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Publications

Below is the list of peer and non peer publications from the School of Biochemistry and Immunology.

Show: AllPeer ReviewedNon Peer Reviewed
96 publications from 2005

Stevenson, Nigel, Mechanisms of SOCS3 Phosphorylation upon Interleukin-6 Stimulation, The Journal of Biological Chemistry, 280, (36), 2005, p31478 - 31488
Journal Article; Published; Peer Reviewed; Author Profile: STEVENNJ; DOI

Eamon P. Breen, Detection, Expression and Elucidation of the Mechanism of Action of Mitochondrial Uncoupling protein 1, Trinity College Dublin, 2005
Thesis; Published; Peer Reviewed; Author Profile: RKPORTER

Clare M. Brennan, Investigations into the Physiological Expression of UCP1 and UCP3, Trinity College Dublin, 2005
Thesis; Published; Peer Reviewed; Author Profile: RKPORTER

Richard K. Porter, "Mitochondrial Coupling" , Mitochondria in Physiology Conference, , Schröcken, Austria, July, 2005, Erich Gnaiger
Invited Talk; Published; Peer Reviewed; Author Profile: RKPORTER; URL

Pérez-Morga, D., Vanhollebeke, B., Paturiaux-Hanocq, F., Nolan, D.P., Lins, L., Homblé, F., Vanhamme, L., Tebabi, P., Pays, A., Poelvoorde, P., Jacquet, A., Brasseur, R., Pays, E., Microbiology: Apolipoprotein L-I promotes trypanosome lysis by forming pores in lysosomal membranes, Science, 309, (5733), 2005, p469-472
Journal Article; Published; Peer Reviewed; Author Profile: DENOLAN

Rubotham, J., Woods, K., Garcia-Salcedo, J.A., Pays, E., Nolan, D.P., Characterization of two protein disulfide isomerases from the endocytic pathway of bloodstream forms of Trypanosoma brucei, Journal of Biological Chemistry, 280, (11), 2005, p10410-10418
Journal Article; Published; Peer Reviewed; Author Profile: DENOLAN

Razorenova OV, Agapova LS, Budanov AV, Ivanov AV, Strunina SM, Chumakov PM, [Retroviral reporter systems for the assessment of activity of stress-induced signal transduction pathways controlled by p53, HIF-1 and HSF-1 transcription factors]., Gene, 350, (1), 2005, p89 - 98
Journal Article; Published; Peer Reviewed; Author Profile: BUDANOVA; DOI

Razorenova OV, Agapova LS, Budanov AV, Ivanov AV, Strunina SM, Chumakov PM, Retroviral reporter systems for the assessment of activity of stress-induced signal transduction pathways controlled by p53, HIF-1 and HSF-1 transcription factors., Molecular Biology, 39, (2), 2005, p286 - 293
Journal Article; Published; Peer Reviewed; Author Profile: BUDANOVA; URL

Sablina AA, Budanov AV, Ilyinskaya GV, Agapova LS, Kravchenko JE, Chumakov PM, The antioxidant function of the p53 tumor suppressor., Nature Medicine, 11, (12), 2005, p1306 - 1313
Journal Article; Published; Peer Reviewed; Author Profile: BUDANOVA; DOI

Stevenson NJ, Haan S, McClurg A, Armstrong MA, Heinrich P, Johnston JA. , The chemoattractants IL-8 and fMLP regulate G-CSF signalling by inducing suppressor of cytokine signalling (SOCS)-1 expression., Immunology, 116, (1), 2005, pp73
Conference Paper; Published; Non Peer Reviewed; Author Profile: STEVENNJ

Sommer, U., Schmid, C., Sobota, R.M., Lehmann, U., Stevenson, N.J., Johnston, J.A., Schaper, F., Heinrich, P.C., Haan, S., Mechanisms of SOCS3 phosphorylation upon interleukin-6 stimulation: Contributions of Src- and receptor-tyrosine kinases, Journal of Biological Chemistry, 280, (36), 2005, p31478-31488
Journal Article; Published; Peer Reviewed; Author Profile: STEVENNJ; DOI

McLoughlin RM, Resolving peritoneal inflammation :Flicking the right "switches". , Peritoneal Dialysis International, 25, 2005, p223 - 229
Journal Article; Published; Peer Reviewed; Author Profile: MCLOUGRM

