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Publications

Below is the list of peer and non peer publications from the School of Biochemistry and Immunology.

Show: AllPeer ReviewedNon Peer Reviewed
86 publications from 2004

Carroll, A.M. and Porter, R.K., Starvation-sensitive UCP 3 protein expression in thymus and spleen mitochondria, Biochimica et Biophysica Acta - Proteins and Proteomics, 1700, (2), 2004, p145-150
Journal Article; Published; Peer Reviewed; Author Profile: RKPORTER; DOI; URL

Stevenson NJ, Haan S, McClurg AE, McGrattan MJ, Armstrong MA, Heinrich PC, JA Johnston, The Chemoattractants, IL-8 and Formyl-Methionyl-Leucyl-Phenylalanine, Regulate Granulocyte Colony-Stimulating Factor Signaling by Inducing Suppressor of Cytokine, Journal of Immunology, 173, (5), 2004, pp3243 - 3249
Conference Paper; Published; Non Peer Reviewed; Author Profile: STEVENNJ

Audrey M. Carroll, An Investigation into the Expression and Physiological Function of Mitochondrial Uncoupling Proteins, Trinity College Dublin, 2004
Thesis; Published; Peer Reviewed; Author Profile: RKPORTER

Richard K. Porter, "Detection of a functioning UCP 1 in Thymus" , Bioscience 2004 Conference, , Glasgow, Scotland., 2004, The UK Biochemical Society
Invited Talk; Published; Peer Reviewed; Author Profile: RKPORTER

García-Salcedo, J.A., Pérez-Morga, D., Gijón, P., Dilbeck, V., Pays, E., Nolan, D.P., A differential role for actin during the life cycle of Trypanosoma brucei, EMBO Journal, 23, (4), 2004, p780-789
Journal Article; Published; Peer Reviewed; Author Profile: DENOLAN

Budanov AV, Sablina AA, Feinstein E, Koonin EV, Chumakov PM, Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD., Science, 304, (5670), 2004, p596 - 600
Journal Article; Published; Peer Reviewed; Author Profile: BUDANOVA; DOI

Stevenson, N.J., Haan, S., McClurg, A.E., McGrattan, M.J., Armstrong, M.A., Heinrich, P.C., Johnston, J.A., The chemoattractants, IL-8 and formyl-methionyl-leucyl-phenylalanine, regulate granulocyte colony-stimulating factor signaling by inducing suppressor of cytokine signaling-1 expression, Journal of Immunology, 173, (5), 2004, p3243-3249
Journal Article; Published; Peer Reviewed; Author Profile: STEVENNJ

McLoughlin RM, Hurst SM, Nowell MA, Harris DA, Horiuchi S, Morgan LW, Wilkinson TS, Yamamoto N, Topley N, Jones SA, Differential regulation of neutrophil-activating chemokines by IL-6 and its soluble receptor isoforms., Journal of immunology (Baltimore, Md. : 1950), 172, (9), 2004, p5676-83
Journal Article; Published; Peer Reviewed; Author Profile: MCLOUGRM

Finlay D., Patel S., Dickson L.M., Shapiro N., Marquez R., Rhodes C.J., Sutherland C., Glycogen synthase kinase-3 regulates IGFBP-1 gene transcription through the thymine-rich insulin response element, BMC Molecular Biology, 5, (15), 2004
Journal Article; Published; Peer Reviewed; Author Profile: FINLAYD; DOI; URL

*Cherezov, V., Peddi, A., Muthusubramaniam, L., Zheng, Y.F. M. Caffrey., A Robotic System For Crystallizing Membrane And Soluble Proteins In Lipidic Mesophases., Acta Crystallographica Section D, 60, (10), 2004, p1795-1807
Journal Article; Published; Peer Reviewed; Author Profile: MCAFFRE; DOI

Misquitta, Y., Cherezov, V., Havas, F., Patterson, S., Mohan, J., Wells, A., Hart, D., Caffrey, M., Rational Design of Lipid for Membrane Protein Crystallization. , Journal of Structural Biology, 148, (2), 2004, p169-175
Journal Article; Published; Peer Reviewed; Author Profile: MCAFFRE; DOI

Misquitta, L.V., Misquitta, Y., Cherezov, V., Slattery, O., Mohan, J. M., Hart, D., Zhalnina, M., Cramer, W. A., Caffrey, M., Membrane protein crystallization in lipidic mesophases with tailored bilayers. , Structure, 12, (12), 2004, p2113-2124
Journal Article; Published; Peer Reviewed; Author Profile: MCAFFRE; DOI

