Publications
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83 publications from 2001
Koh, D., Park, K.H., Jung, J., Yang, H., Hun Mok, K., Lim, Y., Complete assignment of the1H and13C NMR spectra of resveratrol derivatives, Magnetic Resonance in Chemistry, 39, (12), 2001, p768-770
) Endocytosis of macromolecules by African trypanosomes in, editor(s)Eds. Seed, R. & Black, S.J. (Kluwer Academic Publishers) , "World Class Parasites Volume 1: The African Trypanosomes", (Kluwer Academic Publishers) , 2001, pp127 - 141, [Nolan, DP, Garcia-Salcedo, J.A., Geuskens, M., Salmon, D., Paturiaux-Hanocq, F., Pays, A., Tebabi, P. and Pays, E. ]
Cherezov, V. and Fersi, H. and Caffrey, M., Crystallization screens: Compatibility with the lipidic cubic phase for in meso crystallization of membrane proteins, Biophysical Journal, 81, (1), 2001, p225-242
Misquitta, Y. and Caffrey, M., Rational design of lipid molecular structure: A case study involving the C19:1c10 monoacylglycerol, Biophysical Journal, 81, (2), 2001, p1047-1058
Koynova, R. and Caffrey, M., Erratum: Phases and phase transitions of the phosphatidylcholines (Biochimica et Biophysica Acta (1998) 1376 (91-145) PII: S0304415798000069), Biochimica et Biophysica Acta - Biomembranes, 1513, (1), 2001, p82
Smirnov AS, Ruzov AS, Budanov AV, Prokhortchouk AV, Ivanov AV, Prokhortchouk EB, High constitutive level of NF-kappaB is crucial for viability of adenocarcinoma cells., Cell Death and Differentiation, 8, (6), 2001, p621 - 630
Hurst S.M, Wilkinson T.S, McLoughlin R.M, Jones S, Horiuchi S, Yamamoto N, Rose-John S, Fuller G.M, Topley N, Jones S.A, IL-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation, Immunity, 14, (6), 2001, p705 - 714
Bouchier-Hayes L, Conroy H, Egan H, Adrain C, Creagh EM, MacFarlane M, Martin SJ, CARDINAL, a novel caspase recruitment domain protein, is an inhibitor of multiple NF-kappa B activation pathways., The Journal of biological chemistry, 276, (47), 2001, p44069-77
Robson RL, McLoughlin RM, Witowski J, Loetscher P, Wilkinson TS, Jones SA, Topley N, Differential regulation of chemokine production in human peritoneal mesothelial cells: IFN-gamma controls neutrophil migration across the mesothelium in vitro and in vivo., Journal of immunology (Baltimore, Md. : 1950), 167, (2), 2001, p1028-38
Doherty, D.G., O'Farrelly, C., Dendritic cells: Regulators of hepatic immunity or tolerance?, Journal of Hepatology, 34, (1), 2001, p156-160
Dunne J, Lynch S, O'Farrelly C, Hegarty JE, Feighery C, Doherty DG., Selective expansion and partial activation of human NK cells and NK receptor-positive T cells by IL-2 and IL-15. , Journal of Immunology, 167, (6), 2001, p3129-3138
Lavelle, E.C., Chiron Corporation, Plant lectins as mucosal adjuvants. , 2001, WO0134193
Rajalingam R, Gardiner CM, Canavez F, Vilches C and Parham P, Identification of seventeen novel KIR variants: fourteen of them from two non-Caucasian donors, Tissue Antigens, 57, 2001, p22 - 31
T.Deignan, A. Alwan, L. Malone, J. Kelly, C. O'Farrelly. , Hen egg yolk prevents bacterial adherence: a novel function for a familiar food. , J Food Sci , 66, 2001, p158-161
