphanie Rose, Marie-Laure Bourigault, Sophie Front, Olivier R. Martin, Jennifer K. Dowling, Elaine F. Kenny, Luke O'Neill, François Erard, Valerie F. J. Quesniaux, Mycobacterial PIMs Inhibit Host Inflammatory Responses through CD14-Dependent and CD14-Independent Mechanisms, PLoS ONE, 6, (9, e24631), 2011
Seán M Kilbride, Sonia A Gluchowska, Jayne E Telford, Catherine O'Sullivan and Gavin P Davey, High-level inhibition of mitochondrial complexes III and IV is required to increase glutamate release from the nerve terminal, Molecular Neurodegeneration , 6, (53), 2011
Petrovic D., Stamataki Z., Dempsey E., Golden-Mason L., Freeley M., Doherty D., Prichard D., Keogh C., Conroy J., Mitchell S., Volkov Y., McKeating J.A., O'Farrelly C., Kelleher D., Long A., Hepatitis C virus targets the Tcell secretory machinery as a mechanism of immune evasion, Hepatology, 53, (6), 2011, p1846 - 1853
Leonie Unterholzner, Rebecca P. Sumner, Marcin Baran, Hongwei Ren, Daniel S. Mansur, Nollaig M. Bourke, Felix Randow, Geoffrey L. Smith, Andrew G. Bowie, Vaccinia Virus Protein C6 Is a Virulence Factor that Binds TBK-1 Adaptor Proteins and Inhibits Activation of IRF3 and IRF7, PLoS Pathogens, 7, (9, e1002247), 2011
Carpenter S, Wochal P, Dunne A, O'Neill LA, Toll-like receptor (TLR) 3 signaling requires the TLR4 interactor with leucine-rich repeats (TRIL)., The Journal of Biological Chemistry, 286, (44), 2011, p38795-38804
Fernandes H, Franklin E, Khan AR, Crystallization of an engineered RUN domain of Rab6-interacting protein 1/DENND5., Acta Crystallographica. Section F, Structural Biology and Crystallization Communications, 67, (Pt 5), 2011, p556-60
Muhammad M. Alam and Luke A. O'Neill, MicroRNAs and the resolution phase of inflammation in macrophages, European Journal of Immunology, 41, (9), 2011, p2482-2485
O'Boyle, N.M., Knox, A.J.S., Price, T.P., Williams, D.C., Zisterer, D.M., Lloyd, D.G., Meegan, M.J., Lead identification of beta-lactam and related imine inhibitors of the molecular chaperone heat shock protein 90, Bioorganic & Medicinal Chemistry, 19, (20), 2011, p6055-6068
Hogan AE, Tobin AM, Ahern T, Corrigan MA, Gaoatswe G, Jackson R, O'Reilly V, Lynch L, Doherty DG, Moynagh PN, Kirby B, O'Connell J, O'Shea D, Glucagon-like peptide-1 (GLP-1) and the regulation of human invariant natural killer T cells: lessons from obesity, diabetes and psoriasis., Diabetologia, 2011
O'Boyle, NM, Carr, M, Greene, LM, Keely, NO, Knox, AJS, McCabe, T, Lloyd, DG, Zisterer, DM, Meegan, MJ, Synthesis, Biochemical and Molecular Modelling Studies of Antiproliferative Azetidinones causing Microtubule Disruption and Mitotic Catastrophe, European Journal of Medicinal Chemistry, 46, (9), 2011, p4595 - 4607
Colm Cunningham, Systemic inflammation and delirium: important co-factors in the progression of dementia, Biochemical Society Transactions, 39, 2011, p945 - 953
Eve Draper, Clare M. Reynolds, Mary Canavan, Kingston H. Mills, Christine E. Loscher, and Helen M. Roche, Omega-3 fatty acids attenuate dendritic cell function via NF-kappa B independent of PPAR gamma, Journal of Nutritional Biochemistry, 22, (8), 2011, p784-790
McLoughlin, R.M., Mills, K.H.G., Influence of gastrointestinal commensal bacteria on the immune responses that mediate allergy and asthma, Journal of Allergy and Clinical Immunology, 127, (5), 2011, p1097-1107