Reed JR, Vukmanovic-Stejic M, Fletcher JM, Soares MV, Cook JE, Orteu CH, Jackson SE, Birch KE, Foster GR, Salmon M, Beverley PC, Rustin MH, Akbar AN. , Telomere erosion in memory T cells induced by telomerase inhibition at the site of antigenic challenge in vivo., Journal of Experimental Medicine, 199, (10), 2004, p1433-1443
Journal Article; Published; Peer Reviewed; Author Profile: FLETCHJ; DOI

Soares MV, Plunkett FJ, Verbeke CS, Cook JE, Faint JM, Belaramani LL, Fletcher JM, Hammerschmitt N, Rustin M, Bergler W, Beverley PC, Salmon M, Akbar AN., Integration of apoptosis and telomere erosion in virus-specific CD8+ T cells from blood and tonsils during primary infection., Blood., 103, (1), 2004, p162-167
Journal Article; Published; Peer Reviewed; Author Profile: FLETCHJ; DOI

O'Farrelly, C, Immunoregulation in the liver and its extrahepatic relevance., Journal of pediatric gastroenterology and nutrition, 39 Suppl 3, 2004, pS727-S728
Journal Article; Published; Peer Reviewed; Author Profile: OFARRECL; URL

Carton, J, Byrne, B, Madrigal-Estebas, L, O'Donoghue, DP, O'Farrelly, C, CD4+CD8+ human small intestinal T cells are decreased in coeliac patients, with CD8 expression downregulated on intra-epithelial T cells in the active disease., European journal of gastroenterology & hepatology, 16, (10), 2004, p961-8
Journal Article; Published; Peer Reviewed; Author Profile: OFARRECL; URL

Lynn, DJ, Lloyd, AT, Fares, MA, O'Farrelly, C, Evidence of positively selected sites in mammalian alpha-defensins., Molecular biology and evolution, 21, (5), 2004, p819-827
Journal Article; Published; Peer Reviewed; Author Profile: OFARRECL; DOI; URL

Golden-Mason, L, Douek, DC, Koup, RA, Kelly, J, Hegarty, JE, O'Farrelly, C, Adult human liver contains CD8pos T cells with naive phenotype, but is not a site for conventional alpha beta T cell development., Journal of immunology (Baltimore, Md. : 1950), 172, (10), 2004, p5980-5
Journal Article; Published; Peer Reviewed; Author Profile: OFARRECL; URL

Kelly, AM, Golden-Mason, L, McEntee, G, Traynor, O, Doherty, DG, Hegarty, JE, O'Farrelly, C, Interleukin 12 (IL-12) is increased in tumour bearing human liver and expands CD8(+) and CD56(+) T cells in vitro but not in vivo., Cytokine, 25, (6), 2004, p273-282
Journal Article; Published; Peer Reviewed; Author Profiles: DOHERTDE OFARRECL ; DOI; URL

Golden-Mason, L, Kelly, AM, Doherty, DG, Traynor, O, McEntee, G, Kelly, J, Hegarty, JE, O'Farrelly, C, Hepatic interleuklin 15 (IL-15) expression: implications for local NK/NKT cell homeostasis and development., Clinical and experimental immunology, 138, (1), 2004, p94-101
Journal Article; Published; Peer Reviewed; Author Profiles: OFARRECL DOHERTDE ; DOI; URL

O'Keeffe, J, Doherty, DG, Kenna, T, Sheahan, K, O'Donoghue, DP, Hyland, JM, O'Farrelly, C, Diverse populations of T cells with NK cell receptors accumulate in the human intestine in health and in colorectal cancer., European journal of immunology, 34, (8), 2004, p2110 - 2119
Journal Article; Published; Peer Reviewed; Author Profiles: OFARRECL DOHERTDE ; DOI; URL

Lynn, DJ, Higgs, R, Gaines, S, Tierney, J, James, T, Lloyd, AT, Fares, MA, Mulcahy, G, O'Farrelly, C, Bioinformatic discovery and initial characterisation of nine novel antimicrobial peptide genes in the chicken., Immunogenetics, 56, (3), 2004, p170-177
Journal Article; Published; Peer Reviewed; Author Profile: OFARRECL; DOI; URL

