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Publications

Below is the list of peer and non peer publications from the School of Biochemistry and Immunology.

Show: AllPeer ReviewedNon Peer Reviewed
100 publications from 2008

Sinclair, L.V. and Finlay, D. and Feijoo, C. and Cornish, G.H. and Gray, A. and Ager, A. and Okkenhaug, K. and Hagenbeek, T.J. and Spits, H. and Cantrell, D.A., Errattum: Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking (Nature Immunology (2008) vol. 9(6) (513-521)), Nature Immunology, 9, (6), 2008, p692
Journal Article; Published; Peer Reviewed; Author Profile: FINLAYD; DOI; URL

Porter, R.K., From the organizers, Biochimica et Biophysica Acta - Bioenergetics, 1777, (SUPPL.), 2008
Journal Article; Published; Peer Reviewed; Author Profile: RKPORTER; DOI; URL

Porter, R.K., Uncoupling protein 1: A short-circuit in the chemiosmotic process, Journal of Bioenergetics and Biomembranes, 40, (5), 2008, p457-461
Journal Article; Published; Peer Reviewed; Author Profile: RKPORTER; DOI; URL

Richard K. Porter, Preface: From the Organizers, European Bioenergetics Conference (EBEC) 2008, Trinity College Dublin, July, edited by Richard K. Porter , 2008
Meeting Abstract; Published; Peer Reviewed; Author Profile: RKPORTER; URL

Richard K. Porter, "Choline Oxidation in Kidney Mitochondria" , COST meeting, University of Stockholm, Sweden., May , 2008, COST Mitofood
Invited Talk; Published; Peer Reviewed; Author Profile: RKPORTER

Richard K. Porter, "The Role Uncoupling Proteins in Immune Function" , European Bioenergetics Conference (EBEC) July 2008 Dublin. , Dublin, Ireland, July, 2008, European Bioenergetics Conference (EBEC)
Invited Talk; Published; Peer Reviewed; Author Profile: RKPORTER

Ryan, T.J., Emes, R.D., Grant, S.G.N., Komiyama, N.H., Evolution of NMDA receptor cytoplasmic interaction domains: Implications for organisation of synaptic signalling complexes, 9, 2008
Journal Article; Published; Peer Reviewed; Author Profile: TRYAN6

Biochimica Biophysica Acta (Bioenergetics), Netherlands, Elsevier, [eds.], 2008-2022
Editorial Board; Published; Peer Reviewed; Author Profile: RKPORTER; URL

Budanov AV, Karin M, p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling., Cell, 134, (3), 2008, p451 - 460
Journal Article; Published; Peer Reviewed; Author Profile: BUDANOVA; DOI

Davies D, Meade KG, Herath S, Eckersall PD, Gonzalez D, White JO, Conlan RS, O'Farrelly C, Sheldon IM, Toll-like receptor and antimicrobial peptide expression in the bovine endometrium., Reproductive biology and endocrinology : RB&E, 6, 2008, p53
Journal Article; Published; Peer Reviewed; Author Profile: OFARRECL; DOI

Watkins, AJ, Ursell, E, Panton, R, Papenbrock, T, Ollis, LH, Cunningham, C, Wilkins, A, Perry, VH, Sheth, B, Kwong, WY, Eckert, JJ, Wild, AE, Hanson, MA, Osmond, C, Fleming, TP, Adaptive responses by mouse early embryos to maternal diet protect fetal growth but predispose to adult onset disease, BIOLOGY OF REPRODUCTION, 78, (2), 2008, p299-306
Journal Article; Published; Peer Reviewed; Author Profile: CUNNINCO; DOI

Watkins, AJ, Wilkins, A, Cunningham, C, Perry, VH, Seet, MJ, Osmond, C, Eckert, JJ, Torrens, C, Cagampang, FRA, Cleal, J, Gray, WP, Hanson, MA, Fleming, TP, Low protein diet fed exclusively during mouse oocyte maturation leads to behavioural and cardiovascular abnormalities in offspring, JOURNAL OF PHYSIOLOGY-LONDON, 586, (8), 2008, p2231-2244
Journal Article; Published; Peer Reviewed; Author Profile: CUNNINCO; DOI

Stevenson NJ, Ryan EJ, Keogh CA, Lloyd AT, Cormican P, Hegarty JE, O'Farrelly C. , Hepatitis C virus (HCV) regulates signal transducer and activator of transcription (STAT) protein expression to escape interferon-alpha (IFN-alpha) responses. , Immunology, 125, (1), 2008, pp71
Conference Paper; Published; Non Peer Reviewed; Author Profile: STEVENNJ