McLoughlin RM, Jenkins BJ, Grail D, Williams AS, Fielding CA, Parker CR, Ernst M, Topley N, Jones SA, IL-6 trans-signaling via STAT3 directs T cell infiltration in acute inflammation., Proceedings of the National Academy of Sciences of the United States of America, 102, (27), 2005, p9589-94
Journal Article; Published; Peer Reviewed; Author Profile: MCLOUGRM

Jenkins BJ, Grail D, Nheu T, Najdovska M, Wang B, Waring P, Inglese M, McLoughlin RM, Jones SA, Topley N, Baumann H, Judd LM, Giraud AS, Boussioutas A, Zhu HJ, Ernst M, Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-beta signaling., Nature medicine, 11, (8), 2005, p845-52
Journal Article; Published; Peer Reviewed; Author Profile: MCLOUGRM

Fielding CA, McLoughlin RM, Colmont CS, Kovaleva M, Harris DA, Rose-John S, Topley N, Jones SA, Viral IL-6 blocks neutrophil infiltration during acute inflammation., Journal of immunology (Baltimore, Md. : 1950), 175, (6), 2005, p4024-9
Journal Article; Published; Peer Reviewed; Author Profile: MCLOUGRM

Ni J, Cnops Y, McLoughlin RM, Topley N, Devuyst O, Inhibition of nitric oxide synthase reverses permeability changes in a mouse model of acute peritonitis., Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis, 25 Suppl 3, 2005, pS11-4
Journal Article; Published; Peer Reviewed; Author Profile: MCLOUGRM

Lipina C., Huang X., Finlay D., McManus EJ., Alessi DR., Sutherland C, Analysis of hepatic gene transcription in mice expressing insulin-insensitive GSK3, Biochemical Journal, 392, (3), 2005, p633 - 639
Journal Article; Published; Peer Reviewed; Author Profile: FINLAYD; DOI; URL

Caffrey, M., The Membrane Protein Data Bank. - An on-line, searchable, relational database with select structural and functional information on membrane proteins and peptides. , 2005, -
Miscellaneous; Published; Peer Reviewed; Author Profile: MCAFFRE; URL

Clogston, J., Graciun, G., Hart, D. J., Caffrey, M., Controlling Release from the Lipidic Cubic Phase by Selective Alkylation., Journal of Controlled Release, 102, (2), 2005, p441-461
Journal Article; Published; Peer Reviewed; Author Profile: MCAFFRE; DOI

Liu, W., Caffrey, M, Gramicidin Structure and Disposition in Highly Curved Membranes. , Journal Structural Biology, 150, (1), 2005, p23-40
Journal Article; Published; Peer Reviewed; Author Profile: MCAFFRE; DOI

Cherezov, M., Caffrey, M., A simple and inexpensive nanoliter volume dispenser for highly viscous materials used in membrane protein crystallization., Journal of Applied Crystallography, 38, 2005, p398-400
Journal Article; Published; Peer Reviewed; Author Profile: MCAFFRE; DOI

Nolan, D.P., Jackson, D.G., Biggs, M.J., Brabazon, E.D., Pays, A., Van Laethem, F., Paturiaux-Hanocq, F., (...), Pays, E., Erratum: Characterization of a novel alanine-rich protein located in surface microdomains in Trypanosoma, brucei (Journal of Biological Chemistry (2000) 275 (4072-4080)) , 2005, - 31340
Miscellaneous; Published; Peer Reviewed; Author Profile: DENOLAN

Modified bacterial toxins in, editor(s)Charles J Hackett & Donald A Harn Jr, , Vaccine Adjuvants: Immunological and Clinical Principles., Publisher Humana, 2005, pp296 , [Lavelle EC., Leavy O. Mills KHG. ]
Book Chapter; Published; Peer Reviewed; Author Profiles: MILLSK LAVELLEE

Fletcher JM, Vukmanovic-Stejic M, Dunne PJ, Birch KE, Cook JE, Jackson SE, Salmon M, Rustin MH, Akbar AN., Cytomegalovirus-specific CD4+ T cells in healthy carriers are continuously driven to replicative exhaustion., Journal of Immunology , 175, (12), 2005, p8218-8225
Journal Article; Published; Peer Reviewed; Author Profile: FLETCHJ; URL