Varadarajan, R, Golden-Mason, L, Young, L, McLoughlin, P, Nolan, N, McEntee, G, Traynor, O, Geoghegan, J, Hegarty, JE, O'Farrelly, C, Nitric oxide in early ischaemia reperfusion injury during human orthotopic liver transplantation., Transplantation, 78, (2), 2004, p250-6
Journal Article; Published; Peer Reviewed; Author Profile: OFARRECL; URL

Kenna, T, Golden-Mason, L, Norris, S, Hegarty, JE, O'Farrelly, C, Doherty, DG, Distinct subpopulations of gamma delta T cells are present in normal and tumor-bearing human liver., Clinical immunology (Orlando, Fla.), 113, (1), 2004, p56-63
Journal Article; Published; Peer Reviewed; Author Profiles: OFARRECL DOHERTDE ; DOI; URL

Mansell, A, Brint E, Gould, JA, O'Neill, LA and Hertzog, P, Mal interacts with tumor necrosis factor receptor-associated factor (TRAF)-6 to mediate NF-kappaB activation by toll-like receptor (TLR)-2 and TLR4, Journal of Biological Chemistry, 279, (36), 2004, p37227 - 37230
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI

O'Neill LA, Toll-like receptors: Professor Metchnikov, sit on your hat, Trends in Immunol, 125, (12), 2004, p687 - 693
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Morozova OB, Yurkovskaya AV, Sagdeev RZ, Mok KH, Hore PJ, Time-Resolved CIDNP Study of Native-State Bovine and Human alpha-Lactalbumins, Journal of Physical Chemistry B, 108, (39), 2004, p15355 - 15363
Journal Article; Published; Peer Reviewed; Author Profile: MOK1

Picanco-Diniz, C.W., Boche, D., Gomes-Leal, W., Perry, V.H. and Cunningham, C., Neuropil and Neuronal changes in hippocampal NADPH-diaphorase histochemistry in the ME7 model of murine prion disease, Neuropathology and Applied Neurobiology, 30, 2004, p292-303
Journal Article; Published; Peer Reviewed; Author Profile: CUNNINCO; DOI

Mok KH, Hore PJ, Photo-CIDNP NMR methods for studying protein folding (Review), Methods, 34, (1), 2004, p75 - 87
Journal Article; Published; Peer Reviewed; Author Profile: MOK1; DOI

Aflatoxin Aldehyde Reductases in, editor(s)Penning TM, Petrash JM , Aldo-Keto Reductases and toxicant metabolism, Oxford, UK, Oxford University Press, 2004, pp155 - 170, [Kelly VP, O'Connor T, Ellis EM, Ireland LS, Slattery CM, Sherratt PJ, Crouch DH, Cavin C, Schilter B, Gallina A, Hayes JD]
Book Chapter; Published; Peer Reviewed; Author Profile: KELLYVP

Itoh K, Mochizuki M, Ishii Y, Ishii T, Shibata T, Kawamoto Y, Kelly VP, Sekizawa K, Uchida K, Yamamoto M., Transcription factor Nrf2 regulates inflammation by mediating the effect of 15-deoxy-prostaglandin J2, Molecular and Cellular Biology, 24, 2004, p36 - 45
Journal Article; Published; Peer Reviewed; Author Profile: KELLYVP; DOI

García-Salcedo J.A., Perez-Morga, D., Gijón P., Dilbeek, V., Pays, E. and Nolan, D.P., A differential role for actin in the life cycle of T. brucei., EMBO Journal, 25, 2004, p780 - 789
Journal Article; Published; Peer Reviewed; Author Profile: DENOLAN; DOI

Tipton KF, Boyce S, O'Sullivan J., Davey G.P. and Healy J., Monoamine Oxidases: Certainties and Uncertanties, Current Med. Chemistry , 11, 2004, p1965 - 1982
Journal Article; Published; Peer Reviewed; Author Profile: GDAVEY

O'Sullivan J, Unzeta M, Healy J, O'Sullivan MI, Davey G, Tipton KF, Semicarbazide-sensitive amine oxidases: enzymes with quite a lot to do, Neurotoxicology, 25, 2004, p303 - 315
Journal Article; Published; Peer Reviewed; Author Profile: GDAVEY

Farmer MK, Tipton KF and Davey GP, The effects of two salsolinol derivatives on mitochondrial respiration and the likely nature of any endogenous parkinsonism-inducing toxin. In Monoamine Oxidase inhibitors and their role in neurotransmission, In Monoamine Oxidase inhibitors and their role in neurotransmission, 2004, p42 - 55
Journal Article; Published; Peer Reviewed; Author Profile: GDAVEY

