Publications
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60 publications from 2002
Cherezov, V. and Qiu, H. and Pector, V. and Vandenbranden, M. and Ruysschaert, J.-M. and Caffrey, M., Biophysical and transfection studies of the diC
Brzustowicz, M.R. and Cherezov, V. and Caffrey, M. and Stillwell, W. and Wassall, S.R., Molecular organization of cholesterol in polyunsaturated membranes: Microdomain formation, Biophysical Journal, 82, (1), 2002, p285-298
Cherezov, V. and Clogston, J. and Misquitta, Y. and Abdel-Gawad, W. and Caffrey, M., Membrane protein crystallization in meso: Lipid type-tailoring of the cubic phase, Biophysical Journal, 83, (6), 2002, p3393-3407
Shoshani T, Faerman A, Mett I, Zelin E, Tenne T, Gorodin S, Moshel Y, Elbaz S, Budanov A, Chajut A, Kalinski H, Kamer I, Rozen A, Mor O, Keshet E, Leshkowitz D, Einat P, Skaliter R, Feinstein E, Identification of a novel hypoxia-inducible factor 1-responsive gene, RTP801, involved in apoptosis., Molecular and Cellular Biology, 22, (7), 2002, p2283 - 2293
Budanov AV, Shoshani T, Faerman A, Zelin E, Kamer I, Kalinski H, Gorodin S, Fishman A, Chajut A, Einat P, Skaliter R, Gudkov AV, Chumakov PM, Feinstein E, Identification of a novel stress-responsive gene Hi95 involved in regulation of cell viability., Oncogene, 21, (39), 2002, p6017 - 6031
Coles B, Bloodsworth A, Eiserich JP, Coffey MJ, McLoughlin RM, Giddings JC, Lewis MJ, Haslam RJ, Freeman BA, O'Donnell VB, Nitrolinoleate inhibits platelet activation by attenuating calcium mobilization and inducing phosphorylation of vasodilator-stimulated phosphoprotein through elevation of cAMP., The Journal of biological chemistry, 277, (8), 2002, p5832-40
Hurst SM, McLoughlin RM, Monslow J, Owens S, Morgan L, Fuller GM, Topley N, Jones SA, Secretion of oncostatin M by infiltrating neutrophils: regulation of IL-6 and chemokine expression in human mesothelial cells., Journal of immunology (Baltimore, Md. : 1950), 169, (9), 2002, p5244-51
*Lantto J, *Fletcher JM, Ohlin M. , A divalent antibody format is required for neutralization of human cytomegalovirus via antigenic domain 2 on glycoprotein B, Journal of General Virology, 83, (8), 2002, p2001-2005
Dunne PJ, Faint JM, Gudgeon NH, Fletcher JM, Plunkett FJ, Soares MV, Hislop AD, Annels NE, Rickinson AB, Salmon M, Akbar AN., Epstein-Barr virus-specific CD8(+) T cells that re-express CD45RA are apoptosis-resistant memory cells that retain replicative potential., Blood, 100, (3), 2002, p933-940.
