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Publications

Below is the list of peer and non peer publications from the School of Biochemistry and Immunology.

Show: AllPeer ReviewedNon Peer Reviewed
101 publications from 2000

Cho, J.-H., Mok, K.H., Olivera, B.M., McIntosh, J.M., Park, K.-H., Han, K.-H., Nuclear magnetic resonance solution conformation of "-conotoxin AuIB, an "3ß4 subtype-selective neuronal nicotinic acetylcholine receptor antagonist, Journal of Biological Chemistry, 275, (12), 2000, p8680-8685
Journal Article; Published; Peer Reviewed; Author Profile: MOK1; DOI

Park, J., Chung, I.H., Kim, J.H., Kim, C.S., Mok, K.H., Lim, Y., Structural study of N-(1-benzoyl-3-pyrrolidinyl) benzamide, Spectroscopy Letters, 33, (6), 2000, p777-793
Journal Article; Published; Peer Reviewed; Author Profile: MOK1

Ai, X. and Caffrey, M., Membrane protein crystallization in lipidic mesophases: Detergent effects, Biophysical Journal, 79, (1), 2000, p394-405
Journal Article; Published; Peer Reviewed; Author Profile: MCAFFRE; DOI; URL

Neverova ME, Budanov AV, Adamskaia EI, Prasolov VS, Kalinin ME, Construction by using retrovirus vector of recombinant with synthetic bradykinin "gene" for investigations of human gene expression in mammalian cells., Vestnik Rossiiskoi akademii meditsinskikh nauk, 5, 2000, p33 - 35
Journal Article; Published; Peer Reviewed; Author Profile: BUDANOVA

Smirnov AS, Budanov AV, Ruzov AS, Ivanov AV, Prokhorchuk AV, Gnuchev NV, Prokhorchuk EB, A high constitutive level of NF-kappa B is necessary for viability of murine adenocarcinoma cells--possible role of p53, Molecular Biology, 35, (5), 2000, p775 - 782
Journal Article; Published; Peer Reviewed; Author Profile: BUDANOVA; URL

Kane, P., Kincaid, K., Fayne, D., Diamond, D., McKervey, M.A., Modelling metal complexes of calixarene esters and phosphine oxides using molecular mechanics, Journal of Molecular Modeling, 6, (2), 2000, p272-281
Journal Article; Published; Peer Reviewed; Author Profile: FAYNED

Creagh EM, Carmody RJ, Cotter TG, Heat shock protein 70 inhibits caspase-dependent and -independent apoptosis in Jurkat T cells., Experimental cell research, 257, (1), 2000, p58-66
Journal Article; Published; Peer Reviewed; Author Profile: ECREAGH

Creagh E.M., Sheehan D. and Cotter T.G. , Heat shock proteins - modulators of apoptosis in tumour cells, Leukemia , 14, 2000, p1161-1173
Review Article; Published; Peer Reviewed; Author Profile: ECREAGH

Lee HS, Chung J-S, Chung K-T, Mok KH, Kim K-W, Ha S-H, Koh HK, Kim HS, Cheil Jedang Corporation, Homogeneous and Cost-Efficient Purification of Human G-CSF using Preparative Reverse-Phase HPLC, 2000
Patent; Published; Peer Reviewed; Author Profile: MOK1

Ha S-H, Koh HK, Oh MS, Kim HS, Chung K-T, Lee HS, Mok KH, Cheil Jedang Corporation, Molecular cloning, engineering, and expression of human granulocyte colony stimulating factor (G-CSF), 2000, Registered Republic of Korea Patent No. 0262867
Patent; Published; Peer Reviewed; Author Profile: MOK1

Aisling Dunne, Orla Cunningham, Timothy Mantle, Studies on the specificity of the tetrapyrrole substrate for human biliverdin-IXalpha reductase and biliverdin-IXbeta reductase. Structure-activity relationships define models for both active sites, Journal of Biological chemistry, 275, 2000, p19009-
Journal Article; Published; Peer Reviewed; Author Profile: AIDUNNE

Caffrey, M, A lipid's eye view of membrane protein crystallization in mesophases., Current Opinion in Structural Biology, 10, (4), 2000, p486-497
Journal Article; Published; Peer Reviewed; Author Profile: MCAFFRE; DOI

Redpath MB, Windle H, Nolan D, Pays E, Voorheis HP, Carrington M, ESAG11, a new VSG expression site-associated gene from Trypanosoma brucei., Molecular and biochemical parasitology, 111, (1), 2000, p223-228
Journal Article; Published; Peer Reviewed; Author Profiles: HJWINDLE DENOLAN ; DOI