Mills, K.H.G., Keogh, B and McGuirk, P, Cell-based therapies., 2004, UK patent application
Patent; Published; Peer Reviewed; Author Profile: MILLSK

Mills, K.H.G., Keogh, B and McGuirk, P, Methods for suppressing immune responses to biological agents. , 2004, UK patent application
Patent; Submitted; Peer Reviewed; Author Profile: MILLSK

Carroll, A.M., Haines, L.R., Pearson, T.W., Brennan, C., Breen, E.P. & Porter R.K., Immunodetection of UCP 1 in Rat Thymus, Biochemical Society Transactions, 32, (6), 2004, p1066 - 1067
Journal Article; Published; Peer Reviewed; Author Profile: RKPORTER; URL

Lloyd DG, Hughes RB, Zisterer DM, Williams DC, Fattorusso C, Catalanotti B, Campiani G, Meegan MJ., Benzoxepin-derived estrogen receptor modulators: a novel molecular scaffold for the estrogen receptor, Journal of Medicinal Chemistry, 47, (23), 2004, p5612 - 5615
Journal Article; Published; Peer Reviewed; Author Profiles: DZISTRER MMEEGAN DWILLIMS ; DOI; URL

Mantle TJ & Noone P., Chromatofocusing, Methods Mol Biol, 244, 2004, p233 - 237
Journal Article; Published; Peer Reviewed; Author Profile: TMANTLE

Tetlow, N., Robinson , A., Mantle, T. & Board, P., Polymorphism of human Mu class glutathione transferases, Pharmacogenetics, 14 , 2004, p359 - 368
Journal Article; Published; Peer Reviewed; Author Profile: TMANTLE

O'NEILL LUKE A J (Trinity College Dublin); SIMS JOHN E (Immunex); BIRD TIMOTHY A (Immunex), MyD88 adaptor-like proteins, 2004, WO 01/088137
Patent; Published; Peer Reviewed; Author Profile: LAONEILL

Carroll, A.M., Haines, L.R., Pearson, T.W., Brennan, C., Breen, E. & Porter, R.K., Identification of a functioning uncoupling protein 1 in rat thymus, EBEC Short Report, 13, 2004, pp203
Conference Paper; Published; Peer Reviewed; Author Profile: RKPORTER

Carroll, A.M. & Porter, R.K., Starvation sensitive UCP 3 expression in rat thymus and spleen, Biochim. Biophys. Acta, 1700, 2004, p145 - 150
Journal Article; Published; Peer Reviewed; Author Profile: RKPORTER; URL

A. F. McGettrick and L. A. O'Neill, The expanding family of MyD88-like adaptors in Toll-like receptor signal transduction, Mol Immunol, 41, (6-7), 2004, p577-82
Journal Article; Published; Peer Reviewed; Author Profiles: LAONEILL MCGETTRA ; DOI; URL

C. A. Jefferies and L. A. O'Neill, Bruton's tyrosine kinase (Btk)-the critical tyrosine kinase in LPS signalling?, Immunology letters, 92, (38018), 2004, p15-22
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

L. A. O'Neill, Immunology. After the toll rush, Science, 303, (5663), 2004, p1481-2
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

E. K. Brint, D. Xu, H. Liu, A. Dunne, A. N. McKenzie, L. A. O'Neill and F. Y. Liew, ST2 is an inhibitor of interleukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance, Nature immunology, 5, (4), 2004, p373-379
Journal Article; Published; Peer Reviewed; Author Profiles: AIDUNNE LAONEILL ; DOI; URL

L. A. O'Neill, How NOD-ing off leads to Crohn disease, Nature immunology, 5, (8), 2004, p776-8
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

M. P. Hardy, G. A. F. Mc and L. A. O'Neill, Transcriptional regulation of the human TRIF (TIR domain-containing adaptor protein inducing interferon beta) gene, The Biochemical journal, 380, (Pt 1), 2004, p83-93
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; URL

M. P. Hardy and L. A. O'Neill, The murine IRAK2 gene encodes four alternatively spliced isoforms, two of which are inhibitory, The Journal of biological chemistry, 279, (26), 2004, p27699-708
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI

E. M. Palsson-McDermott and L. A. O'Neill, Signal transduction by the lipopolysaccharide receptor, Toll-like receptor-4, Immunology, 113, (2), 2004, p153-62
Journal Article; Published; Peer Reviewed; Author Profiles: PALSSONE LAONEILL ; DOI

M. M. Mc Gee, L. M. Greene, S. Ledwidge, G. Campiani, V. Nacci, M. Lawler, D. C. Williams and D. M. Zisterer, Selective induction of apoptosis by the pyrrolo-1,5-benzoxazepine 7-[[dimethylcarbamoyl]oxy]-6-(2-naphthyl)pyrrolo-[2,1-d] (1,5)-benzoxazepine (PBOX-6) in Leukemia cells occurs via the c-Jun NH2-terminal kinase-dependent phosphorylation and inactivation of Bcl-2 and Bcl-XL, The Journal of pharmacology and experimental therapeutics, 310, (3), 2004, p1084-1095
Journal Article; Published; Peer Reviewed; Author Profiles: DZISTRER DWILLIMS MPLAWLER ; DOI; URL

Palsson-McDermott EM and O'Neill LA, Signal transduction by the lipopolysacchride receptor Toll-like receptor-4, Immunology, 113, (2), 2004, p153 - 162
Journal Article; Published; Peer Reviewed; Author Profile: PALSSONE

DiPerna, G., Stack, J., Bowie, A.G., Boyd, A., Kotwal, G., Zhang, Z., Arvikar, S., Latz, E., Fitzgerald, K.A. & Marshall, W.L. , Poxvirus protein N1L targets the I-kappaB Kinase complex, inhibits signaling to NF-kappaB by the Tumor Necrosis Factor superfamily of receptors, and inhibits NF-kappaB and IRF3 signaling by Toll-like receptors. , The Journal of Biological Chemistry, 279, (35), 2004, p36570 - 36578
Journal Article; Published; Peer Reviewed; Author Profile: AGBOWIE; DOI; URL

Malmgaard, L., Melchjorsen, J., Bowie, A.G., Mogensen, S.C. & Paludan, S.R. , Viral activation of macrophages through TLR-dependent and -independent pathways., The Journal of Immunology, 173, (11), 2004, p6890 - 6898
Journal Article; Published; Peer Reviewed; Author Profile: AGBOWIE; URL

Lavelle EC., Grant G., Pfuller U. and O'Hagan D.T, Immunological implications of the use of plant lectins for drug and vaccine targeting to the gastrointestinal tract, The Journal of Drug Targeting , 12, (2), 2004, p89 - 95
Journal Article; Published; Peer Reviewed; Author Profile: LAVELLEE; DOI

Lavelle, E.C., McGuirk, P. and Mills, K.H.G. , Molecules of Infectious Agents as Immunomodulatory Drugs, Current Medicinal Chemistry , 4, (5), 2004, p499 - 508
Journal Article; Published; Peer Reviewed; Author Profiles: MILLSK LAVELLEE ; URL

Boyce, S., Tipton, K.F. and McDonald, A.G., Extending enzyme classification with metabolic and kinetic data: Some difficulties to be resolved. , 1st International Beilstein Workshop on Experimental Standard Conditions of Enzyme Characterizations. , Beilstein Institut, Frankfurt, Germany , 5-8 October 2003, edited by M.G. Hicks and C. Kettner , 2004, pp17 - 43
Conference Paper; Published; Peer Reviewed; Author Profile: KTIPTON

The effects of two salsolinol derivatives on mitochondrial respiration and the likely nature of any endogenous parkinsonism-inducing toxin. in, editor(s)T.L..Török & I. Klebovich , Design of Monoamine oxidase Inhibitors and their role in neurotransmission (drug development). , Budapest, Medicina Publishing House Co, 2004, pp55 - 77, [Farmer, M.K., Tipton, K.F. and Davey, G.P.]
Book Chapter; Published; Peer Reviewed; Author Profile: KTIPTON

Monoamine oxidases (MAO): Functions in the nervous system. in, editor(s)G. Adelman and B. Smith , Encyclopedia of Neuroscience, 3rd Edition, Amsterdam, Elsevier Science BV, 2004, pp1-17 , [Tipton, K.F., O'Sullivan, J. and Youdim, M.B.H.]
Book Chapter; Published; Peer Reviewed; Author Profile: KTIPTON