Akbar AN, Fletcher JM., Memory T cell homeostasis and senescence during aging., Current Opinion in Immunology, 17, (5), 2005, p480-485
Review Article; Published; Peer Reviewed; Author Profile: FLETCHJ; DOI

Plunkett FJ, Franzese O, Belaramani LL, Fletcher JM, Gilmour KC, Sharifi R, Khan N, Hislop AD, Cara A, Salmon M, Gaspar HB, Rustin MH, Webster D, Akbar AN. , The impact of telomere erosion on memory CD8+ T cells in patients with X-linked lymphoproliferative syndrome., Mechanisms of Ageing and Development, 126, (8), 2005, p855-865
Journal Article; Published; Peer Reviewed; Author Profile: FLETCHJ; DOI

Dunne PJ, Belaramani L, Fletcher JM, Fernandez de Mattos S, Lawrenz M, Soares MV, Rustin MH, Lam EW, Salmon M, Akbar AN, Quiescence and functional reprogramming of Epstein-Barr virus (EBV)-specific CD8+ T cells during persistent infection. , Blood, 106, (2), 2005, p558-565
Journal Article; Published; Peer Reviewed; Author Profile: FLETCHJ; DOI

Higgs, R, Lynn, DJ, Gaines, S, McMahon, J, Tierney, J, James, T, Lloyd, AT, Mulcahy, G, O'Farrelly, C, The synthetic form of a novel chicken beta-defensin identified in silico is predominantly active against intestinal pathogens., Immunogenetics, 57, (1-2), 2005, p90-8
Journal Article; Published; Peer Reviewed; Author Profile: OFARRECL; DOI; URL

Dean, J, McCarthy, D, Golden-Mason, L, O'Farrelly, C, Trephine biopsies are enriched for activated T/NK cells and cytotoxic T cells., Immunology letters, 99, (1), 2005, p94-102
Journal Article; Published; Peer Reviewed; Author Profile: OFARRECL; DOI; URL

Dean, J, McCarthy, D, Lawler, M, Doherty, DG, O'Farrelly, C, Golden-Mason, L, Characterization of NKR+ T-cell subsets in human bone marrow: implications for immunosurveillance of neoplasia., Clinical immunology (Orlando, Fla.), 114, (1), 2005, p42-51
Journal Article; Published; Peer Reviewed; Author Profiles: DOHERTDE OFARRECL ; DOI; URL

Doyle S, Jefferies CA and O'Neill LA, Bruton's tyrosine kinase is involved in p65-mediated transactivation and phosphorylation of p65 on serine 536 during NF-kappa B activation by LPS, Journal of Biological Chemistry, 280, (25), 2005, p23496 - 23501
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI

Mok KH (Inventor), Mok KH (Assignee), Improvements to retro-inverso isomers, 2005, Registered UK Patent No. 2389043 (27 July 2005)
Patent; Published; Peer Reviewed; Author Profile: MOK1

Goez, M, Mok KH, Hore PJ, Photo-CIDNP Experiments with an Optimized Presaturation Pulse Train, Gated Continuous Illumination, and a Background-Nulling Pulse Grid, Journal of Magnetic Resonance, 177, (2), 2005, p236 - 246
Journal Article; Published; Peer Reviewed; Author Profile: MOK1; DOI

Cunningham, C., Deacon, R.M.J., Chan, K., Boche, D., Rawlins, J.N.P. and Perry, V.H. , Neuropathologically distinct prion disease strains give rise to similar behavioural profiles, Neurobiology of Disease, 18, 2005, p258-269
Journal Article; Published; Peer Reviewed; Author Profile: CUNNINCO; DOI

Cunningham C., Wilcockson, D.C., Boche, D. and Perry, V.H., A comparison of brain and peripheral organ cytokine and acute phase protein transcription in the ME7 model of prion disease, Journal of Virology, 79, (8), 2005, p5174-5184
Journal Article; Published; Peer Reviewed; Author Profile: CUNNINCO

Felton, L., Cunningham, C. Rankine, E., Waters, S. and V. Hugh Perry, The role of monocyte chemoattractant protein-1 (MCP-1) in murine prion disease: separation of early behavioural dysfunction from overt clinical disease, Neurobiology of Disease, 20, (2), 2005, p283-295
Journal Article; Published; Peer Reviewed; Author Profile: CUNNINCO; DOI

