Skip to main content

Trinity College Dublin, The University of Dublin

Trinity Menu Trinity Search



You are here Research > Publications

Publications

Below is the list of peer and non peer publications from the School of Biochemistry and Immunology.

Show: AllPeer ReviewedNon Peer Reviewed
116 peer reviewed publications from 2009

Pettersson-Kastberg, J., Mossberg, A.-K., Trulsson, M., Yong, Y.J., Min, S., Lim, Y., O'Brien, J.E., Svanborg, C., Mok, K.H., "-Lactalbumin, Engineered to be Nonnative and Inactive, Kills Tumor Cells when in Complex with Oleic Acid: A New Biological Function Resulting from Partial Unfolding, Journal of Molecular Biology, 394, (5), 2009, p994-1010
Journal Article; Published; Peer Reviewed; Author Profile: MOK1; DOI

Murphy, J.E.J. and Porter, R.K., The control of oxidative phosphorylation in the adrenal gland (Y1) cell line, Advances in Experimental Medicine and Biology, 645, 2009, p35-41
Journal Article; Published; Peer Reviewed; Author Profile: RKPORTER; DOI; URL

Ryan, T.J. and Grant, S.G.N., Erratum: The origin and evolution of synapses (Nature Reviews Neuroscience (2009) 10 (701-712)), Nature Reviews Neuroscience, 10, (11), 2009, p829
Journal Article; Published; Peer Reviewed; Author Profile: TRYAN6; DOI; URL

Richard K. Porter, "Mitochondrial Uncoupling Protein 1 and Immune Function" , COST meeting , Balearic Islands University, Palma, Mallorca, Spain., March, 2009, COST Mitofood
Invited Talk; Published; Peer Reviewed; Author Profile: RKPORTER

Richard K. Porter, "Efficiency of Energy Transduction in Mammals" , Invitation to Nencki Institute Warsaw, Poland., Nencki Institute Warsaw, Poland., July, 2009, Adam Szewczyk
Invited Talk; Published; Peer Reviewed; Author Profile: RKPORTER

Ryan, T.J., Grant, S.G.N., The origin and evolution of synapses, 10, (10), 2009, p701-712
Journal Article; Published; Peer Reviewed; Author Profile: TRYAN6

Daniela Zisterer, Mary Meegan, Niamh O'Boyle, Miriam Carr, Lisa Greene and Thomas Greene, 'Combretastatin Derivatives and Uses Therefor', European Patent Office, EP2338877 A1, 2009
Patent; Granted; Peer Reviewed; Author Profiles: NIOBOYLE MMEEGAN DZISTRER ; URL

Lee, JH ; Budanov, AV ; Bier, E ; Karin, M, Sestrin, a novel regulator of TOR-dependent cell growth and metabolism, DEVELOPMENTAL BIOLOGY, 68th Annual Meeting of the Society-for-Developmental-Biology, San Francisco, CA, JUL 23-27, 331, (2), ACADEMIC PRESS INC ELSEVIER SCIENCE, 525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA, 2009, pp481 - 481
Conference Paper; Published; Peer Reviewed; Author Profile: BUDANOVA; URL

Onnis, V., Kinsella, G.K., Carta, G., Fayne, D., Lloyd, D.G., Rational ligand-based virtual screening and structure-activity relationship studies in the ligand-binding domain of the glucocorticoid receptor-", Future Medicinal Chemistry, 1, (3), 2009, p483-499
Journal Article; Published; Peer Reviewed; Author Profile: FAYNED

Stevenson, N.J., Addley, M.R., Ryan, E.J., Boyd, C.R., Carroll, H.P., Paunovic, V., Bursill, C.A., Miller, H.C., Channon, K.M., McClurg, A.E., Armstrong, M.A., Coulter, W.A., Greaves, D.R., Johnston, J.A., CCL11 blocks IL-4 and GM-CSF signaling in hematopoietic cells and hinders dendritic cell differentiation via suppressor of cytokine signaling expression, Journal of Leukocyte Biology, 85, (2), 2009, p289-297
Journal Article; Published; Peer Reviewed; Author Profile: STEVENNJ; DOI

Meade, K.G., Narciandi, F., Cahalane, S., Reiman, C., Allan, B., O'Farrelly, C., Comparative in vivo infection models yield insights on early host immune response to Campylobacter in chickens, Immunogenetics, 61, (2), 2009, p101-110
Journal Article; Published; Peer Reviewed; Author Profile: OFARRECL; DOI

Lynch, L.A., O'Connell, J.M., Kwasnik, A.K., Cawood, T.J., O'Farrelly, C., O'Shea, D.B., Are natural killer cells protecting the metabolically healthy obese patient?, Obesity, 17, (3), 2009, p601-605
Journal Article; Published; Peer Reviewed; Author Profiles: OFARRECL LYNCHL3 ; DOI

Mcgrath, E., Ryan, E.J., Lynch, L., Golden-Mason, L., Mooney, E., Eogan, M., O'herlihy, C., O'Farrelly, C., Changes in endometrial natural killer cell expression of CD94, CD158a and CD158b are associated with infertility, American Journal of Reproductive Immunology, 61, (4), 2009, p265-276
Journal Article; Published; Peer Reviewed; Author Profiles: OFARRECL LYNCHL3 ; DOI