Brereton, C.F., Sutton, C.E., Ross, P.J., Iwakura, Y., Pizza, M., Rappuoli, R., Lavelle, E.C., Mills, K.H.G., Escherichia coli heat-labile enterotoxin promotes protective Th17 responses against infection by driving innate IL-1 and IL-23 production, Journal of Immunology, 186, (10), 2011, p5896-5906
Lalor, S.J., Dungan, L.S., Sutton, C.E., Basdeo, S.A., Fletcher, J.M., Mills, K.H.G., Caspase-1-processed cytokines IL-1β and IL-18 promote IL-17 production by γδ and CD4 T cells that mediate autoimmunity, Journal of Immunology, 186, (10), 2011, p5738-5748
Narciandi F, Lloyd AT, Chapwanya A, O' Farrelly C, Meade KG, Reproductive tissue-specific expression profiling and genetic variation across a 19 gene bovine ß-defensin cluster., Immunogenetics, 63, (10), 2011, p641-651
Kevin P. Kennelly, Deborah M. Wallace, Toby M. Holmes, Deborah J. Hankey, Timothy S. Grant, Cliona O'Farrelly, David J. Keegan , Preparation of Pre-Confluent Retinal Cells Increases Graft Viability In Vitro and In Vivo: A Mouse Model, PLoS One, 6, (6, e21365), 2011
Anthony Ryan, Mark Lynch, Sinead M. Smith, Sylvie Amu, Hendrik J. Nel, Claire E. McCoy, Jennifer K. Dowling, Eve Draper, Vincent O'Reilly, Ciara McCarthy, Julie O'Brien, Déirdre Ní Eidhin, Mary J. O'Connell, Brian Keogh, Charles O. Morton, Thomas R. Rogers, Padraic G. Fallon, Luke A. O'Neill, Dermot Kelleher, Christine E. Loscher , A Role for TLR4 in Clostridium difficile Infection and the Recognition of Surface Layer Proteins, PLoS Pathogens, 7, (6, e1002076), 2011
O'Neill LA, Counter-regulation in the IKK family., The Biochemical Journal, 434, (1), 2011, pe1-2
Durrani O, Banahan K, Sheedy FJ, McBride L, Ben-Chetrit E, Greiner K, Vaughan RW, Kondeatis E, Hamburger J, Fortune F, Stanford MR, Murray PI, O'Neill LA, Wallace GR, TIRAP Ser180Leu polymorphism is associated with Behcet's disease., Rheumatology , 50, (10), 2011, p1760-5
Dunphy S, Gardiner CM, NK cells and psoriasis., Journal of Biomedicine & Biotechnology, 2011, 2011, p248317
Carol L Murray, Donal T Skelly and Colm Cunningham, Exacerbation of CNS inflammation and neurodegeneration by systemic LPS treatment is independent of circulating IL-1 beta and IL-6, JOURNAL OF NEUROINFLAMMATION, 8, (50), 2011
Hennessy EJ, Sheedy FJ, Santamaria D, Barbacid M, O'Neill LA., Toll-like receptor 4 (TLR4) down-regulates microRNA-107 increasing macrophage adhesion via cyclin-dependent kinase 6, Journal of Biological Chemistry, 286, (29), 2011, p25531-9
Orlagh M. Kelly, Richard K. Porter, Absence of mitochondrial uncoupling protein 3: Effect on thymus and spleen in the fed and fasted mice, Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1807, (9), 2011, p1064-1074
Marina A. Lynch and Kingston H.G. Mills, Immunology meets neuroscience - opportunities for immune intervention in neurodegenerative diseases, Brain, Behavior, and Immunity, 26, (1), 2011, p1-10
Ní Cheallaigh C, Keane J, Lavelle EC, Hope JC, Harris J., Autophagy in the immune response to tuberculosis: clinical perspectives., Clinical and Experimental Immunology, 164, (3), 2011, p291 - 300
Sinead M. Flannery, Sinead E. Keating, Joanna Syzmak and Andrew G. Bowie, HUMAN INTERLEUKIN-1 RECEPTOR ASSOCIATED KINASE-2 (IRAK-2) IS ESSENTIAL FOR TOLL-LIKE RECEPTOR-MEDIATED TRANSCRIPTIONAL AND POSTTRANSCRIPTIONAL REGULATION OF TNFα, Journal of Biological Chemistry, 286, 2011, p23688 - 23697