Golden-Mason, L, Kelly, AM, Traynor, O, McEntee, G, Kelly, J, Hegarty, JE, O'Farrelly, C, Expression of interleukin 7 (IL-7) mRNA and protein in the normal adult human liver: implications for extrathymic T cell development., Cytokine, 14, (3), 2001, p143-51
Dunne, J, Lynch, S, O'Farrelly, C, Todryk, S, Hegarty, JE, Feighery, C, Doherty, DG, Selective expansion and partial activation of human NK cells and NK receptor-positive T cells by IL-2 and IL-15., Journal of immunology (Baltimore, Md. : 1950), 167, (6), 2001, p3129-38
Drudy, D, O'Donoghue, DP, Baird, A, Fenelon, L, O'Farrelly, C, Flow cytometric analysis of Clostridium difficile adherence to human intestinal epithelial cells., Journal of medical microbiology, 50, (6), 2001, p526-34
Grant A, Staffas L, Mancowiz L, Kelly VP, Manson MM, DePierre JW, Hayes JD, Ellis EM, Expression of rat aldehyde reductase AKR7A1: influence of age and sex and tissue-specific inducibility, Biochemal Pharmacology, 62, (11), 2001, p1511 - 1519
Gardiner CM, Guethlein LA, Shilling HG, Pando M, carr WH, Rajalingam R, Vilches C and Parham P, Different NK cell surface phenotypes defined by the DX9 antibody are due to KIR3DL1 gene polymorphism, Journal of Immunology, (166), 2001, p2992 - 3001
Meegan, M., Hughes, R., Lloyd, D.G., Zisterer, D.M. & Williams, D.C. , Flexible estrogen receptor modulators: design, synthesis and antagonistic effects in human MCF-7 breast cancer cells. , Journal Medicinal Chemistry, 44, (7), 2001, p1072 - 1084
Black, S.J., N. Murphy and D. Nolan, Innate and acquired control of trypanosomiasis in Cape buffalo, Int. J. Parasitol., 31, 2001, p562 - 565
Pays, E. Lips, S., Nolan, D., Vanhamme, L., and Pérez-Morga D., The VSG expression site of Trypanosoma brucei: multipurpose tools for the adaptation of the parasite to various mammalian hosts, Mol. Biochem. Parasitol., 114, 2001, p1 - 16
Endocytosis of macromolecules by African trypanosomes in, editor(s)Seed, R. & Black, S.J. , World Class Parasites Volume 1: The African Trypanosomes, Kluwer Academic Publishers, 2001, pp127 - 141, [Nolan, DP, Garcia-Salcedo, J.A., Geuskens, M., Salmon, D., Paturiaux-Hanocq, F., Pays,A., Tebabi, P. and Pays, E.]
Towards a trypanosoiasis vaccine in, editor(s)Seed, R. & Black, S.J. , World Class Parasites Volume 1: The African Trypanosomes, Kluwer Academic Publishers, 2001, pp159 - 174, [Black, S.J., Murphy, N.B. and Nolan, D.P.]
PEREIRA, PJB, MACEDO-RIBEIRO, S, PARRAGA, A, PEREZ-LUQUE, R, CUNNINGHAM, O, DARCY, K, MANTLE, TJ, COLL, M, STRUCTURE OF HUMAN BILIVERDIN IX BETA REDUCTASE, AN EARLY FETAL BILIRUBIN IX BETA PRODUCING ENZYME, NATURE STRUCTURAL BIOLOGY, 8, 2001, p215 - 220
MANTLE, TJ, ENZYMES: NATURE'S NANOMACHINES, BIOCHEMICAL SOCIETY TRANSACTIONS, 29, 2001, p331 - 336
Maguire, D.J., Joyce, O. & Porter, R.K., Mitoprotein separation on 2-D Native Blue Gels; Miniaturization and resolution of extraction artefacts, Human Genetics Society of Australasia Meeting, 2001
Cunningham, O, Carroll, A.M. & Porter R.K., RT-PCR evidence for the expression of UCP-2 in spleen and murine macrophage cell line (J774), 674th Biochemical Society Meeting, 29, 2001, pp119
Breen, E.P. & Porter, R.K., Discriminatory antibody raised to UCP-3 used to detect protein in a number of systems, 674th Biochemical Society Meeting, 29, 2001, pp120