Chapwanya, A., Meade, K.G., Doherty, M.L., Callanan, John.J., Mee, J.F., O'Farrelly, C, Histopathological and molecular evaluation of Holstein-Friesian cows postpartum: Toward an improved understanding of uterine innate immunity, Theriogenology, 71, (9), 2009, p1396-1407
Journal Article; Published; Peer Reviewed; Author Profile: OFARRECL; DOI

Nanda, K.S., Ryan, E.J., Murray, B.F., Brady, J.J., McKenna, M.J., Nolan, N., O'Farrelly, C., Hegarty, J.E., Effect of Chronic Hepatitis C Virus Infection on Bone Disease in Postmenopausal Women, Clinical Gastroenterology and Hepatology, 7, (8), 2009, p894-899
Journal Article; Published; Peer Reviewed; Author Profile: OFARRECL; DOI

MacHugh, D.E., Gormley, E., Park, S.D.E., Browne, J.A., Taraktsoglou, M., O'Farrelly, C., Meade, K.G., Gene expression profiling of the host response to mycobacterium bovis infection in cattle, Transboundary and Emerging Diseases , 56, (6-7), 2009, p204-214
Journal Article; Published; Peer Reviewed; Author Profile: OFARRECL; DOI

Nemeth, E., Baird, A.W., O'Farrelly, C., Microanatomy of the liver immune system, Seminars in Immunopathology, 31, (3), 2009, p333-343
Journal Article; Published; Peer Reviewed; Author Profile: OFARRECL; DOI

O'Neill, L.A.J., O'Farrelly, C., The immune system as an invisible, silent Grand Fugue, Nature Immunology, 10, (10), 2009, p1043-1045
Journal Article; Published; Peer Reviewed; Author Profiles: OFARRECL LAONEILL ; DOI

Meade, K.G., O'Gorman, G.M., Hill, E.W., Narciandi, F., Agaba, M., Kemp, S.J., O'Farrelly, C., MacHugh, D.E., Divergent antimicrobial peptide (AMP) and acute phase protein (APP) responses to Trypanosoma congolense infection in trypanotolerant and trypanosusceptible cattle, Molecular Immunology, 47, (2-3), 2009, p196-204
Journal Article; Published; Peer Reviewed; Author Profile: OFARRECL; DOI

Fernandes, H., Franklin, E., Recacha, R., Houdusse, A., Goud, B., Khan, A.R., Structural aspects of Rab6-effector complexes, Biochemical Society Transactions, 37, (5), 2009, p1037-1041
Journal Article; Published; Peer Reviewed; Author Profile: AMIRRAFK; DOI

Crowley, P.B., Matias, P.M., Khan, A.R., Roessle, M., Svergun, D.I., Metal-mediated self-assembly of a β-sandwich protein, Chemistry - A European Journal , 15, (46), 2009, p12672-12680
Journal Article; Published; Peer Reviewed; Author Profile: AMIRRAFK; DOI

Downing, T., Lynn, D.J., Connell, S., Lloyd, A.T., Bhuiyan, A.K.F.H., Silva, P., Naqvi, A.N., (...), Bradley, D.G. , Erratum: Contrasting evolution of diversity at two disease-associated chicken genes (Immunogenetics DOI: 10.1007/s00251-009-0359-x), 2009, - 421-422
Miscellaneous; Published; Peer Reviewed; Author Profiles: DBRADLEY OFARRECL

Onnis V, Kinsella GK, Carta G, Fayne D, Lloyd DG, Rational structure-based drug design and optimization in the ligand-binding domain of the glucocorticoid receptor-"., Future medicinal chemistry, 1, (2), 2009, p345-59
Journal Article; Published; Peer Reviewed; Author Profile: FAYNED

MacKenzie MG, Hamilton DL, Murray JT, Taylor PM, Baar K, mVps34 is activated following high-resistance contractions., The Journal of physiology, 587, (Pt 1), 2009, p253-60
Journal Article; Published; Peer Reviewed; Author Profile: JMURRAY6

Immunomodulation by zwitterionic polysaccharides in, Microbial Glycobiology: Structure, Relevance and Applications, Elsevier, 2009, [McLoughlin RM, Kasper DL]
Book Chapter; Published; Peer Reviewed; Author Profile: MCLOUGRM

Ly NP, Ruiz-Perez B, McLoughlin RM, Visness CM, Wallace PK, Cruikshank WW, Tzianabos AO, O'Connor GT, Gold DR, Gern JE, Characterization of regulatory T cells in urban newborns., Clinical and molecular allergy : CMA, 7, 2009, p8
Journal Article; Published; Peer Reviewed; Author Profile: MCLOUGRM

Waugh C., Sinclair LV., Finlay DK., Bayascas J., Cantrell DA., Phosphoinositide (3,4,5)-triphosphate binding to phosphoinositide-dependent kinase 1 regulates a protein kinase B/Akt signaling threshold that dictates T-cell migration, not proliferation, Molecular Cellular Biology, 29, (21), 2009, p5952 - 5962
Journal Article; Published; Peer Reviewed; Author Profile: FINLAYD; DOI; URL

Finlay DK., Sinclair LV., Fejoo C., Waugh C., Hagenbeek TJ., Spits H., Cantrell DA. , Phosphoinositide-dependent kinase 1 controls migration and malignant transformation but not cell growth and proliferation in PTEN-null lymphocytes, Journal of Experimental Medcine, 206, (11), 2009, p2441 - 2454
Journal Article; Published; Peer Reviewed; Author Profile: FINLAYD; DOI; URL