McLoughlin RM, Lee JC, Kasper DL, Tzianabos AO, IFN-gamma regulated chemokine production determines the outcome of Staphylococcus aureus infection., Journal of immunology (Baltimore, Md. : 1950), 181, (2), 2008, p1323-32
Journal Article; Published; Peer Reviewed; Author Profile: MCLOUGRM

Fielding CA, McLoughlin RM, McLeod L, Colmont CS, Najdovska M, Grail D, Ernst M, Jones SA, Topley N, Jenkins BJ, IL-6 regulates neutrophil trafficking during acute inflammation via STAT3., Journal of immunology (Baltimore, Md. : 1950), 181, (3), 2008, p2189-95
Journal Article; Published; Peer Reviewed; Author Profile: MCLOUGRM

Sinclair LV., Finlay D., Fejoo C., Cornish GH., Gray A., Ager A., Okkenhaug K., Hagenbeek TJ., Spits H., Cantrell DA, Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking, Nature Immunology, 9, (5), 2008, p513 - 521
Journal Article; Published; Peer Reviewed; Author Profile: FINLAYD; DOI; URL

Sauer S, Bruno L, Hertweck A, Finlay D, Leleu M, Spivakov M, Knight ZA, Cobb BS, Cantrell D, O'Connor E, Shokat KM, Fisher AG, Merkenschlager M., T cell receptor signaing controls Foxp3 expression via PI3K, Akt and mTOR., PNAS, 105, (22), 2008, p7797 - 7802
Journal Article; Published; Peer Reviewed; Author Profile: FINLAYD; DOI; URL

Martin Caffrey, On the Mechanism of Membrane Protein Crystallization in Lipidic Mesophases, Crystal Growth and Design, 8, (12), 2008, p4244-4254
Journal Article; Published; Peer Reviewed; Author Profile: MCAFFRE; DOI

Cherezov V, Höfer N, Szebenyi DM, Kolaj O, Wall JG, Gillilan R, Srinivasan V, Jaroniec CP, Caffrey M, Insights into the mode of action of a putative zinc transporter CzrB in Thermus thermophilus., Structure (London, England : 1993), 16, (9), 2008, p1378-88
Journal Article; Published; Peer Reviewed; Author Profile: MCAFFRE; DOI

Cherezov V, Liu W, Derrick JP, Luan B, Aksimentiev A, Katritch V, Caffrey M, In meso crystal structure and docking simulations suggest an alternative proteoglycan binding site in the OpcA outer membrane adhesin., Proteins, 71, (1), 2008, p24-34
Journal Article; Published; Peer Reviewed; Author Profile: MCAFFRE; DOI

Mok KH (Inventor), Mok KH (Assignee), A pharmaceutical composition comprising a retro-inverso isomer peptide, 2008, US Patent No. 7,314,867 (1 Jan 2008)
Patent; Published; Peer Reviewed; Author Profile: MOK1

L. J.Smith, S. Browne, A. J. Mulholland and T. J. Mantle, Computational and experimental studies on the catalytic mechanism of biliverdin IXβ reductase, Biochemical Journal, 411, 2008, p475-484
Journal Article; Published; Peer Reviewed; Author Profile: TMANTLE; DOI

Coustou V, Brian M, Guegan F, Riviere L, Plazolles N, Nolan D, Barrett MP, Franconi JM, Bringaud F., Glucose-induced Remodeling of Intermediary and Energy Metabolism in Procyclic Trypanosoma brucei, The Journal of Biological Chemistry, 283, (24), 2008, p16342-16354
Journal Article; Published; Peer Reviewed; Author Profile: DENOLAN; DOI

Derek P. Nolan and Jose A. Garcia-Salcedo, Loss of actin does not affect export of newly synthesized proteins to the surface of Trypanosoma brucei, Molecular and Biochemical Parasitology, 157, (2), 2008, p233-235
Journal Article; Published; Peer Reviewed; Author Profile: DENOLAN; DOI

Alison E. Adams, Orla Hanrahan, Derek N. Nolan, H. Paul Voorheis, Padraic Fallon and Richard K. Porter, Images of mitochondrial UCP 1 in mouse thymocytes using confocal microscopy , Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1777, (2), 2008, p115 - 117
Journal Article; Published; Peer Reviewed; Author Profiles: PFALLON DENOLAN RKPORTER ; DOI