Cunningham, C., Wilcockson D.C., Campion, S., Lunnon K. and Perry, V.H. , Central and systemic endotoxin challenges exacerbate the local inflammatory response and increase neuronal death during chronic neurodegeneration, Journal of Neuroscience, 25, ((40)), 2005, p9275-9284
Journal Article; Published; Peer Reviewed; Author Profile: CUNNINCO; DOI

Mouse behavioural studies and what they can teach us about prion diseases in, editor(s)David Brown , Neurodegeneration and prion disease, New York, Springer, 2005, pp111 - 137, [Colm Cunningham]
Book Chapter; Published; Peer Reviewed; Author Profile: CUNNINCO; DOI

Mok KH, Nagashima T, Day IJ, Hore PJ, Dobson CM, Multiple subsets of side-chain packing in partially folded states of alpha-lactalbumins, Proceedings of the National Academy of Sciences of the USA, 102, (25), 2005, p8899 - 8904
Journal Article; Published; Peer Reviewed; Author Profile: MOK1; DOI; URL

Huo ZM, Sinha R, McNeela EA, Borrow R, Giemza R, Cosgrove C, Heath PT, Mills KHG, Rappuoli R, Griffin GE, Lewis DJM, Induction of protective serum meningococcal bactericidal and diphtheria-neutralizing antibodies and mucosal immunoglobulin a in volunteers by nasal insufflations of the Neisseria meningitidis serogroup C polysaccharide-CRM197 conjugate vaccine mixed with chitosan, Infection and Immunity, 73, (12), 2005, p6256 - 6265
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI

Kelly VP, Takafumi S, Nakajima O, Arai T, Tamai Y, Takahashi S, Nishimura S, Yamamoto M., The distal sequence element of the selenocysteine tRNA gene is a tissue dependant enhancer essential for mouse embryogenesis, Mol. Cell Biol., 25, 2005, p3658 - 3669
Journal Article; Published; Peer Reviewed; Author Profile: KELLYVP; DOI

Kobayashi T, Sakamoto K, Takimura T, Sekine R, Kelly VP, Kamata K, Nishimura S, Yokoyama S., Structural basis of nonnatural amino acid recognition by an engineered aminoacyl-tRNA synthetase for genetic code expansion, Proceedings of the National Academy of Sciences of the United States of America, 102, (5), 2005, p1366 - 1371
Journal Article; Published; Peer Reviewed; Author Profile: KELLYVP; DOI

Kobayashi T, Takimura T, Sekine R, Kelly VP, Kamata K, Sakamoto K, Nishimura S, Yokoyama S., Structural snapshots of the KMSKS loop rearrangement for amino acid activation by bacterial tyrosyl-tRNA synthetase, J. Mol. Biol., 346, (1), 2005, p105 - 117
Journal Article; Published; Peer Reviewed; Author Profile: KELLYVP; DOI

Loscher CE, Draper E, Leavy O, Kelleher D, Mills KHG & Roche HM , Conjugated linoleic acid suppresses NF-kappa B activation and IL-12 production in dendritic cells through ERK-mediated IL-10 induction, Journal of Immunology, 175, (8), 2005, p4990 - 4998
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; URL

Arias-Salgado EG, Haj F, Dubois C, Moran B, Kasirer-Friede A, Furie BC, Furie B, Neel BG, and Shattil SJ, PTP-1B is an essential positive regulator of platelet integrin signaling , Journal of Cell Biology, 170, (5), 2005, p837 - 845
Journal Article; Published; Peer Reviewed; Author Profile: MORANBA

Hart OM, Athie-Morales V, O'Connor GM and Gardiner CM, TLR7/8 mediated activation of human NK cells results in accessory cell dependent IFN-gamma production, Journal of Immunology, 175, 2005, p1636 - 1642
Journal Article; Published; Peer Reviewed; Author Profile: GARDINEC

Dunne A and O'Neill L, New insights into the post-translational modification of Toll-like receptor, Journal of Endotoxin Research, 11, (6), 2005, p325 - 332
Journal Article; Published; Peer Reviewed; Author Profiles: AIDUNNE LAONEILL ; DOI; URL