Doherty, D.G., O'Farrelly, C., Innate and adaptive lymphoid cells in the human liver , Immunological Reviews, 174, (1), 2000, p5-20
Review Article; Published; Peer Reviewed; Author Profiles: OFARRECL DOHERTDE ; DOI

K. A. Fitzgerald, A. G. Bowie, B. S. Skeffington and L. A. O'Neill, Ras, protein kinase C zeta, and I kappa B kinases 1 and 2 are downstream effectors of CD44 during the activation of NF-kappa B by hyaluronic acid fragments in T-24 carcinoma cells, Journal of Immunology, 164, (4), 2000, p2053-2063
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL

Vilches C, Rajalingam R, Uhrberg M, Gardiner CM, Young N and Parham P, KIR2DL5, a novel killer-cell receptor with a D0-D2 configuration of immunoglobulin-like domains, Journal of Immunology, 164, 2000, p5797 - 5804
Journal Article; Published; Peer Reviewed; Author Profile: GARDINEC

Vilches C, Pando M, Rajalingam R, Gardiner CM and Parham P, Discovery of two novel variants of KIR2DS5 reveals this gene to be a common component of the human KIR 'B' haplotypes, Tissue Antigens, 56, 2000, p453 - 456
Journal Article; Published; Peer Reviewed; Author Profile: GARDINEC

Vilches C, Gardiner CM and Parham P, Gene structure and promoter variation of expressed and non-expressed variants of the KIR2DL5 gene, Journal of Immunology, 165, 2000, p6416 - 6421
Journal Article; Published; Peer Reviewed; Author Profile: GARDINEC

T. Deignan, J. Kelly, A. Alwan, C. O'Farrelly. , Comparative analysis of methods of purification of egg yolk immunoglobin (IgY). , Food Agric Immunol, 12, 2000, p77-85
Journal Article; Published; Peer Reviewed; Author Profile: OFARRECL; URL

O'Farrelly, C, Is villous atrophy always and only the result of gluten sensitive disease of the intestine?, European journal of Gastroenterology & Hepatology, 12, (6), 2000, p605-8
Journal Article; Published; Peer Reviewed; Author Profile: OFARRECL

Curry, MP, Golden-Mason, L, Nolan, N, Parfrey, NA, Hegarty, JE, O'Farrelly, C, Expansion of peripheral blood CD5+ B cells is associated with mild disease in chronic hepatitis C virus infection., Journal of Hepatology, 32, (1), 2000, p121-5
Journal Article; Published; Peer Reviewed; Author Profile: OFARRECL; DOI; URL

Flynn, L, Byrne, B, Carton, J, Kelehan, P, O'Herlihy, C, O'Farrelly, C, Menstrual cycle dependent fluctuations in NK and T-lymphocyte subsets from non-pregnant human endometrium., American journal of reproductive immunology (New York, N.Y. : 1989), 43, (4), 2000, p209-17
Journal Article; Published; Peer Reviewed; Author Profile: OFARRECL; DOI; URL

Deignan, T, Alwan, A, Kelly, J, McNair, J, Warren, T, O'Farrelly, C, Serum haptoglobin: an objective indicator of experimentally-induced Salmonella infection in calves., Research in veterinary science, 69, (2), 2000, p153-8
Journal Article; Published; Peer Reviewed; Author Profile: OFARRECL; DOI; URL

Curry, MP, Norris, S, Golden-Mason, L, Doherty, DG, Deignan, T, Collins, C, Traynor, O, McEntee, GP, Hegarty, JE, O'Farrelly, C, Isolation of lymphocytes from normal adult human liver suitable for phenotypic and functional characterization., Journal of Immunological Methods, 242, (1-2), 2000, p21-31
Journal Article; Published; Peer Reviewed; Author Profiles: OFARRECL DOHERTDE ; DOI

Golden-Mason, L, Curry, MP, Nolan, N, Traynor, O, McEntee, G, Kelly, J, Hegarty, JE, O'Farrelly, C, Differential expression of lymphoid and myeloid markers on differentiating hematopoietic stem cells in normal and tumor-bearing adult human liver., Hepatology (Baltimore, Md.), 31, (6), 2000, p1251-6
Journal Article; Published; Peer Reviewed; Author Profile: OFARRECL; DOI; URL

Cho J-H, Mok KH, Olivera BM, McIntosh JM, Park K-H, Han K-H, NMR Solution Conformation of Alpha-Conotoxin AuIB, an Alpha3Beta4 Subtype-Selective Neuronal Nicotinic Acetylcholine Receptor Antagonist, Journal of Biological Chemistry, 275, (12), 2000, p8680 - 8685
Journal Article; Published; Peer Reviewed; Author Profile: MOK1