Hayes, J., Li, S., Anwyl, R., Rowan, M.J., A role for protein kinase A and protein kinase Mζ in muscarinic acetylcholine receptor-initiated persistent synaptic enhancement in rat hippocampus in vivo, Neuroscience , 151, (2), 2008, p604-612
Journal Article; Published; Peer Reviewed; Author Profile: MROWAN; DOI

Rowan AG, Fletcher JM, Ryan EJ, Moran B, Hegarty JE, O'Farrelly C and Mills KHG, Hepatitis C virus-specific Th17 cells are suppressed by virus-induced TGF-beta, Journal of Immunology, 181, (7), 2008, p4485 - 4494
Journal Article; Published; Peer Reviewed; Author Profiles: MORANBA FLETCHJ MILLSK ; URL

Suzuki T, Kelly VP, Motohashi H, Nakajima O, Takahashi S, Nishimura S, Yamamoto M, Deletion of the selenocysteine tRNA gene in macrophages and liver results in compensatory gene induction of cytoprotective enzymes by Nrf2., Journal of Biological Chemistry, 283, (4), 2008, p2021-2030
Journal Article; Published; Peer Reviewed; Author Profile: KELLYVP; DOI

IL-10 and TGF-beta-producing regulatory T cells in infection in, editor(s)Shuiping Jiang , Regulatory cells and Clinical Application, Springer Science and Business Media, LLC , 2008, pp423 - 453, [Dunne PJ, Rowan A, Fletcher JM and KHG Mills]
Book Chapter; Published; Peer Reviewed; Author Profiles: MILLSK FLETCHJ

Van Baarle, D., Nanlohy, N.M., Otto, S., Plunkett, F.J., Fletcher, J.M., Akbar, A.N., Progressive telomere shortening of Epstein-Barr virus-specific memory T cells during HIV infection: Contributor to exhaustion, Journal of Infectious Diseases, 198, (9), 2008, p1353-1357
Journal Article; Published; Peer Reviewed; Author Profile: FLETCHJ; DOI

Kilbride SM, Telford JE, Davey GP, Age-related changes in H2O2 production and bioenergetics in rat brain synaptosomes, Biochim Biophys Acta Bioenergetics, 1777, 2008, p783 - 788
Journal Article; Published; Peer Reviewed; Author Profile: GDAVEY

Upadhyay R and Davey GP , Complex I and energy thresholds in the brain, Biochim Biophys Acta Bioenergetics, 1777, 2008, p777 - 782
Journal Article; Published; Peer Reviewed; Author Profile: GDAVEY

Kilbride SM, Telford, JE, Tipton, KF and Davey GP, Partial inhibition of complex I activity increases Ca2+-independent glutamate release rates from synaptosomes. , Journal of Neurochemistry, 106, 2008, p826 - 834
Journal Article; Published; Peer Reviewed; Author Profile: GDAVEY

Athie-Morales, O'Connor GM and Gardiner CM, Activation of human NK cells by the bacterial pathogen-associated molecular pattern, muramyl dipeptide, Journal of Immunology, 180, (6), 2008, p4082 - 4089
Journal Article; Published; Peer Reviewed; Author Profile: GARDINEC

Gardiner CM, Killer cell immunoglobulin-like receptors on NK cells: the how, where and why, International Journal of Immunogenetics, 35, (1), 2008, p1 - 8
Journal Article; Published; Peer Reviewed; Author Profile: GARDINEC

Verma NK, Dempsey E, Conroy J, Olwell P, Mcelligott AM, Davies AM, Kelleher D, Butini S, Campiani G, Williams DC, Zisterer DM, Lawler M, Volkov Y., A new microtubule-targeting compound PBOX-15 inhibits T-cell migration via post-translational modifications of tubulin., Journal of Molecular Medicine, 86, (4), 2008, p457-469
Journal Article; Published; Peer Reviewed; Author Profiles: DWILLIMS DZISTRER MPLAWLER ; DOI

Mills, KH, Induction, function and regulation of IL-17-producing T cells., European Journal of Immunology, 38, (10), 2008, p2636-2649
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI

Meegan, M.J., Carr, M., Knox, A.J.S., Zisterer, D.M. & Lloyd, D.G., Beta-Lactam type molecular scaffolds for antiproliferative activity: Synthesis and cytotoxic effects in breast cancer cells., Journal of Enzyme Inhibition and Medicinal Chemistry, 23, (5), 2008, p668-685
Journal Article; Published; Peer Reviewed; Author Profiles: MMEEGAN DZISTRER ; DOI; URL

Barrett, I., Meegan, M.J., Hughes, R.B., Carr, M., Knox, A.J.S. Artemenko, N., Golfis, G., Zisterer, D.M. & Lloyd, D.G., Synthesis, biological evaluation, structural-activity relationship, and docking study for a series of benzoxepin-derived estrogen receptor modulators., Bioorganic & Medicinal Chemistry, 16, (21), 2008, p9554-9973
Journal Article; Published; Peer Reviewed; Author Profiles: MMEEGAN DZISTRER ; DOI; URL

Toll-like receptor 3 in, New Drugs and Targets for Respiratory Diseases, Prous Science, 2008, [Carty, M. & Bowie, A.G. ]
Book Chapter; Published; Peer Reviewed; Author Profile: AGBOWIE

Modulation of Innate Immune Signalling Pathways by Viral Proteins in, editor(s)Fallon, P. , Pathogen-Derived Immunomodulatory Molecules, 2008, [Mulhern, O., Harrington, B. & Bowie, A.G.]
Book Chapter; Published; Peer Reviewed; Author Profile: AGBOWIE

Bowie, A.G., Insights from vaccinia virus into Toll-like receptor signalling proteins and their regulation by ubiquitin: role of IRAK-2, Biochemistry Society Transactions, 36, (3), 2008, pp449-452
Conference Paper; Published; Non Peer Reviewed; Author Profile: AGBOWIE; URL

Adams AE, Carroll AM, Fallon PG, Porter RK., Mitochondrial uncoupling protein 1 expression in thymocytes., Biochimica et Biophysica Acta (BBA) - Bioenergetics , 1777, (7-8), 2008, p772 - 776
Journal Article; Published; Peer Reviewed; Author Profiles: RKPORTER PFALLON ; DOI

Kenny EF, O'Neill LA., Signalling adaptors used by Toll-like receptors: an update., Cytokine, 43, (3), 2008, p342 - 349
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

O'Neill LA, The interleukin-1 receptor / Toll-like receptor superfamily: ten years of progress, Immunological Reviews, 226, (1), 2008, p10 - 18
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Kotera, M., McDonald, A.G., Boyce, S. and Tipton, K.F. , Eliciting possible reaction equations and metabolic pathways involving orphan metabolites. , Journal of Chemical Information and Modeling. , 48, (12), 2008, p2335 - 2349
Journal Article; Published; Peer Reviewed; Author Profile: KTIPTON

Schröder, M, Baran, M, Bowie, AG, Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKepsilon-mediated IRF activation., The EMBO journal, 27, (15), 2008, p2147 - 2157
Journal Article; Published; Peer Reviewed; Author Profile: AGBOWIE; DOI; URL

Bowie, AG, Unterholzner, L, Viral evasion and subversion of pattern-recognition receptor signalling., Nature Reviews Immunology, 8, (12), 2008, p911 - 922
Journal Article; Published; Peer Reviewed; Author Profile: AGBOWIE; DOI; URL

Mills, K.H.G. , TLR9 Turns the Tide on Treg Cells , Immunity, 28, (4), 2008, 518-520
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI; URL

Hickey, F.B., Brereton, C.F., Mills, K.H.G. , Adenylate cycalse toxin of Bordetella pertussis inhibits TLR-induced IRF-1 and IRF-8 activation and IL-12 production and enhances IL-10 through MAPK activation in dendritic cells , Journal of Leukocyte Biology , 84, (1), 2008, p234-243
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI

Toomey, D., Conroy, H., Jarnicki, A.G., Higgins, S.C., Sutton, C., Mills, K.H.G. , Therapeutic vaccination with dendritic cells pulsed with tumor-derived Hsp70 and a COX-2 inhibitor induces protective immunity against B16 melanoma , Vaccine, 26, (27-28), 2008, p3540-3549
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI; URL

Rosen, HR, Doherty, DG, Madrigal-Estebas, L, O'Farrelly, C, Golden-Mason, L, Pretransplantation CD56(+) innate lymphocyte populations associated with severity of hepatitis C virus recurrence., Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 14, (1), 2008, p31 - 40
Journal Article; Published; Peer Reviewed; Author Profiles: DOHERTDE OFARRECL ; DOI; URL