O'Toole D, Abde;-Latif AM, Long A, Windle HJ, Murphy AM, Bowie A, O'Neill LA, Weir DG, Kelleher D, Low pH and Helicobacter pylori increase nuclear factor kappa B binding in gastric epithelial cells: a common pathway for epithelial cell injury?, Journal of Cellular Biochemistry, 96, (3), 2005, p589 - 588
Journal Article; Published; Peer Reviewed; Author Profiles: AGBOWIE LAONEILL ; DOI; URL

Djeha HA, Todryk SM, Pelech S, Wrighton CJ, Irvine AS, Mountain A, Mills, K.H.G., Lipinski KS , Anti-tumour immune response mediated by Adenoviral GDEPT using nitroreductase/CB1954 is enhanced by high-level co-expression of heat shock protein 70., Cancer Gene Therapy, 12, (6), 2005, p560-571
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI; URL

Noone, C.M. Lewis, EA, Frawely, A.B., Newman, R.W., Mahon, B.P., Mills, K.H.G. and Johnson, P.A. , Novel mechanism of immunosuppression by influenza virus haemagglutinin: selective suppression of IL-12p35 transcription in murine bone marrow-derived dendritic cells., Journal of General Virology, 86, (7), 2005, p1885-1890
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI

McGuirk, P., Higgins, SC, Mills, K.H.G. , Regulatory cells and the control of respiratory infection. , Current Allergy and Asthma Reports, 5, (1), 2005, p51 - 55
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; URL

Rubotham, J., Woods, K., Garcia-Salcedo, J.A., Pays, E. and Nolan, D.P., Characterization of two protein disulphide iosmerases from the endocytic pathway of Trypanosoma brucei, Journal of Biological Chemistry, 280, 2005, p10410 - 10418
Journal Article; Published; Peer Reviewed; Author Profile: DENOLAN; DOI

Perez-Morga D., Vanhollebeke B., Paturiaux-Hanocq F., Nolan D.P., Lins L., Homble F., Vanhamme L., Tebabi P., Pays A., Poelvoorde P., Jacquet A., Brasseur R., Pays E., Apolipoprotein L-I promotes trypanosome lysis by forming pores in lysosomal membranes, Science, 309, 2005, p469 - 472
Journal Article; Published; Peer Reviewed; Author Profile: DENOLAN; DOI

Greene, L.M., Fleeton, M., Mulligan, J., Chikana, G., Sheahan, B.J., Atkins, G.J., Campiani, G., Nacci, V., Lawler, M., Williams, D.C. and Zisterer, D.M., The pyrrolo-1,5-benzoxazepine, PBOX-6, inhibits the growth of breast cancer cells in vitro independent of estrogen receptor status, and inhibits breast tumour growth in vivo, Oncology Reports, 14, 2005, p1357 - 1363
Journal Article; Published; Peer Reviewed; Author Profiles: DZISTRER DWILLIMS MPLAWLER GATKINS

Mills, K.H.G., Mahon, B., Griffin, F., Ryan, M, Genetic Institute / Wyeth, IL-12 as an adjuvant for Bordetella pertussis vaccines., 2005, US patent application 11/071,352. Pub No US2005/0158276 A1; US6929794 - 2005-08-16; US2005158276 - 2005-07-21; JP2005112865 - 2005-04-28.
Patent; Published; Peer Reviewed; Author Profile: MILLSK

B Mee, D Kelleher, J Frias, R Malone, KF Tipton, GT Henehan, HJ Windle, Characterization of cinnamyl alcohol dehydrogenase of Helicobacter pylori. An aldehyde dismutating enzyme, FEBS J, 272, (5), 2005, p1255 - 1264
Journal Article; Published; Peer Reviewed; Author Profiles: KTIPTON HJWINDLE ; DOI

Luke O'Neill and Elisabeth Brint (editors), Toll-like receptors in inflammation, Plenum Press, 2005
Book; Published; Peer Reviewed; Author Profile: LAONEILL

O'Neill LA, TLRs play good cop bad cop in lung, Nature Medicine, 11, (11), 2005, p1161 - 1162
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Brady G, Boggan L, Bowie A and O'Neill LA, Schlafen-1 causes a cell cycle arrest by inhibiting induction of cyclin D1, Journal of Biological Chemistry, 280, (35), 2005, p30723 - 30734
Journal Article; Published; Peer Reviewed; Author Profiles: BRADYG1 LAONEILL ; DOI