Lee H, Mok KH, Muhandiram DR, Park K-H, Suk J-E, Kim D-H, Chang J, Sung YC, Choi KW, Han K-H, Local Structural Elements in the Mostly Unstructured Transcriptional Activation Domain of Human p53, Journal of Biological Chemistry, 275, (38), 2000, p29426 - 29432
Journal Article; Published; Peer Reviewed; Author Profile: MOK1

Minghetti, L., Greco, A., Cardone, F., Puopolo, M., Ladogana, A., Almonti, S., Cunningham, C., Perry, V. H., Pocchiari, M. and Levi, G., ncreased brain synthesis of prostaglandin E2 and F2-isoprostane in human and experimental transmissible spongiform encephalopathies, Journal of Neuropathology and Experimental Neurology, 59, ((10)), 2000, p866-871
Journal Article; Published; Peer Reviewed; Author Profile: CUNNINCO

Kelly VP, Ireland LS, Ellis EM and Hayes JD, Purification from rat liver of a novel constitutively expressed member of the aldo-keto reductase 7 family that is widely distributed in extra-hepatic tissues, Biochemical Journal, 348, (2), 2000, p389 - 400
Journal Article; Published; Peer Reviewed; Author Profile: KELLYVP; DOI

Kelly VP, Ellis EM, Manson MM, Chanas S A, Graeme JM, McLeod R, Neal GE and Hayes JD, Chemoprevention of aflatoxin B1 hepato-carcinogenesis by coumarin, a natural benzopyrone that is a potent inducer of Aflatoxin B1-Aldehyde Reductase, the Glutathione S-Transferase A5 and P1 Subunits and NAD(P)H:Quinone Oxidoreductase in Rat Liver, Cancer Research, 60, (4), 2000, p957 - 969
Journal Article; Published; Peer Reviewed; Author Profile: KELLYVP; URL

Nolan, D. & Voorheis, H. P., Hydrogen ion gradients across the mitochondrial, endosomal and plasma membranes in bloodstream forms of Trypanosoma brucei - Solving the three-compartment problem, European Journal of Biochemistry, 267, (15), 2000, p4601 - 4614
Journal Article; Published; Peer Reviewed; Author Profile: DENOLAN; DOI

Nolan, D. & Voorheis, H. P., Factors that determine the plasma membrane potential in bloodstream forms of Trypanosoma brucei, European Journal of Biochemistry, 267, (15), 2000, p4615 - 4623
Journal Article; Published; Peer Reviewed; Author Profile: DENOLAN; DOI

Nolan, D.P., Jackson, D.G., Biggs, M.J., Brabazon, E.D., Pays, A., Van Laethem, F., Paturiaux-Hanocq, F., (...), Pays, E., Characterization of a novel alanine-rich protein located in surface microdomains in Trypanosoma brucei , Journal of Biological Chemistry, 275, (6), 2000, p4072 - 4080
Journal Article; Published; Peer Reviewed; Author Profile: DENOLAN; DOI

Zisterer, D.M., Campiani., Nacci, V. & Williams, D.C. , Pyrrolobenzoxazepines induce apoptosis in HL-60, Jurkat and Hut-78 cells: A new class of apoptotic agents., Journal Pharmacology and Experimental Therapeutics, 293, (1), 2000, p48 - 59
Journal Article; Published; Peer Reviewed; Author Profiles: DWILLIMS DZISTRER ; URL

Nolan, D.P., Rolin, S., Rodriguez, J. R., Van Den Abbeele, J. and Pays, E., Slender and stumpy bloodstream forms of Trypanosoma brucei display a differential response to extracellular acidic and proteolytic stress, Eur. J. Biochem., 267, 2000, p18 - 27
Journal Article; Published; Peer Reviewed; Author Profile: DENOLAN

Paturiaux-Hanocq, F., Hanocq-Quertier, J., Cardoso de Almeida, L., Nolan, D.P., Pays, A., Vanhamme, L., Van den Abbeele, J., Carrington, M. and Pays, E., A role for the dynamic acylation of a cluster of cysteine residues in regulating the activity of the glycosylphosphatidylinositol-specific phospholipase C of Trypanosoma brucei, J. Biol. Chem., 275, 2000, p12147 - 12155
Journal Article; Published; Peer Reviewed; Author Profile: DENOLAN