Cormican P, Lloyd AT, Downing T, Connell SJ, Bradley D, O'Farrelly C, The avian Toll-Like receptor pathway--subtle differences amidst general conformity., Developmental and comparative immunology, 33, (9), 2009, p967-73
Journal Article; Published; Peer Reviewed; Author Profiles: DBRADLEY OFARRECL ; DOI

Effects of pH on enzymes in, editor(s)D.L Purich , Enzyme Kinetics and Mechanism, New York, USA, Academic Pres, 2009, pp124 - 178, [Tipton, K.F., McDonald, A.G., Dixon, H.B.F.]
Book Chapter; Published; Peer Reviewed; Author Profiles: KTIPTON AMCDONLD

McDonald AG, Tipton KF, Boyce S, Tracing metabolic pathways from enzyme data., Biochimica et biophysica acta, 1794, (9), 2009, p1364-71
Journal Article; Published; Peer Reviewed; Author Profile: AMCDONLD; DOI

McDonald AG, Boyce S, Tipton KF, ExplorEnz: the primary source of the IUBMB enzyme list., Nucleic acids research, 37, (Database issue), 2009, pD593-7
Journal Article; Published; Peer Reviewed; Author Profile: AMCDONLD; DOI

Monoacylglycerols: The Workhorse Lipids for Crystallizing Membrane Proteins in Mesophases in, editor(s)Dale J. Benos; Sidney A. Simon , Current Topics in Membranes, San Diego, Elsevier, 2009, pp83-108 , [M. Caffrey, J. Lyons, T. Smyth and D.J. Hart]
Book Chapter; Published; Peer Reviewed; Author Profile: MCAFFRE; DOI

Caffrey M, Cherezov V, Crystallizing membrane proteins using lipidic mesophases., Nature Protocols, 4, (5), 2009, p706-31
Journal Article; Published; Peer Reviewed; Author Profile: MCAFFRE; DOI; URL

Caffrey M, Crystallizing membrane proteins for structure determination: use of lipidic mesophases., Annual Review of Biophysics, 38, 2009, p29-51
Journal Article; Published; Peer Reviewed; Author Profile: MCAFFRE; DOI

Pettersson-Kastberg J, Mossberg AK, Trulsson M, Yong YJ, Min S, Lim Y, O'Brien JE, Svanborg C, Mok KH, Alpha-Lactalbumin, engineered to be nonnative and inactive, kills tumor cells when in complex with oleic acid: a new biological function resulting from partial unfolding, Journal of Molecular Biology, 394, (5), 2009, p994 - 1010
Journal Article; Published; Peer Reviewed; Author Profile: MOK1; DOI

Gattin Z, Riniker S, Hore PJ, Mok KH, van Gunsteren WF, Temperature and urea induced denaturation of the TRP-cage mini protein TC5b: A simulation study consistent with experimental observations, Protein Science, 18, (10), 2009, p2090 - 2099
Journal Article; Published; Peer Reviewed; Author Profile: MOK1; DOI

Wilhelm K, Darinskas A, Noppe W, Duchardt E, Mok KH, Vukojević V, Schleucher J, Morozova-Roche LA, Protein oligomerization induced by oleic acid at the solid-liquid interface--equine lysozyme cytotoxic complexes, FEBS Journal, 276, (15), 2009, p3975 - 3989
Journal Article; Published; Peer Reviewed; Author Profile: MOK1; DOI

Shun-ichiro Oda, Martina Schroder, Amir R. Khan, Structural Basis for Targeting of Human RNA Helicase DDX3 by Poxvirus Protein K7, Structure (Cell Press), 17, 2009, p1528 - 1537
Journal Article; Published; Peer Reviewed; Author Profile: AMIRRAFK

Creagh EM, Brumatti G, Sheridan C, Duriez PJ, Taylor RC, Cullen SP, Adrain C, Martin SJ, Bicaudal is a conserved substrate for Drosophila and mammalian caspases and is essential for cell survival., PloS one, 4, (3), 2009, pe5055
Journal Article; Published; Peer Reviewed; Author Profiles: ECREAGH MARTINSJ ; DOI; URL

Hayes, J.M. and Mantle, T.J., The effect of pH on the initial rate kinetics of the dimeric biliverdin-IXα reductase from the cyanobacterium Synechocystis PCC6803 , FEBS Journal, 276, 2009, p4414-4425
Journal Article; Published; Peer Reviewed; Author Profile: TMANTLE; DOI

Franklin, E., Browne, S., Horan, A.E., Inomata,K., Hammam, M.A.S., Kinoshita, H., Lamparter,T., Golfis, G. and Mantle, T.J. , The use of synthetic linear tetrapyrroles to probe the verdin sites of human biliverdin-IXα reductase and human biliverdin-IXβ reductase , FEBS Journal, 276, 2009, p4405-4413
Journal Article; Published; Peer Reviewed; Author Profile: TMANTLE; DOI

Corr, S.C. and O'Neill, L.A.J. , Genetic Variation in Toll-Like Receptor Signalling and the Risk of Inflammatory and Immune Diseases, Journal of Innate Immunity, 1, (4), 2009, p350 - 357
Journal Article; Published; Peer Reviewed; Author Profiles: LAONEILL CORRSC ; DOI