Taams, L.S., Vukmanovic-Stejic, M., Smith, J., Dunne, P.J., Fletcher, J.M., Plunkett, F.J., Ebeling, S.B., (...), Akbar, A.N., 17. Taams LS, Vukmanovic-Stejic M, Smith J, Dunne PJ, Fletcher JM, Plunkett FJ, Ebeling SB, Lombardi G, Rustin MH, Bijlsma JW, Lafeber FP, Salmon M, Akbar AN. Antigen-specific T cell suppression by human CD4+CD25+ regulatory T cells., European Journal of Immunology, 32, (6), 2002, p1621-1630
D. Brady, S. Gaines, L. Fenelon, J. Mc Partlin, C. O'Farrelly, A lipoprotein derived antimicrobial factor from hen egg yolk is active against Streptococcus species, J Food Sci , 67, (8), 2002, p3096-3103
Golden-Mason, L, O'Farrelly, C, Having it all? Stem cells, haematopoiesis and lymphopoiesis in adult human liver., Immunology and cell biology, 80, (1), 2002, p45-51
Madrigal-Estebas, L, Doherty, DG, O'Donoghue, DP, Feighery, C, O'Farrelly, C, Differential expression and upregulation of interleukin-1alpha, interleukin-1beta and interleukin-6 by freshly isolated human small intestinal epithelial cells., Mediators of inflammation, 11, (5), 2002, p313-319
Deignan, T, Curry, MP, Doherty, DG, Golden-Mason, L, Volkov, Y, Norris, S, Nolan, N, Traynor, O, McEntee, G, Hegarty, JE, O'Farrelly, C, Decrease in hepatic CD56(+) T cells and V alpha 24(+) natural killer T cells in chronic hepatitis C viral infection., Journal of Hepatology, 37, (1), 2002, p101-8
Byrne, B, Madrigal-Estebas, L, McEvoy, A, Carton, J, Doherty, DG, Whelan, A, Feighery, C, O'Donoghue, DP, O'Farrelly, C, Human duodenal epithelial cells constitutively express molecular components of antigen presentation but not costimulatory molecules., Human immunology, 63, (11), 2002, p977-86
Cunningham, C., Boche, D. and Perry, V.H., Transforming growth factor b1, the dominant cytokine in murine prion disease: influence on inflammatory cytokine synthesis and alteration of vascular extracellular matrix. , Neuropath Appl. Neurobiol. , 28, 2002, p107-119
Combrinck, M.I., Perry, V.H. and Cunningham C., Peripheral infection evokes exaggerated sickness behaviour in pre-clinical murine prion disease, Neuroscience., 112, 2002, p7-11
Perry, V.H., Cunningham, C. and Boche, Atypical inflammation in the central nervous system in prion disease, Current Opinion in Neurology , 15, 2002, p349-354
Robert Dantzer(ed.), Cytokines in the ageing brain, Trends in Neurosciences, Arcachon, France, 25, ((11)), June 2002, Elsevier, 2002, 546-547 p
Kelly VP, Sherratt PJ, Crouch DH and Hayes JD, Novel homodimeric and heterodimeric rat gamma-hydroxybutyrate synthases that associate with the Golgi apparatus define a distinct class of aldo-keto reductase 7 family proteins, Biochemical Journal, 366, (3), 2002, p847 - 861
Arai T, Kelly VP, Minowa O, Noda T and Nishimura S, High accumulation of oxidative DNA damage, 8-hydroxyguanine, in Mmh/Ogg1 deficient mice by chronic oxidative stress, Carcinogenesis, 23, 2002, p2005 - 2010
Shilling HG, Guethlein LA, Chenng NW, Gardiner CM, Rodriguez R, Tyan D and Parham P, KIR allelic polymorphism is a major component of KIR haplotype diversity, Journal of Immunology, 168, 2002, p2307 - 2315
Shilling HG, Guethlein LA, Cheng NW, Gardiner CM, Tyan D and Parham P, Genetic control of human NK cell repertoires, Journal of Immunology, 169, 2002, p239 - 247
Shields DC, Fitzgerald AP, O'Neill PA, Muckian C, Kenny D, Moran B, Cannon CP, Byrne CE, Fitzgerald DJ., The contribution of genetic factors to thrombotic and bleeding outcomes in coronary patients randomised to IIb/IIIa antagonists, Pharmacogenomics Journal, 2, (3), 2002, p182 - 190
Gomez-Lozano N, Gardiner CM, Parham P and Vilches C, Some KIR haplotypes contain two KIR2DL5 genes: KIR2DL5A and KIR2DL5B, Immunogenetics, 54, 2002, p314 - 319