Redpath, M.B., Windle, H., Nolan, D., Pays, E., Voorheis, H.P., & Carrington, M., ESAG11, a new VSG expression site-associated gene from Trypanosoma brucei, Mol. Biochem. Parasitol., 111, 2000, p223 - 228
Journal Article; Published; Peer Reviewed; Author Profile: DENOLAN

Radwanska, M., Magez, S., Dumont, N., Pays, A., Nolan, D., and Pays, E., Antibodies raised against the flagellar pocket fraction of Trypanosoma brucei preferentially recognize HSP60 in a cDNA expression library, Parasit. Immunol, 22, 2000, p639 - 650
Journal Article; Published; Peer Reviewed; Author Profile: DENOLAN

NOLAN, DP, VOORHEIS, HP, HYDROGEN ION GRADIENTS ACROSS THE MITOCHONDRIAL, ENDOSOMAL AND PLASMA MEMBRANES IN BLOODSTREAM FORMS OF TRYPANOSOMA BRUCEI - SOLVING THE THREE-COMPARTMENT PROBLEM, EUROPEAN JOURNAL OF BIOCHEMISTRY, 267, 2000, p4601 - 4614
Journal Article; Published; Peer Reviewed; Author Profile: DENOLAN

NOLAN, DP, VOORHEIS, HP, FACTORS THAT DETERMINE THE PLASMA-MEMBRANE POTENTIAL IN BLOODSTREAM FORMS OF TRYPANOSOMA BRUCEI, EUROPEAN JOURNAL OF BIOCHEMISTRY, 267, 2000, p4615 - 4623
Journal Article; Published; Peer Reviewed; Author Profile: DENOLAN

NOLAN, DP, JACKSON, DG, BIGGS, MJ, BRABAZON, ED, PAYS, A, VAN LAETHEM, F, PATURIAUX-HANOCQ, F, ELLIOT, JF, VOORHEIS, HP, PAYS, E, CHARACTERIZATION OF A NOVEL ALANINE-RICH PROTEIN LOCATED IN SURFACE MICRODOMAINS IN TRYPANOSOMA BRUCEI, JOURNAL OF BIOLOGICAL CHEMISTRY, 275, 2000, p4072 - 4080
Journal Article; Published; Peer Reviewed; Author Profile: DENOLAN

Davey G.P. and Tipton K.F. , Mitochondria, Cell Death and DNA Damage, Radiation Research , (2), 2000, p390 - 394
Journal Article; Published; Peer Reviewed; Author Profile: GDAVEY

Gill, I.J., Lin,W., Jenkins,P., Watts,P., Jiminez,M., Illum,L., Davis,S.S., Wood,J.M., Major,D., Minor,P.D., Li,X., Lavelle,E.C. and Coombes,A.G.A. , Potential of polymeric lamellar substrate particles (PLSP) as adjuvants for vaccines, Vaccine, 18, (3-4), 2000, p238 - 250
Journal Article; Published; Peer Reviewed; Author Profile: LAVELLEE; DOI

Lavelle E.C, Targeted mucosal delivery of drugs and vaccines, Expert Opinion on Therapeutic Patents , 10, (2), 2000, p179 - 190
Journal Article; Published; Peer Reviewed; Author Profile: LAVELLEE; DOI

Lavelle E.C, Patent update on drug delivery: January-June, Expert Opinion on Therapeutic Patents , 10, (9), 2000, p1335 - 1343
Journal Article; Published; Peer Reviewed; Author Profile: LAVELLEE

Lavelle, E.C., Grant, G., Pusztai,A., Pfüller,U and O'Hagan, D.T. , Mucosal immunogenicity of plant lectins in mice., Immunology, 99, (1), 2000, p30 - 37
Journal Article; Published; Peer Reviewed; Author Profile: LAVELLEE; DOI

Spectrophotometric assays in, editor(s)M.G. Gore , Spectrophotomety and spectrofluorimetry, Oxford, Oxford University Press, 2000, pp183 - 208, [Mantle, T.J. & Harris]
Book Chapter; Published; Peer Reviewed; Author Profile: TMANTLE

CUNNINGHAM, O, DUNNE, A, SABIDO, P, LIGHTNER, D, MANTLE, TJ, STUDIES ON THE SPECIFICITY OF THE TETRAPYRROLE SUBSTRATE FOR HUMAN BILIVERDIN-IX ALPHA REDUCTASE AND BILIVERDIN-IX BETA REDUCTASE - STRUCTURE-ACTIVITY RELATIONSHIPS DEFINE MODELS FOR BOTH ACTIVE SITES, JOURNAL OF BIOLOGICAL CHEMISTRY, 275, 2000, p19009 - 19017
Journal Article; Published; Peer Reviewed; Author Profile: TMANTLE