Clive Holmes, Colm Cunningham, Elina Zotova, Jan Woolford, Christine Dean, Sara Kerr, David Culliford, and Hugh Perry, Systemic inflammation and disease progression in Alzheimer's disease, Neurology, 73, (10), 2009, p768 - 774
Journal Article; Published; Peer Reviewed; Author Profile: CUNNINCO; DOI

O'Neill LA, Boosting the brain's ability to block inflammation via microRNA-132., Immunity, 31, (6), 2009, p854-855
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI

O'Neill LA, A feed-forward loop involving hyaluronic acid and toll-like receptor-4 as a treatment for colitis?, Gastroenterology., 137, (6), 2009, p1889-1891
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI

McCormack WJ, Parker AE, O'Neill LA., Toll-like receptors and NOD-like receptors in rheumatic diseases., Arthritis Research & Therapy , 11, (5), 2009, p243
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI

Carpenter S, Carlson T, Dellacasagrande J, Garcia A, Gibbons S, Hertzog P, Lyons A, Lin LL, Lynch M, Monie T, Murphy C, Seidl KJ, Wells C, Dunne A, O'Neill LA. , TRIL, a functional component of the TLR4 signaling complex, highly expressed in brain., Journal of Immunology, 183, (6), 2009, p3989-3995
Journal Article; Published; Peer Reviewed; Author Profiles: AIDUNNE LAONEILL LYNCHMA ; DOI

O'Neill LA., DNA makes RNA makes innate immunity, Cell, 138, (3), 2009, p428-430
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI

Carpenter S, O'Neill LA , Recent insights into the structure of Toll-like receptors and post-translational modifications of their associated signalling proteins., Biochemistry Journal, 422, (1), 2009, p1-10
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI

Ferwerda B, Alonso S, Banahan K, McCall MB, Giamarellos-Bourboulis EJ, Ramakers BP, Mouktaroudi M, Fain PR, Izagirre N, Syafruddin D, Cristea T, Mockenhaupt FP, Troye-Blomberg M, Kumpf O, Maiga B, Dolo A, Doumbo O, Sundaresan S, Bedu-Addo G, van Crevel R, Hamann L, Oh DY, Schumann RR, Joosten LA, de la Rúa C, Sauerwein R, Drenth JP, Kullberg BJ, van der Ven AJ, Hill AV, Pickkers P, van der Meer JW, O'Neill LA, Netea MG., Functional and genetic evidence that the Mal/TIRAP allele variant 180L has been selected by providing protection against septic shock, Proceedings of the National Academy of Science USA, 106, (25), 2009, p10272-10277
Journal Article; Published; Peer Reviewed; Author Profiles: BANAHANK LAONEILL ; DOI

O'Neill LA, Bryant CE, Doyle SL, Therapeutic targeting of toll-like receptors for infectious and inflammatory diseases and cancer., Pharmacological Reviews, 61, (2), 2009, p177-97
Journal Article; Published; Peer Reviewed; Author Profiles: DOYLES8 LAONEILL ; DOI

Corr SC, O'Neill LA, Listeria monocytogenes infection in the face of innate immunity., Cellular microbiology, 11, (5), 2009, p703 - 709
Journal Article; Published; Peer Reviewed; Author Profiles: LAONEILL CORRSC ; DOI

O'Neill LA, Regulation of signaling by non-degradative ubiquitination., The Journal of Biological Chemistry, 284, (13), 2009, p8209
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Nomenclature and potential functions of copper amine oxidases. in, editor(s)G. Floris & B. Mondovi , Copper Amine Oxidases, Boca Raton, FL, USA , CRC Press, 2009, pp5 - 17, [S. Boyce, K.F. Tipton, M.I. O'Sullivan, G.P. Davey. M. Motherway Gildea, A.G. McDonald, A. Olivieri, and J. O'Sullivan]
Book Chapter; Published; Peer Reviewed; Author Profile: KTIPTON

McDonald AG, Tipton KF and Davey GP, Mathematical modelling of metabolism, The Biochemist, 31, 2009, p24 - 27
Journal Article; Published; Peer Reviewed; Author Profiles: AMCDONLD KTIPTON

Black WJ, Stagos D, Marchitti SA, Nebert DW, Tipton KF, Bairoch A and Vasilio V., Human aldehyde dehydrogenase genes: alternatively spliced transcriptional variants and their suggested nomenclature., Pharmocogenetics and Genomica, 2009
Journal Article; In_press; Peer Reviewed; Author Profile: KTIPTON

Mills, K.H.G., Jarnicki, AJ, Toomey D, TCD, Compositions and methods for the treatment of cancer and infectious diseases, 2009, 12/085787
Patent; Published; Peer Reviewed; Author Profile: MILLSK

Mills, K.H.G. and Higgins, S., TCD, Compounds and methods for the treatment of autoimmune and inflammatory disorders, 2009, PCT/EP2009/067819
Patent; Published; Peer Reviewed; Author Profile: MILLSK

Downing T, Lynn DJ, Connell S, Lloyd AT, Bhuiyan AK, Silva P, Naqvi AN, Sanfo R, Sow RS, Podisi B, Hanotte O, O'Farrelly C, Bradley DG, Evidence of balanced diversity at the chicken interleukin 4 receptor alpha chain locus., BMC Evolutionary Biology, 9, 2009, part. no. 136
Journal Article; Published; Peer Reviewed; Author Profiles: DBRADLEY OFARRECL ; DOI; URL