Campiani, G., Ramuno, A., Fiorini, I., Nacci, V., Morelli, E., Novellino, E., Menninni, T., Zisterer, D.M., Williams, D.C. , Synthesis of new molecular probes for investigation of steroid biosynthesis induced by selective interaction with peripheral-type benzodiazepine receptors (PBR)., Journal Medicinal Chemistry, 45, (19), 2002, p4276 - 4281
Quinlan, C.A., O'Sullivan, M.I., Zisterer, D.M. & Tipton, K.F., In vitro cytotoxicity of a composite resin and compomer., International Endodontic Journal, 35, (1), 2002, p47 - 55
Garcia-Salcedo, J.A., Nolan, D.P., Gijon-Martin, P., Gomez, J., and Pays, E., A protein kinase specifically associated with proliferative forms of Trypanosoma brucei is functionally related to a yeast kinase involved in the co-ordination of cell shape and division, Mol. Microbiol, 45, 2002, p307 - 319
Brint, E.K., Fitzgerald, K.A., Smith, P., Coyle, A.J., Gutierrez-Ramos, J-C., Fallon, P.G. & O'Neill, L.A.J., Characterization of signaling pathways activated by the interleukin 1 (IL-1) receptor homologue T1/ST2. A role for Jun N-terminal kinase in IL-4 induction, Journal of Biological Chemistry, 277, (51), 2002, p49205 - 49211
MANTLE, TJ, HAEM DEGRADATION IN ANIMALS AND PLANTS, BIOCHEMICAL SOCIETY TRANSACTIONS, 30, 2002, p630 - 633
Brennan, C.M, McElligott, A.M. Warmington, S.A. & Porter, R.K., Skeletal muscle uncoupling protein-3 expression following endurance swimming training in mice, Proceedings of the Journal of Physiology, 543, 2002, pp119
L. A. O'Neill, Toll-like receptor signal transduction and the tailoring of innate immunity: a role for Mal?, Trends in immunology, 23, (6), 2002, p296-300
V. Corrigall and L. A. O'Neill, Using immunotherapy to treat rheumatic diseases, Trends in immunology, 23, (8), 2002, p383-384
L. A. O'Neill, Wanted: a molecular basis for specificity in toll-like receptor signal transduction, Molecular cell, 10, (5), 2002, p969-971
L. A. O'Neill, Signal transduction pathways activated by the IL-1 receptor/toll-like receptor superfamily, Current Topics in Microbiology and Immunology, 270, 2002, p47-61
E. P. McDermott and L. A. O'Neill, Ras participates in the activation of p38 MAPK by interleukin-1 by associating with IRAK, IRAK2, TRAF6, and TAK-1, The Journal of Biological Chemistry, 277, (10), 2002, p7808-7815
M. M. Mc Gee, G. Campiani, A. Ramunno, V. Nacci, M. Lawler, D. C. Williams and D. M. Zisterer, Activation of the c-Jun N-terminal kinase (JNK) signaling pathway is essential during PBOX-6-induced apoptosis in chronic myelogenous leukemia (CML) cells, The Journal of Biological Chemistry, 277, (21), 2002, p18383-18389
M. M. Mc Gee, E. Hyland, G. Campiani, A. Ramunno, V. Nacci and D. M. Zisterer, Caspase-3 is not essential for DNA fragmentation in MCF-7 cells during apoptosis induced by the pyrrolo-1,5-benzoxazepine, PBOX-6, FEBS letters, 515, (1-3), 2002, p66-70
Eva Palsson-McDermott and Luke A.J. O'Neill, Ras participates in the activation of p38 MAPK by Interleukin-1 by associating with IRAK, IRAK2, TRAF6, and TAK-1, The Journal of Biological Chemistry, 277, (10), 2002, p7808 - 7815
Brennan, C.M. McElligott, A.M., Warmington, S.A. and Porter, R.K., Skeletal muscle uncoupling protein-3 expression following endurance swimming training in mice, Proceedings of the Physiological Society, The Journal of Physiology, University of Liverpool, July, 543, (P), 2002, pp119p
O'Hagan, D.T and Lavelle, E. , Novel adjuvants and delivery systems for HIV vaccines, AIDS, 16, 2002, pS115 - S124
Caspase cascades in apoptosis in, editor(s)M. Los and H. Walczak , In Caspases-Their role in Cell Death and Cell Survival, New York, USA, Landes Bioscience/Kluwer Academic/Plenum Publishers, 2002, pp41 - 51, [S.J Martin]
Wietek, C and O'Neill, LAJ , IRAK-4: a new drug target in inflammation, sepsis and autoimmunity, Molecular Interventions, 2, (4), 2002, p212 - 215