CUNNINGHAM, O, GORE, MG, MANTLE, TJ, INITIAL-RATE KINETICS OF THE FLAVIN REDUCTASE REACTION CATALYSED BY HUMAN BILIVERDIN-IX BETA REDUCTASE (BVR-B), BIOCHEMICAL JOURNAL, 345, 2000, p393 - 399
Journal Article; Published; Peer Reviewed; Author Profile: TMANTLE

Palmi M., Youmbi G., Sgaragli G.P., Meini A., Benocci A., Fusi F., Frosini M., Della Corte L., Davey G. P. and Tipton K.F., Advances in Experimental Medicine and Biology, 483, 2000, p87 - 96
Journal Article; Published; Peer Reviewed; Author Profile: GDAVEY

Porter, R.K., Mammalian mitochondria; inner membrane cationic and neutral amino acid carriers, Biochim. Biophys. Acta, 1459, 2000, p356 - 362
Journal Article; Published; Peer Reviewed; Author Profile: RKPORTER; URL

L. A. O'Neill, The interleukin-1 receptor/Toll-like receptor superfamily: signal transduction during inflammation and host defense, Science's STKE [electronic resource], 2000, (44), 2000, pRE1
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

D. R. Caffrey, L. A. O'Neill and D. C. Shields, A method to predict residues conferring functional differences between related proteins: application to MAP kinase pathways, Protein Science, 9, (4), 2000, p655-670
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; URL

A. Bowie, E. Kiss-Toth, J. A. Symons, G. L. Smith, S. K. Dower and L. A. O'Neill, A46R and A52R from vaccinia virus are antagonists of host IL-1 and toll-like receptor signaling, Proceedings of the National Academy of Sciences of the United States of America, 97, (18), 2000, p10162-10167
Journal Article; Published; Peer Reviewed; Author Profiles: LAONEILL AGBOWIE ; DOI; URL

K. A. Fitzgerald and L. A. O'Neill, The role of the interleukin-1/Toll-like receptor superfamily in inflammation and host defence, Microbes and infection / Institut Pasteur, 2, (8), 2000, p933-943
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

J. M. O'Sullivan, A. Gribbin, J. Taylor, L. O'Neill, S. Cosgrove and J. G. Armstrong, Complications of treatment with local field external beam radiotherapy for localized prostate cancer, Clinical Oncology (Royal College of Radiologists (Great Britain)), 12, (4), 2000, p217-221
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

A. Mansell, L. Braun, P. Cossart and L. A. O'Neill, A novel function of InIB from Listeria monocytogenes: activation of NF-kappaB in J774 macrophages, Cellular microbiology, 2, (2), 2000, p127-136
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

B. White, M. Schmidt, C. Murphy, W. Livingstone, D. O'Toole, M. Lawler, L. O'Neill, D. Kelleher, H. P. Schwarz and O. P. Smith, Activated protein C inhibits lipopolysaccharide-induced nuclear translocation of nuclear factor kappaB (NF-kappaB) and tumour necrosis factor alpha (TNF-alpha) production in the THP-1 monocytic cell line, British Journal of Haematology, 110, (1), 2000, p130-134
Journal Article; Published; Peer Reviewed; Author Profiles: LAONEILL KELLEHDP ; DOI; URL

L. O'Neill, The Toll/interleukin-1 receptor domain: a molecular switch for inflammation and host defence, Biochemical Society Transactions, 28, (5), 2000, p557-563
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; URL

A. Bowie and L. A. O'Neill, Oxidative stress and nuclear factor-kappaB activation: a reassessment of the evidence in the light of recent discoveries, Biochemical pharmacology, 59, (1), 2000, p13-23
Journal Article; Published; Peer Reviewed; Author Profiles: LAONEILL AGBOWIE ; DOI; URL

A. Bowie and L. A. O'Neill, The interleukin-1 receptor/Toll-like receptor superfamily: signal generators for pro-inflammatory interleukins and microbial products, Journal of Leukocyte Biology, 67, (4), 2000, p508-514
Journal Article; Published; Peer Reviewed; Author Profiles: AGBOWIE LAONEILL ; URL

E. J. Ryan, E. McNeela, M. Pizza, R. Rappuoli, L. O'Neill and K. H. Mills, Modulation of innate and acquired immune responses by Escherichia coli heat-labile toxin: distinct pro- and anti-inflammatory effects of the nontoxic AB complex and the enzyme activity, Journal of Immunology (Baltimore, Md, 165, (10), 2000, p5750-9
Journal Article; Published; Peer Reviewed; Author Profiles: MILLSK LAONEILL ; URL