Gouin, S.G., Breen, E.P., Pilgrim, W., Murphy, P.V. & Porter R.K., Elucidation of the mechanism of mitochondrial uncoupling protein using a synthetic glycolipid, Bioscience 2005, Glasgow, Scotland. UK, 2005
Meeting Abstract; Published; Peer Reviewed; Author Profile: RKPORTER; URL

Gouin, S.G., Breen, E.P., Pilgrim, W., Murphy, P.V., Porter R.K., Elucidation of the mechanism of mitochondrial uncoupling protein function using a synthetic glycolipid, Mitochondria in Physiology, MiP2005, 2005
Journal Article; Published; Peer Reviewed; Author Profile: RKPORTER; URL

Lelivelt CL, McCabe MS, Newell CA, Desnoo CB, van Dun KM, Birch-Machin I, Gray JC, Mills KH, Nugent JM., Stable Plastid Transformation in Lettuce (Lactuca sativa L.), Plant Molecular Biology, 58, 2005, p763-774
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI; URL

Loscher, CL Leavy, O. Kelleher, D, *Mills, K.H.G and *Roche, H.M. *Equal contribution, Conjugated linoleic acid suppresses NFkB activation and IL-12 production in dendritic cells through ERK-mediated IL-10 induction., Journal of Immunology, 175, (8), 2005, p4990 - 4998
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; URL

Boyd, A.P., Ross, P.J., Conroy, H., Mahon, N Lavelle, E.C.and Mills, K.H.G., Bordetella pertussis adenylate cyclase toxin modulates innate and adaptive immune responses: distinct roles for acylation and enzymatic activity in immunomodulation and cell death, Journal of Immunology, 175, 2005, p730 - 738
Journal Article; Published; Peer Reviewed; Author Profiles: LAVELLEE MILLSK ; URL

Enzyme Classification and Nomenclature , Encyclopedia of the Life Sciences, Chichester, John Wiley & Sons, Ltd,, 2005, pp14 pp , [Tipton, K. F. and Boyce, S.]
Item in dictionary or encyclopaedia, etc; Published; Peer Reviewed; Author Profile: KTIPTON; DOI; URL

J.A. Kelly, G.A. Scalabrino, G.R. Slator, A.A. Cullen, J.F. Gilmer, D.G. Lloyd, G.W. Bennett, K. Bauer, K.F. Tipton and C.H. Williams., Structure-activity studies with high affinity inhibitors of pyroglutamyl-peptidase II., Biochemical Journal, 389, 2005, p569 - 576
Journal Article; Published; Peer Reviewed; Author Profile: KTIPTON

Amine Oxidases and Drug Metabolism. in, editor(s)F. Oesch , Proc 15th Int Symp Microsomes and Drug Oxidations, Mainz Germany. , Bologna, Italy , Merimond S.r.l., 2005, pp47 - 54, [K.F. Tipton and M. Strolin Benedetti]
Book Chapter; Published; Peer Reviewed; Author Profile: KTIPTON

Lavelle, E.C, Generation of improved mucosal vaccines by induction of innate immunity., Cellular And Molecular Life Sciences, 62, (23), 2005, p2750-2770
Journal Article; Published; Peer Reviewed; Author Profile: LAVELLEE; DOI

Nolan Y, Maher FO, Clarke RM, Brady MT, Bolton AE, Mills KHG, Lynch MA, Role of interleukin-4 in regulation of age-related inflammatory changes in the hippocampus., Journal of Biological Chemistry, 280, (10), 2005, p9354 - 9362
Journal Article; Published; Peer Reviewed; Author Profiles: MILLSK LYNCHMA ; DOI

Armstrong ME, Lavelle EC, Loscher CE, Lynch MA, Mills KHG, Proinflammatory Responses in the Murine Brain after Intranasal Delivery of Cholera Toxin: Implications for the Use of AB Toxins as Adjuvants in Intranasal Vaccines, Journal of Infectious Diseases, 192, (9), 2005, p1628 - 1633
Journal Article; Published; Peer Reviewed; Author Profiles: LYNCHMA ARMSTRP MILLSK LAVELLEE ; DOI; URL