Cormican, P, Meade, KG, Cahalane, S, Narciandi, F, Chapwanya, A, Lloyd, AT, O'Farrelly, C, Evolution, expression and effectiveness in a cluster of novel bovine beta-defensins., Immunogenetics, 60, (3-4), 2008, p147-156
Journal Article; Published; Peer Reviewed; Author Profile: OFARRECL; DOI; URL

Golden-Mason, L, Madrigal-Estebas, L, McGrath, E, Conroy, MJ, Ryan, EJ, Hegarty, JE, O'Farrelly, C, Doherty, DG, Altered natural killer cell subset distributions in resolved and persistent hepatitis C virus infection following single source exposure., Gut, 57, (8), 2008, p1121-8
Journal Article; Published; Peer Reviewed; Author Profiles: DOHERTDE OFARRECL MECONROY ; DOI; URL

Meade, KG, Cahalane, S, Narciandi, F, Cormican, P, Lloyd, AT, O'Farrelly, C, Directed alteration of a novel bovine beta-defensin to improve antimicrobial efficacy against methicillin-resistant Staphylococcus aureus (MRSA)., International journal of antimicrobial agents, 32, (5), 2008, p392-397
Journal Article; Published; Peer Reviewed; Author Profile: OFARRECL; DOI; URL

Meade, KG, Gormley, E, O'Farrelly, C, Park, SD, Costello, E, Keane, J, Zhao, Y, MacHugh, DE, Antigen stimulation of peripheral blood mononuclear cells from Mycobacterium bovis infected cattle yields evidence for a novel gene expression program., BMC genomics, 9, (447), 2008
Journal Article; Published; Peer Reviewed; Author Profile: OFARRECL; DOI; URL

Taylor, C.F., Field, D., Sansone, S.A., Aerts, J., Apweiler, R., Ashburner, M., Ball, C.A., Binz, P.A., Bogue, M., Booth, T., Brazma, A., Brinkman, R.R., Clark, M.A., Deutsch, E.W., Fiehn, O., Fostel, J., Ghazal, P., Gibson, F., Gray, T., Grimes, G., Hancock, J.M., Hardy, N.W., Hermjakob, H., Julian, R.K. Kane, M., Kettner, C., Kinsinger, C., Kolker, E., Kuiper, M., Novère N.L., Leebens-Mack, J., Lewis, S.E., Lord, P., Mallon, A.M., Marthandan, N., Masuya, H., McNally, R., Mehrle, A., Morrison, N., Orchard, S., Quackenbush, J., Reecy, J.M., Robertson, D.G., Rocca-Serra, P., Rodriguez, H., Rosenfelder, H., Santoyo-Lopez, J., Scheuermann, R.H., Schober, D., Smith, B., Snape, J., Stoeckert, C.J., Tipton, K.F., Sterk, P., Untergasser, A., Vandesompele, J. and Wiemann, S. , Promoting coherent minimum reporting requirements for biological and biomedical investigations: The MIBBI project, Nature Biotechnology, 26, (8), 2008, p889 - 896
Journal Article; Published; Peer Reviewed; Author Profile: KTIPTON

Ballini, C., Della Corte, L., Pazzagli, M., M.A, Colivicchi, M.A., Pepeu, G.. Tipton, K.F. and Giovannini, M.G. , Extracellular levels of brain aspartate, glutamate and GABA during an inhibitory avoidance response in the rat, Journal of Neurochemistry, 106, (3), 2008, p1035 - 1043
Journal Article; Published; Peer Reviewed; Author Profile: KTIPTON

Kilbride, S.M., Telford, J.E., Tipton, K.F. and Davey, G.P., Partial inhibition of complex I activity increases Ca2+-independent glutamate release rates from depolarized synaptosomesPartial inhibition of complex I activity increases Ca2+-independent glutamate release rates from depolarized synaptosomes, Journal of Neurochemistry, 106, (2), 2008, p826 - 834
Journal Article; Published; Peer Reviewed; Author Profile: KTIPTON

Cornally, D., Mee, B., MacDonaill, C., Tipton, K.F., Kelleher, D., Windle, H.J. and Henehan, G.T.M., Aldo-keto reductase from Helicobacter pylori - role in adaptation to growth at acid pH, FEBS Journal, 275, (12), 2008, p3041 - 3050
Journal Article; Published; Peer Reviewed; Author Profile: KTIPTON