K. A. Fitzgerald, A. G. Bowie, B. S. Skeffington and L. A. O'Neill, Ras, protein kinase C zeta, and I kappa B kinases 1 and 2 are downstream effectors of CD44 during the activation of NF-kappa B by hyaluronic acid fragments in T-24 carcinoma cells, Journal of Immunology , 164, (4), 2000, p2053-2063
Journal Article; Published; Peer Reviewed; Author Profiles: LAONEILL AGBOWIE ; URL

A. G. Bowie and L. A. O'Neill, Vitamin C inhibits NF-kappa B activation by TNF via the activation of p38 mitogen-activated protein kinase, Journal of Immunology, 165, (12), 2000, p7180-7188
Journal Article; Published; Peer Reviewed; Author Profiles: AGBOWIE LAONEILL ; URL

M. P. Boland, K. A. Fitzgerald and L. A. O'Neill, Topoisomerase II is required for mitoxantrone to signal nuclear factor kappa B activation in HL60 cells, The Journal of Biological Chemistry, 275, (33), 2000, p25231-25238
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI

C. A. Jefferies and L. A. O'Neill, Rac1 regulates interleukin 1-induced nuclear factor kappaB activation in an inhibitory protein kappaBalpha-independent manner by enhancing the ability of the p65 subunit to transactivate gene expression, The Journal of Biological Chemistry, 275, (5), 2000, p3114-3120
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; URL

E. M. Palsson, M. Popoff, M. Thelestam and L. A. O'Neill, Divergent roles for Ras and Rap in the activation of p38 mitogen-activated protein kinase by interleukin-1, The Journal of Biological Chemistry, 275, (11), 2000, p7818-7825
Journal Article; Published; Peer Reviewed; Author Profiles: PALSSONE LAONEILL ; URL

L. A. O'Neill and C. A. Dinarello, The IL-1 receptor/toll-like receptor superfamily: crucial receptors for inflammation and host defense, Immunology today, 21, (5), 2000, p206-209
Journal Article; Published; Peer Reviewed; Author Profile: LAONEILL; DOI; URL

Eva M Palsson,Michael Popoff, Monica Thelestam,Luke O'Neill, Divergent Roles for Ras and Rap in the Activation of p38 MAPK by Interleukin-1, The Journal of Biological Chemistry, 275, (11), 2000, p7818 - 7825
Journal Article; Published; Peer Reviewed; Author Profile: PALSSONE; URL

Fisch, P., Mills, K.H.G. and vanMeerwijk, J.P.M., Molecular Determinants of T cell Immunity, The Immunologist, 8, 2000, pp114 - 118
Conference Paper; Published; Peer Reviewed; Author Profile: MILLSK

McGuirk P. and Mills K.H.G., Local cellular immunity to infection in the respiratry tract, Mucosal Immunology Update, 8, (2), 2000, pp8 - 10
Conference Paper; Published; Peer Reviewed; Author Profile: MILLSK

Mills, K.H.G. , A murine model for control and new developments in pertussis vaccination, Pharmeuropa, Biological beyond 2000. Proceedings of International Conference on 'Challenge for quality standards in an evolving field', Council of Europe, Strasburg, France, 2000, pp205 - 210
Conference Paper; Published; Peer Reviewed; Author Profile: MILLSK

McNeela, EA, O'Connor, D., Jabbal-Gill, I., Illum, L., Davis, S.S., Pizza, M., Peppoloni, S., Rappuoli, R. and Mills, K.H.G., A mucosal vaccine against diphtheria: Formulation of cross reacting material (CRM197) of diphtheria toxin with chitosan enhances local and systemic antibody and Th2 responses following nasal delivery, Vaccine, 19, (9-10), 2000, p1188 - 1198
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI; URL

McGuirk P. Johnson, Ryan, E.J. and Mills K.H.G., Filamentous Haemagglutinin and pertussis toxin from Bordetella pertussis modulate immune responses to unrelated antigens, J. Infect. Dis., 182, 2000, p1286 - 1288
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI; URL

Ryan E.J., Nilsson, L, Kjellman, N.-I. M., Gothefors, L and Mills K.H.G., Booster immunization of children with an acellular pertussis vaccine enhances Th2 cytokine production and serum IgE against pertussis toxin but not against common allergens, Clinical and Experimental Immunology, 121, (2), 2000, p193 - 200
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI

Johnson, P.A., Conway, M., Daly, J., Nicolson C., Robertson J. and Mills K.H.G., Plasmid DNA coding for influenza virus haemagglutinin induces Th1 cells and protection against respiratory infection despite its limited ability to generate antibody responses, Journal of General Virology, 81, 2000, p1737-1745
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; URL