Downing T, Cormican P, O'Farrelly C, Bradley DG, Lloyd AT, Evidence of the adaptive evolution of immune genes in chicken, BMC Research Notes, 2, (254), 2009, part. no. 254
Journal Article; Published; Peer Reviewed; Author Profiles: DBRADLEY OFARRECL ; DOI; URL

Diana Spitznagel, Charles Ebikeme, Marc Biran, Nóirín Nic a' Bháird, Frédéric Bringaud, Gary T. M. Henehan and Derek P. Nolan, Alanine aminotransferase of Trypanosoma brucei- a key role in proline metabolism in procyclic life forms, FEBS Journal, 276, (23), 2009, p7187 - 7199
Journal Article; Published; Peer Reviewed; Author Profile: DENOLAN; DOI

Veith H, Southall N, Huang R, James T, Fayne D, Artemenko N, Shen M, Inglese J, Austin CP, Lloyd DG, Auld DS, Comprehensive characterization of cytochrome P450 isozyme selectivity across chemical libraries., Nature Biotechnology, 27, (11), 2009, p1050-5
Journal Article; Published; Peer Reviewed; Author Profile: FAYNED; DOI; URL

Knox AJ, Price T, Pawlak M, Golfis G, Flood CT, Fayne D, Williams DC, Meegan MJ, Lloyd DG, Integration of ligand and structure-based virtual screening for the identification of the first dual targeting agent for heat shock protein 90 (Hsp90) and tubulin., Journal of medicinal chemistry, 52, (8), 2009, p2177-80
Journal Article; Published; Peer Reviewed; Author Profiles: FAYNED DWILLIMS ; DOI

Lynch L, O'Shea D, Winter DC, Geoghegan J, Doherty DG, O'Farrelly C, Invariant NKT cells and CD1d+ cells amass in human omentum and are depleted in patients with cancer and obesity., European Journal of Immunology, 39, (7), 2009, p1893-1901
Journal Article; Published; Peer Reviewed; Author Profiles: DOHERTDE LYNCHL3 OFARRECL ; DOI

Fletcher JM, Lonergan R, Costelloe L, Kinsella K, Moran B, Tubridy N and Mills KHG, CD39+Foxp3+ regulatory T cells suppress pathogenic Th17 cells and are impaired in multiple sclerosis, Journal of Immunology, 183, 2009, p7602 - 7610
Journal Article; Published; Peer Reviewed; Author Profile: MORANBA

Dunne PJ, Moran B, Cummins RC and Mills KH , CD11c+CD8alpha+ dendritic cells promote protective immunity to respiratory infection with Bordetella pertussis. , The Journal of Immunology, 183, 2009, p400 - 410
Journal Article; Published; Peer Reviewed; Author Profiles: MORANBA MILLSK ; DOI

Mills KH, Dunne A, Immune modulation: IL-1, master mediator or initiator of inflammation, Nature Medicine, 15, (12), 2009, p1363-1364
Review; Published; Peer Reviewed; Author Profiles: MILLSK AIDUNNE ; DOI

Reynolds CM, Draper E, Keogh B, Rahman A, Moloney AP, Mills KH, Loscher CE, Roche HM, A conjugated linoleic acid-enriched beef diet attenuates lipopolysaccharide-induced inflammation in mice in part through PPARgamma-mediated suppression of toll-like receptor 4., The Journal of Nutrition, 139, (12), 2009, p2351-2357
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI

Fletcher JM, Lonergan R, Costelloe L, Kinsella K, Moran B, O'Farrelly C, Tubridy N, Mills KH, CD39+Foxp3+ regulatory T Cells suppress pathogenic Th17 cells and are impaired in multiple sclerosis., Journal of Immunology , 183, (11), 2009, p7602-7610
Journal Article; Published; Peer Reviewed; Author Profiles: FLETCHJ MILLSK OFARRECL ; DOI; URL

Becker CE, Creagh EM, O'Neill LA, Rab39a binds caspase-1 and is required for caspase-1-dependent il-1{beta} secretion, Journal of Biological Chemistry, 284, (50), 2009, p34531-34537
Journal Article; Published; Peer Reviewed; Author Profiles: ECREAGH LAONEILL ; DOI

McElligott, AM, Maginn, EN, Greene, LM, McGuckin, S, Hayat, A, Browne, PV, Butini, S, Campiani, G, Catherwood, MA, Vandenberghe, E, Williams, DC, Zisterer, DM, Lawler, M, The Novel Tubulin-Targeting Agent Pyrrolo-1,5-Benzoxazepine-15 Induces Apoptosis in Poor Prognostic Subgroups of Chronic Lymphocytic Leukemia., Cancer Research, 69, (21), 2009, p8366 - 8375
Journal Article; Published; Peer Reviewed; Author Profiles: MCELLIGA BROWNPV DWILLIMS DZISTRER ; DOI

de Roos, B, Rungapamestry, V, Ross, K, Rucklidge, G, Reid, M, Duncan, G, Horgan, G, Toomey, S, Browne, J, Loscher, CE, Mills, KH, Roche, HM, Attenuation of inflammation and cellular stress-related pathways maintains insulin sensitivity in obese type I interleukin-1 receptor knockout mice on a high-fat diet., Proteomics, 9, (12), 2009, p3244 - 3256
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI

Walsh, KP, Brady, MT, Finlay, CM, Boon, L, Mills, KH, Infection with a helminth parasite attenuates autoimmunity through TGF-beta-mediated suppression of Th17 and Th1 responses., Journal of Immunology , 183, (3), 2009, p1577 - 1586
Journal Article; Published; Peer Reviewed; Author Profiles: MILLSK COFINLAY ; DOI