Porter, R.K., Mitochondrial Proton Leak: A Role for Uncoupling Proteins 2 & 3 ?, Biochim. Biophys. Acta, 1504, (1), 2001, p120 - 127
Porter, R.K., Allometry of mammalian cellular oxygen consumption, Cellular and Molecular Life Sciences, 58, 2001, p815 - 822
M. M. Mc Gee, G. Campiani, A. Ramunno, C. Fattorusso, V. Nacci, M. Lawler, D. C. Williams and D. M. Zisterer, Pyrrolo-1,5-benzoxazepines induce apoptosis in chronic myeloid leukemia (cml) cells by bypassing the apoptotic suppressor bcr-abl, TheScientificWorldJournal [electronic resource], 1, (1 Suppl 3), 2001, p109
M. M. Mc Gee, G. Campiani, A. Ramunno, C. Fattorusso, V. Nacci, M. Lawler, D. C. Williams and D. M. Zisterer, Pyrrolo-1,5-benzoxazepines induce apoptosis in chronic myelogenous leukemia (CML) cells by bypassing the apoptotic suppressor bcr-abl, The Journal of pharmacology and experimental therapeutics, 296, (1), 2001, p31-40
L. O'Neill, Specificity in the innate response: pathogen recognition by Toll-like receptor combinations, Trends in immunology, 22, (2), 2001, p70
O'Neill, LAJ, Toll-like receptors and the danger hypothesis, Trends in Immunology, 22, (8), 2001, p421
E. Dunn, J. E. Sims, M. J. Nicklin and L. A. O'Neill, Annotating genes with potential roles in the immune system: six new members of the IL-1 family, Trends in Immunology, 22, (10), 2001, p533-536
K. A. Fitzgerald, E. M. Palsson-McDermott, A. G. Bowie, C. A. Jefferies, A. S. Mansell, G. Brady, E. Brint, A. Dunne, P. Gray, M. T. Harte, D. McMurray, D. E. Smith, J. E. Sims, T. A. Bird and L. A. O'Neill, Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction, Nature, 413, (6851), 2001, p78-83
C. Jefferies, A. Bowie, G. Brady, E. L. Cooke, X. Li and L. A. O'Neill, Transactivation by the p65 subunit of NF-kappaB in response to interleukin-1 (IL-1) involves MyD88, IL-1 receptor-associated kinase 1, TRAF-6, and Rac1, Molecular and Cellular Biology, 21, (14), 2001, p4544-4552
A. Mansell, N. Khelef, P. Cossart and L. A. O'Neill, Internalin B activates nuclear factor-kappa B via Ras, phosphoinositide 3-kinase, and Akt, The Journal of Biological Chemistry, 276, (47), 2001, p43597-43603
A. Mansell, A. Reinicke, D. M. Worrall and L. A. O'Neill, The serine protease inhibitor antithrombin III inhibits LPS-mediated NF-kappaB activation by TLR-4, FEBS letters, 508, (3), 2001, p313-317
M. Marangolo, M. M. McGee, K. F. Tipton, D. C. Williams and D. M. Zisterer, Oxidative stress induces apoptosis in C6 glioma cells: involvement of mitogen-activated protein kinases and nuclear factor kappa B, Neurotox Research, 3, (4), 2001, p397-409
M. M. Mc Gee, G. Campiani, A. Ramunno, C. Fattorusso, V. Nacci, M. Lawler, D. C. Williams and D. M. Zisterer, Pyrrolo-1,5-benzoxazepines induce apoptosis in chronic myelogenous leukemia (CML) cells by bypassing the apoptotic suppressor bcr-abl, The Journal of Pharmacology and Experimental Therapeutics, 296, (1), 2001, p31-40
D. M. Zisterer, M. M. McGee, G. Campiani, A. Ramunno, C. Fattorusso, V. Nacci, M. Lawler and D. C. Williams, Pyrrolo-1,5-benzoxazepines: a new class of apoptotic agents, Biochemical Society transactions, 29, (6), 2001, p704-706