Mahon, B.P., Brady, M.T. and Mills, K. H. G., Protection against Bordetella pertussis in mice in the absence of circulating antibody; implications for long term immunity in children, J. Infect. Dis., 181, 2000, p2087 - 2091
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI; URL

McGuirk, P. and Mills, K.H.G., Direct anti-inflammatory effect of a bacterial virulence factor: IL-10-dependent suppresssion of IL-12 production by filamentous haemagglutinin from Bordetella pertussis, Eur. J. Immunol., 30, 2000, p415 - 422
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI; URL

McGuirk, P. and Mills, K.H.G., A regulatory role for IL-4 in differential inflammatory responses in the lung following infection of mice primed with Th1- or Th2-inducing pertussis vaccines, Infection and Immunity, 68, (3), 2000, p1383 - 1391
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; URL

O'Neill, S.M., Brady, M.T., Callanan, J.J., Mulcahy, G, Joyce, P., Mills, K.H.G. and Dalton, J.P., Fasciola hepatica infection downregulates Th1 responses in mice, Parasite Immunol., 22, (3), 2000, p147 - 156
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; DOI; URL

The IL1 receptor / Toll-like receptor superfamily in, editor(s)J Oppenheim and M Feldmann , The Cytokine Reference, Academic Press, 2000, pp1565 - 1586, [O'Neill, LAJ and Dower, SJ ]
Book Chapter; Published; Peer Reviewed; Author Profile: LAONEILL

Omara, SM, O'Neill LAJ, The effects of the bacterial endotoxin lipopolysaccharide on synaptic transmission and plasticity in the CA1-subiculum pathway in vivo., unknown, 2000, 12, ISI Web of Science, 2000, pp250 - 250
Meeting Abstract; Published; Peer Reviewed; Author Profile: LAONEILL

RYAN, EJ, Mills, KH, MODULATION OF INNATE AND ACQUIRED IMMUNE RESPONSES BY ESCHERICHIA COLI HEAT-LABILE TOXIN: DISTINCT PRO- AND ANTI-INFLAMMATORY EFFECTS OF THE NONTOXIC AB COMPLEX AND THE ENZYME ACTIVITY, JOURNAL OF IMMUNOLOGY, 165, 2000, p5750 - 5759
Journal Article; Published; Peer Reviewed; Author Profile: MILLSK; URL

Christine E. Loscher, Sheila Donnelly, Kingston H. G. Mills, Marina A. Lynch, INTERLEUKIN-1 BETA-DEPENDENT CHANGES IN THE HIPPOCAMPUS FOLLOWING PARENTERAL IMMUNIZATION WITH A WHOLE CELL PERTUSSIS VACCINE, JOURNAL OF NEUROIMMUNOLOGY, 111, 2000, p68 - 76
Journal Article; Published; Peer Reviewed; Author Profiles: LYNCHMA MILLSK ; DOI; URL

Christine E. Loscher, Sheila Donnelly, Marina A. Lynch Kingston H. G. Mills, Induction of inflammatory cytokines in the brain following respiratory infection with bordetella pertussis, Journal of Neuroimmunology, 102, (2), 2000, p172 - 181
Journal Article; Published; Peer Reviewed; Author Profiles: LYNCHMA MILLSK ; DOI; URL

Monoamine oxidase assays. in, editor(s)S.J. Enna, M. Willias , J. W. Ferkany, T, Kenakin, R. E. Porsolt and J.P. Sullivan , Current Protocols in Pharmacology, New York , John Wiley , 2000, pp3.6.1 - 3.6.42 , [Tipton, K. F., Davey, G. and Motherway, M.]
Book Chapter; Published; Peer Reviewed; Author Profile: KTIPTON

Taurine 4: Taurine and Excitable Tissues in, editor(s)L. Della Corte, R. J. Huxtable, G.P. Sgaragli and K. F. Tipton , Advances in Experimental Medicine and Biology, Dordrecht, The Netherlands , Kluwer Academic/Plenum Publishers, 2000, pp1 - 664, [ ]
Book Chapter; Published; Peer Reviewed; Author Profile: KTIPTON

Inhibitors of monoamine oxidase and the pressor response to dietary amines in, editor(s)K. Magyar and E.S. Vizi , Milestones in Monoamine Oxidase Research: Discovery of (-)-Deprenyl, Budapest, Hungary, Medicina Publishing House, 2000, pp19 - 32, [Tipton, K. F. ]
Book Chapter; Published; Peer Reviewed; Author Profile: KTIPTON