Melchjorsen, J, Jensen, S.B., Malmgaard,L., Rasmussen, S.B., Weber, F., Bowie, A.G., Matikainen, S. & Paludan, S.R. , Activation of Innate Defense against a Paramyxovirus Is Mediated by RIG-I and TLR7 and TLR8 in a Cell-Type-Specific Manner, The Journal of Virology, 79, (20), 2005, p12944 - 12951
Journal Article; Published; Peer Reviewed; Author Profile: AGBOWIE; DOI; URL

Carroll, T.P., Greene, C.M., Taggart, C.C., Bowie, A.G., O'Neill, S.J. & McElvaney, N.G., Viral inhibition of IL-1 and neutrophil elastase-induced inflammatory responses in bronchial epithelial cells, The Journal of Immunology, 175, (11), 2005, p7594 - 7601
Journal Article; Published; Peer Reviewed; Author Profile: AGBOWIE; URL

Haga, I.H. and Bowie, A.G., Evasion of Innate Immunity by Vaccinia Virus, Parasitology, 130, 2005, pS11 - S25
Journal Article; Published; Peer Reviewed; Author Profile: AGBOWIE; DOI; URL

Toll-like receptors as key sensors of viral infection in, editor(s)L.A.J. O'Neill and E. Brint , Toll-like Receptors in Inflammation, 2005, pp143 - 171, [Keating, S.E. and Bowie, A.G.]
Book Chapter; Published; Peer Reviewed; Author Profile: AGBOWIE

Lloyd DG, Smith HM, O'Sullivan T, Zisterer DM, Meegan MJ, Synthesis, Structure-Activity Relationships and Antagonistic Effects in Human MCF-7 Breast Cancer Cells of Flexible Estrogen Receptor Modulators, Medicinal Chemistry, 1, (4), 2005, p335 - 353
Journal Article; Published; Peer Reviewed; Author Profiles: DZISTRER MMEEGAN ; DOI; URL

Maloney, G, Schroeder, M & Bowie, AG, Vaccinia virus protein A52R activates p38 mitogen-activated protein kinase and potentiates lipopolysaccharide-induced interleukin-10, The Journal of Biological Chemistry, 280, (280), 2005, p30838 - 30844
Journal Article; Published; Peer Reviewed; Author Profile: AGBOWIE; DOI

Schroeder, M & Bowie AG, TLR3 in antiviral immunity: key player or bystander?, Trends in Immunology, 26, (9), 2005, p462 - 468
Journal Article; Published; Peer Reviewed; Author Profile: AGBOWIE; DOI; URL

Brady, G, Boggan, L, Bowie, AG & O'Neill, LAJ, Schlafen-1 causes cell cycle arrest by inhibiting induction of cyclin D1, The Journal of Biological Chemistry, 280, 2005, p30723 - 30734
Journal Article; Published; Peer Reviewed; Author Profile: AGBOWIE; URL

Carroll, A.M., Haines, L.R., Pearson, T.W., Fallon, P.G., Walsh, C.M., Brennan, C., Breen, E. & Porter, R.K., Identification of a functioning mitochondrial uncoupling protein 1 in thymus, Journal of Biological Chemistry, 280, 2005, p155534 - 155543
Journal Article; Published; Peer Reviewed; Author Profiles: PFALLON RKPORTER ; DOI

Panayi, G and O'Neill LA, Targetting innate and adaptive immunity in arthritis, New England Jounral of Medicine, 2005
Journal Article; In_press; Peer Reviewed; Author Profile: LAONEILL

Dunne A and O'Neill LA, Adaptor usage and Toll-like receptor signaling specificity, FEBS Lett., 579, (15), 2005
Review; Published; Peer Reviewed; Author Profiles: AIDUNNE LAONEILL ; DOI; URL

Doyle S, Jefferies CA and O'Neill LA, Bruton's tyrosine kinase is involved in p65-mediated transactivation and phosphorylation of p65 on serine 536 during NF-kappa B activation by LPS, J Biol Chem., 280, (25), 2005, p23496 - 23501
Journal Article; Published; Peer Reviewed; Author Profiles: DOYLES8 LAONEILL ; DOI; URL