Fitzgerald KA, Palsson-McDermott EM, et al, Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction, Nature, 413, (6851), 2001, p78 - 83
Lavelle, E.C., Grant, G., Pusztai,A., Pfüller,U and O'Hagan, D.T. , The identification of plant lectins with mucosal adjuvant activity, Immunology, 102, (1), 2001, p77 - 86
Lavelle, E.C, Targeted delivery of drugs to the gastrointestinal tract, CRC Critical Reviews in Therapeutic Drug Carrier Systems, 18, (4), 2001, p341 - 386
P.A. Johnson, M. Conway, J. Daly, C. Nicolson J. Robertson K.H.G. Mills., Influenza HA DNA induces Th1 cells and protection despite limited antibody responses. Options for the Control of Influenza virus., International Congress Series , 1219, 2001, pp911-915
O'Neill, Mills, K.H.G. and Dalton, J.P., Fasciola hepatica cathepsin L cysteine proteinase suppresses Bordetella pertussis-specific IFN-gamma production in vivo, Parasite Immunol., 23, (10), 2001, p541 - 548
McNeela, E. and Mills, K.H.G., Manipulating the immune system - humoral versus cell-mediated immunity, Advanced Drug Delivery Reviews, 51, 2001, p41 - 52
Ryan, E.R., Daly, L. and Mills K.H.G., Immunomodulators and delivery systems for vaccination by mucosal routes, Trends Biotech., 19, (8), 2001, p293 - 304
Pizza, M., Giuliani, M.M., M.R. Fontana, E. Monacai, G. Douce, G. Dougan, K.H.G. Mills, R. Rappuoli, and G. Del Giudice., Mucosal vaccines: non toxic derivatives of LT and CT as mucosal adjuvants, Vaccine, 19, 2001, p2534 - 2541
Mills, K.H.G., Review: Immunity to Bordetella pertussis, Microbes and Infection, 3, 2001, p293 - 304
O'Neill, L.A.J, A gene for Crohn's disease is given the nod, Trends in Pharmacological Sciences, 22, (8), 2001, p398 - 399
O'Neill, L.A.J, A role for leptin in autoimmunity, Trends in Pharmacological Sciences, 22, (7), 2001, p341
O'Neill, L.A.J, Crohn's disease gene is given the NOD, Trends in Immunology, 22, (8), 2001, p418 - 419
O'Neill, L.A.J, Vaccine safety concerns, Trends in Immunology, 22, (8), 2001, p420 - 421
O'Neill, L.A.J, Irish say no to Nice but yes to immunology, Trends in Immunology, 22, (8), 2001, p421
O'Neill, L.A.J, A vaccine for colorectral cancer, Trends in Immunology, 22, (7), 2001, p354
O'Neill, L.A.J, IL-1 versus TNF in arthritis?. , Trends in Immunology, 22, (7), 2001, p353-354
O'Neill, L.A.J, Gob genes, mucus and asthma. , Trends in Immunology, 22, (7), 2001, p353
O'Neill, L.A.J, A role for leptin in autoimmunity? , Trends in Immunology, 22, (7), 2001, p352
O'Neill, L.A.J, An AIDS vaccine in sight? , Trends in Immunology, 22, (5), 2001, p242
O'Neill, L.A.J, Co-stimulating allergy, Trends in Immunology, 22, (4), 2001, p183
O'Neill, L.A.J, A roll-call of monocytic gene induction, Trends in Immunology, 22, (4), 2001, p182
O'Neill, LAJ, Fitzgerald, K, Gearing, AJH and Callard, R, Cytokine Factsbook, 2nd, London, U.K, Academic Press, 2001, 513pp
O'Neill, L.A.J. and Bowie, A.G. (editors) , Interleukin Protocols, New Jersey, USA, Methods in Molecular Medicine Series, Humana Press, 2001, 443pp
O'Neill, LAJ (Chair) and organising committee , Biochemical Society meeting, 2001, TCD
Creagh EM, Martin SJ, Caspases: cellular demolition experts., BIOCHEMICAL SOCIETY TRANSACTIONS, 29, 2001, p696 - 702