Davey, G. P. and Tipton, K. F., Mitochondria, cell death and DNA damage. , Radiation Research , 2, 2000, p390 - 394
Journal Article; Published; Peer Reviewed; Author Profile: KTIPTON

Enzyme Classification and Nomenclature in, Encyclopedia of Life Sciences, UK, Macmillan Reference Co, 2000, ppArticle 710, 13 pp , [Tipton, K. F. and Boyce, S.]
Book Chapter; Published; Peer Reviewed; Author Profile: KTIPTON

Boyce, S. and Tipton, K. F., History of the enzyme nomenclature system, Bioinformatics, 16, 2000, p34 - 40
Journal Article; Published; Peer Reviewed; Author Profile: KTIPTON

Cunningham, C. M. and Tipton, K. F., Metabolism of taurine to sulphoacetaldehyde during oxidative stress, Advances in Experimental Medicine and Biology, 483, 2000, p383 - 388
Journal Article; Published; Peer Reviewed; Author Profile: KTIPTON

O'Byrne, M. B., Bolam, J. P., Hanley, J. J. and Tipton, K. F. , Tyrosine-hydroxylase immuno-reactive cells in the rat striatum following treatment with MPP+. , Advances in Experimental Medicine and Biology, 483, 2000, p369 - 374
Journal Article; Published; Peer Reviewed; Author Profile: KTIPTON

Capodarca, S., Cunningham, C. M., Bartolini, P., Tipton, K. F., Della Corte, L., Bianchi, L., Ward, R. J., Dachour, A., Quertemont, E., Lallemand, F. and De Witte, P., Effects of ethanol and glutamate agonist infusion on the outflow of sulphoacetaldehyde: Microdialysis studies, Advances in Experimental Medicine and Biology, 483, 2000, p397 - 304
Journal Article; Published; Peer Reviewed; Author Profile: KTIPTON

Palmi, M., Youmbi, G., Sgaragli, G. P., Meini, A., Benocci, A., Fusi, F., Frosini, M., Della Corte, L., Davey, L. and K.F. Tipton, K. F., The mitochondrial permeability transition and taurine, Advances in Experimental Medicine and Biology, 483, 2000, p87 - 96
Journal Article; Published; Peer Reviewed; Author Profile: KTIPTON

Lizcano, J. M., Unzeta. M. and Tipton, K. F., Time-dependent activation of the semicarbazide-sensitive amine oxidase (SSAO) from ox lung microsomes, 351, 2000, p789 - 794
Journal Article; Published; Peer Reviewed; Author Profile: KTIPTON

Lizcano, J. M., Unzeta, M. and Tipton, K. F., A spectrophotometric method for determining the oxidative deamination of methylamine by the amine oxidases, Analyt. Biochem, 286, 2000, p75 - 79
Journal Article; Published; Peer Reviewed; Author Profile: KTIPTON

Kelly, J. A., Slator, G. R., Tipton, K. F., Williams, C. H. and Bauer, K., Kinetic Investigation of the Specificity of Porcine Brain Thyrotropin-releasing Hormone-degrading Ectoenzyme for Thyrotropin-releasing Hormone-like Peptides, J. Biol. Chem, 275, 2000, p16746 - 16751
Journal Article; Published; Peer Reviewed; Author Profile: KTIPTON

O'Byrne, M. B. and Tipton, K. F., Taurine-induced attenuation of MPP+ neurotoxicity in vitro: a possible role for the GABA(A) subclass of GABA receptors, J. Neurochem, 74, 2000, p2087 - 2093
Journal Article; Published; Peer Reviewed; Author Profile: KTIPTON

Valoti, M., Fusi, F., Frosini, M., Pessina, F., Tipton, K. F. and Sgaragli, G. P., Cytochrome P450-dependent N-dealkylation of L-deprenyl in C57BL mouse liver microsomes: effects of in vivo pretreatment with ethanol, phenobarbital, beta-naphthoflavone and L-deprenyl. , Eur. J. Pharmacol, 391, 2000, p199 - 206
Journal Article; Published; Peer Reviewed; Author Profile: KTIPTON

Christine E. Loscher, Sheila Donnelly, Kingston H. G. Mills, and Marina A. Lynch, Interleukin-1â-dependent changes in the hippocampus following parenteral immunization with a whole cell pertussis vaccine , Journal of Neuroimmunology, 111, (1-2), 2000, p68 - 76
Journal Article; Published; Peer Reviewed; Author Profiles: MILLSK LYNCHMA ; DOI; URL