Freinbichler, W., Bianchi, L., Colivicchi, M.A., Ballini, C., Tipton, K.F., Linert, W. and Della Corte, L. , The detection of hydroxyl radicals in vivo, Journal of Inorganic Biochemistry, 102, (5-6), 2008, p1329 - 1333
Journal Article; Published; Peer Reviewed; Author Profile: KTIPTON

Sanz, E., Quintana, A., Battaglia, V., Toninello, A., Hidalgo, J., Ambrosio, S., Valoti, M., Marco, J.L., Tipton, K.F., Unzeta, M.. ., Anti-apoptotic effect of Mao-B inhibitor PF9601N [N-(2-propynyl)-2-(5-benzyloxy-indolyl) methylamine] is mediated by p53 pathway inhibition in MPP(+)-treated SH-SY5Y human dopaminergic cells, Journal of Neurochemistry, 105, (6), 2008, p2404 - 2417
Journal Article; Published; Peer Reviewed; Author Profile: KTIPTON

From the enzyme list to pathways and back again in, editor(s)M.G. Hicks & C. Kettner , Proceedings of the 3rd International Beilstein Workshop on Experimental Standard Conditions of Enzyme Characterizations, Frankfurt, Germany, Beilstein Institut, 2008, pp109 - 122, [McDonald, A.G., Tipton, K.F. and Boyce, S. ]
Book Chapter; Published; Peer Reviewed; Author Profile: KTIPTON

Freinbichler, W., Colivicchi, M.A., Fattori, M., Ballini, C., Tipton, K.F., Linert, W. and Della Corte, L., Validation of a robust and sensitive method for detecting hydroxyl radical formation together with evoked neurotransmitter release in brain microdialysis, Journal of Neurochemistry, 105, (3), 2008, p738 - 749
Journal Article; Published; Peer Reviewed; Author Profile: KTIPTON

Kotera, M., McDonald, A.G., Boyce, S. and Tipton, K.F. , Functional Group and Substructure Searching as a Tool in Metabolomics, PLoS ONE , 3, (2, e1537), 2008, p1-8
Journal Article; Published; Peer Reviewed; Author Profiles: KTIPTON AMCDONLD ; DOI; URL

Palin, P., Cunningham, C., Forse, P., V. Hugh Perry and Nick Platt., Systemic inflammation switches the inflammatory cytokine profile in CNS Wallerian degeneration, Neurobiology of Disease, 30, 2008, p19 - 29
Journal Article; Published; Peer Reviewed; Author Profile: CUNNINCO; DOI

Ayodeji A Asuni, Colm Cunningham, Piranvhan Vigneswaran, Hugh V Perry and Vincent O'Connor. , Unaltered SNARE complex formation in an in vivo model of Prion disease, Brain Research, 1233, 2008, p1 - 7
Journal Article; Published; Peer Reviewed; Author Profile: CUNNINCO; DOI

Alasdair MacLullich, Sophia de Rooij, Thomas Miller, Karen Ferguson and Colm Cunningham. , Unravelling the pathophysiology of delirium: a focus on aberrant stress responses. , Journal of Psychosomatic Research, 65, (3), 2008, p229 - 238
Journal Article; Published; Peer Reviewed; Author Profile: CUNNINCO; DOI

Cunningham, C and Sanderson, D., Malaise in the water Maze: untangling the effects of IL-1b and LPS on learning and memory, Brain Behavior and Immunity, 22, (8), 2008, p1117 - 1127
Journal Article; Published; Peer Reviewed; Author Profile: CUNNINCO; DOI

Meade KG, Gormley E, O'Farrelly C, Park SD, Costello E, Keane J, Zhao Y, Machugh DE., Antigen stimulation of peripheral blood mononuclear cells from Mycobacterium bovis infected cattle yields evidence for a novel gene expression program., BMC Genomics, 29, (9), 2008, p447-
Journal Article; Published; Peer Reviewed; Author Profiles: OFARRECL JOSEPHMK ; DOI

Andrew G. McDonald; Sinead Boyce; Keith F. Tipton, ExplorEnz: the primary source of the IUBMB enzyme list, Nucleic Acids Research, 2008
Journal Article; Published; Peer Reviewed; Author Profile: AMCDONLD; DOI; URL