Oral delivery of vaccines in, editor(s)J Fix. and V H.L. Lee , Oral Peptide and Protein Drug Delivery, New York , Marcel Dekker, 2009, [Lavelle, E.C. and O'Hagan, D.T.]
Book Chapter; Submitted; Peer Reviewed; Author Profile: LAVELLEE

Sutton, C.E., Lalor, S.J., Sweeney, C.M., Brereton, C.F., Lavelle, E.C. and Mills, K.H.G , Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity., Immunity, 31, (2), 2009, p331-341
Journal Article; Published; Peer Reviewed; Author Profiles: LAVELLEE MILLSK LALORST ; DOI

Brereton CF, Sutton CE, Lalor SJ, Lavelle EC, Mills KH., Inhibition of ERK MAPK suppresses IL-23- and IL-1-driven IL-17 production and attenuates autoimmune disease., Journal of Immunology, 183, (3), 2009, p1715-2173
Journal Article; Published; Peer Reviewed; Author Profiles: LAVELLEE MILLSK LALORST ; DOI

Sharp, F., Ruane, D., Claas, B., Creagh, E., Harris, J., Malyala, P., Singh, M., O'Hagan, D.T., Pétrilli, V., Tschopp, J., O'Neill, L.A.J. and *Lavelle, E.C, Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome., Proceedings of the National Academy of Sciences of the U.S.A, 106, (3), 2009, p870-875
Journal Article; Published; Peer Reviewed; Author Profiles: LAONEILL LAVELLEE ECREAGH ; DOI

Alexander U. Lüthi, Sean P. Cullen, Edel A. McNeela, Patrick J. Duriez, Inna S. Afonina, Clare Sheridan, Gabriela Brumatti, Rebecca C. Taylor, Kristof Kersse, Peter Vandenabeele, Ed C. Lavelle, and Seamus J. Martin, Suppression of Interleukin-33 Bioactivity through Proteolysis by Apoptotic Caspases, Immunity, 31, (1), 2009, p84-98
Journal Article; Published; Peer Reviewed; Author Profiles: MARTINSJ LAVELLEE ; DOI

Ronan G. Shaughnessy, Kieran G. Meade, Sarah Cahalane, Brenda Allan, Carla Reiman, John J. Callanan and Cliona O' Farrelly, Innate immune gene expression differentiates the early avian intestinal response between Salmonella and Campylobacter, Veterinary Immunology and Immunopathology, 132, (2-4), 2009, p191-198
Journal Article; Published; Peer Reviewed; Author Profile: OFARRECL; DOI

McDonald, Andrew G., Tipton, Keith F. and Boyce, Sinéad, Tracing metabolic pathways from enzyme data , BBA - Proteins & Proteomics, 1794, (9), 2009, p1364-1371
Journal Article; Published; Peer Reviewed; Author Profile: KTIPTON; DOI

Lyons, A, McQuillan, K, Deighan, BF, O'Reilly, JA, Downer, EJ, Murphy, AC, Watson, M, Piazza, A, O'Connell, F, Griffin, R, Mills, KH, Lynch, MA, Decreased neuronal CD200 expression in IL-4-deficient mice results in increased neuroinflammation in response to lipopolysaccharide., Brain, Behavior, and Immunity, 23, (7), 2009, p1020 - 1027
Journal Article; Published; Peer Reviewed; Author Profiles: MILLSK EDOWNER LYNCHMA ; DOI

Telford, JE, Kilbride SM and Davey GP, Complex I is rate limiting for oxygen consumption in the nerve terminal. , Journal Biological Chemistry, 284, 2009, p9109 - 9114
Journal Article; Published; Peer Reviewed; Author Profile: GDAVEY

Thanavala,Y., Lavelle, EC. and Ogra,P. , All things mucosal, Expert Reviews in Vaccines , 8, (2), 2009, p139 - 142
Journal Article; Published; Peer Reviewed; Author Profile: LAVELLEE; DOI

Lavelle, E.C., Thanavala, J. and Ogra,P. , Mucosal immunity on the banks of the Duoro, Human Vaccines, 5, (5), 2009, p1 - 3
Journal Article; Published; Peer Reviewed; Author Profile: LAVELLEE; URL

Harris, J., Hope, J. and Lavelle, E.C. , Autophagy and the immune response to TB, Transboundary and Emerging Diseases , 56, (6-7), 2009, p248-254
Journal Article; Published; Peer Reviewed; Author Profile: LAVELLEE; DOI

The role of NK cells in bacterial infection in, editor(s)Zimmer, J , Natural Killer cells - at the forefront of modern immunology, Springer, 2009, [McSharry, B and Gardiner, CM]
Book Chapter; Published; Peer Reviewed; Author Profile: GARDINEC

Day IJ, Maeda K, Paisley HJ, Mok KH, Hore PJ, Refolding of RNase A monitord by real-time photo-CIDNP NMR spectroscopy, Journal of Biomolecular NMR, 44, (2), 2009, p77 - 86
Journal Article; Published; Peer Reviewed; Author Profile: MOK1; DOI