Peter McGuirk, Chantelle McCann, and Kingston H.G. Mills, Pathogen-specific T Regulatory 1 Cells Induced in the Respiratory Tract by a Bacterial Molecule that Stimulates Interleukin 10 Production by Dendritic Cells: A Novel Strategy for Evasion of Protective T Helper Type 1 Responses by Bordetella pertussis, Journal of Experimental Medicine , 195, (2), 2002, p221 - 231
McGuirk, P and Mills K.H.G., PATHOGEN-SPECIFIC REGULATORY T CELLS PROVOKE A SHIFT IN THE TH1/TH2 PARADIGM IN IMMUNITY TO INFECTIOUS DISEASES, TRENDS IN IMMUNOLOGY, 23, 2002, p450-455
Lavelle EC, Grant G, Pusztai A, Pfüller U, Leavy O, McNeela E, Mills KH, O'Hagan DT., Mistletoe lectins enhance immune responses to intranasally co-administered herpes simplex virus glycoprotein D2., Journal of Immunology, 107, (2), 2002, p268 - 274
MILLS, KHG, LIVE VECTORS: ARE SAFE BUT EFFECTIVE VACCINES POSSIBLE?, 2002, - 854-855
MACDONALD, AJ, CD4 T HELPER TYPE 1 AND REGULATORY T CELLS INDUCED AGAINST THE SAME EPITOPES ON THE CORE PROTEIN IN HEPATITIS C VIRUS-INFECTED PERSONS, JOURNAL OF INFECTIOUS DISEASES, 185, 2002, p720 - 727
Keogh, B., Atkins, G.J., Mills, K.H.G., Sheahan, B.J, Avirulent Semliki Forest virus replication and pathology in the central nervous system is enhanced in IL-12-defective and reduced in IL-4-defective mice: A role for Th1 cells in the protective immunity , Journal of Neuroimmunology , 125, 2002, p15 - 22
Della Corte, L., Crichton, R. R., Duburs, G., Nolan, K., Tipton, K. F., Tirzitis, G. and R.J, The use of taurine analogues to investigate taurine functions and their potential therapeutic applications, Amino Acids , 23, 2002, p367 - 379
Biogenic amines. diet and the properties of amine oxidases in, editor(s)D. M. L. Morgan, T. Hirvi, G. Dandrifosse, P. Deloyer and A. White , Biogenically Active Amines in Food, Brussels, Belgium , European Communities Publication Office, , 2002, pp117 - 121, [Tipton, K. F.]
Principles of enzyme assay and kinetic studies in, editor(s)R, Eisenthal and M.J. Danson , Enzyme Assays: A Practical Approach , Oxford University Press , 2002, pp1 - 47, [K.F. Tipton]
O'Byrne, M. B. and Tipton, K. F. , Inhibition of the neuronal isoform of nitric oxide synthase significantly attenuates 1-methyl-4-phenylpyridinium (MPP+) toxicity in vitro, J. Neural Transm, 109, 2002, p585 - 596
Youdim, M. B. H. and Tipton, K. F., Rat striatal monoamine oxidase-B inhibition by l-deprenyl and rasagiline: its relationship to 2-phenylethylamine-induced stereotypy and Parkinson's disease. , Parkinsonism Relat. Disord, 8, 2002, p247 - 253
Youdim, M. B. H. and K.F. Tipton, K. F., Rat striatal monoamine oxidase-B inhibition by l-deprenyl and rasagiline: its relationship to 2-phenylethylamine-induced stereotypy and Parkinson's disease. , Parkinsonism Relat. Disord, 8, 2002, p247 - 253
Fitzgerald, D. H. and K. F. Tipton, K. F., Inhibition of monoamine oxidase modulates the behaviour of semicarbazide-sensitive amine oxidase (SSAO). , J. Neural Transm, 109, 2002, p251-265
O'Sullivan, M., Tipton, K. F. and McDevitt, W. E. , Immunolocalization of semicarbazide-sensitive amine oxidase in human dental pulp and its activity towards serotonin, Oral Biol, 47, 2002, p399 - 406
Hayes, J. P. and Tipton, K. F., Interactions of the neurotoxin 6-hydroxydopamine with glyceraldehyde-3-phosphate dehydrogenase, Toxicology Letters , 128, 2002, p197-206
Quinlan, C. A., Zisterer, D. M., Tipton, K. F. and O'Sullivan, M. I., A study of the in vitro cytotoxicity of a composite resin and compomer , Int. Endod. J., 35, 2002, p47 - 55
Chen M, Stafford W, Diedrich G, Khan AR and Bouvier M, A characterization of the lumenal region of human tapasin reveals the presence of two structural domains., Biochemistry, 41, (49), 2002, p14539 - 14545