Bridge, M.H., Williams, E., Lyons, M.E., Tipton, K.F. and Linert. W., Electrochemical investigation into the redox activity of Fe(II)/Fe(III) in the presence of nicotine and possible relations to neurodegenerative diseases., BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 1690, (1), 2004, p77 - 84
Journal Article; Published; Peer Reviewed; Author Profile: KTIPTON

Colivicchi, M.A., Raimondi, L., Bianchi, L., Tipton, K.F., Pirisino, R. and Della Corte, L., Taurine prevents streptozotocin impairment of hormone-stimulated glucose uptake in rat adipocytes. , EUROPEAN JOURNAL OF PHARMACOLOGY, 495, (2-3), 2004, p209 - 215
Journal Article; Published; Peer Reviewed; Author Profile: KTIPTON

Tipton, K.F., Boyce, S., O'Sullivan, J., Davey, G.P. and Healy, J., Monoamine oxidases: certainties and uncertainties , Current Medicinal Chemistry , 11, 2004, p1965 - 1982
Journal Article; Published; Peer Reviewed; Author Profile: KTIPTON

K.H.G. Mills, Regulatory T cells: friend or foe in immunity to infection. , Nature Reviews Immunology, 4, 2004, p841 - 855
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI

Hill MM, Adrain C, Duriez PJ, Creagh EM, Martin SJ, Analysis of the composition, assembly kinetics and activity of native Apaf-1 apoptosomes, EMBO JOURNAL, 23, (10), 2004, p2134 - 2145
Journal Article; Published; Peer Reviewed; Author Profiles: ECREAGH MARTINSJ ; DOI; URL

Creagh EM, Murphy BM, Duriez PJ, Duckett CS, Martin SJ, Smac/Diablo antagonizes ubiquitin ligase activity of inhibitor of apoptosis proteins, JOURNAL OF BIOLOGICAL CHEMISTRY, 279, (26), 2004, p26906 - 26914
Journal Article; Published; Peer Reviewed; Author Profiles: MARTINSJ ECREAGH ; DOI; URL

Adrain C, Creagh EM, Cullen SP, Martin SJ, Caspase-dependent inactivation of proteasome function during programmed cell death in Drosophila and man, JOURNAL OF BIOLOGICAL CHEMISTRY, 279, (35), 2004, p36923 - 36930
Journal Article; Published; Peer Reviewed; Author Profiles: ECREAGH MARTINSJ ; DOI; URL

Murphy BM, Creagh EM, Martin SJ, Interchain proteolysis, in the absence of a dimerization stimulus, can initiate apoptosis-associated caspase-8 activation, JOURNAL OF BIOLOGICAL CHEMISTRY, 279, (35), 2004, p36916 - 36922
Journal Article; Published; Peer Reviewed; Author Profiles: ECREAGH MARTINSJ ; DOI; URL

Brint EK, Xu DM, Liu HY, Dunne A, McKenzie ANJ, O'Neill LAJ, Liew FY, ST2 is an inhibitor of interleukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance, NATURE IMMUNOLOGY, 5, (4), 2004, p373 - 379
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Hardy MP, McGettrick AF, O'Neill LAJ, Transcriptional regulation of the human TRIF (TIR domain-containing adaptor protein inducing interferon beta) gene, Biochemical Journal, 380, (1), 2004, p83 - 93
Journal Article; Published; Peer Reviewed; Author Profiles: LAONEILL MCGETTRA ; URL

Khan JA, Brint EK, O'Neill LAJ, Tong L, Crystal structure of the Toll/interleukin-1 receptor domain of human IL-1RAPL, Journal of Biological Chemistry, 279, (30), 2004, p31664 - 31670
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI

Kiss-Toth E, Bagstaff SM, Sung HY, Jozsa V, Dempsey C, Caunt JC, Oxley KM, Wyllie DH, Polgar T, Harte M, O'Neill LAJ, Qwarnstrom EE, Dower SK, Human tribbles, a protein family controlling mitogen-activated protein kinase cascades, Journal of Biological Chemistry, 279, (41), 2004, p42703 - 42708
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI

Lavelle EC, Jarnicki A, McNeela E, Armstrong ME, Higgins SC, Leavy O, Mills KHG, Effects of cholera toxin on innate and adaptive immunity and its application as an immunomodulatory agent, Journal of Leukocyte Biology, 75, (5), 2004, p756 - 763
Journal Article; Published; Peer Reviewed; Author Profiles: LAVELLEE ARMSTRP MILLSK ; DOI