Davey G. & Porter Richard K., Bioenergetics: Going from Strength to strength, Biochimica Biophysica Acta (Bioenergetics), EBEC 2008, Trinity College Dublin, 19-24 July 2008, edited by Richard K. Porter & Gavin Davey , 1777, (7-8), Elsevier, 2008, pp549 - 549
Meeting Abstract; Published; Peer Reviewed; Author Profile: RKPORTER

Porter Richard K., Preface, EBEC Short reports, EBEC 2008, Trinity College Dublin, 19-24 July 2008, edited by Richard K. Porter & Gavin Davey , 1777, Elsevier, 2008, ppS1-
Meeting Abstract; Published; Peer Reviewed; Author Profiles: OSULLICA RKPORTER

Dlaskova, A. & Porter R.K., regulation of H2O2 generation by uncoupling protein UCP 1 in BAT and thymus mitochondria, EBEC 2008 Short reports, EBEC 2008, Trinity College Dublin, 19-24 July 2008, edited by Richard K. Porter & Gavin Davey , 1777, Elsevier, 2008, ppS65-
Meeting Abstract; Published; Peer Reviewed; Author Profile: RKPORTER; URL

Clarke K.J. & Porter R.K. , The effect of preserving covalent modification of mitochondria by phosphorylation on oxygen consumption by mitochondria isolated from brown adipose tissue and thymus, EBEC 2008 Short Reports, EBEC 2008, Trinity College Dublin, 19-24 July 2008, edited by Richard K. Porter & Gavin Davey , 1777, Elsevier, 2008, ppS54-
Meeting Abstract; Published; Peer Reviewed; Author Profile: RKPORTER; URL

Porter R.K. & Fallon P.G., mitochondrial UCP 1 and thymus function, EBEC 2008 Short Reports, EBEC 2008, Trinity College Dublin, 19-24 July 2008, edited by Richard K. Porter & Gavin Davey , 1777, 2008, ppS34-
Meeting Abstract; Published; Peer Reviewed; Author Profile: RKPORTER; URL

Adams A.E. Porter R.K. , Apoptosis in thymocytes from UCP 1 wild-type and UCP 1 knock-out mice, EBEC 2008 Short reports, EBEC 2008, Trinity College Dublin, 19-24July 2008, edited by Richard K. Porter & Gavin Davey , 1777, 2008, ppS44-
Meeting Abstract; Published; Peer Reviewed; Author Profile: RKPORTER; URL

Porter Richard K., uncoupling protein 1: A short-circuit in the Chemiosmotic process, the Journal of Bioenergetics and Biomembranes, 40, 2008, p457 - 461
Journal Article; Published; Peer Reviewed; Author Profile: RKPORTER; URL

Adams, Alison E., Carroll, Audrey M., Fallon, Padraic G. & Porter, Richard K., Mitochondrial uncoupling protein 1 expression in thymocytes, Biochimica Biophysica Acta (Bioenergetics), 1777, (7-8), 2008, p772 - 775
Journal Article; Published; Peer Reviewed; Author Profile: RKPORTER; URL

Carroll, Audrey M., Porter, Richard K. & Morrice, Nicolas A., Identification of serine phosphorylation in mitochondrial uncoupling protein 1, Biochimica Biophysica Acta (Bioenergetics), 1777, (7-8), 2008, p1060 - 1065
Journal Article; Published; Peer Reviewed; Author Profile: RKPORTER; URL

O'Neill LAJ , When signalling pathways collide: positive and negative regulation of Toll-like receptor signalling, Immunity , 29, (1), 2008, p12 - 20
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

O'Neill LAJ, Immunology. How frustration leads to inflammation., Science, 320, (5876), 2008, p619-20
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

O'Neill LA, 'Fine tuning' TLR signaling, Nat Immunol. , 9, (5), 2008, p459-61
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

O'Neill LA , Primer: Toll-like receptor signaling pathways--what do rheumatologists need to know?, Nat Clin Pract Rheumatol., 4, (6), 2008, p319-27
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI

Chau TL, Gioia R, Gatot JS, Patrascu F, Carpentier I, Chapelle JP, O'Neill L, Beyaert R, Piette J, Chariot A, Are the IKKs and IKK-related kinases TBK1 and IKK-varepsilon similarly activated?, Trends Biochem Sci, 33, (4), 2008, p171-80
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