Adrain C, Creagh EM, Martin SJ, Apoptosis-associated release of Smac/DIABLO from mitochondria requires active caspases and is blocked by Bcl-2, THE EMBO JOURNAL, 20, 2001, p6627 - 6636
Commins S, O'Neill LA, O'Mara SM., The effects of the bacterial endotoxin lipopolysaccharide on synaptic transmission and plasticity in the CA1-subiculum pathway in vivo., Neuroscience, 102, (2), 2001, p273 - 280
BRINT, B, T1/ST2 SIGNAL TRANSDUCTION: ACTIVATION OF AP-1, JNK, P38 AND P42/P44 MAP KINASE BUT NOT NF-KAPPAB, unknown, 2001, ISI Web of Science, 2001, pp58 - 58
FITZGERALD, KA, MAL (MYD88 ADAPTER-LIKE) IS REQUIRED FOR TOLL-LIKE RECEPTOR-4 SIGNAL TRANSDUCTION, unknown, 2001, ISI Web of Science, 2001, pp33 - 33
CONWAY, MA, PROTECTION AGAINST BORDETELLA PERTUSSIS INFECTION FOLLOWING PARENTERAL OR ORAL IMMUNIZATION WITH ANTIGENS ENTRAPPED IN BIODEGRADABLE PARTICLES: EFFECT OF FORMULATION AND ROUTE OF IMMUNIZATION ON INDUCTION OF TH1 AND TH2 CELLS, VACCINE, 19, 2001, p1940 - 1950
Meegan MJ, Hughes RB, Lloyd DG, Williams DC, Zisterer DM, Ethyl side-chain modifications in novel flexible antiestrogens--design, synthesis and biological efficacy in assay against the MCF-7 breast tumor cell line, Anticancer Drug Design , 16, (1), 2001, p57 - 69
Amine Oxidases and the metabolism of xenobiotics in, editor(s)C. Ioannides , Enzyme Systems that Metabolise Drugs and Other Xenobiotics, Chichester, UK , John Wiley & Sons, Ltd, 2001, pp95 -146 , [Tipton, K. F. and Strolin Benedetti, M.]
McDonald, A. G., Boyce, S., Connolly, J., Kazic, T., Wise, W. and Tipton, K. F., Metabolic systems and the behaviour of neuronal systems, Proceedings of the First World Congress of Neuroinfomatics, Vienna, Austria, edited by F. Rattay , Argesima/ASIM Verlag, 2001, pp308 - 316
Cunningham, C. and Strolin Benedetti, M. , Oxidative stress and radical detection, Food Antioxidants and Human Health (EC FAIR Conference)., Siena, Italy , edited by G. Sgaragli and M. Valoti , Casa Editrice I Mori, 2001, pp47 - 56
Marangolo, M., Tipton, K. F., McGee, M. M., Williams D. C. and Zisterer, D. M., Oxidative stress induces apoptosis in C6 glioma cells: involvement of mitogen-activated protein kinase and nuclear factor kappa B, Neurotoxicity Res, 3, 2001, p397 - 409
Hayes, J., Tipton, K. F., Bianchi, L. and Della Corte, L., Complexities in the neurotoxic actions of 6-hydroxydopamine in relation to thecytoprotective properties of taurine, Brain Research Bulletin, 55, 2001, p239-245
Alcohol and Alcoholism , (2001), Tipton, K. F., [Chief ed.], 1996-2001
O'Neill, LAJ and Bowie, A (eds.), Interleukin protocols, New Jersey, The Humana Press Inc, 2001
Sheila Donnelly, Christine E. Loscher, Marina A. Lynch, and Kingston H. G. Mills, Whole-cell but not acellular pertussis vaccines induce convulsive activity in mice: evidence of a role for toxin-induced interleukin-1 beta in a new murine model for analysis of neuronal side effects of vaccination, Infection and Immunity, 69, (7), 2001, p4217 - 4223
Kelly Á, Lynch A. Vereker E, Nolan Y, Queenan P, Whittaker E, O' Neill LAJ, Lynch MA. , The anti-inflammatory cytokine, interleukin (IL)-10, blocks the inhibatory effect of IL-1 beta on long term potentiation - a role for JNK, Journal of Biological Chemistry, 276, (49), 2001, p45564 - 45572