Liew, E, Xu, D, Brint, E, O'Neill, LA, Negative regulation of TLR signalling, Nature Rev. Immunol., 5, (6), 2005, p446 - 458
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

O'NEILL LA et al, PCT application: 'TLR14 - a novel Toll-like receptor', 2005
Patent; Published; Peer Reviewed; Author Profile: LAONEILL

O'NEILL LA et al, PCT application - 'Assays relating to Toll-like receptor-4 and compositions for modulating same', 2005
Patent; Published; Peer Reviewed; Author Profile: LAONEILL

Carroll, A.M., Haines, L.R., Pearson, T.W., Fallon, P., Walsh, C., Brennan, C., Breen, E.P. & Porter, R.K., Detection of a functioning UCP 1in Thymus, Journal of Biological Chemistry, 280, 2005, p15534 - 15543
Journal Article; Published; Peer Reviewed; Author Profile: RKPORTER; URL

Gouin, S.G, Pilgrim, W., Porter, R.K. and Murphy, P.V., Synthesis of a glycolipid for studying mechanisms of mitochondrial uncoupling proteins, Carbohydrate Research, 340, 2005, p1547 - 1552
Journal Article; Published; Peer Reviewed; Author Profile: RKPORTER; URL

McGee, MM, Gemma, S, Rammunno, A, Zisterer,DM, Fatterusso, C, Catalanotti, B, Butini, S, Fiorini,I, Pisano, C, Cucco, C, Novellino, E, Nacci, V, Williams, DC and Campiani, G, Pyrolo [1,5] benzoxathiazepines as a new class of potent apoptotic agents. Biological studies and identification of an intracellular location of their drug target., Journal of Medicinal Chemistry, 48, (13), 2005, p4367 - 4377
Journal Article; Published; Peer Reviewed; Author Profiles: DZISTRER DWILLIMS ; DOI; URL

Bowie, A.G. & Haga, I.R. , The role of Toll like receptors in the host response to viruses. , Molecular Immunology, 42, 2005, p859 - 867
Journal Article; Published; Peer Reviewed; Author Profile: AGBOWIE; URL

Stack, J. Haga, I.R., Schroeder, M., Bartlett, N.W., Maloney, G., Reading, P.C., Fitzgerald, K.A., Smith, G.L. & Bowie, A.G, Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence, The Journal of Experimental Medicine, 201, (6), 2005, p1007 - 1018
Journal Article; Published; Peer Reviewed; Author Profile: AGBOWIE; DOI; URL

Mee, B., Kelleher, D., Frias, J., Malone, R., Tipton, K.F., Henehan ,G.T. and Windle,H.J., Characterization of cinnamyl alcohol dehydrogenase of Helicobacter pylori., FEBS JOURNAL, 272, (5), 2005, p1255 - 1264
Journal Article; Published; Peer Reviewed; Author Profile: KTIPTON

Apweiler, R., Cornish-Bowden, A., Hofmeyr, J.H., Kettner, C., Leyh, T.S., Schomburg, D. and Tipton, K.F. , The importance of uniformity in reporting protein-function data. , Trends in Biochemical Sciences, 30, 2005, p11 - 12
Journal Article; Published; Peer Reviewed; Author Profile: KTIPTON

Daly, L.M., Johnson, P.A., Nicolson, C., Robertson, J. and Mills, K.H.G., Innate IL-10 promotes the induction of Th2 responses with plasmid DNA expressing HIV gp120, Vaccine, 23, 2005, p963 - 974
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI; URL

Modified Bacterial toxins in, editor(s)D. Harn and C.J Hackett , Vaccine Adjuvants: Immunological and Clinical Principles, Humana Press, 2005, pp113 - 155, [Lavelle, E., Leavy, O., Mills, K.H.G.]
Book Chapter; Published; Peer Reviewed; Author Profile: MILLSK

Evasion of immune responses by bacteria. in, editor(s)S. Kaufmann and M. Steward , Topley and Wilson's Microbiology and Microbial Infections: Immunology Volume, London, Hodder Arnold Publishers Ltd, 2005, pp645 - 674, [Mills, K.H.G. and Boyd, A]
Book Chapter; Published; Peer Reviewed; Author Profile: MILLSK

O'Neill LA , Immunity's early warning system, Scientific American , 292, (1), 2005, p38 - 45
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; URL