McCoy CE, O'Neill LA., The role of toll-like receptors in macrophages., Front Biosci., 1, (13), 2008, p62-70
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Piao W, Song C, Chen H, Wahl LM, Fitzgerald KA, O'Neill LA, Medvedev AE., Tyrosine phosphorylation of MyD88 adapter-like (Mal) is critical for signal transduction and blocked in endotoxin tolerance, Journal of Biological Chemistry, 283, (6), 2008, p3109-19
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI

Brikos C, O'Neill LA. , Signalling of toll-like receptors., Handb Exp Pharmacol., 183, 2008, p21-50
Review; Published; Peer Reviewed; Author Profile: LAONEILL

Sheedy FJ, Marinou I, O'Neill LA, Wilson AG., The Mal/TIRAP S180L and TLR4 G299D polymorphisms are not associated with susceptibility to or severity of rheumatoid arthritis., Ann Rheum Dis., 2008
Journal Article; Published; Peer Reviewed; Author Profiles: FSHEEDY LAONEILL ; DOI; URL

Costelloe C, Watson M, Murphy A, McQuillan K, Loscher C, Armstrong ME,, IL-1F5 mediates anti-inflammatory activity in the brain through induction, J Neurochem, 105, (5), 2008, p1960-1969
Journal Article; Published; Peer Reviewed; Author Profiles: LAONEILL MILLSK ARMSTRP LYNCHMA ; DOI; URL

McCoy CE, Carpenter S, Palsson-McDermott EM, Gearing J, O'Neill, LA, Glucocorticoids inhibit IRF3 phosphorylation in response to Toll-like, The Journal of Biological Chemistry, 283, 2008, p14277-14285
Journal Article; Published; Peer Reviewed; Author Profiles: LAONEILL PALSSONE ; DOI

O'Neill L.A., Bacteria fight back against Toll-like receptors., Nat Med., 14, (4), 2008, p370-372
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

O'Neill, L.A., Innate Immunity: Squelching Anti-Viral Signalling with NLRXI, Curr Biol, 18, (7), 2008, pR302-R304
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Bowie, A.G., TRIM-ing down Tolls, Nature Immunology, 9, (4), 2008, p348 - 350
Journal Article; Published; Peer Reviewed; Author Profile: AGBOWIE; DOI; URL

Jarnicki, AJ, Conroy, H. Brereton, C, Donnelly, G., Toomey, D., Walsh, K.,, Sweeney, C., Leavy, O., Fletcher, J., Lavelle, E., Dunne, P. and Mills, K.H.G., Attenuating regulatory T cell induction by TLR agonists through inhibition of p38 MAPK signaling in dendritic cells enhances their efficacy as vaccine adjuvants and cancer immunotherapeutics, Journal of Immunology, 180, (6), 2008, p3797 - 3806
Journal Article; Published; Peer Reviewed; Author Profiles: LAVELLEE MILLSK FLETCHJ ; URL

Hurst, T & Bowie, A.G, Innate immune signalling pathways: lessons from vaccinia virus, Future Virology, 3, (2), 2008, p147 - 156
Journal Article; Published; Peer Reviewed; Author Profile: AGBOWIE; DOI; URL

Unterholzner, L. & Bowie, A.G. , The interplay between viruses and innate immune signalling: recent insights and therapeutic opportunities, Biochemical Pharmacology, 75, (3), 2008, p589 - 602
Journal Article; Published; Peer Reviewed; Author Profile: AGBOWIE; DOI; URL

Fennelly, N.F., Sisti, F, Higgins, S.C., Ross, P., van der Heide, H. Mooi, F.R., Boyd, A.P. and Mills, K.H.G., Bordetella pertussis expresses a functional type III secretion system that subverts protective innate and adaptive immune responses., Infection and Immunity, 76, (3), 2008, p1257 - 1266
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI

Conroy, H. Marshall, N.A. and Mills, K.H.G., TLR ligand suppression or enhancement of Treg cell - A double edged sword in immunity to tumors. , Oncogene, 27, (2), 2008, p168 - 180
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI; URL

Greene, LM, Campiani, GC, Lawler, M, Williams, DC and Zisterer, DM, BubR1 is Required for a Sustained Mitotic Spindle checkpoint arrest in Human Cancer cells treated with a tubulin-targetting pyrrolo-1,5-benzoxazepine, Molecular Pharmacology, 73, (2), 2008, p419 - 430
Journal Article; Published; Peer Reviewed; Author Profiles: DZISTRER DWILLIMS MPLAWLER ; DOI; URL