Tânia F. Oliveira, Edward Franklin, José P. Afonso, Amir R. Khan, Neil J. Oldham, Inês A. C. Pereira and Margarida Archer, Structural insights into dissimilatory sulfite reductases: structure of desulforubidin from Desulfomicrobium norvegicum, Frontiers in Microbial Physiology and Metabolism, 2, (71), 2011
Rakovich T, Boland C, Bernstein I, Chikwana VM, Iwata-Reuyl D, Kelly VP, Queuosine deficiency in eukaryotes compromises tyrosine production through increased tetrahydrobiopterin oxidation., The Journal of Biological Chemistry, 286, (22), 2011, p19354-19363
Dring MM, Morrison MH, McSharry BP, Guinan KJ, Hagan R, O'Farrelly C, Gardiner CM, Innate immune genes synergize to predict increased risk of chronic disease in hepatitis C virus infection., PNAS, 108, (14), 2011, p5736-41
Gillian M. Tannahill, Luke A.J. O'Neill, The emerging role of metabolic regulation in the functioning of Toll-like receptors and the NOD-like receptor Nlrp3, FEBS Letter, 585, (11), 2011, p1568-1572
Ronan G. Shaughnessy, Kieran G. Meade, Beatrice A. McGivney, Brenda Allan, Cliona O' Farrelly, Global gene expression analysis of chicken caecal response to Campylobacter jejuni, Veterinary Immunology and Immunopathology, 142, (1-2), 2011, p64-71
Paul B. McKay, Martin B. Peters, Giorgio Carta, Christopher T. Flood, Enda Dempsey, Angus Bell, Colin Berry, David G. Lloyd, Darren Fayne, Identification of Plasmepsin Inhibitors as Selective Antimalarial Agents using Ligand Based Drug Design, Bioorganic & Medicinal Chemistry Letters, 21, (11), 2011, p3335-3341
Olivieri A, Rico D, Khiari Z, Henehan G, O'Sullivan J, Tipton K, From caffeine to fish waste: amine compounds present in food and drugs and their interactions with primary amine oxidase., Journal of neural transmission (Vienna, Austria : 1996), 118, (7), 2011, p1079-1089
Hogan AE, O'Reilly V, Dunne MR, Dere RT, Zeng SG, O'Brien C, Amu S, Fallon PG, Exley MA, O'Farrelly C, Zhu X, Doherty DG, Activation of human invariant natural killer T cells with a thioglycoside analogue of á-galactosylceramide, Clinical Immunology, 140, (2), 2011, p196-207
Robert A. Alberty, Athel Cornish Bowden, Robert N. Goldberg, Gordon G. Hammes, Keith Tipton, Hans V. Westerhoff, Recommendations for terminology and databases for biochemical thermodynamics, Biophysical Chemistry, 155, (2-3), 2011, p89-103
Cheryl M. Sweeney, Roisin Lonergan, Sharee A. Basdeo, Katie Kinsella, Lara S. Dungan, Sarah C. Higgins, Patrick J. Kelly, Lisa Costelloe, Niall Tubridy, Kingston H.G. Mills, Jean M. Fletcher, IL-27 mediates the response to IFN beta therapy in multiple sclerosis patients by inhibiting Th17 cells, Brain, Behavior and Immunity, 25, (6), 2011, p1170-1181
Olivieri, A., Tipton. K., Inhibition of bovine plasma semicarbazide-sensitive amine oxidase by caffeine. , Journal of Biochemical and Molecular Toxicology, 25, 2011, p26 - 27
Forde JC, Maginn EN, McNamara G, Martin LM, Campiani G, Williams DC, Zisterer D, McElligott AM, Lawler M, Lynch TH, Hollywood D, Marignol L, Microtubule-targeting-compound PBOX-15 radiosensitizes cancer cells in vitro., Cancer biology & therapy, 11, (4), 2011, p421-8
O'Boyle, NM, Greene, LM, Bergin, O, Fichet, JB, McCabe, T, Lloyd, DG, Zisterer, DM, Meegan, MJ, Synthesis, evaluation and structural studies of antiproliferative tubulin-targeting azetidin-2-ones, Bioorganic & Medicinal Chemistry, 19, (7), 2011, p2306-2325