Byrne P, McGuirk P, Todryk S, Mills KHG, Depletion of NK cells results in disseminating lethal infection with Bordetella pertussis associated with a reduction of antigen-specific Th1 and enhancement of Th2, but not Tr1 cells, EUROPEAN JOURNAL OF IMMUNOLOGY, 34, (9), 2004, p2579 - 2588
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI; URL

Bowe, F., Lavelle, E.C., McNeela, E. A., Hale, C., Clare, S., Arico, B., Giuliani, M.M., Rae, A., Huett, A., Rappuoli, R., Dougan, G. and Mills, K. H.G., Mucosal vaccination against serogroup B meningococcus:Induction of bactericidal antibodies and cellular immunity following intranasal immunization with NadA of Neisseria meningitidis and mutants of Escherichia coli heat-labile enterotoxin, Infection and Immunity, 72, (7), 2004, p4052 - 4060
Journal Article; Published; Peer Reviewed; Author Profiles: MILLSK LAVELLEE ; DOI

Mills, K.H.G. and McGuirk, P., Antigen-specific regulatory T cells - their induction and role in infection, Seminars in Immunology, 16, (2), 2004, p107 - 117
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; URL

Ross, P.J., Lavelle, E.C., Mills, K.H.G. and A.P. Boyd., Adenylate cyclase toxin from Bordetella pertussis synergises with lipopolysaccharide to promote innate IL-10 production and enhance the induction of Th2 and regulatory T cells, Infection and Immunity, 72, (3), 2004, p1568 - 1579
Journal Article; Published; Peer Reviewed; Author Profiles: MILLSK LAVELLEE ; DOI

McNeela, E., Jabbal-Gill, E. Illum, L., Pizza, Rappuoli, R., Podda, A., Lewis, D.M. and Mills, K.H.G., Intranasal immunization with genetically detoxified diphtheria toxin induces T cell responses in humans: correlation between toxin neutralizing antibody and Th2 responses, VACCINE, 22, (8), 2004, p909 - 914
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI; URL

Lavelle, E., McGuirk and Mills, K.H.G., Molecules of infectious agents as immunomodulatory drugs, Current Topics in Med. Chem., 4, (5), 2004, p499 - 508
Journal Article; Published; Peer Reviewed; Author Profiles: MILLSK LAVELLEE ; URL

Hardy, M, McGettrick, A and O'Neill, LAJ , Transcriptional regulation of the human TRIF (TIR domain-containing adaptor protein inducing interferon beta) gene., Biochemical Journal, 380, (1), 2004, p83 - 93
Journal Article; Published; Peer Reviewed; Author Profiles: MCGETTRA LAONEILL ; DOI

Irwin, J. A. and Tipton, K. F., Affinity precipitation methods, Methods Mol Biol, 244, 2004, p205 - 224
Journal Article; Published; Peer Reviewed; Author Profile: KTIPTON

Fleischmann, A., Darsow, M., Degtyarenko, K., Fleischmann, W., Boyce, S., Axelsen, K. B., Bairoch, A., Schomburg, D., Tipton, K. F. and Apweiler, R., IntEnz, the integrated relational enzyme database, Nucleic Acids Res, 32, 2004, pD434 - 477
Journal Article; Published; Peer Reviewed; Author Profile: KTIPTON

Bianchi, L., De Micheli, E., Bricolo, A., Ballini, C., Fattori, M., Venturi, C., Pedata, F., Tipton, K. F. and Della Corte, L., Extracellular levels of amino acids and choline in human high grade gliomas: an intraoperative microdialysis study, NEUROCHEMICAL RESEARCH, 29, (1), 2004, p325 - 334
Journal Article; Published; Peer Reviewed; Author Profile: KTIPTON

O'Sullivan, J., Unzeta, M., Healy, J., O'Sullivan, M. I., Davey, G., and Tipton, K. F.,, Semicarbazide-Sensitive Amine Oxidases: Enzymes with Quite a Lot to Do, Neurotoxicology, 25, 2004, p303 - 315
Journal Article; Published; Peer Reviewed; Author Profile: KTIPTON

Bowie, A.G., Zhan, J. & Marshall, W.L., Viral Appropriation of Apoptotic and NF-kappaB Signalling Pathways, Journal of Cell Biology, 91, (6), 2004, p1099 - 1108
Journal Article; Published; Peer Reviewed; Author Profile: AGBOWIE; DOI; URL