Bernard E, Parthsarathi L, Cho M-K, Aylward K, Raab M, Daxecker H, O'Dushlaine CT, Shields DC, Devocelle M, Keyes T, Cosgrave L, O'Neill S, Mok KH, Moran N, Ligand Switching in Cell-Permeable Peptides: Manipultation of the alpha integrin signature motif, ACS Chemical Biology, 4, (6), 2009, p457 - 471
Journal Article; Published; Peer Reviewed; Author Profile: MOK1; DOI

Pettersson-Kastberg J, Aits S, Gustafsson L, Mossberg A-K, Storm P, Trulsson M, Persson F, Mok KH, Svanborg C, Can misfolded proteins be beneficial? The HAMLET case. (Review), Annals of Medicine, 41, (3), 2009, p162 - 176
Journal Article; Published; Peer Reviewed; Author Profile: MOK1; DOI

N.M. Curtin, N.T. Boyle, K.H.G. Mills and T.J. Connor, Psychological stress suppresses innate IFN-gamma production via glucocorticoid receptor activation: Reversal by the anxiolytic chlordiazepoxide., Brain Behavior and Immunity, 23, 2009, p535 - 547
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI

Mills, KH, Designer adjuvants for enhancing the efficacy of infectious disease and cancer vaccines based on suppression of regulatory T cell induction., Immunology letters, 122, (2), 2009, p108-111
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI

Boland C, Hayes PA, Santa-Maria I, Nishimura S and Kelly VP, Queuosine formation in eukaryotic tRNA occurs via a mitochondrial localized heteromeric transglycoslase. , Journal of Biological Chemistry, 284, (27), 2009, p18218-18227
Journal Article; Published; Peer Reviewed; Author Profile: KELLYVP; DOI

Orla Cunningham, Suzanne Campion, V Hugh Perry, Nicolai Sidenius, Fabian Docagne and Colm Cunningham, Microglia and the urokinase plasminogen activator receptor (uPAR) / uPA system in innate brain inflammation, GLIA, 57, (16), 2009, p1802 - 1814
Journal Article; Published; Peer Reviewed; Author Profile: CUNNINCO; DOI

Niaobh O'Donoghue, Trevor Sweeney, Robin Donagh, Kieran Clarke and Richard K. Porter , Control of Choline Oxidation in Rat Kidney Mitochondria, Biochimica Biophysica Acta (Bioenergetics), 1787, 2009, p1135 - 1139
Journal Article; Published; Peer Reviewed; Author Profile: RKPORTER; DOI; URL

Bright S.A., Greene, L.M., Greene, T.F., Campiani, G., Buitini, S., Brindisi, M., Lawler, M., Meegan, M.J., Williams, D.C. and Zisterer, D.M. , The novel pyrrolo-1,5-benzoxazepine, PBOX-21, potentiates the apoptotic efficacy of STI571 (imatinib mesylate) in human chronic myeloid leukaemia cells, Biochemical Pharmacology, 77, (3), 2009, p310-321
Journal Article; Published; Peer Reviewed; Author Profiles: DWILLIMS MMEEGAN DZISTRER MPLAWLER ; DOI; URL

Bane, F.T., Pennington, S.R., Campiani, G., Williams, D.C., Zisterer, D.M. & Mc Gee, M.M. , The microtubule-targeting agents, PBOX-6 [pyrrolobenzoxazepine 7-[(dimethylcarbamoyl)oxy]-6-(2-naphthyl)pyrrolo-[2,1-d] (1,5)-benzoxazepine] and paclitaxel, induce nucleocytoplasmic redistribution of the peptidyl-prolyl isomerases, cyclophilin A and pin1, in malignant hematopoietic cells., Journal of Pharmacology and Experimental Therapeutics, 329, 2009, p38-47
Journal Article; Published; Peer Reviewed; Author Profiles: DWILLIMS DZISTRER ; DOI; URL

Role of Toll-Like Receptors in the Innate Immune Response to RNA Viruses in, editor(s)Brasier, A.R. et al. , Cellular Signaling and Innate Immune Responses to RNA Virus Infections, ASM Press, 2009, [Keating, S.E. & Bowie A.G.]
Book Chapter; Published; Peer Reviewed; Author Profile: AGBOWIE

Characterisation of viral proteins that inhibit TLR signal transduction in, editor(s)O'Neill, L.A.J and McCoy, C. , Toll-Like Receptors, Methods of Molecular Biology, Humana Press, 2009, [Stack, J & Bowie, A.G.]
Book Chapter; Published; Peer Reviewed; Author Profiles: AGBOWIE LAONEILL

Uncovering novel gene function in TLR signalling using siRNA in, editor(s)O'Neill, L.A.J and McCoy, C. , Toll-Like Receptors, Methods of Molecular Biology, Humana Press, 2009, [Carty, M., Keating, S. & Bowie, A.G. ]
Book Chapter; Published; Peer Reviewed; Author Profiles: AGBOWIE LAONEILL

Kalverda AP, Thompson GS, Vogel A, Schröder M, Bowie AG, Khan AR & Homans SW, Poxvirus K7 protein adopts a Bcl-2 fold: Biochemical mapping of its interactions with human DEAD box RNA helicase DDX3., Journal of Molecular Biology, 385, (3), 2009, p843-853
Journal Article; Published; Peer Reviewed; Author Profiles: AMIRRAFK AGBOWIE ; DOI; URL