Rebola N, Simões AP, Canas PM, Tomé AR, Andrade GM, Barry CE, Agostinho PM, Lynch MA, Cunha RA, Adenosine A(2A) receptors control neuroinflammation and consequent hippocampal neuronal dysfunction., Journal of Neurochemistry, 117, (1), 2011, p100-111
Kawatani Y, Suzuki T, Shimizu R, Kelly VP, Yamamoto M., Nrf2 and selenoproteins are essential for maintaining oxidative homeostasis in erythrocytes and protecting against hemolytic anemia., Blood, 20, (1), 2011, p986 - 996
Harris, J..Hartman, M., Roche, C., Zeng, S.G., O'Shea, A., Sharp, F.A., Lambe, E.M., Creagh, E.M., Golenbock, D.T., Tschopp, J., Kornfeld, H., Fitzgerald, K.A. and Lavelle, E.C , Autophagy controls IL-1ß secretion by targeting pro-IL-1ß for degradation, The Journal of Biological Chemistry, 286, 2011, p9587 - 9597
Aline Andrade de Sousa, Renata Reis, João Bento-Torres, Nonata Trévia, Nara Alves de Almeida Lins, Aline Passos, Zaire Santos, José Antonio Picanço Diniz, Pedro Fernando da Costa Vasconcelos, Colm Cunningham, Victor Hugh Perry, Cristovam Wanderley Picanço Diniz, Influence of Enriched Environment on Viral Encephalitis Outcomes: Behavioral and Neuropathological Changes in Albino Swiss Mice, PLoS ONE, 6, (1, e15597), 2011
Michael Carty, Andrew G. Bowie, Evaluating the role of Toll-like Receptors in diseases of the Central Nervous system, Biochemical Pharmacology, 81, (7), 2011, p825-837
Rosenbaum DM, Zhang C, Lyons JA, Holl R, Aragao D, Arlow DH, Rasmussen SG, Choi HJ, Devree BT, Sunahara RK, Chae PS, Gellman SH, Dror RO, Shaw DE, Weis WI, Caffrey M, Gmeiner P, Kobilka BK, Structure and function of an irreversible agonist-ß(2) adrenoceptor complex., Nature, 469, (7329), 2011, p236-40
Roberta J Ward, Frederic Lallemand, Philippe de Witte, Robert R Crichton, Jacques Piette, Keith Tipton, Karl Hemmings, Arnaud Pitard, Mike Page, Laura Della Corte, Deanna Taylor, David Dexter, Anti-inflammatory actions of a taurine analogue; ethane β-sultam; in phagocytic cells; in vivo and in vitro, Biochemical Pharmacology, 81, 2011, p743 - 751
Simon J.R. Heales, Adrian Menzes, Gavin P. Davey, Depletion of glutathione does not affect electron transport chain complex activities in brain mitochondria: Implications for Parkinsons's disease and postmortem studies, Free Radical Biology and Medicine, 50, (7), 2011, p899-902
Cormac J. Whelehan, Kieran G. Meade, P. David Eckersall, Fiona J. Young, Cliona O'Farrelly, EXPERIMENTAL STAPHYLOCOCCUS AUREUS INFECTION OF THE MAMMARY GLAND INDUCES REGION-SPECIFIC CHANGES IN INNATE IMMUNE GENE EXPRESSION, Veterinary Immunology and Immunopathology, 140, (3-4), 2011, p181-189
Maginn EN, Browne PV, Hayden P, Vandenberghe E, McDonagh B, Evans P, Goodyer M, Tewari P, Campiani G, Butini S, Williams DC, Zisterer DM, Lawler MP, McElligott AM., PBOX-15, a novel microtubule targeting agent, induces apoptosis, upregulates death receptors, and potentiates TRAIL-mediated apoptosis in multiple myeloma cells., British Journal of Cancer, 104, (2), 2011, p281 - 289
Discovery of vaccine adjuvants in, editor(s)Editor Shane C. Gad. , Pharmaceutical Sciences Encyclopedia: Drug Discovery, Development, and Manufacturing., John Wiley & Sons , 2011, pp1 - 14, [Sharp, F. and Lavelle, E.C.]