Recacha R, Boulet A, Jollivet F, Monier S, Houdusse A, Goud B & Khan AR , Structural basis for recruitment of Rab6-Interacting Protein 1 to Golgi via a RUN domain., Structure, 17, (1), 2009, p21-30
Journal Article; Published; Peer Reviewed; Author Profile: AMIRRAFK; DOI; URL

Nomenclature and Potential Functions of Copper Amine Oxidases in, editor(s)Giovanni Floris and Bruno Mondovi , Copper Amine Oxidases: Structures, Catalytic Mechanisms and Role in Pathophysiology, CRC Press, 2009, [S. Boyce, K. F. Tipton, M. I. O'Sullivan, G. P. Davey, M. Motherway Gildea, A. G. McDonald, A. Olivieri, and J. O'Sullivan]
Book Chapter; Published; Peer Reviewed; Author Profiles: GDAVEY MISULLVN

Onnis V, Kinsella GK, Carta G, Fayne D, Lloyd DG., Rational ligand based drug design and structure-activity relationship studies in the ligand-binding domain of the glucocorticoid receptor á, Future Medicinal Chemistry, 1, (2), 2009, p345 - 359
Journal Article; Published; Peer Reviewed; Author Profile: FAYNED

O'Neill LAJ and McCoy C, Toll-like receptor protocols. Methods in Molecular Medicine Series, 517, New Jersey USA , Humana Press, 2009
Book; Published; Peer Reviewed; Author Profile: LAONEILL

Palsson-McDermott E, Doyle S, McGettrick A, Hardy M, Husebye H, Banahan K, Gong M, Golenbock , Espevik T and O'Neill LAJ, TAG: a GOLD domain-containing splice variant of TRAM that negatively regulates the MyD88-independent pathway in TLR4 signaling, Nature Immunology, 10, 2009, p579 - 586
Journal Article; Published; Peer Reviewed; Author Profiles: PALSSONE DOYLES8 LAONEILL BANAHANK MCGETTRA ; DOI

Sheedy FJ, O'Neill LA., Adding fuel to fire: microRNAs as a new class of mediators of inflammation., Annals of the Rheumatic Diseases, 67 , (Suppl 3), 2009, piii50 - iii55
Journal Article; Published; Peer Reviewed; Author Profiles: FSHEEDY LAONEILL ; DOI; URL

Freinbichler, W., Tipton, K.F., Della Corte, L. and Linert, W. , Mechanistic aspects of the Fenton reaction under conditions approximated to the extracellular fluid. , Journal of Inorganic Biochemistry, 103, (1), 2009, p28 - 34
Journal Article; Published; Peer Reviewed; Author Profile: KTIPTON

Downing, T, Lynn, DJ, Connell, S, Lloyd, AT, Bhuiyan, AF, Silva, P, Naqvi, AN, Sanfo, R, Sow, RS, Podisi, B, O'Farrelly, C, Hanotte, O, Bradley, DG, Contrasting evolution of diversity at two disease-associated chicken genes., Immunogenetics, 61, (1), 2009, p303 - 314
Journal Article; Published; Peer Reviewed; Author Profiles: DBRADLEY OFARRECL ; DOI

Keating, SE, Bowie, AG, The role of non-degradative ubiquitination in interleukin-1 and Toll-like receptor signalling., The Journal of Biological Chemistry, 284, (13), 2009, p8211 - 8215
Journal Article; Published; Peer Reviewed; Author Profile: AGBOWIE; DOI; URL

David J. Sanderson, Colm Cunningham, Robert, M.J. Deacon, David, M. Bannerman, V. Hugh Perry, & J. Nicholas P. Rawlins., A double dissociation between the effects of sub-pyrogenic systemic inflammation and hippocampal lesions on learning, Behavioural Brain Research, 201, (1), 2009, p103 - 111
Journal Article; Published; Peer Reviewed; Author Profile: CUNNINCO; DOI

N.M. Curtin, K.H.G. Mills and T.J. Connor, Psychological stress increases expression of IL-10 and its homolog IL-19 via beta-adrenoceptor activation: Reversal by the anxiolytic chlordiazepoxide, Brain Behavior and Immunity, 23, (3), 2009, p371 - 379
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI

Kieran G. Meade, Rowan Higgs, Andrew T. Lloyd, Seamus Giles and Cliona O'Farrelly, Differential antimicrobial peptide gene expression patterns during early chicken embryological development , Developmental & Comparative Immunology, 33, (4), 2009, p516-524
Journal Article; Published; Peer Reviewed; Author Profile: OFARRECL; DOI; URL

McDonald, A., Boyce, S., and Tipton, K.F. , ExplorEnz: the primary source of the IUBMB enzyme list, Nucleic Acids Research, 37, (Database Issue), 2009, pD593 - D597
Journal Article; Published; Peer Reviewed; Author Profile: KTIPTON

Cunningham, C., Campion, S., Lunnon, K., Deacon, R.M.J, Rawlins, J.N.P. and Perry, V.H., Systemic inflammation superimposed on chronic neurodegeneration induces acute behavioural and cognitive changes and accelerates neurological decline. , Biological Psychiatry , 65, (4), 2009, p305 - 312
Journal Article; Published; Peer Reviewed; Author Profile: CUNNINCO; DOI

Murphy, James E.J. and Porter, Richard K. , The Control of Oxidative Phosphorylation in the Adrenal Gland Cell Line (Y1), Advances in Experimental Medicine and Biology, 645, 2009, p35 - 41
Journal Article; Published; Peer Reviewed; Author Profile: RKPORTER; URL